147 Matching Annotations
  1. Last 7 days
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Membrane-bound O-acyltransferase 7 (MBOAT7) shapes lysosomal lipid homeostasis and function to control alcohol-associated liver injury
    1
    1. scibot 24 Apr 2024
      RRID:IMSR_JAX:004781

      DOI: 10.7554/eLife.92243

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    ncbi.nlm.nih.gov/pmc/articles/PMC11034944/
  3. Apr 2024
  4. www.sciencedirect.com www.sciencedirect.com
    Endothelial cell expression of a STING gain-of-function mutation initiates pulmonary lymphocytic infiltration
    1
    1. scibot 19 Apr 2024
      Cat#004781

      DOI: 10.1016/j.celrep.2024.114114

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    sciencedirect.com/science/article/pii/S221112472400442X
  5. www.sciencedirect.com www.sciencedirect.com
    Squalene-epoxidase-catalyzed 24(S),25-epoxycholesterol synthesis promotes trained-immunity-mediated antitumor activity
    2
    1. scibot 18 Apr 2024
      RRID:IMSR_JAX:004781

      DOI: 10.1016/j.celrep.2024.114094

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    2. scibot 18 Apr 2024
      RRID:IMSR_JAX:004781

      DOI: 10.1016/j.celrep.2024.114094

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    sciencedirect.com/science/article/pii/S2211124724004224
  6. www.sciencedirect.com www.sciencedirect.com
    LXR/CD38 activation drives cholesterol-induced macrophage senescence and neurodegeneration via NAD+ depletion
    1
    1. scibot 18 Apr 2024
      JAX:004781

      DOI: 10.1016/j.celrep.2024.114102

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    sciencedirect.com/science/article/pii/S2211124724004303
  7. www.sciencedirect.com www.sciencedirect.com
    Jagged2 targeting in lung cancer activates anti-tumor immunity via Notch-induced functional reprogramming of tumor-associated macrophages
    1
    1. scibot 18 Apr 2024
      RRID:IMSR_JAX:004781

      DOI: 10.1016/j.immuni.2024.03.020

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    sciencedirect.com/science/article/pii/S1074761324001419
  8. alz-journals.onlinelibrary.wiley.com alz-journals.onlinelibrary.wiley.com
    Peripheral HMGB1 is linked to O3 pathology of disease-associated astrocytes and amyloid
    1
    1. scibot 17 Apr 2024
      RRID:IMSR_JAX:004781

      DOI: 10.1002/alz.13825

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    alz-journals.onlinelibrary.wiley.com/doi/10.1002/alz.13825
  9. Mar 2024
  10. www.sciencedirect.com www.sciencedirect.com
    A stress sensor, IRE1α, is required for bacterial-exotoxin-induced interleukin-1β production in tissue-resident macrophages
    2
    1. scibot 29 Mar 2024
      JAX:004781

      DOI: 10.1016/j.celrep.2024.113981

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    2. scibot 29 Mar 2024
      JAX:004781

      DOI: 10.1016/j.celrep.2024.113981

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    sciencedirect.com/science/article/pii/S2211124724003097
  11. www.sciencedirect.com www.sciencedirect.com
    MAFB in macrophages regulates cold-induced neuronal density in brown adipose tissue
    1
    1. scibot 27 Mar 2024
      RRID:IMSR_JAX:004781

      DOI: 10.1016/j.celrep.2024.113978

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    sciencedirect.com/science/article/pii/S2211124724003061
  12. www.sciencedirect.com www.sciencedirect.com
    Clinical drug screening reveals clofazimine potentiates the efficacy while reducing the toxicity of anti-PD-1 and CTLA-4 immunotherapy
    1
    1. scibot 22 Mar 2024
      The Jackson LaboratoryCat#004781

      DOI: 10.1016/j.ccell.2024.03.001

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    sciencedirect.com/science/article/pii/S1535610824000801
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RBP-J regulates homeostasis and function of circulating Ly6Clo monocytes
    1
    1. scibot 19 Mar 2024
      Strain #: 004781 from Jackson Laboratory

      DOI: 10.7554/eLife.88135

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      Curator: @evieth

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    ncbi.nlm.nih.gov/pmc/articles/PMC10942619/
  14. www.sciencedirect.com www.sciencedirect.com
    Neutrophil-inflicted vasculature damage suppresses immune-mediated optic nerve regeneration
    1
    1. scibot 19 Mar 2024
      The Jackson LaboratoryStock# 004781

      DOI: 10.1016/j.celrep.2024.113931

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    sciencedirect.com/science/article/pii/S2211124724002596
  15. www.sciencedirect.com www.sciencedirect.com
    PAD4 controls tumor immunity via restraining the MHC class II machinery in macrophages
    2
    1. scibot 15 Mar 2024
      JAX:004781

      DOI: 10.1016/j.celrep.2024.113942

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    2. scibot 15 Mar 2024
      JAX:004781

      DOI: 10.1016/j.celrep.2024.113942

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    sciencedirect.com/science/article/pii/S2211124724002705
  16. Feb 2024
  17. www.sciencedirect.com www.sciencedirect.com
    Downregulation of IRF8 in alveolar macrophages by G-CSF promotes metastatic tumor progression
    1
    1. scibot 29 Feb 2024
      The Jackson LaboratoryCat#004781

      DOI: 10.1016/j.isci.2024.109187

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    sciencedirect.com/science/article/pii/S2589004224004085
  18. www.sciencedirect.com www.sciencedirect.com
    IgG is an aging factor that drives adipose tissue fibrosis and metabolic decline
    1
    1. scibot 21 Feb 2024
      RRID:IMSR_JAX:004781

      DOI: 10.1016/j.cmet.2024.01.015

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    sciencedirect.com/science/article/abs/pii/S1550413124000159
  19. www.sciencedirect.com www.sciencedirect.com
    Amphiregulin from regulatory T cells promotes liver fibrosis and insulin resistance in non-alcoholic steatohepatitis
    2
    1. scibot 06 Feb 2024
      JAX:004781

      DOI: 10.1016/j.immuni.2024.01.009

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    2. scibot 06 Feb 2024
      JAX:004781

      DOI: 10.1016/j.immuni.2024.01.009

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    sciencedirect.com/science/article/pii/S1074761324000347
  20. Jan 2024
  21. www.sciencedirect.com www.sciencedirect.com
    Type 2 cytokine signaling in macrophages protects from cellular senescence and organismal aging
    1
    1. scibot 23 Jan 2024
      The Jackson LaboratoryStrain #004781

      DOI: 10.1016/j.immuni.2024.01.001

      Resource: (IMSR Cat# JAX_004781,RRID:IMSR_JAX:004781)

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    sciencedirect.com/science/article/pii/S1074761324000268
  22. www.nature.com www.nature.com
    Myeloid cell-associated aromatic amino acid metabolism facilitates CNS myelin regeneration
    1
    1. scibot 05 Jan 2024
      RRID:IMSR_JAX:004781

      DOI: 10.1038/s41536-023-00345-9

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    nature.com/articles/s41536-023-00345-9
  23. www.sciencedirect.com www.sciencedirect.com
    Cooperative sensing of mitochondrial DNA by ZBP1 and cGAS promotes cardiotoxicity
    1
    1. scibot 04 Jan 2024
      004781

      DOI: 10.1016/j.cell.2023.05.039

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      Curator: @bandrow

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    sciencedirect.com/science/article/pii/S0092867423005913
  24. www.nature.com www.nature.com
    Age-associated features of norovirus infection analysed in mice
    1
    1. scibot 03 Jan 2024
      004781

      DOI: 10.1038/s41564-023-01383-1

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    nature.com/articles/s41564-023-01383-1
  25. rupress.org rupress.org
    Trained immunity of alveolar macrophages enhances injury resolution via KLF4-MERTK-mediated efferocytosis
    1
    1. scibot 02 Jan 2024
      004781

      DOI: 10.1084/jem.20221388

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    rupress.org/jem/article/220/11/e20221388/276204/Trained-immunity-of-alveolar-macrophages-enhances
  26. portlandpress.com portlandpress.com
    Myeloid cell-specific deletion of epidermal growth factor receptor aggravates acute cardiac injury
    1
    1. scibot 02 Jan 2024
      004781

      DOI: 10.1042/CS20230804

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    portlandpress.com/clinsci/article/137/19/1513/233529/Myeloid-cell-specific-deletion-of-epidermal-growth
  27. Dec 2023
  28. www.sciencedirect.com www.sciencedirect.com
    Myeloid cell-derived creatine in the hypoxic niche promotes glioblastoma growth
    1
    1. scibot 22 Dec 2023
      JAX:004781

      DOI: 10.1016/j.cmet.2023.11.013

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    sciencedirect.com/science/article/pii/S155041312300445X
  29. www.sciencedirect.com www.sciencedirect.com
    Reprogramming of tumor-associated macrophages via NEDD4-mediated CSF1R degradation by targeting USP18
    1
    1. scibot 17 Dec 2023
      RRID:IMSR_JAX:004781

      DOI: 10.1016/j.celrep.2023.113560

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    sciencedirect.com/science/article/pii/S2211124723015723
  30. www.sciencedirect.com www.sciencedirect.com
    Early cellular mechanisms of type I interferon-driven susceptibility to tuberculosis
    1
    1. scibot 02 Dec 2023
      RRID:IMSR_JAX:004781

      DOI: 10.1016/j.cell.2023.11.002

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    sciencedirect.com/science/article/pii/S0092867423012175
  31. Oct 2023
  32. www.biorxiv.org www.biorxiv.org
    The RNA binding protein, HNRNPA2B1, regulates IFNG signaling in macrophages
    1
    1. scibot 24 Oct 2023
      RRID:IMSR_JAX:004781

      DOI: 10.1101/2023.10.12.562050

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    biorxiv.org/content/10.1101/2023.10.12.562050v1
  33. www.sciencedirect.com www.sciencedirect.com
    Neutrophils resist ferroptosis and promote breast cancer metastasis through aconitate decarboxylase 1
    1
    1. scibot 13 Oct 2023
      RRID:IMSR_JAX:004781

      DOI: 10.1016/j.cmet.2023.09.004

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    sciencedirect.com/science/article/pii/S1550413123003364
  34. Sep 2023
  35. www.sciencedirect.com www.sciencedirect.com
    Myeloid BAF60a deficiency alters metabolic homeostasis and exacerbates atherosclerosis
    1
    1. scibot 30 Sep 2023
      JAX:004781

      DOI: 10.1016/j.celrep.2023.113171

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    sciencedirect.com/science/article/pii/S221112472301183X
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Adenosine A2A receptor is a tumor suppressor of NASH-associated hepatocellular carcinoma
    1
    1. scibot 28 Sep 2023
      RRID:IMSR_JAX:004781

      DOI: 10.1016/j.xcrm.2023.101188

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    ncbi.nlm.nih.gov/pmc/articles/PMC10518627/
  37. Aug 2023
  38. 52.53.155.43 52.53.155.43
    The miR-23-27-24 clusters drive lipid-associated macrophage proliferation in obese adipose tissue
    2
    1. scibot 12 Aug 2023
      JAX:004781

      DOI: 10.1016/j.celrep.2023.112928

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    2. scibot 05 Aug 2023
      JAX:004781

      DOI: 10.1016/j.celrep.2023.112928

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    52.53.155.43/4a6b7aa5507bdf2becad8c264c3514e078fa27b5/PIIS2211124723009397-html.html
  39. Jul 2023
  40. www.sciencedirect.com www.sciencedirect.com
    LYVE-1+ macrophages form a collaborative CCR5-dependent perivascular niche that influences chemotherapy responses in murine breast cancer
    1
    1. scibot 13 Jul 2023
      RRID:IMSR_JAX:004781

      DOI: 10.1016/j.devcel.2023.06.006

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    sciencedirect.com/science/article/pii/S1534580723003040
  41. Jun 2023
  42. www.biorxiv.org www.biorxiv.org
    Autophagy is required to prevent early pro-inflammatory responses and neutrophil recruitment during Mycobacterium tuberculosis infection without affecting pathogen replication in macrophages
    1
    1. scibot 08 Jun 2023
      Jax #004781

      DOI: 10.1101/2022.11.04.515221

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    biorxiv.org/content/10.1101/2022.11.04.515221v2
  43. May 2023
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Macrophages regulate gastrointestinal motility through complement component 1q
    1
    1. scibot 18 May 2023
      Stock #004781

      DOI: 10.7554/eLife.78558

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      Curator: @evieth

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    ncbi.nlm.nih.gov/pmc/articles/PMC10185340/
  45. Apr 2023
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neutrophil Conversion to a Tumor-Killing Phenotype Underpins Effective Microbial Therapy
    1
    1. scibot 21 Apr 2023
      RRID:IMSR_JAX:004781

      DOI: 10.1158/0008-5472.CAN-21-4025

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    ncbi.nlm.nih.gov/pmc/articles/PMC10102850/
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    cDC1 coordinate innate and adaptive responses in the omentum required for T cell priming and memory
    1
    1. scibot 05 Apr 2023
      RRID:IMSR_JAX:004781

      DOI: 10.1126/sciimmunol.abq7432

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    ncbi.nlm.nih.gov/pmc/articles/PMC9835709/
  48. Feb 2023
  49. www.science.org www.science.org
    CD47 halts Ptpn6-deficient neutrophils from provoking lethal inflammation
    1
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      004781

      DOI: 10.1126/sciadv.ade3942

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  50. www.sciencedirect.com www.sciencedirect.com
    Renal control of life-threatening malarial anemia
    2
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      RRID:IMSR_JAX:004781

      DOI: 10.1016/j.celrep.2023.112057

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      RRID:IMSR_JAX:004

      DOI: 10.1016/j.celrep.2023.112057

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    sciencedirect.com/science/article/pii/S2211124723000682
  51. Oct 2022
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cbl-b Restrains Priming of Pathogenic Th17 Cells via the Inhibition of IL-6 Production by Macrophages
    1
    1. scibot 04 Oct 2022
      RRID:IMSR_JAX:004781

      DOI: 10.1016/j.isci.2022.105151

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    ncbi.nlm.nih.gov/pmc/articles/PMC9523381/
  53. Sep 2022
  54. www.sciencedirect.com www.sciencedirect.com
    Combined genetic deletion of GDF15 and FGF21 has modest effects on body weight, hepatic steatosis and insulin resistance in high fat fed mice
    1
    1. scibot 16 Sep 2022
      RRID:IMSR_JAX:004781

      DOI: 10.1016/j.molmet.2022.101589

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  55. www.sciencedirect.com www.sciencedirect.com
    Tumor-associated macrophages are shaped by intratumoral high potassium via Kir2.1
    1
    1. scibot 15 Sep 2022
      JAX:004781

      DOI: 10.1016/j.cmet.2022.08.016

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  56. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Deficiency of Ninjurin1 attenuates LPS/D-galactosamine-induced acute liver failure by reducing TNF-α-induced apoptosis in hepatocytes
    1
    1. scibot 14 Sep 2022
      RRID:IMSR_JAX:004781

      DOI: 10.1111/jcmm.17538

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    onlinelibrary.wiley.com/doi/full/10.1111/jcmm.17538
  57. Aug 2022
  58. www.sciencedirect.com www.sciencedirect.com
    Adenosine metabolized from extracellular ATP promotes type 2 immunity through triggering A2BAR signaling in intestinal epithelial cells
    1
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      Jax Strain #004781

      DOI: 10.1016/j.celrep.2022.111150

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    sciencedirect.com/science/article/pii/S2211124722009597
  59. Jun 2022
  60. www.sciencedirect.com www.sciencedirect.com
    The STING1-MYD88 complex drives ACOD1/IRG1 expression and function in lethal innate immunity
    1
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      The Jackson Laboratory004781

      DOI: 10.1016/j.isci.2022.104561

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    sciencedirect.com/science/article/pii/S2589004222008331
  61. www.sciencedirect.com www.sciencedirect.com
    Tet2 deficiency drives liver microbiome dysbiosis triggering Tc1 cell autoimmune hepatitis
    1
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      Jackson LaboratoryStock No: 004781

      DOI: 10.1016/j.chom.2022.05.006

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    sciencedirect.com/science/article/pii/S1931312822002669
  62. May 2022
  63. www.sciencedirect.com www.sciencedirect.com
    Activation of the transcription factor NRF2 mediates the anti-inflammatory properties of a subset of over-the-counter and prescription NSAIDs
    1
    1. scibot 19 May 2022
      JAX:004781

      DOI: 10.1016/j.immuni.2022.04.015

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    sciencedirect.com/science/article/pii/S1074761322001868
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Macrophage-derived cholesterol contributes to therapeutic resistance in prostate cancer
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      JAX 004781

      DOI: 10.1158/0008-5472.CAN-20-4028

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    ncbi.nlm.nih.gov/pmc/articles/PMC8563406/
  65. Apr 2022
  66. www.sciencedirect.com www.sciencedirect.com
    TNF-α sculpts a maturation process in vivo by pruning tolerogenic dendritic cells
    1
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      Jackson LaboratoryStock# 004781

      DOI: 10.1016/j.celrep.2022.110657

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  67. www.sciencedirect.com www.sciencedirect.com
    Microbiota-dependent activation of the myeloid calcineurin-NFAT pathway inhibits B7H3- and B7H4-dependent anti-tumor immunity in colorectal cancer
    1
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      RRID:IMSR_JAX:004781

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  68. Mar 2022
  69. www.sciencedirect.com www.sciencedirect.com
    Notch-mediated lactate metabolism regulates MDSC development through the Hes1/MCT2/c-Jun axis
    1
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      JAX:004781

      DOI: 10.1016/j.celrep.2022.110451

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    sciencedirect.com/science/article/pii/S2211124722001784
  70. Feb 2022
  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tryptophan-derived microbial metabolites activate the aryl hydrocarbon receptor in tumor-associated macrophages to suppress anti-tumor immunity
    2
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      Jax: 004781

      DOI: 10.1016/j.immuni.2022.01.006

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      Jax: 004781

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    ncbi.nlm.nih.gov/pmc/articles/PMC8888129/
  72. Dec 2021
  73. www.sciencedirect.com www.sciencedirect.com
    Macrophages transfer mitochondria to sensory neurons to resolve inflammatory pain
    1
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      RRID:IMSR_JAX:004781

      DOI: 10.1016/j.neuron.2021.11.020

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    sciencedirect.com/science/article/pii/S0896627321009697
  74. www.sciencedirect.com www.sciencedirect.com
    Inflammatory macrophages exploit unconventional pro-phagocytic integrins for phagocytosis and anti-tumor immunity
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      Stock No: 004781

      DOI: 10.1016/j.celrep.2021.110111

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    sciencedirect.com/science/article/pii/S2211124721016053
  75. Nov 2021
  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Susceptibility rhythm to bacterial endotoxin in myeloid clock-knockout mice
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      RRID:IMSR_JAX:004781

      DOI: 10.7554/eLife.62469

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    ncbi.nlm.nih.gov/pmc/articles/PMC8598165/
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    COMMD10 is critical for Kupffer cell survival and controls Ly6Chi monocyte differentiation and inflammation in the injured liver
    1
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      Stock No: 004781

      DOI: 10.1016/j.celrep.2021.110026

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    sciencedirect.com/science/article/pii/S2211124721015084
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    m6A mRNA methylation-directed myeloid cell activation controls progression of NAFLD and obesity
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      Stock# 004781

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    sciencedirect.com/science/article/pii/S2211124721014479
  79. Oct 2021
  80. www.sciencedirect.com www.sciencedirect.com
    Enteric pathogens induce tissue tolerance and prevent neuronal loss from subsequent infections
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      004781

      DOI: 10.1016/j.cell.2021.10.004

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    sciencedirect.com/science/article/pii/S0092867421011788
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    Myeloid lineage contributes to pathological choroidal neovascularization formation via SOCS3
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      004781

      DOI: 10.1016/j.ebiom.2021.103632

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    sciencedirect.com/science/article/pii/S2352396421004254
  82. Sep 2021
  83. www.sciencedirect.com www.sciencedirect.com
    Tumor-derived exosomes drive immunosuppressive macrophages in a pre-metastatic niche through glycolytic dominant metabolic reprogramming
    1
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      Stock#004781

      DOI: 10.1016/j.cmet.2021.09.002

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    sciencedirect.com/science/article/pii/S1550413121004216
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    Senescent immune cells release grancalcin to promote skeletal aging
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      004781

      DOI: 10.1016/j.cmet.2021.08.009

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    sciencedirect.com/science/article/pii/S1550413121003727
  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Loss of Mir146b with aging contributes to inflammation and mitochondrial dysfunction in thioglycollate-elicited peritoneal macrophages
    1
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      RRID:IMSR_JAX:004781

      DOI: 10.7554/eLife.66703

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    ncbi.nlm.nih.gov/pmc/articles/PMC8412946/
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    Deoxyhypusine synthase promotes a pro-inflammatory macrophage phenotype
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      004781

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    sciencedirect.com/science/article/pii/S1550413121003661
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    Sepsis expands a CD39+ plasmablast population that promotes immunosuppression via adenosine-mediated inhibition of macrophage antimicrobial activity
    1
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      Cat#004781

      DOI: 10.1016/j.immuni.2021.08.005

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    sciencedirect.com/science/article/pii/S1074761321003356
  88. Jul 2021
  89. www.sciencedirect.com www.sciencedirect.com
    Epithelial HMGB1 Delays Skin Wound Healing and Drives Tumor Initiation by Priming Neutrophils for NET Formation
    1
    1. scibot 31 Jul 2021
      Mouse: LysM Cre: B6.129P2-Lyz2tm1(cre)/lfo/J

      DOI: 10.1016/j.celrep.2019.10.104

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    sciencedirect.com/science/article/pii/S2211124719314378
  90. emboj.embopress.org emboj.embopress.org
    BRD4 directs hematopoietic stem cell development and modulates macrophage inflammatory responses
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      RRID:IMSR_JAX:004781

      DOI: 10.15252/embj.2018100293

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    emboj.embopress.org/content/early/2019/03/06/embj.2018100293
  91. academic.oup.com academic.oup.com
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      RRID:IMSR_JAX:004781

      DOI: 10.1093/hmg/ddz009

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    academic.oup.com/hmg/advance-article/doi/10.1093/hmg/ddz009/5280925
  92. www.sciencedirect.com www.sciencedirect.com
    Adrenergic Signaling in Muscularis Macrophages Limits Infection-Induced Neuronal Loss
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      Jackson Laboratory#004781

      DOI: 10.1016/j.cell.2019.12.002

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  93. onlinelibrary.wiley.com onlinelibrary.wiley.com
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  94. www.sciencedirect.com www.sciencedirect.com
    Tissue-Specific Macrophage Responses to Remote Injury Impact the Outcome of Subsequent Local Immune Challenge
    2
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      JAX: 004781

      DOI: 10.1016/j.immuni.2019.10.010

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      JAX:004781

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  95. journals.sagepub.com journals.sagepub.com
    Adverse effects of BMPR2 suppression in macrophages in animal models of pulmonary hypertension
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      004781

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  96. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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      RRID:IMSR_JAX:004781

      DOI: 10.7554/eLife.32497

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      RRID:IMSR_JAX:004781

      DOI: 10.7554/eLife.32497

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    ncbi.nlm.nih.gov/pmc/articles/PMC5762159/
  97. www.sciencedirect.com www.sciencedirect.com
    Lymph Node Mesenchymal and Endothelial Stromal Cells Cooperate via the RANK-RANKL Cytokine Axis to Shape the Sinusoidal Macrophage Niche
    1
    1. scibot 28 Jul 2021
      Mouse: B6.129P2-Lyz2tm1(cre)Ifo/J

      DOI: 10.1016/j.immuni.2019.05.008

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    sciencedirect.com/science/article/pii/S1074761319302286
  98. www.sciencedirect.com www.sciencedirect.com
    DNA methyltransferase 1 and Krüppel-like factor 4 axis regulates macrophage inflammation and atherosclerosis
    1
    1. scibot 28 Jul 2021
      004781

      DOI: 10.1016/j.yjmcc.2019.01.009

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    sciencedirect.com/science/article/pii/S0022282818308770
  99. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Club cells form lung adenocarcinomas and maintain the alveoli of adult mice
    1
    1. scibot 28 Jul 2021
      RRID:IMSR_JAX:004781

      DOI: 10.7554/eLife.45571

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    ncbi.nlm.nih.gov/pmc/articles/PMC6606035/
  100. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Diabetes reversal by inhibition of the low molecular weight tyrosine phosphatase
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    1. scibot 27 Jul 2021
      004781

      DOI: 10.1038/nchembio.2344

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    ncbi.nlm.nih.gov/pmc/articles/PMC5435566/
  101. Jun 2021
  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Resistance to lethal ectromelia virus infection requires Type I interferon receptor in natural killer cells and monocytes but not in adaptive immune or parenchymal cells
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      JAX:004781

      DOI: 10.1371/journal.ppat.1009593

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    ncbi.nlm.nih.gov/pmc/articles/PMC8172060/
  103. www.sciencedirect.com www.sciencedirect.com
    MYC-mediated early glycolysis negatively regulates proinflammatory responses by controlling IRF4 in inflammatory macrophages
    1
    1. scibot 16 Jun 2021
      RRID:IMSR_JAX:004781

      DOI: 10.1016/j.celrep.2021.109264

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    sciencedirect.com/science/article/pii/S2211124721006318
  104. www.sciencedirect.com www.sciencedirect.com
    Cytomegalovirus subverts macrophage identity
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    1. scibot 11 Jun 2021
      RRID:IMSR_JAX:004781

      DOI: 10.1016/j.cell.2021.05.009

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    sciencedirect.com/science/article/pii/S0092867421006267
  105. May 2021
  106. www.sciencedirect.com www.sciencedirect.com
    Western diet induces Paneth cell defects through microbiome alterations and farnesoid X receptor and type I interferon activation
    1
    1. scibot 19 May 2021
      Cat. # 004781

      DOI: 10.1016/j.chom.2021.04.004

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    sciencedirect.com/science/article/pii/S1931312821001803
  107. www.nature.com www.nature.com
    Feeding-induced resistance to acute lethal sepsis is dependent on hepatic BMAL1 and FXR signalling
    1
    1. scibot 15 May 2021
      RRID:IMSR_JAX:004781

      DOI: 10.1038/s41467-021-22961-z

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    nature.com/articles/s41467-021-22961-z
  108. www.sciencedirect.com www.sciencedirect.com
    Histone Deacetylase 3 Couples Mitochondria to Drive IL-1β-Dependent Inflammation by Configuring Fatty Acid Oxidation
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    1. scibot 07 May 2021
      JAX:004781

      DOI: 10.1016/j.molcel.2020.08.015

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    sciencedirect.com/science/article/pii/S1097276520305785
  109. Apr 2021
  110. www.sciencedirect.com www.sciencedirect.com
    MiR-690, an exosomal-derived miRNA from M2-polarized macrophages, improves insulin sensitivity in obese mice
    1
    1. scibot 30 Apr 2021
      JAX:004781

      DOI: 10.1016/j.cmet.2020.12.019

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    sciencedirect.com/science/article/pii/S1550413120307178
  111. www.sciencedirect.com www.sciencedirect.com
    Enteric helminth coinfection enhances host susceptibility to neurotropic flaviviruses via a tuft cell-IL-4 receptor signaling axis
    1
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      Cat # 004781

      DOI: 10.1016/j.cell.2021.01.051

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  112. www.sciencedirect.com www.sciencedirect.com
    The Intestinal Microbiome Restricts Alphavirus Infection and Dissemination through a Bile Acid-Type I IFN Signaling Axis
    1
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      RRID:IMSR_JAX:004781

      DOI: 10.1016/j.cell.2020.06.029

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    sciencedirect.com/science/article/pii/S0092867420308060
  113. www.sciencedirect.com www.sciencedirect.com
    Microbiota regulate innate immune signaling and protective immunity against cancer
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      JAX:004781

      DOI: 10.1016/j.chom.2021.03.016

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    sciencedirect.com/science/article/pii/S193131282100144X
  114. www.sciencedirect.com www.sciencedirect.com
    Hierarchical cell-type-specific functions of caspase-11 in LPS shock and antibacterial host defense
    1
    1. scibot 21 Apr 2021
      RRID:IMSR_JAX:004781

      DOI: 10.1016/j.celrep.2021.109012

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    sciencedirect.com/science/article/pii/S2211124721003260
  115. Feb 2021
  116. www.sciencedirect.com www.sciencedirect.com
    Osteoclasts recycle via osteomorphs during RANKL-stimulated bone resorption
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    1. scibot 26 Feb 2021
      JAX:004781

      DOI: 10.1016/j.cell.2021.02.002

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    sciencedirect.com/science/article/pii/S0092867421001525
  117. Jan 2021
  118. www.sciencedirect.com www.sciencedirect.com
    Nod1 promotes colorectal carcinogenesis by regulating the immunosuppressive functions of tumor-infiltrating myeloid cells
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    1. scibot 28 Jan 2021
      Cat# 004781

      DOI: 10.1016/j.celrep.2020.108677

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    sciencedirect.com/science/article/pii/S2211124720316661
  119. Dec 2020
  120. www.sciencedirect.com www.sciencedirect.com
    Hypusination Orchestrates the Antimicrobial Response of Macrophages
    1
    1. scibot 17 Dec 2020
      C57BL/6J Lyz2cre/cre

      DOI: 10.1016/j.celrep.2020.108510

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    sciencedirect.com/science/article/pii/S2211124720314996
  121. www.sciencedirect.com www.sciencedirect.com
    Regulatory T Cells Support Breast Cancer Progression by Opposing IFN-γ-Dependent Functional Reprogramming of Myeloid Cells
    1
    1. scibot 15 Dec 2020
      B6.129P2-Lyz2tm1(cre)Ifo/J

      DOI: 10.1016/j.celrep.2020.108482

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    sciencedirect.com/science/article/pii/S2211124720314716
  122. www.sciencedirect.com www.sciencedirect.com
    Nuclear cGAS Functions Non-canonically to Enhance Antiviral Immunity via Recruiting Methyltransferase Prmt5
    1
    1. scibot 12 Dec 2020
      Lyz2-Cre: B6.129P2-Lyz2tm1(cre)Ifo/J b

      DOI: 10.1016/j.celrep.2020.108490

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    sciencedirect.com/science/article/pii/S2211124720314790
  123. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neutrophil infiltration regulates clock-gene expression to organize daily hepatic metabolism
    1
    1. scibot 12 Dec 2020
      RRID:IMSR_JAX:004781

      DOI: 10.7554/eLife.59258

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    ncbi.nlm.nih.gov/pmc/articles/PMC7723411/
  124. Nov 2020
  125. elifesciences.org elifesciences.org
    MicroRNAs of the miR-17~9 family maintain adipose tissue macrophage homeostasis by sustaining IL-10 expression
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    1. scibot 26 Nov 2020
      The Jackson LaboratoryStock No: 004781

      DOI: 10.7554/eLife.55676

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    elifesciences.org/articles/55676
  126. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Adverse effects of BMPR2 suppression in macrophages in animal models of pulmonary hypertension
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    1. scibot 18 Nov 2020
      004781

      DOI: 10.1177/2045894019856483

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    ncbi.nlm.nih.gov/pmc/articles/PMC7074495/
  127. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Loss of Myeloid BMPR1a Alters Differentiation and Reduces Mouse Prostate Cancer Growth
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    1. scibot 18 Nov 2020
      004781

      DOI: 10.3389/fonc.2020.00357

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    ncbi.nlm.nih.gov/pmc/articles/PMC7154049/
  128. Sep 2020
  129. www.sciencedirect.com www.sciencedirect.com
    HILPDA Uncouples Lipid Droplet Accumulation in Adipose Tissue Macrophages from Inflammation and Metabolic Dysregulation
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    1. scibot 12 Sep 2020
      RRID:IMSR_JAX:004781

      DOI: 10.1016/j.celrep.2020.01.046

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    sciencedirect.com/science/article/pii/S221112472030070X
  130. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bmal1 integrates mitochondrial metabolism and macrophage activation
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    1. scibot 11 Sep 2020
      JAX:004781

      DOI: 10.7554/eLife.54090

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  131. www.sciencedirect.com www.sciencedirect.com
    Type I Interferons Suppress Anti-parasitic Immunity and Can Be Targeted to Improve Treatment of Visceral Leishmaniasis
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    1. scibot 11 Sep 2020
      RRID:IMSR_JAX:004781

      DOI: 10.1016/j.celrep.2020.01.099

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  132. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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    1. scibot 04 Sep 2020
      LysM.Cre

      DOI: 10.1111/bph.14945

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.14945
  133. www.sciencedirect.com www.sciencedirect.com
    Dopamine Uses the DRD5-ARRB2-PP2A Signaling Axis to Block the TRAF6-Mediated NF-κB Pathway and Suppress Systemic Inflammation
    1
    1. scibot 04 Sep 2020
      Mouse:LysM-Cre

      DOI: 10.1016/j.molcel.2020.01.022

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    sciencedirect.com/science/article/pii/S1097276520300435
  134. www.sciencedirect.com www.sciencedirect.com
    A Neurotrophic Mechanism Directs Sensory Nerve Transit in Cranial Bone
    1
    1. scibot 03 Sep 2020
      Jackson LaboratoryStock #004781

      DOI: 10.1016/j.celrep.2020.107696

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    sciencedirect.com/science/article/pii/S2211124720306495
  135. www.sciencedirect.com www.sciencedirect.com
    Targeting Lymph Node Niches Enhances Type 1 Immune Responses to Immunization
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      The Jackson LaboratoryCat# 004781

      DOI: 10.1016/j.celrep.2020.107679

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  136. www.sciencedirect.com www.sciencedirect.com
    The Unfolded Protein Response Mediator PERK Governs Myeloid Cell-Driven Immunosuppression in Tumors through Inhibition of STING Signaling
    1
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      Jackson LaboratoryCat# 004781

      DOI: 10.1016/j.immuni.2020.03.004

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    sciencedirect.com/science/article/pii/S1074761320301175
  137. www.sciencedirect.com www.sciencedirect.com
    Macrophages Expressing GALC Improve Peripheral Krabbe Disease by a Mechanism Independent of Cross-Correction
    1
    1. scibot 03 Sep 2020
      The Jackson LaboratoryCat#004781

      DOI: 10.1016/j.neuron.2020.03.031

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    sciencedirect.com/science/article/pii/S0896627320302385
  138. www.sciencedirect.com www.sciencedirect.com
    TMEM173 Drives Lethal Coagulation in Sepsis
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      The Jackson Laboratory004781

      DOI: 10.1016/j.chom.2020.02.004

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    sciencedirect.com/science/article/pii/S1931312820301128
  139. www.sciencedirect.com www.sciencedirect.com
    Tuft-Cell-Derived Leukotrienes Drive Rapid Anti-helminth Immunity in the Small Intestine but Are Dispensable for Anti-protist Immunity
    1
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      Jackson LaboratoryCat# 004781

      DOI: 10.1016/j.immuni.2020.02.005

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  140. www.sciencedirect.com www.sciencedirect.com
    Macrophage K63-Linked Ubiquitination of YAP Promotes Its Nuclear Localization and Exacerbates Atherosclerosis
    1
    1. scibot 03 Sep 2020
      LysMcre

      DOI: 10.1016/j.celrep.2020.107990

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  141. www.sciencedirect.com www.sciencedirect.com
    Neutrophil Caspase-11 Is Essential to Defend against a Cytosol-Invasive Bacterium
    1
    1. scibot 03 Sep 2020
      LysM-cre: B6.129P2-Lyz2tm1(cre)Ifo/J

      DOI: 10.1016/j.celrep.2020.107967

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  142. Aug 2020
  143. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neural regulation of energy and bone homeostasis by the synaptic adhesion molecule Calsyntenin-3
    1
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      004781

      DOI: 10.1038/s12276-020-0419-8

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  144. www.sciencedirect.com www.sciencedirect.com
    CD137 Signaling Regulates Acute Colitis via RALDH2-Expressing CD11b−CD103+ DCs
    1
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      JAX:4781

      DOI: 10.1016/j.celrep.2020.02.103

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  145. Jan 2020
  146. www.sciencedirect.com www.sciencedirect.com
    The Cytokine TNF Promotes Transcription Factor SREBP Activity and Binding to Inflammatory Genes to Activate Macrophages and Limit Tissue Repair
    1
    1. scibot 13 Jan 2020
      RRID:IMSR_JAX:004781

      DOI: 10.1016/j.immuni.2019.06.005

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  147. www.sciencedirect.com www.sciencedirect.com
    Liver-Derived Signals Sequentially Reprogram Myeloid Enhancers to Initiate and Maintain Kupffer Cell Identity
    1
    1. scibot 13 Jan 2020
      RRID:IMSR_JAX:004781

      DOI: 10.1016/j.immuni.2019.09.002

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  148. www.sciencedirect.com www.sciencedirect.com
    Rare Pulmonary Neuroendocrine Cells Are Stem Cells Regulated by Rb, p53, and Notch
    1
    1. scibot 13 Jan 2020
      RRID:IMSR_JAX:004781

      DOI: 10.1016/j.cell.2019.09.010

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  149. elifesciences.org elifesciences.org
    Accelerated phosphatidylcholine turnover in macrophages promotes adipose tissue inflammation in obesity
    1
    1. scibot 13 Jan 2020
      RRID:IMSR_JAX:004781

      DOI: 10.7554/eLife.47990

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  150. academic.oup.com academic.oup.com
    Untitled document
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    1. scibot 13 Jan 2020
      RRID:IMSR_JAX:004781

      DOI: 10.1093/hmg/ddz009

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    academic.oup.com/hmg/advance-article/doi/10.1093/hmg/ddz009/5280925
  151. emboj.embopress.org emboj.embopress.org
    BRD4 directs hematopoietic stem cell development and modulates macrophage inflammatory responses
    1
    1. scibot 13 Jan 2020
      RRID:IMSR_JAX:004781

      DOI: 10.15252/embj.2018100293

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    emboj.embopress.org/content/early/2019/03/06/embj.2018100293
  152. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 13 Jan 2020
      RRID:IMSR_JAX:004781

      DOI: 10.1016/j.celrep.2018.11.100

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      Curator: @evieth

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    sciencedirect.com/science/article/pii/S2211124718319065
  153. Nov 2018
  154. www.sciencedirect.com www.sciencedirect.com
    Cholesterol Homeostatic Regulator SCAP-SREBP2 Integrates NLRP3 Inflammasome Activation and Cholesterol Biosynthetic Signaling in Macrophages
    1
    1. scibot 05 Nov 2018
      JAX:004781

      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S1074761318303844
  155. www.sciencedirect.com www.sciencedirect.com
    Hypothalamic Macrophage Inducible Nitric Oxide Synthase Mediates Obesity-Associated Hypothalamic Inflammation
    1
    1. scibot 05 Nov 2018
      JAX:004781

      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S2211124718315304
  156. www.sciencedirect.com www.sciencedirect.com
    The Endotoxin Delivery Protein HMGB1 Mediates Caspase-11-Dependent Lethality in Sepsis
    1
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      004781

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    sciencedirect.com/science/article/pii/S1074761318303790
  157. www.sciencedirect.com www.sciencedirect.com
    SYK-CARD9 Signaling Axis Promotes Gut Fungi-Mediated Inflammasome Activation to Restrict Colitis and Colon Cancer
    1
    1. scibot 05 Nov 2018
      004781

      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S107476131830387X
  158. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Non-canonical NF-κB Antagonizes STING Sensor-Mediated DNA Sensing in Radiotherapy
    1
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      RRID:IMSR_JAX:004781

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    ncbi.nlm.nih.gov/pmc/articles/PMC6775781/
  159. www.sciencedirect.com www.sciencedirect.com
    Lipid Peroxidation Drives Gasdermin D-Mediated Pyroptosis in Lethal Polymicrobial Sepsis
    1
    1. scibot 05 Nov 2018
      004781

      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S1931312818302634
  160. www.sciencedirect.com www.sciencedirect.com
    Bacteroides fragilis Toxin Coordinates a Pro-carcinogenic Inflammatory Cascade via Targeting of Colonic Epithelial Cells
    1
    1. scibot 05 Nov 2018
      RRID:IMSR_JAX:004781

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    sciencedirect.com/science/article/pii/S1931312818300428
  161. www.sciencedirect.com www.sciencedirect.com
    Myeloid Cell-Derived Reactive Oxygen Species Induce Epithelial Mutagenesis
    1
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      JAX:004781

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    sciencedirect.com/science/article/pii/S153561081730507X
  162. www.sciencedirect.com www.sciencedirect.com
    Activation of p53 in Immature Myeloid Precursor Cells Controls Differentiation into Ly6c+CD103+ Monocytic Antigen-Presenting Cells in Tumors
    1
    1. scibot 05 Nov 2018
      JAX:004781

      Curator: @anp055

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    sciencedirect.com/science/article/pii/S1074761317305721
  163. www.sciencedirect.com www.sciencedirect.com
    Staphylococcus aureus Epicutaneous Exposure Drives Skin Inflammation via IL-36-Mediated T Cell Responses
    1
    1. scibot 05 Nov 2018
      RRID:IMSR_JAX:004781

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    sciencedirect.com/science/article/pii/S1931312817304419
  164. www.sciencedirect.com www.sciencedirect.com
    The Cytokine TGF-β Promotes the Development and Homeostasis of Alveolar Macrophages
    1
    1. scibot 05 Nov 2018
      RRID:IMSR_JAX:004781

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    sciencedirect.com/science/article/pii/S1074761317304612
  165. www.sciencedirect.com www.sciencedirect.com
    Dichotomous Expression of TNF Superfamily Ligands on Antigen-Presenting Cells Controls Post-priming Anti-viral CD4+ T Cell Immunity
    1
    1. scibot 05 Nov 2018
      RRID:IMSR_JAX:004781

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    sciencedirect.com/science/article/pii/S1074761317304697
  166. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Metabolic Adaptation Establishes Disease Tolerance to Sepsis
    1
    1. scibot 05 Nov 2018
      004781

      Curator: @bandrow

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    ncbi.nlm.nih.gov/pmc/articles/PMC5480394/
  167. Nov 2017
  168. www.sciencedirect.com www.sciencedirect.com
    The DNA Methylcytosine Dioxygenase Tet2 Sustains Immunosuppressive Function of Tumor-Infiltrating Myeloid Cells to Promote Melanoma Progression
    1
    1. scibot 08 Nov 2017
      RRID:IMSR_JAX:004781

      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S1074761317303278
  169. www.sciencedirect.com www.sciencedirect.com
    Dendritic Cells but Not Macrophages Sense Tumor Mitochondrial DNA for Cross-priming through Signal Regulatory Protein α Signaling
    1
    1. scibot 08 Nov 2017
      Jax:004781

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    sciencedirect.com/science/article/pii/S1074761317303230
  170. www.sciencedirect.com www.sciencedirect.com
    Cholesterol Accumulation in Dendritic Cells Links the Inflammasome to Acquired Immunity
    1
    1. scibot 08 Nov 2017
      JAX 004781

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    sciencedirect.com/science/article/pii/S1550413117302103
  171. elifesciences.org elifesciences.org
    Macrophage dysfunction initiates colitis during weaning of infant mice lacking the interleukin-10 receptor
    1
    1. scibot 08 Nov 2017
      RRID:IMSR_JAX:004781

      Curator: @chewbeccax

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    elifesciences.org/articles/27652
  172. www.sciencedirect.com www.sciencedirect.com
    Metabolic Adaptation Establishes Disease Tolerance to Sepsis
    1
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      JAX stock 004781

      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S0092867417305925
  173. www.jneurosci.org www.jneurosci.org
    MicroRNA Profiling Reveals Marker of Motor Neuron Disease in ALS Models
    1
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      IMSR_JAX:004781

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    jneurosci.org/content/37/22/5574
  174. www.jneurosci.org www.jneurosci.org
    Macrophage Transcriptional Profile Identifies Lipid Catabolic Pathways That Can Be Therapeutically Targeted after Spinal Cord Injury
    2
    1. scibot 08 Nov 2017
      IMSR_JAX:004781

      Curator: @chewbeccax

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    2. scibot 08 Nov 2017
      IMSR_JAX:004781

      Curator: @patriciaelyse_

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    jneurosci.org/content/37/9/2362
  175. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Macrophage PPARγ inhibits Gpr132 to mediate the anti-tumor effects of rosiglitazone
    1
    1. scibot 08 Nov 2017
      IMSR_JAX:004781

      Curator: @gabimpine

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    ncbi.nlm.nih.gov/pmc/articles/PMC5047746/
  176. elifesciences.org elifesciences.org
    Suppression of ischemia in arterial occlusive disease by JNK-promoted native collateral artery development
    1
    1. scibot 08 Nov 2017
      IMSR_JAX:004781

      Curator: @gabimpine

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    elifesciences.org/content/5/e18414