367 Matching Annotations
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    mTORC1 activity suppresses ferroptosis through a SCARB1-dependent HDL-tocopherol uptake pathway
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  4. Mar 2026
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    Targeting PI3Kδ suppresses pancreatic cancer by dual disruption of fibrosis and immune evasion
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    A convergent uPAR-positive tumor ecosystem creates broad vulnerability to CAR T cell therapy
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    CRISPR-Drug Combinatorial Screening Identifies Effective Combination Treatments for MTAP-deleted cancer
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    Cancer cell-derived sialylated IgG interacting with Siglec-7/9/10 is a potential immunotherapeutic target in pancreatic cancer
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    Wild-type RAS signaling is an essential therapeutic target in RAS-mutated cancers
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    GlycoChat Uncovers Glycan–Lectin Circuits in the Tumor Microenvironment of Pancreatic Cancer
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  11. Feb 2026
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    Placing purines in precision medicine: Targeting a metabolic reliance in KRAS-mutant tumors
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    ADT-030, a novel PDE10 inhibitor, demonstrates potent antitumor activity in pancreatic ductal adenocarcinoma
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    Extracellular matrix sensing regulates intratumoral heterogeneity of autophagic flux
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  19. pubs.acs.org pubs.acs.org
    5′-NucA-SMCC-DM1 and 5′-NucA-SPDMV-DM1 are Potent Aptamer–Drug Conjugates against Pancreatic Cancer
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    Synthesis of Benzopyrans and Quinolines with Nitrogenated Chain and Their Cytotoxicity Against Human Cancer Cell Lines
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  22. Jan 2026
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    Simultaneous targeting of KRAS and CDK4 synergistically induces durable growth arrest in pancreatic cancer cells
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  34. Dec 2025
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  49. Nov 2025
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  55. Oct 2025
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    Plakophilin 3 drives acinar cell transformation and promotes cancer initiation and progression in pancreas
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    Defining the MYC-regulated transcriptome and kinome that support KRAS- and ERK-dependent growth of pancreatic cancer
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  64. Sep 2025
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    STYK1 as a targetable vulnerability enhances the efficacy of anti-PD-L1 therapy in pancreatic cancer
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    Loss of Sorting Nexin 10 accelerates KRAS-induced pancreatic tumorigenesis
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    Targeting the IRS1 macromolecular signaling node by Trienomycin a triggers cytoprotective autophagy in pancreatic adenocarcinoma
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    Stress and obesity signaling converge on CREB phosphorylation to promote pancreatic cancer
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  74. Aug 2025
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    SP1-Mediated Glycolytic Reprogramming Promotes Tumorigenesis and Progression in Pancreatic Cancer
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    Inhibition of tumor cell macropinocytosis driver DHODH reverses immunosuppression and overcomes anti-PD1 resistance
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    ADRA2A promotes the classical/progenitor subtype and reduces disease aggressiveness of pancreatic cancer
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    NSD2 inhibitors rewire chromatin to treat lung and pancreatic cancers
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    Integrated real-time imaging of executioner caspase dynamics, apoptosis-induced proliferation, and immunogenic cell death using a stable fluorescent reporter platform
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    A pan-KRAS inhibitor and its derived degrader elicit multifaceted anti-tumor efficacy in KRAS-driven cancers
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    Pathway metabolite ratios reveal distinctive glutamine metabolism in a subset of proliferating cells
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    The urokinase receptor/uPAR is a major effector of p53 gain-of-function mutations in gemcitabine-treated pancreatic ductal adenocarcinoma
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    KRAS-driven pancreatic ductal adenocarcinoma cell lines harbour putative cancer stem cells
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  88. Jul 2025
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    Therapeutic targeting of syndecan-1 axis overcomes acquired resistance to KRAS-targeted therapy in gastrointestinal cancers
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    The role of RAB GTPases in predicting prognosis and therapy response in pancreatic cancer
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  195. Jan 2024
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  207. Dec 2023
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  214. Nov 2023
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  218. Oct 2023
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  223. Sep 2023
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