1,143 Matching Annotations
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    Direct binding of the C-terminal sequences of Bim and Bak contributes to efficient Bak activation
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    nature.com/articles/s41418-026-01848-w
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    Mitochondrial Fis1 tunes Rab7A activity via TBC1D15 modulating STING degradation
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    sciencedirect.com/science/article/pii/S2211124726010727
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    Mutant KRAS-m6A Epitranscriptome Axis Promotes Colorectal Cancer and is a Therapeutic Target
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.77627
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    Genome-wide chromatin recording resolves dynamic cell state changes
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    pmc.ncbi.nlm.nih.gov/articles/PMC13540299/
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    ALDH2 regulates oxaliplatin sensitivity via PDE4B in p53-mutant colorectal cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13539918/
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    Metabolic-cell-death gene trio predicts survival and cuproptosis sensitivity in colorectal cancer
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  8. Sep 2026
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    Centrosome-centromere capture range, rather than centrosome arrangement, determines multipolar chromosome segregation pattern after whole-genome duplication
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    biorxiv.org/content/10.64898/2026.08.24.746909v1
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    Systematic Targeting of Protein Complexes with Molecular COUPLrs
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    CONCR lncRNA organizes a 3′-end structural domain that engages DDX11 for DNA replication and sister chromatid cohesion
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    sciencedirect.com/science/article/pii/S1097276526005514
  12. Aug 2026
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    Lactobacillus salivarius potentiates gastrointestinal cancer immunotherapy through its metabolite chenodeoxycholic acid
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    The CNNM-binding interface drives PRL-3-dependent tumor progression in de novo cancer models
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    pH-Responsive Ultrasmall Iron Oxide Nanoassemblies for Activatable T2/T1 Magnetic Resonance Imaging
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    advanced.onlinelibrary.wiley.com/doi/10.1002/anbr.70152
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    Metabolic Immunosuppression Mediated by Proliferative CD168+ TAMs in Colon Cancer
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    Fibroblasts selectively modulate immune cell-derived cytokine effects on tumor cells in colorectal cancer
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    Synthesis and <i>In Vitro</i> Anticancer Activity of New Acridone Derivatives: Computational DFT and Molecular Docking Studies
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    onlinelibrary.wiley.com/doi/10.1002/cbdv.71593
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    A Novel tRNA Half mt-5’-tiRNA-Tyr Promotes Colorectal Cancer Proliferation via Inducing HARS2 Succinylation
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    Cpumycins A–C, Aminated Benzoic Dimers from Streptomyces sp. CPU-W6, and Their Potential Cardioprotective Activities
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    Schisandrin A ameliorates obesity and MAFLD through bile acid context-dependent modulation of intestinal FXR signaling
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    Targeting colorectal cancer with pyrazolo[4,3-e][1,2,4]triazine and pyrazolo[4,3-e]tetrazolo[1,5-b][1,2,4]triazine sulfonamides: comprehensive in vitro evaluation
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    CLK3 regulates tumor angiogenesis by modulating HIF1α ubiquitination
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    Targeted phenylboronic acid-rosuvastatin based nanoconstructs: A novel therapeutic avenue for treatment of colorectal cancer
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    GPR39 Suppresses Ferroptosis via the Nrf2/SLC7A11 Axis and Reduces the Sensitivity of Colorectal Cancer to Anti-PD-1 Immunotherapy
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    Phytochemical Profiling and Biological Evaluation of Anthyllis henoniana Organs: Integrated In Vitro and Molecular Docking Insights Into Antioxidant, Anti‐Inflammatory, and Cytotoxic Potential
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    The dystonia-associated Torsin1A sustains CLCC1 function in membrane fusion of the nuclear envelope for NPC biogenesis
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    Discovery and Optimization of a WRN Helicase Inhibitor Series through Structure-Guided Drug Design from a Covalent Fragment Binding Insight
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  39. Jul 2026
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    Extracellular vesicles derived from fetal stem cells in early pregnancy modulate glycolysis and lipid metabolism to induce apoptosis in cancer cells
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    DHODH is a synthetic lethal target in PIK3CA-mutant colorectal cancer
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    Dynamic regulation of origin firing factors links CDK activity to dormant origin activation
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    UFMylation Suppresses Hepatocellular Carcinoma Metastasis by Inhibiting β-catenin-Driven Hybrid EMT and NK Cell Evasion
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    Stress-Induced ADGRL4 Orchestrates Tumor Progression and Metastasis by Inhibiting YAP1 Signaling and Activating Angiogenesis
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    Epigenetic silencing of the liver-specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation
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    SOCS5 suppresses antitumor immunity in colorectal cancer by promoting IFNAR1 ubiquitylation and type I interferon response
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    Combining PD-L1 blockade with a second-generation HSP110 inhibitor enhances antitumor immunity in colorectal cancer
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    A CDK1 phospho-switch reprograms TRAIP to unload replisomes in mitosis
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  60. Jun 2026
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    Targeting SUV4-20H Epigenetic Enzymes Enhances Topoisomerase II Poisoning in Prostate Cancer
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    Distinct ERK and PI3K dependencies mediate a heterogeneous response to RAS(ON) inhibition in KRAS-mutant colorectal cancer
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    Machine learning algorithms develop a tumor-educated platelets-related gene signature to predict colorectal cancer prognosis and therapy response
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    VANGL1 links angiogenesis–stemness programs and tumor microenvironment remodeling: a pan-cancer, multi-omics study with translational validation
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    PI3K and MAPK Signaling Nodes Serve as Divergent Drivers of Phenotypic Plasticity in Cancer-Associated Fibroblasts in Colorectal Cancer
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    hSpindly dynamics modulate spindle assembly checkpoint signaling, promoting resistance to mitotic inhibitors
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    Rambutan (Nephelium lappaceum L.) Shell as a Source of Polyphenols: Chemical Characterization and Biological Activities
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    High-throughput screening identifies NT-1 that synergizes with MRTX1133 against acquired resistant KRASG12D colorectal cancer
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  72. www.mdpi.com www.mdpi.com
    Docetaxel Oral Delivery System Using Natural Nanoparticles Derived from Ganoderma: Enhanced Pharmacokinetics, Potent Cytotoxicity, and Macrophage-Activating Properties
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    Mesoporous silica nanoparticles as nanocarriers for 2′-hydroxy-2-fluorochalcone: synthesis, characterization, and anticancer activity against colorectal cancer cells
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    DDR1 Promotes Immune Evasion in Colorectal Cancer by Orchestrating IL33-Mediated M2-like Polarization of Tumor-Associated Macrophages
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    Triple-armed oncolytic HSV enhances antitumor immunity by remodeling the tumor microenvironment in subcutaneous murine CRC
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    Exploring Synergistic Potential of Sorafenib and Atorvastatin to Launch Apoptosis and Ferroptosis-driven Mixed Cell Death Mechanism in Colorectal Cancer
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    link.springer.com/article/10.1208/s12249-026-03461-z
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    RNF207 promotes colorectal cancer growth by regulating the Hippo–YAP pathway via enhanced MST1 ubiquitination and degradation
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    Intravenous paclitaxel delivered by a vitamin E nanocarrier as a safe and economical alternative to albumin-bound nanoparticles
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  79. May 2026
  80. www.sciencedirect.com www.sciencedirect.com
    Targeting EP2/EP4-driven expansion of suppressive VSIG4high macrophages overcomes immunotherapy resistance in colorectal cancer
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    Ethanol promotes oxaliplatin resistance in colorectal cancer by activating the TGF‑β/Smad/P21 signaling axis
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    pmc.ncbi.nlm.nih.gov/articles/PMC13213347/
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    Licoisoflavone A potentiates oxaliplatin efficacy in colorectal cancer by dual targeting arginine metabolism of tumor microenvironment and cancer cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC13217967/
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    CDK6/4 inactivates BAP1 deubiquitinase destabilizing VHL to promote metastatic colonization in liver
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    Druggable β-catenin palmitoyl-switch coordinates immune evasion via immunogenic ferroptosis resistance and PD-L1-mediated immunosuppression
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    sciencedirect.com/science/article/pii/S2666379126002545
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    An HOCl-activated chemiluminescent prodrug enabling self-reporting camptothecin release and imaging-guided therapy in peritoneal metastasis
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    sciencedirect.com/science/article/pii/S0968089626001732
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    CAMK1 Suppresses Anoikis Resistance and Liver Metastasis in Colorectal Cancer
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