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A GPX1-OSBPL8 axis mediates noncanonical in vivo ferroptosis and cancer growth suppression

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1. scibot 20 Feb 2026
  
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  ATCCCRL-1619
  
  DOI: 10.1016/j.cell.2026.01.009
  
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sciencedirect.com/science/article/pii/S0092867426000565
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The transcriptional repressor Fli1 inhibits proteostasis during nutrient stress to limit NK cell persistence in solid tumors

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1. scibot 19 Feb 2026
  
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  ATCCCat#: CRL-1619
  
  DOI: 10.1016/j.immuni.2026.01.017
  
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sciencedirect.com/science/article/pii/S107476132600035X
Feb 2026
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Hypoxia restores the acidosis-induced inhibition of cancer cell dissemination

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1. scibot 13 Feb 2026
  
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  ATCCCat # CRL-1619
  
  DOI: 10.1016/j.celrep.2026.116970
  
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sciencedirect.com/science/article/pii/S2211124726000483
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BPS Publications

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1. scibot 10 Feb 2026
  
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  RRID:CVCL_0132
  
  DOI: 10.1111/bph.70357
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.70357
journals.plos.org journals.plos.org

The lipid-metabolic enzyme HSD17B12 drives lysosomal degradation of PD-L1 potentiating anti-tumor immunity in a mouse model

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1. scibot 03 Feb 2026
  
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  RRID: CVCL_0132
  
  DOI: 10.1371/journal.pbio.3003603
  
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journals.plos.org/plosbiology/article
Jan 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

ATAD2 drives melanoma growth and progression and inhibits ferroptosis

1
1. scibot 31 Jan 2026
  
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  CRL-1619
  
  DOI: 10.1038/s44319-025-00660-w
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12852765/
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Extracellular vesicles released from melanoma cells constitutively expressing MHC class II promote immune evasion and cancer progression

1
1. scibot 29 Jan 2026
  
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  RRID:CVCL_0132
  
  DOI: 10.1111/febs.70414
  
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febs.onlinelibrary.wiley.com/doi/10.1111/febs.70414
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Systematic annotation of orphan RNAs reveals blood-accessible molecular barcodes of cancer identity and cancer-emergent oncogenic drivers

1
1. scibot 27 Jan 2026
  
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  ATCCCat#CRL-1619
  
  DOI: 10.1016/j.xcrm.2025.102577
  
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sciencedirect.com/science/article/pii/S2666379125006500
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CRISPR screens in the context of immune selection identify CHD1 and MAP3K7 as mediators of cancer immunotherapy resistance

1
1. scibot 22 Jan 2026
  
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  RRID: CVCL_0132
  
  DOI: 10.1016/j.xcrm.2025.102565
  
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sciencedirect.com/science/article/pii/S266637912500638X
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NF1 Loss Remodels Tumor Niches for Immune Evasion

1
1. scibot 16 Jan 2026
  
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  RRID:CVCL_0132
  
  DOI: 10.64898/2026.01.11.698818
  
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biorxiv.org/content/10.64898/2026.01.11.698818v1
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Unveiling the Anticancer Potential of Verbascum aydogdui: Isolation, Characterization, and In Vitro Studies

1
1. scibot 15 Jan 2026
  
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  RRID:CVCL_0132
  
  DOI: 10.1002/cbdv.202503376
  
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onlinelibrary.wiley.com/doi/10.1002/cbdv.202503376
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Ubiquitination-directed cytosolic DNA degradation governs cGAS-STING-mediated immune response to DNA damage

1
1. scibot 09 Jan 2026
  
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  ATCCCRL-1619
  
  DOI: 10.1016/j.ccell.2025.12.013
  
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sciencedirect.com/science/article/pii/S1535610825005471
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Theranostic Nonstoichiometric, Multivalent Bismuth (Bi)-Based Nanospheres for Selective Spontaneous Melanoma Treatment

1
1. scibot 06 Jan 2026
  
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  RRID:CVCL_0132
  
  DOI: 10.1021/acsami.5c20966
  
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pubs.acs.org/doi/full/10.1021/acsami.5c20966
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5-HT reuptake blockade induces pyroptosis in BRAFV600E-mutated melanomas via remodeling histone serotonylation

1
1. scibot 05 Jan 2026
  
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  ATCCCRL-1619
  
  DOI: 10.1016/j.xcrm.2025.102537
  
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sciencedirect.com/science/article/pii/S266637912500610X
Dec 2025
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Paeoniflorin Promotes Therapeutic Senescence in Melanoma through Endoplasmic Reticulum Stress and the Calpain1/ERK5/p27 Axis

1
1. scibot 25 Dec 2025
  
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  RRID:CVCL_0132
  
  DOI: 10.1016/j.phymed.2025.157730
  
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sciencedirect.com/science/article/pii/S0944711325013649
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Engineered antibodies that stabilize drug-modified KRASG12C neoantigens enable selective and potent cross-HLA immunotherapy

1
1. scibot 23 Dec 2025
  
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  CRL-1619
  
  DOI: 10.1038/s41467-025-66132-w
  
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nature.com/articles/s41467-025-66132-w
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Comprehensive analysis based on spatial domains identifies CD44 as a potential target of puerarin

1
1. scibot 20 Dec 2025
  
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  RRID:CVCL_0132
  
  DOI: 10.1007/s00432-025-06389-2
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12712269/
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Machine learning-based development of a cytotoxicity prediction model for NK cell therapy in cancers

1
1. scibot 19 Dec 2025
  
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  RRID:CVCL_0132
  
  DOI: 10.1007/s13402-025-01113-1
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12698772/
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Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

1
1. scibot 11 Dec 2025
  
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  RRID:CVCL_0132
  
  DOI: 10.1002/1878-0261.70169
  
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febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.70169
Nov 2025
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UMP functions as an endogenous regulator of NR4A1 to control gastric cancer progression

1
1. scibot 22 Nov 2025
  
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  ATCCCRL-1619
  
  DOI: 10.1016/j.molcel.2025.10.030
  
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sciencedirect.com/science/article/pii/S1097276525008913
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An immunometabolic prodrug strategy overcomes DHODH inhibitor resistance in refractory melanoma

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1. scibot 18 Nov 2025
  
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  RRID:CVCL_0132
  
  DOI: 10.1186/s13046-025-03566-6
  
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link.springer.com/article/10.1186/s13046-025-03566-6
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KLF5 enables dichotomous lineage programs in pancreatic cancer via the AAA+ ATPase coactivators RUVBL1 and RUVBL2

1
1. scibot 18 Nov 2025
  
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  RRID:CVCL_0132
  
  DOI: 10.1038/s41467-025-66007-0
  
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nature.com/articles/s41467-025-66007-0
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Cortical organoid-derived models of the melanoma brain metastatic niche enable prioritization of cancer-targeting drugs

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1. scibot 15 Nov 2025
  
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  RRID:CVCL_0132
  
  DOI: 10.1016/j.crmeth.2025.101236
  
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sciencedirect.com/science/article/pii/S2667237525002723
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Developing a therapeutic elastase that stimulates anti-tumor immunity by selectively killing cancer cells

1
1. scibot 13 Nov 2025
  
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  ATCCCat# CRL-1619
  
  DOI: 10.1016/j.xcrm.2025.102446
  
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sciencedirect.com/science/article/pii/S2666379125005191
54.241.53.176 54.241.53.176

2025.11.06.686987v1.full-html.html

1
1. scibot 13 Nov 2025
  
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  CVCL_0132
  
  DOI: 10.1101/2025.11.06.686987
  
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54.241.53.176/5f95eab3fd5667f2f2f747297eac3c06fff8097d/2025.11.06.686987v1.full-html.html
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CDK12 inhibition reveals melanoma dependence on the RUNX1/CBFβ complex for genomic stability

1
1. scibot 06 Nov 2025
  
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  CVCL_0132
  
  DOI: 10.1016/j.celrep.2025.116495
  
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sciencedirect.com/science/article/pii/S2211124725012665
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The lipid droplet protein DHRS3 is a regulator of melanoma cell state

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1. scibot 01 Nov 2025
  
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  RRID:CVCL_0132
  
  DOI: 10.1111/pcmr.13208
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12244328/
Oct 2025
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High-throughput combination screening of Pidnarulex and other G-quadruplex ligands in multi-cell type tumor spheroids

1
1. scibot 29 Oct 2025
  
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  RRID:CVCL_0132
  
  DOI: 10.1016/j.slasd.2025.100284
  
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sciencedirect.com/science/article/pii/S2472555225000772
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Development of retinoid nuclear receptor pathway antagonists through targeting aldehyde dehydrogenase 1A3

1
1. scibot 28 Oct 2025
  
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  RRID:CVCL_0132
  
  DOI: 10.1016/j.isci.2025.113675
  
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sciencedirect.com/science/article/pii/S2589004225019364
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Cannabidivarin directly targets the immunosuppressive activity of regulatory myeloid cells in tumors

1
1. scibot 28 Oct 2025
  
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  RRID:CVCL_0132
  
  DOI: 10.1016/j.biopha.2025.118697
  
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sciencedirect.com/science/article/pii/S0753332225008911
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Systematic design of DMBT1-derived peptides correlating physicochemical properties and sequence motifs with siRNA delivery and efficacy in cancer therapy

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1. scibot 23 Oct 2025
  
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  RRID:CVCL_0132
  
  DOI: 10.1016/j.ebiom.2025.105977
  
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sciencedirect.com/science/article/pii/S2352396425004219
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Optimized arenaviruses with tumor-tropic mutations promote safe anti-tumor efficacy via sustainable immune modulatory properties

1
1. scibot 15 Oct 2025
  
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  ATCCCRL-1619
  
  DOI: 10.1016/j.xcrm.2025.102411
  
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A cancer-specific antigen drives histone acetylation by stabilizing the acetyltransferases

1
1. scibot 08 Oct 2025
  
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  RRID:CVCL_0132
  
  DOI: 10.1016/j.celrep.2025.116408
  
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sciencedirect.com/science/article/pii/S2211124725011799
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Inhibiting Cyclin-Dependent Kinase 13-Mediated Nuclear Ubiquitous Casein Kinase and Cyclin-Dependent Kinase Substrate 1 Phosphorylation Facilitates Oxidative Stress-Induced Apoptosis in Melanoma

1
1. scibot 07 Oct 2025
  
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  RRID:CVCL_0132
  
  DOI: 10.1002/mc.70040
  
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onlinelibrary.wiley.com/doi/10.1002/mc.70040
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Laeverin is Cell-Surface Target for Liquid-Phase Metastasizing Cancer Cells

1
1. scibot 07 Oct 2025
  
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  RRID:CVCL_0132
  
  DOI: 10.1002/advs.202511349
  
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advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202511349
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

CDH3-AS1 antisense RNA enhances P-cadherin translation and acts as a tumor suppressor in melanoma

1
1. scibot 05 Oct 2025
  
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  ATCCCRL-1619
  
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USP9X is a mechanosensitive deubiquitinase that controls tumor cell invasiveness and drug response through YAP stabilization

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Vorapaxar enhanced mitochondria-associated ferroptosis primes cancer immunotherapy via targeting FOXO1/HMOX1 axis

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RHOJ enhances adhesion and proliferation capabilities and suppresses apoptosis of melanoma cells by activating the Rap1 signaling pathway

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Phase Ib Study of Pembrolizumab in Combination with Intratumoral Injection of Clostridium novyi-NT in Patients with Advanced Solid Tumors

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mTOR inhibition reprograms cellular lipid homeostasis by inducing alternative lipid uptake and promoting cholesterol transport

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RAD23B acquires a copper metalloadaptor function in amphibian-to-reptile evolution to increase metabolism and regulate genomic integrity

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PKN2 is a dependency of the mesenchymal-like cancer cell state

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NF1 Loss Promotes EGFR Activation and Confers Sensitivity to EGFR Inhibition in NF1 Mutant Melanoma

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Endogenous YAP/TAZ partitioning in TEAD condensates orchestrates the Hippo response

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Cytotoxicity of activator expression in CRISPR-based transcriptional activation systems

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DFFB suppresses interferon to enable cancer persister cell regrowth

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Targeting lipid scrambling potentiates ferroptosis and triggers tumor immune rejection

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Targeting lipid scrambling potentiates ferroptosis and triggers tumor immune rejection

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Preclinical Evaluation of DB-1419, a Novel Bifunctional and Bispecific Anti–B7-H3 × PD-L1 Antibody–Drug Conjugate

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A Nanovial-Based Platform for Functional Discovery of Antigen-Reactive TCRs from Unconventional T Cells

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Tissue-dependent mechanosensing by cells derived from human tumors

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A pan-KRAS inhibitor and its derived degrader elicit multifaceted anti-tumor efficacy in KRAS-driven cancers

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Pathway metabolite ratios reveal distinctive glutamine metabolism in a subset of proliferating cells

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Investigating the relationship Between AMBRA1 and Cell Proliferation in Melanoma

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Secretogranin 2 binds LILRB4 resulting in immunosuppression

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Direct transdifferentiation of tumorigenic melanoma cells induces tumor cell reversion

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IgSF11–RAP1 signaling promotes cell migration and invasion of cutaneous melanoma

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PHGDH Induction by MAPK is Essential for Melanoma Formation and Creates an Actionable Metabolic Vulnerability

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CDC42-effector interaction inhibitors alter patterns of vessel arborization in skin and tumors in vivo

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Salmonella hijacks a host glucose transporter for intravacuolar proliferation

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A Rac-specific competitive inhibitor of guanine nucleotide binding reduces metastasis in triple-negative breast cancer

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Identification of UBE3C as an E3 ubiquitin ligase for mutant BRAF

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FEBS Press

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Ribosomal RNA transcription regulates splicing through ribosomal protein RPL22

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Targeting Oncofoetal Chondroitin Sulphate Allows Identification of Tumour‐Derived Extracellular Vesicles

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A phase 1/2 clinical trial of invariant natural killer T cell therapy in moderate-severe acute respiratory distress syndrome

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Single-Cell Transcriptomic Landscape Deciphers Intratumoral Heterogeneity and Subtypes of Acral and Mucosal Melanomas

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PDF-html.html

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ltaf023-html.html

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Cancer selective cell death induction by a bivalent CK2 inhibitor targeting the ATP site and the allosteric αD pocket

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FEBS Press

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EZH2 loss during metabolic stress drives restoration of MHC class I machinery in melanoma

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Potentiating T cell tumor targeting using a combination of TCR with a Siglec-7 based CSR

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  CVCL_0132
  
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Derepressing nuclear pyruvate dehydrogenase induces therapeutic cancer cell reprogramming

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Dose-dependent induction of epithelial-mesenchymal transition in 3D melanoma models by non-thermal plasma treatment

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Human CSPG4-targeting CAR-macrophages inhibit melanoma growth

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Machine-learning-assisted universal protein activation in living mice

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Serotonin transporter inhibits antitumor immunity through regulating the intratumoral serotonin axis

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FEBS Press

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Small Molecule Functional Converter of B-Cell Lymphoma-2 (Bcl-2) Suppresses Breast Cancer Lung Metastasis

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Generation of T cell responses against broad KRAS hotspot neoantigens for cell therapy or TCR discovery

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Tumorigenesis Driven by BRAFV600E Requires Secondary Mutations That Overcome Its Feedback Inhibition of RAC1 and Migration

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Stromal lipid species dictate melanoma metastasis and tropism

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Liposome-Polymer Nanoparticles Loaded with Copper Diethyldithiocarbamate and 6-Bromo-Indirubin-3′-Oxime Enable the Treatment of Refractive Melanoma

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LncRNA SLNCR phenocopies the E2F1 DNA binding site to promote melanoma progression

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Enhancing the Efficacy of CAR-T Cell Production Using BX795 and Rosuvastatin in a Serum-Free Medium

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Protocol to profile tumor and microenvironment from ovarian cancer patient samples and evaluate cell-based therapy using in vitro killing assays

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SEMA3G-NRP1 Signaling Functions as an Immune Checkpoint that Enables Tumor Immune Evasion by Impairing T Cell Cytotoxicity

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Library-based single-cell analysis of CAR signaling reveals drivers of in vivo persistence

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VAX014 Activates Tumor-Intrinsic STING and RIG-I to Promote the Development of Antitumor Immunity

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Pan-KRAS Inhibitors BI-2493 and BI-2865 Display Potent Antitumor Activity in Tumors with KRAS Wild-type Allele Amplification

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Augmenting CAR T Cell Functions with LIGHT

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Homeostatic regulation of nucleoporins is a central driver of nuclear pore biogenesis

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Lactylation of LSD1 is an acquired epigenetic vulnerability of BRAFi/MEKi-resistant melanoma

1
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Antagonistic roles for MITF and TFE3 in melanoma plasticity

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Translation dysregulation in cancer as a source for targetable antigens

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Interaction with tumor cell spheroids induces suppression in primary human cytotoxic T cells

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  DOI: 10.1101/2025.03.18.643973
  
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Simultaneous CRISPR screening and spatial transcriptomics reveal intracellular, intercellular, and functional transcriptional circuits

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Overexpression of LMOD1 induces oxidative stress and enhances cell apoptosis of melanoma through the RIG-I like receptor pathway

1
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Recognition of MR1-antigen complexes by TCR Vγ9Vδ2

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  DOI: 10.3389/fimmu.2025.1519128
  
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Realigned transsulfuration drives BRAF-V600E-targeted therapy resistance in melanoma

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Lymph node macrophages drive immune tolerance and resistance to cancer therapy by induction of the immune-regulatory cytokine IL-33

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  DOI: 10.1016/j.ccell.2025.02.017
  
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The NF1 tumor suppressor regulates PD-L1 and immune evasion in melanoma

1
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  RRID:CVCL_0132
  
  DOI: 10.1016/j.celrep.2025.115365
  
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An epitope-directed mRNA vaccine inhibits tumor metastasis through the blockade of MICA/B α1/2 shedding

1
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  ATCCCat# CRL-1619
  
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MR1 gene and protein expression are enhanced by inhibition of the extracellular signal-regulated kinase ERK

1
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  DOI: 10.1158/2326-6066.CIR-24-0110
  
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The E3 ubiquitin ligase FBXO38 maintains the antitumor function of natural killer cells by sustaining IL-15R signaling

1
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  RRID:CVCL_0132
  
  DOI: 10.1158/2326-6066.CIR-23-1061
  
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Targeting Tumor-Associated Sialic Acids using Chimeric Switch Receptors based on Siglec-9 Enhances the Antitumor Efficacy of Engineered T Cells

1
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  RRID:CVCL_0132
  
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ILT2 and ILT4 drive myeloid suppression via both overlapping and distinct mechanisms

1
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  RRID:CVCL_0132
  
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The IAP antagonist tolinapant enhances the anti-tumor activity of cell therapies

1
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  RRID:CVCL_0132
  
  DOI: 10.1016/j.ejphar.2025.177400
  
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can-24-2223-html.html

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52.53.155.43/752d85b7b45cbe249ff1ba5f1b04c7c2ca434b68/can-24-2223-html.html
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CDK2 activity crosstalk on the ERK kinase translocation reporter can be resolved computationally

1
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  DOI: 10.1016/j.cels.2024.12.003
  
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RECQL4 affects MHC class II‐mediated signalling and favours an immune‐evasive signature that limits response to immune checkpoint inhibitor therapy in patients with malignant melanoma

1
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  DOI: 10.1002/ctm2.70094
  
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Dec 2024
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PDF-html.html

1
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  CRL-1619
  
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The carbonyl nucleobase adduct M3Ade is a potent antigen for adaptive polyclonal MR1-restricted T cells

1
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  ATCCCRL-1619
  
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Transcriptional and functional regulation of cell cycle and UV response by PPARβ in human skin epidermal cells

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  RRID:CVCL_0132
  
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Nucleo-cytosolic acetyl-CoA drives tumor immune evasion by regulating PD-L1 in melanoma

1
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  CRL-1619
  
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ACSS1-dependent acetate utilization rewires mitochondrial metabolism to support AML and melanoma tumor growth and metastasis

1
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  DOI: 10.1016/j.celrep.2024.114988
  
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Silica Nanoparticles Decorated with Ceria Quantum Dots Modulate Intra- and Extracellular Reactive Oxygen Species Formation and Selectively Reduce Human A375 Melanoma Cell Proliferation

2
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  DOI: 10.1021/acsami.4c11483
  
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  DOI: 10.1021/acsami.4c11483
  
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A peptide encoded by LINC00944 suppresses the growth of melanoma cells by diminishing EP400-MYC interaction

1
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  RRID:CVCL_0132
  
  DOI: 10.1016/j.bcp.2024.116652
  
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C19MC Drives Nucleolar Invasion of Mitochondria and Meiotic Nuclear Division in Human Cancers

1
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PRDX6 dictates ferroptosis sensitivity by directing cellular selenium utilization

1
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  CRL-1619
  
  DOI: 10.1016/j.molcel.2024.10.028
  
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Itaconate transporter SLC13A3 impairs tumor immunity via endowing ferroptosis resistance

1
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  CRL-1619
  
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Dysregulation of R-loop homeostasis shapes the immunosuppressive microenvironment and induces malignant progression in melanoma

1
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  DOI: 10.1007/s10495-024-02039-z
  
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link.springer.com/article/10.1007/s10495-024-02039-z
Oct 2024
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RAF-Mutant Melanomas Differentially Depend on ERK2 Over ERK1 to Support Aberrant MAPK Pathway Activation and Cell Proliferation

1
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aacrjournals.org/mcr/article/19/6/1063/672883/RAF-Mutant-Melanomas-Differentially-Depend-on-ERK2
Sep 2024
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Precision Oncology and Systemic Targeted Therapy in Pseudomyxoma Peritonei

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Aged fibroblast-derived extracellular vesicles promote angiogenesis in melanoma

1
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  CRL-1619
  
  DOI: 10.1016/j.celrep.2024.114721
  
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Aug 2024
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Targeting MYC effector functions in pancreatic cancer by inhibiting the ATPase RUVBL1/2

1
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  DOI: 10.1136/gutjnl-2023-331519
  
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Dysfunctional BTN3A together with deregulated immune checkpoints and type I/II IFN dictate defective interplay between pDCs and γδ T cells in melanoma patients, which impacts clinical outcomes

1
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p300 KAT Regulates SOX10 Stability and Function in Human Melanoma

3
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  RRID:CVCL_0132
  
  DOI: 10.1158/2767-9764.CRC-24-0124
  
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  DOI: 10.1158/2767-9764.CRC-24-0124
  
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Medical Gas Plasma Technology Combines with Antimelanoma Therapies and Promotes Immune-Checkpoint Therapy Responses

1
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  ATCC: CRL‐1619
  
  DOI: 10.1002/advs.202303183
  
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A Comparative Survey of Anti-Melanoma and Anti-Inflammatory Potential of Usnic Acid Enantiomers—A Comprehensive In Vitro Approach

1
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  CRL-1619
  
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Jul 2024
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NAMPT-targeting PROTAC and nicotinic acid co-administration elicit safe and robust anti-tumor efficacy in NAPRT-deficient pan-cancers

1
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  Cat#CRL-1619
  
  DOI: 10.1016/j.chembiol.2024.05.007
  
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IFN-γ-responsiveness of lymphatic endothelial cells inhibits melanoma lymphatic dissemination via AMPK-mediated metabolic control

1
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  RRID:CVCL_0132
  
  DOI: 10.1016/j.bbadis.2024.167314
  
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Target fishing and mechanistic insights of the natural anticancer drug candidate chlorogenic acid

1
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  CRL-1619
  
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FEBS Press

1
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  RRID:CVCL_0132
  
  DOI: 10.1002/1873-3468.14960
  
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DHODH inhibition enhances the efficacy of immune checkpoint blockade by increasing cancer cell antigen presentation

1
1. scibot 12 Jul 2024
  
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  CRL-1619
  
  DOI: 10.7554/eLife.87292
  
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Jun 2024
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FEBS Press

1
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  CVCL_0132
  
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NRAS mutant dictates AHCYL1-governed ER calcium homeostasis for melanoma tumor growth

1
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  RRID: CVCL_0132
  
  DOI: 10.1158/1541-7786.MCR-23-0445
  
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Lipid-encapsulated mRNAs encoding complex fusion proteins potentiate anti-tumor immune responses

1
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  RRID:CVCL_0132
  
  DOI: 10.1158/0008-5472.CAN-23-2875
  
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Pathway metabolite ratios reveal distinctive glutamine metabolism in a subset of proliferating cells

2
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  RRID:CVCL_0132
  
  DOI: 10.1101/2024.02.18.580900
  
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Latent-transforming growth factor β-binding protein 1/Transforming growth factor β1 complex drives antitumoral effects upon ERK5 targeting in melanoma

1
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Apr 2024
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HDAC10 inhibition represses melanoma cell growth and BRAF inhibitor resistance via upregulating SPARC expression

1
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  RRID:CVCL_0132
  
  DOI: 10.1093/narcan/zcae018
  
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IGSF8 is an innate immune checkpoint and cancer immunotherapy target

1
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  Cat# CRL-1619
  
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PRMT1 inhibition activates the interferon pathway to potentiate antitumor immunity and enhance checkpoint blockade efficacy in melanoma

1
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  RRID: CVCL_0132
  
  DOI: 10.1158/0008-5472.CAN-23-1082
  
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Environmentally dependent and independent control of 3D cell shape

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  RRID: CVCL_0132
  
  DOI: 10.1016/j.celrep.2024.114016
  
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PARP1 expression predicts PARP inhibitor sensitivity and correlates with metastatic potential and overall survival in melanoma

1
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  DOI: 10.1002/ijc.34947
  
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Induction of stearoyl-CoA desaturase confers cell density-dependent ferroptosis resistance in melanoma

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  DOI: 10.1002/jcb.30542
  
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Targeting of vulnerabilities of drug-tolerant persisters identified through functional genetics delays tumor relapse

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Discovery of YAP1/TAZ pathway inhibitors through phenotypic screening with potent anti-tumor activity via blockade of Rho-GTPase signaling

1
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  Cat#CRL-1619
  
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Light-mediated intracellular polymerization

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  DOI: 10.1038/s41596-024-00970-8
  
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De novo steroidogenesis in tumor cells drives bone metastasis and osteoclastogenesis

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  ATCCCat# CRL-1619
  
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Multimodal stimulation screens reveal unique and shared genes limiting T cell fitness

3
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  DOI: 10.1016/j.ccell.2024.02.016
  
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  DOI: 10.1016/j.ccell.2024.02.016
  
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  DOI: 10.1016/j.ccell.2024.02.016
  
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Low-dose Decitabine enhances the efficacy of viral cancer vaccines for immunotherapy.

1
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Identification and characterization of a small molecule Bcl-2 Functional Converter

1
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  DOI: 10.1158/2767-9764.CRC-22-0526
  
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A tangible method to assess native ferroptosis suppressor activity

1
1. scibot 27 Feb 2024
  
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  ATCCCRL-1619
  
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First-in-Human Study with preclinical data of BCL-2/BCL-xL Inhibitor Pelcitoclax in Locally Advanced or Metastatic Solid Tumors

1
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  DOI: 10.1158/1078-0432.CCR-23-1525
  
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419-html.html

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Alternative Wnt-signaling axis leads to a break of oncogene-induced senescence

1
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  DOI: 10.1038/s41419-024-06550-8
  
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RhoA activation promotes glucose uptake to elevate proliferation in MAPK inhibitor resistant melanoma cells

1
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HDAC10 blockade upregulates SPARC expression thereby repressing melanoma cell growth and BRAF inhibitor resistance

2
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  RRID:CVCL_0132
  
  DOI: 10.1101/2023.12.05.570182
  
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PHLDA2-mediated phosphatidic acid peroxidation triggers a distinct ferroptotic response during tumor suppression

1
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Subsets of interferon signaling predict response to immune checkpoint blockade in melanoma patients

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Jan 2024
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Translation of non-canonical open reading frames as a cancer cell survival mechanism in childhood medulloblastoma

1
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Tumor cell–intrinsic PD-1 promotes Merkel cell carcinoma growth by activating downstream mTOR-mitochondrial ROS signaling

2
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  DOI: 10.1126/sciadv.adi2012
  
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Discovery of galectin-8 as an LILRB4 ligand driving M-MDSCs defines a class of antibodies to fight solid tumors

1
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  ATCCCat#CRL-1619
  
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Inhibition of CSF-1R and IL-6R prevents conversion of cDC2s into immune incompetent tumor-induced DC3s boosting DC-driven therapy potential

1
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  DOI: 10.1016/j.xcrm.2023.101386
  
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Translation of non-canonical open reading frames as a cancer cell survival mechanism in childhood medulloblastoma

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  DOI: 10.1016/j.molcel.2023.12.003
  
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A TCF4-dependent gene regulatory network confers resistance to immunotherapy in melanoma

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The HLA-II immunopeptidome of SARS-CoV-2

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Sphingolipid paracrine signaling impairs keratinocyte adhesion to promote melanoma invasion

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A Cell Surface-Binding Antibody Atlas Nominates a MUC18-Directed Antibody–Drug Conjugate for Targeting Melanoma

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Acquired and intrinsic resistance to vemurafenib in BRAFV600E-driven melanoma brain metastases

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  DOI: 10.1002/2211-5463.13730
  
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Anti-tumor effect of PD-L1-targeting antagonistic aptamer-ASO delivery system with dual inhibitory function in immunotherapy

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HRS mediates tumor immune evasion by regulating proteostasis-associated interferon pathway activation

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A Thia-Analogous Indirubin N-Glycoside Disrupts Mitochondrial Function and Causes the Death of Human Melanoma and Cutaneous Squamous Cell Carcinoma Cells

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1. scibot 13 Oct 2023
  
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Bioinformatics-based analysis reveals elevated CYTL1 as a potential therapeutic target for BRAF-mutated melanoma

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Selective Inhibition of indoleamine and tryptophan 2,3-dioxygenases: Comparative Study on Kynurenine Pathway in Cell Lines via LC-MS/MS-based Targeted Metabolomics

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Modular pooled discovery of synthetic knockin sequences to program durable cell therapies

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British J Pharmacology - 2023 - Kleszcz-html.html

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Testicular germ cell tumour cells release microRNA-containing extracellular vesicles that induce phenotypic and genotypic changes in cells of the tumour microenvironment

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Methionine oxidation selectively enhances T cell reactivity against a melanoma antigen

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FEBS Press

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Early TRAIL-engagement elicits potent multimodal targeting of melanoma by CD34+ progenitor cell-derived NK cells

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ROTACs leverage signaling-incompetent R-spondin for targeted protein degradation

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Decreased melanoma CSF-1 secretion by Cannabigerol treatment reprograms regulatory myeloid cells and reduces tumor progression

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  DOI: 10.1080/2162402X.2023.2219164
  
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ICOS DNA methylation regulates melanoma cell-intrinsic ICOS expression, is associated with melanoma differentiation, prognosis, and predicts response to immune checkpoint blockade

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