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    PRDX6 dictates ferroptosis sensitivity by directing cellular selenium utilization
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    ARF alters PAF1 complex integrity to selectively repress oncogenic transcription programs upon p53 loss
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    Flow cytometry FRET reveals post-translational modifications drive Protein Phosphatase-5 conformational changes in mammalian cells
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    Bilateral regulation of EGFR activity and local PI(4,5)P2 dynamics in mammalian cells observed with superresolution microscopy
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    Structure of the TXNL1-bound proteasome
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    Distinct effects of sacituzumab govitecan and berzosertib on DNA damage response in ovarian cancer
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    Porcine NLRC3 specially binds short dsDNA to regulate cGAS activation
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    Dental pulp stem cells promote genioglossus repair and systemic amelioration in chronic intermittent hypoxia
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  10. Nov 2024
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    GM1 Oligosaccharide Ameliorates Rett Syndrome Phenotypes In Vitro and In Vivo via Trk Receptor Activation
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    A multivalent adaptor mechanism drives the nuclear import of proteasomes
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    Single-cell sequencing combined with transcriptomics and in vivo and in vitro analysis reveals the landscape of ferroptosis in myocardial ischemia–reperfusion injury
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    SUMOylation of protein phosphatase 5 regulates phosphatase activity and substrate release
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    Nuclear receptor E75/NR1D2 promotes tumor malignant transformation by integrating Hippo and Notch pathways
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    Kaempferol attenuates hyperuricemia combined with gouty arthritis via urate transporters and NLRP3/NF-κB pathway modulation
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    USP7 deubiquitinates KRAS and promotes non-small cell lung cancer
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    Integrated multiomic analysis identifies TRIP13 as a mediator of alveolar epithelial type II cell dysfunction in idiopathic pulmonary fibrosis
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    CRISPRi/a screens in human iPSC-cardiomyocytes identify glycolytic activation as a druggable target for doxorubicin-induced cardiotoxicity
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    Bidirectional signals generated by Siglec-7 and its crucial ligand tri-sialylated T to escape of cancer cells from immune surveillance
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    CircZNF609/miR-324-5p/VDAC1 axis promotes malignant progression of ovarian cancer cells
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    Targeting BCL2 with Venetoclax Enhances the Efficacy of the KRASG12D Inhibitor MRTX1133 in Pancreatic Cancer
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    Sacubitril/Valsartan Combination Partially Improves Cardiac Systolic, but Not Diastolic, Function through β-AR Responsiveness in a Rat Model of Type 2 Diabetes
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    Transgenic sensors reveal compartment-specific effects of aggregation-prone proteins on subcellular proteostasis during aging
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    Multi-omic human pancreatic islet endoplasmic reticulum and cytokine stress response mapping provides type 2 diabetes genetic insights
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    Disruption of cellular plasticity by repeat RNAs in human pancreatic cancer
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    Simple aneuploidy evades p53 surveillance and promotes niche factor-independent growth in human intestinal organoids
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    Maternal stress and the early embryonic microenvironment: investigating long-term cortisol effects on bovine oviductal epithelial cells using air–liquid interface culture
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    PKMYT1 Is a Marker of Treatment Response and a Therapeutic Target for CDK4/6 Inhibitor-Resistance in ER+ Breast Cancer
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    A synonymous mutation of rs1137070 cause the mice Maoa gene transcription and translation to decrease
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    Spatially restricted ecto-5′-nucleotidase expression promotes the growth of uterine leiomyomas by modulating Akt activity
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  39. aacrjournals.org aacrjournals.org
    RAF-Mutant Melanomas Differentially Depend on ERK2 Over ERK1 to Support Aberrant MAPK Pathway Activation and Cell Proliferation
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    Leucine restriction ameliorates Fusobacterium nucleatum-driven malignant progression and radioresistance in nasopharyngeal carcinoma
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    Perfluoropentane-based oxygen-loaded nanodroplets reduce microglial activation through metabolic reprogramming
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  42. Sep 2024
  43. www.biorxiv.org www.biorxiv.org
    Cryo-EM Structure of Phospholipase Cε Defines N-terminal Domains and their Roles in Activity
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