2,458 Matching Annotations
  1. Jan 2020
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    AXIN2+ Pericentral Hepatocytes Have Limited Contributions to Liver Homeostasis and Regeneration
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      DOI: 10.1016/j.stem.2019.10.011

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    sciencedirect.com/science/article/pii/S1934590919304321
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    ERG Controls B Cell Development by Promoting Igh V-to-DJ Recombination
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      DOI: 10.1016/j.celrep.2019.10.098

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    Differential Activation of the Transcription Factor IRF1 Underlies the Distinct Immune Responses Elicited by Type I and III Interferons
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      DOI: 10.1016/j.immuni.2019.07.007

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    A potent voltage-gated calcium channel inhibitor engineered from a nanobody targeted to auxiliary CaVβ subunits
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      DOI: 10.7554/eLife.49253

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    A bivalent antihypertensive vaccine targeting L‐type calcium channel and angiotensin II type 1 receptor
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      DOI: 10.1111/bph.14875

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    The Cardiac Microenvironment Instructs Divergent Monocyte Fates and Functions in Myocarditis
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    PRIMPOL-Mediated Adaptive Response Suppresses Replication Fork Reversal in BRCA-Deficient Cells
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    Protein Amounts of the MYC Transcription Factor Determine Germinal Center B Cell Division Capacity
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    Single-Cell Profiling Reveals Sex, Lineage, and Regional Diversity in the Mouse Kidney
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    Liver Is a Generative Site for the B Cell Response to Ehrlichia muris
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    The Bone Marrow Protects and Optimizes Immunological Memory during Dietary Restriction
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      DOI: 10.1016/j.cell.2019.07.049

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    FOXA2 Is Required for Enhancer Priming during Pancreatic Differentiation
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    Rapid and iterative genome editing in the malaria parasite Plasmodium knowlesi provides new tools for P. vivax research
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      DOI: 10.7554/eLife.45829

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    BPS Publications
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      DOI: 10.1111/bph.14784

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    Hepatocytes Delete Regulatory T Cells by Enclysis, a CD4+ T Cell Engulfment Process
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      DOI: 10.1016/j.celrep.2019.09.068

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    Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries
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      DOI: 10.1016/j.cell.2017.12.009

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    RUVBL1/RUVBL2 ATPase Activity Drives PAQosome Maturation, DNA Replication and Radioresistance in Lung Cancer
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    Orphan Nuclear Receptor NR2F6 Suppresses T Follicular Helper Cell Accumulation through Regulation of IL-21
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      DOI: 10.1016/j.celrep.2019.08.024

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    Dectin-1 Binding to Annexins on Apoptotic Cells Induces Peripheral Immune Tolerance via NADPH Oxidase-2
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    WNT-Mediated Regulation of FOXO1 Constitutes a Critical Axis Maintaining Pubertal Mammary Stem Cell Homeostasis
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      DOI: 10.1016/j.devcel.2017.10.007

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    sciencedirect.com/science/article/pii/S1534580717308201
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    Oligodendrocyte Intrinsic miR-27a Controls Myelination and Remyelination
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    sciencedirect.com/science/article/pii/S2211124719311970
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    Defects in Antiviral T Cell Responses Inflicted by Aging-Associated miR-181a Deficiency
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      DOI: 10.1016/j.celrep.2019.10.044

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    Increased Hematopoietic Extracellular RNAs and Vesicles in the Lung during Allergic Airway Responses
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      DOI: 10.1016/j.celrep.2019.01.002

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      DOI: 10.3389/fimmu.2019.00919

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    Spatially Restricted Stromal Wnt Signaling Restrains Prostate Epithelial Progenitor Growth through Direct and Indirect Mechanisms
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      DOI: 10.1016/j.stem.2019.03.010

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    A Subset of Type I Conventional Dendritic Cells Controls Cutaneous Bacterial Infections through VEGFα-Mediated Recruitment of Neutrophils
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    The Pseudo Natural Product Myokinasib Is a Myosin Light Chain Kinase 1 Inhibitor with Unprecedented Chemotype
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      DOI: 10.1111/bph.14603

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      DOI: 10.7554/eLife.44161

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    Small‐molecule inhibition of prostaglandin E receptor 2 impairs cyclooxygenase‐associated malignant glioma growth
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      DOI: 10.1111/bph.14622

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    Suppressing Mitochondrial Respiration Is Critical for Hypoxia Tolerance in the Fetal Growth Plate
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    Oncogenic Notch Promotes Long-Range Regulatory Interactions within Hyperconnected 3D Cliques
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    A Multiplexed Assay for Exon Recognition Reveals that an Unappreciated Fraction of Rare Genetic Variants Cause Large-Effect Splicing Disruptions
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    Single-Dose CpG Immunization Protects Against a Heterosubtypic Challenge and Generates Antigen-Specific Memory T Cells
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    Blocking Stroke-Induced Immunodeficiency Increases CNS Antigen-Specific Autoreactivity But Does Not Worsen Functional Outcome after Experimental Stroke
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    Characterization of Oligodendroglial Populations in Mouse Demyelinating Disease Using Flow Cytometry: Clues for MS Pathogenesis
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    The FOXO1 Transcription Factor Instructs the Germinal Center Dark Zone Program
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    RHOA G17V Induces T Follicular Helper Cell Specification and Promotes Lymphomagenesis
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    CD157 Marks Tissue-Resident Endothelial Stem Cells with Homeostatic and Regenerative Properties
    1
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      FlowJo

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    The Histone Chaperones ASF1 and CAF-1 Promote MMS22L-TONSL-Mediated Rad51 Loading onto ssDNA during Homologous Recombination in Human Cells
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      FlowJo

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  87. onlinelibrary.wiley.com onlinelibrary.wiley.com
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    Tumor-Repopulating Cells Induce PD-1 Expression in CD8+ T Cells by Transferring Kynurenine and AhR Activation
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      FlowJo

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    Genome-wide CRISPR-Cas9 Screen Identifies Leukemia-Specific Dependence on a Pre-mRNA Metabolic Pathway Regulated by DCPS
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    Commensal Microbes Induce Serum IgA Responses that Protect against Polymicrobial Sepsis
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    Dual Modifications of α-Galactosylceramide Synergize to Promote Activation of Human Invariant Natural Killer T Cells and Stimulate Anti-tumor Immunity
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      FlowJo

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    IRF8 Regulates Transcription of Naips for NLRC4 Inflammasome Activation
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    Ribosome Levels Selectively Regulate Translation and Lineage Commitment in Human Hematopoiesis
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    Synergy between the KEAP1/NRF2 and PI3K Pathways Drives Non-Small-Cell Lung Cancer with an Altered Immune Microenvironment
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    Cholesterol Homeostatic Regulator SCAP-SREBP2 Integrates NLRP3 Inflammasome Activation and Cholesterol Biosynthetic Signaling in Macrophages
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      Flowjo

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    The Histone Chaperone FACT Coordinates H2A.X-Dependent Signaling and Repair of DNA Damage
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      FlowJo

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    Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme Formation
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      FlowJo

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    CtIP-Mediated Fork Protection Synergizes with BRCA1 to Suppress Genomic Instability upon DNA Replication Stress
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    Protein Barcodes Enable High-Dimensional Single-Cell CRISPR Screens
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      FlowJo

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  101. www.sciencedirect.com www.sciencedirect.com
    TLR8-Mediated Metabolic Control of Human Treg Function: A Mechanistic Target for Cancer Immunotherapy
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      FlowJo

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    Dysregulated Microbial Fermentation of Soluble Fiber Induces Cholestatic Liver Cancer
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      FlowJo

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    Targeting Processive Transcription Elongation via SEC Disruption for MYC-Induced Cancer Therapy
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      FlowJo

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    The Lineage-Defining Transcription Factors SOX2 and NKX2-1 Determine Lung Cancer Cell Fate and Shape the Tumor Immune Microenvironment
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      FlowJo

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    ZNF598 Is a Quality Control Sensor of Collided Ribosomes
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      FlowJo

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    Tumor-Derived cGAMP Triggers a STING-Mediated Interferon Response in Non-tumor Cells to Activate the NK Cell Response
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      FlowJo

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    CRISPR-Mediated Programmable 3D Genome Positioning and Nuclear Organization
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      FlowJo

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  109. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Metformin Targets Mitochondrial Electron Transport to Reduce Air-Pollution-Induced Thrombosis
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    ncbi.nlm.nih.gov/pmc/articles/PMC6365216/
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    CD8+ T Cell Priming in Established Chronic Viral Infection Preferentially Directs Differentiation of Memory-like Cells for Sustained Immunity
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      Flow Jo

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    Distinct Effector B Cells Induced by Unregulated Toll-like Receptor 7 Contribute to Pathogenic Responses in Systemic Lupus Erythematosus
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      FlowJo

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    The Majority of CD45– Ter119– CD31– Bone Marrow Cell Fraction Is of Hematopoietic Origin and Contains Erythroid and Lymphoid Progenitors
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    Complement C5a Fosters Squamous Carcinogenesis and Limits T Cell Response to Chemotherapy
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    MYC Interacts with the G9a Histone Methyltransferase to Drive Transcriptional Repression and Tumorigenesis
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      FlowJo

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    Muscle Satellite Cell Cross-Talk with a Vascular Niche Maintains Quiescence via VEGF and Notch Signaling
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    Intestinal Dysmotility Syndromes following Systemic Infection by Flaviviruses
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      FlowJo

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    Inheritance of CENP-A Nucleosomes during DNA Replication Requires HJURP
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      FlowJo

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    Immune Checkpoint Inhibition Overcomes ADCP-Induced Immunosuppression by Macrophages
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      FlowJo

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    Genetic Modulation of RNA Splicing with a CRISPR-Guided Cytidine Deaminase
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    Single-Cell Transcriptomic Analysis of Cardiac Differentiation from Human PSCs Reveals HOPX-Dependent Cardiomyocyte Maturation
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      FlowJo

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    An Endothelial-to-Adipocyte Extracellular Vesicle Axis Governed by Metabolic State
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  122. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Sulfatide isoform pattern in cerebrospinal fluid discriminates progressive MS from relapsing‐remitting MS
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      FlowJo

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    CD8+ T Cell Activation Leads to Constitutive Formation of Liver Tissue-Resident Memory T Cells that Seed a Large and Flexible Niche in the Liver
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      FlowJo

      Curator: @evieth

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    Type I Interferon Receptor Signaling of Neurons and Astrocytes Regulates Microglia Activation during Viral Encephalitis
    1
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    Secreted IgD Amplifies Humoral T Helper 2 Cell Responses by Binding Basophils via Galectin-9 and CD44
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      FlowJo

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    Regulatory T Cells Promote Macrophage Efferocytosis during Inflammation Resolution
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      FlowJo

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    B Cells Are the Dominant Antigen-Presenting Cells that Activate Naive CD4+ T Cells upon Immunization with a Virus-Derived Nanoparticle Antigen
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      FlowJo

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    The Mevalonate Pathway Is a Druggable Target for Vaccine Adjuvant Discovery
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      FlowJo

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  129. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    Subversion of Systemic Glucose Metabolism as a Mechanism to Support the Growth of Leukemia Cells
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      Flowjo

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    Epigenetic Restoration of Fetal-like IGF1 Signaling Inhibits Leukemia Stem Cell Activity
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    NONO Detects the Nuclear HIV Capsid to Promote cGAS-Mediated Innate Immune Activation
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      Flow-Jo

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    Vascular and Neurogenic Rejuvenation in Aging Mice by Modulation of ASM
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      FlowJo

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    A Metabolism-Based Quorum Sensing Mechanism Contributes to Termination of Inflammatory Responses
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      FlowJo

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    The BRCT Domains of the BRCA1 and BARD1 Tumor Suppressors Differentially Regulate Homology-Directed Repair and Stalled Fork Protection
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      FlowJo

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    Prospective Isolation and Characterization of Genetically and Functionally Distinct AML Subclones
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      FlowJo

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    Translational and HIF-1α-Dependent Metabolic Reprogramming Underpin Metabolic Plasticity and Responses to Kinase Inhibitors and Biguanides
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      FlowJo

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  139. elifesciences.org elifesciences.org
    Glutathione de novo synthesis but not recycling process coordinates with glutamine catabolism to control redox homeostasis and directs murine T cell differentiation
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  140. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Functionally Defined In Vivo Astrocyte Population Identified by c-Fos Activation in a Mouse Model of Multiple Sclerosis Modulated by S1P Signaling: Immediate-Early Astrocytes (ieAstrocytes)
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  141. www.sciencedirect.com www.sciencedirect.com
    LC3-Associated Phagocytosis in Myeloid Cells Promotes Tumor Immune Tolerance
    1
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      FlowJo

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  142. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Early Targeting of L-Selectin on Leukocytes Promotes Recovery after Spinal Cord Injury, Implicating Novel Mechanisms of Pathogenesis
    1
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      FlowJo

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  143. www.sciencedirect.com www.sciencedirect.com
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    SYK-CARD9 Signaling Axis Promotes Gut Fungi-Mediated Inflammasome Activation to Restrict Colitis and Colon Cancer
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    The Adaptor Protein CARD9 Protects against Colon Cancer by Restricting Mycobiota-Mediated Expansion of Myeloid-Derived Suppressor Cells
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      Flow Jo

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    CD56 Expression Marks Human Group 2 Innate Lymphoid Cell Divergence from a Shared NK Cell and Group 3 Innate Lymphoid Cell Developmental Pathway
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      FlowJo

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    An Atypical Parvovirus Drives Chronic Tubulointerstitial Nephropathy and Kidney Fibrosis
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      FlowJo

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    A Bacterial Chromosome Structuring Protein Binds Overtwisted DNA to Stimulate Type II Topoisomerases and Enable DNA Replication
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      FlowJo

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  149. www.sciencedirect.com www.sciencedirect.com
    The Inhibitory Innate Immune Sensor NLRP12 Maintains a Threshold against Obesity by Regulating Gut Microbiota Homeostasis
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      Flowjo

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    A Membrane Potential- and Calpain-Dependent Reversal of Caspase-1 Inhibition Regulates Canonical NLRP3 Inflammasome
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      FlowJo

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  151. elifesciences.org elifesciences.org
    Tryparedoxin peroxidase-deficiency commits trypanosomes to ferroptosis-type cell death
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      FlowJo

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    The Ciliary Machinery Is Repurposed for T Cell Immune Synapse Trafficking of LCK
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      FlowJo

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    Disruption of the β1L Isoform of GABP Reverses Glioblastoma Replicative Immortality in a TERT Promoter Mutation-Dependent Manner
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      FlowJo

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  154. www.sciencedirect.com www.sciencedirect.com
    Mutant NPM1 Maintains the Leukemic State through HOX Expression
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      FlowJo

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    POLE3-POLE4 Is a Histone H3-H4 Chaperone that Maintains Chromatin Integrity during DNA Replication
    1
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      FlowJo

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  156. www.sciencedirect.com www.sciencedirect.com
    MEF2B Instructs Germinal Center Development and Acts as an Oncogene in B Cell Lymphomagenesis
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      FlowJo

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    Identification of Chemotherapy-Induced Leukemic-Regenerating Cells Reveals a Transient Vulnerability of Human AML Recurrence
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      FlowJo

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  158. www.nature.com www.nature.com
    RANKL/RANK control Brca1 mutation-driven mammary tumors
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      FlowJo

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  159. www.sciencedirect.com www.sciencedirect.com
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    β-Hydroxybutyrate Prevents Vascular Senescence through hnRNP A1-Mediated Upregulation of Oct4
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      FlowJo

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    Transcriptional and Translational Differences of Microglia from Male and Female Brains
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      FlowJo

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    ATR-Mediated Global Fork Slowing and Reversal Assist Fork Traverse and Prevent Chromosomal Breakage at DNA Interstrand Cross-Links
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      FlowJo

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  163. journals.plos.org journals.plos.org
    A high-throughput screen of real-time ATP levels in individual cells reveals mechanisms of energy failure
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      FlowJo

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    Insulin Receptor-Mediated Stimulation Boosts T Cell Immunity during Inflammation and Infection
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    Neurons under T Cell Attack Coordinate Phagocyte-Mediated Synaptic Stripping
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    Daily Onset of Light and Darkness Differentially Controls Hematopoietic Stem Cell Differentiation and Maintenance
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    Flow Cytometry of Mouse and Human Adipocytes for the Analysis of Browning and Cellular Heterogeneity
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      FlowJo flow cytometry

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  168. content.iospress.com content.iospress.com
    NO-Dependent Akt Inactivation by S-Nitrosylation as a Possible Mechanism of STZ-Induced Neuronal Insulin Resistance
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    Self-Maintaining Gut Macrophages Are Essential for Intestinal Homeostasis
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    The Chemokine Receptor CCR8 Promotes the Migration of Dendritic Cells into the Lymph Node Parenchyma to Initiate the Allergic Immune Response
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      FlowJo

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    Lung γδ T Cells Mediate Protective Responses during Neonatal Influenza Infection that Are Associated with Type 2 Immunity
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    Gasdermin D Restrains Type I Interferon Response to Cytosolic DNA by Disrupting Ionic Homeostasis
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      FlowJo

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  173. onlinelibrary.wiley.com onlinelibrary.wiley.com
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    A Map of Toll-like Receptor Expression in the Intestinal Epithelium Reveals Distinct Spatial, Cell Type-Specific, and Temporal Patterns
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    Non-canonical NF-κB Antagonizes STING Sensor-Mediated DNA Sensing in Radiotherapy
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    TBK1 Suppresses RIPK1-Driven Apoptosis and Inflammation during Development and in Aging
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      FlowJo

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    SIRT1 Activation Disrupts Maintenance of Myelodysplastic Syndrome Stem and Progenitor Cells by Restoring TET2 Function
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      FlowJo

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    Memory B Cells Activate Brain-Homing, Autoreactive CD4+ T Cells in Multiple Sclerosis
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    Quiescent Endothelial Cells Upregulate Fatty Acid β-Oxidation for Vasculoprotection via Redox Homeostasis
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      FlowJo

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    Alveolar Macrophages Provide an Early Mycobacterium tuberculosis Niche and Initiate Dissemination
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      FlowJo

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  183. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Establishment and characterization of a telomerase‐immortalized porcine bronchial epithelial cell line
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    A Chromatin Basis for Cell Lineage and Disease Risk in the Human Pancreas
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      FlowJo

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    A Single-Agent Dual-Specificity Targeting of FOLR1 and DR5 as an Effective Strategy for Ovarian Cancer
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      FlowJo

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    Histone Ubiquitination by the DNA Damage Response Is Required for Efficient DNA Replication in Unperturbed S Phase
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      FlowJo

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    Neutralizing Gatad2a-Chd4-Mbd3/NuRD Complex Facilitates Deterministic Induction of Naive Pluripotency
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      FlowJo

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    Cytosolic Aspartate Availability Determines Cell Survival When Glutamine Is Limiting
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      FlowJo

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    GATA/Heme Multi-omics Reveals a Trace Metal-Dependent Cellular Differentiation Mechanism
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      FlowJo

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    Hoxc-Dependent Mesenchymal Niche Heterogeneity Drives Regional Hair Follicle Regeneration
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      FlowJo

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    Antibiotic-induced acceleration of type 1 diabetes alters maturation of innate intestinal immunity
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    Dissecting the Functional Consequences of De Novo DNA Methylation Dynamics in Human Motor Neuron Differentiation and Physiology
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    Dysregulated IL-18 Is a Key Driver of Immunosuppression and a Possible Therapeutic Target in the Multiple Myeloma Microenvironment
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      FlowJo

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    Integrated analysis of DNA methylome and transcriptome identified CREB5 as a novel risk gene contributing to recurrent pregnancy loss
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    Urea Cycle Dysregulation Generates Clinically Relevant Genomic and Biochemical Signatures
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  198. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Distinct Bone Marrow Sources of Pleiotrophin Control Hematopoietic Stem Cell Maintenance and Regeneration
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    Tbx6 Induces Nascent Mesoderm from Pluripotent Stem Cells and Temporally Controls Cardiac versus Somite Lineage Diversification
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    Generation of Tumor-Reactive T Cells by Co-culture of Peripheral Blood Lymphocytes and Tumor Organoids
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    LIGHT-HVEM Signaling in Innate Lymphoid Cell Subsets Protects Against Enteric Bacterial Infection
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    LAG3+ Regulatory T Cells Restrain Interleukin-23-Producing CX3CR1+ Gut-Resident Macrophages during Group 3 Innate Lymphoid Cell-Driven Colitis
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    Conventional and Neo-Antigenic Peptides Presented by β Cells Are Targeted by Circulating Naïve CD8+ T Cells in Type 1 Diabetic and Healthy Donors
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