376 Matching Annotations
  1. Nov 2024
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Functional implications of the exon 9 splice insert in GluK1 kainate receptors
    1
    1. scibot 10 Nov 2024
      RRID:SCR_014224

      DOI: 10.7554/eLife.89755

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    pmc.ncbi.nlm.nih.gov/articles/PMC11540303/
  3. Oct 2024
  4. www.sciencedirect.com www.sciencedirect.com
    Filament formation activates protease and ring nuclease activities of CRISPR Lon-SAVED
    1
    1. scibot 04 Oct 2024
      RRID:SCR_014224

      DOI: 10.1016/j.molcel.2024.09.002

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    sciencedirect.com/science/article/pii/S1097276524007354
  5. Sep 2024
  6. www.biorxiv.org www.biorxiv.org
    Type-II kinase inhibitors that target Parkinson’s Disease-associated LRRK2
    1
    1. scibot 28 Sep 2024
      RRID:SCR_014224

      DOI: 10.1101/2024.09.17.613365

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    biorxiv.org/content/10.1101/2024.09.17.613365v1
  7. www.sciencedirect.com www.sciencedirect.com
    Discovery and characterization of a pan-betacoronavirus S2-binding antibody
    1
    1. scibot 27 Sep 2024
      RRID:SCR_014224

      DOI: 10.1016/j.str.2024.08.022

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    sciencedirect.com/science/article/pii/S0969212624003691
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    Conformational Plasticity in the HIV-1 Fusion Peptide Facilitates Recognition by Broadly Neutralizing Antibodies
    1
    1. scibot 25 Sep 2024
      RRID:SCR_014224

      DOI: 10.1016/j.chom.2019.04.011

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    sciencedirect.com/science/article/pii/S1931312819302148
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    Dynamic allostery drives autocrine and paracrine TGF-β signaling
    1
    1. scibot 17 Sep 2024
      RRID:SCR_014224

      DOI: 10.1016/j.cell.2024.08.036

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    sciencedirect.com/science/article/pii/S0092867424009656
  10. Aug 2024
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structure of the human heparan-α-glucosaminide N-acetyltransferase (HGSNAT)
    1
    1. scibot 30 Aug 2024
      RRID:SCR_014224

      DOI: 10.7554/eLife.93510

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    ncbi.nlm.nih.gov/pmc/articles/PMC11357348/
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    Conservation and specialization of the Ycf2-FtsHi chloroplast protein import motor in green algae
    1
    1. scibot 28 Aug 2024
      RRID:SCR_014224

      DOI: 10.1016/j.cell.2024.08.002

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    sciencedirect.com/science/article/pii/S0092867424008936
  13. www.sciencedirect.com www.sciencedirect.com
    Structural insights into the chloroplast protein import in land plants
    1
    1. scibot 28 Aug 2024
      RRID:SCR_014224

      DOI: 10.1016/j.cell.2024.08.003

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    sciencedirect.com/science/article/pii/S0092867424008948
  14. www.sciencedirect.com www.sciencedirect.com
    Viral DNA polymerase structures reveal mechanisms of antiviral drug resistance
    1
    1. scibot 28 Aug 2024
      RRID:SCR_014224

      DOI: 10.1016/j.cell.2024.07.048

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    sciencedirect.com/science/article/pii/S0092867424008420
  15. www.sciencedirect.com www.sciencedirect.com
    Hybrid immunity to SARS-CoV-2 arises from serological recall of IgG antibodies distinctly imprinted by infection or vaccination
    1
    1. scibot 18 Aug 2024
      RRID:SCR_014224

      DOI: 10.1016/j.xcrm.2024.101668

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    sciencedirect.com/science/article/pii/S2666379124003823
  16. europepmc.orghttp europepmc.orghttp
    Structural Basis for a Safety-Belt Mechanism That Anchors Condensin to Chromosomes
    1
    1. scibot 02 Aug 2024
      Phenix suite

      DOI: 10.1016/j.cell.2017.09.008

      Resource: Phenix (RRID:SCR_014224)

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    europepmc.orghttp//europepmc.org/articles/PMC5651216/
  17. www.proquest.com www.proquest.com
    Mechanism of Ca2+ transport by ferroportin - ProQuest
    1
    1. scibot 02 Aug 2024
      RRID:SCR_014224

      DOI: 10.7554/eLife.82947

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    proquest.com/docview/2771288630
  18. Jul 2024
  19. www.sciencedirect.com www.sciencedirect.com
    Structure of the Hir histone chaperone complex
    1
    1. scibot 24 Jul 2024
      RRID:SCR_014224

      DOI: 10.1016/j.molcel.2024.05.031

      Resource: Phenix (RRID:SCR_014224)

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    sciencedirect.com/science/article/pii/S1097276524004787
  20. www.sciencedirect.com www.sciencedirect.com
    An IDR-dependent mechanism for nuclear receptor control of Mediator interaction with RNA polymerase II
    1
    1. scibot 19 Jul 2024
      RRID:SCR_014224

      DOI: 10.1016/j.molcel.2024.06.006

      Resource: Phenix (RRID:SCR_014224)

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    sciencedirect.com/science/article/pii/S1097276524004842
  21. www.sciencedirect.com www.sciencedirect.com
    Crimean-Congo hemorrhagic fever survivors elicit protective non-neutralizing antibodies that target 11 overlapping regions on glycoprotein GP38
    1
    1. scibot 16 Jul 2024
      RRID:SCR_014224

      DOI: 10.1016/j.celrep.2024.114502

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    sciencedirect.com/science/article/pii/S2211124724008313
  22. Jun 2024
  23. www.sciencedirect.com www.sciencedirect.com
    A designed ankyrin-repeat protein that targets Parkinson’s disease-associated LRRK2
    1
    1. scibot 21 Jun 2024
      RRID:SCR_014224

      DOI: 10.1016/j.jbc.2024.107469

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    sciencedirect.com/science/article/pii/S0021925824019707
  24. www.sciencedirect.com www.sciencedirect.com
    Mechanism of heterochromatin remodeling revealed by the DDM1 bound nucleosome structures
    1
    1. scibot 21 Jun 2024
      RRID:SCR_014224

      DOI: 10.1016/j.str.2024.05.013

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    sciencedirect.com/science/article/pii/S0969212624001904
  25. www.sciencedirect.com www.sciencedirect.com
    POT1 recruits and regulates CST-Polα/primase at human telomeres
    1
    1. scibot 05 Jun 2024
      RRID:SCR_014224

      DOI: 10.1016/j.cell.2024.05.002

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    sciencedirect.com/science/article/pii/S0092867424004938
  26. www.sciencedirect.com www.sciencedirect.com
    Cryo-electron tomography reveals the packaging pattern of RuBisCOs in Synechococcus β-carboxysome
    1
    1. scibot 04 Jun 2024
      RRID:SCR_014224

      DOI: 10.1016/j.str.2024.05.007

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    sciencedirect.com/science/article/pii/S0969212624001849
  27. May 2024
  28. www.sciencedirect.com www.sciencedirect.com
    A targeted single mutation in influenza A virus universal epitope transforms immunogenicity and protective immunity via CD4+ T cell activation
    1
    1. scibot 31 May 2024
      RRID:SCR_014224

      DOI: 10.1016/j.celrep.2024.114259

      Resource: Phenix (RRID:SCR_014224)

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    sciencedirect.com/science/article/pii/S2211124724005874
  29. Apr 2024
  30. www.sciencedirect.com www.sciencedirect.com
    Eliciting a single amino acid change by vaccination generates antibody protection against group 1 and group 2 influenza A viruses
    1
    1. scibot 26 Apr 2024
      RRID:SCR_014224

      DOI: 10.1016/j.immuni.2024.03.022

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    sciencedirect.com/science/article/pii/S1074761324001432
  31. www.nature.com www.nature.com
    Visualizing chaperone-mediated multistep assembly of the human 20S proteasome
    1
    1. scibot 11 Apr 2024
      RRID:SCR_014224

      DOI: 10.1038/s41594-024-01268-9

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    nature.com/articles/s41594-024-01268-9
  32. www.sciencedirect.com www.sciencedirect.com
    Staphylococcus aureus skin colonization is mediated by SasG lectin variation
    1
    1. scibot 04 Apr 2024
      RRID:SCR_014224

      DOI: 10.1016/j.celrep.2024.114022

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    sciencedirect.com/science/article/pii/S2211124724003504
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural basis of ligand specificity and channel activation in an insect gustatory receptor
    1
    1. scibot 04 Apr 2024
      RRID:SCR_014224

      DOI: 10.1016/j.celrep.2024.114035

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    ncbi.nlm.nih.gov/pmc/articles/PMC11100771/
  34. Mar 2024
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural mechanisms for VMAT2 inhibition by tetrabenazine
    1
    1. scibot 27 Mar 2024
      RRID:SCR_014224

      DOI: 10.7554/eLife.91973

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    ncbi.nlm.nih.gov/pmc/articles/PMC10959523/
  36. www.sciencedirect.com www.sciencedirect.com
    Convergent evolution and targeting of diverse E2 epitopes by human broadly neutralizing antibodies are associated with HCV clearance
    1
    1. scibot 22 Mar 2024
      RRID: SCR_014224

      DOI: 10.1016/j.immuni.2024.03.001

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    sciencedirect.com/science/article/pii/S1074761324000979
  37. www.sciencedirect.com www.sciencedirect.com
    ZP2 cleavage blocks polyspermy by modulating the architecture of the egg coat
    2
    1. scibot 15 Mar 2024
      RRID:SCR_014224

      DOI: 10.1016/j.cell.2024.02.013

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    2. scibot 15 Mar 2024
      RRID:SCR_014224

      DOI: 10.1016/j.cell.2024.02.013

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    sciencedirect.com/science/article/pii/S009286742400179X
  38. www.sciencedirect.com www.sciencedirect.com
    Structure of the plant plastid-encoded RNA polymerase
    2
    1. scibot 01 Mar 2024
      RRID:SCR_014224

      DOI: 10.1016/j.cell.2024.01.036

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    2. scibot 01 Mar 2024
      RRID:SCR_014224

      DOI: 10.1016/j.cell.2024.01.036

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    sciencedirect.com/science/article/pii/S009286742400103X
  39. www.sciencedirect.com www.sciencedirect.com
    Cryo-EM structures of the plant plastid-encoded RNA polymerase
    1
    1. scibot 01 Mar 2024
      RRID:SCR_014224

      DOI: 10.1016/j.cell.2024.01.026

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    sciencedirect.com/science/article/pii/S0092867424000631
  40. Feb 2024
  41. elifesciences.org elifesciences.org
    Multiple serine transposase dimers assemble the transposon-end synaptic complex during IS607-family transposition
    1
    1. scibot 08 Feb 2024
      RRID:SCR_014224

      DOI: 10.7554/eLife.39611

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    elifesciences.org/articles/39611
  42. Dec 2023
  43. www.sciencedirect.com www.sciencedirect.com
    The MHC-E peptide ligands for checkpoint CD94/NKG2A are governed by inflammatory signals, whereas LILRB1/2 receptors are peptide indifferent
    1
    1. scibot 20 Dec 2023
      RRID:SCR_014224

      DOI: 10.1016/j.celrep.2023.113516

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    sciencedirect.com/science/article/pii/S2211124723015280
  44. www.sciencedirect.com www.sciencedirect.com
    Titin domains with reduced core hydrophobicity cause dilated cardiomyopathy
    1
    1. scibot 20 Dec 2023
      RRID:SCR_014224

      DOI: 10.1016/j.celrep.2023.113490

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    sciencedirect.com/science/article/pii/S2211124723015024
  45. www.sciencedirect.com www.sciencedirect.com
    Assembly-mediated activation of the SIR2-HerA supramolecular complex for anti-phage defense
    1
    1. scibot 16 Dec 2023
      RRID:SCR_014224

      DOI: 10.1016/j.molcel.2023.11.007

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    sciencedirect.com/science/article/pii/S1097276523009498
  46. Nov 2023
  47. www.sciencedirect.com www.sciencedirect.com
    Leveraging vaccination-induced protective antibodies to define conserved epitopes on influenza N2 neuraminidase
    1
    1. scibot 18 Nov 2023
      RRID:SCR_014224

      DOI: 10.1016/j.immuni.2023.10.005

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    sciencedirect.com/science/article/pii/S1074761323004454
  48. www.sciencedirect.com www.sciencedirect.com
    Architecture of the bacteriophage lambda tail
    1
    1. scibot 03 Nov 2023
      RRID:SCR_014224

      DOI: 10.1016/j.str.2023.10.006

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    sciencedirect.com/science/article/pii/S0969212623003635
  49. www.sciencedirect.com www.sciencedirect.com
    Discovery of highly neutralizing human antibodies targeting Pseudomonas aeruginosa
    1
    1. scibot 03 Nov 2023
      SCR_014224

      DOI: 10.1016/j.cell.2023.10.002

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    sciencedirect.com/science/article/pii/S009286742301084X
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Energy coupling and stoichiometry of Zn2+/H+ antiport by the prokaryotic cation diffusion facilitator YiiP
    1
    1. scibot 02 Nov 2023
      RRID:SCR_014224

      DOI: 10.7554/eLife.87167

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    ncbi.nlm.nih.gov/pmc/articles/PMC10617992/
  51. Oct 2023
  52. www.sciencedirect.com www.sciencedirect.com
    KANK1 shapes focal adhesions by orchestrating protein binding, mechanical force sensing, and phase separation
    1
    1. scibot 28 Oct 2023
      RRID:SCR_014224

      DOI: 10.1016/j.celrep.2023.113321

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    sciencedirect.com/science/article/pii/S2211124723013335
  53. www.nature.com www.nature.com
    A Legionella toxin exhibits tRNA mimicry and glycosyl transferase activity to target the translation machinery and trigger a ribotoxic stress response
    2
    1. scibot 20 Oct 2023
      RRID:SCR_014224

      DOI: 10.1038/s41556-023-01248-z

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    2. scibot 20 Oct 2023
      RRID:SCR_014224

      DOI: 10.1038/s41556-023-01248-z

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    nature.com/articles/s41556-023-01248-z
  54. Sep 2023
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RLY-4008, the first highly selective FGFR2 inhibitor with activity across FGFR2 alterations and resistance mutations
    1
    1. scibot 08 Sep 2023
      RRID:SCR_014224

      DOI: 10.1158/2159-8290.CD-23-0475

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  56. Aug 2023
  57. 52.53.155.43 52.53.155.43
    Recognition determinants of improved HIV-1 neutralization by a heavy chain matured pediatric antibody
    1
    1. scibot 17 Aug 2023
      RRID:SCR_014224

      DOI: 10.1016/j.isci.2023.107579

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  58. 52.53.155.43 52.53.155.43
    Structural insights into anion selectivity and activation mechanism of LRRC8 volume-regulated anion channels
    2
    1. scibot 12 Aug 2023
      RRID:SCR_014224

      DOI: 10.1016/j.celrep.2023.112926

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      DOI: 10.1016/j.celrep.2023.112926

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  59. Jul 2023
  60. www.sciencedirect.com www.sciencedirect.com
    Structural definition of HLA class II-presented SARS-CoV-2 epitopes reveals a mechanism to escape pre-existing CD4+ T cell immunity
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    1. scibot 21 Jul 2023
      RRID:SCR_014224

      DOI: 10.1016/j.celrep.2023.112827

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  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sterol derivative binding to the orthosteric site causes conformational changes in an invertebrate Cys-loop receptor
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      DOI: 10.7554/eLife.86029

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  62. 52.53.155.43 52.53.155.43
    cd-23-0475-html.html
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    1. scibot 13 Jul 2023
      RRID:SCR_014224

      DOI: 10.1158/2159-8290.cd-23-0475

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  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural and functional properties of the transporter SLC26A6 reveal mechanism of coupled anion exchange
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    1. scibot 12 Jul 2023
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      DOI: 10.7554/eLife.87178

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  64. Jun 2023
  65. www.sciencedirect.com www.sciencedirect.com
    A structural blueprint for interleukin-21 signal modulation
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    1. scibot 21 Jun 2023
      SCR_014224

      DOI: 10.1016/j.celrep.2023.112657

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  66. www.sciencedirect.com www.sciencedirect.com
    Type IV-A CRISPR-Csf complex: Assembly, dsDNA targeting, and CasDinG recruitment
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    1. scibot 21 Jun 2023
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      DOI: 10.1016/j.molcel.2023.05.036

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  67. www.sciencedirect.com www.sciencedirect.com
    New scaffolds for type II JAK2 inhibitors overcome the acquired G993A resistance mutation
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      DOI: 10.1016/j.chembiol.2023.05.007

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  68. May 2023
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    High-resolution structures with bound Mn2+ and Cd2+ map the metal import pathway in an Nramp transporter
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    1. scibot 18 May 2023
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      DOI: 10.7554/eLife.84006

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  70. www.sciencedirect.com www.sciencedirect.com
    Molecular basis of SARS-CoV-2 Omicron variant evasion from shared neutralizing antibody response
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      DOI: 10.1016/j.str.2023.04.010

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  71. Apr 2023
  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cryo-EM structure of the endothelin-1-ETB-Gi complex
    1
    1. scibot 29 Apr 2023
      RRID:SCR_014224

      DOI: 10.7554/eLife.85821

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    ncbi.nlm.nih.gov/pmc/articles/PMC10129325/
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural and functional properties of a plant NRAMP-related aluminum transporter
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    1. scibot 27 Apr 2023
      RRID:SCR_014224

      DOI: 10.7554/eLife.85641

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  74. www.sciencedirect.com www.sciencedirect.com
    Machine learning predictions of MHC-II specificities reveal alternative binding mode of class II epitopes
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    1. scibot 06 Apr 2023
      RRID:SCR_014224

      DOI: 10.1016/j.immuni.2023.03.009

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    sciencedirect.com/science/article/pii/S1074761323001292
  75. Mar 2023
  76. www.sciencedirect.com www.sciencedirect.com
    Immunodominant surface epitopes power immune evasion in the African trypanosome
    1
    1. scibot 28 Mar 2023
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      DOI: 10.1016/j.celrep.2023.112262

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    sciencedirect.com/science/article/pii/S2211124723002735
  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cryo-EM structures of mitochondrial respiratory complex I from Drosophila melanogaster
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    1. scibot 05 Mar 2023
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      DOI: 10.7554/eLife.84424

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    ncbi.nlm.nih.gov/pmc/articles/PMC9977279/
  78. Feb 2023
  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural basis for ATG9A recruitment to the ULK1 complex in mitophagy initiation
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    1. scibot 17 Feb 2023
      RRID:SCR_0142294

      DOI: 10.1126/sciadv.adg2997

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  80. www.sciencedirect.com www.sciencedirect.com
    Structural basis of a transcription pre-initiation complex on a divergent promoter
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      RRID:SCR_014224

      DOI: 10.1016/j.molcel.2023.01.011

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  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mechanism of Ca2+ transport by ferroportin
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    1. scibot 01 Feb 2023
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      DOI: 10.7554/eLife.82947

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    ncbi.nlm.nih.gov/pmc/articles/PMC9883014/
  82. Jan 2023
  83. www.sciencedirect.com www.sciencedirect.com
    Nucleosome dyad determines the H1 C-terminus collapse on distinct DNA arms
    1
    1. scibot 07 Jan 2023
      RRID:SCR_014224

      DOI: 10.1016/j.str.2022.12.005

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    sciencedirect.com/science/article/pii/S0969212622004919
  84. Dec 2022
  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structure of human phagocyte NADPH oxidase in the resting state
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    1. scibot 02 Dec 2022
      RRID:SCR_014224

      DOI: 10.7554/eLife.83743

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    ncbi.nlm.nih.gov/pmc/articles/PMC9711523/
  86. Nov 2022
  87. www.sciencedirect.com www.sciencedirect.com
    Structure of a TOC-TIC supercomplex spanning two chloroplast envelope membranes
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    1. scibot 22 Nov 2022
      RRID:SCR_014224

      DOI: 10.1016/j.cell.2022.10.030

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    sciencedirect.com/science/article/pii/S0092867422013769
  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neutralizing monoclonal antibodies elicited by mosaic RBD nanoparticles bind conserved sarbecovirus epitopes
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      DOI: 10.1016/j.immuni.2022.10.019

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    ncbi.nlm.nih.gov/pmc/articles/PMC9606073/
  89. www.sciencedirect.com www.sciencedirect.com
    IL-17-induced dimerization of IL-17RA drives the formation of the IL-17 signalosome to potentiate signaling
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      DOI: 10.1016/j.celrep.2022.111489

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    sciencedirect.com/science/article/pii/S2211124722013390
  90. Oct 2022
  91. www.sciencedirect.com www.sciencedirect.com
    BefA, a microbiota-secreted membrane disrupter, disseminates to the pancreas and increases β cell mass
    1
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      DOI: 10.1016/j.cmet.2022.09.001

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    sciencedirect.com/science/article/pii/S1550413122003916
  92. Sep 2022
  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Aminomethanesulfonic acid illuminates the boundary between full and partial agonists of the pentameric glycine receptor
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      DOI: 10.7554/eLife.79148

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    ncbi.nlm.nih.gov/pmc/articles/PMC9462852/
  94. Aug 2022
  95. www.sciencedirect.com www.sciencedirect.com
    Structure of a fully assembled tumor-specific T cell receptor ligated by pMHC
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      DOI: 10.1016/j.cell.2022.07.010

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    sciencedirect.com/science/article/pii/S0092867422009138
  96. Jul 2022
  97. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Conserved structural elements specialize ATAD1 as a membrane protein extraction machine
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      DOI: 10.7554/eLife.73941

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    ncbi.nlm.nih.gov/pmc/articles/PMC9273213/
  98. Jun 2022
  99. www.sciencedirect.com www.sciencedirect.com
    Rational exploration of fold atlas for human solute carrier proteins
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      DOI: 10.1016/j.str.2022.05.015

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  100. www.sciencedirect.com www.sciencedirect.com
    Structural basis for RNA surveillance by the human nuclear exosome targeting (NEXT) complex
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      DOI: 10.1016/j.cell.2022.04.016

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    sciencedirect.com/science/article/pii/S0092867422004639
  101. May 2022
  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Selective inhibition reveals the regulatory function of DYRK2 in protein synthesis and calcium entry
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    1. scibot 21 May 2022
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      DOI: 10.7554/eLife.77696

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    ncbi.nlm.nih.gov/pmc/articles/PMC9113749/
  103. Apr 2022
  104. www.sciencedirect.com www.sciencedirect.com
    Basis for drug selectivity of plasmepsin IX and X inhibition in Plasmodium falciparum and vivax
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      DOI: 10.1016/j.str.2022.03.018

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  105. www.sciencedirect.com www.sciencedirect.com
    RPAP2 regulates a transcription initiation checkpoint by inhibiting assembly of pre-initiation complex
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      DOI: 10.1016/j.celrep.2022.110732

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    sciencedirect.com/science/article/pii/S2211124722004934
  106. www.sciencedirect.com www.sciencedirect.com
    Structure of the poxvirus decapping enzyme D9 reveals its mechanism of cap recognition and catalysis
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      DOI: 10.1016/j.str.2022.02.012

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  107. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Analysis Of Memory B Cells Identifies Conserved Neutralizing Epitopes On The N-Terminal Domain Of Variant SARS-Cov-2 Spike Proteins
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      DOI: 10.1016/j.immuni.2022.04.003

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  108. Mar 2022
  109. www.cell.com www.cell.com
    Facile discovery of surrogate cytokine agonists
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      DOI: 10.1016/j.cell.2022.02.025

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    cell.com/cell/fulltext/S0092-8674(22)00247-1
  110. www.sciencedirect.com www.sciencedirect.com
    Asymmetric and non-stoichiometric glycoprotein recognition by two distinct antibodies results in broad protection against ebolaviruses
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      DOI: 10.1016/j.cell.2022.02.023

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  111. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural basis for an unprecedented enzymatic alkylation in cylindrocyclophane biosynthesis
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      DOI: 10.7554/eLife.75761

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  112. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural basis of nanobodies neutralizing SARS-CoV-2 variants
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  113. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Crystals of TELSAM–target protein fusions that exhibit minimal crystal contacts and lack direct inter-TELSAM contacts
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      DOI: 10.1098/rsob.210271

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  114. www.sciencedirect.com www.sciencedirect.com
    Structural basis for the catalytic activity of filamentous human serine beta-lactamase-like protein LACTB
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  115. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structure and ion-release mechanism of PIB-4-type ATPases
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  116. www.sciencedirect.com www.sciencedirect.com
    Structural insights into DNMT5-mediated ATP-dependent high-fidelity epigenome maintenance
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  117. www.sciencedirect.com www.sciencedirect.com
    Structures of SAS-6 coiled coil hold implications for the polarity of the centriolar cartwheel
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  118. www.sciencedirect.com www.sciencedirect.com
    Structural basis for catalyzed assembly of the Sonic hedgehog–Patched1 signaling complex
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  119. Feb 2022
  120. elifesciences.org elifesciences.org
    Fluorescence activation mechanism and imaging of drug permeation with new sensors for smoking-cessation ligands
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  121. elifesciences.org elifesciences.org
    Structural basis of Plasmodium vivax inhibition by antibodies binding to the circumsporozoite protein repeats
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  122. elifesciences.org elifesciences.org
    Structural and functional properties of a magnesium transporter of the SLC11/NRAMP family
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  123. Jan 2022
  124. elifesciences.org elifesciences.org
    Nanofluidic chips for cryo-EM structure determination from picoliter sample volumes
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  125. www.sciencedirect.com www.sciencedirect.com
    Structural basis of bacteriophage lambda capsid maturation
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  126. www.sciencedirect.com www.sciencedirect.com
    Structural visualization of de novo transcription initiation by Saccharomyces cerevisiae RNA polymerase II
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  127. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neurotoxin-mediated potent activation of the axon degeneration regulator SARM1
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      DOI: 10.7554/eLife.72823

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  128. Dec 2021
  129. www.sciencedirect.com www.sciencedirect.com
    Rational engineering enables co-crystallization and structural determination of the HIV-1 matrix-tRNA complex
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      DOI: 10.1016/j.xpro.2021.101056

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  130. Nov 2021
  131. www.sciencedirect.com www.sciencedirect.com
    Structure and assembly pattern of a freshwater short-tailed cyanophage Pam1
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  132. Oct 2021
  133. www.sciencedirect.com www.sciencedirect.com
    Pan-ebolavirus protective therapy by two multifunctional human antibodies
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      DOI: 10.1016/j.cell.2021.09.035

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  134. www.sciencedirect.com www.sciencedirect.com
    Conserved heterodimeric GTPase Rbg1/Tma46 promotes efficient translation in eukaryotic cells
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  135. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural insights into the cis and trans assembly of human trophoblast cell surface antigen 2
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      DOI: 10.1016/j.isci.2021.103190

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  136. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural characterization of NrnC identifies unifying features of dinucleotidases
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  137. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural insights into the activation of human calcium-sensing receptor
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      DOI: 10.7554/eLife.68578

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  138. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TMEM120A contains a specific coenzyme A-binding site and might not mediate poking- or stretch-induced channel activities in cells
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      DOI: 10.7554/eLife.71474

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  139. Sep 2021
  140. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structure and dynamics of the chromatin remodeler ALC1 bound to a PARylated nucleosome
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    Structural basis and regulation of the reductive stress response
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    Atypical TNF-TNFR superfamily binding interface in the GITR-GITRL complex for T cell activation
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    Broad cross-reactivity across sarbecoviruses exhibited by a subset of COVID-19 donor-derived neutralizing antibodies
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  144. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Regulation of human mTOR complexes by DEPTOR
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      DOI: 10.7554/eLife.70871

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    Structural snapshots of TRPV1 reveal mechanism of polymodal functionality
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    High-resolution structure of the membrane-embedded skeletal muscle ryanodine receptor
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  147. Aug 2021
  148. elifesciences.org elifesciences.org
    Functional development of a V3/glycan-specific broadly neutralizing antibody isolated from a case of HIV superinfection
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      DOI: 10.7554/eLife.68110

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  149. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    McsB forms a gated kinase chamber to mark aberrant bacterial proteins for degradation
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  150. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structure of Escherichia coli respiratory complex I reconstituted into lipid nanodiscs reveals an uncoupled conformation
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    HIV-1 matrix-tRNA complex structure reveals basis for host control of Gag localization
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      DOI: 10.1016/j.chom.2021.07.006

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    sciencedirect.com/science/article/pii/S1931312821003395
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    Protocol for the use of focused ion-beam milling to prepare crystalline lamellae for microcrystal electron diffraction (MicroED)
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  153. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Collection of Continuous Rotation MicroED Data from Ion Beam-Milled Crystals of Any Size
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  154. elifesciences.org elifesciences.org
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    elifesciences.org/articles/16761
  155. elifesciences.org elifesciences.org
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  156. elifesciences.org elifesciences.org
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  157. onlinelibrary.wiley.com onlinelibrary.wiley.com
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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.14631
  158. onlinelibrary.wiley.com onlinelibrary.wiley.com
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  159. www.sciencedirect.com www.sciencedirect.com
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      DOI: 10.1016/j.celrep.2018.11.058

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  160. www.sciencedirect.com www.sciencedirect.com
    A Rare Lysozyme Crystal Form Solved Using Highly Redundant Multiple Electron Diffraction Datasets from Micron-Sized Crystals
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      DOI: 10.1016/j.str.2018.02.015

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    Fcab-HER2 Interaction: a Ménage à Trois. Lessons from X-Ray and Solution Studies
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  163. elifesciences.org elifesciences.org
    Cryo-EM structures of the caspase-activated protein XKR9 involved in apoptotic lipid scrambling
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    Structure and analysis of nanobody binding to the human ASIC1a ion channel
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  165. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structures of translationally inactive mammalian ribosomes
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    Structural basis of protein translocation by the Vps4-Vta1 AAA ATPase
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    Helicase-Dependent RNA Decay Illuminated by a Cryo-EM Structure of a Human Nuclear RNA Exosome-MTR4 Complex
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    High resolution cryo-EM structure of the helical RNA-bound Hantaan virus nucleocapsid reveals its assembly mechanisms
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  174. www.nature.com www.nature.com
    Regulation of the endosomal SNX27-retromer by OTULIN
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    Structure of the thermo-sensitive TRP channel TRP1 from the alga Chlamydomonas reinhardtii
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  176. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Crystal structures of DNA polymerase I capture novel intermediates in the DNA synthesis pathway
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    Structure of the Mechanosensitive Channel MscS Embedded in the Membrane Bilayer
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    Fragment-based discovery of a chemical probe for the PWWP1 domain of NSD3
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    Site-Selective Antibody Functionalization via Orthogonally Reactive Arginine and Lysine Residues
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    Structural and functional characterization of an otopetrin family proton channel
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    Mechanisms for Zinc and Proton Inhibition of the GluN1/GluN2A NMDA Receptor
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    Structural Survey of Broadly Neutralizing Antibodies Targeting the HIV-1 Env Trimer Delineates Epitope Categories and Characteristics of Recognition
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    Neuron-Subtype-Specific Expression, Interaction Affinities, and Specificity Determinants of DIP/Dpr Cell Recognition Proteins
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    Cryo-EM Structures of MDA5-dsRNA Filaments at Different Stages of ATP Hydrolysis
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    Structural Basis for Cholesterol Transport-like Activity of the Hedgehog Receptor Patched
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    A Combination of Two Human Monoclonal Antibodies Prevents Zika Virus Escape Mutations in Non-human Primates
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    Structural Basis of Mitochondrial Transcription Initiation
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  195. Jun 2021
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    Identification of an atypical interaction site in the BTB domain of the MYC-interacting zinc-finger protein 1
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    B cell genomics behind cross-neutralization of SARS-CoV-2 variants and SARS-CoV
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  198. May 2021
  199. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CM1-driven assembly and activation of yeast γ-tubulin small complex underlies microtubule nucleation
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    The Polyglutamine Expansion at the N-Terminal of Huntingtin Protein Modulates the Dynamic Configuration and Phosphorylation of the C-Terminal HEAT Domain
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    Structural Basis for Bacterial Ribosome-Associated Quality Control by RqcH and RqcP
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    Structure-Based Mechanisms of a Molecular RNA Polymerase/Chaperone Machine Required for Ribosome Biosynthesis
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  203. Apr 2021
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    Structural insights into viral RNA capping and plasma membrane targeting by Chikungunya virus nonstructural protein 1
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      DOI: 10.1016/j.chom.2021.02.018

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    sciencedirect.com/science/article/pii/S1931312821000974
  205. www.sciencedirect.com www.sciencedirect.com
    Structural basis for IL-12 and IL-23 receptor sharing reveals a gateway for shaping actions on T versus NK cells
    1
    1. scibot 24 Apr 2021
      RRID:SCR_014224

      DOI: 10.1016/j.cell.2021.01.018

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    sciencedirect.com/science/article/pii/S0092867421000611
  206. www.sciencedirect.com www.sciencedirect.com
    Cellular mRNA triggers structural transformation of Ebola virus matrix protein VP40 to its essential regulatory form
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      RRID:SCR_014224

      DOI: 10.1016/j.celrep.2021.108986

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    sciencedirect.com/science/article/pii/S2211124721003004
  207. www.sciencedirect.com www.sciencedirect.com
    The tissue protective functions of interleukin-22 can be decoupled from pro-inflammatory actions through structure-based design
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    1. scibot 14 Apr 2021
      RRID:SCR_014224

      DOI: 10.1016/j.immuni.2021.03.008

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    sciencedirect.com/science/article/pii/S1074761321001205
  208. www.cell.com www.cell.com
    SARS-CoV-2 evolution in an immunocompromised host reveals shared neutralization escape mechanisms
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      RRID:SCR_014224

      DOI: 10.1016/j.cell.2021.03.027

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    cell.com/cell/fulltext/S0092-8674(21)00355-X
  209. elifesciences.org elifesciences.org
    Architecture and structural dynamics of the heteromeric GluK2/K5 kainate receptor
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    1. scibot 06 Apr 2021
      RRID:SCR_014224

      DOI: 10.7554/eLife.66097

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    elifesciences.org/articles/66097
  210. Mar 2021
  211. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structure and immune recognition of the porcine epidemic diarrhea virus spike protein
    1
    1. scibot 21 Mar 2021
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      DOI: 10.1016/j.str.2020.12.003

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    ncbi.nlm.nih.gov/pmc/articles/PMC7962898/
  212. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Uncovering an allosteric mode of action for a selective inhibitor of human Bloom syndrome protein
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    1. scibot 09 Mar 2021
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      DOI: 10.7554/eLife.65339

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    ncbi.nlm.nih.gov/pmc/articles/PMC7924943/
  213. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitochondrial copper and phosphate transporter specificity was defined early in the evolution of eukaryotes
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    1. scibot 09 Mar 2021
      RRID:SCR_014224

      DOI: 10.7554/eLife.64690

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    ncbi.nlm.nih.gov/pmc/articles/PMC7924939/
  214. www.sciencedirect.com www.sciencedirect.com
    Structural basis for self-cleavage prevention by tag:anti-tag pairing complementarity in type VI Cas13 CRISPR systems
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    1. scibot 01 Mar 2021
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      DOI: 10.1016/j.molcel.2020.12.033

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    sciencedirect.com/science/article/pii/S1097276520309540
  215. www.sciencedirect.com www.sciencedirect.com
    Vaccination induces maturation in a mouse model of diverse unmutated VRC01-class precursors to HIV-neutralizing antibodies with >50% breadth
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    1. scibot 01 Mar 2021
      RRID:SCR_014224

      DOI: 10.1016/j.immuni.2020.12.014

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    sciencedirect.com/science/article/pii/S1074761320305422
  216. Feb 2021
  217. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Atomic structure of a mitochondrial complex I intermediate from vascular plants
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    1. scibot 26 Feb 2021
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      DOI: 10.7554/eLife.56664

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    ncbi.nlm.nih.gov/pmc/articles/PMC7447434/
  218. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structures reveal gatekeeping of the mitochondrial Ca2+ uniporter by MICU1-MICU2
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    1. scibot 26 Feb 2021
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      DOI: 10.7554/eLife.59991

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    ncbi.nlm.nih.gov/pmc/articles/PMC7434445/
  219. www.cell.com www.cell.com
    Calmodulin binds to Drosophila TRP with an unexpected mode
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    1. scibot 26 Feb 2021
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      DOI: 10.1016/j.str.2020.11.016

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    cell.com/structure/abstract/S0969-2126(20)30463-9
  220. elifesciences.org elifesciences.org
    A processive rotary mechanism couples substrate unfolding and proteolysis in the ClpXP degradation machinery
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    1. scibot 25 Feb 2021
      RRID:SCR_014224

      DOI: 10.7554/eLife.52158

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    elifesciences.org/articles/52158
  221. www.cell.com www.cell.com
    Restriction of HIV-1 Escape by a Highly Broad and Potent Neutralizing Antibody
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    1. scibot 24 Feb 2021
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      DOI: 10.1016/j.cell.2020.01.010

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    cell.com/cell/abstract/S0092-8674(20)30057-X
  222. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activation of a nucleotide-dependent RCK domain requires binding of a cation cofactor to a conserved site
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    1. scibot 24 Feb 2021
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      DOI: 10.7554/eLife.50661

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    ncbi.nlm.nih.gov/pmc/articles/PMC6957272/
  223. www.sciencedirect.com www.sciencedirect.com
    Mimicry of Canonical Translation Elongation Underlies Alanine Tail Synthesis in RQC
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      DOI: 10.1016/j.molcel.2020.11.001

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    sciencedirect.com/science/article/pii/S1097276520307796
  224. Jan 2021
  225. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mutations in SKI in Shprintzen–Goldberg syndrome lead to attenuated TGF-β responses through SKI stabilization
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    1. scibot 30 Jan 2021
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      DOI: 10.7554/eLife.63545

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    ncbi.nlm.nih.gov/pmc/articles/PMC7834018/
  226. elifesciences.org elifesciences.org
    Atomic structures of respiratory complex III 2, complex IV, and supercomplex III 2-IV from vascular plants
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    1. scibot 23 Jan 2021
      RRID:SCR_014224

      DOI: 10.7554/eLife.62047

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    elifesciences.org/articles/62047
  227. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structure of bacterial phospholipid transporter MlaFEDB with substrate bound
    1
    1. scibot 13 Jan 2021
      RRID:SCR_014224

      DOI: 10.7554/eLife.62518

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    ncbi.nlm.nih.gov/pmc/articles/PMC7790496/
  228. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural and mechanistic basis of the EMC-dependent biogenesis of distinct transmembrane clients
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    1. scibot 08 Jan 2021
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      DOI: 10.7554/eLife.62611

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    ncbi.nlm.nih.gov/pmc/articles/PMC7785296/
  229. Dec 2020
  230. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structure of the human core transcription-export complex reveals a hub for multivalent interactions
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    1. scibot 25 Dec 2020
      RRID:SCR_014224

      DOI: 10.7554/eLife.61503

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    ncbi.nlm.nih.gov/pmc/articles/PMC7744094/
  231. www.sciencedirect.com www.sciencedirect.com
    Exploitation of Elevated Extracellular ATP to Specifically Direct Antibody to Tumor Microenvironment
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    1. scibot 23 Dec 2020
      SCR_014224

      DOI: 10.1016/j.celrep.2020.108542

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    sciencedirect.com/science/article/pii/S221112472031531X
  232. www.sciencedirect.com www.sciencedirect.com
    The Halastavi árva Virus Intergenic Region IRES Promotes Translation by the Simplest Possible Initiation Mechanism
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    1. scibot 13 Dec 2020
      RRID:SCR_014224

      DOI: 10.1016/j.celrep.2020.108476

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    sciencedirect.com/science/article/pii/S2211124720314650
  233. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cryo-EM structure of the calcium release-activated calcium channel Orai in an open conformation
    1
    1. scibot 12 Dec 2020
      RRID:SCR_014224

      DOI: 10.7554/eLife.62772

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    ncbi.nlm.nih.gov/pmc/articles/PMC7723414/
  234. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural ordering of the Plasmodium berghei circumsporozoite protein repeats by inhibitory antibody 3D11
    1
    1. scibot 09 Dec 2020
      RRID:SCR_014224

      DOI: 10.7554/eLife.59018

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    ncbi.nlm.nih.gov/pmc/articles/PMC7704109/
  235. elifesciences.org elifesciences.org
    The structures of secretory and dimeric immunoglobulin A
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    1. scibot 09 Dec 2020
      RRID:SCR_014224

      DOI: 10.7554/eLife.56098

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    elifesciences.org/articles/56098
  236. www.sciencedirect.com www.sciencedirect.com
    A Strain-Specific Inhibitor of Receptor-Bound HIV-1 Targets a Pocket near the Fusion Peptide
    1
    1. scibot 07 Dec 2020
      RRID:SCR_014224

      DOI: 10.1016/j.celrep.2020.108428

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    sciencedirect.com/science/article/pii/S2211124720314170
  237. Nov 2020
  238. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural basis of ClpXP recognition and unfolding of ssrA-tagged substrates
    1
    1. scibot 18 Nov 2020
      RRID:SCR_014224

      DOI: 10.7554/eLife.61496

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    ncbi.nlm.nih.gov/pmc/articles/PMC7652416/
  239. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural basis of αE-catenin–F-actin catch bond behavior
    1
    1. scibot 13 Nov 2020
      RRID:SCR_014224

      DOI: 10.7554/eLife.60878

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    ncbi.nlm.nih.gov/pmc/articles/PMC7588230/