2,113 Matching Annotations
  1. Jun 2021
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tailored generation of insulin producing cells from canine mesenchymal stem cells derived from bone marrow and adipose tissue
    1
    1. scibot 17 Jun 2021
      RRID:Addgene_12259

      DOI: 10.1038/s41598-021-91774-3

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    ncbi.nlm.nih.gov/pmc/articles/PMC8196068/
  3. www.tandfonline.com www.tandfonline.com
    Garcinia cambogia attenuates adipogenesis by affecting CEBPB and SQSTM1/p62-mediated selective autophagic degradation of KLF3 through RPS6KA1 and STAT3 suppression
    1
    1. scibot 17 Jun 2021
      RRID:Addgene_12259

      DOI: 10.1080/15548627.2021.1936356

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    tandfonline.com/doi/full/10.1080/15548627.2021.1936356
  4. www.sciencedirect.com www.sciencedirect.com
    Protocol to establish a lung adenocarcinoma immunotherapy allograft mouse model with FACS and immunofluorescence-based analysis of tumor response
    1
    1. scibot 15 Jun 2021
      Addgene_12259

      DOI: 10.1016/j.xpro.2021.100595

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    sciencedirect.com/science/article/pii/S2666166721003026
  5. www.sciencedirect.com www.sciencedirect.com
    Evaluation of glycolytic rates in human hematopoietic stem/progenitor cells after target gene depletion
    1
    1. scibot 15 Jun 2021
      RRID:Addgene_12259

      DOI: 10.1016/j.xpro.2021.100603

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    sciencedirect.com/science/article/pii/S2666166721003105
  6. www.sciencedirect.com www.sciencedirect.com
    TMBIM1 is an inhibitor of adipogenesis and its depletion promotes adipocyte hyperplasia and improves obesity-related metabolic disease
    1
    1. scibot 12 Jun 2021
      Plasmid #12259

      DOI: 10.1016/j.cmet.2021.05.014

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    sciencedirect.com/science/article/pii/S155041312100231X
  7. www.sciencedirect.com www.sciencedirect.com
    Single-cell lineage tracing of metastatic cancer reveals selection of hybrid EMT states
    1
    1. scibot 12 Jun 2021
      12259

      DOI: 10.1016/j.ccell.2021.05.005

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    sciencedirect.com/science/article/pii/S1535610821002713
  8. elifesciences.org elifesciences.org
    Tight nanoscale clustering of Fcγ receptors using DNA origami promotes phagocytosis
    2
    1. scibot 11 Jun 2021
      plasmid_12259

      DOI: 10.7554/eLife.68311

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    2. scibot 11 Jun 2021
      RRID:addgene_12259

      DOI: 10.7554/eLife.68311

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    elifesciences.org/articles/68311
  9. www.sciencedirect.com www.sciencedirect.com
    DMA-tudor interaction modules control the specificity of in vivo condensates
    1
    1. scibot 11 Jun 2021
      Addgene_12259

      DOI: 10.1016/j.cell.2021.05.008

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    sciencedirect.com/science/article/pii/S0092867421006255
  10. www.sciencedirect.com www.sciencedirect.com
    Reprogramming an energetic AKT-PAK5 axis boosts axon energy supply and facilitates neuron survival and regeneration after injury and ischemia
    1
    1. scibot 04 Jun 2021
      Addgene_12259

      DOI: 10.1016/j.cub.2021.04.079

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    sciencedirect.com/science/article/pii/S0960982221006266
  11. www.nature.com www.nature.com
    Pericentromeric Satellite III transcripts induce etoposide resistance
    1
    1. scibot 02 Jun 2021
      RRID:Addgene_12259

      DOI: 10.1038/s41419-021-03810-9

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    nature.com/articles/s41419-021-03810-9
  12. May 2021
  13. www.sciencedirect.com www.sciencedirect.com
    Peptide-tiling screens of cancer drivers reveal oncogenic protein domains and associated peptide inhibitors
    1
    1. scibot 29 May 2021
      Addgene_12259

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    sciencedirect.com/science/article/pii/S2405471221001575
  14. www.sciencedirect.com www.sciencedirect.com
    Lipolysis drives expression of the constitutively active receptor GPR3 to induce adipose thermogenesis
    1
    1. scibot 28 May 2021
      CAT#12259

      DOI: 10.1016/j.cell.2021.04.037

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    sciencedirect.com/science/article/pii/S0092867421005729
  15. www.sciencedirect.com www.sciencedirect.com
    A phenotypically supervised single-cell analysis protocol to study within-cell-type heterogeneity of cultured mammalian cells
    1
    1. scibot 27 May 2021
      12259

      DOI: 10.1016/j.xpro.2021.100561

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    sciencedirect.com/science/article/pii/S2666166721002689
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SAM homeostasis is regulated by CFIm-mediated splicing of MAT2A
    1
    1. scibot 27 May 2021
      plasmid_12259

      DOI: 10.7554/eLife.64930

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    ncbi.nlm.nih.gov/pmc/articles/PMC8139829/
  17. www.nature.com www.nature.com
    Neuron and astrocyte aggregation and sorting in three-dimensional neuronal constructs
    1
    1. scibot 22 May 2021
      RRID:Addgene_12259

      DOI: 10.1038/s42003-021-02104-2

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    nature.com/articles/s42003-021-02104-2
  18. www.mdpi.com www.mdpi.com
    The Lysine Methylase SMYD3 Modulates Mesendodermal Commitment during Development
    1
    1. scibot 22 May 2021
      RRID:Addgene_12259

      DOI: 10.3390/cells10051233

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    mdpi.com/2073-4409/10/5/1233
  19. www.sciencedirect.com www.sciencedirect.com
    Adhesion-mediated mechanosignaling forces mitohormesis
    1
    1. scibot 21 May 2021
      12259

      DOI: 10.1016/j.cmet.2021.04.017

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    sciencedirect.com/science/article/pii/S1550413121001832
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NOX4 links metabolic regulation in pancreatic cancer to endoplasmic reticulum redox vulnerability and dependence on PRDX4
    1
    1. scibot 19 May 2021
      RRID:Addgene_12259

      DOI: 10.1126/sciadv.abf7114

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    ncbi.nlm.nih.gov/pmc/articles/PMC8104867/
  21. www.sciencedirect.com www.sciencedirect.com
    Cargo receptor-assisted endoplasmic reticulum export of pathogenic α1-antitrypsin polymers
    1
    1. scibot 19 May 2021
      RRID:Addgene_12259

      DOI: 10.1016/j.celrep.2021.109144

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    sciencedirect.com/science/article/pii/S2211124721004836
  22. onlinelibrary.wiley.com onlinelibrary.wiley.com
    In vivo CRISPR screening for novel noncoding RNA functional targets in glioblastoma models
    1
    1. scibot 18 May 2021
      RRID:Addgene_12259

      DOI: 10.1002/jnr.24850

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    onlinelibrary.wiley.com/doi/10.1002/jnr.24850
  23. www.sciencedirect.com www.sciencedirect.com
    CD47 Ligation Repositions the Inhibitory Receptor SIRPA to Suppress Integrin Activation and Phagocytosis
    2
    1. scibot 15 May 2021
      Addgene 12259

      DOI: 10.1016/j.immuni.2020.07.008

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    2. scibot 06 May 2021
      plasmid_12259

      DOI: 10.1016/j.immuni.2020.07.008

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    sciencedirect.com/science/article/pii/S1074761320303150
  24. www.sciencedirect.com www.sciencedirect.com
    Caspase-1 Engages Full-Length Gasdermin D through Two Distinct Interfaces That Mediate Caspase Recruitment and Substrate Cleavage
    1
    1. scibot 15 May 2021
      Cat# 12259

      DOI: 10.1016/j.immuni.2020.06.007

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    sciencedirect.com/science/article/pii/S1074761320302375
  25. www.sciencedirect.com www.sciencedirect.com
    Rab34 GTPase mediates ciliary membrane formation in the intracellular ciliogenesis pathway
    1
    1. scibot 14 May 2021
      RRID: Addgene_12259

      DOI: 10.1016/j.cub.2021.04.075

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    sciencedirect.com/science/article/pii/S0960982221006229
  26. academic.oup.com academic.oup.com
    Minimized combinatorial CRISPR screens identify genetic interactions in autophagy
    1
    1. scibot 12 May 2021
      RRID:Addgene_12259

      DOI: 10.1093/nar/gkab309

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    academic.oup.com/nar/advance-article/doi/10.1093/nar/gkab309/6270805
  27. www.nature.com www.nature.com
    The oncogenic E3 ligase TRIP12 suppresses epithelial–mesenchymal transition (EMT) and mesenchymal traits through ZEB1/2
    1
    1. scibot 12 May 2021
      RRID:Addgene_12259

      DOI: 10.1038/s41420-021-00479-z

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    nature.com/articles/s41420-021-00479-z
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Assessing the Association of Mitochondrial Function and Inflammasome Activation in Murine Macrophages Exposed to Select Mitotoxic Tri-Organotin Compounds
    1
    1. scibot 12 May 2021
      RRID:Addgene_12259

      DOI: 10.1289/EHP8314

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    ncbi.nlm.nih.gov/pmc/articles/PMC8086801/
  29. www.sciencedirect.com www.sciencedirect.com
    Targeting SUMOylation dependency in human cancer stem cells through a unique SAE2 motif revealed by chemical genomics
    1
    1. scibot 12 May 2021
      Addgene_12259

      DOI: 10.1016/j.chembiol.2021.04.014

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    sciencedirect.com/science/article/pii/S2451945621002075
  30. www.sciencedirect.com www.sciencedirect.com
    p53 mediates target gene association with nuclear speckles for amplified RNA expression
    1
    1. scibot 11 May 2021
      RRID:Addgene_12259

      DOI: 10.1016/j.molcel.2021.03.006

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    sciencedirect.com/science/article/pii/S109727652100174X
  31. www.sciencedirect.com www.sciencedirect.com
    Systematic Functional Analysis of SARS-CoV-2 Proteins Uncovers Viral Innate Immune Antagonists and Remaining Vulnerabilities
    1
    1. scibot 11 May 2021
      RRID:Addgene_12259

      DOI: 10.1016/j.celrep.2021.109126

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    sciencedirect.com/science/article/pii/S2211124721004654
  32. www.eneuro.org www.eneuro.org
    FEZ1 forms complexes with CRMP1 and DCC to regulate axon and dendrite development
    1
    1. scibot 10 May 2021
      RRID:Addgene_12259

      DOI: 10.1523/ENEURO.0193-20.2021

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    eneuro.org/content/8/2/ENEURO.0193-20.2021
  33. www.nature.com www.nature.com
    Multiple interactions of the oncoprotein transcription factor MYC with the SWI/SNF chromatin remodeler
    1
    1. scibot 10 May 2021
      RRID:Addgene_12259

      DOI: 10.1038/s41388-021-01804-7

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    nature.com/articles/s41388-021-01804-7
  34. portlandpress.com portlandpress.com
    Calcitriol increases frataxin levels and restores mitochondrial function in cell models of Friedreich Ataxia
    1
    1. scibot 09 May 2021
      RRID:Addgene_12259

      DOI: 10.1042/BCJ20200331

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    portlandpress.com/biochemj/article/478/1/1/227164/Calcitriol-increases-frataxin-levels-and-restores
  35. www.sciencedirect.com www.sciencedirect.com
    Selective Translation of Cell Fate Regulators Mediates Tolerance to Broad Oncogenic Stress
    1
    1. scibot 09 May 2021
      RRID:Addgene_12259

      DOI: 10.1016/j.stem.2020.05.007

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    sciencedirect.com/science/article/pii/S1934590920302058
  36. www.sciencedirect.com www.sciencedirect.com
    The Rational Development of CD133-Targeting Immunotherapies for Glioblastoma
    1
    1. scibot 08 May 2021
      RRID:Addgene_12259

      DOI: 10.1016/j.stem.2020.04.008

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    sciencedirect.com/science/article/pii/S1934590920301478
  37. www.sciencedirect.com www.sciencedirect.com
    Amino Acids Enhance Polyubiquitination of Rheb and Its Binding to mTORC1 by Blocking Lysosomal ATXN3 Deubiquitinase Activity
    1
    1. scibot 07 May 2021
      plasmid_12259

      DOI: 10.1016/j.molcel.2020.10.004

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    sciencedirect.com/science/article/pii/S1097276520306870
  38. www.sciencedirect.com www.sciencedirect.com
    Proteasome-Bound UCH37/UCHL5 Debranches Ubiquitin Chains to Promote Degradation
    1
    1. scibot 07 May 2021
      Plasmid_12259

      DOI: 10.1016/j.molcel.2020.10.017

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    sciencedirect.com/science/article/pii/S1097276520307243
  39. www.sciencedirect.com www.sciencedirect.com
    RNF126-Mediated Reubiquitination Is Required for Proteasomal Degradation of p97-Extracted Membrane Proteins
    1
    1. scibot 07 May 2021
      Addgene_12259

      DOI: 10.1016/j.molcel.2020.06.023

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    sciencedirect.com/science/article/pii/S1097276520304251
  40. www.sciencedirect.com www.sciencedirect.com
    HLTF Promotes Fork Reversal, Limiting Replication Stress Resistance and Preventing Multiple Mechanisms of Unrestrained DNA Synthesis
    1
    1. scibot 07 May 2021
      RRID:Addgene_12259

      DOI: 10.1016/j.molcel.2020.04.031

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    sciencedirect.com/science/article/pii/S1097276520302732
  41. www.sciencedirect.com www.sciencedirect.com
    Targeted delivery of siRNAs against hepatocellular carcinoma-related genes by a galactosylated polyaspartamide copolymer
    1
    1. scibot 07 May 2021
      plasmid_12259

      DOI: 10.1016/j.jconrel.2020.11.020

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    sciencedirect.com/science/article/pii/S0168365920306696
  42. www.sciencedirect.com www.sciencedirect.com
    Genome-wide Screens Identify Lineage- and Tumor-Specific Genes Modulating MHC-I- and MHC-II-Restricted Immunosurveillance of Human Lymphomas
    1
    1. scibot 07 May 2021
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      DOI: 10.1016/j.immuni.2020.11.002

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    sciencedirect.com/science/article/pii/S1074761320304672
  43. www.sciencedirect.com www.sciencedirect.com
    Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains
    1
    1. scibot 06 May 2021
      Addgene_12259

      DOI: 10.1016/j.molcel.2021.04.012

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    sciencedirect.com/science/article/pii/S1097276521003178
  44. www.sciencedirect.com www.sciencedirect.com
    A Single-Cell Transcriptomic Atlas of Human Skin Aging
    1
    1. scibot 05 May 2021
      plasmid_12259

      DOI: 10.1016/j.devcel.2020.11.002

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  45. www.sciencedirect.com www.sciencedirect.com
    Mechanical Tension Promotes Formation of Gastrulation-like Nodes and Patterns Mesoderm Specification in Human Embryonic Stem Cells
    1
    1. scibot 05 May 2021
      RRID:Addgene_12259

      DOI: 10.1016/j.devcel.2020.10.015

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    sciencedirect.com/science/article/pii/S1534580720308352
  46. www.sciencedirect.com www.sciencedirect.com
    A Membrane-Tethered Ubiquitination Pathway Regulates Hedgehog Signaling and Heart Development
    1
    1. scibot 05 May 2021
      Addgene_12259

      DOI: 10.1016/j.devcel.2020.08.012

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    sciencedirect.com/science/article/pii/S1534580720306705
  47. www.sciencedirect.com www.sciencedirect.com
    An Excitable Ras/PI3K/ERK Signaling Network Controls Migration and Oncogenic Transformation in Epithelial Cells
    1
    1. scibot 05 May 2021
      Plasmid_12259

      DOI: 10.1016/j.devcel.2020.08.001

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    sciencedirect.com/science/article/pii/S1534580720305992
  48. www.sciencedirect.com www.sciencedirect.com
    Mitotic ER Exit Site Disassembly and Reassembly Are Regulated by the Phosphorylation Status of TANGO1
    1
    1. scibot 05 May 2021
      RRID:Addgene_12259

      DOI: 10.1016/j.devcel.2020.07.017

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    sciencedirect.com/science/article/pii/S153458072030592X
  49. www.sciencedirect.com www.sciencedirect.com
    Activation of HERV-K(HML-2) disrupts cortical patterning and neuronal differentiation by increasing NTRK3
    1
    1. scibot 05 May 2021
      plasmid_12259

      DOI: 10.1016/j.stem.2021.04.009

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    sciencedirect.com/science/article/pii/S1934590921001661
  50. www.sciencedirect.com www.sciencedirect.com
    Direct visualization of epithelial microvilli biogenesis
    1
    1. scibot 05 May 2021
      Addgene_12259

      DOI: 10.1016/j.cub.2021.04.012

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    sciencedirect.com/science/article/pii/S096098222100525X
  51. www.sciencedirect.com www.sciencedirect.com
    Ligand Binding to the Collagen VI Receptor Triggers a Talin-to-RhoA Switch that Regulates Receptor Endocytosis
    1
    1. scibot 04 May 2021
      12259

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    sciencedirect.com/science/article/pii/S1534580720303178
  52. www.sciencedirect.com www.sciencedirect.com
    Targeting microRNA-mediated gene repression limits adipogenic conversion of skeletal muscle mesenchymal stromal cells
    1
    1. scibot 04 May 2021
      Addgene_12259

      DOI: 10.1016/j.stem.2021.04.008

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    sciencedirect.com/science/article/pii/S193459092100165X
  53. www.sciencedirect.com www.sciencedirect.com
    Transient Primary Cilia Mediate Robust Hedgehog Pathway-Dependent Cell Cycle Control
    1
    1. scibot 01 May 2021
      RRID:Addgene_12259

      DOI: 10.1016/j.cub.2020.05.004

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    sciencedirect.com/science/article/pii/S0960982220306436
  54. Apr 2021
  55. www.sciencedirect.com www.sciencedirect.com
    Tumor Reliance on Cytosolic versus Mitochondrial One-Carbon Flux Depends on Folate Availability
    1
    1. scibot 30 Apr 2021
      Cat#: 12259

      DOI: 10.1016/j.cmet.2020.12.002

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    sciencedirect.com/science/article/pii/S1550413120306574
  56. www.sciencedirect.com www.sciencedirect.com
    Local Mitochondrial ATP Production Regulates Endothelial Fatty Acid Uptake and Transport
    2
    1. scibot 29 Apr 2021
      Cat#12259

      DOI: 10.1016/j.cmet.2020.05.018

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      RRIDCUR:Missing RRID:Addgene_12259
    2. scibot 29 Apr 2021
      addgene_12259

      DOI: 10.1016/j.cmet.2020.05.018

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    sciencedirect.com/science/article/pii/S1550413120302576
  57. www.sciencedirect.com www.sciencedirect.com
    Discovery of cellular substrates of human RNA-decapping enzyme DCP2 using a stapled bicyclic peptide inhibitor
    1
    1. scibot 28 Apr 2021
      Addgene Cat#12259

      DOI: 10.1016/j.chembiol.2020.12.003

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    sciencedirect.com/science/article/pii/S2451945620304785
  58. www.sciencedirect.com www.sciencedirect.com
    Transcriptional control of DNA repair networks by CDK7 regulates sensitivity to radiation in MYC-driven medulloblastoma
    1
    1. scibot 28 Apr 2021
      Cat#12259

      DOI: 10.1016/j.celrep.2021.109013

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    sciencedirect.com/science/article/pii/S2211124721003272
  59. www.sciencedirect.com www.sciencedirect.com
    Inhibition of mitochondrial translation suppresses glioblastoma stem cell growth
    1
    1. scibot 28 Apr 2021
      RRID:Addgene_12259

      DOI: 10.1016/j.celrep.2021.109024

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    sciencedirect.com/science/article/pii/S2211124721003387
  60. www.sciencedirect.com www.sciencedirect.com
    Colonic epithelial adaptation to EGFR-independent growth induces chromosomal instability and is accelerated by prior injury
    1
    1. scibot 27 Apr 2021
      Addgene plasmid RRID# 12259

      DOI: 10.1016/j.neo.2021.03.010

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    sciencedirect.com/science/article/pii/S1476558621000208
  61. www.sciencedirect.com www.sciencedirect.com
    A Method for Conditional Regulation of Protein Stability in Native or Near-Native Form
    1
    1. scibot 27 Apr 2021
      Plasmid_12259

      DOI: 10.1016/j.chembiol.2020.09.004

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    sciencedirect.com/science/article/pii/S2451945620303767
  62. www.sciencedirect.com www.sciencedirect.com
    Illuminating Host-Mycobacterial Interactions with Genome-wide CRISPR Knockout and CRISPRi Screens
    1
    1. scibot 27 Apr 2021
      Addgene_12259

      DOI: 10.1016/j.cels.2020.08.010

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    sciencedirect.com/science/article/pii/S2405471220302945
  63. www.sciencedirect.com www.sciencedirect.com
    Genetically engineered myeloid cells rebalance the core immune suppression program in metastasis
    1
    1. scibot 27 Apr 2021
      RRID:Addgene_12259

      DOI: 10.1016/j.cell.2021.02.048

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    sciencedirect.com/science/article/pii/S0092867421002373
  64. www.sciencedirect.com www.sciencedirect.com
    A Structural Model of the Endogenous Human BAF Complex Informs Disease Mechanisms
    1
    1. scibot 24 Apr 2021
      RRID: Addgene_12259

      DOI: 10.1016/j.cell.2020.09.051

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    sciencedirect.com/science/article/pii/S0092867420312484
  65. www.sciencedirect.com www.sciencedirect.com
    CD81 Controls Beige Fat Progenitor Cell Growth and Energy Balance via FAK Signaling
    1
    1. scibot 24 Apr 2021
      Cat# 12259

      DOI: 10.1016/j.cell.2020.06.021

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    sciencedirect.com/science/article/pii/S0092867420307534
  66. www.sciencedirect.com www.sciencedirect.com
    p53 is a central regulator driving neurodegeneration caused by C9orf72 poly(PR)
    1
    1. scibot 24 Apr 2021
      Addgene 12259

      DOI: 10.1016/j.cell.2020.12.025

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    sciencedirect.com/science/article/pii/S0092867420317475
  67. www.sciencedirect.com www.sciencedirect.com
    High-Throughput Discovery and Characterization of Human Transcriptional Effectors
    1
    1. scibot 24 Apr 2021
      RRID:Addgene_12259

      DOI: 10.1016/j.cell.2020.11.024

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    sciencedirect.com/science/article/pii/S0092867420315415
  68. www.sciencedirect.com www.sciencedirect.com
    Defining the Teratoma as a Model for Multi-lineage Human Development
    1
    1. scibot 24 Apr 2021
      Addgene_12259

      DOI: 10.1016/j.cell.2020.10.018

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    sciencedirect.com/science/article/pii/S0092867420313817
  69. www.sciencedirect.com www.sciencedirect.com
    Neurons Release Serine to Support mRNA Translation in Pancreatic Cancer
    1
    1. scibot 24 Apr 2021
      Addgene_12259

      DOI: 10.1016/j.cell.2020.10.016

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    sciencedirect.com/science/article/pii/S0092867420313222
  70. www.sciencedirect.com www.sciencedirect.com
    Self-Reporting Transposons Enable Simultaneous Readout of Gene Expression and Transcription Factor Binding in Single Cells
    1
    1. scibot 24 Apr 2021
      plasmid_12259

      DOI: 10.1016/j.cell.2020.06.037

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    sciencedirect.com/science/article/pii/S009286742030814X
  71. www.sciencedirect.com www.sciencedirect.com
    Type V Collagen in Scar Tissue Regulates the Size of Scar after Heart Injury
    1
    1. scibot 24 Apr 2021
      Addgene_12259

      DOI: 10.1016/j.cell.2020.06.030

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    sciencedirect.com/science/article/pii/S0092867420308072
  72. www.sciencedirect.com www.sciencedirect.com
    A Genetic Map of the Response to DNA Damage in Human Cells
    2
    1. scibot 23 Apr 2021
      Addgene Cat# 12259

      DOI: 10.1016/j.cell.2020.05.040

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      Addgene_12259

      DOI: 10.1016/j.cell.2020.05.040

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    sciencedirect.com/science/article/pii/S0092867420306735
  73. www.sciencedirect.com www.sciencedirect.com
    Cancer Burden Is Controlled by Mural Cell-β3-Integrin Regulated Crosstalk with Tumor Cells
    1
    1. scibot 23 Apr 2021
      CAT#12259

      DOI: 10.1016/j.cell.2020.02.003

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    sciencedirect.com/science/article/pii/S0092867420301471
  74. www.sciencedirect.com www.sciencedirect.com
    MDMX acts as a pervasive preleukemic-to-acute myeloid leukemia transition mechanism
    1
    1. scibot 22 Apr 2021
      12259

      DOI: 10.1016/j.ccell.2021.02.006

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    sciencedirect.com/science/article/pii/S1535610821001082
  75. www.sciencedirect.com www.sciencedirect.com
    YTHDF3 Induces the Translation of m6A-Enriched Gene Transcripts to Promote Breast Cancer Brain Metastasis
    1
    1. scibot 22 Apr 2021
      Cat# 12259

      DOI: 10.1016/j.ccell.2020.10.004

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    sciencedirect.com/science/article/pii/S1535610820304980
  76. www.sciencedirect.com www.sciencedirect.com
    Cholesterol Pathway Inhibition Induces TGF-β Signaling to Promote Basal Differentiation in Pancreatic Cancer
    1
    1. scibot 22 Apr 2021
      plasmid_12259

      DOI: 10.1016/j.ccell.2020.08.015

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    sciencedirect.com/science/article/pii/S1535610820304268
  77. www.sciencedirect.com www.sciencedirect.com
    The bone microenvironment increases phenotypic plasticity of ER+ breast cancer cells
    2
    1. scibot 20 Apr 2021
      RRID:_Addgene_12259

      DOI: 10.1016/j.devcel.2021.03.008

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      RRIDCUR:Unresolved RRID:Addgene_12259 RRIDCUR:SyntaxError
    2. scibot 20 Apr 2021
      Plasmid_12259

      DOI: 10.1016/j.devcel.2021.03.008

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    sciencedirect.com/science/article/pii/S1534580721002057
  78. www.sciencedirect.com www.sciencedirect.com
    Lipid-mediated motor-adaptor sequestration impairs axonal lysosome delivery leading to autophagic stress and dystrophy in Niemann-Pick type C
    1
    1. scibot 20 Apr 2021
      plasmid_12259

      DOI: 10.1016/j.devcel.2021.03.032

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    sciencedirect.com/science/article/pii/S1534580721003075
  79. www.sciencedirect.com www.sciencedirect.com
    Selective Inhibition of STRN3-Containing PP2A Phosphatase Restores Hippo Tumor-Suppressor Activity in Gastric Cancer
    1
    1. scibot 17 Apr 2021
      Cat# 12259

      DOI: 10.1016/j.ccell.2020.05.019

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    sciencedirect.com/science/article/pii/S1535610820302695
  80. www.sciencedirect.com www.sciencedirect.com
    MAX Functions as a Tumor Suppressor and Rewires Metabolism in Small Cell Lung Cancer
    1
    1. scibot 17 Apr 2021
      Cat# 12259

      DOI: 10.1016/j.ccell.2020.04.016

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    sciencedirect.com/science/article/pii/S1535610820302154
  81. www.sciencedirect.com www.sciencedirect.com
    Targeting FTO Suppresses Cancer Stem Cell Maintenance and Immune Evasion
    1
    1. scibot 17 Apr 2021
      RRID:Addgene_12259

      DOI: 10.1016/j.ccell.2020.04.017

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    sciencedirect.com/science/article/pii/S1535610820302166
  82. www.sciencedirect.com www.sciencedirect.com
    SETD5-Coordinated Chromatin Reprogramming Regulates Adaptive Resistance to Targeted Pancreatic Cancer Therapy
    1
    1. scibot 17 Apr 2021
      Addgene_12259

      DOI: 10.1016/j.ccell.2020.04.014

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    sciencedirect.com/science/article/pii/S1535610820302130
  83. www.sciencedirect.com www.sciencedirect.com
    Integrative protocols for an in vitro generation of pancreatic progenitors from human dental pulp stem cells
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    1. scibot 16 Apr 2021
      RRID:Addgene_12259

      DOI: 10.1016/j.bbrc.2020.06.145

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    sciencedirect.com/science/article/pii/S0006291X20313644
  84. www.sciencedirect.com www.sciencedirect.com
    A membrane arm of mitochondrial complex I sufficient to promote respirasome formation
    1
    1. scibot 15 Apr 2021
      RRID:Addgene_12259

      DOI: 10.1016/j.celrep.2021.108963

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    sciencedirect.com/science/article/pii/S2211124721002771
  85. www.sciencedirect.com www.sciencedirect.com
    Golgi apparatus-synthesized sulfated glycosaminoglycans mediate polymerization and activation of the cGAMP sensor STING
    1
    1. scibot 15 Apr 2021
      RRID:Addgene_12259

      DOI: 10.1016/j.immuni.2021.03.011

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    sciencedirect.com/science/article/pii/S1074761321001230
  86. www.sciencedirect.com www.sciencedirect.com
    Huntingtin-mediated axonal transport requires arginine methylation by PRMT6
    1
    1. scibot 14 Apr 2021
      Addgene #12259

      DOI: 10.1016/j.celrep.2021.108980

      Resource: RRID:Addgene_12259

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    sciencedirect.com/science/article/pii/S2211124721002941
  87. www.cell.com www.cell.com
    Loss of LUC7L2 and U1 snRNP subunits shifts energy metabolism from glycolysis to OXPHOS
    1
    1. scibot 14 Apr 2021
      Plasmid_12259

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    cell.com/molecular-cell/fulltext/S1097-2765(21)00143-X
  88. www.sciencedirect.com www.sciencedirect.com
    In vivo CRISPR screening reveals nutrient signaling processes underpinning CD8+ T cell fate decisions
    1
    1. scibot 11 Apr 2021
      plasmid # 12259

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    sciencedirect.com/science/article/pii/S0092867421001719
  89. www.sciencedirect.com www.sciencedirect.com
    Pooled CRISPR-activation screening coupled with single-cell RNA-seq in mouse embryonic stem cells
    1
    1. scibot 10 Apr 2021
      plasmid_12259

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    sciencedirect.com/science/article/pii/S2666166721001337
  90. www.sciencedirect.com www.sciencedirect.com
    Creatine promotes cancer metastasis through activation of Smad2/3
    1
    1. scibot 06 Apr 2021
      pMD2.G

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    sciencedirect.com/science/article/pii/S1550413121001169
  91. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The mTORC1-mediated activation of ATF4 promotes protein and glutathione synthesis downstream of growth signals
    1
    1. scibot 06 Apr 2021
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    ncbi.nlm.nih.gov/pmc/articles/PMC7997658/
  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Intraductal transplantation models of human pancreatic ductal adenocarcinoma reveal progressive transition of molecular subtypes
    1
    1. scibot 02 Apr 2021
      Addgene_12259

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    ncbi.nlm.nih.gov/pmc/articles/PMC7664990/
  93. Mar 2021
  94. www.sciencedirect.com www.sciencedirect.com
    Systematic characterization of mutations altering protein degradation in human cancers
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    1. scibot 29 Mar 2021
      RRID:Addgene_12259

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    sciencedirect.com/science/article/pii/S109727652100040X
  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Plxdc family members are novel receptors for the rhesus monkey rhadinovirus (RRV)
    1
    1. scibot 28 Mar 2021
      plasmid_12259

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    ncbi.nlm.nih.gov/pmc/articles/PMC7959344/
  96. www.sciencedirect.com www.sciencedirect.com
    Gasdermin D mediates the maturation and release of IL-1α downstream of inflammasomes
    1
    1. scibot 24 Mar 2021
      Addgene_12259

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    sciencedirect.com/science/article/pii/S2211124721002011
  97. www.sciencedirect.com www.sciencedirect.com
    On the role of p53 in the cellular response to aneuploidy
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    1. scibot 24 Mar 2021
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    sciencedirect.com/science/article/pii/S2211124721002060
  98. www.sciencedirect.com www.sciencedirect.com
    H3.3-K27M drives neural stem cell-specific gliomagenesis in a human iPSC-derived model
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      RRID:Addgene_12259

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    sciencedirect.com/science/article/pii/S1535610821000490
  99. www.sciencedirect.com www.sciencedirect.com
    Quantitative and Dynamic Catalogs of Proteins Released during Apoptotic and Necroptotic Cell Death
    1
    1. scibot 18 Mar 2021
      Addgene_122259

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    sciencedirect.com/science/article/pii/S2211124719317449
  100. www.sciencedirect.com www.sciencedirect.com
    Parkin is an E3 ligase for the ubiquitin-like modifier FAT10, which inhibits Parkin activation and mitophagy
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      plasmid_12259

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    sciencedirect.com/science/article/pii/S2211124721001716
  101. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SFPQ regulates the accumulation of RNA foci and dipeptide repeat proteins from the expanded repeat mutation in C9orf72
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      RRID:Addgene_12259

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    ncbi.nlm.nih.gov/pmc/articles/PMC7904093/
  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape
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      plasmid_12259

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    ncbi.nlm.nih.gov/pmc/articles/PMC7932109/
  103. www.sciencedirect.com www.sciencedirect.com
    Functional cooperation between co-amplified genes promotes aggressive phenotypes of HER2-positive breast cancer
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    1. scibot 11 Mar 2021
      Addgene Cat # 12259

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    sciencedirect.com/science/article/pii/S2211124721001364
  104. www.sciencedirect.com www.sciencedirect.com
    Phosphorylation state of the histone variant H2A.X controls human stem and progenitor cell fate decisions
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      Addgene Cat# 12259

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    sciencedirect.com/science/article/pii/S2211124721001327
  105. actaneurocomms.biomedcentral.com actaneurocomms.biomedcentral.com
    C11orf95-RELA fusion drives aberrant gene expression through the unique epigenetic regulation for ependymoma formation
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      RRID:Addgene_12259

      DOI: 10.1186/s40478-021-01135-4

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    actaneurocomms.biomedcentral.com/article/10.1186/s40478-021-01135-4
  106. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cholesterol alters mitophagy by impairing optineurin recruitment and lysosomal clearance in Alzheimer’s disease
    1
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      RRID:Addgene_12259

      DOI: 10.1186/s13024-021-00435-6

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    ncbi.nlm.nih.gov/pmc/articles/PMC7941983/
  107. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comprehensive Analysis of CD4+ T Cell Responses to CMV pp65 Antigen Restricted by Single HLA-DR, -DQ, and -DP Allotype Within an Individual
    1
    1. scibot 04 Mar 2021
      RRID : Addgene_12259

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    ncbi.nlm.nih.gov/pmc/articles/PMC7917246/
  108. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Ubiquitination and the Proteasome rather than Caspase‐3‐Mediated C‐Terminal Cleavage are Involved in the EAAT2 Degradation by Staurosporine‐Induced Cellular Stress
    1
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      RRID:Addgene_12259

      DOI: 10.1111/jnc.15237

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    onlinelibrary.wiley.com/doi/10.1111/jnc.15237
  109. www.sciencedirect.com www.sciencedirect.com
    Oncogenic translation directs spliceosome dynamics revealing an integral role for SF3A3 in breast cancer
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      Addgene_12259

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    sciencedirect.com/science/article/pii/S109727652100054X
  110. www.frontiersin.org www.frontiersin.org
    Novel Secreted Protein of Mycoplasma bovis MbovP280 Induces Macrophage Apoptosis Through CRYAB
    1
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      RRID:Addgene_12259

      DOI: 10.3389/fimmu.2021.619362

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    frontiersin.org/article/10.3389/fimmu.2021.619362/full
  111. www.sciencedirect.com www.sciencedirect.com
    Post-transcriptional regulation of antiviral gene expression by N6-methyladenosine
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    1. scibot 03 Mar 2021
      RRID:Addgene_12259

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    sciencedirect.com/science/article/pii/S2211124721001121
  112. www.sciencedirect.com www.sciencedirect.com
    A FLCN-TFE3 Feedback Loop Prevents Excessive Glycogenesis and Phagocyte Activation by Regulating Lysosome Activity
    1
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      Plasmid_12259

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    sciencedirect.com/science/article/pii/S2211124720300668
  113. www.jbc.org www.jbc.org
    A conserved acetylation switch enables pharmacological control of tubby-like protein stability
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      RRID:Addgene_12259

      DOI: 10.1074/jbc.RA120.015839

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    jbc.org/article/S0021-9258(20)00061-7/abstract
  114. www.sciencedirect.com www.sciencedirect.com
    ER-directed TREX1 limits cGAS activation at micronuclei
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    sciencedirect.com/science/article/pii/S1097276520309588
  115. Feb 2021
  116. www.sciencedirect.com www.sciencedirect.com
    R-2-hydroxyglutarate attenuates aerobic glycolysis in leukemia by targeting the FTO/m6A/PFKP/LDHB axis
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    1. scibot 28 Feb 2021
      RRID:Addgene_12259

      DOI: 10.1016/j.molcel.2020.12.026

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    sciencedirect.com/science/article/pii/S1097276520309473
  117. www.sciencedirect.com www.sciencedirect.com
    A modular master regulator landscape controls cancer transcriptional identity
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      DOI: 10.1016/j.cell.2020.11.045

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    sciencedirect.com/science/article/pii/S0092867420316172
  118. www.sciencedirect.com www.sciencedirect.com
    The TGF-β superfamily cytokine Activin-A is induced during autoimmune neuroinflammation and drives pathogenic Th17 cell differentiation
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    1. scibot 28 Feb 2021
      RRID:Addgene_12259

      DOI: 10.1016/j.immuni.2020.12.010

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    sciencedirect.com/science/article/pii/S1074761320305380
  119. www.sciencedirect.com www.sciencedirect.com
    microRNA-induced translational control of antiviral immunity by the cap-binding protein 4EHP
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    1. scibot 28 Feb 2021
      RRID:Addgene_12259

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    sciencedirect.com/science/article/pii/S1097276521000502
  120. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of SARS-CoV-2 viral entry upon blocking N- and O-glycan elaboration
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    1. scibot 27 Feb 2021
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      DOI: 10.7554/eLife.61552

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    ncbi.nlm.nih.gov/pmc/articles/PMC7685702/
  121. onlinelibrary.wiley.com onlinelibrary.wiley.com
    NRASQ61K melanoma tumor formation is reduced by p38‐MAPK14 activation in zebrafish models and NRAS‐mutated human melanoma cells
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      DOI: 10.1111/pcmr.12925

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    onlinelibrary.wiley.com/doi/10.1111/pcmr.12925
  122. www.sciencedirect.com www.sciencedirect.com
    Endolysosomal Targeting of Mitochondria Is Integral to BAX-Mediated Mitochondrial Permeabilization during Apoptosis Signaling
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      RRID:Addgene_12259

      DOI: 10.1016/j.devcel.2020.05.014

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    sciencedirect.com/science/article/pii/S1534580720304032
  123. pubs.acs.org pubs.acs.org
    Proximal Biotinylation Based Combinatory Approach for Isolating Integral Plasma Membrane Proteins
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      RRID:Addgene_12259

      DOI: 10.1021/acs.jproteome.0c00113

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    pubs.acs.org/doi/full/10.1021/acs.jproteome.0c00113
  124. pubs.acs.org pubs.acs.org
    Cell-Based Ligand Discovery for the ENL YEATS Domain
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      RRID:Addgene_12259

      DOI: 10.1021/acschembio.0c00124

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    pubs.acs.org/doi/full/10.1021/acschembio.0c00124
  125. pubs.acs.org pubs.acs.org
    Multivalent Peptide-functionalized Bioreducible Polymers for Cellular Delivery of Various RNAs
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      RRID:Addgene_12259

      DOI: 10.1021/acs.biomac.0c00211

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    pubs.acs.org/doi/full/10.1021/acs.biomac.0c00211
  126. www.sciencedirect.com www.sciencedirect.com
    Targeting EphA2 suppresses hepatocellular carcinoma initiation and progression by dual inhibition of JAK1/STAT3 and AKT signaling
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      DOI: 10.1016/j.celrep.2021.108765

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    sciencedirect.com/science/article/pii/S2211124721000784
  127. www.sciencedirect.com www.sciencedirect.com
    The corepressors GPS2 and SMRT control enhancer and silencer remodeling via eRNA transcription during inflammatory activation of macrophages
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    1. scibot 24 Feb 2021
      12259

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    sciencedirect.com/science/article/pii/S1097276520309618
  128. www.nature.com www.nature.com
    On-chip 3D neuromuscular model for drug screening and precision medicine in neuromuscular disease
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      DOI: 10.1038/s41596-019-0248-1

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    nature.com/articles/s41596-019-0248-1
  129. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Efficient and Robust NK-Cell Transduction With Baboon Envelope Pseudotyped Lentivector
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      DOI: 10.3389/fimmu.2019.02873

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    ncbi.nlm.nih.gov/pmc/articles/PMC6927467/
  130. www.sciencedirect.com www.sciencedirect.com
    Development of a peptide-based delivery platform for targeting malignant brain tumors
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      RRID:Addgene_12

      DOI: 10.1016/j.biomaterials.2020.120105

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    sciencedirect.com/science/article/pii/S0142961220303513
  131. link.springer.com link.springer.com
    Impaired differentiation of human induced neural stem cells by TOR1A overexpression
    1
    1. scibot 24 Feb 2021
      plasmid_12

      DOI: 10.1007/s11033-020-05390-x

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    link.springer.com/article/10.1007/s11033-020-05390-x
  132. www.sciencedirect.com www.sciencedirect.com
    Epigenetic Silencing of CDR1as Drives IGF2BP3-Mediated Melanoma Invasion and Metastasis
    1
    1. scibot 24 Feb 2021
      RRID:_Addgene_12259

      DOI: 10.1016/j.ccell.2019.12.007

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    sciencedirect.com/science/article/pii/S153561081930577X
  133. www.cell.com www.cell.com
    TMEM41B IS A PAN-FLAVIVIRUS HOST FACTOR
    1
    1. scibot 24 Feb 2021
      RRID:Addgene_12259

      DOI: 10.1016/j.cell.2020.12.005

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    cell.com/cell/abstract/S0092-8674(20)31627-5
  134. www.cell.com www.cell.com
    Immunogenic Chemotherapy Enhances Recruitment of CAR-T Cells to Lung Tumors and Improves Antitumor Efficacy when Combined with Checkpoint Blockade
    1
    1. scibot 24 Feb 2021
      Plasmid_12259

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    cell.com/cancer-cell/abstract/S1535-6108(20)30597-3
  135. www.sciencedirect.com www.sciencedirect.com
    Centrosome amplification mediates small extracellular vesicle secretion via lysosome disruption
    1
    1. scibot 24 Feb 2021
      Addgene_12259

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    sciencedirect.com/science/article/pii/S0960982221000610
  136. www.sciencedirect.com www.sciencedirect.com
    The IMiD target CRBN determines HSP90 activity toward transmembrane proteins essential in multiple myeloma
    1
    1. scibot 24 Feb 2021
      RRID:Addgene_12259

      DOI: 10.1016/j.molcel.2020.12.046

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    sciencedirect.com/science/article/pii/S1097276520309886
  137. www.sciencedirect.com www.sciencedirect.com
    High-Throughput Screens of PAM-Flexible Cas9 Variants for Gene Knockout and Transcriptional Modulation
    1
    1. scibot 13 Feb 2021
      plasmid_12259

      DOI: 10.1016/j.celrep.2020.02.010

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    sciencedirect.com/science/article/pii/S2211124720301649
  138. cancerdiscovery.aacrjournals.org cancerdiscovery.aacrjournals.org
    Selection of Oncogenic Mutant Clones in Normal Human Skin Varies with Body Site
    1
    1. scibot 11 Feb 2021
      RRID:Addgene_12259

      DOI: 10.1158/2159-8290.CD-20-1092

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    cancerdiscovery.aacrjournals.org/content/11/2/340
  139. www.sciencedirect.com www.sciencedirect.com
    Gain-of-function p53 protein transferred via small extracellular vesicles promotes conversion of fibroblasts to a cancer-associated phenotype
    1
    1. scibot 11 Feb 2021
      Plasmid_12259

      DOI: 10.1016/j.celrep.2021.108726

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    sciencedirect.com/science/article/pii/S2211124721000395
  140. www.sciencedirect.com www.sciencedirect.com
    Quantitative analysis of dense-core vesicle fusion in rodent CNS neurons
    1
    1. scibot 09 Feb 2021
      Addgene: #12259

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    sciencedirect.com/science/article/pii/S2666166721000320
  141. elifesciences.org elifesciences.org
    Diverse viral proteases activate the NLRP1 inflammasome
    1
    1. scibot 09 Feb 2021
      RRID:Addgene_12259

      DOI: 10.7554/eLife.60609

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    elifesciences.org/articles/60609
  142. www.sciencedirect.com www.sciencedirect.com
    Chromatin 3D interaction analysis of the STARD10 locus unveils FCHSD2 as a regulator of insulin secretion
    1
    1. scibot 09 Feb 2021
      RRID:Addgene_12259

      DOI: 10.1016/j.celrep.2021.108703

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    sciencedirect.com/science/article/pii/S2211124721000164
  143. Jan 2021
  144. www.sciencedirect.com www.sciencedirect.com
    Optimized protocol for gene editing in adipocytes using CRISPR-Cas9 technology
    1
    1. scibot 29 Jan 2021
      pMD2.G

      DOI: 10.1016/j.xpro.2021.100307

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    sciencedirect.com/science/article/pii/S2666166721000149
  145. www.nature.com www.nature.com
    Decoding myofibroblast origins in human kidney fibrosis
    1
    1. scibot 29 Jan 2021
      RRID:Addgene_12259

      DOI: 10.1038/s41586-020-2941-1

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    nature.com/articles/s41586-020-2941-1
  146. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Further evidence supporting a potential role for ADH1B in obesity
    1
    1. scibot 29 Jan 2021
      RRID:Addgene_12259

      DOI: 10.1038/s41598-020-80563-z

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    ncbi.nlm.nih.gov/pmc/articles/PMC7820614/
  147. www.sciencedirect.com www.sciencedirect.com
    TBK1 and IKKε Act Redundantly to Mediate STING-Induced NF-κB Responses in Myeloid Cells
    1
    1. scibot 29 Jan 2021
      Plasmid_12259

      DOI: 10.1016/j.celrep.2020.03.056

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    sciencedirect.com/science/article/pii/S2211124720303703
  148. www.sciencedirect.com www.sciencedirect.com
    FOS licenses early events in stem cell activation driving skeletal muscle regeneration
    1
    1. scibot 27 Jan 2021
      Addgene_12259

      DOI: 10.1016/j.celrep.2020.108656

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    sciencedirect.com/science/article/pii/S2211124720316454
  149. www.sciencedirect.com www.sciencedirect.com
    Hotspots of Aberrant Enhancer Activity in Fibrolamellar Carcinoma Reveal Candidate Oncogenic Pathways and Therapeutic Vulnerabilities
    1
    1. scibot 27 Jan 2021
      plasmid_12259

      DOI: 10.1016/j.celrep.2020.03.073

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    sciencedirect.com/science/article/pii/S2211124720303995
  150. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signaling
    1
    1. scibot 26 Jan 2021
      RRID:Addgene_12259

      DOI: 10.1016/j.cell.2020.12.024

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    ncbi.nlm.nih.gov/pmc/articles/PMC7868890/
  151. www.sciencedirect.com www.sciencedirect.com
    The Tumour Suppressor TMEM127 Is a Nedd4-Family E3 Ligase Adaptor Required by Salmonella SteD to Ubiquitinate and Degrade MHC Class II Molecules
    1
    1. scibot 15 Jan 2021
      Plasmid_12259

      DOI: 10.1016/j.chom.2020.04.024

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    sciencedirect.com/science/article/pii/S1931312820302511
  152. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Manipulation of the human tRNA pool reveals distinct tRNA sets that act in cellular proliferation or cell cycle arrest
    1
    1. scibot 08 Jan 2021
      RRID:Addgene_12259

      DOI: 10.7554/eLife.58461

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    ncbi.nlm.nih.gov/pmc/articles/PMC7781600/
  153. www.sciencedirect.com www.sciencedirect.com
    Functional Genomics Identify Distinct and Overlapping Genes Mediating Resistance to Different Classes of Heterobifunctional Degraders of Oncoproteins
    1
    1. scibot 07 Jan 2021
      RRID: Addgene_12259

      DOI: 10.1016/j.celrep.2020.108532

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    sciencedirect.com/science/article/pii/S2211124720315217
  154. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Modeling Rett Syndrome With Human Patient-Specific Forebrain Organoids
    1
    1. scibot 07 Jan 2021
      RRID:Addgene_12259

      DOI: 10.3389/fcell.2020.610427

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    ncbi.nlm.nih.gov/pmc/articles/PMC7758289/
  155. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    High-Throughput CRISPR Screening Identifies Genes Involved in Macrophage Viability and Inflammatory Pathways
    1
    1. scibot 05 Jan 2021
      RRID:Addgene_12259

      DOI: 10.1016/j.celrep.2020.108541

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    ncbi.nlm.nih.gov/pmc/articles/PMC7901356/
  156. Dec 2020
  157. www.sciencedirect.com www.sciencedirect.com
    Synthetic Lethal Interaction between the ESCRT Paralog Enzymes VPS4A and VPS4B in Cancers Harboring Loss of Chromosome 18q or 16q
    1
    1. scibot 17 Dec 2020
      pMD2.G

      DOI: 10.1016/j.celrep.2020.108493

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    sciencedirect.com/science/article/pii/S2211124720314820
  158. www.sciencedirect.com www.sciencedirect.com
    Master Regulators and Cofactors of Human Neuronal Cell Fate Specification Identified by CRISPR Gene Activation Screens
    1
    1. scibot 07 Dec 2020
      Addgene_12259

      DOI: 10.1016/j.celrep.2020.108460

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    sciencedirect.com/science/article/pii/S2211124720314492
  159. www.authorea.com www.authorea.com
    Estrogen receptor alpha inhibits mesenchymal and amoeboidal movement of liver cancer cell via G protein subunit alpha 12
    1
    1. scibot 07 Dec 2020
      plasmid_12259

      DOI: 10.22541/au.160624514.40941389/v1

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    authorea.com/users/378507/articles/494981-estrogen-receptor-alpha-inhibits-mesenchymal-and-amoeboidal-movement-of-liver-cancer-cell-via-g-protein-subunit-alpha-12
  160. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The palmitoyl acyltransferase ZDHHC14 controls Kv1-family potassium channel clustering at the axon initial segment
    1
    1. scibot 07 Dec 2020
      RRID:Addgene_12259

      DOI: 10.7554/eLife.56058

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  161. www.sciencedirect.com www.sciencedirect.com
    Multiple Alternative Promoters and Alternative Splicing Enable Universal Transcription-Based Logic Computation in Mammalian Cells
    1
    1. scibot 07 Dec 2020
      Plasmid_12259

      DOI: 10.1016/j.celrep.2020.108437

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    sciencedirect.com/science/article/pii/S2211124720314261
  162. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-scale CRISPR screening at high sensitivity with an empirically designed sgRNA library
    1
    1. scibot 07 Dec 2020
      Addgene_12259

      DOI: 10.1186/s12915-020-00905-1

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    ncbi.nlm.nih.gov/pmc/articles/PMC7686728/
  163. Nov 2020
  164. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Requisite Chromatin Remodeling for Myeloid and Erythroid Lineage Differentiation from Erythromyeloid Progenitors
    2
    1. scibot 25 Nov 2020
      RRID:Addgene_12259

      DOI: 10.1016/j.celrep.2020.108395

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      plasmid_12259

      DOI: 10.1016/j.celrep.2020.108395

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  165. www.nature.com www.nature.com
    Raloxifene prevents stress granule dissolution, impairs translational control and promotes cell death during hypoxia in glioblastoma cells
    1
    1. scibot 24 Nov 2020
      plasmid_12259

      DOI: 10.1038/s41419-020-03159-5

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  166. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Homology-guided identification of a conserved motif linking the antiviral functions of IFITM3 to its oligomeric state
    1
    1. scibot 22 Nov 2020
      RRID:Addgene_12259

      DOI: 10.7554/eLife.58537

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    ncbi.nlm.nih.gov/pmc/articles/PMC7665892/
  167. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cytotoxic T cells swarm by homotypic chemokine signalling
    1
    1. scibot 21 Nov 2020
      RRID:Addgene_12259

      DOI: 10.7554/eLife.56554

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    ncbi.nlm.nih.gov/pmc/articles/PMC7669268/
  168. www.sciencedirect.com www.sciencedirect.com
    PICK1 Controls Activity-Dependent Synaptic Vesicle Cargo Retrieval
    1
    1. scibot 05 Nov 2020
      Plasmid_12259

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    sciencedirect.com/science/article/pii/S2211124720313012
  169. Oct 2020
  170. www.sciencedirect.com www.sciencedirect.com
    SARS-CoV-2 Infects the Brain Choroid Plexus and Disrupts the Blood-CSF Barrier in Human Brain Organoids
    1
    1. scibot 31 Oct 2020
      plasmid_12259

      DOI: 10.1016/j.stem.2020.10.001

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    sciencedirect.com/science/article/pii/S1934590920304951
  171. www.sciencedirect.com www.sciencedirect.com
    IL4I1 Is a Metabolic Immune Checkpoint that Activates the AHR and Promotes Tumor Progression
    1
    1. scibot 31 Oct 2020
      plasmid_12259

      DOI: 10.1016/j.cell.2020.07.038

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    sciencedirect.com/science/article/pii/S0092867420309466
  172. www.sciencedirect.com www.sciencedirect.com
    PPARα Inhibition Overcomes Tumor-Derived Exosomal Lipid-Induced Dendritic Cell Dysfunction
    1
    1. scibot 27 Oct 2020
      pMD2.G

      DOI: 10.1016/j.celrep.2020.108278

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    sciencedirect.com/science/article/pii/S2211124720312675
  173. elifesciences.org elifesciences.org
    Light-regulated allosteric switch enables temporal and subcellular control of enzyme activity
    1
    1. scibot 27 Oct 2020
      RRID:Addgene_12259

      DOI: 10.7554/eLife.60647

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    elifesciences.org/articles/60647
  174. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Schwannoma development is mediated by Hippo pathway dysregulation and modified by RAS/MAPK signaling
    1
    1. scibot 22 Oct 2020
      RRID:Addgene_12259

      DOI: 10.1172/jci.insight.141514

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    pubmed.ncbi.nlm.nih.gov/32960816/
  175. www.embopress.org www.embopress.org
    Identification of a dynamic gene regulatory network required for pluripotency factor‐induced reprogramming of mouse fibroblasts and hepatocytes
    1
    1. scibot 13 Oct 2020
      RRID:Addgene_12259

      DOI: 10.15252/embj.2019102236

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    embopress.org/doi/full/10.15252/embj.2019102236
  176. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Collagen-rich omentum is a premetastatic niche for integrin α2-mediated peritoneal metastasis
    1
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      DOI: 10.7554/eLife.59442

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    ncbi.nlm.nih.gov/pmc/articles/PMC7541088/
  177. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Respiratory Supercomplexes Promote Mitochondrial Efficiency and Growth in Severely Hypoxic Pancreatic Cancer
    1
    1. scibot 08 Oct 2020
      RRID:Addgene_12259

      DOI: 10.1016/j.celrep.2020.108231

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    pubmed.ncbi.nlm.nih.gov/33027658/
  178. www.sciencedirect.com www.sciencedirect.com
    MED19 Regulates Adipogenesis and Maintenance of White Adipose Tissue Mass by Mediating PPARγ-Dependent Gene Expression
    1
    1. scibot 07 Oct 2020
      pMD2.G

      DOI: 10.1016/j.celrep.2020.108228

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    sciencedirect.com/science/article/pii/S2211124720312171
  179. www.sciencedirect.com www.sciencedirect.com
    MYC Promotes Bone Marrow Stem Cell Dysfunction in Fanconi Anemia
    1
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      pMD2.G plasmid

      DOI: 10.1016/j.stem.2020.09.004

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    sciencedirect.com/science/article/pii/S1934590920304501
  180. Sep 2020
  181. www.sciencedirect.com www.sciencedirect.com
    Activation of CpG-Rich Promoters Mediated by MLL Drives MOZ-Rearranged Leukemia
    1
    1. scibot 30 Sep 2020
      Plasmid_12259

      DOI: 10.1016/j.celrep.2020.108200

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    sciencedirect.com/science/article/pii/S221112472031189X
  182. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Single point mutations within the Coxsackie B virus receptor-binding site promote resistance against soluble virus receptor traps
    1
    1. scibot 26 Sep 2020
      RRID Addgene 12259

      DOI: 10.1128/JVI.00952-20

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    pubmed.ncbi.nlm.nih.gov/32669334/
  183. www.sciencedirect.com www.sciencedirect.com
    Immune Sensing of Synthetic, Bacterial, and Protozoan RNA by Toll-like Receptor 8 Requires Coordinated Processing by RNase T2 and RNase 2
    1
    1. scibot 26 Sep 2020
      RRID:Addgene_12259

      DOI: 10.1016/j.immuni.2020.03.009

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    sciencedirect.com/science/article/pii/S1074761320301229
  184. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Perturbation of base excision repair sensitizes breast cancer cells to APOBEC3 deaminase-mediated mutations
    1
    1. scibot 26 Sep 2020
      RRID:Addgene_12259

      DOI: 10.7554/eLife.51605

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    ncbi.nlm.nih.gov/pmc/articles/PMC6961979/
  185. www.sciencedirect.com www.sciencedirect.com
    Caspase-6 Is a Key Regulator of Innate Immunity, Inflammasome Activation, and Host Defense
    1
    1. scibot 26 Sep 2020
      RRID:Addgene_12259

      DOI: 10.1016/j.cell.2020.03.040

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    sciencedirect.com/science/article/pii/S0092867420303330
  186. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SARS-CoV-2 Infection Depends on Cellular Heparan Sulfate and ACE2
    1
    1. scibot 26 Sep 2020
      plasmid_12259

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    ncbi.nlm.nih.gov/pmc/articles/PMC7489987/
  187. www.sciencedirect.com www.sciencedirect.com
    A drug screening toolkit based on the –1 ribosomal frameshifting of SARS-CoV-2
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    1. scibot 25 Sep 2020
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      DOI: 10.1016/j.heliyon.2020.e04793

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    sciencedirect.com/science/article/pii/S2405844020316364
  188. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Mutational resilience of antiviral restriction favors primate TRIM5α in host-virus evolutionary arms races
    2
    1. scibot 23 Sep 2020
      MD2.G

      DOI: 10.7554/eLife.59988

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      DOI: 10.7554/eLife.59988

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  189. www.sciencedirect.com www.sciencedirect.com
    RAI1 Regulates Activity-Dependent Nascent Transcription and Synaptic Scaling
    1
    1. scibot 23 Sep 2020
      RRID:Addgene_12259

      DOI: 10.1016/j.celrep.2020.108002

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    sciencedirect.com/science/article/pii/S2211124720309876
  190. journals.plos.org journals.plos.org
    TRIM34 restricts HIV-1 and SIV capsids in a TRIM5α-dependent manner
    1
    1. scibot 23 Sep 2020
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      DOI: 10.1371/journal.ppat.1008507

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    journals.plos.org/plospathogens/article
  191. rupress.org rupress.org
    GRAF2, WDR44, and MICAL1 mediate Rab8/10/11–dependent export of E-cadherin, MMP14, and CFTR ΔF508
    1
    1. scibot 23 Sep 2020
      RRID:Addgene_12259

      DOI: 10.1083/jcb.201811014

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    rupress.org/jcb/article/219/5/e201811014/151714/GRAF2-WDR44-and-MICAL1-mediate-Rab8-10-11
  192. www.frontiersin.org www.frontiersin.org
    A20 Restricts Inflammatory Response and Desensitizes Gingival Keratinocytes to Apoptosis
    1
    1. scibot 17 Sep 2020
      RRID:Addgene_12259

      DOI: 10.3389/fimmu.2020.00365

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    frontiersin.org/article/10.3389/fimmu.2020.00365/full
  193. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Malignant Transformation Involving CXXC4 Mutations Identified in a Leukemic Progression Model of Severe Congenital Neutropenia
    1
    1. scibot 17 Sep 2020
      RRID:Addgene_12259

      DOI: 10.1016/j.xcrm.2020.100074

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    pubmed.ncbi.nlm.nih.gov/33205068/
  194. elifesciences.org elifesciences.org
    Modulation of dopamine D1 receptors via histamine H3 receptors is a novel therapeutic target for Huntington's disease
    1
    1. scibot 17 Sep 2020
      Addgene_12259

      DOI: 10.7554/eLife.51093

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    elifesciences.org/articles/51093
  195. www.sciencedirect.com www.sciencedirect.com
    An Evolutionary Insertion in the Mxra8 Receptor-Binding Site Confers Resistance to Alphavirus Infection and Pathogenesis
    1
    1. scibot 16 Sep 2020
      RRID:Addgene_12259

      DOI: 10.1016/j.chom.2020.01.008

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    sciencedirect.com/science/article/pii/S1931312820300470
  196. elifesciences.org elifesciences.org
    A human ESC-based screen identifies a role for the translated lncRNA LINC00261 in pancreatic endocrine differentiation
    1
    1. scibot 16 Sep 2020
      RRID:Addgene_12259

      DOI: 10.7554/eLife.58659

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    elifesciences.org/articles/58659
  197. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Proteasome inhibitor-induced modulation reveals the spliceosome as a specific therapeutic vulnerability in multiple myeloma
    1
    1. scibot 16 Sep 2020
      Plasmid_12259

      DOI: 10.1038/s41467-020-15521-4

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    ncbi.nlm.nih.gov/pmc/articles/PMC7176739/
  198. www.sciencedirect.com www.sciencedirect.com
    Super-Enhancer Redistribution as a Mechanism of Broad Gene Dysregulation in Repeatedly Drug-Treated Cancer Cells
    1
    1. scibot 16 Sep 2020
      RRID:Addgene_12259

      DOI: 10.1016/j.celrep.2020.107532

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    sciencedirect.com/science/article/pii/S2211124720304320
  199. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    YAP regulates cell size and growth dynamics via non-cell autonomous mediators
    1
    1. scibot 16 Sep 2020
      RRID:Addgene_12259

      DOI: 10.7554/eLife.53404

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    ncbi.nlm.nih.gov/pmc/articles/PMC6989120/
  200. link.springer.com link.springer.com
    Impaired differentiation of human induced neural stem cells by TOR1A overexpression
    1
    1. scibot 16 Sep 2020
      RRID:Addgene_12259

      DOI: 10.1007/s11033-020-05390-x

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    link.springer.com/article/10.1007/s11033-020-05390-x
  201. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    High-Throughput, Temporal and Dose Dependent, Effect of Vitamins and Minerals on Chondrogenesis
    1
    1. scibot 15 Sep 2020
      RRID:Addgene_12259

      DOI: 10.3389/fcell.2020.00092

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    ncbi.nlm.nih.gov/pmc/articles/PMC7053227/
  202. www.mdpi.com www.mdpi.com
    Isolation of Human Small Extracellular Vesicles and Tracking of their Uptake by Retinal Pigment Epithelial Cells In Vitro
    1
    1. scibot 15 Sep 2020
      RRID:Addgene_12259

      DOI: 10.3390/ijms21113799

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    mdpi.com/1422-0067/21/11/3799
  203. www.nature.com www.nature.com
    Locoregional delivery of CAR T cells to the cerebrospinal fluid for treatment of metastatic medulloblastoma and ependymoma
    1
    1. scibot 15 Sep 2020
      RRID:Addgene_12259

      DOI: 10.1038/s41591-020-0827-2

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    nature.com/articles/s41591-020-0827-2