307 Matching Annotations
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    Cytotoxicity of activator expression in CRISPR-based transcriptional activation systems
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    nature.com/articles/s41467-025-63570-4
  3. Aug 2025
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    DFFB suppresses interferon to enable cancer persister cell regrowth
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    Targeting lipid scrambling potentiates ferroptosis and triggers tumor immune rejection
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    Targeting lipid scrambling potentiates ferroptosis and triggers tumor immune rejection
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    Preclinical Evaluation of DB-1419, a Novel Bifunctional and Bispecific Anti–B7-H3 × PD-L1 Antibody–Drug Conjugate
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    A Nanovial-Based Platform for Functional Discovery of Antigen-Reactive TCRs from Unconventional T Cells
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    biorxiv.org/content/10.1101/2025.08.06.668816v2
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    Tissue-dependent mechanosensing by cells derived from human tumors
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    A pan-KRAS inhibitor and its derived degrader elicit multifaceted anti-tumor efficacy in KRAS-driven cancers
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    Pathway metabolite ratios reveal distinctive glutamine metabolism in a subset of proliferating cells
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    Investigating the relationship Between AMBRA1 and Cell Proliferation in Melanoma
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  13. Jul 2025
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    Secretogranin 2 binds LILRB4 resulting in immunosuppression
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    Direct transdifferentiation of tumorigenic melanoma cells induces tumor cell reversion
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    IgSF11–RAP1 signaling promotes cell migration and invasion of cutaneous melanoma
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    PHGDH Induction by MAPK is Essential for Melanoma Formation and Creates an Actionable Metabolic Vulnerability
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    CDC42-effector interaction inhibitors alter patterns of vessel arborization in skin and tumors in vivo
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    Salmonella hijacks a host glucose transporter for intravacuolar proliferation
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    A Rac-specific competitive inhibitor of guanine nucleotide binding reduces metastasis in triple-negative breast cancer
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    Identification of UBE3C as an E3 ubiquitin ligase for mutant BRAF
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  22. Jun 2025
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    Ribosomal RNA transcription regulates splicing through ribosomal protein RPL22
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    Targeting Oncofoetal Chondroitin Sulphate Allows Identification of Tumour‐Derived Extracellular Vesicles
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    A phase 1/2 clinical trial of invariant natural killer T cell therapy in moderate-severe acute respiratory distress syndrome
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    Single-Cell Transcriptomic Landscape Deciphers Intratumoral Heterogeneity and Subtypes of Acral and Mucosal Melanomas
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    EZH2 loss during metabolic stress drives restoration of MHC class I machinery in melanoma
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  38. May 2025
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    Tumorigenesis Driven by BRAFV600E Requires Secondary Mutations That Overcome Its Feedback Inhibition of RAC1 and Migration
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    Liposome-Polymer Nanoparticles Loaded with Copper Diethyldithiocarbamate and 6-Bromo-Indirubin-3′-Oxime Enable the Treatment of Refractive Melanoma
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  48. Apr 2025
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    LncRNA SLNCR phenocopies the E2F1 DNA binding site to promote melanoma progression
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    VAX014 Activates Tumor-Intrinsic STING and RIG-I to Promote the Development of Antitumor Immunity
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    Homeostatic regulation of nucleoporins is a central driver of nuclear pore biogenesis
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  58. Mar 2025
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    Lactylation of LSD1 is an acquired epigenetic vulnerability of BRAFi/MEKi-resistant melanoma
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    Simultaneous CRISPR screening and spatial transcriptomics reveal intracellular, intercellular, and functional transcriptional circuits
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    Overexpression of LMOD1 induces oxidative stress and enhances cell apoptosis of melanoma through the RIG-I like receptor pathway
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    Recognition of MR1-antigen complexes by TCR Vγ9Vδ2
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    Realigned transsulfuration drives BRAF-V600E-targeted therapy resistance in melanoma
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    Lymph node macrophages drive immune tolerance and resistance to cancer therapy by induction of the immune-regulatory cytokine IL-33
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    The NF1 tumor suppressor regulates PD-L1 and immune evasion in melanoma
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  70. Feb 2025
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    An epitope-directed mRNA vaccine inhibits tumor metastasis through the blockade of MICA/B α1/2 shedding
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    MR1 gene and protein expression are enhanced by inhibition of the extracellular signal-regulated kinase ERK
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    The E3 ubiquitin ligase FBXO38 maintains the antitumor function of natural killer cells by sustaining IL-15R signaling
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    Targeting Tumor-Associated Sialic Acids using Chimeric Switch Receptors based on Siglec-9 Enhances the Antitumor Efficacy of Engineered T Cells
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    ILT2 and ILT4 drive myeloid suppression via both overlapping and distinct mechanisms
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    The IAP antagonist tolinapant enhances the anti-tumor activity of cell therapies
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  78. Jan 2025
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    CDK2 activity crosstalk on the ERK kinase translocation reporter can be resolved computationally
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    RECQL4 affects MHC class II‐mediated signalling and favours an immune‐evasive signature that limits response to immune checkpoint inhibitor therapy in patients with malignant melanoma
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  81. Dec 2024
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    The carbonyl nucleobase adduct M3Ade is a potent antigen for adaptive polyclonal MR1-restricted T cells
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    Transcriptional and functional regulation of cell cycle and UV response by PPARβ in human skin epidermal cells
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    Nucleo-cytosolic acetyl-CoA drives tumor immune evasion by regulating PD-L1 in melanoma
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    ACSS1-dependent acetate utilization rewires mitochondrial metabolism to support AML and melanoma tumor growth and metastasis
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  87. Nov 2024
  88. pubs.acs.org pubs.acs.org
    Silica Nanoparticles Decorated with Ceria Quantum Dots Modulate Intra- and Extracellular Reactive Oxygen Species Formation and Selectively Reduce Human A375 Melanoma Cell Proliferation
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    A peptide encoded by LINC00944 suppresses the growth of melanoma cells by diminishing EP400-MYC interaction
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    C19MC Drives Nucleolar Invasion of Mitochondria and Meiotic Nuclear Division in Human Cancers
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    PRDX6 dictates ferroptosis sensitivity by directing cellular selenium utilization
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    Itaconate transporter SLC13A3 impairs tumor immunity via endowing ferroptosis resistance
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    Dysregulation of R-loop homeostasis shapes the immunosuppressive microenvironment and induces malignant progression in melanoma
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  94. Oct 2024
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    RAF-Mutant Melanomas Differentially Depend on ERK2 Over ERK1 to Support Aberrant MAPK Pathway Activation and Cell Proliferation
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  96. Sep 2024
  97. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Precision Oncology and Systemic Targeted Therapy in Pseudomyxoma Peritonei
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    Aged fibroblast-derived extracellular vesicles promote angiogenesis in melanoma
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  99. Aug 2024
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