336 Matching Annotations
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  3. Aug 2025
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    Cooperative control of neuron-specific repressive chromatin states by intellectual-disability-linked KDM1A and KDM5C demethylases
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    sciencedirect.com/science/article/pii/S2211124725009726
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    LINE-1 retrotransposons mediate cis-acting transcriptional control in human pluripotent stem cells and regulate early brain development
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    Transient gene melting governs the timing of oligodendrocyte maturation
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    Genetic Heterogeneity of Autism Spectrum Disorder: Identification of Five Novel Mutations (RIMS2, FOXG1, AUTS2, ZCCHC17, and SPTBN5) in Iranian Families via Whole-Exome and Whole-Genome Sequencing
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    Fibroblast bioelectric signaling drives hair growth
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    2025.08.06.668886v1.full-html.html
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    Distinct specificity and functions of PRC2 subcomplexes in human stem cells and cardiac differentiation
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    Whole-genome sequencing reveals three follicular lymphoma subtypes with distinct cell of origin and patient outcomes
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    Allelic bias contributes to heterogeneous phenotypes of NK cell deficiency
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    PARKIN protein-deficient iPSC line (FINi006-A) from an early-onset Parkinson’s disease female patient
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  14. Jul 2025
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    MyoD is Essential in Rhabdomyosarcoma by Promoting Survival Through Differentiation and CYLD
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    Validation of Guidelines for Genetic Investigation of Myeloid Neoplasms with Germline Predisposition: Results from a Prospective Cohort Study
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    Multiomics uncovers the epigenomic and transcriptomic response to viral and bacterial stimulation in turbot
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    A postnatal molecular switch drives activity-dependent maturation of parvalbumin interneurons
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    Requirement for Cyclin D1 Underlies Cell-Autonomous HIF2 Dependence in Kidney Cancer
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    The genome of Hippophae salicifolia provides new insights into the sexual differentiation of sea buckthorn
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    Mutant p53 exploits enhancers to elevate immunosuppressive chemokine expression and impair immune checkpoint inhibitors in pancreatic cancer
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  23. Jun 2025
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    Altered cofactor recruitment and nucleosome dynamics underlie bisphenol A’s impact on ERα-mediated transcriptional bursting
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    Functional assessment of all ATM SNVs using prime editing and deep learning
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    Cold-inducible GOT1 activates the malate-aspartate shuttle in brown adipose tissue to support fuel preference for fatty acids
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    Spatial–Temporal Diversity of Extrachromosomal DNA Shapes Urothelial Carcinoma Evolution and the Tumor Immune Microenvironment
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  30. May 2025
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    Mediator regulates transcriptional termination through crosstalk with pre-mRNA 3′ end processing factors
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    Alternative mRNA splicing in anthracycline-induced cardiomyopathy – a COG-ALTE03N1 report
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    The genomic landscape of benign and malignant thyroid tumors from individuals carrying germline PTEN variants is distinct from sporadic thyroid cancers
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    Transcription factor cooperativity at a GATA3 tandem DNA sequence determines oncogenic enhancer-mediated activation
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  37. Apr 2025
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    Metabolite-dependent m6A methylation driven by mechanotransduction-metabolism-epitranscriptomics axis promotes bone development and regeneration
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    Germline Pathogenic DROSHA Variants Are Linked to Pineoblastoma and Wilms Tumor Predisposition
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    Intestinal secretory differentiation reflects niche-driven phenotypic and epigenetic plasticity of a common signal-responsive terminal cell
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    Stratified Medicine Pediatrics: Cell-Free DNA and Serial Tumor Sequencing Identifies Subtype-Specific Cancer Evolution and Epigenetic States
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  42. Mar 2025
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    Antagonistic roles for MITF and TFE3 in melanoma plasticity
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    m6A deficiency impairs hypothalamic neurogenesis of feeding-related neurons in mice and human organoids and leads to adult obesity in mice
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    PIF/harbinger transposon-derived protein promotes 7SL expression to enhance pathogen resistance
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    Nuclear Argonaute protein NRDE-3 switches small RNA partners during embryogenesis to mediate temporal-specific gene regulatory activity
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  47. Feb 2025
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    Fusion oncoproteins and cooperating mutations define disease phenotypes in NUP98-rearranged leukemia
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    Enhancing inbreeding estimation and global conservation insights through chromosome-level assemblies of the Chinese and Malayan pangolin
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    Systematic characterization of p53-regulated long non-coding RNAs across human cancers reveals remarkable heterogeneity among different tumor types
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    Epigenome reprogramming through H3K27 and H3K4 trimethylation as a resistance mechanism to DNA methylation inhibition in BRAFV600E-mutated colorectal cancer
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    Histone H4 acetylation differentially modulates proliferation in adult oligodendrocyte progenitors
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  54. Jan 2025
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    Natural killer cell–mediated cytotoxicity shapes the clonal evolution of B cell leukaemia
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    KDM6B-dependent epigenetic programming of uterine fibroblasts in early pregnancy regulates parturition timing in mice
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    A single-nuclei transcriptome census of the Arabidopsis maturing root identifies that MYB67 controls phellem cell maturation
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    Efficacy of CBP/p300 Dual Inhibitors against De-repression of KREMEN2 in cBAF-Deficient Cancers
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    Beyond HRD Status: Unraveling Genetic Variants Impacting PARP Inhibitor Sensitivity in Advanced Ovarian Cancer
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  60. Dec 2024
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    Disrupted methionine cycle triggers muscle atrophy in cancer cachexia through epigenetic regulation of REDD1
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    Single cell long read whole genome sequencing reveals somatic transposon activity in human brain
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    Full-length direct RNA sequencing uncovers stress granule-dependent RNA decay upon cellular stress
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    Tubulin sequence divergence is associated with the use of distinct microtubule regulators
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    Satb1 regulates Contactin 5 to pattern dendrites of a mammalian retinal ganglion cell
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    The telomere-to-telomere (T2T) genome provides insights into the evolution of specialized centromere sequences in sandalwood
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    Reciprocal inhibition of NOTCH and SOX2 shapes tumor cell plasticity and therapeutic escape in triple-negative breast cancer
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    Epigenetic and Oncogenic Inhibitors Cooperatively Drive Differentiation and Kill KRAS-Mutant Colorectal Cancers
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    DNA hypomethylation promotes UHRF1-and SUV39H1/H2-dependent crosstalk between H3K18ub and H3K9me3 to reinforce heterochromatin states
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    Biliverdinuria Caused by Exonic BLVRA Deletions in Two Dogs with Green Urine
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  72. Nov 2024
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  74. Oct 2024
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    Clinical value of liquid biopsy in FGFR2 fusion-positive cholangiocarcinoma patients during targeted therapy
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    Hypoxia-Induced Long Noncoding RNA HIF1A-AS2 Regulates Stability of MHC Class I Protein in Head and Neck Cancer
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    Use of synthetic circular RNA spike-ins (SynCRS) for normalization of circular RNA sequencing data
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  78. Sep 2024
  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    High-speed whole-genome sequencing of a Whippet: Rapid chromosome-level assembly and annotation of an extremely fast dog’s genome
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  80. Aug 2024
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    CRISPR screening uncovers a long-range enhancer for ONECUT1 in pancreatic differentiation and links a diabetes risk variant
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    Members of an array of zinc-finger proteins specify distinct Hox chromatin boundaries
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    Transient Differentiation-State Plasticity Occurs During Acute Lymphoblastic Leukemia Initiation
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    Genomic dynamics of the Lower Yellow River Valley since the Early Neolithic
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    SOX10 loss sensitizes melanoma cells to cytokine-mediated inflammatory cell death
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  86. Jul 2024
  87. www.cell.com www.cell.com
    Innate immune training restores pro-reparative myeloid functions to promote remyelination in the aged central nervous system
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    The primitive endoderm supports lineage plasticity to enable regulative development
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    Stochastic RNA editing of the Complexin C-terminus within single neurons regulates neurotransmitter release
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    Loss of ADAM29 does not affect viability and fertility in mice but improves wound healing
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  91. Jun 2024
  92. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Impacts of in-vitro zebularine treatment on genome-wide DNA methylation and transcriptomic profiles in Salix purpurea L.
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    onlinelibrary.wiley.com/doi/10.1111/ppl.14403
  93. May 2024
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    Reciprocal conversion between annual and polycarpic perennial flowering behavior in the Brassicaceae
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    Heterochromatic 3D genome organization is directed by HP1a- and H3K9-dependent and independent mechanisms
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    T-bet deficiency and Hic1 induction override TGF-β-dependency in the formation of CD103+ intestine-resident memory CD8+ T cells
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    The CD8+ T cell tolerance checkpoint triggers a distinct differentiation state defined by protein translation defects
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    Integrative molecular analyses of the MD Anderson prostate cancer patient-derived xenograft (MDA PCa PDX) series
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    Global mapping of RNA G-quadruplexes (G4-RNAs) using G4RP-seq
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    nature.com/articles/s41596-021-00671-6
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    Uncovering the mesendoderm gene regulatory network through multi-omic data integration
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  214. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Histone H1 prevents non-CG methylation-mediated small RNA biogenesis in Arabidopsis heterochromatin
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    ncbi.nlm.nih.gov/pmc/articles/PMC8828055/
  215. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Widespread discrepancy in Nnt genotypes and genetic backgrounds complicates granzyme A and other knockout mouse studies
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    ncbi.nlm.nih.gov/pmc/articles/PMC8816380/
  216. Jan 2022
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    Dynamic chromatin state profiling reveals regulatory roles of auxin and cytokinin in shoot regeneration
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  218. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Establishment of developmental gene silencing by ordered polycomb complex recruitment in early zebrafish embryos
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    Multimodal regulatory elements within a hormone-specific super enhancer control a heterogeneous transcriptional response
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  220. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PRC1 sustains the integrity of neural fate in the absence of PRC2 function
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    ncbi.nlm.nih.gov/pmc/articles/PMC8765755/
  221. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MAP3K7 loss drives enhanced androgen signaling and independently confers risk of recurrence in prostate cancer with joint loss of CHD1
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    ncbi.nlm.nih.gov/pmc/articles/PMC8254790/
  222. Dec 2021
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    piRNAs initiate transcriptional silencing of spermatogenic genes during C. elegans germline development
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  224. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Histone deacetylase 3 represses cholesterol efflux during CD4+ T-cell activation
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    Pre-existing chromatin accessibility and gene expression differences among naive CD4+ T cells influence effector potential
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  226. Nov 2021
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    Acsbg1-dependent mitochondrial fitness is a metabolic checkpoint for tissue Treg cell homeostasis
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  228. Oct 2021
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    A bipartite element with allele-specific functions safeguards DNA methylation imprints at the Dlk1-Dio3 locus
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    Multilayer omics analysis reveals a non-classical retinoic acid signaling axis that regulates hematopoietic stem cell identity
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    PIWI-mediated control of tissue-specific transposons is essential for somatic cell differentiation
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    sciencedirect.com/science/article/pii/S2211124721012304
  232. Sep 2021
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    H3K4 di-methylation governs smooth muscle lineage identity and promotes vascular homeostasis by restraining plasticity
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    Niche partitioning facilitates coexistence of closely related honey bee gut bacteria
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    A nascent polypeptide sequence modulates DnaA translation elongation in response to nutrient availability
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  236. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HBO1-MLL interaction promotes AF4/ENL/P-TEFb-mediated leukemogenesis
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  237. Aug 2021
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    Epigenomic and transcriptional profiling identifies impaired glyoxylate detoxification in NAFLD as a risk factor for hyperoxaluria
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    An essential role for the piRNA pathway in regulating the ribosomal RNA pool in C. elegans
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    Enhancer RNA m6A methylation facilitates transcriptional condensate formation and gene activation
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    CLOCKWORK ORANGE promotes CLOCK-CYCLE activation via the putative Drosophila ortholog of CLOCK INTERACTING PROTEIN CIRCADIAN
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