3,394 Matching Annotations
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    Defining the functional role and potential as an immunotherapeutic target of ALCAM in neuroblastoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12729689/
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    MIF-Induced CD74+ Microglia and Macrophages Promote Progression of Brain Metastasis and are Clinically Relevant Across Central Nervous System Disorders
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    pmc.ncbi.nlm.nih.gov/articles/PMC7618953/
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    A Novel Anti-CD47 Antibody TJH2201: Efficacious Tumor Suppression with Reduced RBC Toxicity via a SIRPα-Independent Mechanism
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    aacrjournals.org/mct/article/25/1/21/771288/A-Novel-Anti-CD47-Antibody-TJH2201-Efficacious
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    TUB-040, a Homogeneous and Hydrophilic NaPi2b-Targeting ADC with Stably Linked Exatecan, Exhibits Long-lasting Antitumor Activity and a Well-Tolerated Safety Profile
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    aacrjournals.org/mct/article/24/11/1685/766863/TUB-040-a-Homogeneous-and-Hydrophilic-NaPi2b
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    The recycling collagen receptor uPARAP is a unique mediator of stromal drug delivery to carcinoma cells
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    Harnessing senolytics and PARP inhibition to expand the antitumor activity of CDK4/6 inhibitors in prostate cancer
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    aacrjournals.org/mct/article/24/12/1959/768323/Harnessing-Senolytics-and-PARP-Inhibition-to
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    Sialic acid cis-ligand dynamics modulate Siglec-7 and -9 function and affect Siglec-7/9 co-blockade to potentiate natural killer cell anti-tumor activity
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    AXL–SHC1 signaling axis mediates adaptive resistance to HER2-targeted tyrosine kinase inhibitors in HER2-aberrant lung and gastric cancers
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    nature.com/articles/s41698-026-01385-2
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    Astragaloside IV directly targets PPP1R14B to sensitize prostate cancer to anti-PD-1 immunotherapy by remodeling the CX3CL1/CD8+ T cell axis
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    A dual-reporter mouse for therapeutic discovery in Angelman syndrome
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    Schlafen 5 is an intracellular immune checkpoint and controls interferon responses in pancreatic ductal adenocarcinoma
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    YAP1 Dysfunction Promotes Molecular Properties Linked to Breast Cancer Susceptibility
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    αvβ3 CAR-T Cells Simultaneously Targeting Tumor and Metastases Produce Highly Effective Control in Preclinical Models of Melanoma and Triple-Negative Breast Cancer
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    AURKA-mediated destabilization of SAPS3 drives ferroptosis evasion via 7-dehydrocholesterol biosynthesis in colorectal cancer
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    Co-Targeting Bcl-xL with Mcl-1 Induces Lethal Mitochondrial Dysfunction in Diffuse Mesothelioma
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    aacrjournals.org/mct/article/24/10/1640/765491/Co-Targeting-BCL-xL-with-MCL-1-Induces-Lethal
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    Integrating interferon gamma receptor pathways, antigenicity, and immune contexture as predictors of immunotherapeutic strategies for mucosal melanomas
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    Comparing Heparin and Heparin Mimetics in Targeting Immunomodulatory Proteins from Platelets to Activate T Cell-Dependent Immune Response in Oncology
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    pubs.acs.org/doi/10.1021/acsptsci.5c00722
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    Sulfur partitioning from cysteine controls T cell proliferation and effector function
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  23. Apr 2026
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    Refractory infantile IPEX with Treg-restricted FOXP3null expression caused by a novel variant in FOXP3
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    The aryl hydrocarbon receptor (AHR) drives human leukocyte antigen (HLA)-II expression in human melanoma
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    Loss of miR-29a/b1 cluster reprograms the tumor microenvironment and contributes to immunosuppression in lung cancer
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    Penicillide Triggers Immunogenic Pyroptosis in Tumor Cells via Oxidative Stress/NF-κB/GSDMD Signaling Axis
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  28. Mar 2026
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    Perinatal infection elicits clonally restricted T follicular helper cell responses that drive antibody-mediated viral control
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    Tuft cells promote reactivation of memory Th2 cells and are required for protective immunity to intestinal helminth re-infection
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    Rapid expansion of primary human vocal fold epithelial cells via targeted pathway inhibition and anchorage-independent sphere culture
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    Regulatory T cell-derived TGF-β signaling governs the differentiation and maintenance of tumor-infiltrating bystander CD8+ T cells
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    Targeting systemic and tumor metabolic balances with ketogenic diets enhance efficacy of therapy in FLT3-ITD acute myeloid leukemia
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    E2A selectively regulates TGF-β–induced apoptosis in KRAS-mutant non-small cell lung cancer
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    Baseline tumor features and systemic immune dynamics underlying efficacy in MSS metastatic colorectal cancer treated with regorafenib, ipilimumab, and nivolumab
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    Association of Circulating T Cell and Tumor Microenvironment Profiles with Immune Checkpoint Blockade Outcome in Sarcoma
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    Myofibroblast programming blocks differentiation of TLS-organizing fibroblastic reticular cells in pancreatic cancer
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    Immunological effects of amivantamab in EGFR or MET-expressing non-small cell lung cancer
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    Nanobody-Engineered CLL-1 CAR-T Cells: Optimizing Tumor-Specific Cytotoxicity and Minimizing Off-Tumor Toxicity
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    Collagen-bearing exosomes from breast cancer-associated fibroblasts promote T cell dysfunction
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    Microglia Display Heterogeneous Initial Responses to Disseminated Tumor Cells
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    YTHDF3 facilitates DNA damage response by recognizing METTL3-mediated m6A modification to promote chemotherapy resistance in glioblastoma
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    Blocking SHP2 benefits FGFR2 inhibitor and overcomes its resistance in FGFR2-amplified gastric cancer
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    Pregnancy-associated metabolic adaptations in circulating monocytes and macrophages favor clearance functions
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    Protocol to annotate dendritic cell maturation types in vivo making use of lipid nanoparticle-based approaches
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    Human pluripotent stem cell-derived atrioventricular node-like pacemaker cells exhibit biological conduction bridge properties
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    Metabolite-induced DNA damage drives stochastic stem cell loss and clonal hematopoiesis
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    Multiomic analysis of ART-interruption cohorts identifies cell-extrinsic and -intrinsic mechanisms driving lymphocyte-mediated control of HIV rebound
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    Aging disrupts sympathetic innervation of the thymus
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    Radiotherapy synergizes with an inducible AAV-based immunotherapy platform to program local and systemic antitumor immunity
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    7,7”-dimethoxyagastisflavone induced MYCN/MYBL2-dependent apoptosis and metabolism reprogramming in Sonic Hedgehog medulloblastoma
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    CD38 degrades MAVS through mitophagy to inhibit type I interferon secretion in nasopharyngeal carcinoma cells and impairs CD8+T cell-mediated anti-tumor immunity
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    Cancer cell-derived sialylated IgG interacting with Siglec-7/9/10 is a potential immunotherapeutic target in pancreatic cancer
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    6-Hydroxydopamine promotes antitumor immunity through macrophage remodeling beyond sympathetic ablation
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    PRMT5 is Frequently Upregulated and a Potential Therapeutic Target in MTAP-deficient Malignant Peripheral Nerve Sheath Tumors
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    Prednisolone modulates CD8⁺ and regulatory T-cell activity to dampen response to immune checkpoint inhibitor therapy in melanoma
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    A developmentally regulated long-range enhancer-promoter contact mediates human neural development
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    Combining lenalidomide with IL-2 family of cytokines enhances activating receptor and perforin/granzyme expression in NK cells
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    Medium-Chain Fatty Acid Receptor GPR84 Modulates Cytotoxic CD8 T cells Antitumor Immunity Through Metabolic Reprogramming
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    Kindlin-2-mediated hematopoiesis remodeling regulates triple-negative breast cancer immune evasion
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    NN-01-195, a novel conjugate of HSP90 and AURKA inhibitors, effectively targets solid tumors
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    Differential sensitivity of leukocyte populations to Staphylococcus aureus biofilm
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    Prednisolone modulates CD8⁺ and regulatory T-cell activity to dampen response to immune checkpoint inhibitor therapy in melanoma
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    Cell type-specific epigenetic regulatory circuitry of coronary artery disease loci
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    Protein-level profiling of TIGIT axis components in human PDAC reveals immune–suppressive expression patterns
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    The presence of CD11c+ B cells with potent effector memory phenotype in lung adenocarcinoma correlates with overall patient survival
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    Targeting pre-existing club-like cells in prostate cancer potentiates androgen deprivation therapy
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    Aerobic sister lineage of breviates has gene-rich mitochondrial genomes
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    TCR-NF-κB signaling activates the SENP1-NR4A1 axis to fine-tune effector activation of CD8+ T cells
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    Mitochondrial transfer to granulocytic myeloid-derived suppressor cells augments immunosuppressive activity
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    Intratumoral microbiota and host genotype cooperatively shape neutrophil cytotoxic functions in colorectal cancer
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    DNA polymerase μ protects macrophages from DNA damage produced during pro-inflammatory activation
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    Pluripotent stem-cell-based screening uncovers sildenafil as a mitochondrial disease therapy
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    Ectopic CD11c Drives SMAD3-Mediated Aberrant Antigen Presentation and Epithelial–Mesenchymal Transition in Esophageal Squamous Cell Carcinoma
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    Ex Vivo Immuno-Oncology Platform Reveals Spatial T Cell Infiltration Patterns Linked to ATR Inhibition Responses in High-Grade Serous Ovarian Cancer
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    Up-regulation of an epithelial miRNA is associated with immune evasion in progressive bronchial premalignant lesions
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