222 Matching Annotations
  1. Last 7 days
  2. www.sciencedirect.com www.sciencedirect.com
    The ATAC complex represses the transcriptional program of the autophagy-lysosome pathway via its E3 ubiquitin ligase activity
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    sciencedirect.com/science/article/pii/S2211124724013846
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    p53 induces circFRMD4A to suppress cancer development through glycolytic reprogramming and cuproptosis
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    sciencedirect.com/science/article/pii/S1097276524009183
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    Biased signaling by mutant EGFR underlies dependence on PKCα in lung adenocarcinoma
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    sciencedirect.com/science/article/pii/S2211124724013779
  5. Dec 2024
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    Lovastatin-mediated pharmacological inhibition of Formin protein DIAPH1 suppresses tumor immune escape and boosts immunotherapy response
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    sciencedirect.com/science/article/pii/S1567576924021593
  7. Nov 2024
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Chelating drug-induced labile Zn2+ with nanoparticle-encapsulated TPEN at low dose enhances lung cancer chemotherapy through inhibiting ABCB1
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  9. 52.53.155.43 52.53.155.43
    can-24-0529-html.html
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  10. Oct 2024
  11. www.sciencedirect.com www.sciencedirect.com
    Enhancer reprogramming underlies therapeutic utility of a SMARCA2 degrader in SMARCA4 mutant cancer
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    sciencedirect.com/science/article/pii/S2451945624003969
  12. link.springer.com link.springer.com
    Inhibition of EREG/ErbB/ERK by Astragaloside IV reversed taxol-resistance of non-small cell lung cancer through attenuation of stemness via TGFβ and Hedgehog signal pathway
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  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hypoxia-Induced Long Noncoding RNA HIF1A-AS2 Regulates Stability of MHC Class I Protein in Head and Neck Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11443317/
  14. Sep 2024
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    A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer
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    CircPOLA2 sensitizes non-small cell lung cancer cells to ferroptosis and suppresses tumorigenesis via the Merlin-YAP signaling pathway
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  17. www.nature.com www.nature.com
    Defective N-glycosylation of IL6 induces metastasis and tyrosine kinase inhibitor resistance in lung cancer
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  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A common druggable signature of oncogenic c-Myc, mutant KRAS and mutant p53 reveals functional redundancy and competition among oncogenes in cancer
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  19. Aug 2024
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transcriptomics Reveals the Mechanism of Platycodin D Targeting TGFβ for Anti-Lung Cancer Activity
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    The ribosomal protein L22 binds the MDM4 pre-mRNA and promotes exon skipping to activate p53 upon nucleolar stress
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  22. 52.53.155.43 52.53.155.43
    Molecular Oncology - 2023 - Pan-html.html
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  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of IDH3α Enhanced the Efficacy of Chemoimmunotherapy by Regulating Acidic Tumor Microenvironments
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  24. www.tandfonline.com www.tandfonline.com
    Comprehensive Explorations of CCL28 in Lung Adenocarcinoma Immunotherapy and Experimental Validation
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    Decoupling global biases and local interactions between cell biological variables
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  26. Jul 2024
  27. www.sciencedirect.com www.sciencedirect.com
    IRF4 requires ARID1A to establish plasma cell identity in multiple myeloma
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    Target fishing and mechanistic insights of the natural anticancer drug candidate chlorogenic acid
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  29. May 2024
  30. aacrjournals.org aacrjournals.org
    Bile acid metabolism mediates cholesterol homeostasis and promotes tumorigenesis in clear cell renal cell carcinoma
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  31. aacrjournals.org aacrjournals.org
    Cooperative armoring of CAR and TCR T-cells by T cell-restricted IL-15 and IL-21 universally enhances solid tumor efficacy
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  32. aacrjournals.org aacrjournals.org
    TNFRSF19 within the 13q12.12 risk locus functions as a lung cancer suppressor by binding Wnt3a to inhibit Wnt/β-catenin signaling.
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  33. www.sciencedirect.com www.sciencedirect.com
    Oncogenic fatty acid oxidation senses circadian disruption in sleep-deficiency-enhanced tumorigenesis
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  34. 52.53.155.43 52.53.155.43
    Therapeutic Implications of Ceritinib in Cholangiocarcinoma beyond ALK Expression and Mutation
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  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Synergy of EGFR and AURKA Inhibitors in KRAS-mutated Non–small Cell Lung Cancers
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  36. 52.53.155.43 52.53.155.43
    TERC promotes non-small cell lung cancer progression by facilitating the nuclear localization of TERT
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  37. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Disrupting the interaction between a p53 gain-of-function mutant and the transcriptional co-activator PC4 reverses drug resistance in cancer cells
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      DOI: 10.1002/1873-3468.14890

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  38. Apr 2024
  39. www.embopress.org www.embopress.org
    The regulatory relationship between NAMPT and PD-L1 in cancer and identification of a dual-targeting inhibitor
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      ATCC CRL-5803

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    embopress.org/doi/full/10.1038/s44321-024-00051-z
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HDAC10 inhibition represses melanoma cell growth and BRAF inhibitor resistance via upregulating SPARC expression
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      DOI: 10.1093/narcan/zcae018

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  41. www.sciencedirect.com www.sciencedirect.com
    Repurposing AS1411 for constructing ANM-PROTACs
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  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bisbiguanide analogs induce mitochondrial stress to inhibit lung cancer cell invasion
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      DOI: 10.1016/j.isci.2024.109591

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  43. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    DRD1 suppresses cell proliferation and reduces EGFR activation and PD-L1 expression in NSCLC
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      DOI: 10.1002/1878-0261.13608

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  44. www.sciencedirect.com www.sciencedirect.com
    Adhesion of Klebsiella Oxytoca to Bladder or Lung Epithelial Cells Is Promoted by the Presence of Other Opportunistic Pathogens
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      DOI: 10.1016/j.micpath.2024.106642

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  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Non-Viral DNA Delivery System Consisting of Multifunctional Chimaeric Peptide Fused with Zinc Finger Protein
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  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IL-17 induces NSCLC cell migration and invasion by elevating MMP19 gene transcription and expression through the interaction of p300-dependent STAT3-K631 acetylation and its Y705-phosphorylation
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  47. Mar 2024
  48. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Combining VPS34 inhibitors with STING agonists enhances type I interferon signaling and anti-tumor efficacy
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      DOI: 10.1002/1878-0261.13619

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  49. www.sciencedirect.com www.sciencedirect.com
    De novo steroidogenesis in tumor cells drives bone metastasis and osteoclastogenesis
    1
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  50. www.sciencedirect.com www.sciencedirect.com
    Low expression of lysosome-related genes KCNE1, NPC2, and SFTPD promote cancer cell proliferation and tumor associated M2 macrophage polarization in lung adenocarcinoma
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  51. Feb 2024
  52. 52.53.155.43 52.53.155.43
    d4-html.html
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  53. 52.53.155.43 52.53.155.43
    delet 4-html.html
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  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Diverse temporal and spatial mechanisms work, partially through Stanniocalcin-1, V-ATPase and senescence, to activate the extracellular ATP-mediated drug resistance in human cancer cells
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  55. www.biorxiv.org www.biorxiv.org
    A common druggable signature of oncogenic CMYC, mutant KRAS and mutant p53 reveals functional redundancy and competition of the oncogenes in cancer
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    Tumoral and stromal hMENA isoforms impact tertiary lymphoid structure localization in lung cancer and predict immune checkpoint blockade response in patients with cancer
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  57. www.biorxiv.org www.biorxiv.org
    HDAC10 blockade upregulates SPARC expression thereby repressing melanoma cell growth and BRAF inhibitor resistance
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    Targeting TOP2B as a vulnerability in aging and aging-related diseases
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    PHLDA2-mediated phosphatidic acid peroxidation triggers a distinct ferroptotic response during tumor suppression
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  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cooperation between PRMT1 and PRMT6 drives lung cancer health disparities among Black/African American men
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  61. www.sciencedirect.com www.sciencedirect.com
    SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway
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  62. Jan 2024
  63. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FBXL16 promotes cell growth and drug resistance in lung adenocarcinomas with KRAS mutation by stabilizing IRS1 and upregulating IRS1/AKT signaling
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  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Overexpression of MRPL19 in predicting poor prognosis and promoting the development of lung adenocarcinoma
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  65. www.cell.com www.cell.com
    p53-responsive CMBL reprograms glucose metabolism and suppresses cancer development by destabilizing phosphofructokinase PFKP
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  66. www.sciencedirect.com www.sciencedirect.com
    The pleiotropic enhancer enh9 promotes cell proliferation and migration in non-small cell lung cancer via ERMP1 and PD-L1
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  67. Dec 2023
  68. www.sciencedirect.com www.sciencedirect.com
    A helicase-independent role of DHX15 promotes MYC stability and acute leukemia cell survival
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  69. www.sciencedirect.com www.sciencedirect.com
    Engineering CD276/B7-H3-targeted antibody-drug conjugates with enhanced cancer-eradicating capability
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  70. Nov 2023
  71. www.sciencedirect.com www.sciencedirect.com
    Anti-tumor effect of PD-L1-targeting antagonistic aptamer-ASO delivery system with dual inhibitory function in immunotherapy
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  72. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Fast proliferating and slowly migrating non-small cell lung cancer cells are vulnerable to decitabine and retinoic acid combinatorial treatment
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  73. 52.53.155.43 52.53.155.43
    British J Pharmacology - 2023 - Chen - Identification of arnicolide C as a novel chemosensitizer to suppress mTOR E2F1-html.html
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    52.53.155.43/fa9809949a94f3d698a02ed4d13d532c010d3e91/British J Pharmacology - 2023 - Chen - Identification of arnicolide C as a novel chemosensitizer to suppress mTOR E2F1-html.html
  74. www.sciencedirect.com www.sciencedirect.com
    mTORC1 promotes cell growth via m6A-dependent mRNA degradation
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  75. Sep 2023
  76. link.springer.com link.springer.com
    A dual role for ERK-1/2 in the regulation of plasmin activity and cell migration in metastatic NSCLC-H1299 cells
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  77. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  78. Aug 2023
  79. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Canagliflozin mediates tumor suppression alone and in combination with radiotherapy in non-small cell lung cancer (NSCLC) through inhibition of HIF-1α
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  80. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
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  81. Jul 2023
  82. www.nature.com www.nature.com
    E3 ligase MG53 suppresses tumor growth by degrading cyclin D1
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  83. Jun 2023
  84. 52.53.155.43 52.53.155.43
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  85. May 2023
  86. 52.53.155.43 52.53.155.43
    Global identification of direct SWI/SNF targets reveals compensation by EP400
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  87. 52.53.155.43 52.53.155.43
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  88. aacrjournals.org aacrjournals.org
    Decoding the lncRNAome across diverse cellular stresses reveals core p53-effector pan-cancer suppressive lncRNAs
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  89. Apr 2023
  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RAB27B Drives a Cancer Stem Cell Phenotype in NSCLC Cells Through Enhanced Extracellular Vesicle Secretion
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  91. www.sciencedirect.com www.sciencedirect.com
    IKZF4 acts as a novel tumor suppressor in non–small cell lung cancer by suppressing Notch signaling pathway
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  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Intronic Cis-Element DR8 in hTERT Is Bound by Splicing Factor SF3B4 and Regulates hTERT Splicing in Non-Small Cell Lung Cancer
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  93. www.nature.com www.nature.com
    PLCG2 can exist in eccDNA and contribute to the metastasis of non-small cell lung cancer by regulating mitochondrial respiration
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  94. Mar 2023
  95. www.dovepress.com www.dovepress.com
    Comprehensive Explorations of CCL28 in Lung Adenocarcinoma Immunotherapy and Experimental Validation
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  96. link.springer.com link.springer.com
    S-adenosylhomocysteine hydrolase-like protein 1 (AHCYL1) inhibits lung cancer tumorigenesis by regulating cell plasticity
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  97. Jan 2023
  98. aacrjournals.org aacrjournals.org
    Loss of VOPP1 Contributes to BET Inhibitor Acquired Resistance in Non–Small Cell Lung Cancer Cells
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  99. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PhAc-ALGP-Dox, a Novel Anticancer Prodrug with Targeted Activation and Improved Therapeutic Index
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  100. Dec 2022
  101. www.sciencedirect.com www.sciencedirect.com
    EGFR-phosphorylated GDH1 harmonizes with RSK2 to drive CREB activation and tumor metastasis in EGFR-activated lung cancer
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  102. Oct 2022
  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Eprenetapopt triggers ferroptosis, inhibits NFS1 cysteine desulfurase, and synergizes with serine and glycine dietary restriction
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  104. Sep 2022
  105. www.jci.org www.jci.org
    Hematopoietic transcription factor GFI1 promotes anchorage independence by sustaining ERK activity in cancer cells
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  106. www.sciencedirect.com www.sciencedirect.com
    The molecular network of the proteasome machinery inhibition response is orchestrated by HSP70, revealing vulnerabilities in cancer cells
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    Analyses of rare predisposing variants of lung cancer in 6,004 whole genomes in Chinese
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  108. Aug 2022
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    Lung fibrogenic microenvironment in mouse reconstitutes human alveolar structure and lung tumor
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  110. 52.53.155.43 52.53.155.43
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  111. 52.53.155.43 52.53.155.43
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  112. aacrjournals.org aacrjournals.org
    Developmental pathways are epigenetically reprogrammed during lung cancer brain metastasis
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  113. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Cancer-associated fibroblasts in nonsmall cell lung cancer: From molecular mechanisms to clinical implications
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      DOI: 10.1002/ijc.34127

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  114. molecular-cancer.biomedcentral.com molecular-cancer.biomedcentral.com
    BTApep-TAT peptide inhibits ADP-ribosylation of BORIS to induce DNA damage in cancer
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      DOI: 10.1186/s12943-022-01621-w

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  115. Jun 2022
  116. www.sciencedirect.com www.sciencedirect.com
    A small-molecule Skp1 inhibitor elicits cell death by p53-dependent mechanism
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  117. www.sciencedirect.com www.sciencedirect.com
    Poroptosis: a form of cell death depending on plasma membrane nanopores formation
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      ATCCCat # CRL-5803

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  118. www.sciencedirect.com www.sciencedirect.com
    MDM2 binds and ubiquitinates PARP1 to enhance DNA replication fork progression
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  119. May 2022
  120. www.sciencedirect.com www.sciencedirect.com
    SETD4-mediated KU70 methylation suppresses apoptosis
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      ATCCCat#CRL-5803

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  121. www.cell.com www.cell.com
    Systematic discovery of mutation-directed neo-protein-protein interactions in cancer
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  122. Apr 2022
  123. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SARS-CoV-2 variants C.1.2 and B.1.621 (Mu) partially evade neutralization by antibodies elicited upon infection or vaccination
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      RRID: CVCL_0060

      DOI: 10.1016/j.celrep.2022.110754

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  124. www.sciencedirect.com www.sciencedirect.com
    Purification and cryo-EM structure determination of VCP/p97 dodecamers from mammalian and bacterial cells
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  125. www.sciencedirect.com www.sciencedirect.com
    Cellular signals converge at the NOX2-SHP-2 axis to induce reductive carboxylation in cancer cells
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  126. www.sciencedirect.com www.sciencedirect.com
    Repurposing antiparasitic antimonials to noncovalently rescue temperature-sensitive p53 mutations
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    Nuclear microRNAs release paused Pol II via the DDX21-CDK9 complex
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  128. www.sciencedirect.com www.sciencedirect.com
    Heat-induced SIRT1-mediated H4K16ac deacetylation impairs resection and SMARCAD1 recruitment to double strand breaks
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  129. Mar 2022
  130. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cross-species tropism and antigenic landscapes of circulating SARS-CoV-2 variants
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  131. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Profiling of diverse tumor types establishes the broad utility of VHL-based ProTaCs and triages candidate ubiquitin ligases
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  132. www.sciencedirect.com www.sciencedirect.com
    A reversible metabolic stress-sensitive regulation of CRMP2A orchestrates EMT/stemness and increases metastatic potential in cancer
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    Micropeptide PACMP inhibition elicits synthetic lethal effects by decreasing CtIP and poly(ADP-ribosyl)ation
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  134. Feb 2022
  135. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Etoposide-induced DNA damage is increased in p53 mutants: identification of ATR and other genes that influence effects of p53 mutations on Top2-induced cytotoxicity
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      DOI: 10.18632/oncotarget.28195

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  136. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    LncRNA FENDRR-mediated tumor suppression and tumor-immune microenvironment changes in non-small cell lung cancer
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  137. www.sciencedirect.com www.sciencedirect.com
    Optogenetic EB1 inactivation shortens metaphase spindles by disrupting cortical force-producing interactions with astral microtubules
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  138. Jan 2022
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    MEK inhibition overcomes chemoimmunotherapy resistance by inducing CXCL10 in cancer cells
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    Senescence marker protein 30 inhibits tumor growth by reducing HDAC4 expression in non-small cell lung cancer
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  141. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Nedd9 restrains autophagy to limit growth of early stage non-small cell lung cancer
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      DOI: 10.1158/0008-5472.CAN-20-3626

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    ncbi.nlm.nih.gov/pmc/articles/PMC8277748/
  142. Dec 2021
  143. www.sciencedirect.com www.sciencedirect.com
    Protein modifications throughout the lung cancer proteome unravel the cancer-specific regulation of glycolysis
    1
    1. scibot 23 Dec 2021
      CRL-5803

      DOI: 10.1016/j.celrep.2021.110137

      Resource: (NCI-DTP Cat# NCI-H1299, RRID:CVCL_0060)

      Curator: @Naa003

      SciCrunch record: RRID:CVCL_0060

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      RRID:CVCL_0060 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S2211124721016338
  144. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Halofuginone Sensitizes Lung Cancer Organoids to Cisplatin via Suppressing PI3K/AKT and MAPK Signaling Pathways
    1
    1. scibot 11 Dec 2021
      RRID:CVCL_0060

      DOI: 10.3389/fcell.2021.773048

      Resource: (NCI-DTP Cat# NCI-H1299, RRID:CVCL_0060)

      Curator: @scibot

      SciCrunch record: RRID:CVCL_0060

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      RRID:CVCL_0060
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    ncbi.nlm.nih.gov/pmc/articles/PMC8652204/
  145. Nov 2021
  146. mct.aacrjournals.org mct.aacrjournals.org
    SAGE1: a Potential Target Antigen for Lung Cancer T-Cell Immunotherapy
    1
    1. scibot 24 Nov 2021
      RRID: CVCL_0060

      DOI: 10.1158/1535-7163.MCT-21-0203

      Resource: (NCI-DTP Cat# NCI-H1299, RRID:CVCL_0060)

      Curator: @Naa003

      SciCrunch record: RRID:CVCL_0060

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    mct.aacrjournals.org/content/20/11/2302
  147. www.sciencedirect.com www.sciencedirect.com
    HNRNPA2B1 as a trigger of RNA switch modulates the miRNA-mediated regulation of CDK6
    1
    1. scibot 09 Nov 2021
      CRL-5803

      DOI: 10.1016/j.isci.2021.103345

      Resource: (NCI-DTP Cat# NCI-H1299, RRID:CVCL_0060)

      Curator: @Naa003

      SciCrunch record: RRID:CVCL_0060

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      RRIDCUR:Missing RRID:CVCL_0060
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    sciencedirect.com/science/article/pii/S2589004221013146
  148. www.sciencedirect.com www.sciencedirect.com
    FARP1, ARHGEF39, and TIAM2 are essential receptor tyrosine kinase effectors for Rac1-dependent cell motility in human lung adenocarcinoma
    1
    1. scibot 03 Nov 2021
      CRL-5803

      DOI: 10.1016/j.celrep.2021.109905

      Resource: (NCI-DTP Cat# NCI-H1299, RRID:CVCL_0060)

      Curator: @Naa003

      SciCrunch record: RRID:CVCL_0060

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      RRIDCUR:Missing RRID:CVCL_0060
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    sciencedirect.com/science/article/pii/S2211124721013759
  149. Oct 2021
  150. www.sciencedirect.com www.sciencedirect.com
    RNF8-mediated regulation of Akt promotes lung cancer cell survival and resistance to DNA damage
    1
    1. scibot 21 Oct 2021
      CRL-5803

      DOI: 10.1016/j.celrep.2021.109854

      Resource: (NCI-DTP Cat# NCI-H1299, RRID:CVCL_0060)

      Curator: @Naa003

      SciCrunch record: RRID:CVCL_0060

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      RRID:CVCL_0060 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S2211124721013218
  151. link.springer.com link.springer.com
    EGFR transcriptionally upregulates UTX via STAT3 in non-small cell lung cancer
    1