219 Matching Annotations
  1. Last 7 days
  2. www.sciencedirect.com www.sciencedirect.com
    Lovastatin-mediated pharmacological inhibition of Formin protein DIAPH1 suppresses tumor immune escape and boosts immunotherapy response
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      DOI: 10.1016/j.intimp.2024.113637

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    sciencedirect.com/science/article/pii/S1567576924021593
  3. Nov 2024
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Chelating drug-induced labile Zn2+ with nanoparticle-encapsulated TPEN at low dose enhances lung cancer chemotherapy through inhibiting ABCB1
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      ATCC CRL-5803

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    pmc.ncbi.nlm.nih.gov/articles/PMC11539588/
  5. 52.53.155.43 52.53.155.43
    can-24-0529-html.html
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  6. Oct 2024
  7. www.sciencedirect.com www.sciencedirect.com
    Enhancer reprogramming underlies therapeutic utility of a SMARCA2 degrader in SMARCA4 mutant cancer
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    sciencedirect.com/science/article/pii/S2451945624003969
  8. link.springer.com link.springer.com
    Inhibition of EREG/ErbB/ERK by Astragaloside IV reversed taxol-resistance of non-small cell lung cancer through attenuation of stemness via TGFβ and Hedgehog signal pathway
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    1. scibot 08 Oct 2024
      RRID: CVCL_0060

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    link.springer.com/article/10.1007/s13402-024-00999-7
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hypoxia-Induced Long Noncoding RNA HIF1A-AS2 Regulates Stability of MHC Class I Protein in Head and Neck Cancer
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      DOI: 10.1158/2326-6066.CIR-23-0622

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    ncbi.nlm.nih.gov/pmc/articles/PMC11443317/
  10. Sep 2024
  11. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer
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  12. www.sciencedirect.com www.sciencedirect.com
    CircPOLA2 sensitizes non-small cell lung cancer cells to ferroptosis and suppresses tumorigenesis via the Merlin-YAP signaling pathway
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    sciencedirect.com/science/article/pii/S2589004224020571
  13. www.nature.com www.nature.com
    Defective N-glycosylation of IL6 induces metastasis and tyrosine kinase inhibitor resistance in lung cancer
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      DOI: 10.1038/s41467-024-51831-7

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  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A common druggable signature of oncogenic c-Myc, mutant KRAS and mutant p53 reveals functional redundancy and competition among oncogenes in cancer
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      DOI: 10.1038/s41419-024-06965-3

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  15. Aug 2024
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transcriptomics Reveals the Mechanism of Platycodin D Targeting TGFβ for Anti-Lung Cancer Activity
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    1. scibot 30 Aug 2024
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  17. www.sciencedirect.com www.sciencedirect.com
    The ribosomal protein L22 binds the MDM4 pre-mRNA and promotes exon skipping to activate p53 upon nucleolar stress
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      DOI: 10.1016/j.celrep.2024.114610

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  18. 52.53.155.43 52.53.155.43
    Molecular Oncology - 2023 - Pan-html.html
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  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of IDH3α Enhanced the Efficacy of Chemoimmunotherapy by Regulating Acidic Tumor Microenvironments
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      DOI: 10.3390/cancers15061802

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    ncbi.nlm.nih.gov/pmc/articles/PMC10046804/
  20. www.tandfonline.com www.tandfonline.com
    Comprehensive Explorations of CCL28 in Lung Adenocarcinoma Immunotherapy and Experimental Validation
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      DOI: 10.2147/JIR.S399193

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  21. elifesciences.org elifesciences.org
    Decoupling global biases and local interactions between cell biological variables
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      DOI: 10.7554/eLife.22323

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    elifesciences.org/content/6/e22323
  22. Jul 2024
  23. www.sciencedirect.com www.sciencedirect.com
    IRF4 requires ARID1A to establish plasma cell identity in multiple myeloma
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    sciencedirect.com/science/article/pii/S1535610824002174
  24. www.sciencedirect.com www.sciencedirect.com
    Target fishing and mechanistic insights of the natural anticancer drug candidate chlorogenic acid
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  25. May 2024
  26. aacrjournals.org aacrjournals.org
    Bile acid metabolism mediates cholesterol homeostasis and promotes tumorigenesis in clear cell renal cell carcinoma
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    1. scibot 23 May 2024
      RRID:CVCL_0060

      DOI: 10.1158/0008-5472.CAN-23-0821

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    aacrjournals.org/cancerres/article/84/10/1570/745316/Bile-Acid-Metabolism-Mediates-Cholesterol
  27. aacrjournals.org aacrjournals.org
    Cooperative armoring of CAR and TCR T-cells by T cell-restricted IL-15 and IL-21 universally enhances solid tumor efficacy
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    1. scibot 23 May 2024
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      DOI: 10.1158/1078-0432.CCR-23-1872

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    aacrjournals.org/clincancerres/article/30/8/1555/742121/Cooperative-Armoring-of-CAR-and-TCR-T-Cells-by-T
  28. aacrjournals.org aacrjournals.org
    TNFRSF19 within the 13q12.12 risk locus functions as a lung cancer suppressor by binding Wnt3a to inhibit Wnt/β-catenin signaling.
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      DOI: 10.1158/1541-7786.MCR-23-0109

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  29. www.sciencedirect.com www.sciencedirect.com
    Oncogenic fatty acid oxidation senses circadian disruption in sleep-deficiency-enhanced tumorigenesis
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  30. 52.53.155.43 52.53.155.43
    Therapeutic Implications of Ceritinib in Cholangiocarcinoma beyond ALK Expression and Mutation
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      DOI: 10.3390/ph17020197

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  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Synergy of EGFR and AURKA Inhibitors in KRAS-mutated Non–small Cell Lung Cancers
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      DOI: 10.1158/2767-9764.CRC-23-0482

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  32. 52.53.155.43 52.53.155.43
    TERC promotes non-small cell lung cancer progression by facilitating the nuclear localization of TERT
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    1. scibot 09 May 2024
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  33. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Disrupting the interaction between a p53 gain-of-function mutant and the transcriptional co-activator PC4 reverses drug resistance in cancer cells
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      DOI: 10.1002/1873-3468.14890

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  34. Apr 2024
  35. www.embopress.org www.embopress.org
    The regulatory relationship between NAMPT and PD-L1 in cancer and identification of a dual-targeting inhibitor
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      DOI: 10.1038/s44321-024-00051-z

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      ATCC CRL-5803

      DOI: 10.1038/s44321-024-00051-z

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    embopress.org/doi/full/10.1038/s44321-024-00051-z
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HDAC10 inhibition represses melanoma cell growth and BRAF inhibitor resistance via upregulating SPARC expression
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      RRID:CVCL_0060

      DOI: 10.1093/narcan/zcae018

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    ncbi.nlm.nih.gov/pmc/articles/PMC11034028/
  37. www.sciencedirect.com www.sciencedirect.com
    Repurposing AS1411 for constructing ANM-PROTACs
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      RRID:CVCL_0060

      DOI: 10.1016/j.chembiol.2024.03.011

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    sciencedirect.com/science/article/pii/S2451945624001272
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bisbiguanide analogs induce mitochondrial stress to inhibit lung cancer cell invasion
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      RRID:CVCL_0060

      DOI: 10.1016/j.isci.2024.109591

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    ncbi.nlm.nih.gov/pmc/articles/PMC11022046/
  39. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    DRD1 suppresses cell proliferation and reduces EGFR activation and PD-L1 expression in NSCLC
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      RRID:CVCL_0060

      DOI: 10.1002/1878-0261.13608

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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.13608
  40. www.sciencedirect.com www.sciencedirect.com
    Adhesion of Klebsiella Oxytoca to Bladder or Lung Epithelial Cells Is Promoted by the Presence of Other Opportunistic Pathogens
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      DOI: 10.1016/j.micpath.2024.106642

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    sciencedirect.com/science/article/pii/S0882401024001098
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Non-Viral DNA Delivery System Consisting of Multifunctional Chimaeric Peptide Fused with Zinc Finger Protein
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      RRID:CVCL_0060

      DOI: 10.1016/j.isci.2024.109464

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    ncbi.nlm.nih.gov/pmc/articles/PMC10981093/
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IL-17 induces NSCLC cell migration and invasion by elevating MMP19 gene transcription and expression through the interaction of p300-dependent STAT3-K631 acetylation and its Y705-phosphorylation
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      RRID:CVCL_0060

      DOI: 10.32604/or.2023.031053

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    ncbi.nlm.nih.gov/pmc/articles/PMC10972722/
  43. Mar 2024
  44. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Combining VPS34 inhibitors with STING agonists enhances type I interferon signaling and anti-tumor efficacy
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    1. scibot 28 Mar 2024
      RRID:CVCL_0060

      DOI: 10.1002/1878-0261.13619

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  45. www.sciencedirect.com www.sciencedirect.com
    De novo steroidogenesis in tumor cells drives bone metastasis and osteoclastogenesis
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      Cat# CRL-5803

      DOI: 10.1016/j.celrep.2024.113936

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    sciencedirect.com/science/article/pii/S221112472400264X
  46. www.sciencedirect.com www.sciencedirect.com
    Low expression of lysosome-related genes KCNE1, NPC2, and SFTPD promote cancer cell proliferation and tumor associated M2 macrophage polarization in lung adenocarcinoma
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  47. Feb 2024
  48. 52.53.155.43 52.53.155.43
    d4-html.html
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  49. 52.53.155.43 52.53.155.43
    delet 4-html.html
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  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Diverse temporal and spatial mechanisms work, partially through Stanniocalcin-1, V-ATPase and senescence, to activate the extracellular ATP-mediated drug resistance in human cancer cells
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  51. www.biorxiv.org www.biorxiv.org
    A common druggable signature of oncogenic CMYC, mutant KRAS and mutant p53 reveals functional redundancy and competition of the oncogenes in cancer
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    Tumoral and stromal hMENA isoforms impact tertiary lymphoid structure localization in lung cancer and predict immune checkpoint blockade response in patients with cancer
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  53. www.biorxiv.org www.biorxiv.org
    HDAC10 blockade upregulates SPARC expression thereby repressing melanoma cell growth and BRAF inhibitor resistance
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    Targeting TOP2B as a vulnerability in aging and aging-related diseases
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    PHLDA2-mediated phosphatidic acid peroxidation triggers a distinct ferroptotic response during tumor suppression
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  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cooperation between PRMT1 and PRMT6 drives lung cancer health disparities among Black/African American men
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  57. www.sciencedirect.com www.sciencedirect.com
    SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway
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  58. Jan 2024
  59. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FBXL16 promotes cell growth and drug resistance in lung adenocarcinomas with KRAS mutation by stabilizing IRS1 and upregulating IRS1/AKT signaling
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  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Overexpression of MRPL19 in predicting poor prognosis and promoting the development of lung adenocarcinoma
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  61. www.cell.com www.cell.com
    p53-responsive CMBL reprograms glucose metabolism and suppresses cancer development by destabilizing phosphofructokinase PFKP
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  62. www.sciencedirect.com www.sciencedirect.com
    The pleiotropic enhancer enh9 promotes cell proliferation and migration in non-small cell lung cancer via ERMP1 and PD-L1
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  63. Dec 2023
  64. www.sciencedirect.com www.sciencedirect.com
    A helicase-independent role of DHX15 promotes MYC stability and acute leukemia cell survival
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      ATCCCat# CRL-5803

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  65. www.sciencedirect.com www.sciencedirect.com
    Engineering CD276/B7-H3-targeted antibody-drug conjugates with enhanced cancer-eradicating capability
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  66. Nov 2023
  67. www.sciencedirect.com www.sciencedirect.com
    Anti-tumor effect of PD-L1-targeting antagonistic aptamer-ASO delivery system with dual inhibitory function in immunotherapy
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  68. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Fast proliferating and slowly migrating non-small cell lung cancer cells are vulnerable to decitabine and retinoic acid combinatorial treatment
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  69. 52.53.155.43 52.53.155.43
    British J Pharmacology - 2023 - Chen - Identification of arnicolide C as a novel chemosensitizer to suppress mTOR E2F1-html.html
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  70. www.sciencedirect.com www.sciencedirect.com
    mTORC1 promotes cell growth via m6A-dependent mRNA degradation
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  71. Sep 2023
  72. link.springer.com link.springer.com
    A dual role for ERK-1/2 in the regulation of plasmin activity and cell migration in metastatic NSCLC-H1299 cells
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  73. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  74. Aug 2023
  75. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Canagliflozin mediates tumor suppression alone and in combination with radiotherapy in non-small cell lung cancer (NSCLC) through inhibition of HIF-1α
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  76. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
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  77. Jul 2023
  78. www.nature.com www.nature.com
    E3 ligase MG53 suppresses tumor growth by degrading cyclin D1
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  79. Jun 2023
  80. 52.53.155.43 52.53.155.43
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  81. May 2023
  82. 52.53.155.43 52.53.155.43
    Global identification of direct SWI/SNF targets reveals compensation by EP400
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  83. 52.53.155.43 52.53.155.43
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  84. aacrjournals.org aacrjournals.org
    Decoding the lncRNAome across diverse cellular stresses reveals core p53-effector pan-cancer suppressive lncRNAs
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  85. Apr 2023
  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RAB27B Drives a Cancer Stem Cell Phenotype in NSCLC Cells Through Enhanced Extracellular Vesicle Secretion
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  87. www.sciencedirect.com www.sciencedirect.com
    IKZF4 acts as a novel tumor suppressor in non–small cell lung cancer by suppressing Notch signaling pathway
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  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Intronic Cis-Element DR8 in hTERT Is Bound by Splicing Factor SF3B4 and Regulates hTERT Splicing in Non-Small Cell Lung Cancer
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  89. www.nature.com www.nature.com
    PLCG2 can exist in eccDNA and contribute to the metastasis of non-small cell lung cancer by regulating mitochondrial respiration
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  90. Mar 2023
  91. www.dovepress.com www.dovepress.com
    Comprehensive Explorations of CCL28 in Lung Adenocarcinoma Immunotherapy and Experimental Validation
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  92. link.springer.com link.springer.com
    S-adenosylhomocysteine hydrolase-like protein 1 (AHCYL1) inhibits lung cancer tumorigenesis by regulating cell plasticity
    1
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    link.springer.com/article/10.1186/s13062-023-00364-y
  93. Jan 2023
  94. aacrjournals.org aacrjournals.org
    Loss of VOPP1 Contributes to BET Inhibitor Acquired Resistance in Non–Small Cell Lung Cancer Cells
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      DOI: 10.1158/1541-7786.MCR-21-1000

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  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PhAc-ALGP-Dox, a Novel Anticancer Prodrug with Targeted Activation and Improved Therapeutic Index
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      CVCL_0060

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  96. Dec 2022
  97. www.sciencedirect.com www.sciencedirect.com
    EGFR-phosphorylated GDH1 harmonizes with RSK2 to drive CREB activation and tumor metastasis in EGFR-activated lung cancer
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  98. Oct 2022
  99. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Eprenetapopt triggers ferroptosis, inhibits NFS1 cysteine desulfurase, and synergizes with serine and glycine dietary restriction
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      DOI: 10.1126/sciadv.abm9427

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  100. Sep 2022
  101. www.jci.org www.jci.org
    Hematopoietic transcription factor GFI1 promotes anchorage independence by sustaining ERK activity in cancer cells
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  102. www.sciencedirect.com www.sciencedirect.com
    The molecular network of the proteasome machinery inhibition response is orchestrated by HSP70, revealing vulnerabilities in cancer cells
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  103. www.sciencedirect.com www.sciencedirect.com
    Analyses of rare predisposing variants of lung cancer in 6,004 whole genomes in Chinese
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  104. Aug 2022
  105. www.sciencedirect.com www.sciencedirect.com
    Lung fibrogenic microenvironment in mouse reconstitutes human alveolar structure and lung tumor
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      ATCCCRL-5803

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  106. 52.53.155.43 52.53.155.43
    149551.1-20220712091612-covered-e0fd13ba177f913fd3156f593ead4cfd-html.html
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  107. 52.53.155.43 52.53.155.43
    mcr-21-0058-html.html
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  108. aacrjournals.org aacrjournals.org
    Developmental pathways are epigenetically reprogrammed during lung cancer brain metastasis
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    aacrjournals.org/cancerres/article/82/15/2692/707331/Developmental-Pathways-Are-Epigenetically
  109. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Cancer-associated fibroblasts in nonsmall cell lung cancer: From molecular mechanisms to clinical implications
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      DOI: 10.1002/ijc.34127

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  110. molecular-cancer.biomedcentral.com molecular-cancer.biomedcentral.com
    BTApep-TAT peptide inhibits ADP-ribosylation of BORIS to induce DNA damage in cancer
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      DOI: 10.1186/s12943-022-01621-w

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  111. Jun 2022
  112. www.sciencedirect.com www.sciencedirect.com
    A small-molecule Skp1 inhibitor elicits cell death by p53-dependent mechanism
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      RRID:CVCL_0060

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  113. www.sciencedirect.com www.sciencedirect.com
    Poroptosis: a form of cell death depending on plasma membrane nanopores formation
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      ATCCCat # CRL-5803

      DOI: 10.1016/j.isci.2022.104481

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  114. www.sciencedirect.com www.sciencedirect.com
    MDM2 binds and ubiquitinates PARP1 to enhance DNA replication fork progression
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  115. May 2022
  116. www.sciencedirect.com www.sciencedirect.com
    SETD4-mediated KU70 methylation suppresses apoptosis
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      ATCCCat#CRL-5803

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  117. www.cell.com www.cell.com
    Systematic discovery of mutation-directed neo-protein-protein interactions in cancer
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  118. Apr 2022
  119. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SARS-CoV-2 variants C.1.2 and B.1.621 (Mu) partially evade neutralization by antibodies elicited upon infection or vaccination
    2
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      RRID: CVCL_0060

      DOI: 10.1016/j.celrep.2022.110754

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  120. www.sciencedirect.com www.sciencedirect.com
    Purification and cryo-EM structure determination of VCP/p97 dodecamers from mammalian and bacterial cells
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      ATCCCRL-5803

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  121. www.sciencedirect.com www.sciencedirect.com
    Cellular signals converge at the NOX2-SHP-2 axis to induce reductive carboxylation in cancer cells
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      DOI: 10.1016/j.chembiol.2022.03.010

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  122. www.sciencedirect.com www.sciencedirect.com
    Repurposing antiparasitic antimonials to noncovalently rescue temperature-sensitive p53 mutations
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      ATCCCRL-5803

      DOI: 10.1016/j.celrep.2022.110622

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  123. www.sciencedirect.com www.sciencedirect.com
    Nuclear microRNAs release paused Pol II via the DDX21-CDK9 complex
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  124. www.sciencedirect.com www.sciencedirect.com
    Heat-induced SIRT1-mediated H4K16ac deacetylation impairs resection and SMARCAD1 recruitment to double strand breaks
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  125. Mar 2022
  126. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cross-species tropism and antigenic landscapes of circulating SARS-CoV-2 variants
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      RRID:CVCL_0060

      DOI: 10.1016/j.celrep.2022.110558

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  127. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Profiling of diverse tumor types establishes the broad utility of VHL-based ProTaCs and triages candidate ubiquitin ligases
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  128. www.sciencedirect.com www.sciencedirect.com
    A reversible metabolic stress-sensitive regulation of CRMP2A orchestrates EMT/stemness and increases metastatic potential in cancer
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      ATCCCRL-5803

      DOI: 10.1016/j.celrep.2022.110511

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  129. www.sciencedirect.com www.sciencedirect.com
    Micropeptide PACMP inhibition elicits synthetic lethal effects by decreasing CtIP and poly(ADP-ribosyl)ation
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      DOI: 10.1016/j.molcel.2022.01.020

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  130. Feb 2022
  131. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Etoposide-induced DNA damage is increased in p53 mutants: identification of ATR and other genes that influence effects of p53 mutations on Top2-induced cytotoxicity
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      DOI: 10.18632/oncotarget.28195

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  132. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    LncRNA FENDRR-mediated tumor suppression and tumor-immune microenvironment changes in non-small cell lung cancer
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      DOI: 10.21037/tcr-20-2147

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  133. www.sciencedirect.com www.sciencedirect.com
    Optogenetic EB1 inactivation shortens metaphase spindles by disrupting cortical force-producing interactions with astral microtubules
    2
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      ATCCCRL-5803

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  134. Jan 2022
  135. www.sciencedirect.com www.sciencedirect.com
    MEK inhibition overcomes chemoimmunotherapy resistance by inducing CXCL10 in cancer cells
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  136. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Senescence marker protein 30 inhibits tumor growth by reducing HDAC4 expression in non-small cell lung cancer
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  137. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Nedd9 restrains autophagy to limit growth of early stage non-small cell lung cancer
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      DOI: 10.1158/0008-5472.CAN-20-3626

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    ncbi.nlm.nih.gov/pmc/articles/PMC8277748/
  138. Dec 2021
  139. www.sciencedirect.com www.sciencedirect.com
    Protein modifications throughout the lung cancer proteome unravel the cancer-specific regulation of glycolysis
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      CRL-5803

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  140. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Halofuginone Sensitizes Lung Cancer Organoids to Cisplatin via Suppressing PI3K/AKT and MAPK Signaling Pathways
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      DOI: 10.3389/fcell.2021.773048

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  141. Nov 2021
  142. mct.aacrjournals.org mct.aacrjournals.org
    SAGE1: a Potential Target Antigen for Lung Cancer T-Cell Immunotherapy
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      RRID: CVCL_0060

      DOI: 10.1158/1535-7163.MCT-21-0203

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  143. www.sciencedirect.com www.sciencedirect.com
    HNRNPA2B1 as a trigger of RNA switch modulates the miRNA-mediated regulation of CDK6
    1
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      CRL-5803

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  144. www.sciencedirect.com www.sciencedirect.com
    FARP1, ARHGEF39, and TIAM2 are essential receptor tyrosine kinase effectors for Rac1-dependent cell motility in human lung adenocarcinoma
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      CRL-5803

      DOI: 10.1016/j.celrep.2021.109905

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  145. Oct 2021
  146. www.sciencedirect.com www.sciencedirect.com
    RNF8-mediated regulation of Akt promotes lung cancer cell survival and resistance to DNA damage
    1
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      CRL-5803

      DOI: 10.1016/j.celrep.2021.109854

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  147. link.springer.com link.springer.com
    EGFR transcriptionally upregulates UTX via STAT3 in non-small cell lung cancer
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      RRID:CVCL_0060

      DOI: 10.1007/s00432-021-03800-6

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  148. www.sciencedirect.com www.sciencedirect.com
    Quantitative differences between cyclin-dependent kinases underlie the unique functions of CDK1 in human cells
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      CRL-5803

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  149. Sep 2021
  150. www.sciencedirect.com www.sciencedirect.com
    Oncogene-dependent sloppiness in mRNA translation
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      RRID:CVCL_0060

      DOI: 10.1016/j.molcel.2021.09.002

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  151. www.sciencedirect.com www.sciencedirect.com
    Multiplatform discovery and regulatory function analysis of structural variations in non-small cell lung carcinoma
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      RRID:CVCL_0060

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  152. Aug 2021
  153. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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      RRID:CVCL_0060

      DOI: 10.1016/j.ebiom.2018.11.007

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  154. www.sciencedirect.com www.sciencedirect.com
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      RRID:CVCL_0060

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  156. www.sciencedirect.com www.sciencedirect.com
    Gene copy-number changes and chromosomal instability induced by aneuploidy confer resistance to chemotherapy
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  157. www.nature.com www.nature.com
    Stromal induction of BRD4 phosphorylation Results in Chromatin Remodeling and BET inhibitor Resistance in Colorectal Cancer
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      DOI: 10.1038/s41467-021-24687-4

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  158. elifesciences.org elifesciences.org
    Decoupling global biases and local interactions between cell biological variables
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      RRID:CVCL_0060

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  159. www.sciencedirect.com www.sciencedirect.com
    RUVBL1/RUVBL2 ATPase Activity Drives PAQosome Maturation, DNA Replication and Radioresistance in Lung Cancer
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      RRID:CVCL_0060

      DOI: 10.1016/j.chembiol.2019.12.005

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  160. www.sciencedirect.com www.sciencedirect.com
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      RRID:CVCL_0060

      DOI: 10.1016/j.ebiom.2019.05.028

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  161. Jul 2021
  162. www.sciencedirect.com www.sciencedirect.com
    Three optimized assays for the evaluation of compounds that can rescue p53 mutants
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      CRL-5803

      DOI: 10.1016/j.xpro.2021.100688

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  163. link.springer.com link.springer.com
    miR-762 activation confers acquired resistance to gefitinib in non-small cell lung cancer
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      NCI-H1299

      DOI: 10.1186/s12885-019-6416-4

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  164. www.sciencedirect.com www.sciencedirect.com
    EED-Targeted PROTACs Degrade EED, EZH2, and SUZ12 in the PRC2 Complex
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    1. scibot 31 Jul 2021
      NCI-H1299

      DOI: 10.1016/j.chembiol.2019.11.004

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  165. www.sciencedirect.com www.sciencedirect.com
    Membrane Tension Orchestrates Rear Retraction in Matrix-Directed Cell Migration
    1
    1. scibot 30 Jul 2021
      Human: H1299 lung cancer cell line

      DOI: 10.1016/j.devcel.2019.09.006

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  166. www.sciencedirect.com www.sciencedirect.com
    Synthetic Lethal Interaction of SHOC2 Depletion with MEK Inhibition in RAS-Driven Cancers
    1
    1. scibot 30 Jul 2021
      NCI-H1299

      DOI: 10.1016/j.celrep.2019.08.090

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    sciencedirect.com/science/article/pii/S2211124719311520
  167. www.sciencedirect.com www.sciencedirect.com
    Removal of N-Linked Glycosylation Enhances PD-L1 Detection and Predicts Anti-PD-1/PD-L1 Therapeutic Efficacy
    1
    1. scibot 29 Jul 2021
      H1299

      DOI: 10.1016/j.ccell.2019.06.008

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    sciencedirect.com/science/article/pii/S1535610819302995
  168. www.sciencedirect.com www.sciencedirect.com
    Nuclear PGK1 Alleviates ADP-Dependent Inhibition of CDC7 to Promote DNA Replication
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    1. scibot 27 Jul 2021
      CRL-5803

      DOI: 10.1016/j.molcel.2018.09.007

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  169. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A small molecule drug promoting miRNA processing induces alternative splicing of MdmX transcript and rescues p53 activity in human cancer cells overexpressing MdmX protein
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      H1299

      DOI: 10.1371/journal.pone.0185801

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    ncbi.nlm.nih.gov/pmc/articles/PMC5626491/
  170. www.sciencedirect.com www.sciencedirect.com
    Development of potent dimeric inhibitors of GAS41 YEATS domain
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    1. scibot 22 Jul 2021
      CRL-5803

      DOI: 10.1016/j.chembiol.2021.06.010

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    sciencedirect.com/science/article/pii/S2451945621003093
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    Systematic analysis of SARS-CoV-2 infection of an ACE2-negative human airway cell
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      CRL-5803

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    sciencedirect.com/science/article/pii/S2211124721007622
  172. Jun 2021
  173. elifesciences.org elifesciences.org
    A non-genetic, cell cycle-dependent mechanism of platinum resistance in lung adenocarcinoma
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      RRID:CVCL_0060

      DOI: 10.7554/eLife.65234

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    elifesciences.org/articles/65234
  174. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RAL GTPases mediate EGFR-driven intestinal stem cell proliferation and tumourigenesis
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      RRID:CVCL_0060

      DOI: 10.7554/eLife.63807

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  175. www.tandfonline.com www.tandfonline.com
    MicroRNA-320a-containing exosomes from human umbilical cord mesenchymal stem cells curtail proliferation and metastasis in lung cancer by binding to SOX4
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      RRID:CVCL_0060

      DOI: 10.1080/10799893.2021.1918166

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  176. May 2021
  177. www.sciencedirect.com www.sciencedirect.com
    PD-L1 recruits phospholipase C and enhances tumorigenicity of lung tumors harboring mutant forms of EGFR
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      RRID:CVCL_0060

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    3D Culture Models with CRISPR Screens Reveal Hyperactive NRF2 as a Prerequisite for Spheroid Formation via Regulation of Proliferation and Ferroptosis
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      RRID:CVCL_0060

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  179. www.sciencedirect.com www.sciencedirect.com
    Asparagine couples mitochondrial respiration to ATF4 activity and tumor growth
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      RRID:CVCL_0060

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  180. Apr 2021
  181. www.sciencedirect.com www.sciencedirect.com
    Non-canonical Glutamate-Cysteine Ligase Activity Protects against Ferroptosis
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      RRID:CVCL_0060

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  182. link.springer.com link.springer.com
    Glutamine deficiency promotes stemness and chemoresistance in tumor cells through DRP1-induced mitochondrial fragmentation
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      RRID:CVCL_0060

      DOI: 10.1007/s00018-021-03818-6

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    Identification of Small-Molecule Activators of the Ubiquitin Ligase E6AP/UBE3A and Angelman Syndrome-Derived E6AP/UBE3A Variants
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      CRL-5803

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  184. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A circular network of coregulated sphingolipids dictates lung cancer growth and progression
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      RRID:CVCL_0060

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  185. www.sciencedirect.com www.sciencedirect.com
    Cancer cells escape autophagy inhibition via NRF2-induced macropinocytosis
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      RRID:CVCL_0060

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  186. www.sciencedirect.com www.sciencedirect.com
    A selective p53 activator and anticancer agent to improve colorectal cancer therapy
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      CRL-5803

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  187. www.sciencedirect.com www.sciencedirect.com
    mTORC1 promotes cell growth via m6A-dependent mRNA degradation
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      RRID:CVCL_0060

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  188. Mar 2021
  189. www.sciencedirect.com www.sciencedirect.com
    Adhesion strength and contractility enable metastatic cells to become adurotactic
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    1. scibot 11 Mar 2021
      ATCC CRL-5803

      DOI: 10.1016/j.celrep.2021.108816

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  190. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Characterization of SALL2 Gene Isoforms and Targets Across Cell Types Reveals Highly Conserved Networks
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      RRID:CVCL_0060

      DOI: 10.3389/fgene.2021.613808

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  191. academic.oup.com academic.oup.com
    Circular RNA hsa_circ_0102231 sponges miR-145 to promote non-small cell lung cancer cell proliferation by up-regulating the expression of RBBP4
    1
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      NCI-H1299

      DOI: 10.1093/jb/mvaa093

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  192. www.sciencedirect.com www.sciencedirect.com
    MMB-FOXM1-driven premature mitosis is required for CHK1 inhibitor sensitivity
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      DOI: 10.1016/j.celrep.2021.108808

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  193. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transketolase regulates sensitivity to APR-246 in p53-null cells independently of oxidative stress modulation
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      DOI: 10.1038/s41598-021-83979-3

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  194. Feb 2021
  195. cancerres.aacrjournals.org cancerres.aacrjournals.org
    3D Functional Genomics Screens Identify CREBBP as a Targetable Driver in Aggressive Triple-Negative Breast Cancer
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  196. Jan 2021
  197. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CLINICALLY RELEVANT CELL CULTURE MODELS AND THEIR SIGNIFICANCE IN ISOLATION, PATHOGENESIS, VACCINE DEVELOPMENT, REPURPOSING AND SCREENING OF NEW DRUGS FOR SARS-COV-2: A SYSTEMATIC REVIEW
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  198. www.sciencedirect.com www.sciencedirect.com
    Proteome-wide identification of NEDD8 modification sites reveals distinct proteomes for canonical and atypical NEDDylation
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  199. www.frontiersin.org www.frontiersin.org
    A Potent and Selective Dual Inhibitor of AXL and MERTK Possesses Both Immunomodulatory and Tumor-Targeted Activity
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      DOI: 10.3389/fonc.2020.598477

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  200. www.sciencedirect.com www.sciencedirect.com
    Increased demand for NAD+ relative to ATP drives aerobic glycolysis
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  201. Oct 2020
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    The mTORC1/S6K/PDCD4/eIF4A Axis Determines Outcome of Mitotic Arrest
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  203. Sep 2020
  204. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    HSPA2 Chaperone Contributes to the Maintenance of Epithelial Phenotype of Human Bronchial Epithelial Cells but Has Non-Essential Role in Supporting Malignant Features of Non-Small Cell Lung Carcinoma, MCF7, and HeLa Cancer Cells
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  205. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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  206. www.sciencedirect.com www.sciencedirect.com
    FBXW7 Confers Radiation Survival by Targeting p53 for Degradation
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      RRID:CVCL_0060

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  207. learn.dcollege.net learn.dcollege.net
    SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor
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      RRID:CVCL_0060

      DOI: 10.1016/j.cell.2020.02.052

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  208. cancerres.aacrjournals.org cancerres.aacrjournals.org
    Oxygen-enhanced optoacoustic tomography reveals the effectiveness of targeting heme and oxidative phosphorylation at normalizing tumor vascular oxygenation
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      RRID:CVCL_0060

      DOI: 10.1158/0008-5472.CAN-19-3247

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  209. elifesciences.org elifesciences.org
    Analysis of pulsed cisplatin signalling dynamics identifies effectors of resistance in lung adenocarcinoma
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      RRID:CVCL_0060

      DOI: 10.7554/eLife.53367

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  210. www.sciencedirect.com www.sciencedirect.com
    The Negative Cross-Talk between SAG/RBX2/ROC2 and APC/C E3 Ligases in Regulation of Cell Cycle Progression and Drug Resistance
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      H1299

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  211. academic.oup.com academic.oup.com
    The effects of 20-kDa human placental GH in male and female GH deficient mice: an improved human GH?
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      RRID:CVCL_0060

      DOI: 10.1210/endocr/bqaa097

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    academic.oup.com/endo/article/161/8/bqaa097/5859553
  212. www.sciencedirect.com www.sciencedirect.com
    Chromosome 3q26 Gain Is an Early Event Driving Coordinated Overexpression of the PRKCI, SOX2, and ECT2 Oncogenes in Lung Squamous Cell Carcinoma
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    1. scibot 06 Sep 2020
      RRID:CVCL_0060

      DOI: 10.1016/j.celrep.2019.12.071

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  213. www.sciencedirect.com www.sciencedirect.com
    Nuclear TARBP2 Drives Oncogenic Dysregulation of RNA Splicing and Decay
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  214. www.mdpi.com www.mdpi.com
    Various Anti-HSPA2 Antibodies Yield Different Results in Studies on Cancer-Related Functions of Heat Shock Protein A2
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      NCI-H1299

      DOI: 10.3390/ijms21124296

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    mdpi.com/1422-0067/21/12/4296
  215. www.nature.com www.nature.com
    Combination of CHEK1/2 inhibition and ionizing radiation results in abscopal tumor response through increased micronuclei formation
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      RRID:CVCL_0060

      DOI: 10.1038/s41388-020-1300-x

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    nature.com/articles/s41388-020-1300-x
  216. onlinelibrary.wiley.com onlinelibrary.wiley.com
    The transcription factor FLI1 promotes cancer progression by affecting cell cycle regulation
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      RRID:CVCL_0060

      DOI: 10.1002/ijc.32831

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    onlinelibrary.wiley.com/doi/10.1002/ijc.32831
  217. Jan 2020
  218. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cysteine dioxygenase 1 is a metabolic liability for non-small cell lung cancer
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    1. scibot 13 Jan 2020
      RRID:CVCL_0060

      DOI: 10.7554/eLife.45572

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    ncbi.nlm.nih.gov/pmc/articles/PMC6584702/
  219. www.sciencedirect.com www.sciencedirect.com
    GRWD1 promotes cell proliferation and migration in non-small cell lung cancer by activating the Notch pathway
    1
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      CVCL_0060

      DOI: 10.1016/j.yexcr.2019.111806

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    sciencedirect.com/science/article/pii/S0014482719306949
  220. www.sciencedirect.com www.sciencedirect.com
    Transsulfuration Activity Can Support Cell Growth upon Extracellular Cysteine Limitation
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      RRID:CVCL_0060

      DOI: 10.1016/j.cmet.2019.09.009

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    Activation of Oxidative Stress Response in Cancer Generates a Druggable Dependency on Exogenous Non-essential Amino Acids
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      RRID:CVCL_0060

      DOI: 10.1016/j.cmet.2019.11.012

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    sciencedirect.com/science/article/pii/S1550413119306199
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    BACH1 Stabilization by Antioxidants Stimulates Lung Cancer Metastasis
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      CVCL_0060

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  223. www.sciencedirect.com www.sciencedirect.com
    VISAGE Reveals a Targetable Mitotic Spindle Vulnerability in Cancer Cells
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      RRID:CVCL_0060

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    γ-6-Phosphogluconolactone, a Byproduct of the Oxidative Pentose Phosphate Pathway, Contributes to AMPK Activation through Inhibition of PP2A
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      RRID:CVCL_0060

      DOI: 10.1016/j.molcel.2019.09.007

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    SFRPs Are Biphasic Modulators of Wnt-Signaling-Elicited Cancer Stem Cell Properties beyond Extracellular Control
    1
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      RRID:CVCL_0060

      DOI: 10.1016/j.celrep.2019.07.023

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  226. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Radioresistance of KRAS/TP53‐Mutated Lung Cancer can be overcome by Radiation Dose Escalation or EGFR Tyrosine Kinase Inhibition In Vivo
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      RRID:CVCL_0060

      DOI: 10.1002/ijc.32598

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  227. cancerres.aacrjournals.org cancerres.aacrjournals.org
    Elevated Heme Synthesis and Uptake Underpin Intensified Oxidative Metabolism and Tumorigenic Functions in Non–Small Cell Lung Cancer Cells
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      RRID:CVCL_0060

      DOI: 10.1158/0008-5472.CAN-18-2156

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  228. www.sciencedirect.com www.sciencedirect.com
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      RRID:CVCL_0060

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  230. www.sciencedirect.com www.sciencedirect.com
    Deubiquitinases Maintain Protein Homeostasis and Survival of Cancer Cells upon Glutathione Depletion
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      DOI: 10.1016/j.cmet.2019.01.020

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    MDM2 Integrates Cellular Respiration and Apoptotic Signaling through NDUFS1 and the Mitochondrial Network
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  232. Apr 2019
  233. elifesciences.org elifesciences.org
    Palmitoylated SCP1 is targeted to the plasma membrane and negatively regulates angiogenesis
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      CVCL-0060

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  234. elifesciences.org elifesciences.org
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    elifesciences.org/articles/22323
  235. Nov 2018
  236. www.sciencedirect.com www.sciencedirect.com
    Human Rad52 Promotes XPG-Mediated R-loop Processing to Initiate Transcription-Associated Homologous Recombination Repair
    1
    1. scibot 05 Nov 2018
      CRL-5803

      Curator: @Jmenke

      Resource used:

      (ATCC Cat# CRL-5803, RRID:CVCL_0060)

      SciCrunch record: RRID:CVCL_0060

      Alternate resolvers: SciCrunch xml N2T identifiers.org

      What is this?

      RRID:CVCL_0060 RRIDCUR:Missing
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    URL

    sciencedirect.com/science/article/pii/S0092867418311176
  237. www.sciencedirect.com www.sciencedirect.com
    Cytosolic Aspartate Availability Determines Cell Survival When Glutamine Is Limiting
    1
    1. scibot 05 Nov 2018
      CRL-5803

      Curator: @Jmenke

      Resource used:

      (ATCC Cat# CRL-5803, RRID:CVCL_0060)

      SciCrunch record: RRID:CVCL_0060

      Alternate resolvers: SciCrunch xml N2T identifiers.org

      What is this?

      RRID:CVCL_0060 RRIDCUR:Missing
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    URL

    sciencedirect.com/science/article/pii/S1550413118304649
  238. www.sciencedirect.com www.sciencedirect.com
    Therapeutic Ablation of Gain-of-Function Mutant p53 in Colorectal Cancer Inhibits Stat3-Mediated Tumor Growth and Invasion
    1
    1. scibot 05 Nov 2018
      CRL-5803

      Curator: @Jmenke

      Resource used:

      (ATCC Cat# CRL-5803, RRID:CVCL_0060)

      SciCrunch record: RRID:CVCL_0060

      Alternate resolvers: SciCrunch xml N2T identifiers.org

      What is this?

      RRID:CVCL_0060 RRIDCUR:Missing
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    URL

    sciencedirect.com/science/article/pii/S153561081830309X
  239. www.sciencedirect.com www.sciencedirect.com
    Dependence on the Pyrimidine Biosynthetic Enzyme DHODH Is a Synthetic Lethal Vulnerability in Mutant KRAS-Driven Cancers
    1
    1. scibot 05 Nov 2018
      CRL-5803

      Curator: @Jmenke

      Resource used:

      (ATCC Cat# CRL-5803, RRID:CVCL_0060)

      SciCrunch record: RRID:CVCL_0060

      Alternate resolvers: SciCrunch xml N2T identifiers.org

      What is this?

      RRID:CVCL_0060 RRIDCUR:Missing
    Visit annotations in context

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    URL

    sciencedirect.com/science/article/pii/S2451945618301077