2,458 Matching Annotations
  1. Jan 2021
  2. www.sciencedirect.com www.sciencedirect.com
    Cathepsin C promotes breast cancer lung metastasis by modulating neutrophil infiltration and neutrophil extracellular trap formation
    1
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    sciencedirect.com/science/article/pii/S1535610820306607
  3. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RNA binding RING E3-ligase DZIP3/hRUL138 stabilizes Cyclin D1 to drive cell cycle and cancer progression
    1
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      DOI: 10.1158/0008-5472.CAN-20-1871

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    ncbi.nlm.nih.gov/pmc/articles/PMC7116596/
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Visualization of stem cell activity in pancreatic cancer expansion by direct lineage tracing with live imaging
    1
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      DOI: 10.7554/eLife.55117

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    ncbi.nlm.nih.gov/pmc/articles/PMC7800378/
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pituitary stem cells produce paracrine WNT signals to control the expansion of their descendant progenitor cells
    1
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      DOI: 10.7554/eLife.59142

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    MYC regulates ribosome biogenesis and mitochondrial gene expression programs through its interaction with host cell factor–1
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      DOI: 10.7554/eLife.60191

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    elifesciences.org/articles/60191
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    Manipulation of the human tRNA pool reveals distinct tRNA sets that act in cellular proliferation or cell cycle arrest
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      DOI: 10.7554/eLife.58461

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    ncbi.nlm.nih.gov/pmc/articles/PMC7781600/
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    Induction of alarmin S100A8/A9 mediates activation of aberrant neutrophils in the pathogenesis of COVID-19
    1
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      DOI: 10.1016/j.chom.2020.12.016

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    sciencedirect.com/science/article/pii/S193131282030679X
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    Systemic Inflammation Suppresses Lymphoid Tissue Remodeling and B Cell Immunity during Concomitant Local Infection
    1
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    sciencedirect.com/science/article/pii/S2211124720315564
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    QUAKING Regulates Microexon Alternative Splicing of the Rho GTPase Pathway and Controls Microglia Homeostasis
    1
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    sciencedirect.com/science/article/pii/S2211124720315497
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    Aging-Associated Alterations in Mammary Epithelia and Stroma Revealed by Single-Cell RNA Sequencing
    1
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    sciencedirect.com/science/article/pii/S2211124720315552
  12. Dec 2020
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    B-Cell-Specific Myd88 L252P Expression Causes a Premalignant Gammopathy Resembling IgM MGUS
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC7747680/
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    Identification of a Repair-Supportive Mesenchymal Cell Population during Airway Epithelial Regeneration
    1
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    sciencedirect.com/science/article/pii/S2211124720315382
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    Exploitation of Elevated Extracellular ATP to Specifically Direct Antibody to Tumor Microenvironment
    1
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    Diet Rich in Simple Sugars Promotes Pro-Inflammatory Response via Gut Microbiota Alteration and TLR4 Signaling
    1
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      DOI: 10.3390/cells9122701

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    HIV Antibody Fc N-Linked Glycosylation Is Associated with Viral Rebound
    1
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    sciencedirect.com/science/article/pii/S2211124720314911
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    Celiac Vagus Nerve Stimulation Recapitulates Angiotensin II-Induced Splenic Noradrenergic Activation, Driving Egress of CD8 Effector Cells
    1
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    sciencedirect.com/science/article/pii/S2211124720314832
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    Heterogeneous bone-marrow stromal progenitors drive myelofibrosis via a druggable alarmin axis
    1
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    sciencedirect.com/science/article/pii/S1934590920305427
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neutrophil infiltration regulates clock-gene expression to organize daily hepatic metabolism
    1
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      DOI: 10.7554/eLife.59258

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    ncbi.nlm.nih.gov/pmc/articles/PMC7723411/
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The malaria parasite sheddase SUB2 governs host red blood cell membrane sealing at invasion
    1
    1. scibot 12 Dec 2020
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      DOI: 10.7554/eLife.61121

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  22. www.cell.com www.cell.com
    Antibody Affinity Shapes the Choice between Memory and Germinal Center B Cell Fates
    1
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      DOI: 10.1016/j.cell.2020.09.063

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    cell.com/cell/abstract/S0092-8674(20)31304-0
  23. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Identification of tumor‐associated macrophage subsets that are associated with breast cancer prognosis
    1
    1. scibot 11 Dec 2020
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      DOI: 10.1002/ctm2.239

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    onlinelibrary.wiley.com/doi/full/10.1002/ctm2.239
  24. link.springer.com link.springer.com
    GD2 or HER2 targeting T cell engaging bispecific antibodies to treat osteosarcoma
    1
    1. scibot 11 Dec 2020
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      DOI: 10.1186/s13045-020-01012-y

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    link.springer.com/article/10.1186/s13045-020-01012-y
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Baricitinib treatment resolves lower-airway macrophage inflammation and neutrophil recruitment in SARS-CoV-2-infected rhesus macaques
    1
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      DOI: 10.1016/j.cell.2020.11.007

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  26. elifesciences.org elifesciences.org
    BAD inactivation exacerbates rheumatoid arthritis pathology by promoting survival of sublining macrophages
    1
    1. scibot 09 Dec 2020
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      DOI: 10.7554/eLife.56309

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  27. elifesciences.org elifesciences.org
    Concerted action of kinesins KIF5B and KIF13B promotes efficient secretory vesicle transport to microtubule plus ends
    1
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      DOI: 10.7554/eLife.61302

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  28. elifesciences.org elifesciences.org
    RNF41 regulates the damage recognition receptor Clec9A and antigen cross-presentation in mouse dendritic cells
    1
    1. scibot 09 Dec 2020
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      DOI: 10.7554/eLife.63452

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  29. www.sciencedirect.com www.sciencedirect.com
    High throughput profiling of undifferentiated pleomorphic sarcomas identifies two main subgroups with distinct immune profile, clinical outcome and sensitivity to targeted therapies
    1
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      DOI: 10.1016/j.ebiom.2020.103131

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    Multiple Alternative Promoters and Alternative Splicing Enable Universal Transcription-Based Logic Computation in Mammalian Cells
    1
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    sciencedirect.com/science/article/pii/S2211124720314261
  31. link.springer.com link.springer.com
    Melanoma cells can be eliminated by sialylated CD43 × CD3 bispecific T cell engager formats in vitro and in vivo
    1
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      DOI: 10.1007/s00262-020-02780-9

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  32. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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      DOI: 10.1111/bph.15216

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15216
  33. Nov 2020
  34. elifesciences.org elifesciences.org
    MicroRNAs of the miR-17~9 family maintain adipose tissue macrophage homeostasis by sustaining IL-10 expression
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      DOI: 10.7554/eLife.55676

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    JAK1 Inhibition Blocks Lethal Immune Hypersensitivity in a Mouse Model of Down Syndrome
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    sciencedirect.com/science/article/pii/S2211124720313966
  36. www.nature.com www.nature.com
    Calciprotein particle-induced cytotoxicity via lysosomal dysfunction and altered cholesterol distribution in renal epithelial HK-2 cells
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      DOI: 10.1038/s41598-020-77308-3

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  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The RIF1-long splice variant promotes G1 phase 53BP1 nuclear bodies to protect against replication stress
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      DOI: 10.7554/eLife.58020

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  38. www.sciencedirect.com www.sciencedirect.com
    Isolation of Human CD49f+ Astrocytes and In Vitro iPSC-Based Neurotoxicity Assays
    1
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      DOI: 10.1016/j.xpro.2020.100172

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    sciencedirect.com/science/article/pii/S2666166720301593
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Macrophages promote endothelial-to-mesenchymal transition via MT1-MMP/TGFβ1 after myocardial infarction
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      DOI: 10.7554/eLife.57920

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    ncbi.nlm.nih.gov/pmc/articles/PMC7609061/
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    Metabolic Reprogramming Induces Germinal Center B Cell Differentiation through Bcl6 Locus Remodeling
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      DOI: 10.1016/j.celrep.2020.108333

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    Microglial Displacement of GABAergic Synapses Is a Protective Event during Complex Febrile Seizures
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      DOI: 10.1016/j.celrep.2020.108346

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    sciencedirect.com/science/article/pii/S2211124720313358
  42. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Airway Microbiota-Host Interactions Regulate Secretory Leukocyte Protease Inhibitor Levels and Influence Allergic Airway Inflammation
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      DOI: 10.1016/j.celrep.2020.108331

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  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BPS Publications
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      DOI: 10.1111/bph.15237

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  44. Oct 2020
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    TET2-Loss-of-Function-Driven Clonal Hematopoiesis Exacerbates Experimental Insulin Resistance in Aging and Obesity
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    HLA-DR15 Molecules Jointly Shape an Autoreactive T Cell Repertoire in Multiple Sclerosis
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    CD103+CD8+ TRM Cells Accumulate in Tumors of Anti-PD-1-Responder Lung Cancer Patients and Are Tumor-Reactive Lymphocytes Enriched with Tc17
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    PPARα Inhibition Overcomes Tumor-Derived Exosomal Lipid-Induced Dendritic Cell Dysfunction
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    Antibody Feedback Limits the Expansion of B Cell Responses to Malaria Vaccination but Drives Diversification of the Humoral Response
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    Continued Bcl6 Expression Prevents the Transdifferentiation of Established Tfh Cells into Th1 Cells during Acute Viral Infection
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    Postprandial Hypoglycemia in Patients after Gastric Bypass Surgery Is Mediated by Glucose-Induced IL-1β
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    Bone Marrow Mesenchymal Stem Cells Support Acute Myeloid Leukemia Bioenergetics and Enhance Antioxidant Defense and Escape from Chemotherapy
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    Dendritic Cell Paucity Leads to Dysfunctional Immune Surveillance in Pancreatic Cancer
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    Analysis of a Therapeutic Antibody Cocktail Reveals Determinants for Cooperative and Broad Ebolavirus Neutralization
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    Metabolic Insights Into Infochemicals Induced Colony Formation and Flocculation in Scenedesmus subspicatus Unraveled by Quantitative Proteomics
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    Genome-Scale CRISPR Screening in Human Intestinal Organoids Identifies Drivers of TGF-β Resistance
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    Regulatory Dynamics of Tet1 and Oct4 Resolve Stages of Global DNA Demethylation and Transcriptomic Changes in Reprogramming
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    Medulloblastoma Arises from the Persistence of a Rare and Transient Sox2+ Granule Neuron Precursor
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    Injury Delays Stem Cell Apoptosis after Radiation in Planarians
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    A human ESC-based screen identifies a role for the translated lncRNA LINC00261 in pancreatic endocrine differentiation
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    Allosteric Activators of Protein Phosphatase 2A Display Broad Antitumor Activity Mediated by Dephosphorylation of MYBL2
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    TBC1D5-Catalyzed Cycling of Rab7 Is Required for Retromer-Mediated Human Papillomavirus Trafficking during Virus Entry
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    LIN28B Underlies the Pathogenesis of a Subclass of Ewing Sarcoma LIN28B Control of EWS-FLI1 Stability
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    Route of Vaccine Administration Alters Antigen Trafficking but Not Innate or Adaptive Immunity
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    CXCR4 Signaling Has a CXCL12-Independent Essential Role in Murine MLL-AF9-Driven Acute Myeloid Leukemia
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    Sialyl-LewisX Glycoantigen Is Enriched on Cells with Persistent HIV Transcription during Therapy
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    Virus infection is controlled by hematopoietic and stromal cell sensing of murine cytomegalovirus through STING
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    A Single Human VH-gene Allows for a Broad-Spectrum Antibody Response Targeting Bacterial Lipopolysaccharides in the Blood
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    A Susceptibility Locus on Chromosome 13 Profoundly Impacts the Stability of Genomic Imprinting in Mouse Pluripotent Stem Cells
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    Characterization of Resident Corneal Plasmacytoid Dendritic Cells and Their Pivotal Role in Herpes Simplex Keratitis
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    Non-neutralizing Antibodies from a Marburg Infection Survivor Mediate Protection by Fc-Effector Functions and by Enhancing Efficacy of Other Antibodies
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    A Deregulated HOX Gene Axis Confers an Epigenetic Vulnerability in KRAS-Mutant Lung Cancers
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    Symmetric Arginine Dimethylation Is Selectively Required for mRNA Splicing and the Initiation of Type I and Type III Interferon Signaling
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    Imprinted Maternally Expressed microRNAs Antagonize Paternally Driven Gene Programs in Neurons
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    The Amount of BCL6 in B Cells Shortly after Antigen Engagement Determines Their Representation in Subsequent Germinal Centers
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    Chronic Viral Infection Promotes Efficient Germinal Center B Cell Responses
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    Malignant Transformation Involving CXXC4 Mutations Identified in a Leukemic Progression Model of Severe Congenital Neutropenia
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    Microfold cell-dependent antigen transport alleviates infectious colitis by inducing antigen-specific cellular immunity
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    Differentiation Paths of Peyer’s Patch LysoDCs Are Linked to Sampling Site Positioning, Migration, and T Cell Priming
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    Topological Adaptation of Transmembrane Domains to the Force-Modulated Lipid Bilayer Is a Basis of Sensing Mechanical Force
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    Cerebrovascular amyloid Angiopathy in bioengineered vessels is reduced by high-density lipoprotein particles enriched in Apolipoprotein E
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    Salmonella Typhoid Toxin PltB Subunit and Its Non-typhoidal Salmonella Ortholog Confer Differential Host Adaptation and Virulence
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    An Integrated Gene Expression Landscape Profiling Approach to Identify Lung Tumor Endothelial Cell Heterogeneity and Angiogenic Candidates
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  168. Jan 2020
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    NHEJ-Mediated Repair of CRISPR-Cas9-Induced DNA Breaks Efficiently Corrects Mutations in HSPCs from Patients with Fanconi Anemia
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    Toxoplasma gondii infection drives conversion of NK cells into ILC1-like cells
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    β-Glucan-Induced Trained Immunity Protects against Leishmania braziliensis Infection: a Crucial Role for IL-32
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    Stereotactic Body Radiation and Interleukin-12 Combination Therapy Eradicates Pancreatic Tumors by Repolarizing the Immune Microenvironment
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    Programming of Distinct Chemokine-Dependent and -Independent Search Strategies for Th1 and Th2 Cells Optimizes Function at Inflamed Sites
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    Molecular Profiling and Functional Analysis of Macrophage-Derived Tumor Extracellular Vesicles
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    Human perivascular stem cell-derived extracellular vesicles mediate bone repair
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    IL-12 Blocks Tfh Cell Differentiation during Salmonella Infection, thereby Contributing to Germinal Center Suppression
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    Optimization-by-design of hepatotropic lipid nanoparticles targeting the sodium-taurocholate cotransporting polypeptide
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    TLR9 agonist MGN1703 enhances B cell differentiation and function in lymph nodes
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    The Transcription Factor Tox2 Drives T Follicular Helper Cell Development via Regulating Chromatin Accessibility
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    Gene-centric functional dissection of human genetic variation uncovers regulators of hematopoiesis
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    Therapy with multi-epitope virus-like particles of B19 parvovirus reduce tumor growth and lung metastasis in an aggressive breast cancer mouse model
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    Metformin Restores CNS Remyelination Capacity by Rejuvenating Aged Stem Cells
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    Restricted Clonality and Limited Germinal Center Reentry Characterize Memory B Cell Reactivation by Boosting
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    Mechanisms of Progression of Myeloid Preleukemia to Transformed Myeloid Leukemia in Children with Down Syndrome
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    The Hippo Pathway Effector TAZ Regulates Ferroptosis in Renal Cell Carcinoma
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    Effect of early-stage autophagy inhibition in BRAF V600E autophagy-dependent brain tumor cells
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    The Histone Methyltransferase Setdb2 Modulates Macrophage Phenotype and Uric Acid Production in Diabetic Wound Repair
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    TCR- or Cytokine-Activated CD8+ Mucosal-Associated Invariant T Cells Are Rapid Polyfunctional Effectors That Can Coordinate Immune Responses
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  190. elifesciences.org elifesciences.org
    Replication Study: Wnt activity defines colon cancer stem cells and is regulated by the microenvironment
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      DOI: 10.7554/eLife.45426

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    N6-Isopentenyladenosine Inhibits Colorectal Cancer and Improves Sensitivity to 5-Fluorouracil-Targeting FBXW7 Tumor Suppressor
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    eIF4A supports an oncogenic translation program in pancreatic ductal adenocarcinoma
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      DOI: 10.1038/s41467-019-13086-5

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    Germline-Encoded Affinity for Cognate Antigen Enables Vaccine Amplification of a Human Broadly Neutralizing Response against Influenza Virus
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    T Cell Repertoire Dynamics during Pregnancy in Multiple Sclerosis
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    Fasting-Refeeding Impacts Immune Cell Dynamics and Mucosal Immune Responses
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    PCNA Unloading Is Negatively Regulated by BET Proteins
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    Metabolite-Sensing Receptor Ffar2 Regulates Colonic Group 3 Innate Lymphoid Cells and Gut Immunity
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    Oncogenic MYC amplifies mitotic perturbations
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    FMRP Modulates Neural Differentiation through m6A-Dependent mRNA Nuclear Export
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    Genome-wide Analyses of Chromatin State in Human Mast Cells Reveal Molecular Drivers and Mediators of Allergic and Inflammatory Diseases
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    NIX-Mediated Mitophagy Promotes Effector Memory Formation in Antigen-Specific CD8+ T Cells
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    Robust Iterative Stimulation with Self-Antigens Overcomes CD8+ T Cell Tolerance to Self- and Tumor Antigens
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    High Glucose Intake Exacerbates Autoimmunity through Reactive-Oxygen-Species-Mediated TGF-β Cytokine Activation
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    DUX4 Suppresses MHC Class I to Promote Cancer Immune Evasion and Resistance to Checkpoint Blockade
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      DOI: 10.1016/j.devcel.2019.06.011

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    The quantity of CD40 signaling determines the differentiation of B cells into functionally distinct memory cell subsets
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      RRID:SCR_008520

      DOI: 10.7554/eLife.44245

      Resource: FlowJo (RRID:SCR_008520)

      Curator: @Naa003

      SciCrunch record: RRID:SCR_008520

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      RRID:SCR_008520 RRIDCUR:Validated
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    elifesciences.org/articles/44245
  207. www.frontiersin.org www.frontiersin.org
    Enhanced Immunomodulation in Inflammatory Environments Favors Human Cardiac Mesenchymal Stromal-Like Cells for Allogeneic Cell Therapies
    1
    1. scibot 13 Jan 2020
      RRID:SCR_008520

      DOI: 10.3389/fimmu.2019.01716

      Resource: FlowJo (RRID:SCR_008520)

      Curator: @Naa003

      SciCrunch record: RRID:SCR_008520

      What is this?

      RRID:SCR_008520 RRIDCUR:Validated
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    frontiersin.org/articles/10.3389/fimmu.2019.01716/full