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204 Matching Annotations

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Dietary saturated fatty acids promote lung myeloid cell inflammasome activation and IL-1β–mediated inflammation in mice and humans

1
1. scibot 04 Sep 2025
  
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  JAX, no. 004781
  
  DOI: 10.1126/scitranslmed.adp5653
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
  Curator: @dhovakimyan1
  
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science.org/doi/10.1126/scitranslmed.adp5653
www.sciencedirect.com www.sciencedirect.com

Tolerance to non-inherited maternal antigen is sustained by LysM+ CD11c+ maternal microchimeric cells

1
1. scibot 03 Sep 2025
  
  in Public
  
  The Jackson LaboratoryStrain Code: 004781
  
  DOI: 10.1016/j.immuni.2025.08.005
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
  Curator: @areedewitt04
  
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sciencedirect.com/science/article/pii/S1074761325003681
Aug 2025
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Macrophages orchestrate elimination of Shigella from the intestinal epithelial cell niche via TLR-induced IL-12 and IFN-γ

1
1. scibot 30 Aug 2025
  
  in Public
  
  RRID:IMSR_JAX:0
  
  DOI: 10.1016/j.chom.2025.08.001
  
  Resource: None
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_JAX:004781
  
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  RRID:IMSR_JAX:004781 RRIDCUR:Unresolved
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sciencedirect.com/science/article/pii/S1931312825002975
Jul 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

TREM2‐Mediated Myeloid Cells Protect Against Pathological Choroidal Neovascularization

1
1. scibot 30 Jul 2025
  
  in Public
  
  RRID:IMSR_JAX:0004781
  
  DOI: 10.1096/fj.202501793R
  
  Resource: None
  
  Curator: @sonofthor
  
  SciCrunch record: RRID:IMSR_JAX:004781
  
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  RRID:IMSR_JAX:004781 RRIDCUR:Unresolved
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pmc.ncbi.nlm.nih.gov/articles/PMC12302306/
www.biorxiv.org www.biorxiv.org

Estrogens protect bone mass by inhibiting NAD+ metabolism in osteoclasts

1
1. scibot 23 Jul 2025
  
  in Public
  
  stock no. 004781
  
  DOI: 10.1101/2025.07.11.664289
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
  Curator: @dhovakimyan1
  
  SciCrunch record: RRID:IMSR_JAX:004781
  
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biorxiv.org/content/10.1101/2025.07.11.664289v1
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The aryl hydrocarbon receptor interacting protein suppresses RNA virus-induced type I IFN and IL-6 in mouse macrophages

1
1. scibot 10 Jul 2025
  
  in Public
  
  strain #004781
  
  DOI: 10.1101/2025.06.30.662398
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
  Curator: @dhovakimyan1
  
  SciCrunch record: RRID:IMSR_JAX:004781
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12236720/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

RORγ Bridges Cancer-Driven Lipid Dysmetabolism and Myeloid Immunosuppression

2
1. scibot 08 Jul 2025
  
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  JAX:004781
  
  DOI: 10.1158/2159-8290.CD-24-0199
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
  Curator: @sonofthor
  
  SciCrunch record: RRID:IMSR_JAX:004781
  
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  RRID:IMSR_JAX:004781
2. scibot 08 Jul 2025
  
  in Public
  
  RRID:IMSR_JAX:004781
  
  DOI: 10.1158/2159-8290.CD-24-0199
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:004781
  
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  RRID:IMSR_JAX:004781
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pmc.ncbi.nlm.nih.gov/articles/PMC12223513/
www.ahajournals.org www.ahajournals.org

Lysozyme 1 Inflamed CCR2+ Macrophages Promote Obesity-Induced Cardiac Dysfunction | Circulation Research

1
1. scibot 04 Jul 2025
  
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  RRID:IMSR_JAX:004781
  
  DOI: 10.1161/CIRCRESAHA.124.324106
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:004781
  
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  RRID:IMSR_JAX:004781
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ahajournals.org/doi/full/10.1161/CIRCRESAHA.124.324106
www.biorxiv.org www.biorxiv.org

Role of Macrophage PARP1 in the Regulation of Crosstalk between Adipose Immune Cells and Adipocytes during Diet-induced Obesity

1
1. scibot 01 Jul 2025
  
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  stock No. 004781
  
  DOI: 10.1101/2025.06.20.660762
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
  Curator: @dhovakimyan1
  
  SciCrunch record: RRID:IMSR_JAX:004781
  
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  RRID:IMSR_JAX:004781
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biorxiv.org/content/10.1101/2025.06.20.660762v1
Jun 2025
www.sciencedirect.com www.sciencedirect.com

Methylglyoxal is an antibacterial effector produced by macrophages during infection

1
1. scibot 24 Jun 2025
  
  in Public
  
  Jackson Laboratory Cat_004781
  
  DOI: 10.1016/j.chom.2025.05.026
  
  Resource: None
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_JAX:004781
  
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  RRID:IMSR_JAX:004781 RRIDCUR:Unresolved
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sciencedirect.com/science/article/pii/S1931312825002094
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Piezo1 senses hyphae and initiates host defense against pathogenic fungi

1
1. scibot 17 Jun 2025
  
  in Public
  
  Jackson LaboratoryStock No:004781
  
  DOI: 10.1016/j.celrep.2025.115839
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_JAX:004781
  
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  RRID:IMSR_JAX:004781
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sciencedirect.com/science/article/pii/S2211124725006102
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EGR2 O-GlcNAcylation orchestrates the development of protumoral macrophages to limit CD8+ T cell antitumor responses

1
1. scibot 11 Jun 2025
  
  in Public
  
  RRID:IMSR_JAX:004781
  
  DOI: 10.1016/j.chembiol.2025.05.007
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:004781
  
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  RRID:IMSR_JAX:004781
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sciencedirect.com/science/article/pii/S2451945625001680
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Distinct TAM subset with cross-dressing capability determines the bifurcation of tumor immunity

1
1. scibot 11 Jun 2025
  
  in Public
  
  RIKEN Animal FacilityStrain #004781
  
  DOI: 10.1016/j.celrep.2025.115800
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_JAX:004781
  
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  RRID:IMSR_JAX:004781
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sciencedirect.com/science/article/pii/S2211124725005716
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Filamin A editing in myeloid cells reduces intestinal inflammation and protects from colitis

1
1. scibot 11 Jun 2025
  
  in Public
  
  RRID:IMSR_JAX:004781
  
  DOI: 10.1084/jem.20240109
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:004781
  
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  RRID:IMSR_JAX:004781
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pmc.ncbi.nlm.nih.gov/articles/PMC12139521/
www.sciencedirect.com www.sciencedirect.com

PGK1 phosphorylates NLRP3 and mediates inflammasome activation independent of its glycolytic activity

1
1. scibot 05 Jun 2025
  
  in Public
  
  004781
  
  DOI: 10.1016/j.celrep.2025.115785
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_JAX:004781
  
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  RRID:IMSR_JAX:004781
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sciencedirect.com/science/article/pii/S221112472500556X
May 2025
dx.doi.org dx.doi.org

Myeloid-specific HNRNPA2B1 deficiency disrupts macrophage function and in vivo responses

1
1. scibot 29 May 2025
  
  in Public
  
  RRID:IMSR_JAX:004781
  
  DOI: 10.1093/jimmun/vkaf073
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:004781
  
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  RRID:IMSR_JAX:004781
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dx.doi.org/10.1093/jimmun/vkaf073
academic.oup.com academic.oup.com

12-Lipoxygenase inhibition improves glycemia and obesity-associated inflammation in male human gene replacement mice

1
1. scibot 22 May 2025
  
  in Public
  
  Jackson Laboratory, strain #004781
  
  DOI: 10.1210/endocr/bqaf069
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
  Curator: @sjvitug
  
  SciCrunch record: RRID:IMSR_JAX:004781
  
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  RRID:IMSR_JAX:004781
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academic.oup.com/endo/article-abstract/166/6/bqaf069/8106702
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Endothelial Nrf2 deficiency promotes atherosclerotic lesion formation by shaping a proinflammatory niche

1
1. scibot 22 May 2025
  
  in Public
  
  The Jackson Laboratory, Strain #:004781
  
  DOI: 10.1016/j.lfs.2025.123725
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_JAX:004781
  
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  RRID:IMSR_JAX:004781
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sciencedirect.com/science/article/pii/S0024320525003601
52.53.155.43 52.53.155.43

PDF-html.html

1
1. scibot 20 May 2025
  
  in Public
  
  JAX:004781
  
  DOI: 10.1101/2025.04.23.649615
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:004781
  
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  RRID:IMSR_JAX:004781
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52.53.155.43/940b43b532f27c10fd5855c1e3772edb393b5559/PDF-html.html
www.sciencedirect.com www.sciencedirect.com

Activation of the endoplasmic reticulum stress regulator IRE1α compromises pulmonary host defenses

1
1. scibot 16 May 2025
  
  in Public
  
  Jackson LaboratoryStock No: 004781
  
  DOI: 10.1016/j.celrep.2025.115632
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_JAX:004781
  
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  RRID:IMSR_JAX:004781
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sciencedirect.com/science/article/pii/S2211124725004036
Apr 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

cGAS and STING in Host Myeloid Cells Are Essential for Effective Cyclophosphamide Treatment of Advanced Breast Cancer

1
1. scibot 19 Apr 2025
  
  in Public
  
  RRID:IMSR_JAX:004781
  
  DOI: 10.3390/cancers17071130
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:004781
  
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  RRID:IMSR_JAX:004781
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pmc.ncbi.nlm.nih.gov/articles/PMC11987962/
www.sciencedirect.com www.sciencedirect.com

Potentiation of macrophage Piezo1 by atherogenic 7-ketocholesterol

1
1. scibot 15 Apr 2025
  
  in Public
  
  The Jackson laboratoryCat#004781
  
  DOI: 10.1016/j.celrep.2025.115542
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_JAX:004781
  
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  RRID:IMSR_JAX:004781
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sciencedirect.com/science/article/pii/S2211124725003134
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Mitochondrial DNA released by senescent tumor cells enhances PMN-MDSC-driven immunosuppression through the cGAS-STING pathway

1
1. scibot 09 Apr 2025
  
  in Public
  
  RRID:IMSR_JAX:004781
  
  DOI: 10.1016/j.immuni.2025.03.005
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:004781
  
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  RRID:IMSR_JAX:004781
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sciencedirect.com/science/article/pii/S1074761325001244
52.53.155.43 52.53.155.43

PDF-html.html

1
1. scibot 02 Apr 2025
  
  in Public
  
  JAX, 004781
  
  DOI: 10.1158/2326-6066.cir-24-0737
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
  Curator: @sjvitug
  
  SciCrunch record: RRID:IMSR_JAX:004781
  
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  RRID:IMSR_JAX:004781
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52.53.155.43/6082e85085e2ed08cbf86aa32472ba192b5c95f0/PDF-html.html
Mar 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Enterobactin inhibits microbiota-dependent activation of AhR to promote bacterial sepsis in mice

1
1. scibot 18 Mar 2025
  
  in Public
  
  RRID:IMSR_JAX:004781
  
  DOI: 10.1038/s41564-024-01882-9
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:004781
  
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  RRID:IMSR_JAX:004781
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pmc.ncbi.nlm.nih.gov/articles/PMC11905502/
www.sciencedirect.com www.sciencedirect.com

Phosphatase PHLPP1 is an alveolar-macrophage-intrinsic transcriptional checkpoint controlling pulmonary fibrosis

1
1. scibot 13 Mar 2025
  
  in Public
  
  RRID:IMSR_JAX:004781
  
  DOI: 10.1016/j.celrep.2025.115399
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:004781
  
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  RRID:IMSR_JAX:004781
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sciencedirect.com/science/article/pii/S2211124725001706
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A heart-brain-spleen axis controls cardiac remodeling to hypertensive stress

1
1. scibot 04 Mar 2025
  
  in Public
  
  RRID:IMSR_JAX:004781
  
  DOI: 10.1016/j.immuni.2025.02.013
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:004781
  
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  RRID:IMSR_JAX:004781
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sciencedirect.com/science/article/pii/S1074761325000809
Feb 2025
aacrjournals.org aacrjournals.org

MerTK Induces Dysfunctional Dendritic Cells by Metabolic Reprogramming

1
1. scibot 20 Feb 2025
  
  in Public
  
  RRID:IMSR_JAX:004781
  
  DOI: 10.1158/2326-6066.CIR-23-0666
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:004781
  
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  RRID:IMSR_JAX:004781
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aacrjournals.org/cancerimmunolres/article/12/9/1268/747083/MerTK-Induces-Dysfunctional-Dendritic-Cells-by
www.sciencedirect.com www.sciencedirect.com

ArfGAP2 promotes STING proton channel activity, cytokine transit, and autoinflammation

1
1. scibot 13 Feb 2025
  
  in Public
  
  RRID:IMSR_JAX:004781
  
  DOI: 10.1016/j.cell.2025.01.027
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:004781
  
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  RRID:IMSR_JAX:004781
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sciencedirect.com/science/article/pii/S0092867425000960
www.sciencedirect.com www.sciencedirect.com

Adiponectin reduces immune checkpoint inhibitor-induced inflammation without blocking anti-tumor immunity

1
1. scibot 11 Feb 2025
  
  in Public
  
  RRID:IMSR_JAX:004781
  
  DOI: 10.1016/j.ccell.2025.01.004
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:004781
  
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  RRID:IMSR_JAX:004781
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sciencedirect.com/science/article/pii/S1535610825000224
Jan 2025
www.sciencedirect.com www.sciencedirect.com

Nuclear adenine activates hnRNPA2B1 to enhance antibacterial innate immunity

1
1. scibot 16 Jan 2025
  
  in Public
  
  The Jackson LaboratoryJAX 004781
  
  DOI: 10.1016/j.cmet.2024.11.014
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_JAX:004781
  
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  RRID:IMSR_JAX:004781
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sciencedirect.com/science/article/pii/S1550413124004820
www.sciencedirect.com www.sciencedirect.com

Metabolic reprogramming of macrophages by PKM2 promotes IL-10 production via adenosine

1
1. scibot 14 Jan 2025
  
  in Public
  
  The JacksonLaboratoryCat# 004781
  
  DOI: 10.1016/j.celrep.2024.115172
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_JAX:004781
  
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  RRID:IMSR_JAX:004781
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52.53.155.43 52.53.155.43

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1. scibot 08 Jan 2025
  
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  004781
  
  DOI: 10.1242/dmm.052012
  
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52.53.155.43/655757fa415bf079eca462bbd3dfdcf1acc316d2/PDF-html.html
Dec 2024
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Long non-coding RNA Malat1 fine-tunes bone homeostasis and repair by orchestrating cellular crosstalk and β-catenin-OPG/Jagged1 pathway

1
1. scibot 27 Dec 2024
  
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  RRID:IMSR_JAX:004781
  
  DOI: 10.7554/eLife.98900
  
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A pan-family screen of nuclear receptors in immunocytes reveals ligand-dependent inflammasome control

1
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  JAX# 004781
  
  DOI: 10.1016/j.immuni.2024.10.010
  
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Cytoplasmic RNA quality control failure engages mTORC1-mediated autoinflammatory disease

1
1. scibot 14 Nov 2024
  
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  004781
  
  DOI: 10.1172/JCI146176
  
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NRG4-ErbB4 signaling represses proinflammatory macrophage activity

1
1. scibot 14 Nov 2024
  
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  004781
  
  DOI: 10.1152/ajpgi.00296.2020
  
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Stored RBC Transfusions Leads to the Systemic Inflammatory Response Syndrome in Anemic Murine Neonates

1
1. scibot 12 Nov 2024
  
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  DOI: 10.1007/s00011-024-01936-y
  
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Itaconate transporter SLC13A3 impairs tumor immunity via endowing ferroptosis resistance

1
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  JAX:004781
  
  DOI: 10.1016/j.ccell.2024.10.010
  
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Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) deletion in myeloid cells augments cholestatic liver injury

1
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  DOI: 10.1038/s41598-024-52710-3
  
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Ablation of PC1/3 in POMC-expressing Tissues but not in Immune Cells Induces Sepsis Hypersensitivity

1
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  RRID:IMSR_JAX:004781
  
  DOI: 10.1210/jendso/bvae171
  
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Notch signaling regulates macrophage-mediated inflammation in metabolic dysfunction-associated steatotic liver disease

1
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  DOI: 10.1016/j.immuni.2024.08.016
  
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Granulocyte colony stimulating factor promotes scarless tissue regeneration

1
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  DOI: 10.1016/j.celrep.2024.114742
  
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PDIA3 defines a novel subset of adipose macrophages to exacerbate the development of obesity and metabolic disorders

1
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  RRID:IMSR_JAX:004781
  
  DOI: 10.1016/j.cmet.2024.08.009
  
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Myeloid-Specific Thrombospondin-1 Deficiency Exacerbates Aortic Rupture via Broad Suppression of Extracellular Matrix Proteins

1
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  RRID:IMSR_JAX:004781
  
  DOI: 10.1101/2024.07.30.605216
  
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Krüppel-like Factor (KLF) family members control expression of genes required for serous cavity and alveolar macrophage identities

1
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  DOI: 10.1101/2024.02.28.582578
  
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Deficiency of macrophage-derived Dnase1L3 causes lupus-like phenotypes in mice

1
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  DOI: 10.1093/jleuko/qiad115
  
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The involvement of neuroimmune cells in adipose innervation

1
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  B6.129P2-Lyz2/J
  
  DOI: 10.1186/s10020-020-00254-3
  
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molmed.biomedcentral.com/article/10.1186/s10020-020-00254-3
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The choroid plexus synergizes with immune cells during neuroinflammation

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  DOI: 10.1016/j.cell.2024.07.002
  
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Kmt2c restricts G-CSF-driven HSC mobilization and granulocyte production in a methyltransferase-independent manner

2
1. scibot 25 Jul 2024
  
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  DOI: 10.1016/j.celrep.2024.114542
  
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  RRID:IMSR_JAX:004781
  
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cir-23-0666-html.html

1
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  RRID:IMSR_JAX:004781
  
  DOI: 10.1158/2326-6066.cir-23-0666
  
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Macrophage memories of early-life injury drive neonatal nociceptive priming

1
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  Jax004781
  
  DOI: 10.1016/j.celrep.2024.114129
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11197107/
May 2024
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Glucose-driven histone lactylation promotes the immunosuppressive activity of monocyte-derived macrophages in glioblastoma

1
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  RRID:IMSR_JAX:004781
  
  DOI: 10.1016/j.immuni.2024.04.006
  
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PAD4 controls tumor immunity via restraining the MHC class II machinery in macrophages

2
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  DOI: 10.1016/j.celrep.2024.113942
  
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Apr 2024
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Membrane-bound O-acyltransferase 7 (MBOAT7) shapes lysosomal lipid homeostasis and function to control alcohol-associated liver injury

1
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  RRID:IMSR_JAX:004781
  
  DOI: 10.7554/eLife.92243
  
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Endothelial cell expression of a STING gain-of-function mutation initiates pulmonary lymphocytic infiltration

1
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  DOI: 10.1016/j.celrep.2024.114114
  
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Squalene-epoxidase-catalyzed 24(S),25-epoxycholesterol synthesis promotes trained-immunity-mediated antitumor activity

2
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  RRID:IMSR_JAX:004781
  
  DOI: 10.1016/j.celrep.2024.114094
  
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  RRID:IMSR_JAX:004781
  
  DOI: 10.1016/j.celrep.2024.114094
  
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LXR/CD38 activation drives cholesterol-induced macrophage senescence and neurodegeneration via NAD+ depletion

1
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  JAX:004781
  
  DOI: 10.1016/j.celrep.2024.114102
  
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Jagged2 targeting in lung cancer activates anti-tumor immunity via Notch-induced functional reprogramming of tumor-associated macrophages

1
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  RRID:IMSR_JAX:004781
  
  DOI: 10.1016/j.immuni.2024.03.020
  
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Peripheral HMGB1 is linked to O3 pathology of disease-associated astrocytes and amyloid

1
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  RRID:IMSR_JAX:004781
  
  DOI: 10.1002/alz.13825
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11095433/
Mar 2024
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A stress sensor, IRE1α, is required for bacterial-exotoxin-induced interleukin-1β production in tissue-resident macrophages

2
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  JAX:004781
  
  DOI: 10.1016/j.celrep.2024.113981
  
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  JAX:004781
  
  DOI: 10.1016/j.celrep.2024.113981
  
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MAFB in macrophages regulates cold-induced neuronal density in brown adipose tissue

1
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  RRID:IMSR_JAX:004781
  
  DOI: 10.1016/j.celrep.2024.113978
  
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sciencedirect.com/science/article/pii/S2211124724003061
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Clinical drug screening reveals clofazimine potentiates the efficacy while reducing the toxicity of anti-PD-1 and CTLA-4 immunotherapy

1
1. scibot 22 Mar 2024
  
  in Public
  
  The Jackson LaboratoryCat#004781
  
  DOI: 10.1016/j.ccell.2024.03.001
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
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www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

RBP-J regulates homeostasis and function of circulating Ly6Clo monocytes

1
1. scibot 19 Mar 2024
  
  in Public
  
  Strain #: 004781 from Jackson Laboratory
  
  DOI: 10.7554/eLife.88135
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
  Curator: @evieth
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10942619/
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Neutrophil-inflicted vasculature damage suppresses immune-mediated optic nerve regeneration

1
1. scibot 19 Mar 2024
  
  in Public
  
  The Jackson LaboratoryStock# 004781
  
  DOI: 10.1016/j.celrep.2024.113931
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
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sciencedirect.com/science/article/pii/S2211124724002596
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PAD4 controls tumor immunity via restraining the MHC class II machinery in macrophages

2
1. scibot 15 Mar 2024
  
  in Public
  
  JAX:004781
  
  DOI: 10.1016/j.celrep.2024.113942
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
  Curator: @scibot
  
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  RRID:IMSR_JAX:004781
2. scibot 15 Mar 2024
  
  in Public
  
  JAX:004781
  
  DOI: 10.1016/j.celrep.2024.113942
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11022165/
Feb 2024
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Downregulation of IRF8 in alveolar macrophages by G-CSF promotes metastatic tumor progression

1
1. scibot 29 Feb 2024
  
  in Public
  
  The Jackson LaboratoryCat#004781
  
  DOI: 10.1016/j.isci.2024.109187
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
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sciencedirect.com/science/article/pii/S2589004224004085
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IgG is an aging factor that drives adipose tissue fibrosis and metabolic decline

1
1. scibot 21 Feb 2024
  
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  RRID:IMSR_JAX:004781
  
  DOI: 10.1016/j.cmet.2024.01.015
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
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sciencedirect.com/science/article/abs/pii/S1550413124000159
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Amphiregulin from regulatory T cells promotes liver fibrosis and insulin resistance in non-alcoholic steatohepatitis

2
1. scibot 06 Feb 2024
  
  in Public
  
  JAX:004781
  
  DOI: 10.1016/j.immuni.2024.01.009
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
  Curator: @scibot
  
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  RRID:IMSR_JAX:004781
2. scibot 06 Feb 2024
  
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  JAX:004781
  
  DOI: 10.1016/j.immuni.2024.01.009
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
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sciencedirect.com/science/article/pii/S1074761324000347
Jan 2024
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Type 2 cytokine signaling in macrophages protects from cellular senescence and organismal aging

1
1. scibot 23 Jan 2024
  
  in Public
  
  The Jackson LaboratoryStrain #004781
  
  DOI: 10.1016/j.immuni.2024.01.001
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
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sciencedirect.com/science/article/pii/S1074761324000268
www.nature.com www.nature.com

Myeloid cell-associated aromatic amino acid metabolism facilitates CNS myelin regeneration

1
1. scibot 05 Jan 2024
  
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  RRID:IMSR_JAX:004781
  
  DOI: 10.1038/s41536-023-00345-9
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
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nature.com/articles/s41536-023-00345-9
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Cooperative sensing of mitochondrial DNA by ZBP1 and cGAS promotes cardiotoxicity

1
1. scibot 04 Jan 2024
  
  in Public
  
  004781
  
  DOI: 10.1016/j.cell.2023.05.039
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
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sciencedirect.com/science/article/pii/S0092867423005913
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Age-associated features of norovirus infection analysed in mice

1
1. scibot 03 Jan 2024
  
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  004781
  
  DOI: 10.1038/s41564-023-01383-1
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
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pmc.ncbi.nlm.nih.gov/articles/PMC10484054/
rupress.org rupress.org

Trained immunity of alveolar macrophages enhances injury resolution via KLF4-MERTK-mediated efferocytosis

1
1. scibot 02 Jan 2024
  
  in Public
  
  004781
  
  DOI: 10.1084/jem.20221388
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
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rupress.org/jem/article/220/11/e20221388/276204/Trained-immunity-of-alveolar-macrophages-enhances
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Myeloid cell-specific deletion of epidermal growth factor receptor aggravates acute cardiac injury

1
1. scibot 02 Jan 2024
  
  in Public
  
  004781
  
  DOI: 10.1042/CS20230804
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
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pmc.ncbi.nlm.nih.gov/articles/PMC10758753/
Dec 2023
www.sciencedirect.com www.sciencedirect.com

Myeloid cell-derived creatine in the hypoxic niche promotes glioblastoma growth

1
1. scibot 22 Dec 2023
  
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  JAX:004781
  
  DOI: 10.1016/j.cmet.2023.11.013
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
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sciencedirect.com/science/article/pii/S155041312300445X
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Reprogramming of tumor-associated macrophages via NEDD4-mediated CSF1R degradation by targeting USP18

1
1. scibot 17 Dec 2023
  
  in Public
  
  RRID:IMSR_JAX:004781
  
  DOI: 10.1016/j.celrep.2023.113560
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
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sciencedirect.com/science/article/pii/S2211124723015723
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Early cellular mechanisms of type I interferon-driven susceptibility to tuberculosis

1
1. scibot 02 Dec 2023
  
  in Public
  
  RRID:IMSR_JAX:004781
  
  DOI: 10.1016/j.cell.2023.11.002
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
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pmc.ncbi.nlm.nih.gov/articles/PMC10757650/
Oct 2023
www.biorxiv.org www.biorxiv.org

The RNA binding protein, HNRNPA2B1, regulates IFNG signaling in macrophages

1
1. scibot 24 Oct 2023
  
  in Public
  
  RRID:IMSR_JAX:004781
  
  DOI: 10.1101/2023.10.12.562050
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
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biorxiv.org/content/10.1101/2023.10.12.562050v1
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Neutrophils resist ferroptosis and promote breast cancer metastasis through aconitate decarboxylase 1

1
1. scibot 13 Oct 2023
  
  in Public
  
  RRID:IMSR_JAX:004781
  
  DOI: 10.1016/j.cmet.2023.09.004
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
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sciencedirect.com/science/article/pii/S1550413123003364
Sep 2023
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Myeloid BAF60a deficiency alters metabolic homeostasis and exacerbates atherosclerosis

1
1. scibot 30 Sep 2023
  
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  JAX:004781
  
  DOI: 10.1016/j.celrep.2023.113171
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
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sciencedirect.com/science/article/pii/S221112472301183X
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Adenosine A2A receptor is a tumor suppressor of NASH-associated hepatocellular carcinoma

1
1. scibot 28 Sep 2023
  
  in Public
  
  RRID:IMSR_JAX:004781
  
  DOI: 10.1016/j.xcrm.2023.101188
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10518627/
Aug 2023
52.53.155.43 52.53.155.43

The miR-23-27-24 clusters drive lipid-associated macrophage proliferation in obese adipose tissue

2
1. scibot 12 Aug 2023
  
  in Public
  
  JAX:004781
  
  DOI: 10.1016/j.celrep.2023.112928
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
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  RRID:IMSR_JAX:004781
2. scibot 05 Aug 2023
  
  in Public
  
  JAX:004781
  
  DOI: 10.1016/j.celrep.2023.112928
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
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52.53.155.43/4a6b7aa5507bdf2becad8c264c3514e078fa27b5/PIIS2211124723009397-html.html
Jul 2023
www.sciencedirect.com www.sciencedirect.com

LYVE-1+ macrophages form a collaborative CCR5-dependent perivascular niche that influences chemotherapy responses in murine breast cancer

1
1. scibot 13 Jul 2023
  
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  RRID:IMSR_JAX:004781
  
  DOI: 10.1016/j.devcel.2023.06.006
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
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sciencedirect.com/science/article/pii/S1534580723003040
Jun 2023
www.biorxiv.org www.biorxiv.org

Autophagy is required to prevent early pro-inflammatory responses and neutrophil recruitment during Mycobacterium tuberculosis infection without affecting pathogen replication in macrophages

1
1. scibot 08 Jun 2023
  
  in Public
  
  Jax #004781
  
  DOI: 10.1101/2022.11.04.515221
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
  Curator: @bandrow
  
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biorxiv.org/content/10.1101/2022.11.04.515221v2
May 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Macrophages regulate gastrointestinal motility through complement component 1q

1
1. scibot 18 May 2023
  
  in Public
  
  Stock #004781
  
  DOI: 10.7554/eLife.78558
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
  Curator: @evieth
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10185340/
Apr 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Neutrophil Conversion to a Tumor-Killing Phenotype Underpins Effective Microbial Therapy

1
1. scibot 21 Apr 2023
  
  in Public
  
  RRID:IMSR_JAX:004781
  
  DOI: 10.1158/0008-5472.CAN-21-4025
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10102850/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

cDC1 coordinate innate and adaptive responses in the omentum required for T cell priming and memory

1
1. scibot 05 Apr 2023
  
  in Public
  
  RRID:IMSR_JAX:004781
  
  DOI: 10.1126/sciimmunol.abq7432
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9835709/
Feb 2023
www.science.org www.science.org

CD47 halts Ptpn6-deficient neutrophils from provoking lethal inflammation

1
1. scibot 07 Feb 2023
  
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  004781
  
  DOI: 10.1126/sciadv.ade3942
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
  Curator: @bandrow
  
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science.org/doi/10.1126/sciadv.ade3942
www.sciencedirect.com www.sciencedirect.com

Renal control of life-threatening malarial anemia

2
1. scibot 03 Feb 2023
  
  in Public
  
  RRID:IMSR_JAX:004781
  
  DOI: 10.1016/j.celrep.2023.112057
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
  Curator: @scibot
  
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  RRID:IMSR_JAX:004781
2. scibot 03 Feb 2023
  
  in Public
  
  RRID:IMSR_JAX:004
  
  DOI: 10.1016/j.celrep.2023.112057
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
  Curator: @sofiakhan13
  
  SciCrunch record: RRID:IMSR_JAX:004781
  
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  RRIDCUR:Unresolved RRID:IMSR_JAX:004781
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sciencedirect.com/science/article/pii/S2211124723000682
Oct 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Cbl-b Restrains Priming of Pathogenic Th17 Cells via the Inhibition of IL-6 Production by Macrophages

1
1. scibot 04 Oct 2022
  
  in Public
  
  RRID:IMSR_JAX:004781
  
  DOI: 10.1016/j.isci.2022.105151
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9523381/
Sep 2022
www.sciencedirect.com www.sciencedirect.com

Combined genetic deletion of GDF15 and FGF21 has modest effects on body weight, hepatic steatosis and insulin resistance in high fat fed mice

1
1. scibot 16 Sep 2022
  
  in Public
  
  RRID:IMSR_JAX:004781
  
  DOI: 10.1016/j.molmet.2022.101589
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
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sciencedirect.com/science/article/pii/S2212877822001582
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Tumor-associated macrophages are shaped by intratumoral high potassium via Kir2.1

1
1. scibot 15 Sep 2022
  
  in Public
  
  JAX:004781
  
  DOI: 10.1016/j.cmet.2022.08.016
  
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onlinelibrary.wiley.com onlinelibrary.wiley.com

Deficiency of Ninjurin1 attenuates LPS/D-galactosamine-induced acute liver failure by reducing TNF-α-induced apoptosis in hepatocytes

1
1. scibot 14 Sep 2022
  
  in Public
  
  RRID:IMSR_JAX:004781
  
  DOI: 10.1111/jcmm.17538
  
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onlinelibrary.wiley.com/doi/full/10.1111/jcmm.17538
Aug 2022
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Adenosine metabolized from extracellular ATP promotes type 2 immunity through triggering A2BAR signaling in intestinal epithelial cells

1
1. scibot 06 Aug 2022
  
  in Public
  
  Jax Strain #004781
  
  DOI: 10.1016/j.celrep.2022.111150
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
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sciencedirect.com/science/article/pii/S2211124722009597
Jun 2022
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The STING1-MYD88 complex drives ACOD1/IRG1 expression and function in lethal innate immunity

1
1. scibot 22 Jun 2022
  
  in Public
  
  The Jackson Laboratory004781
  
  DOI: 10.1016/j.isci.2022.104561
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
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Tet2 deficiency drives liver microbiome dysbiosis triggering Tc1 cell autoimmune hepatitis

1
1. scibot 03 Jun 2022
  
  in Public
  
  Jackson LaboratoryStock No: 004781
  
  DOI: 10.1016/j.chom.2022.05.006
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9841318/
May 2022
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Activation of the transcription factor NRF2 mediates the anti-inflammatory properties of a subset of over-the-counter and prescription NSAIDs

1
1. scibot 19 May 2022
  
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  JAX:004781
  
  DOI: 10.1016/j.immuni.2022.04.015
  
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Macrophage-derived cholesterol contributes to therapeutic resistance in prostate cancer

1
1. scibot 04 May 2022
  
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  JAX 004781
  
  DOI: 10.1158/0008-5472.CAN-20-4028
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8563406/
Apr 2022
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TNF-α sculpts a maturation process in vivo by pruning tolerogenic dendritic cells

1
1. scibot 14 Apr 2022
  
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  Jackson LaboratoryStock# 004781
  
  DOI: 10.1016/j.celrep.2022.110657
  
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sciencedirect.com/science/article/pii/S2211124722004090
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Microbiota-dependent activation of the myeloid calcineurin-NFAT pathway inhibits B7H3- and B7H4-dependent anti-tumor immunity in colorectal cancer

1
1. scibot 01 Apr 2022
  
  in Public
  
  RRID:IMSR_JAX:004781
  
  DOI: 10.1016/j.immuni.2022.03.008
  
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sciencedirect.com/science/article/pii/S1074761322001315
Mar 2022
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Notch-mediated lactate metabolism regulates MDSC development through the Hes1/MCT2/c-Jun axis

1
1. scibot 09 Mar 2022
  
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  JAX:004781
  
  DOI: 10.1016/j.celrep.2022.110451
  
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sciencedirect.com/science/article/pii/S2211124722001784
Feb 2022
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Tryptophan-derived microbial metabolites activate the aryl hydrocarbon receptor in tumor-associated macrophages to suppress anti-tumor immunity

2
1. scibot 11 Feb 2022
  
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  Jax: 004781
  
  DOI: 10.1016/j.immuni.2022.01.006
  
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2. scibot 09 Feb 2022
  
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  Jax: 004781
  
  DOI: 10.1016/j.immuni.2022.01.006
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8888129/
Dec 2021
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Macrophages transfer mitochondria to sensory neurons to resolve inflammatory pain

1
1. scibot 18 Dec 2021
  
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  RRID:IMSR_JAX:004781
  
  DOI: 10.1016/j.neuron.2021.11.020
  
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Inflammatory macrophages exploit unconventional pro-phagocytic integrins for phagocytosis and anti-tumor immunity

1
1. scibot 15 Dec 2021
  
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  Stock No: 004781
  
  DOI: 10.1016/j.celrep.2021.110111
  
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sciencedirect.com/science/article/pii/S2211124721016053
Nov 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Susceptibility rhythm to bacterial endotoxin in myeloid clock-knockout mice

1
1. scibot 24 Nov 2021
  
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  RRID:IMSR_JAX:004781
  
  DOI: 10.7554/eLife.62469
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8598165/
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COMMD10 is critical for Kupffer cell survival and controls Ly6Chi monocyte differentiation and inflammation in the injured liver

1
1. scibot 17 Nov 2021
  
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  Stock No: 004781
  
  DOI: 10.1016/j.celrep.2021.110026
  
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sciencedirect.com/science/article/pii/S2211124721015084
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m6A mRNA methylation-directed myeloid cell activation controls progression of NAFLD and obesity

1
1. scibot 10 Nov 2021
  
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  Stock# 004781
  
  DOI: 10.1016/j.celrep.2021.109968
  
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sciencedirect.com/science/article/pii/S2211124721014479
Oct 2021
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Enteric pathogens induce tissue tolerance and prevent neuronal loss from subsequent infections

1
1. scibot 30 Oct 2021
  
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  004781
  
  DOI: 10.1016/j.cell.2021.10.004
  
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sciencedirect.com/science/article/pii/S0092867421011788
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Myeloid lineage contributes to pathological choroidal neovascularization formation via SOCS3

1
1. scibot 22 Oct 2021
  
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  004781
  
  DOI: 10.1016/j.ebiom.2021.103632
  
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sciencedirect.com/science/article/pii/S2352396421004254
Sep 2021
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Tumor-derived exosomes drive immunosuppressive macrophages in a pre-metastatic niche through glycolytic dominant metabolic reprogramming

1
1. scibot 24 Sep 2021
  
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  Stock#004781
  
  DOI: 10.1016/j.cmet.2021.09.002
  
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sciencedirect.com/science/article/pii/S1550413121004216
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Senescent immune cells release grancalcin to promote skeletal aging

1
1. scibot 14 Sep 2021
  
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  004781
  
  DOI: 10.1016/j.cmet.2021.08.009
  
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sciencedirect.com/science/article/pii/S1550413121003727
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Loss of Mir146b with aging contributes to inflammation and mitochondrial dysfunction in thioglycollate-elicited peritoneal macrophages

1
1. scibot 11 Sep 2021
  
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  RRID:IMSR_JAX:004781
  
  DOI: 10.7554/eLife.66703
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8412946/
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Deoxyhypusine synthase promotes a pro-inflammatory macrophage phenotype

1
1. scibot 08 Sep 2021
  
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  004781
  
  DOI: 10.1016/j.cmet.2021.08.003
  
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sciencedirect.com/science/article/pii/S1550413121003661
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Sepsis expands a CD39+ plasmablast population that promotes immunosuppression via adenosine-mediated inhibition of macrophage antimicrobial activity

1
1. scibot 04 Sep 2021
  
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  Cat#004781
  
  DOI: 10.1016/j.immuni.2021.08.005
  
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sciencedirect.com/science/article/pii/S1074761321003356
Jul 2021
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Epithelial HMGB1 Delays Skin Wound Healing and Drives Tumor Initiation by Priming Neutrophils for NET Formation

1
1. scibot 31 Jul 2021
  
  in Public
  
  Mouse: LysM Cre: B6.129P2-Lyz2tm1(cre)/lfo/J
  
  DOI: 10.1016/j.celrep.2019.10.104
  
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sciencedirect.com/science/article/pii/S2211124719314378
emboj.embopress.org emboj.embopress.org

BRD4 directs hematopoietic stem cell development and modulates macrophage inflammatory responses

1
1. scibot 31 Jul 2021
  
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  RRID:IMSR_JAX:004781
  
  DOI: 10.15252/embj.2018100293
  
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emboj.embopress.org/content/early/2019/03/06/embj.2018100293
academic.oup.com academic.oup.com

Untitled document

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1. scibot 31 Jul 2021
  
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  RRID:IMSR_JAX:004781
  
  DOI: 10.1093/hmg/ddz009
  
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academic.oup.com/hmg/advance-article/doi/10.1093/hmg/ddz009/5280925
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Adrenergic Signaling in Muscularis Macrophages Limits Infection-Induced Neuronal Loss

1
1. scibot 30 Jul 2021
  
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  Jackson Laboratory#004781
  
  DOI: 10.1016/j.cell.2019.12.002
  
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sciencedirect.com/science/article/pii/S0092867419313285
onlinelibrary.wiley.com onlinelibrary.wiley.com

Untitled document

1
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  RRID:IMSR_JAX:004781
  
  DOI: 10.15252/embj.2018100293
  
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onlinelibrary.wiley.com/doi/10.15252/embj.2018100293
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Tissue-Specific Macrophage Responses to Remote Injury Impact the Outcome of Subsequent Local Immune Challenge

2
1. scibot 29 Jul 2021
  
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  JAX: 004781
  
  DOI: 10.1016/j.immuni.2019.10.010
  
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2. scibot 28 Jul 2021
  
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  JAX:004781
  
  DOI: 10.1016/j.immuni.2019.10.010
  
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pmc.ncbi.nlm.nih.gov/articles/PMC6892583/
journals.sagepub.com journals.sagepub.com

Adverse effects of BMPR2 suppression in macrophages in animal models of pulmonary hypertension

1
1. scibot 29 Jul 2021
  
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  004781
  
  DOI: 10.1177/2045894019856483
  
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journals.sagepub.com/doi/pdf/10.1177/2045894019856483
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Untitled document

2
1. scibot 29 Jul 2021
  
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  RRID:IMSR_JAX:004781
  
  DOI: 10.7554/eLife.32497
  
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2. scibot 29 Jul 2021
  
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  RRID:IMSR_JAX:004781
  
  DOI: 10.7554/eLife.32497
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
  Curator: @evieth
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5762159/
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Lymph Node Mesenchymal and Endothelial Stromal Cells Cooperate via the RANK-RANKL Cytokine Axis to Shape the Sinusoidal Macrophage Niche

1
1. scibot 28 Jul 2021
  
  in Public
  
  Mouse: B6.129P2-Lyz2tm1(cre)Ifo/J
  
  DOI: 10.1016/j.immuni.2019.05.008
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
  Curator: @ethanbadger
  
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sciencedirect.com/science/article/pii/S1074761319302286
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DNA methyltransferase 1 and Krüppel-like factor 4 axis regulates macrophage inflammation and atherosclerosis

1
1. scibot 28 Jul 2021
  
  in Public
  
  004781
  
  DOI: 10.1016/j.yjmcc.2019.01.009
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
  Curator: @bandrow
  
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  RRID:IMSR_JAX:004781 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S0022282818308770
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Club cells form lung adenocarcinomas and maintain the alveoli of adult mice

1
1. scibot 28 Jul 2021
  
  in Public
  
  RRID:IMSR_JAX:004781
  
  DOI: 10.7554/eLife.45571
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
  Curator: @scibot
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6606035/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Diabetes reversal by inhibition of the low molecular weight tyrosine phosphatase

1
1. scibot 27 Jul 2021
  
  in Public
  
  004781
  
  DOI: 10.1038/nchembio.2344
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
  Curator: @mpairish
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5435566/
Jun 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Resistance to lethal ectromelia virus infection requires Type I interferon receptor in natural killer cells and monocytes but not in adaptive immune or parenchymal cells

1
1. scibot 17 Jun 2021
  
  in Public
  
  JAX:004781
  
  DOI: 10.1371/journal.ppat.1009593
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
  Curator: @scibot
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8172060/
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MYC-mediated early glycolysis negatively regulates proinflammatory responses by controlling IRF4 in inflammatory macrophages

1
1. scibot 16 Jun 2021
  
  in Public
  
  RRID:IMSR_JAX:004781
  
  DOI: 10.1016/j.celrep.2021.109264
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
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sciencedirect.com/science/article/pii/S2211124721006318
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Cytomegalovirus subverts macrophage identity

1
1. scibot 11 Jun 2021
  
  in Public
  
  RRID:IMSR_JAX:004781
  
  DOI: 10.1016/j.cell.2021.05.009
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
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sciencedirect.com/science/article/pii/S0092867421006267
May 2021
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Western diet induces Paneth cell defects through microbiome alterations and farnesoid X receptor and type I interferon activation

1
1. scibot 19 May 2021
  
  in Public
  
  Cat. # 004781
  
  DOI: 10.1016/j.chom.2021.04.004
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
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sciencedirect.com/science/article/pii/S1931312821001803
www.nature.com www.nature.com

Feeding-induced resistance to acute lethal sepsis is dependent on hepatic BMAL1 and FXR signalling

1
1. scibot 15 May 2021
  
  in Public
  
  RRID:IMSR_JAX:004781
  
  DOI: 10.1038/s41467-021-22961-z
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
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nature.com/articles/s41467-021-22961-z
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Histone Deacetylase 3 Couples Mitochondria to Drive IL-1β-Dependent Inflammation by Configuring Fatty Acid Oxidation

1
1. scibot 07 May 2021
  
  in Public
  
  JAX:004781
  
  DOI: 10.1016/j.molcel.2020.08.015
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
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sciencedirect.com/science/article/pii/S1097276520305785
Apr 2021
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MiR-690, an exosomal-derived miRNA from M2-polarized macrophages, improves insulin sensitivity in obese mice

1
1. scibot 30 Apr 2021
  
  in Public
  
  JAX:004781
  
  DOI: 10.1016/j.cmet.2020.12.019
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S1550413120307178
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Enteric helminth coinfection enhances host susceptibility to neurotropic flaviviruses via a tuft cell-IL-4 receptor signaling axis

1
1. scibot 27 Apr 2021
  
  in Public
  
  Cat # 004781
  
  DOI: 10.1016/j.cell.2021.01.051
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
  Curator: @Naa003
  
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  RRID:IMSR_JAX:004781 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S0092867421000945
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The Intestinal Microbiome Restricts Alphavirus Infection and Dissemination through a Bile Acid-Type I IFN Signaling Axis

1
1. scibot 24 Apr 2021
  
  in Public
  
  RRID:IMSR_JAX:004781
  
  DOI: 10.1016/j.cell.2020.06.029
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
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sciencedirect.com/science/article/pii/S0092867420308060
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Microbiota regulate innate immune signaling and protective immunity against cancer

1
1. scibot 24 Apr 2021
  
  in Public
  
  JAX:004781
  
  DOI: 10.1016/j.chom.2021.03.016
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
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  RRID:IMSR_JAX:004781
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sciencedirect.com/science/article/pii/S193131282100144X
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Hierarchical cell-type-specific functions of caspase-11 in LPS shock and antibacterial host defense

1
1. scibot 21 Apr 2021
  
  in Public
  
  RRID:IMSR_JAX:004781
  
  DOI: 10.1016/j.celrep.2021.109012
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:004781
  
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  RRIDCUR:Validated RRID:IMSR_JAX:004781
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sciencedirect.com/science/article/pii/S2211124721003260
Feb 2021
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Osteoclasts recycle via osteomorphs during RANKL-stimulated bone resorption

1
1. scibot 26 Feb 2021
  
  in Public
  
  JAX:004781
  
  DOI: 10.1016/j.cell.2021.02.002
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
  Curator: @Naa003
  
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sciencedirect.com/science/article/pii/S0092867421001525
Jan 2021
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Nod1 promotes colorectal carcinogenesis by regulating the immunosuppressive functions of tumor-infiltrating myeloid cells

1
1. scibot 28 Jan 2021
  
  in Public
  
  Cat# 004781
  
  DOI: 10.1016/j.celrep.2020.108677
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:004781
  
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  RRIDCUR:Missing RRID:IMSR_JAX:004781
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sciencedirect.com/science/article/pii/S2211124720316661
Dec 2020
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Hypusination Orchestrates the Antimicrobial Response of Macrophages

1
1. scibot 17 Dec 2020
  
  in Public
  
  C57BL/6J Lyz2cre/cre
  
  DOI: 10.1016/j.celrep.2020.108510
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:004781
  
  Curator comments: B6.129P2-Lyz2tm1(cre)Ifo/J Mus musculus IMSR Cat# JAX:004781
  
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  RRIDCUR:Missing RRID:IMSR_JAX:004781
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sciencedirect.com/science/article/pii/S2211124720314996
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Regulatory T Cells Support Breast Cancer Progression by Opposing IFN-γ-Dependent Functional Reprogramming of Myeloid Cells

1
1. scibot 15 Dec 2020
  
  in Public
  
  B6.129P2-Lyz2tm1(cre)Ifo/J
  
  DOI: 10.1016/j.celrep.2020.108482
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:004781
  
  Curator comments: B6.129P2-Lyz2tm1(cre)Ifo/J Mus musculus IMSR Cat# JAX:004781
  
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  RRIDCUR:Missing RRID:IMSR_JAX:004781
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sciencedirect.com/science/article/pii/S2211124720314716
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Nuclear cGAS Functions Non-canonically to Enhance Antiviral Immunity via Recruiting Methyltransferase Prmt5

1
1. scibot 12 Dec 2020
  
  in Public
  
  Lyz2-Cre: B6.129P2-Lyz2tm1(cre)Ifo/J b
  
  DOI: 10.1016/j.celrep.2020.108490
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:004781
  
  Curator comments: B6.129P2-Lyz2tm1(cre)Ifo/J Mus musculus IMSR Cat# JAX:004781
  
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  RRIDCUR:Missing RRID:IMSR_JAX:004781
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sciencedirect.com/science/article/pii/S2211124720314790
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Neutrophil infiltration regulates clock-gene expression to organize daily hepatic metabolism

1
1. scibot 12 Dec 2020
  
  in Public
  
  RRID:IMSR_JAX:004781
  
  DOI: 10.7554/eLife.59258
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
  Curator: @evieth
  
  SciCrunch record: RRID:IMSR_JAX:004781
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7723411/
Nov 2020
elifesciences.org elifesciences.org

MicroRNAs of the miR-17~9 family maintain adipose tissue macrophage homeostasis by sustaining IL-10 expression

1
1. scibot 26 Nov 2020
  
  in Public
  
  The Jackson LaboratoryStock No: 004781
  
  DOI: 10.7554/eLife.55676
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
  Curator: @evieth
  
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elifesciences.org/articles/55676
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Adverse effects of BMPR2 suppression in macrophages in animal models of pulmonary hypertension

1
1. scibot 18 Nov 2020
  
  in Public
  
  004781
  
  DOI: 10.1177/2045894019856483
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7074495/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Loss of Myeloid BMPR1a Alters Differentiation and Reduces Mouse Prostate Cancer Growth

1
1. scibot 18 Nov 2020
  
  in Public
  
  004781
  
  DOI: 10.3389/fonc.2020.00357
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7154049/
Sep 2020
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HILPDA Uncouples Lipid Droplet Accumulation in Adipose Tissue Macrophages from Inflammation and Metabolic Dysregulation

1
1. scibot 12 Sep 2020
  
  in Public
  
  RRID:IMSR_JAX:004781
  
  DOI: 10.1016/j.celrep.2020.01.046
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
  Curator: @ethanbadger
  
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  RRID:IMSR_JAX:004781 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S221112472030070X
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Bmal1 integrates mitochondrial metabolism and macrophage activation

1
1. scibot 11 Sep 2020
  
  in Public
  
  JAX:004781
  
  DOI: 10.7554/eLife.54090
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
  Curator: @evieth
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7259948/
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Type I Interferons Suppress Anti-parasitic Immunity and Can Be Targeted to Improve Treatment of Visceral Leishmaniasis

1
1. scibot 11 Sep 2020
  
  in Public
  
  RRID:IMSR_JAX:004781
  
  DOI: 10.1016/j.celrep.2020.01.099
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
  Curator: @ethanbadger
  
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sciencedirect.com/science/article/pii/S2211124720301339
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

BPS Publications

1
1. scibot 04 Sep 2020
  
  in Public
  
  LysM.Cre
  
  DOI: 10.1111/bph.14945
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:004781
  
  Curator comments: B6.129P2-Lyz2tm1(cre)Ifo/J Mus musculus IMSR Cat# JAX:004781
  
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  RRIDCUR:Missing RRID:IMSR_JAX:004781
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.14945
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Dopamine Uses the DRD5-ARRB2-PP2A Signaling Axis to Block the TRAF6-Mediated NF-κB Pathway and Suppress Systemic Inflammation

1
1. scibot 04 Sep 2020
  
  in Public
  
  Mouse:LysM-Cre
  
  DOI: 10.1016/j.molcel.2020.01.022
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
  Curator: @ethanbadger
  
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  RRID:IMSR_JAX:004781 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S1097276520300435
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A Neurotrophic Mechanism Directs Sensory Nerve Transit in Cranial Bone

1
1. scibot 03 Sep 2020
  
  in Public
  
  Jackson LaboratoryStock #004781
  
  DOI: 10.1016/j.celrep.2020.107696
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
  Curator: @ethanbadger
  
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sciencedirect.com/science/article/pii/S2211124720306495
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Targeting Lymph Node Niches Enhances Type 1 Immune Responses to Immunization

1
1. scibot 03 Sep 2020
  
  in Public
  
  The Jackson LaboratoryCat# 004781
  
  DOI: 10.1016/j.celrep.2020.107679
  
  Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)
  
  Curator: @ethanbadger
  
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  RRID:IMSR_JAX:004781
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sciencedirect.com/science/article/pii/S221112472030632X
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The Unfolded Protein Response Mediator PERK Governs Myeloid Cell-Driven Immunosuppression in Tumors through Inhibition of STING Signaling

1
1. scibot 03 Sep 2020
  
  in Public
  
  Jackson LaboratoryCat# 004781
  
  DOI: 10.1016/j.immuni.2020.03.004
  
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Macrophages Expressing GALC Improve Peripheral Krabbe Disease by a Mechanism Independent of Cross-Correction

1
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  The Jackson LaboratoryCat#004781
  
  DOI: 10.1016/j.neuron.2020.03.031
  
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TMEM173 Drives Lethal Coagulation in Sepsis

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  The Jackson Laboratory004781
  
  DOI: 10.1016/j.chom.2020.02.004
  
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Tuft-Cell-Derived Leukotrienes Drive Rapid Anti-helminth Immunity in the Small Intestine but Are Dispensable for Anti-protist Immunity

1
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  Jackson LaboratoryCat# 004781
  
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Macrophage K63-Linked Ubiquitination of YAP Promotes Its Nuclear Localization and Exacerbates Atherosclerosis

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  LysMcre
  
  DOI: 10.1016/j.celrep.2020.107990
  
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Neutrophil Caspase-11 Is Essential to Defend against a Cytosol-Invasive Bacterium

1
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  LysM-cre: B6.129P2-Lyz2tm1(cre)Ifo/J
  
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Neural regulation of energy and bone homeostasis by the synaptic adhesion molecule Calsyntenin-3

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  DOI: 10.1038/s12276-020-0419-8
  
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CD137 Signaling Regulates Acute Colitis via RALDH2-Expressing CD11b−CD103+ DCs

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  DOI: 10.1016/j.celrep.2020.02.103
  
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The Cytokine TNF Promotes Transcription Factor SREBP Activity and Binding to Inflammatory Genes to Activate Macrophages and Limit Tissue Repair

1
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  RRID:IMSR_JAX:004781
  
  DOI: 10.1016/j.immuni.2019.06.005
  
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Liver-Derived Signals Sequentially Reprogram Myeloid Enhancers to Initiate and Maintain Kupffer Cell Identity

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  RRID:IMSR_JAX:004781
  
  DOI: 10.1016/j.immuni.2019.09.002
  
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Rare Pulmonary Neuroendocrine Cells Are Stem Cells Regulated by Rb, p53, and Notch

1
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  RRID:IMSR_JAX:004781
  
  DOI: 10.1016/j.cell.2019.09.010
  
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Accelerated phosphatidylcholine turnover in macrophages promotes adipose tissue inflammation in obesity

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  DOI: 10.7554/eLife.47990
  
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Untitled document

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  RRID:IMSR_JAX:004781
  
  DOI: 10.1093/hmg/ddz009
  
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emboj.embopress.org emboj.embopress.org

BRD4 directs hematopoietic stem cell development and modulates macrophage inflammatory responses

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  RRID:IMSR_JAX:004781
  
  DOI: 10.15252/embj.2018100293
  
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Untitled document

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  DOI: 10.1016/j.celrep.2018.11.100
  
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Nov 2018
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Cholesterol Homeostatic Regulator SCAP-SREBP2 Integrates NLRP3 Inflammasome Activation and Cholesterol Biosynthetic Signaling in Macrophages

1
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Hypothalamic Macrophage Inducible Nitric Oxide Synthase Mediates Obesity-Associated Hypothalamic Inflammation

1
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  JAX:004781
  
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The Endotoxin Delivery Protein HMGB1 Mediates Caspase-11-Dependent Lethality in Sepsis

1
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SYK-CARD9 Signaling Axis Promotes Gut Fungi-Mediated Inflammasome Activation to Restrict Colitis and Colon Cancer

1
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  004781
  
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Non-canonical NF-κB Antagonizes STING Sensor-Mediated DNA Sensing in Radiotherapy

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Lipid Peroxidation Drives Gasdermin D-Mediated Pyroptosis in Lethal Polymicrobial Sepsis

1
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  004781
  
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Bacteroides fragilis Toxin Coordinates a Pro-carcinogenic Inflammatory Cascade via Targeting of Colonic Epithelial Cells

1
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Myeloid Cell-Derived Reactive Oxygen Species Induce Epithelial Mutagenesis

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Activation of p53 in Immature Myeloid Precursor Cells Controls Differentiation into Ly6c+CD103+ Monocytic Antigen-Presenting Cells in Tumors

1
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  JAX:004781
  
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Staphylococcus aureus Epicutaneous Exposure Drives Skin Inflammation via IL-36-Mediated T Cell Responses

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The Cytokine TGF-β Promotes the Development and Homeostasis of Alveolar Macrophages

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Dichotomous Expression of TNF Superfamily Ligands on Antigen-Presenting Cells Controls Post-priming Anti-viral CD4+ T Cell Immunity

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Metabolic Adaptation Establishes Disease Tolerance to Sepsis

1
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  Curator: @bandrow
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5480394/
Nov 2017
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The DNA Methylcytosine Dioxygenase Tet2 Sustains Immunosuppressive Function of Tumor-Infiltrating Myeloid Cells to Promote Melanoma Progression

1
1. scibot 08 Nov 2017
  
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Dendritic Cells but Not Macrophages Sense Tumor Mitochondrial DNA for Cross-priming through Signal Regulatory Protein α Signaling

1
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Cholesterol Accumulation in Dendritic Cells Links the Inflammasome to Acquired Immunity

1
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elifesciences.org elifesciences.org

Macrophage dysfunction initiates colitis during weaning of infant mice lacking the interleukin-10 receptor

1
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  RRID:IMSR_JAX:004781
  
  Curator: @chewbeccax
  
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elifesciences.org/articles/27652
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Metabolic Adaptation Establishes Disease Tolerance to Sepsis

1
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  JAX stock 004781
  
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  RRID:IMSR_JAX:004781 RRIDCUR:Missing
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scibot

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sciencedirect.com/science/article/pii/S0092867417305925
www.jneurosci.org www.jneurosci.org

MicroRNA Profiling Reveals Marker of Motor Neuron Disease in ALS Models

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1. scibot 08 Nov 2017
  
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  IMSR_JAX:004781
  
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  SciCrunch record: RRID:IMSR_JAX:004781
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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  RRID:IMSR_JAX:004781
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scibot

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jneurosci.org/content/37/22/5574

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