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  1. Oct 2024
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Combined Oxygen-Enhanced MRI and Perfusion Imaging Detect Hypoxia Modification from Banoxantrone and Atovaquone and Track Their Differential Mechanisms of Action
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    1. scibot 04 Oct 2024
      RRID:CVCL_0291

      DOI: 10.1158/2767-9764.CRC-24-0315

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    ncbi.nlm.nih.gov/pmc/articles/PMC11443776/
  3. www.biorxiv.org www.biorxiv.org
    Metabolic mapping of the human solute carrier superfamily
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    1. scibot 03 Oct 2024
      RRID:CVCL_0291

      DOI: 10.1101/2024.09.23.614124

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    biorxiv.org/content/10.1101/2024.09.23.614124v1
  4. aacrjournals.org aacrjournals.org
    Overproduction of Gastrointestinal 5-HT Promotes Colitis-Associated Colorectal Cancer Progression via Enhancing NLRP3 Inflammasome Activation
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    1. scibot 02 Oct 2024
      RRID: CVCL_0291

      DOI: 10.1158/2326-6066.CIR-20-1043

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    aacrjournals.org/cancerimmunolres/article/9/9/1008/666146/Overproduction-of-Gastrointestinal-5-HT-Promotes
  5. aacrjournals.org aacrjournals.org
    2-Hydroxylation of Fatty Acids Represses Colorectal Tumorigenesis and Metastasis via the YAP Transcriptional Axis
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    1. scibot 02 Oct 2024
      RRID: CVCL_0291

      DOI: 10.1158/0008-5472.CAN-20-1517

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    aacrjournals.org/cancerres/article/81/2/289/649623/2-Hydroxylation-of-Fatty-Acids-Represses
  6. www.sciencedirect.com www.sciencedirect.com
    Mitotic ER-mitochondria contact enhances mitochondrial Ca2+ influx to promote cell division
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    1. scibot 02 Oct 2024
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    sciencedirect.com/science/article/pii/S2211124724011458
  7. Sep 2024
  8. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    CASCADES, a novel SOX2 super-enhancer-associated long noncoding RNA, regulates cancer stem cell specification and differentiation in glioblastoma
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    1. scibot 27 Sep 2024
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      DOI: 10.1002/1878-0261.13735

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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13735
  9. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    1. scibot 27 Sep 2024
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13708
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Ctnnb1 enhancer transcriptionally regulates Wnt signaling dosage to balance homeostasis and tumorigenesis of intestinal epithelia
    1
    1. scibot 27 Sep 2024
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      DOI: 10.7554/eLife.98238

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    ncbi.nlm.nih.gov/pmc/articles/PMC11424096/
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TRAP1 modulates mitochondrial biogenesis via PGC-1α/TFAM signalling pathway in colorectal cancer cells
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    1. scibot 26 Sep 2024
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      DOI: 10.1007/s00109-024-02479-9

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    ncbi.nlm.nih.gov/pmc/articles/PMC11416412/
  12. www.sciencedirect.com www.sciencedirect.com
    Fusobacterium nucleatum facilitates anti-PD-1 therapy in microsatellite stable colorectal cancer
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    1. scibot 25 Sep 2024
      CCL-247

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    sciencedirect.com/science/article/pii/S1535610824003180
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Novel immunotherapeutics against LGR5 to target multiple cancer types
    1
    1. scibot 25 Sep 2024
      RRID:CVCL_0291

      DOI: 10.1038/s44321-024-00121-2

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    ncbi.nlm.nih.gov/pmc/articles/PMC11393416/
  14. www.sciencedirect.com www.sciencedirect.com
    Tumour-associated mesenchymal stromal cells modulate macrophage phagocytosis in stromal-rich colorectal cancer via PD-1 signalling.
    1
    1. scibot 25 Sep 2024
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    sciencedirect.com/science/article/pii/S2589004224019266
  15. www.biorxiv.org www.biorxiv.org
    Enhancing efficacy of the MEK inhibitor trametinib with paclitaxel in KRAS-mutated colorectal cancer
    1
    1. scibot 15 Sep 2024
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      DOI: 10.1101/2024.09.05.611458

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    biorxiv.org/content/10.1101/2024.09.05.611458v1
  16. onlinelibrary.wiley.com onlinelibrary.wiley.com
    14-3-3σ restricts YY1 to the cytoplasm, promoting therapy resistance, and tumor progression in colorectal cancer
    1
    1. scibot 15 Sep 2024
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      DOI: 10.1002/ijc.35176

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    onlinelibrary.wiley.com/doi/10.1002/ijc.35176
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RUVBL1/2 Blockade Targets YTHDF1 Activity to Suppress m6A-Dependent Oncogenic Translation and Colorectal Tumorigenesis
    2
    1. scibot 12 Sep 2024
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      DOI: 10.1158/0008-5472.CAN-23-2081

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    ncbi.nlm.nih.gov/pmc/articles/PMC11372367/
  18. www.cell.com www.cell.com
    TEX264 drives selective autophagy of DNA lesions to promote DNA repair and cell survival
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    1. scibot 12 Sep 2024
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      DOI: 10.1016/j.cell.2024.08.020

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    cell.com/cell/fulltext/S0092-8674(24)00911-5
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comprehensive Proteogenomic Profiling Reveals the Molecular Characteristics of Colorectal Cancer at Distinct Stages of Progression
    1
    1. scibot 12 Sep 2024
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      DOI: 10.1158/0008-5472.CAN-23-1878

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    ncbi.nlm.nih.gov/pmc/articles/PMC11372369/
  20. www.sciencedirect.com www.sciencedirect.com
    IDO1 inhibitors are synergistic with CXCL10 agonists in inhibiting colon cancer growth
    1
    1. scibot 11 Sep 2024
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      DOI: 10.1016/j.biopha.2024.117412

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    sciencedirect.com/science/article/pii/S0753332224012976
  21. www.sciencedirect.com www.sciencedirect.com
    Synergistic Anti-tumorigenic Effect of Diosmetin in Combination with 5-Fluorouracil on Human Colon Cancer Xenografts in Nude Mice
    1
    1. scibot 10 Sep 2024
      RRID:CVCL_0291

      DOI: 10.1016/j.bbrc.2024.150677

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    sciencedirect.com/science/article/pii/S0006291X24012130
  22. www.sciencedirect.com www.sciencedirect.com
    Five miRNAs identified in fucosylated extracellular vesicles as non-invasive diagnostic signatures for hepatocellular carcinoma
    1
    1. scibot 06 Sep 2024
      Cat# CCL-247

      DOI: 10.1016/j.xcrm.2024.101716

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    sciencedirect.com/science/article/pii/S2666379124004373
  23. www.sciencedirect.com www.sciencedirect.com
    Dual function of PHF16 in reinstating homeostasis of murine intestinal epithelium after crypt regeneration
    1
    1. scibot 04 Sep 2024
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      DOI: 10.1016/j.devcel.2024.08.009

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    sciencedirect.com/science/article/pii/S1534580724004921
  24. Aug 2024
  25. www.sciencedirect.com www.sciencedirect.com
    RNA interacts with topoisomerase I to adjust DNA topology
    1
    1. scibot 23 Aug 2024
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      DOI: 10.1016/j.molcel.2024.07.032

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    sciencedirect.com/science/article/pii/S1097276524006300
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Jianpi Jiedu Recipe Inhibits Proliferation through Reactive Oxygen Species-Induced Incomplete Autophagy and Reduces PD-L1 Expression in Colon Cancer
    1
    1. scibot 23 Aug 2024
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      DOI: 10.1177/15347354241268064

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    ncbi.nlm.nih.gov/pmc/articles/PMC11331576/
  27. www.biorxiv.org www.biorxiv.org
    Discovery of Z1362873773: A Novel Fascin Inhibitor from a Large Chemical Library for Colorectal Cancer
    1
    1. scibot 22 Aug 2024
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      DOI: 10.1101/2024.08.13.606007

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    biorxiv.org/content/10.1101/2024.08.13.606007v1
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FEBS Press
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    1. scibot 22 Aug 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC10323897/
  29. www.sciencedirect.com www.sciencedirect.com
    CCL19-producing fibroblasts promote tertiary lymphoid structure formation enhancing anti-tumor IgG response in colorectal cancer liver metastasis
    1
    1. scibot 21 Aug 2024
      CVCL_0291

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    sciencedirect.com/science/article/pii/S153561082400271X
  30. www.sciencedirect.com www.sciencedirect.com
    Integrative plasma and fecal metabolomics identify functional metabolites in adenoma-colorectal cancer progression and as early diagnostic biomarkers
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    1. scibot 21 Aug 2024
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    sciencedirect.com/science/article/pii/S1535610824002708
  31. link.springer.com link.springer.com
    Iron Overloading Potentiates the Antitumor Activity of 5-Fluorouracil by Promoting Apoptosis and Ferroptosis in Colorectal Cancer Cells
    1
    1. scibot 20 Aug 2024
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      DOI: 10.1007/s12013-024-01463-x

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    link.springer.com/article/10.1007/s12013-024-01463-x
  32. f1000research.com f1000research.com
    F1000Research Article: Unraveling the Interplay of Autophagy Genes and KLF3/KLF8 in Colorectal Cancer Metastasis: A Bioinformatics and cellular Exploration.
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      DOI: 10.12688/f1000research.150115.1

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    f1000research.com/articles/13-850
  33. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    1. scibot 19 Aug 2024
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      DOI: 10.1111/bph.16497

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16497
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HTS384 NCI60: The Next Phase of the NCI60 Screen
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      DOI: 10.1158/0008-5472.CAN-23-3031

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    ncbi.nlm.nih.gov/pmc/articles/PMC11292194/
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MMP‐9‐dependent proteolysis of the histone H3 N‐terminal tail: a critical epigenetic step in driving oncogenic transcription and colon tumorigenesis
    1
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      DOI: 10.1002/1878-0261.13652

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    ncbi.nlm.nih.gov/pmc/articles/PMC11306514/
  36. onlinelibrary.wiley.com onlinelibrary.wiley.com
    EEF1D stabilized by SRSF9 promotes colorectal cancer via enhancing the proliferation and metastasis
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      DOI: 10.1002/ijc.35039

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    onlinelibrary.wiley.com/doi/10.1002/ijc.35039
  37. www.sciencedirect.com www.sciencedirect.com
    BCAA-producing Clostridium symbiosum promotes colorectal tumorigenesis through the modulation of host cholesterol metabolism
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      DOI: 10.1016/j.chom.2024.07.012

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    sciencedirect.com/science/article/pii/S1931312824002713
  38. www.cell.com www.cell.com
    Peptostreptococcus stomatis promotes colonic tumorigenesis and receptor tyrosine kinase inhibitor resistance by activating ERBB2-MAPK
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    cell.com/cell-host-microbe/abstract/S1931-3128(24)00254-3
  39. 52.53.155.43 52.53.155.43
    The Natural Alkaloid (-)- N-Hydroxyapiosporamide Suppresses Colorectal Tumor Progression as an NF-κB Pathway Inhibitor by Targeting the TAK1-TRAF6 Complex
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    52.53.155.43/8d57977b9b9f6e94560266e27b39ad1669186ba3/acs.jnatprod.3c00125 (1)-html.html
  40. 52.53.155.43 52.53.155.43
    FEBS Press
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    52.53.155.43/55175f335d9d63eca4c96b1d663be208d4b843b1/Molecular Oncology - 2023 - Koob - MND1 enables homologous recombination in somatic cells primarily outside the context of-html.html
  41. bmccancer.biomedcentral.com bmccancer.biomedcentral.com
    Intense endoplasmic reticulum stress (ERS) / IRE1α enhanced Oxaliplatin efficacy by decreased ABCC10 in colorectal cancer cells
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      DOI: 10.1186/s12885-022-10415-8

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    bmccancer.biomedcentral.com/articles/10.1186/s12885-022-10415-8
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Small-molecule NSC59984 induces mutant p53 degradation through a ROS-ERK2-MDM2 axis in cancer cells
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      DOI: 10.1158/1541-7786.MCR-21-0149

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    ncbi.nlm.nih.gov/pmc/articles/PMC8983457/
  43. jeccr.biomedcentral.com jeccr.biomedcentral.com
    Vulnerability to low-dose combination of irinotecan and niraparib in ATM-mutated colorectal cancer
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      DOI: 10.1186/s13046-020-01811-8

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  44. www.sciencedirect.com www.sciencedirect.com
    Therapy-induced DNA methylation inactivates MCT1 and renders tumor cells vulnerable to MCT4 inhibition
    1
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      CCL-247

      DOI: 10.1016/j.celrep.2021.109202

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  45. www.mdpi.com www.mdpi.com
    Targeting AKT/mTOR and Bcl-2 for Autophagic and Apoptosis Cell Death in Lung Cancer: Novel Activity of a Polyphenol Compound
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      CCL-247

      DOI: 10.3390/antiox10040534

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  46. www.embopress.org www.embopress.org
    Unexpected PD‐L1 immune evasion mechanism in TNBC, ovarian, and other solid tumors by DR5 agonist antibodies
    1
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      HCT116

      DOI: 10.15252/emmm.202012716

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  47. www.cell.com www.cell.com
    In Vivo Evidence for Serine Biosynthesis-Defined Sensitivity of Lung Metastasis, but Not of Primary Breast Tumors, to mTORC1 Inhibition
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      CCL-247

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    cell.com/molecular-cell/fulltext/S1097-2765(20)30827-3
  48. www.cell.com www.cell.com
    Membrane Damage during Ferroptosis Is Caused by Oxidation of Phospholipids Catalyzed by the Oxidoreductases POR and CYB5R1
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      CCL-247

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  49. www.mdpi.com www.mdpi.com
    Diketopiperazine-Based, Flexible Tadalafil Analogues: Synthesis, Crystal Structures and Biological Activity Profile
    1
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      ATCC® CCL-247

      DOI: 10.3390/molecules26040794

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  50. Jul 2024
  51. www.sciencedirect.com www.sciencedirect.com
    Translocational attenuation mediated by the PERK-SRP14 axis is a protective mechanism of unfolded protein response
    1
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      Cat#CCL-247

      DOI: 10.1016/j.celrep.2024.114402

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    sciencedirect.com/science/article/pii/S2211124724007307
  52. www.mdpi.com www.mdpi.com
    Upregulation of TET2 and Resistance to DNA Methyltransferase (DNMT) Inhibitors in DNMT1-Deleted Cancer Cells
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      RRID:CVCL_0291

      DOI: 10.3390/diseases12070163

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  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Characterising replisome disassembly in human cells
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      RRID:CVCL_0291

      DOI: 10.1016/j.isci.2024.110260

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    ncbi.nlm.nih.gov/pmc/articles/PMC11269944/
  54. www.sciencedirect.com www.sciencedirect.com
    FANCM promotes PARP inhibitor resistance by minimizing ssDNA gap formation and counteracting resection inhibition
    1
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      Cat# CCL-247

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  55. www.sciencedirect.com www.sciencedirect.com
    Base-resolution m5C profiling across the mammalian transcriptome by bisulfite-free enzyme-assisted chemical labeling approach
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      CCL-247

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  56. www.sciencedirect.com www.sciencedirect.com
    Proteomic analysis reveals a PLK1-dependent G2/M degradation program and a role for AKAP2 in coordinating the mitotic cytoskeleton
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  57. www.sciencedirect.com www.sciencedirect.com
    RNA 5-methylcytosine marks mitochondrial double-stranded RNAs for degradation and cytosolic release
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      RRID:CVCL_0291

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  58. www.sciencedirect.com www.sciencedirect.com
    Identification and characterization of TM4SF1+ tumor self-seeded cells
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  59. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.16489
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DHODH inhibition enhances the efficacy of immune checkpoint blockade by increasing cancer cell antigen presentation
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      CCL-247

      DOI: 10.7554/eLife.87292

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  61. www.cell.com www.cell.com
    A mammalian model reveals inorganic polyphosphate channeling into the nucleolus and induction of a hyper-condensate state
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      CVCL_0291

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    cell.com/cell-reports-methods/fulltext/S2667-2375(24)00179-6
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tumor invasiveness is regulated by the concerted function of APC, formins and Arp2/3 complex
    1
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  63. Jun 2024
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Illuminating Dark Chemical Matter Using the Cell Painting Assay
    1
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      DOI: 10.1021/acs.jmedchem.4c00160

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  65. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Comparing in vitro cytotoxic drug sensitivity in colon and pancreatic cancer using 2D and 3D cell models: Contrasting viability and growth inhibition in clinically relevant dose and repeated drug cycles
    1
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      CVCL_0291

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  66. 52.53.155.43 52.53.155.43
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      RRID:CVCL_0291

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  67. www.biorxiv.org www.biorxiv.org
    POLQ mediates replication-stress induced structural variant formation throughout common fragile sites during mitosis
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  68. www.science.org www.science.org
    DNMT3B splicing dysregulation mediated by SMCHD1 loss contributes to DUX4 overexpression and FSHD pathogenesis
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      DOI: 10.1126/sciadv.adn7732

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  69. www.sciencedirect.com www.sciencedirect.com
    De novo and salvage purine synthesis pathways across tissues and tumors
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  70. www.sciencedirect.com www.sciencedirect.com
    Homeostatic coordination of cellular phosphate uptake and efflux requires an organelle-based receptor for the inositol pyrophosphate IP8
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      CCL-247

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  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bacillamide D produced by Bacillus cereus from the mouse intestinal bacterial collection (miBC) is a potent cytotoxin in vitro
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  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DNMT3B splicing dysregulation mediated by SMCHD1 loss contributes to DUX4 overexpression and FSHD pathogenesis
    1
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  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Integrated analysis of colorectal cancer metastasis identifies characteristics of tumor cell during metastasis
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      DOI: 10.1093/gastro/goae055

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  74. May 2024
  75. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chloroquine-induced DNA damage synergizes with DNA repair inhibitors causing cancer cell death
    1
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      DOI: 10.3389/fonc.2024.1390518

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  77. pubs.acs.org pubs.acs.org
    Anticancer Study on IrIII and RhIII Half-Sandwich Complexes with the Bipyridylsulfonamide Ligand
    2
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      HCT-116

      DOI: 10.1021/acs.inorgchem.3c03801

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      CVCL_427

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  78. link.springer.com link.springer.com
    Regulation of human microglial gene expression and function via RNAase-H active antisense oligonucleotides in vivo in Alzheimer’s disease
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      CVCL_0291

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  79. www.tandfonline.com www.tandfonline.com
    Palindromic carbazole derivatives: unveiling their antiproliferative effect via topoisomerase II catalytic inhibition and apoptosis induction
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      CVCL_427

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  80. 52.53.155.43 52.53.155.43
    Everolimus exerts anticancer effects through inhibiting the interaction of matrix metalloproteinase-7 with syndecan-2 in colon cancer cells
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      DOI: 10.1152/ajpcell.00669.2023

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    52.53.155.43/76598b44d554c4165a9f84a25bc34c671709ff41/lee-et-al-2024-everolimus-exerts-anticancer-effects-through-inhibiting-the-interaction-of-matrix-metalloproteinase-7-html.html
  81. www.sciencedirect.com www.sciencedirect.com
    mTORC1-CTLH E3 ligase regulates the degradation of HMG-CoA synthase 1 through the Pro/N-degron pathway
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  82. 52.53.155.43 52.53.155.43
    mcr-23-0295-html.html
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      RRID:CVCL_0291

      DOI: 10.1158/1541-7786.mcr-23-0295

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  83. aacrjournals.org aacrjournals.org
    NRAS mutant dictates AHCYL1-governed ER calcium homeostasis for melanoma tumor growth
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  84. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Hippo pathway terminal effector TAZ/WWTR1 mediates oxaliplatin sensitivity in p53 proficient colon cancer cells
    1
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  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Onvansertib in Combination with FOLFIRI and Bevacizumab in Second-line Treatment of KRAS-mutant Metastatic Colorectal Cancer: A Phase 1b Clinical Study
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  86. www.mdpi.com www.mdpi.com
    Systemic DNA Damage and Repair Activity Vary by Race in Breast Cancer Survivors
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      DOI: 10.3390/cancers16101807

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  87. www.sciencedirect.com www.sciencedirect.com
    A novel Senescence-Based prognostic model unveils tumor interactions and drug resistance in colorectal cancer
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      DOI: 10.1016/j.intimp.2024.112197

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  88. 52.53.155.43 52.53.155.43
    Pathway metabolite ratios reveal distinctive glutamine metabolism in a subset of proliferating cells
    2
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      DOI: 10.1101/2024.02.18.580900

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  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Synergy of EGFR and AURKA Inhibitors in KRAS-mutated Non–small Cell Lung Cancers
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      DOI: 10.1158/2767-9764.CRC-23-0482

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  90. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  91. 52.53.155.43 52.53.155.43
    2024.04.30.591961v1.full-html.html
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      DOI: 10.1101/2024.04.30.591961

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  92. 52.53.155.43 52.53.155.43
    SIRT1 mediates the antagonism of Wnt/β-catenin pathway by vitamin D in colon carcinoma cells
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  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Correcting 4sU induced quantification bias in nucleotide conversion RNA-seq data
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  94. Apr 2024
  95. www.sciencedirect.com www.sciencedirect.com
    Exploiting a subtype-specific mitochondrial vulnerability for successful treatment of colorectal peritoneal metastases
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  96. www.embopress.org www.embopress.org
    The regulatory relationship between NAMPT and PD-L1 in cancer and identification of a dual-targeting inhibitor
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  97. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Type I interferon regulation by USP18 is a key vulnerability in cancer
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  98. www.sciencedirect.com www.sciencedirect.com
    A p85 isoform switch enhances PI3K activation on endosomes by a MAP4- and PI3P-dependent mechanism
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  99. www.embopress.org www.embopress.org
    RAD51 restricts DNA over-replication from re-activated origins
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  100. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Early recovery of proteasome activity in cells pulse-treated with proteasome inhibitors is independent of DDI2
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  101. www.sciencedirect.com www.sciencedirect.com
    Global, site-resolved analysis of ubiquitylation occupancy and turnover rate reveals systems properties
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  102. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
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  103. www.sciencedirect.com www.sciencedirect.com
    SRRM2 phase separation drives assembly of nuclear speckle subcompartments
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      ATCC CCL-247

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  104. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Discovery of the sEH Inhibitor Epoxykynin as a Potent Kynurenine Pathway Modulator
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      DOI: 10.1021/acs.jmedchem.3c02245

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  105. www.sciencedirect.com www.sciencedirect.com
    The SPATA5-SPATA5L1 ATPase complex directs replisome proteostasis to ensure genome integrity
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  106. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    p53 rapidly restructures 3D chromatin organization to trigger a transcriptional response
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  107. Mar 2024
  108. www.sciencedirect.com www.sciencedirect.com
    Discovery of YAP1/TAZ pathway inhibitors through phenotypic screening with potent anti-tumor activity via blockade of Rho-GTPase signaling
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  109. 52.53.155.43 52.53.155.43
    Eosinophils exhibit a unique transcriptional signature and increased sensitivity to IL-3-induced activation in response to colorectal cancer cells
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  110. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Reduced chemokine C‐C motif ligand 1 expression may negatively regulate colorectal cancer progression at liver metastatic sites
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  111. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Shaping immune landscape of colorectal cancer by cholesterol metabolites
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  112. www.sciencedirect.com www.sciencedirect.com
    A gut-derived hormone regulates cholesterol metabolism
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  113. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tumor acidosis-induced DNA damage response and tetraploidy enhance sensitivity to ATM and ATR inhibitors
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  114. www.embopress.org www.embopress.org
    RAD51 restricts DNA over-replication from re-activated origins
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  115. www.embopress.org www.embopress.org
    RAD51 restricts DNA over-replication from re-activated origins
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  116. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    KRAS silencing impacts chromatin organization and transcriptional activity in colorectal cancer cells
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  117. www.sciencedirect.com www.sciencedirect.com
    CDK-independent role of D-type cyclins in regulating DNA mismatch repair
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  118. www.sciencedirect.com www.sciencedirect.com
    MTOR modulation induces selective perturbations in histone methylation which influence the anti-proliferative effects of mTOR inhibitors
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  119. Feb 2024
  120. 52.53.155.43 52.53.155.43
    Loss of STIM2 in colorectal cancer drives growth and metastasis through metabolic reprogramming and PERK-ATF4 endoplasmic reticulum stress pathway
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  121. www.sciencedirect.com www.sciencedirect.com
    A synergistic two-drug therapy specifically targets a DNA repair dysregulation that occurs in p53-deficient colorectal and pancreatic cancers
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  122. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of a First-in-Class Small Molecule Inhibitor of the eIF4E-RBM38 Complex that Enhances wild-type p53 Protein Translation for Tumor Growth Suppression
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  123. www.sciencedirect.com www.sciencedirect.com
    Specialized replication mechanisms maintain genome stability at human centromeres
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  124. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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  125. onlinelibrary.wiley.com onlinelibrary.wiley.com
    GNAS mutation inhibits growth and induces phosphodiesterase 4D expression in colorectal cancer cell lines
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      DOI: 10.1002/ijc.34865

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  126. www.sciencedirect.com www.sciencedirect.com
    RNF4 prevents genomic instability caused by chronic DNA under-replication
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  127. www.sciencedirect.com www.sciencedirect.com
    SIN3A histone deacetylase action counteracts MUS81 to promote stalled fork stability
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  128. www.mdpi.com www.mdpi.com
    Stratification of Colorectal Patients Based on Survival Analysis Shows the Value of Consensus Molecular Subtypes and Reveals the CBLL1 Gene as a Biomarker of CMS2 Tumours
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  129. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mieap forms membrane-less organelles involved in cardiolipin metabolism
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  130. link.springer.com link.springer.com
    Functionalized tetrahedral DNA frameworks for the capture of circulating tumor cells
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  131. www.sciencedirect.com www.sciencedirect.com
    Locus-level L1 DNA methylation profiling reveals the epigenetic and transcriptional interplay between L1s and their integration sites
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  132. www.sciencedirect.com www.sciencedirect.com
    Anti-tumor immunotherapy using engineered bacterial outer membrane vesicles fused to lysosome-targeting chimeras mediated by transferrin receptor
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  133. www.mdpi.com www.mdpi.com
    Locked Nucleic Acid Oligonucleotides Facilitate RNA•LNA-RNA Triple-Helix Formation and Reduce MALAT1 Levels
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  134. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Autophagy-dependent alternative splicing of ribosomal protein S24 produces a more stable isoform that aids in hypoxic cell survival
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  135. Jan 2024
  136. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A critical threshold of MCM10 is required to maintain genome stability during differentiation of induced pluripotent stem cells into natural killer cells
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  137. www.nature.com www.nature.com
    Non-alcoholic fatty liver disease promotes liver metastasis of colorectal cancer via fatty acid synthase dependent EGFR palmitoylation
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  138. www.cell.com www.cell.com
    p53-responsive CMBL reprograms glucose metabolism and suppresses cancer development by destabilizing phosphofructokinase PFKP
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  139. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MIIP downregulation drives colorectal cancer progression through inducing peri-cancerous adipose tissue browning
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  140. www.sciencedirect.com www.sciencedirect.com
    Histone lactylation inhibits RARγ expression in macrophages to promote colorectal tumorigenesis through activation of TRAF6-IL-6-STAT3 signaling
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  141. www.sciencedirect.com www.sciencedirect.com
    Discovery of galectin-8 as an LILRB4 ligand driving M-MDSCs defines a class of antibodies to fight solid tumors
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  142. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The effector program of human CD8 T cells supports tissue remodeling
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    Tolerance to colibactin correlates with homologous recombination proficiency and resistance to irinotecan in colorectal cancer cells
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    A comprehensive clinically informed map of dependencies in cancer cells and framework for target prioritization
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  145. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SARS-CoV-2 NSP14 MTase activity is critical for inducing canonical NF-κB activation
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  146. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The feedback loop of EFTUD2/c-MYC impedes chemotherapeutic efficacy by enhancing EFTUD2 transcription and stabilizing c-MYC protein in colorectal cancer
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  147. Dec 2023
  148. www.sciencedirect.com www.sciencedirect.com
    Metabolic regulation of homologous recombination repair by MRE11 lactylation
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  149. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting Aggressive B-cell Lymphomas through Pharmacological Activation of the Mitochondrial Protease OMA1
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  150. www.sciencedirect.com www.sciencedirect.com
    Irreversible inhibition of TRF2TRFH recruiting functions by a covalent cyclic peptide induces telomeric replication stress in cancer cells
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    Proteomic characterization of the colorectal cancer response to chemoradiation and targeted therapies reveals potential therapeutic strategies
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  152. www.tandfonline.com www.tandfonline.com
    Identification of putative allosteric inhibitors of BCKDK via virtual screening and biological evaluation
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  153. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RPF2 mediates the CARM1‑MYCN axis to promote chemotherapy resistance in colorectal cancer cells
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  154. pubs.acs.org pubs.acs.org
    Selective Tumor Hypoxia Targeting Using M75 Antibody Conjugated Photothermally Active MoOx Nanoparticles
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      DOI: 10.1021/acsomega.3c01934

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  155. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Transcript CD81-215 may be a long noncoding RNA of stromal origin with tumor-promoting role in colon cancer
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  156. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Metastatic or xenograft colorectal cancer induce divergent anabolic deficits and pro-inflammatory effectors of muscle wasting in a tumor-type dependent manner
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  157. www.nature.com www.nature.com
    Revealing the tumor suppressive sequence within KL1 domain of the hormone Klotho
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  158. www.biorxiv.org www.biorxiv.org
    A novel antagonist of the CCL5/CCR5 axis suppresses the tumor growth and metastasis of triple-negative breast cancer by CCR5-YAP1 regulation
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  159. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Revisiting the role of endogenous STAT3 in HPV-positive cervical cancer cells
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  160. Nov 2023
  161. www.sciencedirect.com www.sciencedirect.com
    RNF14-dependent atypical ubiquitylation promotes translation-coupled resolution of RNA-protein crosslinks
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  162. www.sciencedirect.com www.sciencedirect.com
    Targeted perturbation of signaling-driven condensates
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  163. link.springer.com link.springer.com
    Cell-specific modulation of mitochondrial respiration and metabolism by the pro-apoptotic Bcl-2 family members Bax and Bak
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  164. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Multiple cullin-associated E3 ligases regulate cyclin D1 protein stability
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      DOI: 10.7554/eLife.80327

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    Anti-tumor effect of PD-L1-targeting antagonistic aptamer-ASO delivery system with dual inhibitory function in immunotherapy
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    HRS mediates tumor immune evasion by regulating proteostasis-associated interferon pathway activation
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    Deficiency of BCAT2-mediated branched-chain amino acid catabolism promotes colorectal cancer development
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    Gasdermin D permeabilization of mitochondrial inner and outer membranes accelerates and enhances pyroptosis
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    TCOF1 promotes the colorectal cancer progression by stabilizing β-catenin
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    In vivo bioluminescence imaging of labile iron in xenograft models and liver using FeAL-1, an iron-activatable form of D-luciferin
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  171. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Matrix stiffness triggers lipid metabolic crosstalk between tumor and stromal cells to mediate bevacizumab resistance in colorectal cancer liver metastases
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  172. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    USP1 Expression Driven by EWS::FLI1 Transcription Factor Stabilizes Survivin and Mitigates Replication Stress in Ewing Sarcoma
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  173. aacrjournals.org aacrjournals.org
    MRTX1719 Is an MTA-Cooperative PRMT5 Inhibitor That Exhibits Synthetic Lethality in Preclinical Models and Patients with MTAP-Deleted Cancer
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    Targeting intracellular oncoproteins with dimeric IgA promotes expulsion from the cytoplasm and immune-mediated control of epithelial cancers
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    The intrinsically disordered region of eIF5B stimulates IRES usage and nucleates biological granule formation
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    BRD4-binding enhancer promotes CRC progression by interacting with YY1 to activate the Wnt pathway through upregulation of TCF7L2
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  178. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    WIP1 is a novel specific target for growth hormone action
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  179. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Cancer-associated FBXW7 loss is synthetic lethal with pharmacological targeting of CDC7
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    Studying the Association of TKS4 and CD2AP Scaffold Proteins and Their Implications in the Partial Epithelial–Mesenchymal Transition (EMT) Process
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  181. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Complementary CRISPR screen highlights the contrasting role of membrane-bound and soluble ICAM-1 in regulating antigen-specific tumor cell killing by cytotoxic T cells
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  182. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Spatial Profiling of Circular RNAs in Cancer Reveals High Expression in Muscle and Stromal Cells
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  183. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    High-content microscopy reveals a morphological signature of bortezomib resistance
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  185. 52.53.155.43 52.53.155.43
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  186. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Piperlongumine is a ligand for the orphan nuclear receptor 4A1 (NR4A1)
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    Targeting Solid Cancers with a Cancer-Specific Monoclonal Antibody to Surface Expressed Aberrantly O-glycosylated Proteins
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    The identification of high-performing antibodies for Coiled-coil-helix-coiled-coil-helix domain containing protein 10 (CHCHD10) for use in Western Blot, immunoprecipitation and immunofluorescence
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    Natural killer cell therapy targeting cancer stem cells: Old wine in a new bottle
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  192. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Epigenomic analysis reveals a unique DNA methylation program of metastasis-competent circulating tumor cells in colorectal cancer
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    The autophagic protein FYCO1 controls TNFRSF10/TRAIL receptor induced apoptosis and is inactivated by CASP8 (caspase 8)
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  194. 52.53.155.43 52.53.155.43
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  195. Aug 2023
  196. www.sciencedirect.com www.sciencedirect.com
    exo-FISH: Protocol for detecting DNA breaks in repetitive regions of mammalian genomes
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    Nuclear transport surveillance of p53 by nuclear pores in glioblastoma
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  198. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MHC Class II is Induced by IFNγ and Follows Three Distinct Patterns of Expression in Colorectal Cancer Organoids
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  200. aacrjournals.org aacrjournals.org
    Vincristine Enhances the Efficacy of MEK Inhibitors in Preclinical Models of KRAS-mutant Colorectal Cancer
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  201. elifesciences.org elifesciences.org
    Vitamin D induces SIRT1 activation through K610 deacetylation in colon cancer
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    DPPA3-HIF1α axis controls colorectal cancer chemoresistance by imposing a slow cell-cycle phenotype
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  203. Jul 2023
  204. 52.53.155.43 52.53.155.43
    British J Pharmacology - 2023 - Cheng - Pharmacological targeting of Axin2 suppresses cell growth and metastasis in-html.html
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