312 Matching Annotations
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    Distinct interaction modes orchestrate the polymerization of ASC PYD and CARD domains into filamentous structures
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.70242
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    K29-Linked Ubiquitination of Transcription Regulators Controls Cell Proliferation in the Unfolded Protein Response
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    advanced.onlinelibrary.wiley.com/doi/full/10.1002/advs.202509817
  5. Aug 2025
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    Fibroblast bioelectric signaling drives hair growth
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    sciencedirect.com/science/article/pii/S0092867425008578
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    Exploration of oncogenic cooperation between germline variation and somatic mutation in prostate cancer progression
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    biorxiv.org/content/10.1101/2025.08.05.668679v1
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ENHANCED CLEAVAGE OF GENOMIC CCR5 USING CASX2Max
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    pmc.ncbi.nlm.nih.gov/articles/PMC12265720/
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    Integrated real-time imaging of executioner caspase dynamics, apoptosis-induced proliferation, and immunogenic cell death using a stable fluorescent reporter platform
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    pmc.ncbi.nlm.nih.gov/articles/PMC12328661/
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    Systematic screening for functional exon-skipping isoforms using the CRISPR-RfxCas13d system
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    cell.com/cell-systems/fulltext/S2405-4712(25)00184-X
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    Enhanced bioluminescence imaging of tumor cells surviving chemotherapy in a murine model of triple-negative breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12311029/
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    Structure and mechanism of the RalGAP tumor suppressor complex
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    pmc.ncbi.nlm.nih.gov/articles/PMC12311180/
  13. Jul 2025
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    Triglycerides are an important fuel reserve for synapse function in the brain
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    Loss of Predicted Cell Adhesion Molecule MPZL3 Promotes EMT in Ovarian Cancer
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    Massively parallel in vivo Perturb-seq screening
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    Requirement for Cyclin D1 Underlies Cell-Autonomous HIF2 Dependence in Kidney Cancer
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  18. Jun 2025
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    A bedside-to-bench translational analysis of NF1 alterations and CDK4/6 inhibitor resistance in hormone receptor-positive metastatic breast cancer
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    Phase separation of TTBK2 and CEP164 is necessary for ciliogenesis
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    RalGAP complexes control secretion and primary cilia in pancreatic disease
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    Centromeric DNA amplification triggered by viral proteins activates nuclear cGAS
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  26. May 2025
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    Therapeutic targeting of circTNK2 with nanoparticles restores tamoxifen sensitivity and enhances NK cell-mediated immunity in ER-positive breast cancer
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    CKAP5 promotes progression and cisplatin resistance in esophageal squamous cell carcinoma via microtubule-mediated YAP activation
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    High-resolution transcriptional impact of AIRE: effects of pathogenic variants p.Arg257Ter, p.Cys311Tyr, and polygenic risk variant p.Arg471Cys
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  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Heat shock factor 2 regulates oncogenic gamma-herpesvirus gene expression by remodeling the chromatin at the ORF50 and BZLF1 promoter
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    Chromatin modification abnormalities by CHD7 and KMT2C loss promote medulloblastoma progression
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  35. Apr 2025
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    Human long noncoding RNA VILMIR is induced by major respiratory viral infections and modulates the host interferon response
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    Vertical inhibition of p110α/AKT and N‐cadherin enhances treatment efficacy in PIK3CA‐aberrated ovarian cancer cells
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  40. Mar 2025
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    Peptide Tags and Domains for Expression and Detection of Mammalian Membrane Proteins at the Cell Surface
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    The NF1 tumor suppressor regulates PD-L1 and immune evasion in melanoma
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    Both carvedilol and cimetidine alleviate cisplatin-induced nephrotoxicity via downregulating OCT2
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  45. Feb 2025
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    Clonal Lineage Tracing with Somatic Delivery of Recordable Barcodes Reveals Migration Histories of Metastatic Prostate Cancer
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    Downregulation of BASP1 promotes temozolomide resistance in gliomas via epigenetic activation of the FBXO32/NF-κB/MGMT axis
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  53. Jan 2025
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    Cell-free assays reveal that the HIV-1 capsid protects reverse transcripts from cGAS immune sensing
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    ASPSCR1::TFE3 Drives Alveolar Soft Part Sarcoma by Inducing Targetable Transcriptional Programs
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  57. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Rhus Verniciflua Stokes Inhibits PD-1 Expression and Induces Anticancer Effects by Enhancing T Cell Function
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    Claudin-4 stabilizes the genome via nuclear and cell cycle remodeling to support ovarian cancer cell survival
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    Targeted localization of the mother centrosome in CD8+ T cells undergoing asymmetric cell division promotes memory formation
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    Hypoxia-inducible factor-targeting therapy augmented the sensitivity to programmed death ligand-1 blockade by enhancing interferon-γ-induced chemokines in tumor cells
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  61. Dec 2024
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    Docetaxel response in BRCA1,p53-deficient mammary tumor cells is affected by Huntingtin and BAP1
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    A Comprehensive Evaluation of the HPV Neutralizing Antibodies in Guangzhou, China: A Comparative Study on Various HPV Vaccines
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    Precise kilobase-scale genomic insertions in mammalian cells using PASTE
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    MYC Drives mRNA Pseudouridylation to Mitigate Proliferation-Induced Cellular Stress during Cancer Development
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    Defining Splicing Factor Requirements for Androgen Receptor Variant Synthesis in Advanced Prostate Cancer
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    Identifying the amino acid domains of ORF59 responsible for interactions with ORF57 and PAN RNA during KSHV lytic replication
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    Structure and mechanism of the RalGAP tumor suppressor complex
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    Phase separation of chimeric antigen receptor promotes immunological synapse maturation and persistent cytotoxicity
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  73. Nov 2024
  74. pubs.acs.org pubs.acs.org
    Building Synthetic Biosensors Using Red Blood Cell Proteins
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    Altered sphingolipid biosynthetic flux and lipoprotein trafficking contribute to trans-fat-induced atherosclerosis
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    CRISPRi/a screens in human iPSC-cardiomyocytes identify glycolytic activation as a druggable target for doxorubicin-induced cardiotoxicity
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    Transcriptome-scale RNA-targeting CRISPR screens reveal essential lncRNAs in human cells
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  78. Oct 2024
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    Droplet-based functional CRISPR screening of cell–cell interactions by SPEAC-seq
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  80. Sep 2024
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    AXL inhibition prevents RPA2/CHK1-mediated homologous recombination to increase PARP inhibitor sensitivity in hepatocellular carcinoma
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    Breast Cancer Stem Cells Upregulate IRF6 in Stromal Fibroblasts to Induce Stromagenesis
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    Claudin-4 remodeling of nucleus-cell cycle crosstalk maintains ovarian tumor genome stability and drives resistance to genomic instability-inducing agents
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    biorxiv.org/content/10.1101/2024.09.04.611120v1
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    The cellular paraspeckle component SFPQ associates with the viral processivity factor ORF59 during lytic replication of Kaposi's Sarcoma-associated herpesvirus (KSHV)
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    MIG6 loss increased RET inhibitor tolerant persister cells in RET-rearranged non-small cell lung cancer
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    Combinatorial targeting of glutamine metabolism and lysosomal-based lipid metabolism effectively suppresses glioblastoma
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    GABAergic neuronal lineage development determines clinically actionable targets in diffuse hemispheric glioma, H3G34-mutant
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  89. Aug 2024
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    Members of an array of zinc-finger proteins specify distinct Hox chromatin boundaries
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    Casein kinase 1α mediates phosphorylation of the Merkel cell polyomavirus large T antigen for β-TrCP destruction complex interaction and subsequent degradation
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    ABIN1 is a negative regulator of effector functions in cytotoxic T cells
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    Protocol for screening and validating antibodies specific to protein phosphorylation sites using a set of yeast biopanning approaches
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    Replicative senescence is ATM driven, reversible, and accelerated by hyperactivation of ATM at normoxia
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    Activation of the helper NRC4 immune receptor forms a hexameric resistosome
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    Spontaneous and evoked synaptic vesicle release arises from a single releasable pool
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  97. Jul 2024
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    Cetylpyridinium chloride triggers paraptosis to suppress pancreatic tumor growth via the ERN1-MAP3K5-p38 pathway
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    ATAD1 prevents clogging of TOM and damage caused by un-imported mitochondrial proteins
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  203. Feb 2023
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  208. Jan 2023
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    ZBTB18 restricts chromatin accessibility and prevents transcriptional adaptations that drive metastasis
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    LRP6 Is a Functional Receptor for Attenuated Canine Distemper Virus
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    Novel Calcium-Binding Ablating Mutations Induce Constitutive RET Activity and Drive Tumorigenesis
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  217. Dec 2022
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    Clonal transcriptomics identifies mechanisms of chemoresistance and empowers rational design of combination therapies
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    RASopathy mutations provide functional insight into the BRAF cysteine-rich domain and reveal the importance of autoinhibition in BRAF regulation
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    An inhibitor of BRD4, GNE987, inhibits the growth of glioblastoma cells by targeting C-Myc and S100A16
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  225. Sep 2022
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