419 Matching Annotations
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  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    o-carborane encapsulated into polymeric micelles for proton boron capture therapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC13679845/
  3. Oct 2026
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Coenzyme A mitigates cystine-deprivation-induced ferroptosis by suppressing the iron-starvation response
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    pmc.ncbi.nlm.nih.gov/articles/PMC12993722/
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    Multi-Omics and Computational Pharmacology Approach With Experimental Validation Reveals the Antiproliferative Activity of Sophoricoside Against Pancreatic Cancer
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    onlinelibrary.wiley.com/doi/full/10.1002/cbdv.71778
  6. Sep 2026
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    Lack of tumor-derived LCN2 sensitizes pancreatic cancer cells to ferroptosis induction
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    sciencedirect.com/science/article/pii/S0304383526005872
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    HRAS promotes mutant NRAS–driven transformation with codon and allele specificity
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    science.org/doi/10.1126/scisignal.aej6209
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    ARNTL2 promotes metastatic phenotypes through SERPINE1 transcription in KRAS G12D pancreatic cancer
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    sciencedirect.com/science/article/pii/S2589004226028580
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    Targeting PRMT5 inhibitor-induced adaptation in pancreatic cancer with the RBM39 degrader indisulam
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    pmc.ncbi.nlm.nih.gov/articles/PMC13530115/
  11. Aug 2026
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mitophagy-Competent Cancer-Associated Fibroblasts Fuel Chemoresistance by Rewiring Pyrimidine Metabolism in Pancreatic Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13473869/
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    Targeting addiction to HMGB2-driven transcriptional programs in pancreatic cancer
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    sciencedirect.com/science/article/pii/S2211124726007278
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    Engineered mechanosensitive MSCs enable synthetic radiotheranostic targeting across tumor types
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    sciencedirect.com/science/article/pii/S1934590926002754
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    Chrysosplenetin-induced TMED3 aggregation triggers unfolded protein response in pancreatic cancer
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    link.springer.com/article/10.1038/s44321-026-00506-5
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ERO1L induces macrophage infiltration to potentiate KrasG12D and inflammation-induced pancreatic tumorigenesis via oxidative protein folding of CCL2
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    pmc.ncbi.nlm.nih.gov/articles/PMC13479891/
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A Scalable MNase-seq Framework for Reproducible Nucleosome Profiling across Pluripotent Stem Cell and Cardiomyocyte Models
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    pmc.ncbi.nlm.nih.gov/articles/PMC13438036/
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    A stress-adaptive lipid kinase axis defines metabolic vulnerabilities in neuroendocrine prostate cancer
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    sciencedirect.com/science/article/pii/S1535610826003120
  19. Jul 2026
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Acquisition of resistance to RAS inhibition is associated with the upregulation of macropinocytosis through both PI3K-dependent and -independent signaling
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    pmc.ncbi.nlm.nih.gov/articles/PMC13410306/
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    A single-component optogenetic toolkit for reversible visualization and programmable control of microtubule dynamics
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  22. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    <fc>MicroRNA</fc>‐15a/16 regulate protein metabolism and are associated with clinical outcomes in pancreatic ductal adenocarcinoma
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    physoc.onlinelibrary.wiley.com/doi/10.14814/phy2.71015
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    Mitochondria-targeted metformin analogs activate the ER stress-unfolded protein response pathway to drive apoptosis in pancreatic cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13372815/
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    ATM Deficiency Induces TGFβ-Mediated Stromal Programming in Pancreatic Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13370118/
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Defining the MYC-regulated transcriptome and kinome that support KRAS- and ERK-dependent growth of pancreatic cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13343314/
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Inhibiting Fatty Acid Oxidation Reverses Autophagy-Mediated Acquired Chemotherapy Resistance in Pancreatic Ductal Adenocarcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC13324344/
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    Single-Cell and Multiomics Characterization of p21 in Cancer Progression and Therapeutic Sensitivity
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    onlinelibrary.wiley.com/doi/10.1155/humu/5598948
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    Exosomal microRNA-4800-3p in portal vein blood promotes liver metastasis in pancreatic cancer by targeting PLAA
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    nature.com/articles/s41598-026-48779-7
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    Extracellular ATP-P2RY2 signaling drives intratumoral prostaglandin E2 accumulation and adaptive resistance to immunotherapy in solid tumors
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  30. 54.241.53.176 54.241.53.176
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  31. Jun 2026
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    Mutant KRAS-driven selective mRNA translation reveals mechanisms and therapeutic vulnerabilities in cancer
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    The CD49b (ITGA2) collagen receptor excludes CD8+ T cell infiltration in pancreatic ductal adenocarcinoma
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    sciencedirect.com/science/article/pii/S2589004226018754
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    Overcoming adaptive resistance to KRASG12D blockade in pancreatic cancer through vertical pathway inhibition
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    aacrjournals.org/clincancerres/article/32/11/2279/785357/Overcoming-Adaptive-Resistance-to-KRASG12D
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    Pancreatic cancer organoids recapitulate chemotherapy response and identify a potent cytotoxic T cell population
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    aacrjournals.org/clincancerres/article/32/3/596/772037/Pancreatic-Cancer-Organoids-Recapitulate
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    A malignant subpopulation of H2AFZ+ cells interacts with myeloid cells to promote an anti-inflammatory microenvironment and drive hepatic metastasis, revealing an immunotherapeutic strategy for pancreatic ductal adenocarcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC13266339/
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    Mapping cell type-resolved transcriptomic profiles to patient survival in pancreatic cancer
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  39. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Protein Phosphatase Inhibitor LB100 Targets the Mesenchymal Lineage of Pancreatic Ductal Adenocarcinoma
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    Targeting HAS2 to enhance anti-tumor immunity in pancreatic cancer via PD-L1 regulation
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    pmc.ncbi.nlm.nih.gov/articles/PMC13237160/
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    SLC22A3/OCT3 drives serotonin-mediated stemness in pancreatic cancer
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    Diet-induced phospholipid remodeling dictates ferroptosis sensitivity and tumorigenesis in the pancreas
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    Pyrazolo-quinolinone suppresses epithelial–mesenchymal transition by targeting the CXCR4/NF-κB axis in human pancreatic cancer cells
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    sciencedirect.com/science/article/pii/S0344033826002001
  44. May 2026
  45. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Tumor-Derived LAMB3 Drives Immunosuppressive LRRC15+ Fibroblast Formation During Pancreatic Ductal Adenocarcinoma Development
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    advanced.onlinelibrary.wiley.com/doi/full/10.1002/advs.202520029
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    The Host Cell Factor Phosphatase-2A Subunit PR130 Restricts Replication of Herpes Simplex Virus Type-1
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    Integrative multi-omics analysis identifies ATAD1 as a potential regulator of metastasis in pancreatic cancer
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  48. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Multiomics and Genomic Alteration Characterization Identifies VDAC1 as a Mitochondrial‐Associated Biomarker in Pancreatic Cancer
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  49. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RBM15-Mediated m6A Modification Regulates Proliferation and Migration of Pancreatic Cancer Cells via the lncRNA LINC01320/miR-1287-5p/FBXO11 Axis
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    CFIm25-dependent alternative polyadenylation in AKT2 mRNA programs macrophage polarization
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    sciencedirect.com/science/article/pii/S2589004226011661
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    Vorinostat Potentiates Chemoimmunotherapy in Immune-Enriched Pancreatic Cancer
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    advanced.onlinelibrary.wiley.com/doi/full/10.1002/advs.202521844
  52. Apr 2026
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    Engineering functionality-optimized fully human B7-H3 CAR T cells for enhanced solid tumor therapy
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    GLIS3 marks a neural-like progenitor cell state that drives metastasis in pancreatic ductal adenocarcinoma
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    sciencedirect.com/science/article/pii/S221112472600392X
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    The Vitamin D3 Analog Calcipotriol Attenuates Pancreatic Cancer Malignancy via Downregulating Thrombospondin 1 in Pancreatic Stellate Cells
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    onlinelibrary.wiley.com/doi/10.1155/mi/2632235
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  57. www.biorxiv.org www.biorxiv.org
    Mutant KRAS promotes NF-κB driven CCL20 chemokine expression in pancreatic ductal adenocarcinoma
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    biorxiv.org/content/10.64898/2026.04.13.717530v1
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    Loss of Regulator of G protein signaling 11 promotes pro-tumorigenic features in pancreatic cancer
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    mTORC1 activity suppresses ferroptosis through a SCARB1-dependent HDL-tocopherol uptake pathway
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  61. Mar 2026
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    Targeting PI3Kδ suppresses pancreatic cancer by dual disruption of fibrosis and immune evasion
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    A convergent uPAR-positive tumor ecosystem creates broad vulnerability to CAR T cell therapy
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  64. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CRISPR-Drug Combinatorial Screening Identifies Effective Combination Treatments for MTAP-deleted cancer
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    Cancer cell-derived sialylated IgG interacting with Siglec-7/9/10 is a potential immunotherapeutic target in pancreatic cancer
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    Wild-type RAS signaling is an essential therapeutic target in RAS-mutated cancers
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  67. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    GlycoChat Uncovers Glycan–Lectin Circuits in the Tumor Microenvironment of Pancreatic Cancer
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  68. Feb 2026
  69. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Placing purines in precision medicine: Targeting a metabolic reliance in KRAS-mutant tumors
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    An Insulin-Exosome-TNFAIP8 Axis Drives Stromal Fibrosis and Therapeutic Resistance in Pancreatic Cancer
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    advanced.onlinelibrary.wiley.com/doi/full/10.1002/advs.202515606
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    Syndecan-1-targeted therapeutic antibody impairs macropinocytosis and elicits antitumor immunity in pancreatic cancer
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    ADT-030, a novel PDE10 inhibitor, demonstrates potent antitumor activity in pancreatic ductal adenocarcinoma
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    biorxiv.org/content/10.64898/2026.02.11.705411v1
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    Extracellular matrix sensing regulates intratumoral heterogeneity of autophagic flux
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    SERPINA3 mediates liver cancer cells escape from chemotherapy-induced neutrophil extracellular trap killing
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  76. pubs.acs.org pubs.acs.org
    5′-NucA-SMCC-DM1 and 5′-NucA-SPDMV-DM1 are Potent Aptamer–Drug Conjugates against Pancreatic Cancer
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    pubs.acs.org/doi/full/10.1021/acsomega.5c11364
  77. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Covalent modification of a glutamic acid inspired by HaloTag technology
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  78. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Synthesis of Benzopyrans and Quinolines with Nitrogenated Chain and Their Cytotoxicity Against Human Cancer Cell Lines
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  79. Jan 2026
  80. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CK2-mediated HDAC5 shuttling regulates DNA end resection through Ku70 deacetylation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12846757/
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    Dual targeting of SLC25A51 and succinate dehydrogenase selectively depletes mitochondrial NAD+ to eradicate KRAS-driven AML
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    sciencedirect.com/science/article/pii/S155041312600001X
  82. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Simultaneous targeting of KRAS and CDK4 synergistically induces durable growth arrest in pancreatic cancer cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12847887/
  83. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Combined action of suicide gene exosomes from pancreatic cancer-associated fibroblasts and from mesenchymal stem cells as a pancreatic ductal adenocarcinoma treatment approach
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    pmc.ncbi.nlm.nih.gov/articles/PMC12831315/
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    Systematic annotation of orphan RNAs reveals blood-accessible molecular barcodes of cancer identity and cancer-emergent oncogenic drivers
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    sciencedirect.com/science/article/pii/S2666379125006500
  85. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Circ72309 modulates gemcitabine metabolism and gemcitabine sensitivity in pancreatic cancer: Serum Circ72309 levels as a potential predictor of treatment response
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    pmc.ncbi.nlm.nih.gov/articles/PMC12823056/
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    Basroparib inhibits YAP-driven cancers by stabilizing angiomotin
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.70209
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    Multimodal profiling of pancreatic cancer reveals a TIMP-1-dominated secretory profile determining pro-tumor immunoinstruction in human cancers
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    Metabolic Reprogramming of T Cells by Dual UCP2 and IL-17 Blockade Enhances Immunity Against Pancreatic Cancer
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    advanced.onlinelibrary.wiley.com/doi/full/10.1002/advs.202513020
  89. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting a Glutamic Acid in PDEδ with Fluoromethyl-Aryl Electrophiles Impairs K-Ras Signaling
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    pmc.ncbi.nlm.nih.gov/articles/PMC12833852/
  90. www.nature.com www.nature.com
    SLC6A14-mediated glutamine promotes SYTL4–CXCL8 axis activation to drive gemcitabine resistance and immune evasion in pancreatic cancer
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    nature.com/articles/s12276-025-01596-w
  91. Dec 2025
  92. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    Mitochondrial VHL rewires cell metabolism in hypoxia
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    Anti-mitotic agent SB-216 overcomes taxane resistance in castration-resistant prostate cancer and exhibits anti-tumour efficacy in pancreatic cancer
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  188. Dec 2024
  189. www.cell.com www.cell.com
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  191. aacrjournals.org aacrjournals.org
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  192. Nov 2024
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  196. Oct 2024
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  198. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  201. Sep 2024
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  206. Aug 2024
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  215. Jul 2024
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  220. Jun 2024
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  223. May 2024
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