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Development of the FGFR4-ADC bearing the ferroptosis inducer sulfasalazine for hepatocellular carcinoma

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1. scibot 23 Oct 2025
  
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  RRID:CVCL_0547
  
  DOI: 10.1016/j.isci.2025.113718
  
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sciencedirect.com/science/article/pii/S2589004225019790
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Phase separation of circCHD6-encoded 216aa protein promotes colorectal cancer metastasis

1
1. scibot 22 Oct 2025
  
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  RRID:CVCL_0547
  
  DOI: 10.1016/j.ijbiomac.2025.148422
  
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sciencedirect.com/science/article/pii/S0141813025089792
Oct 2025
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Optimized arenaviruses with tumor-tropic mutations promote safe anti-tumor efficacy via sustainable immune modulatory properties

1
1. scibot 15 Oct 2025
  
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  ATCCCCL-227
  
  DOI: 10.1016/j.xcrm.2025.102411
  
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sciencedirect.com/science/article/pii/S2666379125004847
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The Role of NOL3 in Colon Adenocarcinoma Metastasis and Its Association With DNA Methylation

1
1. scibot 03 Oct 2025
  
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  RRID: CVCL_0547
  
  DOI: 10.1155/humu/9983517
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12488313/
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CD169+ macrophages identify and eliminate tumor cells in colorectal cancer through CD169/CD43 interaction and FasL-driven apoptosis

1
1. scibot 01 Oct 2025
  
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  RRID:CVCL_0547
  
  DOI: 10.1016/j.celrep.2025.116351
  
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sciencedirect.com/science/article/pii/S2211124725011222
Sep 2025
www.biorxiv.org www.biorxiv.org

Dual EZH1/2 inhibition enhances DNMT inhibitor efficacy in colon cancer through targeting H3K27me1

1
1. scibot 25 Sep 2025
  
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  CCL-227
  
  DOI: 10.1101/2025.09.16.676613
  
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biorxiv.org/content/10.1101/2025.09.16.676613v1
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Cetuximab increases LGR5 expression and augments LGR5-targeting antibody-drug conjugate efficacy in patient-derived colorectal cancer models

1
1. scibot 19 Sep 2025
  
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  RRID:CVCL_0547
  
  DOI: 10.1016/j.xcrm.2025.102363
  
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sciencedirect.com/science/article/pii/S2666379125004367
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A rapid imaging-based screen for induced-proximity degraders identifies a potent degrader of oncoprotein SKP2

1
1. scibot 16 Sep 2025
  
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  CVCL_0547
  
  DOI: 10.1038/s41587-025-02793-8
  
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nature.com/articles/s41587-025-02793-8
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Knockdown of translocon-associated protein subunit beta (TRAPβ) stimulates cell cycle arrest and apoptosis in human colorectal cancer cells

1
1. scibot 13 Sep 2025
  
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  SW620
  
  DOI: 10.1016/j.bbamcr.2025.120057
  
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sciencedirect.com/science/article/pii/S0167488925001624
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Antibody-Drug Conjugates Targeting the EGFR Ligand Epiregulin Elicit Robust Anti-Tumor Activity in Colorectal Cancer

1
1. scibot 07 Sep 2025
  
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  RRID:CVCL_0547
  
  DOI: 10.1158/0008-5472.CAN-24-0798
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11875910/
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Wnt10b signaling regulates replication stress–induced chromosomal instability in human cancer

1
1. scibot 06 Sep 2025
  
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  RRID:CVCL_0547
  
  DOI: 10.26508/lsa.202503295
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12373720/
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A covalent inhibitor targeting Cys16 on RhoA in colorectal cancer

1
1. scibot 06 Sep 2025
  
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  ATCC#CCL-227
  
  DOI: 10.1016/j.chembiol.2025.08.004
  
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sciencedirect.com/science/article/pii/S2451945625002557
Aug 2025
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YTHDF proteins and m6A-RNA clients undergo autophagic turnover during contact inhibition

1
1. scibot 26 Aug 2025
  
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  ATCCCat# CCL-227
  
  DOI: 10.1016/j.celrep.2025.116188
  
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sciencedirect.com/science/article/pii/S2211124725009593
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Tissue-dependent mechanosensing by cells derived from human tumors

1
1. scibot 12 Aug 2025
  
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  RRID:CVCL_0547
  
  DOI: 10.1038/s44341-025-00023-5
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12328224/
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Transcript PHF19-207 May Be a Long Non-Coding RNA with Tumor-Promoting Role in Colon Cancer

1
1. scibot 11 Aug 2025
  
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  CVCL_0547
  
  DOI: 10.3390/biom15070957
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12292646/
Jul 2025
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A novel MIR100HG transcript enhances tumorigenesis by inducing BCLAF1-mediated alternative splicing in colorectal cancer

1
1. scibot 10 Jul 2025
  
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  RRID: CVCL_0547
  
  DOI: 10.1186/s12964-025-02280-2
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12239510/
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Mediator Kinase Inhibitor Selectivity and Activity in Colorectal Cancer

1
1. scibot 10 Jul 2025
  
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  RRID:CVCL_0547
  
  DOI: 10.1021/acschembio.5c00338
  
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pubs.acs.org/doi/full/10.1021/acschembio.5c00338
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Cetuximab increases LGR5 expression and augments LGR5-targeting antibody-drug conjugate efficacy in patient-derived colorectal cancer models

1
1. scibot 01 Jul 2025
  
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  RRID:CVCL_0547
  
  DOI: 10.1101/2025.06.18.660406
  
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biorxiv.org/content/10.1101/2025.06.18.660406v1
Jun 2025
www.cell.com www.cell.com

BAG2 releases SAMD4B upon sensing of arginine deficiency to promote tumor cell survival

1
1. scibot 28 Jun 2025
  
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  CCL-227
  
  DOI: 10.1016/j.molcel.2025.05.035
  
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cell.com/molecular-cell/fulltext/S1097-2765(25)00499-X
52.53.155.43 52.53.155.43

1-s2.0-S0367326X25003375-main-html.html

1
1. scibot 28 Jun 2025
  
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  RRID:CVCL_0547
  
  DOI: 10.1016/j.fitote.2025.106711
  
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52.53.155.43/d8b709647df477082238a2d5eeb9b6f7bbcfb2a8/1-s2.0-S0367326X25003375-main-html.html
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Hyperacute response proteins synthesized on γ-tubulin-FTO-MARK4 translation microdomains regulate cancer’s acute stress response

1
1. scibot 18 Jun 2025
  
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  ATCCSW620
  
  DOI: 10.1016/j.celrep.2025.115871
  
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sciencedirect.com/science/article/pii/S2211124725006424
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Modulating autophagy in KRAS mutant colorectal cancer using combination of oncolytic reovirus and carbamazepine

1
1. scibot 18 Jun 2025
  
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  RRID:CVCL_0547
  
  DOI: 10.1371/journal.pone.0326029
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12173229/
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Ribosomal RNA transcription regulates splicing through ribosomal protein RPL22

1
1. scibot 18 Jun 2025
  
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  RRID:CVCL_0547
  
  DOI: 10.1016/j.chembiol.2025.05.012
  
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sciencedirect.com/science/article/pii/S2451945625001734
May 2025
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Generation of T cell responses against broad KRAS hotspot neoantigens for cell therapy or TCR discovery

1
1. scibot 17 May 2025
  
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  RRID:CVCL_0547
  
  DOI: 10.1016/j.crmeth.2025.101049
  
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sciencedirect.com/science/article/pii/S2667237525000852
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Integrative proteomic profiling of tumor and plasma extracellular vesicles identifies a diagnostic biomarker panel for colorectal cancer

1
1. scibot 16 May 2025
  
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  ATCCCat# CCL-227
  
  DOI: 10.1016/j.xcrm.2025.102090
  
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sciencedirect.com/science/article/pii/S2666379125001636
Apr 2025
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A new EGFR and c-Met bispecific NIR-II fluorescent probe for visualising colorectal cancer and metastatic lymph nodes

1
1. scibot 19 Apr 2025
  
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  RRID:CVCL_0547
  
  DOI: 10.1016/j.ebiom.2025.105687
  
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sciencedirect.com/science/article/pii/S2352396425001318
52.53.155.43 52.53.155.43

1-s2.0-S2589004225006649-main-html.html

1
1. scibot 17 Apr 2025
  
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  CVCL_0547
  
  DOI: 10.1016/j.isci.2025.112403
  
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52.53.155.43/869e4b9b9322674b551e8e0015c64383b52b9e33/1-s2.0-S2589004225006649-main-html.html
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Streptomycin targets tumor-initiating cells by disrupting oxidative phosphorylation

1
1. scibot 10 Apr 2025
  
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  ATCCCat#CCL-227
  
  DOI: 10.1016/j.chembiol.2025.03.008
  
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sciencedirect.com/science/article/pii/S2451945625000984
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

N6-methyladenosine in DNA promotes genome stability

1
1. scibot 09 Apr 2025
  
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  RRID:CVCL_0547
  
  DOI: 10.7554/eLife.101626
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11975372/
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An Aurora kinase A-BOD1L1-PP2A B56 axis promotes chromosome segregation fidelity

1
1. scibot 04 Apr 2025
  
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  SW620
  
  DOI: 10.1016/j.celrep.2025.115317
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11962599/
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Augmenting CAR T Cell Functions with LIGHT

1
1. scibot 02 Apr 2025
  
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  SW620
  
  DOI: 10.1158/2326-6066.CIR-24-0246
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11444887/
Mar 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

ORMDL3 restrains type I interferon signaling and anti-tumor immunity by promoting RIG-I degradation

1
1. scibot 27 Mar 2025
  
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  RRID:CVCL_0547
  
  DOI: 10.7554/eLife.101973
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11932694/
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Integrated computational analysis identifies therapeutic targets with dual action in cancer cells and T cells

1
1. scibot 04 Mar 2025
  
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  RRID:CVCL_0547
  
  DOI: 10.1016/j.immuni.2025.02.007
  
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sciencedirect.com/science/article/pii/S107476132500072X
Feb 2025
52.53.155.43 52.53.155.43

618530-html.html

1
1. scibot 27 Feb 2025
  
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  RRID: CVCL_0547
  
  DOI: 10.1038/s41598-021-92623-z
  
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52.53.155.43/416789ac7df726491b564812e1d36841853b9ba2/Maunscript_BJP_20230110-html.html
link.springer.com link.springer.com

The integrative genomic and functional immunological analyses of colorectal cancer initiating cells to modulate stemness properties and the susceptibility to immune responses

1
1. scibot 20 Feb 2025
  
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  RRID:CVCL_0547
  
  DOI: 10.1186/s12967-025-06176-0
  
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link.springer.com/article/10.1186/s12967-025-06176-0
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Identification of Lipid Species Signatures in FOLFOXIRI-Resistant Colorectal Cancer Cells

1
1. scibot 15 Feb 2025
  
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Serotonin receptor HTR2B facilitates colorectal cancer metastasis via CREB1-ZEB1 axis mediated epithelial-mesenchymal transition

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aacrjournals.org/mcr/article/22/6/538/745428/Serotonin-Receptor-HTR2B-Facilitates-Colorectal
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Missense Mutant p53 Transactivates Wnt/β-Catenin Signaling in Neighboring p53-Destabilized Cells through the COX-2/PGE2 Pathway

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Unraveling the mechanism of microRNA-134 in colon cancer progression: targeting KRAS and PIK3CA for cell cycle control and histone deacetylase regulation.

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IMPDH2 dephosphorylation under FGFR signaling promotes S-phase progression and tumor growth

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Antibody-Drug Conjugates Targeting the EGFR Ligand Epiregulin Elicit Robust Anti-Tumor Activity in Colorectal Cancer

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Enhancing efficacy of the MEK inhibitor trametinib with paclitaxel in KRAS-mutated colorectal cancer

1
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Anti-Colon Cancer Effects of Lysate from Potential Probiotic Yeast Strains Derived from Human Breast Milk

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p53 induces circFRMD4A to suppress cancer development through glycolytic reprogramming and cuproptosis

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B7H6 is the predominant activating ligand driving natural killer cell-mediated killing in patients with liquid tumours: evidence from clinical, in silico, in vitro, and in vivo studies

1
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NK Receptor Signaling Lowers TCR Activation Threshold, Enhancing Selective Recognition of Cancer Cells by TAA-Specific CTLs

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2-Hydroxylation of Fatty Acids Represses Colorectal Tumorigenesis and Metastasis via the YAP Transcriptional Axis

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Enhancing efficacy of the MEK inhibitor trametinib with paclitaxel in KRAS-mutated colorectal cancer

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Comprehensive Proteogenomic Profiling Reveals the Molecular Characteristics of Colorectal Cancer at Distinct Stages of Progression

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BPS Publications

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HTS384 NCI60: The Next Phase of the NCI60 Screen

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The SW480 cell line as a model of resident and migrating colon cancer stem cells

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Vincristine Enhances the Efficacy of MEK Inhibitors in Preclinical Models of KRAS-mutant Colorectal Cancer

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Small-molecule NSC59984 induces mutant p53 degradation through a ROS-ERK2-MDM2 axis in cancer cells

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NAMPT-targeting PROTAC and nicotinic acid co-administration elicit safe and robust anti-tumor efficacy in NAPRT-deficient pan-cancers

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Cell-cell contact-dependent secretion of large-extracellular vesicles from EFNBhigh cancer cells accelerates peritoneal dissemination

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Identification and characterization of TM4SF1+ tumor self-seeded cells

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Potentially functional genetic variants in interferon regulatory factor family genes are associated with colorectal cancer survival

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BPS Publications

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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16397
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CRISPR-Cas9 screening identifies INTS3 as an anti-apoptotic RNA-binding protein and therapeutic target for colorectal cancer

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Exploiting a subtype-specific mitochondrial vulnerability for successful treatment of colorectal peritoneal metastases

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FEBS Press

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Targeting high circDNA2v levels in colorectal cancer induces cellular senescence and elicits an anti-tumor secretome

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FEBS Press

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FEBS Press

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febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13645
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Novel diarylated tacrine derivatives: Synthesis, characterization, anticancer, antiepileptic, antibacterial, and antifungal activities

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onlinelibrary.wiley.com/doi/10.1002/jbt.23706
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Downregulation of ABCC3 activates MAPK signaling through accumulation of deoxycholic acid in colorectal cancer cells

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onlinelibrary.wiley.com/doi/10.1111/cas.16132
Mar 2024
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Discovery of YAP1/TAZ pathway inhibitors through phenotypic screening with potent anti-tumor activity via blockade of Rho-GTPase signaling

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Eosinophils exhibit a unique transcriptional signature and increased sensitivity to IL-3-induced activation in response to colorectal cancer cells

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  DOI: 10.1093/jleuko/qiae063
  
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Reduced chemokine C‐C motif ligand 1 expression may negatively regulate colorectal cancer progression at liver metastatic sites

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FEBS Press

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Feb 2024
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First-in-Human Study with preclinical data of BCL-2/BCL-xL Inhibitor Pelcitoclax in Locally Advanced or Metastatic Solid Tumors

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An improved PDE6D inhibitor combines with Sildenafil to synergistically inhibit KRAS mutant cancer cell growth

1
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Identification and Structural Characterization of a mutant KRAS-G12V specific TCR restricted by HLA-A3

1
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Chemomodulatory Effect of the Marine-Derived Metabolite “Terrein” on the Anticancer Properties of Gemcitabine in Colorectal Cancer Cells

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Human endogenous retrovirus onco-exaptation counters cancer cell senescence through calbindin

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The feedback loop of EFTUD2/c-MYC impedes chemotherapeutic efficacy by enhancing EFTUD2 transcription and stabilizing c-MYC protein in colorectal cancer

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Proteomic characterization of the colorectal cancer response to chemoradiation and targeted therapies reveals potential therapeutic strategies

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Engineering CD276/B7-H3-targeted antibody-drug conjugates with enhanced cancer-eradicating capability

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Transcript CD81-215 may be a long noncoding RNA of stromal origin with tumor-promoting role in colon cancer

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TCOF1 promotes the colorectal cancer progression by stabilizing β-catenin

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In vivo bioluminescence imaging of labile iron in xenograft models and liver using FeAL-1, an iron-activatable form of D-luciferin

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Spatially and Functionally Distinct mTORC1 Entities Orchestrate the Cellular Response to Amino Acid Availability

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Epigenomic analysis reveals a unique DNA methylation program of metastasis-competent circulating tumor cells in colorectal cancer

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AMT-562, a novel HER3-targeting antibody drug conjugate, demonstrates a potential to broaden therapeutic opportunities for HER3-expressing tumors

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DPPA3-HIF1α axis controls colorectal cancer chemoresistance by imposing a slow cell-cycle phenotype

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Flat clathrin lattices are linked to metastatic potential in colorectal cancer

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British J Pharmacology - 2023 - Cheng - Pharmacological targeting of Axin2 suppresses cell growth and metastasis in-html.html

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mct-23-0198-html.html

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618530-html.html

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Jun 2023
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Microsatellite instability states serve as predictive biomarkers for tumors chemotherapy sensitivity

1
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The Natural Alkaloid (-)- N-Hydroxyapiosporamide Suppresses Colorectal Tumor Progression as an NF-κB Pathway Inhibitor by Targeting the TAK1-TRAF6 Complex

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MicroRNA-31 induced by Fusobacterium nucleatum infection promotes colorectal cancer tumorigenesis

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ALKBH1-mediated m1A demethylation of METTL3 mRNA promotes the metastasis of colorectal cancer by downregulating SMAD7 expression

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Overexpression of synaptic vesicle protein Rab GTPase 3C promotes vesicular exocytosis and drug resistance in colorectal cancer cells

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BPS Publications

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Downregulation of iNOS/NO Promotes Epithelial–Mesenchymal Transition and Metastasis in Colorectal Cancer

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Dec 2022
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Increased replication origin firing links replication stress to whole chromosomal instability in human cancer

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High-quality and robust protein quantification in large clinical/pharmaceutical cohorts with IonStar proteomics investigation

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Inhibition of insulin‐like growth factor 2 mRNA‐binding protein 1 sensitizes colorectal cancer cells to chemotherapeutics

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Table 1 Tumor cell lines used to set up common subcutaneous mouse tumor models

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Downregulation of protein kinase C gamma reduces epithelial property and enhances malignant phenotypes in colorectal cancer cells

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Tannic Acid, A Hydrolysable Tannin, Prevents Transforming Growth Factor-β-Induced Epithelial–Mesenchymal Transition to Counteract Colorectal Tumor Growth

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Expression of NMU, PPBP and GNG4 in colon cancer and their influences on prognosis

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Addressing the Enzyme-independent tumor-promoting function of NAMPT via PROTAC-mediated degradation

1
1. scibot 03 Nov 2022
  
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  CCL-227
  
  DOI: 10.1016/j.chembiol.2022.10.007
  
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Oct 2022
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5-Methylcytosine (m5C) modification in peripheral blood immune cells is a novel non-invasive biomarker for colorectal cancer diagnosis

1
1. scibot 07 Oct 2022
  
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  RRID: CVCL_ 0547
  
  DOI: 10.3389/fimmu.2022.967921
  
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Simultaneous Imaging and Therapy Using Epitope-Specific Anti-Epidermal Growth Factor Receptor (EGFR) Antibody Conjugates

1
1. scibot 27 Sep 2022
  
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  RRID:CVCL_0547
  
  DOI: 10.3390/pharmaceutics14091917
  
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Lipidomic profiling of exosomes from colorectal cancer cells and patients reveals potential biomarkers

1
1. scibot 27 Jul 2022
  
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  RRID:CVCL_0547
  
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Long non-coding RNA EVADR induced by Fusobacterium nucleatum infection promotes colorectal cancer metastasis

1
1. scibot 27 Jul 2022
  
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  ATCC CCL-227
  
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Data Driven and Biophysical Insights into the Regulation of Trafficking Vesicles by Extracellular Matrix Stiffness

1
1. scibot 27 Jul 2022
  
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  DOI: 10.1016/j.isci.2022.104721
  
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Aberrant expression and subcellular localization of ECT2 drives colorectal cancer progression and growth

1
1. scibot 06 Jul 2022
  
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  RRID:CVCL_0547
  
  DOI: 10.1158/0008-5472.CAN-20-4218
  
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Jun 2022
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Intracellular complement C5a/C5aR1 stabilizes β-catenin to promote colorectal tumorigenesis

1
1. scibot 02 Jun 2022
  
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  ATCCCat#CCL-227
  
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May 2022
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A myosin chaperone, UNC-45A, is a novel regulator of intestinal epithelial barrier integrity and repair

1
1. scibot 05 May 2022
  
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FILIP1L loss is a driver of aggressive mucinous colorectal adenocarcinoma and mediates cytokinesis defects through PFDN1

1
1. scibot 04 May 2022
  
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  RRID:CVCL_0547
  
  DOI: 10.1158/0008-5472.CAN-21-0897
  
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Apr 2022
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Functional genetic screen identifies ITPR3/calcium/RELB axis as a driver of colorectal cancer metastatic liver colonization

1
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  DOI: 10.1016/j.devcel.2022.04.010
  
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A reversible metabolic stress-sensitive regulation of CRMP2A orchestrates EMT/stemness and increases metastatic potential in cancer

1
1. scibot 16 Mar 2022
  
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  ATCCCCL-227
  
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PTBP3 modulates P53 expression and promotes colorectal cancer cell proliferation by maintaining UBE4A mRNA stability

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1. scibot 21 Feb 2022
  
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  DOI: 10.1038/s41419-022-04564-8
  
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CRAF dimerization with ARAF regulates KRAS-driven tumor growth

2
1. scibot 11 Feb 2022
  
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  CCL-227
  
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  CCL-227
  
  DOI: 10.1016/j.celrep.2022.110351
  
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Dec 2021
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Redox-sensitive cyclophilin A elicits chemoresistance through realigning cellular oxidative status in colorectal cancer

1
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  DOI: 10.1016/j.celrep.2021.110069
  
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Insulin-like Growth Factor Binding Protein-2 (IGFBP2) Is a Key Molecule in the MACC1-Mediated Platelet Communication and Metastasis of Colorectal Cancer Cells

1
1. scibot 01 Dec 2021
  
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  RRID:CVCL_0547
  
  DOI: 10.3390/ijms222212195
  
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Oct 2021
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Glycogen accumulation and phase separation drives liver tumor initiation

1
1. scibot 22 Oct 2021
  
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  RRID:CVCL_0547
  
  DOI: 10.1016/j.cell.2021.10.001
  
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BPS Publications

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1. scibot 16 Oct 2021
  
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  RRID:CVCL_0547
  
  DOI: 10.1111/bph.15606
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15606
Sep 2021
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Systematic discovery and validation of T cell targets directed against oncogenic KRAS mutations

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1. scibot 17 Sep 2021
  
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  DOI: 10.1016/j.crmeth.2021.100084
  
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Aug 2021
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Therapeutic Targeting of Metadherin Suppresses Colorectal and Lung Cancer Progression and Metastasis

1
1. scibot 17 Aug 2021
  
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  DOI: 10.1158/0008-5472.CAN-20-1876
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8026491/
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Follistatin-Like 3 Enhances Invasion and Metastasis via β-Catenin-Mediated EMT and Aerobic Glycolysis in Colorectal Cancer

1
1. scibot 16 Aug 2021
  
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  RRID:CVCL_0547
  
  DOI: 10.3389/fcell.2021.660159
  
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Untitled document

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  DOI: 10.1002/jcp.27359
  
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Oxaliplatin resistance in colorectal cancer enhances TRAIL sensitivity via death receptor 4 upregulation and lipid raft localization

1
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  DOI: 10.7554/eLife.67750
  
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Jul 2021
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Blockade of the LRP16-PKR-NF-κB signaling axis sensitizes colorectal carcinoma cells to DNA-damaging cytotoxic therapy

1
1. scibot 31 Jul 2021
  
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  RRID:CVCL_0547
  
  DOI: 10.7554/eLife.27301
  
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Suppression of p16 Induces mTORC1-Mediated Nucleotide Metabolic Reprogramming

1
1. scibot 29 Jul 2021
  
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  Colon: SW620
  
  DOI: 10.1016/j.celrep.2019.07.084
  
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Salinomycin inhibits epigenetic modulator EZH2 to enhance death receptors in colon cancer stem cells

1
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  DOI: 10.1080/15592294.2020.1789270
  
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May 2021
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Novel functional variants in the Notch pathway and survival of Chinese colorectal cancer

1
1. scibot 20 May 2021
  
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Synergistic antitumor activity of DHA and JQ1 in colorectal carcinoma

1
1. scibot 12 May 2021
  
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Polymer-ritonavir derivate nanomedicine with pH-sensitive activation possesses potent anti-tumor activity in vivo via inhibition of proteasome and STAT3 signaling

1
1. scibot 07 May 2021
  
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  DOI: 10.1016/j.jconrel.2021.03.015
  
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FEBS Press

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  DOI: 10.1002/1878-0261.12953
  
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Apr 2021
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Hypomorph Mutation-Directed Small-Molecule Protein-Protein Interaction Inducers to Restore Mutant SMAD4-Suppressed TGF-β Signaling

2
1. scibot 28 Apr 2021
  
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  RRID:CVCL_0547
  
  DOI: 10.1016/j.chembiol.2020.11.010
  
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Extracellular Vesicle and Particle Biomarkers Define Multiple Human Cancers

1
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  CCL-227
  
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Integrated Omics of Metastatic Colorectal Cancer

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  DOI: 10.1016/j.ccell.2020.08.002
  
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PPP6C negatively regulates oncogenic ERK signaling through dephosphorylation of MEK

1
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  DOI: 10.1016/j.celrep.2021.108928
  
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Bacteria‐derived ferrichrome inhibits tumor progression in sporadic colorectal neoplasms and colitis‐associated cancer

1
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  RRID:CVCL_0547
  
  DOI: 10.1186/s12935-020-01723-9
  
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link.springer.com/article/10.1186/s12935-020-01723-9
bmccancer.biomedcentral.com bmccancer.biomedcentral.com

Super-enhancer-associated long noncoding RNA AC005592.2 promotes tumor progression by regulating OLFM4 in colorectal cancer

1
1. scibot 26 Feb 2021
  
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  RRID:CVCL_0547
  
  DOI: 10.1186/s12885-021-07900-x
  
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bmccancer.biomedcentral.com/article/10.1186/s12885-021-07900-x
Jan 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Polyphenolic Fraction Obtained From Thalassia testudinum Marine Plant and Thalassiolin B Exert Cytotoxic Effects in Colorectal Cancer Cells and Arrest Tumor Progression in a Xenograft Mouse Model

1
1. scibot 07 Jan 2021
  
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  RRID:CVCL_0547
  
  DOI: 10.3389/fphar.2020.592985
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7774314/
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Schistosoma mansoni eggs induce Wnt/β-catenin signaling and activate the protooncogene c-Jun in human and hamster colon

1
1. scibot 05 Jan 2021
  
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  RRID:CVCL_0547
  
  DOI: 10.1038/s41598-020-79450-4
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7758332/
Dec 2020
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Long Non-Coding RNA LINC00239 Functions as a Competitive Endogenous RNA by Sponging microRNA-484 and Enhancing KLF12 Expression to Promote the Oncogenicity of Colorectal Cancer

1
1. scibot 07 Dec 2020
  
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  RRID:CVCL_0547
  
  DOI: 10.2147/OTT.S278582
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7695693/
Oct 2020
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The long noncoding RNA LUCAT1 promotes colorectal cancer cell proliferation by antagonizing Nucleolin to regulate MYC expression

1
1. scibot 29 Oct 2020
  
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  RRID:CVCL_0547
  
  DOI: 10.1038/s41419-020-03095-4
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7584667/
Sep 2020
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New role of the antidepressant imipramine as a Fascin1 inhibitor in colorectal cancer cells

1
1. scibot 23 Sep 2020
  
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  RRID:CVCL_0547
  
  DOI: 10.1038/s12276-020-0389-x
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7062870/
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

BPS Publications

1
1. scibot 14 Sep 2020
  
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  RRID:CVCL_0547
  
  DOI: 10.1111/bph.14981
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.14981
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Low-Dose Vertical Inhibition of the RAF-MEK-ERK Cascade Causes Apoptotic Death of KRAS Mutant Cancers

1
1. scibot 14 Sep 2020
  
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  RRID:CVCL_0547
  
  DOI: 10.1016/j.celrep.2020.107764
  
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sciencedirect.com/science/article/pii/S2211124720307440
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Selective targeting of the TLR4 co-receptor, MD2, prevents colon cancer growth and lung metastasis

1
1. scibot 14 Sep 2020
  
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  RRID:CVCL_0547
  
  DOI: 10.7150/ijbs.39098
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7085228/
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Identification of unique and shared mitochondrial DNA mutations in neurodegeneration and cancer by single-cell mitochondrial DNA structural variation sequencing (MitoSV-seq)

1
1. scibot 13 Sep 2020
  
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  CVCL_0547
  
  DOI: 10.1016/j.ebiom.2020.102868
  
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sciencedirect.com/science/article/pii/S2352396420302437
onlinelibrary.wiley.com onlinelibrary.wiley.com

Therapeutic targeting of soluble CD146/MCAM with the M2J‐1 monoclonal antibody prevents metastasis development and procoagulant activity in CD146‐positive invasive tumors

1
1. scibot 05 Sep 2020
  
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  RRID:CVCL_0547
  
  DOI: 10.1002/ijc.32909
  
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onlinelibrary.wiley.com/doi/10.1002/ijc.32909
onlinelibrary.wiley.com onlinelibrary.wiley.com

Cotargeting BET proteins overcomes resistance arising from PI3K/mTOR blockade‐induced protumorigenic senescence in colorectal cancer

1
1. scibot 04 Sep 2020
  
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  RRID: CVCL_0547
  
  DOI: 10.1002/ijc.33047
  
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onlinelibrary.wiley.com/doi/10.1002/ijc.33047
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Basement Membrane Regulates Fibronectin Organization Using Sliding Focal Adhesions Driven by a Contractile Winch

1
1. scibot 04 Sep 2020
  
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  SW620
  
  DOI: 10.1016/j.devcel.2020.01.007
  
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sciencedirect.com/science/article/pii/S1534580720300083
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

Targeting Endogenous K-RAS for Degradation through the Affinity-Directed Protein Missile System

1
1. scibot 03 Sep 2020
  
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  RRID: CVCL_0547
  
  DOI: 10.1016/j.chembiol.2020.06.012
  
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pubmed.ncbi.nlm.nih.gov/32668202/
Aug 2020
www.nature.com www.nature.com

Zinc-finger antiviral protein acts as a tumor suppressor in colorectal cancer

1
1. scibot 27 Aug 2020
  
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  RRID:CVCL_0547
  
  DOI: 10.1038/s41388-020-01416-7
  
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nature.com/articles/s41388-020-01416-7
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Organoid modelling identifies that DACH1 functions as a tumour promoter in colorectal cancer by modulating BMP signalling

1
1. scibot 21 Aug 2020
  
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  RRID:CVCL_0547
  
  DOI: 10.1016/j.ebiom.2020.102800
  
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sciencedirect.com/science/article/pii/S2352396420301754
cancerres.aacrjournals.org cancerres.aacrjournals.org

CoA Synthase (COASY) mediates radiation resistance via PI3K signaling in rectal cancer

1
1. scibot 14 Aug 2020
  
  in Public
  
  RRID:CVCL_0547
  
  DOI: 10.1158/0008-5472.CAN-19-1161
  
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cancerres.aacrjournals.org/content/80/2/334
Jan 2020
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PTPS Facilitates Compartmentalized LTBP1 S-Nitrosylation and Promotes Tumor Growth under Hypoxia

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:CVCL_0547
  
  DOI: 10.1016/j.molcel.2019.09.018
  
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sciencedirect.com/science/article/pii/S1097276519307233
www.sciencedirect.com www.sciencedirect.com

Ethanol promotes alcohol-related colorectal cancer metastasis via the TGF-β/RUNX3/Snail axis by inducing TGF-β1 upregulation and RUNX3 cytoplasmic mislocalization

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:CVCL_0547
  
  DOI: 10.1016/j.ebiom.2019.11.011
  
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sciencedirect.com/science/article/pii/S2352396419307522
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Genomic and Transcriptomic Determinants of Therapy Resistance and Immune Landscape Evolution during Anti-EGFR Treatment in Colorectal Cancer

1
1. scibot 13 Jan 2020
  
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  RRID:CVCL_0547
  
  DOI: 10.1016/j.ccell.2019.05.013
  
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sciencedirect.com/science/article/pii/S1535610819302557
Apr 2019
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

TP53 drives invasion through expression of its Δ133p53β variant

1
1. scibot 05 Apr 2019
  
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  CVCL-0547
  
  Curator: @gabimpine
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5067115/
Nov 2018
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A Short Tandem Repeat-Enriched RNA Assembles a Nuclear Compartment to Control Alternative Splicing and Promote Cell Survival

1
1. scibot 05 Nov 2018
  
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  RRID:CVCL_0547
  
  Curator: @evieth
  
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sciencedirect.com/science/article/pii/S1097276518307019
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Copy number load predicts outcome of metastatic colorectal cancer patients receiving bevacizumab combination therapy

1
1. scibot 05 Nov 2018
  
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  RRID:CVCL_0547
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6173768/
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The Circadian Clock Regulates Metabolic Phenotype Rewiring Via HKDC1 and Modulates Tumor Progression and Drug Response in Colorectal Cancer

2
1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S235239641830241X
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PAF-Myc-Controlled Cell Stemness Is Required for Intestinal Regeneration and Tumorigenesis

1
1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S1534580718301059
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A Peptide Encoded by a Putative lncRNA HOXB-AS3 Suppresses Colon Cancer Growth

1
1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S1097276517306664
Nov 2017
elifesciences.org elifesciences.org

Affimer proteins are versatile and renewable affinity reagents

1
1. scibot 08 Nov 2017
  
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  CVCL_0547
  
  Curator: @chewbeccax
  
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elifesciences.org/articles/24903
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CHD4 Has Oncogenic Functions in Initiating and Maintaining Epigenetic Suppression of Multiple Tumor Suppressor Genes

1
1. scibot 08 Nov 2017
  
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  SW620
  
  Curator: @kaitlinsung
  
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sciencedirect.com/science/article/pii/S1535610817301605
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Eradication of Tumors through Simultaneous Ablation of CD276/B7-H3-Positive Tumor Cells and Tumor Vasculature

1
1. scibot 08 Nov 2017
  
  in Public
  
  CVCL_0547
  
  Curator: @Zeljana_Babic
  
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sciencedirect.com/science/article/pii/S1535610817301010
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Assessing the mechanism and therapeutic potential of modulators of the human Mediator complex-associated protein kinases

1
1. scibot 08 Nov 2017
  
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  CVCL_0547
  
  Curator: @gabimpine
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5224920/
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Computationally designed high specificity inhibitors delineate the roles of BCL2 family proteins in cancer

1
1. scibot 08 Nov 2017
  
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  CVCL_0547
  
  Curator: @gabimpine
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5127641/

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