217 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Role of Ca2+‐Dependent Epithelial‐Mesenchymal Transition in Malignant Progression of Colorectal Cancer: Special Focus on REG Iα/EDNRB
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    pmc.ncbi.nlm.nih.gov/articles/PMC13072048/
  3. Apr 2026
  4. aacrjournals.org aacrjournals.org
    TUB-040, a Homogeneous and Hydrophilic NaPi2b-Targeting ADC with Stably Linked Exatecan, Exhibits Long-lasting Antitumor Activity and a Well-Tolerated Safety Profile
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    aacrjournals.org/mct/article/24/11/1685/766863/TUB-040-a-Homogeneous-and-Hydrophilic-NaPi2b
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13042376/
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    AURKA-mediated destabilization of SAPS3 drives ferroptosis evasion via 7-dehydrocholesterol biosynthesis in colorectal cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13039981/
  7. Mar 2026
  8. www.sciencedirect.com www.sciencedirect.com
    A convergent uPAR-positive tumor ecosystem creates broad vulnerability to CAR T cell therapy
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    sciencedirect.com/science/article/pii/S0092867426002692
  9. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    ETV4 Promotes Colorectal Cancer Progression by Reprogramming Asparagine Metabolism to Remodel the Stromal Microenvironment
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202516557
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    Early-stage multi-cancer detection through a plasma extracellular vesicle protein signature
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    sciencedirect.com/science/article/pii/S2666379126001114
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    Engineered pistol ribozymes selectively target KRAS G12V with enhanced efficacy by capping modification
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    sciencedirect.com/science/article/pii/S2451945626000711
  12. www.science.org www.science.org
    Amino acid supplementation enhances in vivo efficacy of lipid nanoparticle–mediated mRNA delivery in preclinical models
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    science.org/doi/10.1126/scitranslmed.adx4097
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    Nigakinone enhances FXR expression to synergize with irinotecan in suppressing colorectal cancer cells and xenografts
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    sciencedirect.com/science/article/pii/S0006295226002376
  14. Feb 2026
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    KRASG12V/HLA-A*02:01–targeted chimeric antigen receptor T cells exhibit potent preclinical activity against solid tumors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12922744/
  16. www.science.org www.science.org
    KRASG12V/HLA-A*02:01–targeted chimeric antigen receptor T cells exhibit potent preclinical activity against solid tumors
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    science.org/doi/10.1126/sciadv.aea2511
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Discovery of novel coumarin-containing triazolo[1,5-a]pyrimidine derivatives as potent ABCB1 inhibitor for modulation of multidrug resistance
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    pmc.ncbi.nlm.nih.gov/articles/PMC12922422/
  18. www.tandfonline.com www.tandfonline.com
    Discovery of novel coumarin-containing triazolo[1,5-a]pyrimidine derivatives as potent ABCB1 inhibitor for modulation of multidrug resistance
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    tandfonline.com/doi/abs/10.1080/14756366.2026.2629074
  19. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    A comprehensive review of anti-colorectal cancer alkaloids from traditional Chinese medicine: Sources, chemical structures, mechanisms and therapeutic applications
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.70343
  20. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Colorectal cancer-derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.70212
  21. Jan 2026
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Thimerosal Inhibits Tumor Malignant Progression through Direct Action and Enhancing the Efficacy of PD-1-Based Immunotherapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12848756/
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    USP10-mediated deubiquitination and activation of KRAS mutants promotes colorectal cancer via a novel USP10/KRAS positive feedback circuit
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    pmc.ncbi.nlm.nih.gov/articles/PMC12827889/
  24. www.sciencedirect.com www.sciencedirect.com
    Systematic annotation of orphan RNAs reveals blood-accessible molecular barcodes of cancer identity and cancer-emergent oncogenic drivers
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    sciencedirect.com/science/article/pii/S2666379125006500
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A single-cell derived spheroid approach to dissect intratumoural heterogeneity in colorectal cancer: cell lines show changes in proteomes and therapeutic response to 5-FU
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    pmc.ncbi.nlm.nih.gov/articles/PMC12831780/
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Expanding the payload scope in antibody-drug conjugates by delivery of hydroxy-containing drugs through self-immolative phosphoramidates
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    pmc.ncbi.nlm.nih.gov/articles/PMC12820277/
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    Basroparib inhibits YAP-driven cancers by stabilizing angiomotin
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.70209
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Immune gene diversity and STING1 variants in shaping cancer immunity across different genetic ancestry populations
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    pmc.ncbi.nlm.nih.gov/articles/PMC13019158/
  29. www.biorxiv.org www.biorxiv.org
    A Novel miR-4745-KLC2 Axis Regulates Cancer Stem Cell Traits in Colorectal Cancer
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    biorxiv.org/content/10.64898/2026.01.07.697660v2
  30. www.jstage.jst.go.jp www.jstage.jst.go.jp
    IFI6 Downregulation Reverses Oxaliplatin Resistance of Colorectal Cancer Cells by Activating the ROS-Induced p38MAPK Signaling Pathway
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    jstage.jst.go.jp/article/bpb/46/1/46_b22-00439/_html/-char/en
  31. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Itaconate‐Related Gene Signatures as Prognostic Markers in Colon Cancer: Insights From Transcriptomic and Spatial Analysis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12790287/
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    Cathepsin-D-mediated MHC class I degradation contributes to immune evasion in colorectal cancer
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  33. Dec 2025
  34. www.sciencedirect.com www.sciencedirect.com
    A TRIM21–UCHL3–ITCH–SIPA1 axis promotes colorectal cancer growth and metastasis
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    sciencedirect.com/science/article/pii/S0304383525007931
  35. www.nature.com www.nature.com
    KRT81 promotes metastasis of colorectal cancer by acting as a protein scaffold for ezrin
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    nature.com/articles/s41388-025-03665-w
  36. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RAS mutation–specific responses to paralog- and state-selective RAS inhibitors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12710464/
  37. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Machine learning-based development of a cytotoxicity prediction model for NK cell therapy in cancers
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  38. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Colorectal Cancer Cell's Weapon: RNF32 Engages SPP1+ Macrophages to Foster Liver Metastasis, Targeted by Indole-3-Acetic Acid
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202519735
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    Nuclear translocation of Cx43 promotes to CRC progression and associates with β-catenin accumulation
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    Genome-Wide CRISPR Screen Reveals PIK3CA Inhibition Enhances Lipid Nanoparticle-Mediated siRNA Delivery
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202517617
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    Single-cell glycome and transcriptome profiling enabled by a library of anti-glycan antibodies
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    Targeting WEE1 in ARID1A/TP53 Concurrent Mutant Colorectal Cancer by Exploiting R-Loop Accumulation and DNA Repair Deficiencies
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202512074
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  44. Nov 2025
  45. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A Citrate Synthase Splice Variant Rewires the TCA Cycle to Promote Colorectal Cancer Progression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12616247/
  46. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    USP10-mediated deubiquitination and activation of KRAS mutants promotes colorectal cancer via a novel USP10/KRAS positive feedback circuit
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    pmc.ncbi.nlm.nih.gov/articles/PMC12827889/
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    CDC7 stabilized by KRAS signaling reactivation impairs chemosensitivity in KRAS-mutant colorectal cancer
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    sciencedirect.com/science/article/pii/S1043661825004529
  48. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Cytoplasmic HMGB1 promotes and interacts with BECN1 through ZNF460 to induce autophagy and accelerate radioresistance in colorectal cancer cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12558843/
  49. Oct 2025
  50. www.sciencedirect.com www.sciencedirect.com
    Hotspot mutant p53-R273H enhances mitochondrial biogenesis and cell migration in primary colorectal cancer in response to oxaliplatin
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    sciencedirect.com/science/article/pii/S0167488925001788
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    Purinergic Ecto-Enzyme CD73 is a Context-Dependent Tumor Suppressor in Colorectal Cancer
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    sciencedirect.com/science/article/pii/S0021925825027164
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    Development of the FGFR4-ADC bearing the ferroptosis inducer sulfasalazine for hepatocellular carcinoma
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    sciencedirect.com/science/article/pii/S2589004225019790
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    Phase separation of circCHD6-encoded 216aa protein promotes colorectal cancer metastasis
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    sciencedirect.com/science/article/pii/S0141813025089792
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    Optimized arenaviruses with tumor-tropic mutations promote safe anti-tumor efficacy via sustainable immune modulatory properties
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    sciencedirect.com/science/article/pii/S2666379125004847
  55. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Role of NOL3 in Colon Adenocarcinoma Metastasis and Its Association With DNA Methylation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12488313/
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    CD169+ macrophages identify and eliminate tumor cells in colorectal cancer through CD169/CD43 interaction and FasL-driven apoptosis
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    sciencedirect.com/science/article/pii/S2211124725011222
  57. Sep 2025
  58. www.biorxiv.org www.biorxiv.org
    Dual EZH1/2 inhibition enhances DNMT inhibitor efficacy in colon cancer through targeting H3K27me1
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    biorxiv.org/content/10.1101/2025.09.16.676613v1
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    Cetuximab increases LGR5 expression and augments LGR5-targeting antibody-drug conjugate efficacy in patient-derived colorectal cancer models
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    A rapid imaging-based screen for induced-proximity degraders identifies a potent degrader of oncoprotein SKP2
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    nature.com/articles/s41587-025-02793-8
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    Knockdown of translocon-associated protein subunit beta (TRAPβ) stimulates cell cycle arrest and apoptosis in human colorectal cancer cells
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  62. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Antibody-Drug Conjugates Targeting the EGFR Ligand Epiregulin Elicit Robust Anti-Tumor Activity in Colorectal Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11875910/
  63. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Wnt10b signaling regulates replication stress–induced chromosomal instability in human cancer
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    A covalent inhibitor targeting Cys16 on RhoA in colorectal cancer
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    sciencedirect.com/science/article/pii/S2451945625002557
  65. Aug 2025
  66. www.sciencedirect.com www.sciencedirect.com
    YTHDF proteins and m6A-RNA clients undergo autophagic turnover during contact inhibition
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    Tissue-dependent mechanosensing by cells derived from human tumors
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  68. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Transcript PHF19-207 May Be a Long Non-Coding RNA with Tumor-Promoting Role in Colon Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12292646/
  69. Jul 2025
  70. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A novel MIR100HG transcript enhances tumorigenesis by inducing BCLAF1-mediated alternative splicing in colorectal cancer
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  71. pubs.acs.org pubs.acs.org
    Mediator Kinase Inhibitor Selectivity and Activity in Colorectal Cancer
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    pubs.acs.org/doi/full/10.1021/acschembio.5c00338
  72. www.biorxiv.org www.biorxiv.org
    Cetuximab increases LGR5 expression and augments LGR5-targeting antibody-drug conjugate efficacy in patient-derived colorectal cancer models
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    biorxiv.org/content/10.1101/2025.06.18.660406v1
  73. Jun 2025
  74. www.cell.com www.cell.com
    BAG2 releases SAMD4B upon sensing of arginine deficiency to promote tumor cell survival
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    cell.com/molecular-cell/fulltext/S1097-2765(25)00499-X
  75. 52.53.155.43 52.53.155.43
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    Hyperacute response proteins synthesized on γ-tubulin-FTO-MARK4 translation microdomains regulate cancer’s acute stress response
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  77. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Modulating autophagy in KRAS mutant colorectal cancer using combination of oncolytic reovirus and carbamazepine
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    pmc.ncbi.nlm.nih.gov/articles/PMC12173229/
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    Ribosomal RNA transcription regulates splicing through ribosomal protein RPL22
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    sciencedirect.com/science/article/pii/S2451945625001734
  79. May 2025
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    Generation of T cell responses against broad KRAS hotspot neoantigens for cell therapy or TCR discovery
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    sciencedirect.com/science/article/pii/S2667237525000852
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    Integrative proteomic profiling of tumor and plasma extracellular vesicles identifies a diagnostic biomarker panel for colorectal cancer
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  82. Apr 2025
  83. www.sciencedirect.com www.sciencedirect.com
    A new EGFR and c-Met bispecific NIR-II fluorescent probe for visualising colorectal cancer and metastatic lymph nodes
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    sciencedirect.com/science/article/pii/S2352396425001318
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    Streptomycin targets tumor-initiating cells by disrupting oxidative phosphorylation
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  86. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    N6-methyladenosine in DNA promotes genome stability
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    pmc.ncbi.nlm.nih.gov/articles/PMC11975372/
  87. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    An Aurora kinase A-BOD1L1-PP2A B56 axis promotes chromosome segregation fidelity
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    pmc.ncbi.nlm.nih.gov/articles/PMC11962599/
  88. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Augmenting CAR T Cell Functions with LIGHT
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    pmc.ncbi.nlm.nih.gov/articles/PMC11444887/
  89. Mar 2025
  90. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ORMDL3 restrains type I interferon signaling and anti-tumor immunity by promoting RIG-I degradation
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    pmc.ncbi.nlm.nih.gov/articles/PMC11932694/
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    Integrated computational analysis identifies therapeutic targets with dual action in cancer cells and T cells
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  92. Feb 2025
  93. 52.53.155.43 52.53.155.43
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    The integrative genomic and functional immunological analyses of colorectal cancer initiating cells to modulate stemness properties and the susceptibility to immune responses
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    link.springer.com/article/10.1186/s12967-025-06176-0
  95. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Identification of Lipid Species Signatures in FOLFOXIRI-Resistant Colorectal Cancer Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC11818583/
  96. aacrjournals.org aacrjournals.org
    Serotonin receptor HTR2B facilitates colorectal cancer metastasis via CREB1-ZEB1 axis mediated epithelial-mesenchymal transition
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    aacrjournals.org/mcr/article/22/6/538/745428/Serotonin-Receptor-HTR2B-Facilitates-Colorectal
  97. Jan 2025
  98. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Missense Mutant p53 Transactivates Wnt/β-Catenin Signaling in Neighboring p53-Destabilized Cells through the COX-2/PGE2 Pathway
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