415 Matching Annotations
  1. Oct 2026
  2. www.science.org www.science.org
    Computational design of optimized and preferentially paired human TCR constant regions for improved T cell function
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    science.org/doi/10.1126/sciadv.aeb9189
  3. Sep 2026
  4. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Flavasperfurans A and B, Two New Asperfuran Derivatives From the Marine-Derived Fungus Aspergillus flavus
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    onlinelibrary.wiley.com/doi/10.1002/cbdv.71713
  5. www.sciencedirect.com www.sciencedirect.com
    Mitochondrial ATP promotes T cell differentiation through chromatin accessibility
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    sciencedirect.com/science/article/pii/S0092867426009967
  6. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.70657
  7. www.sciencedirect.com www.sciencedirect.com
    Mechanistic modeling reveals a configurable AP-1 network governing cell-state heterogeneity and adaptive plasticity in melanoma cells
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    sciencedirect.com/science/article/pii/S2211124726010430
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    PPM1L-dependent PD-L1 dephosphorylation orchestrates tumor-type-specific ubiquitin ligase recognition to govern its degradation
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    sciencedirect.com/science/article/pii/S2211124726010338
  9. www.nature.com www.nature.com
    PTBP1 controls oncogenic transcript processing and maintenance of acute myeloid leukemia
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    nature.com/articles/s41375-026-03098-8
  10. Aug 2026
  11. www.sciencedirect.com www.sciencedirect.com
    Scalable generation of hematopoietic stem cell-engineered off-the-shelf mono-specific cytotoxic T cells targeting solid tumors
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    sciencedirect.com/science/article/pii/S2666379126004155
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Hallachrome, a marine anthraquinone, impairs cell proliferation by acting as a functional mitochondrial uncoupler in A375 melanoma cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC13474988/
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Selective mRNA translation determines adaptative mutability of melanoma cells to anti-BRAF/MEK combination therapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC13470486/
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Salmonella Typhimurium hijacks a host glucose transporter for intravacuolar proliferation
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    pmc.ncbi.nlm.nih.gov/articles/PMC13455383/
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    A stress-adaptive lipid kinase axis defines metabolic vulnerabilities in neuroendocrine prostate cancer
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    sciencedirect.com/science/article/pii/S1535610826003120
  16. Jul 2026
  17. www.science.org www.science.org
    Discovery of TYR inhibitors from de novo molecular generation to dual-track lead optimization: “Competition” between AI and chemists
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    science.org/doi/10.1126/sciadv.aeg0376
  18. link.springer.com link.springer.com
    Metabolic buffering restricts phenotype switching in melanoma
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    link.springer.com/article/10.1038/s44318-026-00857-2
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    BRAF Inhibition–Associated Nuclear Remodeling is Linked to Cancer-Associated Fibroblast Activation
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    pmc.ncbi.nlm.nih.gov/articles/PMC13373777/
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Amides Derived From Sclareolide as Cytotoxic Agents
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    pmc.ncbi.nlm.nih.gov/articles/PMC13372051/
  21. www.sciencedirect.com www.sciencedirect.com
    A xanthone derivative MGS-3, confers protection against Staphylococcus aureus infection through SarA-mediated inhibition of alpha-hemolysin expression
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    sciencedirect.com/science/article/pii/S0882401026004249
  22. www.science.org www.science.org
    Virome-wide ubiquitin ligase discovery reveals diverse mechanisms of immune evasion
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    science.org/doi/10.1126/science.aec6299
  23. 54.241.53.176 54.241.53.176
    can-25-0786-html.html
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    54.241.53.176/7d4b56be0c3ba37e26d79ae4dd98c78fdc80cb6d/can-25-0786-html.html
  24. aacrjournals.org aacrjournals.org
    Engineering T Cells with a Tumor-Reactive Chimeric T Cell Receptor Reduces Exhaustion and Promotes Persistence to Elicit Enhanced Antitumor Responses
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    aacrjournals.org/cancerres/article/86/11/2688/785304/Engineering-T-Cells-with-a-Tumor-Reactive-Chimeric
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    A viral ORFeome library for systems-level genetic dissection of host-pathogen interactions
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    sciencedirect.com/science/article/pii/S0092867426005830
  26. 54.241.53.176 54.241.53.176
    Mitochondrial translocation of MDM2 and TFAM reprograms metabolism in treatment-refractory cancers
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    54.241.53.176/b2ad43df4b0cad196082fde33923416f2cb86ae8/s41698-025-01257-1_reference-html.html
  27. Jun 2026
  28. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Driver Mutation Subtypes Differentially Shape Immune Evasion Landscapes in Melanoma: An AI-Driven Inflammatory Pathway Model Implicating CCNE1
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    onlinelibrary.wiley.com/doi/10.1155/humu/6776070
  29. www.biorxiv.org www.biorxiv.org
    ImmTACs overcome cytotoxic T cell suppression
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    biorxiv.org/content/10.64898/2026.03.20.713194v3
  30. chemistry-europe.onlinelibrary.wiley.com chemistry-europe.onlinelibrary.wiley.com
    Design and Synthesis of N-Heteroacridone Derivatives and Their Ferroptosis-Inducing Activity Against Human Melanoma
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    chemistry-europe.onlinelibrary.wiley.com/doi/full/10.1002/cmdc.202501070
  31. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Effects of Arylsulfatase B and Pembrolizumab in combination on progression of metastatic melanoma in the B16F10 syngeneic mouse model
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    pmc.ncbi.nlm.nih.gov/articles/PMC13265294/
  32. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    DGAT1 Inhibition Induces Ferroptosis and Enhances Cancer Immunotherapy Efficacy
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    pmc.ncbi.nlm.nih.gov/articles/PMC13266341/
  33. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Acquired resistance to the PRMT5 inhibitor confers collateral sensitivity to MEK inhibition in MTAP-null non-small cell lung cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13131504/
  34. May 2026
  35. www.sciencedirect.com www.sciencedirect.com
    Protocol for validating drug efficacy and safety in scalable 96-well platforms of human cortical organoids and melanoma brain metastases
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    sciencedirect.com/science/article/pii/S2666166726002212
  36. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Genome-Wide CRISPR Screen Identifies a microRNA Orchestrating Pleiotropic Resistance to Targeted Therapy and T Cell Immunity in Melanoma
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202515158
  37. www.sciencedirect.com www.sciencedirect.com
    Chromatin architectures underlying plasmid-based assays for regulatory variant effects
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    sciencedirect.com/science/article/pii/S1097276526002819
  38. onlinelibrary.wiley.com onlinelibrary.wiley.com
    First GC/MS Profiling and Cytotoxic Evaluation of Physalis acutifolia (Solanaceae) Essential Oils: Insights From Molecular Docking and ADME Predictions
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    onlinelibrary.wiley.com/doi/10.1002/cbdv.71312
  39. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Chemical Constituents of Deep-Sea-Derived Fungus Penicillium citrinum W17 and Their Ferroptosis Inhibitory Activity
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    onlinelibrary.wiley.com/doi/10.1002/cbdv.71299
  40. aacrjournals.org aacrjournals.org
    Lipid Nanoparticle-Encapsulated mRNAs Encoding Tumor-Specific Toxin Proteins Selectively Target Cancer Cells and Stimulate T Cell Infiltration
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    aacrjournals.org/cancerres/article/85/19/3706/765871/Lipid-Nanoparticle-Encapsulated-mRNAs-Encoding
  41. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Acquired resistance to the PRMT5 inhibitor confers collateral sensitivity to MEK inhibition in MTAP-null non-small cell lung cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13131504/
  42. Apr 2026
  43. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A Moderate-Affinity Antibody–Drug Conjugate Targeting B7-H3 Exerts Potent Antitumor Efficacy
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    pmc.ncbi.nlm.nih.gov/articles/PMC13118972/
  44. www.biorxiv.org www.biorxiv.org
    A microbiota-derived bile acid overcomes antibiotic-induced hyporesponsiveness to immune checkpoint therapy by enhancing CD8+ T cell antitumor immunity
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    biorxiv.org/content/10.64898/2026.04.15.718788v1
  45. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PALINCODE: Recording cell lineage with ternary palindromic CRISPR bits
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    pmc.ncbi.nlm.nih.gov/articles/PMC13105057/
  46. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    An antibody-drug conjugate designed through clone and isotype selection restricts the growth of CSPG4-expressing triple-negative breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13096323/
  47. aacrjournals.org aacrjournals.org
    The allogeneic FAP-CAR-IL15 iNKT therapy MiNK-215 remodels the tumor stroma to enhance antitumor immunity
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    aacrjournals.org/cancerimmunolres/article/14/2/243/771961/The-Allogeneic-FAP-CAR-IL15-iNKT-Therapy-MiNK-215
  48. pubs.acs.org pubs.acs.org
    Universal Nanovial Screening Enables Functional Discovery of Metabolite-Reactive T-Cell Receptors for Cancer Therapy
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    pubs.acs.org/doi/10.1021/acsnano.5c22721
  49. 54.241.53.176 54.241.53.176
    kirichenko-et-al-2026-hybrid-channels-containing-the-dup7-subunit-mediate-resistance-to-7-nachr-targeting-therapy-in-html.html
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    54.241.53.176/bc5771ba3f9181c34993ca57bf5b697ca7182de4/kirichenko-et-al-2026-hybrid-channels-containing-the-dup7-subunit-mediate-resistance-to-7-nachr-targeting-therapy-in-html.html
  50. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The p53 tumor suppressor modulates the expression of proteins that control natural killer cell activity
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    pmc.ncbi.nlm.nih.gov/articles/PMC13072665/
  51. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Nutrient Availability Dictates Cancer Metabolism–Based Therapeutic Responses to Nononcology Drugs
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    pmc.ncbi.nlm.nih.gov/articles/PMC13055633/
  52. www.sciencedirect.com www.sciencedirect.com
    Nonsense-mediated mRNA decay inhibition reshapes the cancer immunopeptidome
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    sciencedirect.com/science/article/pii/S1074761326000750
  53. www.sciencedirect.com www.sciencedirect.com
    A general tyrosinase-responsive prodrug strategy: design and synthesis of melanoma-selective anticancer agents
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    sciencedirect.com/science/article/pii/S0968089626001045
  54. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CDK11 inhibition induces cytoplasmic p21 WAF1 splice variant by p53 stabilisation and SF3B1 inactivation
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    pmc.ncbi.nlm.nih.gov/articles/PMC13042413/
  55. www.sciencedirect.com www.sciencedirect.com
    A harmless-to-harmful switchable and spatiotemporally activated nano-CRISPR hierarchically amplifies ferroptosis in melanoma
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    sciencedirect.com/science/article/pii/S2666379126001357
  56. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    THC and CBD Induce Heme Oxygenase-1-Dependent Cell Death and Trigger Mitochondrial Dysfunction in Human Melanoma and Cutaneous Squamous Cell Carcinoma Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC13024539/
  57. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Secretome From Human Micro-Fragmented Adipose Tissue Affects In Vitro Monocytes/Macrophages Inflammatory Activity by ICAM-1 Expression
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    onlinelibrary.wiley.com/doi/10.1155/mi/9475320
  58. Mar 2026
  59. 54.241.53.176 54.241.53.176
    1-s2.0-S2589004226008680-main-html.html
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    54.241.53.176/aa623c97d534dc083ac52ef5d52a1404fcf84e38/1-s2.0-S2589004226008680-main-html.html
  60. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    BGN/MDK Axis in the Melanoma Tumor Microenvironment Strengthens Tumor Malignancy by Modulating Cancer Cells and Cancer-Associated Fibroblasts Crosstalk
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202514590
  61. www.sciencedirect.com www.sciencedirect.com
    Early-stage multi-cancer detection through a plasma extracellular vesicle protein signature
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    sciencedirect.com/science/article/pii/S2666379126001114
  62. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Quantification of Single‐Cell Cysteine Using an Electrochemical Nanosensor for Predicting Tumor Disulfidptosis Susceptibility
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    pmc.ncbi.nlm.nih.gov/articles/PMC12955924/
  63. www.cell.com www.cell.com
    Intracellular cyclization-coupled peptide library screening yields potent transcription factor antagonists
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    cell.com/cell-chemical-biology/fulltext/S2451-9456(26)00034-6
  64. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Sym024 interacts with a unique epitope on the CD73 homodimer, favoring effective bivalent binding to improve anti-PD1 therapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12950896/
  65. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    THC and CBD Induce Heme Oxygenase-1-Dependent Cell Death and Trigger Mitochondrial Dysfunction in Human Melanoma and Cutaneous Squamous Cell Carcinoma Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC13024539/
  66. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    VIVID: A qPCR-Based Platform for Sensitive and Quantitative In Vivo Tracking of Extracellular Vesicles
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    advanced.onlinelibrary.wiley.com/doi/full/10.1002/adfm.202526604
  67. Feb 2026
  68. 54.241.53.176 54.241.53.176
    1-s2.0-S1525001626001218-main-html.html
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    54.241.53.176/e46a61ffc36b464c7c6327b10f9b91e9750953b1/1-s2.0-S1525001626001218-main-html.html
  69. www.sciencedirect.com www.sciencedirect.com
    Functional nutrient-genetic profiling reveals biotin and FBXW7 are essential to bypass glutamine addiction
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    sciencedirect.com/science/article/pii/S1097276526000973
  70. www.sciencedirect.com www.sciencedirect.com
    A multiplex, prime editing framework for identifying drug resistance variants at scale
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    sciencedirect.com/science/article/pii/S2666979X26000297
  71. www.sciencedirect.com www.sciencedirect.com
    A GPX1-OSBPL8 axis mediates noncanonical in vivo ferroptosis and cancer growth suppression
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    sciencedirect.com/science/article/pii/S0092867426000565
  72. www.sciencedirect.com www.sciencedirect.com
    The transcriptional repressor Fli1 inhibits proteostasis during nutrient stress to limit NK cell persistence in solid tumors
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    sciencedirect.com/science/article/pii/S107476132600035X
  73. www.sciencedirect.com www.sciencedirect.com
    Hypoxia restores the acidosis-induced inhibition of cancer cell dissemination
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    sciencedirect.com/science/article/pii/S2211124726000483
  74. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.70357
  75. journals.plos.org journals.plos.org
    The lipid-metabolic enzyme HSD17B12 drives lysosomal degradation of PD-L1 potentiating anti-tumor immunity in a mouse model
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    journals.plos.org/plosbiology/article
  76. Jan 2026
  77. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ATAD2 drives melanoma growth and progression and inhibits ferroptosis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12852765/
  78. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Extracellular vesicles released from melanoma cells constitutively expressing MHC class II promote immune evasion and cancer progression
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.70414
  79. www.sciencedirect.com www.sciencedirect.com
    Systematic annotation of orphan RNAs reveals blood-accessible molecular barcodes of cancer identity and cancer-emergent oncogenic drivers
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    sciencedirect.com/science/article/pii/S2666379125006500
  80. www.sciencedirect.com www.sciencedirect.com
    CRISPR screens in the context of immune selection identify CHD1 and MAP3K7 as mediators of cancer immunotherapy resistance
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    sciencedirect.com/science/article/pii/S266637912500638X
  81. www.biorxiv.org www.biorxiv.org
    NF1 Loss Remodels Tumor Niches for Immune Evasion
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    biorxiv.org/content/10.64898/2026.01.11.698818v1
  82. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Unveiling the Anticancer Potential of Verbascum aydogdui: Isolation, Characterization, and In Vitro Studies
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    onlinelibrary.wiley.com/doi/10.1002/cbdv.202503376
  83. www.sciencedirect.com www.sciencedirect.com
    Ubiquitination-directed cytosolic DNA degradation governs cGAS-STING-mediated immune response to DNA damage
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    sciencedirect.com/science/article/pii/S1535610825005471
  84. pubs.acs.org pubs.acs.org
    Theranostic Nonstoichiometric, Multivalent Bismuth (Bi)-Based Nanospheres for Selective Spontaneous Melanoma Treatment
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    pubs.acs.org/doi/full/10.1021/acsami.5c20966
  85. www.sciencedirect.com www.sciencedirect.com
    5-HT reuptake blockade induces pyroptosis in BRAFV600E-mutated melanomas via remodeling histone serotonylation
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    sciencedirect.com/science/article/pii/S266637912500610X
  86. Dec 2025
  87. www.sciencedirect.com www.sciencedirect.com
    Paeoniflorin Promotes Therapeutic Senescence in Melanoma through Endoplasmic Reticulum Stress and the Calpain1/ERK5/p27 Axis
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    sciencedirect.com/science/article/pii/S0944711325013649
  88. www.nature.com www.nature.com
    Engineered antibodies that stabilize drug-modified KRASG12C neoantigens enable selective and potent cross-HLA immunotherapy
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    nature.com/articles/s41467-025-66132-w
  89. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Comprehensive analysis based on spatial domains identifies CD44 as a potential target of puerarin
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    pmc.ncbi.nlm.nih.gov/articles/PMC12712269/
  90. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Machine learning-based development of a cytotoxicity prediction model for NK cell therapy in cancers
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    pmc.ncbi.nlm.nih.gov/articles/PMC12698772/
  91. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.70169
  92. Nov 2025
  93. www.sciencedirect.com www.sciencedirect.com
    UMP functions as an endogenous regulator of NR4A1 to control gastric cancer progression
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  189. Feb 2025
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  191. aacrjournals.org aacrjournals.org
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  197. Jan 2025
  198. www.cell.com www.cell.com
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  199. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
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  200. Dec 2024
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  206. Nov 2024
  207. pubs.acs.org pubs.acs.org
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  213. Oct 2024
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  215. Sep 2024
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  218. Aug 2024
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