2,154 Matching Annotations
  1. Dec 2020
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-scale CRISPR screening at high sensitivity with an empirically designed sgRNA library
    1
    1. scibot 07 Dec 2020
      Addgene_12259

      DOI: 10.1186/s12915-020-00905-1

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    ncbi.nlm.nih.gov/pmc/articles/PMC7686728/
  3. Nov 2020
  4. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Requisite Chromatin Remodeling for Myeloid and Erythroid Lineage Differentiation from Erythromyeloid Progenitors
    2
    1. scibot 25 Nov 2020
      RRID:Addgene_12259

      DOI: 10.1016/j.celrep.2020.108395

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      RRID:Addgene_12259
    2. scibot 25 Nov 2020
      plasmid_12259

      DOI: 10.1016/j.celrep.2020.108395

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      RRIDCUR:Validated RRID:Addgene_12259
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    pubmed.ncbi.nlm.nih.gov/33207205/
  5. www.nature.com www.nature.com
    Raloxifene prevents stress granule dissolution, impairs translational control and promotes cell death during hypoxia in glioblastoma cells
    1
    1. scibot 24 Nov 2020
      plasmid_12259

      DOI: 10.1038/s41419-020-03159-5

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    nature.com/articles/s41419-020-03159-5
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Homology-guided identification of a conserved motif linking the antiviral functions of IFITM3 to its oligomeric state
    1
    1. scibot 22 Nov 2020
      RRID:Addgene_12259

      DOI: 10.7554/eLife.58537

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    ncbi.nlm.nih.gov/pmc/articles/PMC7665892/
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cytotoxic T cells swarm by homotypic chemokine signalling
    1
    1. scibot 21 Nov 2020
      RRID:Addgene_12259

      DOI: 10.7554/eLife.56554

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    ncbi.nlm.nih.gov/pmc/articles/PMC7669268/
  8. www.sciencedirect.com www.sciencedirect.com
    PICK1 Controls Activity-Dependent Synaptic Vesicle Cargo Retrieval
    1
    1. scibot 05 Nov 2020
      Plasmid_12259

      DOI: 10.1016/j.celrep.2020.108312

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    sciencedirect.com/science/article/pii/S2211124720313012
  9. Oct 2020
  10. www.sciencedirect.com www.sciencedirect.com
    SARS-CoV-2 Infects the Brain Choroid Plexus and Disrupts the Blood-CSF Barrier in Human Brain Organoids
    1
    1. scibot 31 Oct 2020
      plasmid_12259

      DOI: 10.1016/j.stem.2020.10.001

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    sciencedirect.com/science/article/pii/S1934590920304951
  11. www.sciencedirect.com www.sciencedirect.com
    IL4I1 Is a Metabolic Immune Checkpoint that Activates the AHR and Promotes Tumor Progression
    1
    1. scibot 31 Oct 2020
      plasmid_12259

      DOI: 10.1016/j.cell.2020.07.038

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    sciencedirect.com/science/article/pii/S0092867420309466
  12. www.sciencedirect.com www.sciencedirect.com
    PPARα Inhibition Overcomes Tumor-Derived Exosomal Lipid-Induced Dendritic Cell Dysfunction
    1
    1. scibot 27 Oct 2020
      pMD2.G

      DOI: 10.1016/j.celrep.2020.108278

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    sciencedirect.com/science/article/pii/S2211124720312675
  13. elifesciences.org elifesciences.org
    Light-regulated allosteric switch enables temporal and subcellular control of enzyme activity
    1
    1. scibot 27 Oct 2020
      RRID:Addgene_12259

      DOI: 10.7554/eLife.60647

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    elifesciences.org/articles/60647
  14. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Schwannoma development is mediated by Hippo pathway dysregulation and modified by RAS/MAPK signaling
    1
    1. scibot 22 Oct 2020
      RRID:Addgene_12259

      DOI: 10.1172/jci.insight.141514

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    pubmed.ncbi.nlm.nih.gov/32960816/
  15. www.embopress.org www.embopress.org
    Identification of a dynamic gene regulatory network required for pluripotency factor‐induced reprogramming of mouse fibroblasts and hepatocytes
    1
    1. scibot 13 Oct 2020
      RRID:Addgene_12259

      DOI: 10.15252/embj.2019102236

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    embopress.org/doi/full/10.15252/embj.2019102236
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Collagen-rich omentum is a premetastatic niche for integrin α2-mediated peritoneal metastasis
    1
    1. scibot 13 Oct 2020
      RRID:Addgene_12259

      DOI: 10.7554/eLife.59442

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    ncbi.nlm.nih.gov/pmc/articles/PMC7541088/
  17. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Respiratory Supercomplexes Promote Mitochondrial Efficiency and Growth in Severely Hypoxic Pancreatic Cancer
    1
    1. scibot 08 Oct 2020
      RRID:Addgene_12259

      DOI: 10.1016/j.celrep.2020.108231

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    pubmed.ncbi.nlm.nih.gov/33027658/
  18. www.sciencedirect.com www.sciencedirect.com
    MED19 Regulates Adipogenesis and Maintenance of White Adipose Tissue Mass by Mediating PPARγ-Dependent Gene Expression
    1
    1. scibot 07 Oct 2020
      pMD2.G

      DOI: 10.1016/j.celrep.2020.108228

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      RRID:Addgene_12259 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S2211124720312171
  19. www.sciencedirect.com www.sciencedirect.com
    MYC Promotes Bone Marrow Stem Cell Dysfunction in Fanconi Anemia
    1
    1. scibot 01 Oct 2020
      pMD2.G plasmid

      DOI: 10.1016/j.stem.2020.09.004

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      RRIDCUR:Missing RRID:Addgene_12259
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    sciencedirect.com/science/article/pii/S1934590920304501
  20. Sep 2020
  21. www.sciencedirect.com www.sciencedirect.com
    Activation of CpG-Rich Promoters Mediated by MLL Drives MOZ-Rearranged Leukemia
    1
    1. scibot 30 Sep 2020
      Plasmid_12259

      DOI: 10.1016/j.celrep.2020.108200

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    sciencedirect.com/science/article/pii/S221112472031189X
  22. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Single point mutations within the Coxsackie B virus receptor-binding site promote resistance against soluble virus receptor traps
    1
    1. scibot 26 Sep 2020
      RRID Addgene 12259

      DOI: 10.1128/JVI.00952-20

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    pubmed.ncbi.nlm.nih.gov/32669334/
  23. www.sciencedirect.com www.sciencedirect.com
    Immune Sensing of Synthetic, Bacterial, and Protozoan RNA by Toll-like Receptor 8 Requires Coordinated Processing by RNase T2 and RNase 2
    1
    1. scibot 26 Sep 2020
      RRID:Addgene_12259

      DOI: 10.1016/j.immuni.2020.03.009

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    sciencedirect.com/science/article/pii/S1074761320301229
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Perturbation of base excision repair sensitizes breast cancer cells to APOBEC3 deaminase-mediated mutations
    1
    1. scibot 26 Sep 2020
      RRID:Addgene_12259

      DOI: 10.7554/eLife.51605

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    ncbi.nlm.nih.gov/pmc/articles/PMC6961979/
  25. www.sciencedirect.com www.sciencedirect.com
    Caspase-6 Is a Key Regulator of Innate Immunity, Inflammasome Activation, and Host Defense
    1
    1. scibot 26 Sep 2020
      RRID:Addgene_12259

      DOI: 10.1016/j.cell.2020.03.040

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    sciencedirect.com/science/article/pii/S0092867420303330
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SARS-CoV-2 Infection Depends on Cellular Heparan Sulfate and ACE2
    1
    1. scibot 26 Sep 2020
      plasmid_12259

      DOI: 10.1016/j.cell.2020.09.033

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    ncbi.nlm.nih.gov/pmc/articles/PMC7489987/
  27. www.sciencedirect.com www.sciencedirect.com
    A drug screening toolkit based on the –1 ribosomal frameshifting of SARS-CoV-2
    1
    1. scibot 25 Sep 2020
      RRID:Addgene_12259

      DOI: 10.1016/j.heliyon.2020.e04793

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    sciencedirect.com/science/article/pii/S2405844020316364
  28. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Mutational resilience of antiviral restriction favors primate TRIM5α in host-virus evolutionary arms races
    2
    1. scibot 23 Sep 2020
      MD2.G

      DOI: 10.7554/eLife.59988

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      Curator: @evieth

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      RRIDCUR:Missing RRID:Addgene_12259
    2. scibot 22 Sep 2020
      plasmid_12259

      DOI: 10.7554/eLife.59988

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    pubmed.ncbi.nlm.nih.gov/32930662/
  29. www.sciencedirect.com www.sciencedirect.com
    RAI1 Regulates Activity-Dependent Nascent Transcription and Synaptic Scaling
    1
    1. scibot 23 Sep 2020
      RRID:Addgene_12259

      DOI: 10.1016/j.celrep.2020.108002

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    sciencedirect.com/science/article/pii/S2211124720309876
  30. journals.plos.org journals.plos.org
    TRIM34 restricts HIV-1 and SIV capsids in a TRIM5α-dependent manner
    1
    1. scibot 23 Sep 2020
      Addgene_12259

      DOI: 10.1371/journal.ppat.1008507

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    journals.plos.org/plospathogens/article
  31. rupress.org rupress.org
    GRAF2, WDR44, and MICAL1 mediate Rab8/10/11–dependent export of E-cadherin, MMP14, and CFTR ΔF508
    1
    1. scibot 23 Sep 2020
      RRID:Addgene_12259

      DOI: 10.1083/jcb.201811014

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    rupress.org/jcb/article/219/5/e201811014/151714/GRAF2-WDR44-and-MICAL1-mediate-Rab8-10-11
  32. www.frontiersin.org www.frontiersin.org
    A20 Restricts Inflammatory Response and Desensitizes Gingival Keratinocytes to Apoptosis
    1
    1. scibot 17 Sep 2020
      RRID:Addgene_12259

      DOI: 10.3389/fimmu.2020.00365

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    frontiersin.org/article/10.3389/fimmu.2020.00365/full
  33. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Malignant Transformation Involving CXXC4 Mutations Identified in a Leukemic Progression Model of Severe Congenital Neutropenia
    1
    1. scibot 17 Sep 2020
      RRID:Addgene_12259

      DOI: 10.1016/j.xcrm.2020.100074

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    pubmed.ncbi.nlm.nih.gov/33205068/
  34. elifesciences.org elifesciences.org
    Modulation of dopamine D1 receptors via histamine H3 receptors is a novel therapeutic target for Huntington's disease
    1
    1. scibot 17 Sep 2020
      Addgene_12259

      DOI: 10.7554/eLife.51093

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    elifesciences.org/articles/51093
  35. www.sciencedirect.com www.sciencedirect.com
    An Evolutionary Insertion in the Mxra8 Receptor-Binding Site Confers Resistance to Alphavirus Infection and Pathogenesis
    1
    1. scibot 16 Sep 2020
      RRID:Addgene_12259

      DOI: 10.1016/j.chom.2020.01.008

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    sciencedirect.com/science/article/pii/S1931312820300470
  36. elifesciences.org elifesciences.org
    A human ESC-based screen identifies a role for the translated lncRNA LINC00261 in pancreatic endocrine differentiation
    1
    1. scibot 16 Sep 2020
      RRID:Addgene_12259

      DOI: 10.7554/eLife.58659

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    elifesciences.org/articles/58659
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Proteasome inhibitor-induced modulation reveals the spliceosome as a specific therapeutic vulnerability in multiple myeloma
    1
    1. scibot 16 Sep 2020
      Plasmid_12259

      DOI: 10.1038/s41467-020-15521-4

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    ncbi.nlm.nih.gov/pmc/articles/PMC7176739/
  38. www.sciencedirect.com www.sciencedirect.com
    Super-Enhancer Redistribution as a Mechanism of Broad Gene Dysregulation in Repeatedly Drug-Treated Cancer Cells
    2
    1. scibot 16 Sep 2020
      RRID:Addgene_12259

      DOI: 10.1016/j.celrep.2020.107532

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      RRIDCUR:Validated RRID:Addgene_12259
    2. scibot 03 Sep 2020
      RRID:Addgene_12259

      DOI: 10.1016/j.celrep.2020.107532

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    sciencedirect.com/science/article/pii/S2211124720304320
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    YAP regulates cell size and growth dynamics via non-cell autonomous mediators
    1
    1. scibot 16 Sep 2020
      RRID:Addgene_12259

      DOI: 10.7554/eLife.53404

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    ncbi.nlm.nih.gov/pmc/articles/PMC6989120/
  40. link.springer.com link.springer.com
    Impaired differentiation of human induced neural stem cells by TOR1A overexpression
    1
    1. scibot 16 Sep 2020
      RRID:Addgene_12259

      DOI: 10.1007/s11033-020-05390-x

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    link.springer.com/article/10.1007/s11033-020-05390-x
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    High-Throughput, Temporal and Dose Dependent, Effect of Vitamins and Minerals on Chondrogenesis
    1
    1. scibot 15 Sep 2020
      RRID:Addgene_12259

      DOI: 10.3389/fcell.2020.00092

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    ncbi.nlm.nih.gov/pmc/articles/PMC7053227/
  42. www.mdpi.com www.mdpi.com
    Isolation of Human Small Extracellular Vesicles and Tracking of their Uptake by Retinal Pigment Epithelial Cells In Vitro
    1
    1. scibot 15 Sep 2020
      RRID:Addgene_12259

      DOI: 10.3390/ijms21113799

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    mdpi.com/1422-0067/21/11/3799
  43. www.nature.com www.nature.com
    Locoregional delivery of CAR T cells to the cerebrospinal fluid for treatment of metastatic medulloblastoma and ependymoma
    1
    1. scibot 15 Sep 2020
      RRID:Addgene_12259

      DOI: 10.1038/s41591-020-0827-2

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    nature.com/articles/s41591-020-0827-2
  44. www.sciencedirect.com www.sciencedirect.com
    SIX2 Regulates Human β Cell Differentiation from Stem Cells and Functional Maturation In Vitro
    1
    1. scibot 14 Sep 2020
      RRID:Addgene_12259

      DOI: 10.1016/j.celrep.2020.107687

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    Phenotypic Screen with TSC-Deficient Neurons Reveals Heat-Shock Machinery as a Druggable Pathway for mTORC1 and Reduced Cilia
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    Genome-wide Screens Implicate Loss of Cullin Ring Ligase 3 in Persistent Proliferation and Genome Instability in TP53-Deficient Cells
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    Mitochondrial DNA mutations induce mitochondrial biogenesis and increase the tumorigenic potential of Hodgkin and Reed-Sternberg cells
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  48. www.sciencedirect.com www.sciencedirect.com
    Comprehensive Molecular Characterization Identifies Distinct Genomic and Immune Hallmarks of Renal Medullary Carcinoma
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    Low-Dose Sorafenib Acts as a Mitochondrial Uncoupler and Ameliorates Nonalcoholic Steatohepatitis
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    Bacteria Boost Mammalian Host NAD Metabolism by Engaging the Deamidated Biosynthesis Pathway
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    Zika Virus Targets Glioblastoma Stem Cells through a SOX2-Integrin αvβ5 Axis
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    Critical Roles of Translation Initiation and RNA Uridylation in Endogenous Retroviral Expression and Neural Differentiation in Pluripotent Stem Cells
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  53. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Inhibition of the catalytic subunit of DNA‐dependent protein kinase (DNA‐PKcs) stimulates osteoblastogenesis by potentiating bone morphogenetic protein 2 (BMP2) responses
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  54. elifesciences.org elifesciences.org
    A virus-packageable CRISPR screen identifies host factors mediating interferon inhibition of HIV
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  55. link.springer.com link.springer.com
    A Modified Lentivirus-Based Reporter for Magnetic Separation of Cancer Stem Cells
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    YTHDF2/3 Are Required for Somatic Reprogramming through Different RNA Deadenylation Pathways
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  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Locally acting transcription factors regulate p53-dependent cis-regulatory element activity
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  58. www.sciencedirect.com www.sciencedirect.com
    A Single-Cell Transcriptomics CRISPR-Activation Screen Identifies Epigenetic Regulators of the Zygotic Genome Activation Program
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  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    lentiMPRA and MPRAflow for high-throughput functional characterization of gene regulatory elements
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    The G3BP1-Family-USP10 Deubiquitinase Complex Rescues Ubiquitinated 40S Subunits of Ribosomes Stalled in Translation from Lysosomal Degradation
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    Targeted Degradation of SLC Transporters Reveals Amenability of Multi-Pass Transmembrane Proteins to Ligand-Induced Proteolysis
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  62. bioone.org bioone.org
    Endogenous Retrovirus Activation as a Key Mechanism of Anti-Tumor Immune Response in Radiotherapy
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  63. www.sciencedirect.com www.sciencedirect.com
    Absolute Quantification of Transcription Factors Reveals Principles of Gene Regulation in Erythropoiesis
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    Rational Design of Allosteric and Selective Inhibitors of the Molecular Chaperone TRAP1
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    Microglia Dysfunction Caused by the Loss of Rhoa Disrupts Neuronal Physiology and Leads to Neurodegeneration
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  66. www.nature.com www.nature.com
    Synapse elimination activates a coordinated homeostatic presynaptic response in an autaptic circuit
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    Attenuated Epigenetic Suppression of Muscle Stem Cell Necroptosis Is Required for Efficient Regeneration of Dystrophic Muscles
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  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CXCL12-induced rescue of cortical dendritic spines and cognitive flexibility
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  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    JNK signalling regulates antioxidant responses in neurons
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    m.3243A > G-Induced Mitochondrial Dysfunction Impairs Human Neuronal Development and Reduces Neuronal Network Activity and Synchronicity
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    An Optimized Protocol for Human Direct Cardiac Reprogramming
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    RSK2 Maintains Adult Estrogen Homeostasis by Inhibiting ERK1/2-Mediated Degradation of Estrogen Receptor Alpha
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      Addgene Cat #12259

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    Epigenetic Silencing of CDR1as Drives IGF2BP3-Mediated Melanoma Invasion and Metastasis
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    A Model of Differential Mammary Growth Initiation by Stat3 and Asymmetric Integrin-α6 Inheritance
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  75. www.jbc.org www.jbc.org
    The small EF-hand protein CALML4 functions as a critical myosin light chain within the intermicrovillar adhesion complex
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    NF45 and NF90 Regulate Mitotic Gene Expression by Competing with Staufen-Mediated mRNA Decay
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    FADD and Caspase-8 Regulate Gut Homeostasis and Inflammation by Controlling MLKL- and GSDMD-Mediated Death of Intestinal Epithelial Cells
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    METTL1 Promotes let-7 MicroRNA Processing via m7G Methylation
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    Neurofibromin Is an Estrogen Receptor-α Transcriptional Co-repressor in Breast Cancer
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    Challenges and Reinterpretation of Antibody-Based Research on Phosphorylation of Tyr307 on PP2Ac
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    A P53-Independent DNA Damage Response Suppresses Oncogenic Proliferation and Genome Instability
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    Early B Cell Factor Activity Controls Developmental and Adaptive Thermogenic Gene Programming in Adipocytes
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    FKBP10 Regulates Protein Translation to Sustain Lung Cancer Growth
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    Macrophage Exosomes Resolve Atherosclerosis by Regulating Hematopoiesis and Inflammation via MicroRNA Cargo
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  85. pubs.acs.org pubs.acs.org
    Proximal Biotinylation Based Combinatory Approach for Isolating Integral Plasma Membrane Proteins
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      DOI: 10.1021/acs.jproteome.0c00113

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  86. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Co-culture Systems of Drug-Treated Acute Myeloid Leukemia Cells and T Cells for In Vitro and In Vivo Study
    1
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      pMD2.G

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  87. www.sciencedirect.com www.sciencedirect.com
    Chimeric Antigen Receptor Designed to Prevent Ubiquitination and Downregulation Showed Durable Antitumor Efficacy
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  88. www.sciencedirect.com www.sciencedirect.com
    Targeting DGAT1 Ameliorates Glioblastoma by Increasing Fat Catabolism and Oxidative Stress
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  89. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    The oncofetal RNA-binding protein IGF2BP1 is a druggable, post-transcriptional super-enhancer of E2F-driven gene expression in cancer
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  90. www.sciencedirect.com www.sciencedirect.com
    Integrated Transcriptome and Network Analysis Reveals Spatiotemporal Dynamics of Calvarial Suturogenesis
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  91. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A CRISPR knockout negative screen reveals synergy between CDKs inhibitor and metformin in the treatment of human cancer in vitro and in vivo
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  92. Aug 2020
  93. pubs.acs.org pubs.acs.org
    Cell-Based Ligand Discovery for the ENL YEATS Domain
    1
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      DOI: 10.1021/acschembio.0c00124

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  94. Jan 2020
  95. www.sciencedirect.com www.sciencedirect.com
    Suppressing Aneuploidy-Associated Phenotypes Improves the Fitness of Trisomy 21 Cells
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  96. www.sciencedirect.com www.sciencedirect.com
    A CEP104-CSPP1 Complex Is Required for Formation of Primary Cilia Competent in Hedgehog Signaling
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  97. www.sciencedirect.com www.sciencedirect.com
    Functional Relevance of Interleukin-1 Receptor Inter-domain Flexibility for Cytokine Binding and Signaling
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  98. www.sciencedirect.com www.sciencedirect.com
    Cell-Cycle Asynchrony Generates DNA Damage at Mitotic Entry in Polyploid Cells
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  99. www.sciencedirect.com www.sciencedirect.com
    RUVBL1/RUVBL2 ATPase Activity Drives PAQosome Maturation, DNA Replication and Radioresistance in Lung Cancer
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  100. www.nature.com www.nature.com
    Genetic modification of primary human B cells to model high-grade lymphoma
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  101. www.sciencedirect.com www.sciencedirect.com
    Shank Proteins Couple the Endocytic Zone to the Postsynaptic Density to Control Trafficking and Signaling of Metabotropic Glutamate Receptor 5
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      RRID:Addgene_12259

      DOI: 10.1016/j.celrep.2019.08.102

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  102. www.sciencedirect.com www.sciencedirect.com
    Integrin-α3 Is a Functional Marker of Ex Vivo Expanded Human Long-Term Hematopoietic Stem Cells
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      RRID:Addgene_12259

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  103. elifesciences.org elifesciences.org
    Rare missense variants in the human cytosolic antibody receptor preserve antiviral function
    1
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  104. www.sciencedirect.com www.sciencedirect.com
    Altered m6A Modification of Specific Cellular Transcripts Affects Flaviviridae Infection
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      RRID:Addgene_12259

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  105. www.sciencedirect.com www.sciencedirect.com
    PCIF1 Catalyzes m6Am mRNA Methylation to Regulate Gene Expression
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  106. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dynamic regulation of chromatin accessibility by pluripotency transcription factors across the cell cycle
    1
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      DOI: 10.7554/eLife.50087

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    ncbi.nlm.nih.gov/pmc/articles/PMC6890464/
  107. academic.oup.com academic.oup.com
    Chronic intermittent tachypacing by an optogenetic approach induces arrhythmia vulnerability in human engineered heart tissue
    1
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      RRID:Addgene_12259

      DOI: 10.1093/cvr/cvz245

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    academic.oup.com/cardiovascres/advance-article/doi/10.1093/cvr/cvz245/5584236
  108. www.sciencedirect.com www.sciencedirect.com
    Mechanisms of Progression of Myeloid Preleukemia to Transformed Myeloid Leukemia in Children with Down Syndrome
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  109. link.springer.com link.springer.com
    Essential thrombocytosis attributed to <Emphasis Type="Italic">JAK2</Emphasis>-T875N germline mutation
    1
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      plasmid_12259

      DOI: 10.1007/s12185-019-02725-8

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  110. elifesciences.org elifesciences.org
    PUMILIO, but not RBMX, binding is required for regulation of genomic stability by noncoding RNA NORAD
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      plasmid_12259

      DOI: 10.7554/eLife.48625

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  111. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Semaphorin4D Induces Inhibitory Synapse Formation by Rapid Stabilization of Presynaptic Boutons via MET Coactivation
    1
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      RRID:Addgene_12259

      DOI: 10.1523/JNEUROSCI.0215-19.2019

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  112. www.sciencedirect.com www.sciencedirect.com
    Aryl Sulfonamides Degrade RBM39 and RBM23 by Recruitment to CRL4-DCAF15
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      RRID:Addgene_12259

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  113. www.sciencedirect.com www.sciencedirect.com
    HOTTIP lncRNA Promotes Hematopoietic Stem Cell Self-Renewal Leading to AML-like Disease in Mice
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  114. www.sciencedirect.com www.sciencedirect.com
    Reduction of Global H3K27me3 Enhances HER2/ErbB2 Targeted Therapy
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  115. elifesciences.org elifesciences.org
    USP49 potently stabilizes APOBEC3G protein by removing ubiquitin and inhibits HIV-1 replication
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      Plasmid_12259

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  116. cancerres.aacrjournals.org cancerres.aacrjournals.org
    Inhibition of Dipeptidyl Peptidase-4 Accelerates Epithelial–Mesenchymal Transition and Breast Cancer Metastasis via the CXCL12/CXCR4/mTOR Axis
    1
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      plasmid_12259

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    Endogenous IGF Signaling Directs Heterogeneous Mesoderm Differentiation in Human Embryonic Stem Cells
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  118. wellcomeopenresearch.org wellcomeopenresearch.org
    A CRISPR/Cas9 genome editing pipeline in the EndoC-βH1 cell line to study genes implicated in beta cell function
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      DOI: 10.12688/wellcomeopenres.15447.1

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    PRDM16 Maintains Homeostasis of the Intestinal Epithelium by Controlling Region-Specific Metabolism
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      DOI: 10.1016/j.stem.2019.08.017

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  120. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Ly49R activation receptor drives self-MHC–educated NK cell immunity against cytomegalovirus infection
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      DOI: 10.1073/pnas.1913064117

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  121. elifesciences.org elifesciences.org
    FAK activity sustains intrinsic and acquired ovarian cancer resistance to platinum chemotherapy
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      Plasmid_12259

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  122. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Host signaling and EGR1 transcriptional control of human cytomegalovirus replication and latency
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      DOI: 10.1371/journal.ppat.1008037

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  123. www.sciencedirect.com www.sciencedirect.com
    Activation of PARP-1 by snoRNAs Controls Ribosome Biogenesis and Cell Growth via the RNA Helicase DDX21
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      RRID:Addgene_12259

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  124. cancerres.aacrjournals.org cancerres.aacrjournals.org
    Elevated Heme Synthesis and Uptake Underpin Intensified Oxidative Metabolism and Tumorigenic Functions in Non–Small Cell Lung Cancer Cells
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      RRID:Addgene_12259

      DOI: 10.1158/0008-5472.CAN-18-2156

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  125. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Outside‐in regulation of the readily releasable pool of synaptic vesicles by α2δ‐1
    1
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      DOI: 10.1096/fj.201901551R

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  126. cancerres.aacrjournals.org cancerres.aacrjournals.org
    Enhancer Domains in Gastrointestinal Stromal Tumor Regulate KIT Expression and Are Targetable by BET Bromodomain Inhibition
    1
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      Addgene_12259

      DOI: 10.1158/0008-5472.CAN-18-1888

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    cancerres.aacrjournals.org/content/79/5/994
  127. www.nature.com www.nature.com
    A MYC–GCN2–eIF2α negative feedback loop limits protein synthesis to prevent MYC-dependent apoptosis in colorectal cancer
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      RRID:Addgene_12259

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  128. link.springer.com link.springer.com
    Evaluation of reference genes for quantitative real-time PCR in Wharton’s Jelly-derived mesenchymal stem cells after lentiviral transduction and differentiation
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      RRID:Addgene_12259

      DOI: 10.1007/s11033-019-05207-6

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  129. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Stimulation of Piezo1 by mechanical signals promotes bone anabolism
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      DOI: 10.7554/eLife.49631

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  130. www.sciencedirect.com www.sciencedirect.com
    MIGA2 Links Mitochondria, the ER, and Lipid Droplets and Promotes De Novo Lipogenesis in Adipocytes
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      DOI: 10.1016/j.molcel.2019.09.011

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  131. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HIV-1 nuclear import in macrophages is regulated by CPSF6-capsid interactions at the nuclear pore complex
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      DOI: 10.7554/eLife.41800

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  132. www.sciencedirect.com www.sciencedirect.com
    Increased Serine and One-Carbon Pathway Metabolism by PKCλ/ι Deficiency Promotes Neuroendocrine Prostate Cancer
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      RRID:Addgene_12259

      DOI: 10.1016/j.ccell.2019.01.018

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  133. www.sciencedirect.com www.sciencedirect.com
    TBK1 Suppresses RIPK1-Driven Apoptosis and Inflammation during Development and in Aging
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      DOI: 10.1016/j.cell.2018.07.041

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    Cell Survival and Cytokine Release after Inflammasome Activation Is Regulated by the Toll-IL-1R Protein SARM
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      DOI: 10.1016/j.immuni.2019.04.005

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    Widespread and Functional RNA Circularization in Localized Prostate Cancer
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      RRID:Addgene_12259

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  136. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chronic optogenetic induction of stress granules is cytotoxic and reveals the evolution of ALS-FTD pathology
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      DOI: 10.7554/eLife.39578

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  137. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  139. www.nature.com www.nature.com
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  140. www.sciencedirect.com www.sciencedirect.com
    Genome-wide CRISPR-Cas9 Screen Identifies Leukemia-Specific Dependence on a Pre-mRNA Metabolic Pathway Regulated by DCPS
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      Plasmid_12259

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    Acid Suspends the Circadian Clock in Hypoxia through Inhibition of mTOR
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    Polarity Acquisition in Cortical Neurons Is Driven by Synergistic Action of Sox9-Regulated Wwp1 and Wwp2 E3 Ubiquitin Ligases and Intronic miR-140
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  143. www.sciencedirect.com www.sciencedirect.com
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      DOI: 10.1016/j.cels.2017.10.010

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  144. www.sciencedirect.com www.sciencedirect.com
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      DOI: 10.1016/j.stem.2019.01.011

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      Plasmid_12259

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    sciencedirect.com/science/article/pii/S2211124719300944
  146. www.sciencedirect.com www.sciencedirect.com
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  147. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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      plasmid_12259

      DOI: 10.1186/s40425-019-0575-3

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  149. www.sciencedirect.com www.sciencedirect.com
    Transmembrane 4 L Six Family Member 5 Senses Arginine for mTORC1 Signaling
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      Addgene_12259

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  150. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  151. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  153. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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