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  1. Jan 2020
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    The Pseudo Natural Product Myokinasib Is a Myosin Light Chain Kinase 1 Inhibitor with Unprecedented Chemotype
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    Small‐molecule inhibition of prostaglandin E receptor 2 impairs cyclooxygenase‐associated malignant glioma growth
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    Suppressing Mitochondrial Respiration Is Critical for Hypoxia Tolerance in the Fetal Growth Plate
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    Oncogenic Notch Promotes Long-Range Regulatory Interactions within Hyperconnected 3D Cliques
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    Mesenchymal Niche-Specific Expression of Cxcl12 Controls Quiescence of Treatment-Resistant Leukemia Stem Cells
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    DNA Replication Vulnerabilities Render Ovarian Cancer Cells Sensitive to Poly(ADP-Ribose) Glycohydrolase Inhibitors
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    Monocyte-Derived CD11c+ Cells Acquire Plasmodium from Hepatocytes to Prime CD8 T Cell Immunity to Liver-Stage Malaria
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    Essential Gene Profiles for Human Pluripotent Stem Cells Identify Uncharacterized Genes and Substrate Dependencies
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    Interstitial Migration of CD8αβ T Cells in the Small Intestine Is Dynamic and Is Dictated by Environmental Cues
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    1,2,3,4,6‐Penta‐O‐galloyl‐β‐d‐glucose modulates perivascular inflammation and prevents vascular dysfunction in angiotensin II‐induced hypertension
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    A Multiplexed Assay for Exon Recognition Reveals that an Unappreciated Fraction of Rare Genetic Variants Cause Large-Effect Splicing Disruptions
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    HIF-1α Is a Metabolic Switch between Glycolytic-Driven Migration and Oxidative Phosphorylation-Driven Immunosuppression of Tregs in Glioblastoma
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    Schwann cells, but not Oligodendrocytes, Depend Strictly on Dynamin 2 Function
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    Developmental changes in interkinetic nuclear migration dynamics with respect to cell‐cycle progression in the mouse cerebral cortex ventricular zone
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    Social Stress Mobilizes Hematopoietic Stem Cells to Establish Persistent Splenic Myelopoiesis
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    CCL5 promotes breast cancer recurrence through macrophage recruitment in residual tumors
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    Unravelling Intratumoral Heterogeneity through High-Sensitivity Single-Cell Mutational Analysis and Parallel RNA Sequencing
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    A conserved major facilitator superfamily member orchestrates a subset of O-glycosylation to aid macrophage tissue invasion
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    Isoforms of RNA-Editing Enzyme ADAR1 Independently Control Nucleic Acid Sensor MDA5-Driven Autoimmunity and Multi-organ Development
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    Opposing Effects of Membrane-Anchored CX3CL1 on Amyloid and Tau Pathologies via the p38 MAPK Pathway
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    Single-Dose CpG Immunization Protects Against a Heterosubtypic Challenge and Generates Antigen-Specific Memory T Cells
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    A postnatal peak in microglial development in the mouse hippocampus is correlated with heightened sensitivity to seizure triggers
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    Blocking Stroke-Induced Immunodeficiency Increases CNS Antigen-Specific Autoreactivity But Does Not Worsen Functional Outcome after Experimental Stroke
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    Characterization of Oligodendroglial Populations in Mouse Demyelinating Disease Using Flow Cytometry: Clues for MS Pathogenesis
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    The FOXO1 Transcription Factor Instructs the Germinal Center Dark Zone Program
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  54. Nov 2018
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    RHOA G17V Induces T Follicular Helper Cell Specification and Promotes Lymphomagenesis
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    CD157 Marks Tissue-Resident Endothelial Stem Cells with Homeostatic and Regenerative Properties
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    The Histone Chaperones ASF1 and CAF-1 Promote MMS22L-TONSL-Mediated Rad51 Loading onto ssDNA during Homologous Recombination in Human Cells
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    Tumor-Repopulating Cells Induce PD-1 Expression in CD8+ T Cells by Transferring Kynurenine and AhR Activation
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    Genome-wide CRISPR-Cas9 Screen Identifies Leukemia-Specific Dependence on a Pre-mRNA Metabolic Pathway Regulated by DCPS
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    Commensal Microbes Induce Serum IgA Responses that Protect against Polymicrobial Sepsis
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    Dual Modifications of α-Galactosylceramide Synergize to Promote Activation of Human Invariant Natural Killer T Cells and Stimulate Anti-tumor Immunity
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    IRF8 Regulates Transcription of Naips for NLRC4 Inflammasome Activation
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    Ribosome Levels Selectively Regulate Translation and Lineage Commitment in Human Hematopoiesis
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    Synergy between the KEAP1/NRF2 and PI3K Pathways Drives Non-Small-Cell Lung Cancer with an Altered Immune Microenvironment
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    Cholesterol Homeostatic Regulator SCAP-SREBP2 Integrates NLRP3 Inflammasome Activation and Cholesterol Biosynthetic Signaling in Macrophages
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    The Histone Chaperone FACT Coordinates H2A.X-Dependent Signaling and Repair of DNA Damage
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    Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme Formation
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    CtIP-Mediated Fork Protection Synergizes with BRCA1 to Suppress Genomic Instability upon DNA Replication Stress
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    Protein Barcodes Enable High-Dimensional Single-Cell CRISPR Screens
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    TLR8-Mediated Metabolic Control of Human Treg Function: A Mechanistic Target for Cancer Immunotherapy
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    Dysregulated Microbial Fermentation of Soluble Fiber Induces Cholestatic Liver Cancer
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    Targeting Processive Transcription Elongation via SEC Disruption for MYC-Induced Cancer Therapy
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    The Lineage-Defining Transcription Factors SOX2 and NKX2-1 Determine Lung Cancer Cell Fate and Shape the Tumor Immune Microenvironment
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    ZNF598 Is a Quality Control Sensor of Collided Ribosomes
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    Tumor-Derived cGAMP Triggers a STING-Mediated Interferon Response in Non-tumor Cells to Activate the NK Cell Response
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    CRISPR-Mediated Programmable 3D Genome Positioning and Nuclear Organization
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    Metformin Targets Mitochondrial Electron Transport to Reduce Air-Pollution-Induced Thrombosis
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    CD8+ T Cell Priming in Established Chronic Viral Infection Preferentially Directs Differentiation of Memory-like Cells for Sustained Immunity
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    Distinct Effector B Cells Induced by Unregulated Toll-like Receptor 7 Contribute to Pathogenic Responses in Systemic Lupus Erythematosus
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    The Majority of CD45– Ter119– CD31– Bone Marrow Cell Fraction Is of Hematopoietic Origin and Contains Erythroid and Lymphoid Progenitors
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    Complement C5a Fosters Squamous Carcinogenesis and Limits T Cell Response to Chemotherapy
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  85. www.sciencedirect.com www.sciencedirect.com
    MYC Interacts with the G9a Histone Methyltransferase to Drive Transcriptional Repression and Tumorigenesis
    1
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      FlowJo

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    Muscle Satellite Cell Cross-Talk with a Vascular Niche Maintains Quiescence via VEGF and Notch Signaling
    1
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    Intestinal Dysmotility Syndromes following Systemic Infection by Flaviviruses
    1
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      FlowJo

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  88. www.sciencedirect.com www.sciencedirect.com
    Inheritance of CENP-A Nucleosomes during DNA Replication Requires HJURP
    1
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      FlowJo

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    Immune Checkpoint Inhibition Overcomes ADCP-Induced Immunosuppression by Macrophages
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      FlowJo

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    Genetic Modulation of RNA Splicing with a CRISPR-Guided Cytidine Deaminase
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    Single-Cell Transcriptomic Analysis of Cardiac Differentiation from Human PSCs Reveals HOPX-Dependent Cardiomyocyte Maturation
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      FlowJo

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    An Endothelial-to-Adipocyte Extracellular Vesicle Axis Governed by Metabolic State
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      FlowJo

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  93. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Sulfatide isoform pattern in cerebrospinal fluid discriminates progressive MS from relapsing‐remitting MS
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      FlowJo

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    CD8+ T Cell Activation Leads to Constitutive Formation of Liver Tissue-Resident Memory T Cells that Seed a Large and Flexible Niche in the Liver
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      FlowJo

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    Type I Interferon Receptor Signaling of Neurons and Astrocytes Regulates Microglia Activation during Viral Encephalitis
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      FlowJo

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    Secreted IgD Amplifies Humoral T Helper 2 Cell Responses by Binding Basophils via Galectin-9 and CD44
    1
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      FlowJo

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    Regulatory T Cells Promote Macrophage Efferocytosis during Inflammation Resolution
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      FlowJo

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    B Cells Are the Dominant Antigen-Presenting Cells that Activate Naive CD4+ T Cells upon Immunization with a Virus-Derived Nanoparticle Antigen
    1
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      FlowJo

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    The Mevalonate Pathway Is a Druggable Target for Vaccine Adjuvant Discovery
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      FlowJo

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  100. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  101. www.sciencedirect.com www.sciencedirect.com
    Subversion of Systemic Glucose Metabolism as a Mechanism to Support the Growth of Leukemia Cells
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      Flowjo

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    Epigenetic Restoration of Fetal-like IGF1 Signaling Inhibits Leukemia Stem Cell Activity
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    NONO Detects the Nuclear HIV Capsid to Promote cGAS-Mediated Innate Immune Activation
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      Flow-Jo

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    Vascular and Neurogenic Rejuvenation in Aging Mice by Modulation of ASM
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      FlowJo

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    A Metabolism-Based Quorum Sensing Mechanism Contributes to Termination of Inflammatory Responses
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      FlowJo

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    The BRCT Domains of the BRCA1 and BARD1 Tumor Suppressors Differentially Regulate Homology-Directed Repair and Stalled Fork Protection
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      FlowJo

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    Prospective Isolation and Characterization of Genetically and Functionally Distinct AML Subclones
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      FlowJo

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    Translational and HIF-1α-Dependent Metabolic Reprogramming Underpin Metabolic Plasticity and Responses to Kinase Inhibitors and Biguanides
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      FlowJo

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    sciencedirect.com/science/article/pii/S1550413118305667
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  110. elifesciences.org elifesciences.org
    Glutathione de novo synthesis but not recycling process coordinates with glutamine catabolism to control redox homeostasis and directs murine T cell differentiation
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    elifesciences.org/articles/36158
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    A Functionally Defined In Vivo Astrocyte Population Identified by c-Fos Activation in a Mouse Model of Multiple Sclerosis Modulated by S1P Signaling: Immediate-Early Astrocytes (ieAstrocytes)
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    LC3-Associated Phagocytosis in Myeloid Cells Promotes Tumor Immune Tolerance
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      FlowJo

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  113. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Early Targeting of L-Selectin on Leukocytes Promotes Recovery after Spinal Cord Injury, Implicating Novel Mechanisms of Pathogenesis
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      FlowJo

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  114. www.sciencedirect.com www.sciencedirect.com
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    SYK-CARD9 Signaling Axis Promotes Gut Fungi-Mediated Inflammasome Activation to Restrict Colitis and Colon Cancer
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    The Adaptor Protein CARD9 Protects against Colon Cancer by Restricting Mycobiota-Mediated Expansion of Myeloid-Derived Suppressor Cells
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      Flow Jo

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    CD56 Expression Marks Human Group 2 Innate Lymphoid Cell Divergence from a Shared NK Cell and Group 3 Innate Lymphoid Cell Developmental Pathway
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      FlowJo

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    An Atypical Parvovirus Drives Chronic Tubulointerstitial Nephropathy and Kidney Fibrosis
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      FlowJo

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    A Bacterial Chromosome Structuring Protein Binds Overtwisted DNA to Stimulate Type II Topoisomerases and Enable DNA Replication
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      FlowJo

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    The Inhibitory Innate Immune Sensor NLRP12 Maintains a Threshold against Obesity by Regulating Gut Microbiota Homeostasis
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      Flowjo

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    sciencedirect.com/science/article/pii/S1931312818304372
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    A Membrane Potential- and Calpain-Dependent Reversal of Caspase-1 Inhibition Regulates Canonical NLRP3 Inflammasome
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      FlowJo

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  122. elifesciences.org elifesciences.org
    Tryparedoxin peroxidase-deficiency commits trypanosomes to ferroptosis-type cell death
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      FlowJo

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    The Ciliary Machinery Is Repurposed for T Cell Immune Synapse Trafficking of LCK
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      FlowJo

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    Disruption of the β1L Isoform of GABP Reverses Glioblastoma Replicative Immortality in a TERT Promoter Mutation-Dependent Manner
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      FlowJo

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    Mutant NPM1 Maintains the Leukemic State through HOX Expression
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    POLE3-POLE4 Is a Histone H3-H4 Chaperone that Maintains Chromatin Integrity during DNA Replication
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    MEF2B Instructs Germinal Center Development and Acts as an Oncogene in B Cell Lymphomagenesis
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    Identification of Chemotherapy-Induced Leukemic-Regenerating Cells Reveals a Transient Vulnerability of Human AML Recurrence
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    β-Hydroxybutyrate Prevents Vascular Senescence through hnRNP A1-Mediated Upregulation of Oct4
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    Transcriptional and Translational Differences of Microglia from Male and Female Brains
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    ATR-Mediated Global Fork Slowing and Reversal Assist Fork Traverse and Prevent Chromosomal Breakage at DNA Interstrand Cross-Links
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    Insulin Receptor-Mediated Stimulation Boosts T Cell Immunity during Inflammation and Infection
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    Neurons under T Cell Attack Coordinate Phagocyte-Mediated Synaptic Stripping
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    Daily Onset of Light and Darkness Differentially Controls Hematopoietic Stem Cell Differentiation and Maintenance
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    Flow Cytometry of Mouse and Human Adipocytes for the Analysis of Browning and Cellular Heterogeneity
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    NO-Dependent Akt Inactivation by S-Nitrosylation as a Possible Mechanism of STZ-Induced Neuronal Insulin Resistance
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    Self-Maintaining Gut Macrophages Are Essential for Intestinal Homeostasis
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    The Chemokine Receptor CCR8 Promotes the Migration of Dendritic Cells into the Lymph Node Parenchyma to Initiate the Allergic Immune Response
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    Lung γδ T Cells Mediate Protective Responses during Neonatal Influenza Infection that Are Associated with Type 2 Immunity
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    Gasdermin D Restrains Type I Interferon Response to Cytosolic DNA by Disrupting Ionic Homeostasis
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  144. onlinelibrary.wiley.com onlinelibrary.wiley.com
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    A Map of Toll-like Receptor Expression in the Intestinal Epithelium Reveals Distinct Spatial, Cell Type-Specific, and Temporal Patterns
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    Non-canonical NF-κB Antagonizes STING Sensor-Mediated DNA Sensing in Radiotherapy
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    TBK1 Suppresses RIPK1-Driven Apoptosis and Inflammation during Development and in Aging
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    SIRT1 Activation Disrupts Maintenance of Myelodysplastic Syndrome Stem and Progenitor Cells by Restoring TET2 Function
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    Memory B Cells Activate Brain-Homing, Autoreactive CD4+ T Cells in Multiple Sclerosis
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    Quiescent Endothelial Cells Upregulate Fatty Acid β-Oxidation for Vasculoprotection via Redox Homeostasis
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    Alveolar Macrophages Provide an Early Mycobacterium tuberculosis Niche and Initiate Dissemination
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  154. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Establishment and characterization of a telomerase‐immortalized porcine bronchial epithelial cell line
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    A Chromatin Basis for Cell Lineage and Disease Risk in the Human Pancreas
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    A Single-Agent Dual-Specificity Targeting of FOLR1 and DR5 as an Effective Strategy for Ovarian Cancer
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    Histone Ubiquitination by the DNA Damage Response Is Required for Efficient DNA Replication in Unperturbed S Phase
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    Neutralizing Gatad2a-Chd4-Mbd3/NuRD Complex Facilitates Deterministic Induction of Naive Pluripotency
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    Cytosolic Aspartate Availability Determines Cell Survival When Glutamine Is Limiting
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    GATA/Heme Multi-omics Reveals a Trace Metal-Dependent Cellular Differentiation Mechanism
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    Hoxc-Dependent Mesenchymal Niche Heterogeneity Drives Regional Hair Follicle Regeneration
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  163. elifesciences.org elifesciences.org
    Antibiotic-induced acceleration of type 1 diabetes alters maturation of innate intestinal immunity
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    Dissecting the Functional Consequences of De Novo DNA Methylation Dynamics in Human Motor Neuron Differentiation and Physiology
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    Dysregulated IL-18 Is a Key Driver of Immunosuppression and a Possible Therapeutic Target in the Multiple Myeloma Microenvironment
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    Integrated analysis of DNA methylome and transcriptome identified CREB5 as a novel risk gene contributing to recurrent pregnancy loss
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    Urea Cycle Dysregulation Generates Clinically Relevant Genomic and Biochemical Signatures
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      FlowJo

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    Distinct Bone Marrow Sources of Pleiotrophin Control Hematopoietic Stem Cell Maintenance and Regeneration
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    Tbx6 Induces Nascent Mesoderm from Pluripotent Stem Cells and Temporally Controls Cardiac versus Somite Lineage Diversification
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  171. www-sciencedirect-com.ezp-prod1.hul.harvard.edu www-sciencedirect-com.ezp-prod1.hul.harvard.edu
    Generation of Tumor-Reactive T Cells by Co-culture of Peripheral Blood Lymphocytes and Tumor Organoids
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  172. www.sciencedirect.com www.sciencedirect.com
    LIGHT-HVEM Signaling in Innate Lymphoid Cell Subsets Protects Against Enteric Bacterial Infection
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    LAG3+ Regulatory T Cells Restrain Interleukin-23-Producing CX3CR1+ Gut-Resident Macrophages during Group 3 Innate Lymphoid Cell-Driven Colitis
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      FlowJo

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    Conventional and Neo-Antigenic Peptides Presented by β Cells Are Targeted by Circulating Naïve CD8+ T Cells in Type 1 Diabetic and Healthy Donors
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      FlowJo

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    Dual Roles of Poly(dA:dT) Tracts in Replication Initiation and Fork Collapse
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      FlowJo

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    Genome-wide Map of R-Loop-Induced Damage Reveals How a Subset of R-Loops Contributes to Genomic Instability
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      FlowJo

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    Human iPSC-Derived Natural Killer Cells Engineered with Chimeric Antigen Receptors Enhance Anti-tumor Activity
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      FlowJo

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    Id1 Ablation Protects Hematopoietic Stem Cells from Stress-Induced Exhaustion and Aging
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      Flowjo

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    Glycan Masking Focuses Immune Responses to the HIV-1 CD4-Binding Site and Enhances Elicitation of VRC01-Class Precursor Antibodies
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      FlowJo

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    Selective Inhibition of Sialic Acid-Based Molecular Mimicry in Haemophilus influenzae Abrogates Serum Resistance
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      FlowJo

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    Th17 Lymphocytes Induce Neuronal Cell Death in a Human iPSC-Based Model of Parkinson’s Disease
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    Hyaluronan Receptor LYVE-1-Expressing Macrophages Maintain Arterial Tone through Hyaluronan-Mediated Regulation of Smooth Muscle Cell Collagen
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      Flowjo

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    FANCA Promotes DNA Double-Strand Break Repair by Catalyzing Single-Strand Annealing and Strand Exchange
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      Flow-jo

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    Subcellular Hsp70 Inhibitors Promote Cancer Cell Death via Different Mechanisms
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      FlowJo

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    Loss of PRMT5 Promotes PDGFRα Degradation during Oligodendrocyte Differentiation and Myelination
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      FlowJo

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    Isolation of a Structural Mechanism for Uncoupling T Cell Receptor Signaling from Peptide-MHC Binding
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      FlowJo

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  187. www.cell.com www.cell.com
    A Gut Commensal-Produced Metabolite Mediates Colonization Resistance to Salmonella Infection
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      FlowJo

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    Peroxisome Proliferator-Activated Receptor γ Is Essential for the Resolution of Staphylococcus aureus Skin Infections
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      FlowJo

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    Airway Epithelial Cell-Derived Colony Stimulating Factor-1 Promotes Allergen Sensitization
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      FlowJo

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    PD-1 Inhibitory Receptor Downregulates Asparaginyl Endopeptidase and Maintains Foxp3 Transcription Factor Stability in Induced Regulatory T Cells
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    Etomoxir Inhibits Macrophage Polarization by Disrupting CoA Homeostasis
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      FlowJo

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    α-Toxin Induces Platelet Aggregation and Liver Injury during Staphylococcus aureus Sepsis
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      FlowJo

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    Mapping the Genetic Landscape of Human Cells
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      FlowJo

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  194. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    ncbi.nlm.nih.gov/pmc/articles/PMC6035285/
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    Gut Microbiota-Stimulated Innate Lymphoid Cells Support β-Defensin 14 Expression in Pancreatic Endocrine Cells, Preventing Autoimmune Diabetes
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      FlowJo

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    Nrf2-Mediated Fibroblast Reprogramming Drives Cellular Senescence by Targeting the Matrisome
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      FlowJo

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    Bi-allelic Loss of CDKN2A Initiates Melanoma Invasion via BRN2 Activation
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      FlowJo

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    Skeletal Muscle Stem Cells from PSC-Derived Teratomas Have Functional Regenerative Capacity
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      FlowJo

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    EZH2-Mediated Primary Cilium Deconstruction Drives Metastatic Melanoma Formation
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      FlowJo

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    Gain-of-Function Mutation of Card14 Leads to Spontaneous Psoriasis-like Skin Inflammation through Enhanced Keratinocyte Response to IL-17A
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      FlowJo

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    Targeting Breast Cancer Stem Cell State Equilibrium through Modulation of Redox Signaling
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      FlowJo

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