2,061 Matching Annotations
  1. Jan 2020
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    Fructose-1,6-Bisphosphatase 2 Inhibits Sarcoma Progression by Restraining Mitochondrial Biogenesis
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    sciencedirect.com/science/article/pii/S1550413119305686
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    Induced pluripotent stem cell line (PEIi003-A) derived from an apparently healthy male individual.
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    sciencedirect.com/science/article/pii/S1873506119303095
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    Small-Molecule and CRISPR Screening Converge to Reveal Receptor Tyrosine Kinase Dependencies in Pediatric Rhabdoid Tumors
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    sciencedirect.com/science/article/pii/S2211124719309118
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    SENP1-Sirt3 Signaling Controls Mitochondrial Protein Acetylation and Metabolism
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    A PRMT5-RNF168-SMURF2 Axis Controls H2AX Proteostasis
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    A multimolecular signaling complex including PrPC and LRP1 is strictly dependent on lipid rafts and is essential for the function of tissue Plasminogen Activator
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    Cross-Microbial Protection via Priming a Conserved Immune Co-Receptor through Juxtamembrane Phosphorylation in Plants
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    N-cadherin-regulated FGFR ubiquitination and degradation control mammalian neocortical projection neuron migration
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    Systemic Root-Shoot Signaling Drives Jasmonate-Based Root Defense against Nematodes
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    Structural Basis of Paxillin Recruitment by Kindlin-2 in Regulating Cell Adhesion
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    TLR8 Is a Sensor of RNase T2 Degradation Products
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    Donepezil‐induced oligodendrocyte differentiation is mediated through estrogen receptors
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    The miR-216a-Dot1l Regulatory Axis Is Necessary and Sufficient for Müller Glia Reprogramming during Retina Regeneration
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    Screening the expression of several miRNAs from TaqMan Low Density Array in traumatic brain injury: miR‐219a‐5p regulates neuronal apoptosis by modulating CCNA2 and CACUL1
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    Phosphorylation-mediated interactions with TOPBP1 couple 53BP1 and 9-1-1 to control the G1 DNA damage checkpoint
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      DOI: 10.7554/eLife.44353

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    Oncogene Amplification in Growth Factor Signaling Pathways Renders Cancers Dependent on Membrane Lipid Remodeling
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    Directed RNase H Cleavage of Nascent Transcripts Causes Transcription Termination
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    Amyloid-like Assembly Activates a Phosphatase in the Developing Drosophila Embryo
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    Protective effects of GHK-Cu in bleomycin-induced pulmonary fibrosis via anti-oxidative stress and anti-inflammation pathways
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      DOI: 10.1016/j.lfs.2019.117139

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    Positive Feedback Defines the Timing, Magnitude, and Robustness of Angiogenesis
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    Liver-Type Glutaminase GLS2 Is a Druggable Metabolic Node in Luminal-Subtype Breast Cancer
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    PRDM16 Maintains Homeostasis of the Intestinal Epithelium by Controlling Region-Specific Metabolism
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    Locomotor training with adjuvant testosterone preserves cancellous bone and promotes muscle plasticity in male rats after severe spinal cord injury
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      DOI: 10.1002/jnr.24564

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    Suppression of p16 Induces mTORC1-Mediated Nucleotide Metabolic Reprogramming
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    Modulation of RNA Condensation by the DEAD-Box Protein eIF4A
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    Mitochondrial Damage and Activation of the STING Pathway Lead to Renal Inflammation and Fibrosis
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    Proximity RNA Labeling by APEX-Seq Reveals the Organization of Translation Initiation Complexes and Repressive RNA Granules
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    mTORC1 Activation Requires DRAM-1 by Facilitating Lysosomal Amino Acid Efflux
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    Activin A-induced cachectic wasting is attenuated by systemic delivery of its cognate propeptide in male mice
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      DOI: 10.1210/en.2019-00257

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    Cancer Cells Upregulate NRF2 Signaling to Adapt to Autophagy Inhibition
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    A Menin-MLL Inhibitor Induces Specific Chromatin Changes and Eradicates Disease in Models of MLL-Rearranged Leukemia
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    Fascin Controls Metastatic Colonization and Mitochondrial Oxidative Phosphorylation by Remodeling Mitochondrial Actin Filaments
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    Postmortem Cortex Samples Identify Distinct Molecular Subtypes of ALS: Retrotransposon Activation, Oxidative Stress, and Activated Glia
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    YAP/TAZ Activation Drives Uveal Melanoma Initiation and Progression
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    Glutamate Signaling in Hepatic Stellate Cells Drives Alcoholic Steatosis
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    Inhibition of sirtuin 1 deacetylase by miR-211-5p provides a mechanism for the induction of cell death in breast cancer cells
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    Autoinhibition Mechanism of the Ubiquitin-Conjugating Enzyme UBE2S by Autoubiquitination
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    A Cell-Surface Membrane Protein Signature for Glioblastoma
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    IL-36 promotes anti-viral immunity by boosting sensitivity to IFN-α/β in IRF1 dependent and independent manners
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      DOI: 10.1038/s41467-019-12318-y

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    Semisynthetic biosensors for mapping cellular concentrations of nicotinamide adenine dinucleotides
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    Cyclin A-cdk1-Dependent Phosphorylation of Bora Is the Triggering Factor Promoting Mitotic Entry
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    Phase I Trial: Cirmtuzumab Inhibits ROR1 Signaling and Stemness Signatures in Patients with Chronic Lymphocytic Leukemia
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    The Temporal Dynamics of Arc Expression Regulate Cognitive Flexibility
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    FGF23 Regulates Wnt/β-Catenin Signaling-Mediated Osteoarthritis in Mice Overexpressing High-Molecular-Weight FGF2
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    Unbiased Combinatorial Screening Identifies a Bispecific IgG1 that Potently Inhibits HER3 Signaling via HER2-Guided Ligand Blockade
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    The GABAA Receptor α2 Subunit Activates a Neuronal TLR4 Signal in the Ventral Tegmental Area that Regulates Alcohol and Nicotine Abuse
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    Mitochondrial MDM2 Regulates Respiratory Complex I Activity Independently of p53
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    Helicobacter pylori Infection Modulates Host Cell Metabolism through VacA-Dependent Inhibition of mTORC1
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    PCYT1A Regulates Phosphatidylcholine Homeostasis from the Inner Nuclear Membrane in Response to Membrane Stored Curvature Elastic Stress
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    Design and Profiling of a Subcellular Targeted Optogenetic cAMP-Dependent Protein Kinase
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    Mechanism of Allosteric Coupling into and through the Plasma Membrane by EGFR
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    SOD1 Phosphorylation by mTORC1 Couples Nutrient Sensing and Redox Regulation
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    VEGF signaling regulates the fate of obstructed capillaries in mouse cortex
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    Novel RNA-Affinity Proteogenomics Dissects Tumor Heterogeneity for Revealing Personalized Markers in Precision Prognosis of Cancer
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    Tumor-Repopulating Cells Induce PD-1 Expression in CD8+ T Cells by Transferring Kynurenine and AhR Activation
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    Genome-Scale Signatures of Gene Interaction from Compound Screens Predict Clinical Efficacy of Targeted Cancer Therapies
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    Mitochondria Bound to Lipid Droplets Have Unique Bioenergetics, Composition, and Dynamics that Support Lipid Droplet Expansion
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    Impairing L-Threonine Catabolism Promotes Healthspan through Methylglyoxal-Mediated Proteohormesis
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    Dimerization of the Pragmin Pseudo-Kinase Regulates Protein Tyrosine Phosphorylation
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    Dysregulated IL-18 Is a Key Driver of Immunosuppression and a Possible Therapeutic Target in the Multiple Myeloma Microenvironment
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    Listeria Adhesion Protein Induces Intestinal Epithelial Barrier Dysfunction for Bacterial Translocation
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    Active Protection: Learning-Activated Raf/MAPK Activity Protects Labile Memory from Rac1-Independent Forgetting
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    Bladder-cancer-associated mutations in RXRA activate peroxisome proliferator-activated receptors to drive urothelial proliferation
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    mTOR-dependent alterations of Kv1.1 subunit expression in the neuronal subset-specific Pten knockout mouse model of cortical dysplasia with epilepsy
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      horseradish peroxidase-linked goat anti-rabbit IgG (1:2000, Cell Signaling #7074)

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    Roquin Suppresses the PI3K-mTOR Signaling Pathway to Inhibit T Helper Cell Differentiation and Conversion of Treg to Tfr Cells
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    Direct In Vivo Reprogramming with Sendai Virus Vectors Improves Cardiac Function after Myocardial Infarction
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    Chemical hypoxia‐induced integrated stress response activation in oligodendrocytes is mediated by the transcription factor nuclear factor (erythroid‐derived 2)‐like 2 (NRF2)
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    KRAS Dimerization Impacts MEK Inhibitor Sensitivity and Oncogenic Activity of Mutant KRAS
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    CRISPR/Cas9‒Mediated Tspo Gene Mutations Lead to Reduced Mitochondrial Membrane Potential and Steroid Formation in MA-10 Mouse Tumor Leydig Cells
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