270 Matching Annotations
  1. Last 7 days
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    High-speed whole-genome sequencing of a Whippet: Rapid chromosome-level assembly and annotation of an extremely fast dog’s genome
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    1. scibot 26 Sep 2024
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      DOI: 10.46471/gigabyte.134

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    ncbi.nlm.nih.gov/pmc/articles/PMC11418881/
  3. Aug 2024
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR screening uncovers a long-range enhancer for ONECUT1 in pancreatic differentiation and links a diabetes risk variant
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    1. scibot 23 Aug 2024
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      DOI: 10.1016/j.celrep.2024.114640

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    Members of an array of zinc-finger proteins specify distinct Hox chromatin boundaries
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    1. scibot 23 Aug 2024
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    Transient Differentiation-State Plasticity Occurs During Acute Lymphoblastic Leukemia Initiation
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    1. scibot 22 Aug 2024
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      DOI: 10.1158/0008-5472.CAN-24-1090

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    Genomic dynamics of the Lower Yellow River Valley since the Early Neolithic
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    1. scibot 21 Aug 2024
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    sciencedirect.com/science/article/pii/S0960982224010029
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    SOX10 loss sensitizes melanoma cells to cytokine-mediated inflammatory cell death
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    1. scibot 18 Aug 2024
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      DOI: 10.1158/1541-7786.MCR-23-0290

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    ncbi.nlm.nih.gov/pmc/articles/PMC10842433/
  9. Jul 2024
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    Innate immune training restores pro-reparative myeloid functions to promote remyelination in the aged central nervous system
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    sciencedirect.com/science/article/pii/S1074761324003480
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    The primitive endoderm supports lineage plasticity to enable regulative development
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    1. scibot 24 Jul 2024
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    Stochastic RNA editing of the Complexin C-terminus within single neurons regulates neurotransmitter release
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      DOI: 10.1016/j.celrep.2023.113152

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  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Loss of ADAM29 does not affect viability and fertility in mice but improves wound healing
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    1. scibot 06 Jul 2024
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      DOI: 10.1016/j.isci.2024.110135

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  14. Jun 2024
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    Impacts of in-vitro zebularine treatment on genome-wide DNA methylation and transcriptomic profiles in Salix purpurea L.
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    1. scibot 28 Jun 2024
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    onlinelibrary.wiley.com/doi/10.1111/ppl.14403
  16. May 2024
  17. www.sciencedirect.com www.sciencedirect.com
    Reciprocal conversion between annual and polycarpic perennial flowering behavior in the Brassicaceae
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    1. scibot 30 May 2024
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      DOI: 10.1016/j.cell.2024.04.047

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      DOI: 10.1016/j.cell.2024.04.047

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      DOI: 10.1016/j.cell.2024.04.047

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    sciencedirect.com/science/article/pii/S0092867424004732
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    Heterochromatic 3D genome organization is directed by HP1a- and H3K9-dependent and independent mechanisms
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    1. scibot 30 May 2024
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      DOI: 10.1016/j.molcel.2024.05.002

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  19. 52.53.155.43 52.53.155.43
    mcr-23-0295-html.html
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    T-bet deficiency and Hic1 induction override TGF-β-dependency in the formation of CD103+ intestine-resident memory CD8+ T cells
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      DOI: 10.1016/j.celrep.2024.114258

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    The CD8+ T cell tolerance checkpoint triggers a distinct differentiation state defined by protein translation defects
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      DOI: 10.1016/j.immuni.2024.04.026

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    Integrative molecular analyses of the MD Anderson prostate cancer patient-derived xenograft (MDA PCa PDX) series
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    1. scibot 17 May 2024
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      DOI: 10.1158/1078-0432.CCR-23-2438

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    aacrjournals.org/clincancerres/article/30/10/2272/745168/Integrative-Molecular-Analyses-of-the-MD-Anderson
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    Integrative molecular and spatial analysis reveals evolutionary dynamics and tumor-immune interplay of in situ and invasive acral melanoma
    1
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      DOI: 10.1016/j.ccell.2024.04.012

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    sciencedirect.com/science/article/pii/S1535610824001363
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    Osr2 functions as a biomechanical checkpoint to aggravate CD8+ T cell exhaustion in tumor
    2
    1. scibot 14 May 2024
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      DOI: 10.1016/j.cell.2024.04.023

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      DOI: 10.1016/j.cell.2024.04.023

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    sciencedirect.com/science/article/pii/S0092867424004483
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    Transcription factor dynamics, oscillation, and functions in human enteroendocrine cell differentiation
    1
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      DOI: 10.1016/j.stem.2024.04.015

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  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Swd2/Cps35 determines H3K4 tri-methylation via interactions with Set1 and Rad6
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    1. scibot 09 May 2024
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      DOI: 10.1186/s12915-024-01903-3

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  27. Apr 2024
  28. www.sciencedirect.com www.sciencedirect.com
    No evidence for ac4C within human mRNA upon data reassessment
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      DOI: 10.1016/j.molcel.2024.03.017

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    sciencedirect.com/science/article/pii/S1097276524002272
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    Telomere dysfunction alters intestinal stem cell dynamics to promote cancer
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      DOI: 10.1016/j.devcel.2024.03.020

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    STAT3 couples activated tyrosine kinase signaling to the oncogenic core transcriptional regulatory circuitry of anaplastic large cell lymphoma
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      DOI: 10.1016/j.xcrm.2024.101472

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    ncbi.nlm.nih.gov/pmc/articles/PMC10983107/
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    Ancient genome of the Chinese Emperor Wu of Northern Zhou
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      DOI: 10.1016/j.cub.2024.02.059

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    sciencedirect.com/science/article/pii/S0960982224002409
  32. Mar 2024
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sex and age affect depot expression of Ca2+ channels in rat white fat adipocytes
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      DOI: 10.1530/JME-23-0108

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    ncbi.nlm.nih.gov/pmc/articles/PMC10959010/
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    Epigenetic MLH1 silencing concurs with mismatch repair deficiency in sporadic, naturally occurring colorectal cancer in rhesus macaques
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      DOI: 10.1186/s12967-024-04869-6

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    ncbi.nlm.nih.gov/pmc/articles/PMC10953092/
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    From degraded to deciphered: ATAC-seq’s application potential in forensic diagnosis
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      DOI: 10.1007/s00414-024-03206-2

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    link.springer.com/article/10.1007/s00414-024-03206-2
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    A simple method for rapid cloning of complete herpesvirus genomes
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    sciencedirect.com/science/article/pii/S266723752400002X
  37. Feb 2024
  38. aacrjournals.org aacrjournals.org
    Early Cancer Detection in Li-Fraumeni Syndrome with Cell-Free DNA
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      DOI: 10.1158/2159-8290.CD-23-0456

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    aacrjournals.org/cancerdiscovery/article/14/1/104/732565/Early-Cancer-Detection-in-Li-Fraumeni-Syndrome
  39. 52.53.155.43 52.53.155.43
    can-23-1129-html.html
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      DOI: 10.1158/0008-5472.can-23-1129

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  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Parkinson’s Disease Risk Enhancers in Microglia
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      DOI: 10.1016/j.isci.2024.108921

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    ncbi.nlm.nih.gov/pmc/articles/PMC10845915/
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    Development of sexual dimorphism of skeletal muscles through the adrenal cortex, caused by androgen-induced global gene suppression
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      DOI: 10.1016/j.celrep.2024.113715

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    sciencedirect.com/science/article/pii/S2211124724000433
  42. Jan 2024
  43. www.sciencedirect.com www.sciencedirect.com
    Inherited blood cancer predisposition through altered transcription elongation
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      DOI: 10.1016/j.cell.2023.12.016

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    sciencedirect.com/science/article/pii/S009286742301348X
  44. aacrjournals.org aacrjournals.org
    Early Cancer Detection in Li-Fraumeni Syndrome with Cell-Free DNA
    1
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      DOI: 10.1158/2159-8290.CD-23-0456

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    aacrjournals.org/cancerdiscovery/article/14/1/104/732565/Early-Cancer-Detection-in-Li-Fraumeni-Syndrome
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    Leveraging tissue-specific enhancer-target gene regulatory networks identifies enhancer somatic mutations that functionally impact lung cancer
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      DOI: 10.1158/0008-5472.CAN-23-1129

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    ncbi.nlm.nih.gov/pmc/articles/PMC10758689/
  46. Dec 2023
  47. www.sciencedirect.com www.sciencedirect.com
    SARS-CoV-2 RNA stabilizes host mRNAs to elicit immunopathogenesis
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      DOI: 10.1016/j.molcel.2023.11.032

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    Pluripotency state transition of embryonic stem cells requires the turnover of histone chaperone FACT on chromatin
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    Single-cell transcriptomics of human traumatic brain injury reveals activation of endogenous retroviruses in oligodendroglia
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  52. Nov 2023
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    SERPINB3-MYC axis induces the basal-like/squamous subtype and enhances disease progression in pancreatic cancer
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    LINE-1 retrotransposons drive human neuronal transcriptome complexity and functional diversification
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    LINE-1 retrotransposons drive human neuronal transcriptome complexity and functional diversification
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  57. Oct 2023
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    Unedited allogeneic iNKT cells show extended persistence in MHC-mismatched canine recipients
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  60. Sep 2023
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    Myeloid leukemia vulnerabilities embedded in long noncoding RNA locus MYNRL15
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    Characterization of the male-specific region containing the candidate sex-determining gene in Amur catfish (Silurus asotus) using third-generation- and pool-sequencing data
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    Identifying mechanisms of resistance by circulating tumour DNA in EVOLVE, a Phase II Trial of Cediranib Plus Olaparib for Ovarian Cancer at time of PARP Inhibitor Progression
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    Distinct pathways of adaptive evolution in Cryptococcus neoformans reveal a mutation in adenylyl cyclase with trade-offs for pathogenicity
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    The SMC5/6 complex compacts and silences unintegrated HIV-1 DNA and is antagonized by Vpr
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    Identification of the novel FOXP3-dependent Treg cell transcription factor MEOX1 by high-dimensional analysis of human CD4+ T cells
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    Mammalian SWI/SNF chromatin remodeling complexes promote tyrosine kinase inhibitor resistance in EGFR-mutant lung cancer
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    Cooperative and competitive regulation of the astrocytic transcriptome by neurons and endothelial cells: Impact on astrocyte maturation
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    Inter- and intra-tumor heterogeneity of genetic and immune profiles in inherited renal cell carcinoma
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    New scaffolds for type II JAK2 inhibitors overcome the acquired G993A resistance mutation
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  79. May 2023
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    KMT2D Deficiency Promotes Myeloid Leukemias which Is Vulnerable to Ribosome Biogenesis Inhibition
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    Complex Patterns of Genomic Heterogeneity Identified in 42 Tumor Samples and ctDNA of a Pulmonary Atypical Carcinoid Patient
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    Proteasome Inhibitors Silence Oncogenes in Multiple Myeloma through Localized Histone Deacetylase 3 Stabilization and Chromatin Condensation
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    Capture RIC-seq reveals positional rules of PTBP1-associated RNA loops in splicing regulation
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    ViReMa: a virus recombination mapper of next-generation sequencing data characterizes diverse recombinant viral nucleic acids
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    Hippo pathway and Bonus control developmental cell fate decisions in the Drosophila eye
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  92. Feb 2023
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    Runx1 controls auditory sensory neuron diversity in mice
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  94. Jan 2023
  95. www.biorxiv.org www.biorxiv.org
    A chromosome-scale assembly for tetraploid sour cherry (Prunus cerasus L.) ‘Montmorency’ identifies three distinct ancestral Prunus genomes
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  96. Dec 2022
  97. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cultural and demic co-diffusion of Tubo Empire on Tibetan Plateau
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  98. aacrjournals.org aacrjournals.org
    BAF complex maintains glioma stem cells in pediatric H3K27M-glioma
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  99. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Relative infectivity of the SARS-CoV-2 Omicron variant in human alveolar cells
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  100. Nov 2022
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    Identification of regenerating island-derived protein 3E in dogs
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    Transcription factor antagonism regulates heterogeneity in embryonic stem cell states
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  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FOXR2 is an epigenetically regulated pan-cancer oncogene that activates ETS transcriptional circuits
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  104. Oct 2022
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    Case report: A novel case of parental mosaicism in SMC1A gene causes inherited Cornelia de Lange syndrome
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    Human PSCs determine the competency of cerebral organoid differentiation via FGF signaling and epigenetic mechanisms
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    Induced retinal pigment epithelial cells with anti-epithelial-to-mesenchymal transition ability delay retinal degeneration
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  108. Sep 2022
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    Identification of candidate sex‐specific genomic regions in male and female Asian arowana genomes
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  110. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Loss of key endosymbiont genes may facilitate early host control of the chromatophore in Paulinella
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    The human mitochondrial genome contains a second light strand promoter
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  112. Aug 2022
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    Npas3 deficiency impairs cortical astrogenesis and induces autistic-like behaviors
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    Differential regulation of alternate promoter regions in Sox17 during endodermal and vascular endothelial development
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    The sage genome provides insight into the evolutionary dynamics of diterpene biosynthesis gene cluster in plants
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  116. Jul 2022
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    HMCES modulates the transcriptional regulation of nodal/activin and BMP signaling in mESCs
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  118. Jun 2022
  119. www.nature.com www.nature.com
    The first long-read nuclear genome assembly of Oryza australiensis, a wild rice from northern Australia
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  120. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Global-run on sequencing identifies Gm11967 as an Akt-dependent long noncoding RNA involved in insulin sensitivity
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  121. May 2022
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    Ribbon boosts ribosomal protein gene expression to coordinate organ form and function
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    H3-K27M-mutant nucleosomes interact with MLL1 to shape the glioma epigenetic landscape
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    KSHV episome tethering sites on host chromosomes and regulation of latency-lytic switch by CHD4
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  125. Apr 2022
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    An adult-stage transcriptional program for survival of serotonergic connectivity
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    HNF4A modulates glucocorticoid action in the liver
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  128. jeccr.biomedcentral.com jeccr.biomedcentral.com
    Growth factor independence underpins a paroxysmal, aggressive Wnt5aHigh/EphA2Low phenotype in glioblastoma stem cells, conducive to experimental combinatorial therapy
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      DOI: 10.1186/s13046-022-02333-1

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  129. www.sciencedirect.com www.sciencedirect.com
    Znhit1 controls meiotic initiation in male germ cells by coordinating with Stra8 to activate meiotic gene expression
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  130. Mar 2022
  131. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chromosome-length genome assembly and linkage map of a critically endangered Australian bird: the helmeted honeyeater
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  132. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Eco1-dependent cohesin acetylation anchors chromatin loops and cohesion to define functional meiotic chromosome domains
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    Metabolic incorporation of electron-rich ribonucleosides enhances APEX-seq for profiling spatially restricted nascent transcriptome
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  134. Feb 2022
  135. www.nature.com www.nature.com
    Global mapping of RNA G-quadruplexes (G4-RNAs) using G4RP-seq
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  136. www.sciencedirect.com www.sciencedirect.com
    Uncovering the mesendoderm gene regulatory network through multi-omic data integration
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    Histone H1 prevents non-CG methylation-mediated small RNA biogenesis in Arabidopsis heterochromatin
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    Widespread discrepancy in Nnt genotypes and genetic backgrounds complicates granzyme A and other knockout mouse studies
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  139. Jan 2022
  140. www.sciencedirect.com www.sciencedirect.com
    Dynamic chromatin state profiling reveals regulatory roles of auxin and cytokinin in shoot regeneration
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    Establishment of developmental gene silencing by ordered polycomb complex recruitment in early zebrafish embryos
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    Multimodal regulatory elements within a hormone-specific super enhancer control a heterogeneous transcriptional response
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    PRC1 sustains the integrity of neural fate in the absence of PRC2 function
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  144. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MAP3K7 loss drives enhanced androgen signaling and independently confers risk of recurrence in prostate cancer with joint loss of CHD1
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  145. Dec 2021
  146. www.sciencedirect.com www.sciencedirect.com
    piRNAs initiate transcriptional silencing of spermatogenic genes during C. elegans germline development
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    Histone deacetylase 3 represses cholesterol efflux during CD4+ T-cell activation
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    A bipartite element with allele-specific functions safeguards DNA methylation imprints at the Dlk1-Dio3 locus
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    Multilayer omics analysis reveals a non-classical retinoic acid signaling axis that regulates hematopoietic stem cell identity
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    A nascent polypeptide sequence modulates DnaA translation elongation in response to nutrient availability
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    Epigenomic and transcriptional profiling identifies impaired glyoxylate detoxification in NAFLD as a risk factor for hyperoxaluria
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    An essential role for the piRNA pathway in regulating the ribosomal RNA pool in C. elegans
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    CLOCKWORK ORANGE promotes CLOCK-CYCLE activation via the putative Drosophila ortholog of CLOCK INTERACTING PROTEIN CIRCADIAN
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    Glial pathology in a novel spontaneous mutant mouse of the Eif2b5 gene: a vanishing white matter disease model
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    BET Inhibition Induces HEXIM1- and RAD51-Dependent Conflicts between Transcription and Replication
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    ORY-1001, a Potent and Selective Covalent KDM1A Inhibitor, for the Treatment of Acute Leukemia
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    BRD4 Inhibition Is Synthetic Lethal with PARP Inhibitors through the Induction of Homologous Recombination Deficiency
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    Deletion of RBMX RGG/RG motif in Shashi-XLID syndrome leads to aberrant p53 activation and neuronal differentiation defects
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    Non-canonical Targets of HIF1a Impair Oligodendrocyte Progenitor Cell Function
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