4,026 Matching Annotations
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  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    An epigenetic bifunctional that toggles between transactivation and repression
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    pmc.ncbi.nlm.nih.gov/articles/PMC13015318/
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    Therapeutic scheduling of WEE1 inhibition preserves T cell function and promotes immune control of HPV+ tumors
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    pmc.ncbi.nlm.nih.gov/articles/PMC13015432/
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    Integrative screening identifies functional variants and VNTRs underlying GWAS signals at the 5p15.33 multi-cancer susceptibility locus
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    pmc.ncbi.nlm.nih.gov/articles/PMC13001379/
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    circOMA1 delivered by exosomes regulates DRD2-mediated prolactinoma resistance
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    pmc.ncbi.nlm.nih.gov/articles/PMC13042270/
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    Co-delivery of IL-12/IL-15/IL-18 engineered DC vaccines with anti-IL-10R and nanoconjugated methotrexate in melanoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12989403/
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    IFNγ-induced antigen loss in chimeric antigen receptor-T cell therapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC13036235/
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    CENPF Overexpression Induced by HBV Infection Facilitates the G1/S Cell Cycle Transition of Hepatocellular Carcinoma Cells via MYC Pathway
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    pmc.ncbi.nlm.nih.gov/articles/PMC13051194/
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    Mechanistic dissection of GRHL2 and PR transcriptional co-regulation in breast cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC13008249/
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    Allele-selective disruption of pathogenic VWF variants in type 2 von Willebrand disease using CRISPR/Cas9
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    pmc.ncbi.nlm.nih.gov/articles/PMC12952769/
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    IFN signaling is associated with radiotherapy response in malignant peripheral nerve sheath tumors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12948414/
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    Androgen receptor drives polyamine synthesis creating a vulnerability for prostate cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12758111/
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    Targeted inhibition of Nrf2 potentiates antitumor immunity and enhances the efficacy of immunotherapy in hepatocellular carcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC13034291/
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    Integrative analysis of mRNA stability regulation uncovers a metastasis-suppressive program in breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12978252/
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    KLF5 controls subtype-independent highly interactive enhancers in pancreatic cancer to regulate cell survival
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    pmc.ncbi.nlm.nih.gov/articles/PMC12998525/
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    CLOCK-catalyzed histone H3K37 glutarylation suppresses H3K36 trimethylation pathways in glioblastoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC13015892/
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    Regulation of sodium/calcium homeostasis by BacNav gene therapy rescues cardiac dysfunction in chronic heart failure
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    pmc.ncbi.nlm.nih.gov/articles/PMC13004020/
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    EP4 influences bortezomib resistance in multiple myeloma by modulating endoplasmic reticulum stress via the phosphatidylinositol 3-kinase/protein kinase B pathway
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    pmc.ncbi.nlm.nih.gov/articles/PMC12955957/
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    ZXDB Drives Macrophage Inflammatory Programming in Sepsis‐Induced Acute Kidney Injury by Recruiting EIF4A3 to Enhance ACACA Translation
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    pmc.ncbi.nlm.nih.gov/articles/PMC13011163/
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    HPV16 E6 oncoprotein promotes microhomology-mediated viral integration by increasing PolΘ protein expression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12974484/
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    A targeting lentiviral vector for generation of CAR-T cells in vivo
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    pmc.ncbi.nlm.nih.gov/articles/PMC13009191/
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    Loss-of-function variants in ODAD1 disrupt ODA docking and induce actin cytoskeletal remodeling in primary ciliary dyskinesia
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    pmc.ncbi.nlm.nih.gov/articles/PMC13039848/
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    The EHMT2-MBLAC2 axis suppresses ribosomal DNA transcription in response to nucleolar DNA damage
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    pmc.ncbi.nlm.nih.gov/articles/PMC13039405/
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    Androgen receptor-dependent DRAM1 activation drives autophagic resistance to BRAF inhibitors in BRAFV600-mutant melanoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC13004951/
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    CRISPR/Cas-based activation of PPARGC1A boosts endogenous mitochondria and enhances cardiac function and recovery after myocardial infarction
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    pmc.ncbi.nlm.nih.gov/articles/PMC13045639/
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    The HIF-2 Transcription Factor Mediates Resistance to Ferroptosis in Pancreatic Cancer
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    SDF2L1 modulates oxLDL-induced endoplasmic reticulum stress, protein aggregation, and O-mannosylation in myocardial infarction and lung cancer
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    Reprogramming mRNA localization by targeted RNA-protein interference
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    mtDNA-Depleted Mitochondria Form Sites of Contact with the Nucleus and Alter the Cellular Epigenome
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    Defining the functional role and potential as an immunotherapeutic target of ALCAM in neuroblastoma
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    CHK1 is an integral regulator of DNA replication in human cells
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    PRAS40 activates the IRE1α-XBP-1-mediated unfolded protein response to exacerbate colorectal cancer by enhancing ST6Gal1-dependent α-2, 6 sialylation of GRP78
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    MEX3B is a positive pan-inflammasome regulator
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    Claudins interact with LILRB immune inhibitory receptors to promote myeloid immunosuppression in cancer
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    Patient-derived kidney organoids recapitulate ADPKD and facilitate the identification of Rho pathway inhibitors as candidate therapeutics
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    AURKA-mediated destabilization of SAPS3 drives ferroptosis evasion via 7-dehydrocholesterol biosynthesis in colorectal cancer
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    Dual function of DOT1L suppresses tumor cell-intrinsic immunogenicity in hepatocellular carcinoma
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  43. Apr 2026
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    Cep192 insufficiency underlies haploid instability in human cells
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    Interactome mapping in human excitatory neurons reveals novel risk genes and pathways in Alzheimer’s disease
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    Endoplasmic Reticulum Geometry Dictates Neuronal Bursting via Calcium Store Refill Rates and Exposes Selective Neuronal Vulnerability
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    Combined inactivation of MEK and mTOR can lead to synergistic cell death in glioblastoma models and associates with NF1-deficiency and a mesenchymal subtype
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    Metabolic Response to CDK4/6 Inhibition in ER+ Breast Cancer Creates a Therapeutic Vulnerability in Drug-Tolerant Persister Cells
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    IFIT3 Associates with m⁶A-Modified RNA to Restrict Hepatitis C Virus Infection
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    Pre-existing cell states predict resistance to multiple treatments
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    Three-dimensional reconstruction of a biliary system in a bioengineered liver using decellularized scaffold
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    Mechanically-induced Septin Networks Protect Nuclear Integrity
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    Establishment of a 3D Multicellular HCC Tumor Spheroid Model to Unravel Nrf2’s Influence on the Tumor Immune Microenvironment
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    Identification and structural characterization of anthrax toxin receptor 2 as the Clostridium perfringens NetF receptor
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    Oncogenic alterations in PI3K signaling emulated optogenetically recapitulates some phenotypic changes in mammary epithelia
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    CRISPR screens in iPSC-derived neurons reveal principles of tau proteostasis
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    Integrating traditional omics and AI-driven approaches for discovery and validation of novel MicroRNA biomarkers and therapeutic targets in thyroid cancer
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    CELF2 Promotes Tau Exon 10 Inclusion via Hinge Domain-Mediated Nuclear Condensation, Driving Cognitive Dysfunction in Tauopathy Models
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    Integrated phenotypic screening and chemical proteomics identifies ETF1 ligands that modulate viral translation and replication
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    Splice isoform-perturbation coupled to single cell transcriptome profiling reveals functions of microexons in neurogenesis and autism-linked pathways
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    Protocol for stable cell line production to express muscle-type nicotinic receptor
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    Dominant-negative TP53 mutations potentiated by the HSF1-regulated proteostasis network
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    Uev1A counteracts oncogenic Ras stimuli in both polyploid and diploid cells
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    Dual receptor engagement by mannose-capped lipoarabinomannan reprograms macrophage lipid metabolism in tuberculosis
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    CRISPR-Drug Combinatorial Screening Identifies Effective Combination Treatments for MTAP-deleted cancer
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    Protocol to generate immunocompetent human heart-macrophage assembloids for the study of immune-cardiac interactions
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    TIPE2 knockdown enhances the anti-tumor efficacy of NKG2D CAR-T cells against pancreatic cancer via activating NF-κb signaling pathway
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    Nanobody-Engineered CLL-1 CAR-T Cells: Optimizing Tumor-Specific Cytotoxicity and Minimizing Off-Tumor Toxicity
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    Uncovering NMDA receptor-mediated high firing activity in excitatory human neurons
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    New selective and allosteric FLT3 inhibitors show efficacy against resistant acute myeloid leukemia cells
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    Deubiquitinating enzyme MINDY2 regulates TNF-α-induced cell death by targeting RIPK1
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    Autoinhibitory control of MLKL governs pseudokinase domain phosphorylation and oligomerization during necroptosis
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    Radiotherapy synergizes with an inducible AAV-based immunotherapy platform to program local and systemic antitumor immunity
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    sciencedirect.com/science/article/pii/S153561082600111X
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    Development and validation of a PSMA-positive triple-negative breast cancer mouse model for preclinical targeted radionuclide therapies
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    RNF25 confers mRNA damage tolerance by curbing activation of the integrated stress response
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    Distinct synaptic mechanisms underlie NRXN1 variant and disorder background-dependent phenotypes in iPSC-derived neurons
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    sciencedirect.com/science/article/pii/S2211124726001932
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    Plasma extracellular vesicle modulate immune cell transcriptional responses following acute myocardial infarction
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    Functional chromatin signatures premark future lineage-specific enhancers
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    A bispecific nanobody-drug conjugate targeting TROP2 and c-Met for low-concentration, single-dose treatment of pancreatic cancer
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    Mitochondrial control of glycerolipid synthesis by a PEP shuttle
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    sciencedirect.com/science/article/pii/S0092867426002242
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    Polθ activity modulates sensitivity to standard therapies in DNMT3A-deficient leukemia
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    ER-tethering directs TREX1 penetration of a BAF-dependent barrier at micronuclei
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    Promoter mutagenesis and a massively parallel reporter screen of the MAPT locus identifies cis-regulatory elements and genetic variation effects
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    biorxiv.org/content/10.64898/2026.03.06.710116v1
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    NIPAL1 Drives a Metabolic-Epigenetic Feedback Loop to Promote Lactate-Mediated Immune Evasion in Esophageal Cancer
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    advanced.onlinelibrary.wiley.com/doi/full/10.1002/advs.202520055
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  177. www.science.org www.science.org
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