325 Matching Annotations
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    High-throughput combination screening of Pidnarulex and other G-quadruplex ligands in multi-cell type tumor spheroids
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    sciencedirect.com/science/article/pii/S2472555225000772
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    Development of retinoid nuclear receptor pathway antagonists through targeting aldehyde dehydrogenase 1A3
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    Cannabidivarin directly targets the immunosuppressive activity of regulatory myeloid cells in tumors
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    Systematic design of DMBT1-derived peptides correlating physicochemical properties and sequence motifs with siRNA delivery and efficacy in cancer therapy
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    Optimized arenaviruses with tumor-tropic mutations promote safe anti-tumor efficacy via sustainable immune modulatory properties
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    A cancer-specific antigen drives histone acetylation by stabilizing the acetyltransferases
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    Inhibiting Cyclin-Dependent Kinase 13-Mediated Nuclear Ubiquitous Casein Kinase and Cyclin-Dependent Kinase Substrate 1 Phosphorylation Facilitates Oxidative Stress-Induced Apoptosis in Melanoma
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    CDH3-AS1 antisense RNA enhances P-cadherin translation and acts as a tumor suppressor in melanoma
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    USP9X is a mechanosensitive deubiquitinase that controls tumor cell invasiveness and drug response through YAP stabilization
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  14. Sep 2025
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    Phase Ib Study of Pembrolizumab in Combination with Intratumoral Injection of Clostridium novyi-NT in Patients with Advanced Solid Tumors
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    RAD23B acquires a copper metalloadaptor function in amphibian-to-reptile evolution to increase metabolism and regulate genomic integrity
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    NF1 Loss Promotes EGFR Activation and Confers Sensitivity to EGFR Inhibition in NF1 Mutant Melanoma
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    Cytotoxicity of activator expression in CRISPR-based transcriptional activation systems
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  23. Aug 2025
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  33. Jul 2025
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  42. Jun 2025
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  58. May 2025
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  68. Apr 2025
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  78. Mar 2025
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    Lactylation of LSD1 is an acquired epigenetic vulnerability of BRAFi/MEKi-resistant melanoma
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    Simultaneous CRISPR screening and spatial transcriptomics reveal intracellular, intercellular, and functional transcriptional circuits
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    Overexpression of LMOD1 induces oxidative stress and enhances cell apoptosis of melanoma through the RIG-I like receptor pathway
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    Recognition of MR1-antigen complexes by TCR Vγ9Vδ2
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    Realigned transsulfuration drives BRAF-V600E-targeted therapy resistance in melanoma
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    Lymph node macrophages drive immune tolerance and resistance to cancer therapy by induction of the immune-regulatory cytokine IL-33
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    The NF1 tumor suppressor regulates PD-L1 and immune evasion in melanoma
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  90. Feb 2025
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    An epitope-directed mRNA vaccine inhibits tumor metastasis through the blockade of MICA/B α1/2 shedding
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    MR1 gene and protein expression are enhanced by inhibition of the extracellular signal-regulated kinase ERK
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    The E3 ubiquitin ligase FBXO38 maintains the antitumor function of natural killer cells by sustaining IL-15R signaling
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    Targeting Tumor-Associated Sialic Acids using Chimeric Switch Receptors based on Siglec-9 Enhances the Antitumor Efficacy of Engineered T Cells
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    The IAP antagonist tolinapant enhances the anti-tumor activity of cell therapies
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  146. Mar 2024
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  199. Mar 2023
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  203. Feb 2023
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  205. Jan 2023
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  209. Dec 2022
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  212. Nov 2022
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    Potent and selective PTDSS1 inhibitors induce collateral lethality in cancers with PTDSS2 deletion
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  220. Oct 2022
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  226. Sep 2022
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