326 Matching Annotations
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    GLYATL1 is associated with metabolic and epigenetic changes and with endocrine resistance in luminal breast cancer
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    biorxiv.org/content/10.1101/2025.10.17.682994v1
  3. Oct 2025
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    Inhibition of GSK3 and TSC2 Mediates the Oncogenic Activity of AKT in Hepatocellular Carcinoma
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    Lipid-regulated phosphorylation hierarchy of the T cell receptor tyrosine motifs
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  6. Sep 2025
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    CA-125 as a Biomarker in Renal Medullary Carcinoma: Integrated Molecular Profiling, Functional Characterization, and Prospective Clinical Validation
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    Structural insights into DdCBE in action enable high-precision mitochondrial DNA editing
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    The tumor suppressor CYLD acts as a deubiquitinase for mTOR to constrain its activity
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    UBE2T promotes epithelial-mesenchymal transition and motility in oral cancer cells via induction of IL-6 expression
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    PKN2 is a dependency of the mesenchymal-like cancer cell state
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    NF1 Loss Promotes EGFR Activation and Confers Sensitivity to EGFR Inhibition in NF1 Mutant Melanoma
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    A Pan-RAS Inhibitor with a Unique Mechanism of Action Blocks Tumor Growth and Induces Antitumor Immunity in Gastrointestinal Cancer
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    Evaluating CAR-T cells from neurofibromatosis type 1 (NF1) patients for targeting AXL in malignant peripheral nerve sheath tumors associated with NF1
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    Distinct interaction modes orchestrate the polymerization of ASC PYD and CARD domains into filamentous structures
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    K29-Linked Ubiquitination of Transcription Regulators Controls Cell Proliferation in the Unfolded Protein Response
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  20. Aug 2025
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  28. Jul 2025
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    Loss of Predicted Cell Adhesion Molecule MPZL3 Promotes EMT in Ovarian Cancer
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    Requirement for Cyclin D1 Underlies Cell-Autonomous HIF2 Dependence in Kidney Cancer
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  33. Jun 2025
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    A bedside-to-bench translational analysis of NF1 alterations and CDK4/6 inhibitor resistance in hormone receptor-positive metastatic breast cancer
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  41. May 2025
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    Heat shock factor 2 regulates oncogenic gamma-herpesvirus gene expression by remodeling the chromatin at the ORF50 and BZLF1 promoter
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  50. Apr 2025
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    Human long noncoding RNA VILMIR is induced by major respiratory viral infections and modulates the host interferon response
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  55. Mar 2025
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    Peptide Tags and Domains for Expression and Detection of Mammalian Membrane Proteins at the Cell Surface
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    Both carvedilol and cimetidine alleviate cisplatin-induced nephrotoxicity via downregulating OCT2
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  60. Feb 2025
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  68. Jan 2025
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    ASPSCR1::TFE3 Drives Alveolar Soft Part Sarcoma by Inducing Targetable Transcriptional Programs
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    Targeted localization of the mother centrosome in CD8+ T cells undergoing asymmetric cell division promotes memory formation
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  76. Dec 2024
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    Docetaxel response in BRCA1,p53-deficient mammary tumor cells is affected by Huntingtin and BAP1
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    A Comprehensive Evaluation of the HPV Neutralizing Antibodies in Guangzhou, China: A Comparative Study on Various HPV Vaccines
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    Precise kilobase-scale genomic insertions in mammalian cells using PASTE
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    MYC Drives mRNA Pseudouridylation to Mitigate Proliferation-Induced Cellular Stress during Cancer Development
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    Defining Splicing Factor Requirements for Androgen Receptor Variant Synthesis in Advanced Prostate Cancer
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    Identifying the amino acid domains of ORF59 responsible for interactions with ORF57 and PAN RNA during KSHV lytic replication
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    Structure and mechanism of the RalGAP tumor suppressor complex
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  88. Nov 2024
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    Building Synthetic Biosensors Using Red Blood Cell Proteins
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    Transcriptome-scale RNA-targeting CRISPR screens reveal essential lncRNAs in human cells
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  93. Oct 2024
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    Droplet-based functional CRISPR screening of cell–cell interactions by SPEAC-seq
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  95. Sep 2024
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    AXL inhibition prevents RPA2/CHK1-mediated homologous recombination to increase PARP inhibitor sensitivity in hepatocellular carcinoma
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    Claudin-4 remodeling of nucleus-cell cycle crosstalk maintains ovarian tumor genome stability and drives resistance to genomic instability-inducing agents
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    MND1 and PSMC3IP control PARP inhibitor sensitivity in mitotic cells
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  205. Apr 2023
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    Bromodomain protein BRD8 regulates cell cycle progression in colorectal cancer cells through a TIP60-independent regulation of the pre-RC complex
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    Targeting human mitochondrial NAD(P)+-dependent malic enzyme (ME2) impairs energy metabolism and redox state and exhibits antileukemic activity in acute myeloid leukemia
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    A genome-wide CRISPR screen maps endogenous regulators of PPARG gene expression in bladder cancer
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  210. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of Membrane-expressed CAPRIN-1 as a Novel and Universal Cancer Target, and Generation of a Therapeutic Anti-CAPRIN-1 Antibody TRK-950
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    Primary role of type I interferons for the induction of functionally optimal antigen-specific CD8+ T cells in HIV infection
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  212. Mar 2023
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    Loss of the Volume-regulated Anion Channel Components LRRC8A and LRRC8D Limits Platinum Drug Efficacy
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  216. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    LRP6 Is a Functional Receptor for Attenuated Canine Distemper Virus
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    DAXX adds a de novo H3.3K9me3 deposition pathway to the histone chaperone network
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  218. Feb 2023
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    Single nucleus multiomics identifies ZEB1 and MAFB as candidate regulators of Alzheimer’s disease-specific cis-regulatory elements
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    Transmission of NLRP3-IL-1β Signals in Cerebral Ischemia and Reperfusion Injury: from Microglia to Adjacent Neuron and Endothelial Cells via IL-1β/IL-1R1/TRAF6
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  223. Jan 2023
  224. www.mdpi.com www.mdpi.com
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    ZBTB18 restricts chromatin accessibility and prevents transcriptional adaptations that drive metastasis
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