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Jan 2020
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RAD51AP1 Is an Essential Mediator of Alternative Lengthening of Telomeres

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Metabolic Control of Astrocyte Pathogenic Activity via cPLA2-MAVS

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RNase L Reprograms Translation by Widespread mRNA Turnover Escaped by Antiviral mRNAs

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Non-coding RNA Transcription in Tetrahymena Meiotic Nuclei Requires Dedicated Mediator Complex-Associated Proteins

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Microbial Metabolite Signaling Is Required for Systemic Iron Homeostasis

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HIV-1 Vif Triggers Cell Cycle Arrest by Degrading Cellular PPP2R5 Phospho-regulators

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Functional expression of electrogenic sodium bicarbonate cotransporter 1 (NBCe1) in mouse cortical astrocytes is dependent on S255‐257 and regulated by mTOR

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  DOI: 10.1002/glia.23682
  
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onlinelibrary.wiley.com/doi/abs/10.1002/glia.23682
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PKC-delta mediates mineralocorticoid receptor activation by angiotensin II to modulate smooth muscle cell function

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academic.oup.com/endo/article/160/9/2101/5542343
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RUNX1-ETO Depletion in t(8;21) AML Leads to C/EBPα- and AP-1-Mediated Alterations in Enhancer-Promoter Interaction

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sciencedirect.com/science/article/pii/S2211124719310800
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RAG-Mediated DNA Breaks Attenuate PU.1 Activity in Early B Cells through Activation of a SPIC-BCLAF1 Complex

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BPS Publications

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  DOI: 10.1111/bph.14714
  
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bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.14714
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BPS Publications

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  DOI: 10.1111/bph.14794
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.14794
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Different responses of PC12 cells to different pro-nerve growth factor protein variants

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  DOI: 10.1016/j.neuint.2019.104498
  
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sciencedirect.com/science/article/pii/S0197018619301500
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BPS Publications

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  DOI: 10.1111/bph.14694
  
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bpspubs.onlinelibrary.wiley.com/doi/abs/10.1111/bph.14694
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SENP2 Suppresses Necdin Expression to Promote Brown Adipocyte Differentiation

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sciencedirect.com/science/article/pii/S2211124719309878
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Neutralization of the Positive Charges on Histone Tails by RNA Promotes an Open Chromatin Structure

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  DOI: 10.1016/j.chembiol.2019.08.002
  
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sciencedirect.com/science/article/pii/S245194561930248X
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The N-Degron Pathway Mediates ER-phagy

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Identification of FUBP1 as a Long Tail Cancer Driver and Widespread Regulator of Tumor Suppressor and Oncogene Alternative Splicing

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CRISPR/Cas9 Screens Reveal Multiple Layers of B cell CD40 Regulation

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Mesothelial Cell HIF1α Expression Is Metabolically Downregulated by Metformin to Prevent Oncogenic Tumor-Stromal Crosstalk

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Slc6a8-Mediated Creatine Uptake and Accumulation Reprogram Macrophage Polarization via Regulating Cytokine Responses

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PPEF2 Opposes PINK1-Mediated Mitochondrial Quality Control by Dephosphorylating Ubiquitin

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Combination of antioxidants and NFAT (nuclear factor of activated T cells) inhibitor protects auditory hair cells from ototoxic insult

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  DOI: 10.1111/jnc.14921
  
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onlinelibrary.wiley.com/doi/full/10.1111/jnc.14921
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miRNA551b-3p Activates an Oncostatin Signaling Module for the Progression of Triple-Negative Breast Cancer

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cell.com/cell-reports/fulltext/S2211-1247(19)31576-1
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Effect of early-stage autophagy inhibition in BRAF V600E autophagy-dependent brain tumor cells

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  DOI: 10.1038/s41419-019-1880-y
  
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nature.com/articles/s41419-019-1880-y
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Mechanical loading stimulates hypertrophy in tissue‐engineered skeletal muscle: Molecular and phenotypic responses

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  DOI: 10.1002/jcp.28923
  
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onlinelibrary.wiley.com/doi/abs/10.1002/jcp.28923
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STING-Mediated IFI16 Degradation Negatively Controls Type I Interferon Production

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sciencedirect.com/science/article/pii/S2211124719312665
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The Hippo Pathway Effector TAZ Regulates Ferroptosis in Renal Cell Carcinoma

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Generation of three induced pluripotent cell lines (iPSCs) from an Aicardi-Goutières syndrome (AGS) patient harboring a deletion in the genomic locus of the sterile alpha motif and HD domain containing protein 1 (SAMHD1)

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sciencedirect.com/science/article/pii/S1873506119303277
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The Receptor Kinases BAK1/SERK4 Regulate Ca2+ Channel-Mediated Cellular Homeostasis for Cell Death Containment

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Loss of Slug Compromises DNA Damage Repair and Accelerates Stem Cell Aging in Mammary Epithelium

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NYX‐2925 induces metabotropic NMDAR signaling that enhances synaptic NMDAR and AMPAR

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  DOI: 10.1111/jnc.14845
  
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onlinelibrary.wiley.com/doi/10.1111/jnc.14845
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TGF‐β1 activates RSC96 Schwann cells migration and invasion through MMP‐2 and MMP‐9 activities

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  DOI: 10.1111/jnc.14913
  
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onlinelibrary.wiley.com/doi/full/10.1111/jnc.14913
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Spatial Chromosome Folding and Active Transcription Drive DNA Fragility and Formation of Oncogenic MLL Translocations

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microRNA‐141 is associated with hepatic steatosis by downregulating the sirtuin1/AMP‐activated protein kinase pathway in hepatocytes

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Gestational intermittent hypoxia induces endothelial dysfunction, reduces perivascular adiponectin and causes epigenetic changes in adult male offspring

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RUVBL1/RUVBL2 ATPase Activity Drives PAQosome Maturation, DNA Replication and Radioresistance in Lung Cancer

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Neuronal Ca2+‐dependent activator protein 1 (NCDAP1) induces neuronal cell death by activating p53 pathway following traumatic brain injury

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TRPML1 Promotes Protein Homeostasis in Melanoma Cells by Negatively Regulating MAPK and mTORC1 Signaling

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Development of MAP4 Kinase Inhibitors as Motor Neuron-Protecting Agents

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Metalloprotease-Dependent Attenuation of BMP Signaling Restricts Cardiac Neural Crest Cell Fate

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Role of GluN2A NMDA receptor in homocysteine‐induced prostaglandin E2 release from neurons

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Targeting Pathogenic Lafora Bodies in Lafora Disease Using an Antibody-Enzyme Fusion

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Rgma-induced Neo1 proteolysis promotes neural tube morphogenesis

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Sox17 Regulates a Program of Oligodendrocyte Progenitor Cell Expansion and Differentiation during Development and Repair

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Fructose-1,6-Bisphosphatase 2 Inhibits Sarcoma Progression by Restraining Mitochondrial Biogenesis

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Induced pluripotent stem cell line (PEIi003-A) derived from an apparently healthy male individual.

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Small-Molecule and CRISPR Screening Converge to Reveal Receptor Tyrosine Kinase Dependencies in Pediatric Rhabdoid Tumors

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SENP1-Sirt3 Signaling Controls Mitochondrial Protein Acetylation and Metabolism

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A PRMT5-RNF168-SMURF2 Axis Controls H2AX Proteostasis

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A multimolecular signaling complex including PrPC and LRP1 is strictly dependent on lipid rafts and is essential for the function of tissue Plasminogen Activator

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Cross-Microbial Protection via Priming a Conserved Immune Co-Receptor through Juxtamembrane Phosphorylation in Plants

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N-cadherin-regulated FGFR ubiquitination and degradation control mammalian neocortical projection neuron migration

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Systemic Root-Shoot Signaling Drives Jasmonate-Based Root Defense against Nematodes

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Structural Basis of Paxillin Recruitment by Kindlin-2 in Regulating Cell Adhesion

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TLR8 Is a Sensor of RNase T2 Degradation Products

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Donepezil‐induced oligodendrocyte differentiation is mediated through estrogen receptors

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The miR-216a-Dot1l Regulatory Axis Is Necessary and Sufficient for Müller Glia Reprogramming during Retina Regeneration

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Screening the expression of several miRNAs from TaqMan Low Density Array in traumatic brain injury: miR‐219a‐5p regulates neuronal apoptosis by modulating CCNA2 and CACUL1

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Phosphorylation-mediated interactions with TOPBP1 couple 53BP1 and 9-1-1 to control the G1 DNA damage checkpoint

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Oncogene Amplification in Growth Factor Signaling Pathways Renders Cancers Dependent on Membrane Lipid Remodeling

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Directed RNase H Cleavage of Nascent Transcripts Causes Transcription Termination

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Amyloid-like Assembly Activates a Phosphatase in the Developing Drosophila Embryo

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Protective effects of GHK-Cu in bleomycin-induced pulmonary fibrosis via anti-oxidative stress and anti-inflammation pathways

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Positive Feedback Defines the Timing, Magnitude, and Robustness of Angiogenesis

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Liver-Type Glutaminase GLS2 Is a Druggable Metabolic Node in Luminal-Subtype Breast Cancer

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PRDM16 Maintains Homeostasis of the Intestinal Epithelium by Controlling Region-Specific Metabolism

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Locomotor training with adjuvant testosterone preserves cancellous bone and promotes muscle plasticity in male rats after severe spinal cord injury

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Suppression of p16 Induces mTORC1-Mediated Nucleotide Metabolic Reprogramming

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Modulation of RNA Condensation by the DEAD-Box Protein eIF4A

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Mitochondrial Damage and Activation of the STING Pathway Lead to Renal Inflammation and Fibrosis

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Proximity RNA Labeling by APEX-Seq Reveals the Organization of Translation Initiation Complexes and Repressive RNA Granules

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mTORC1 Activation Requires DRAM-1 by Facilitating Lysosomal Amino Acid Efflux

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Activin A-induced cachectic wasting is attenuated by systemic delivery of its cognate propeptide in male mice

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Cancer Cells Upregulate NRF2 Signaling to Adapt to Autophagy Inhibition

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A Menin-MLL Inhibitor Induces Specific Chromatin Changes and Eradicates Disease in Models of MLL-Rearranged Leukemia

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Fascin Controls Metastatic Colonization and Mitochondrial Oxidative Phosphorylation by Remodeling Mitochondrial Actin Filaments

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Postmortem Cortex Samples Identify Distinct Molecular Subtypes of ALS: Retrotransposon Activation, Oxidative Stress, and Activated Glia

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YAP/TAZ Activation Drives Uveal Melanoma Initiation and Progression

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Glutamate Signaling in Hepatic Stellate Cells Drives Alcoholic Steatosis

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Inhibition of sirtuin 1 deacetylase by miR-211-5p provides a mechanism for the induction of cell death in breast cancer cells

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Autoinhibition Mechanism of the Ubiquitin-Conjugating Enzyme UBE2S by Autoubiquitination

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A Cell-Surface Membrane Protein Signature for Glioblastoma

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IL-36 promotes anti-viral immunity by boosting sensitivity to IFN-α/β in IRF1 dependent and independent manners

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H3K9me2 orchestrates inheritance of spatial positioning of peripheral heterochromatin through mitosis

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Defects in Antiviral T Cell Responses Inflicted by Aging-Associated miR-181a Deficiency

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Protein kinase B mediates insulin‐like growth factor 1‐induced phosphorylation and nuclear export of histone deacetylase 5 via NADPH oxidase 4 activation in vascular smooth muscle cells

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Targeted Degradation of a Hypoxia-Associated Non-coding RNA Enhances the Selectivity of a Small Molecule Interacting with RNA

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MicroRNA501‐5p induces p53 proteasome degradation through the activation of the mTOR/MDM2 pathway in ADPKD cells

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Widespread and Functional RNA Circularization in Localized Prostate Cancer

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Spatial Organization of Single mRNPs at Different Stages of the Gene Expression Pathway

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Axo-axonic Innervation of Neocortical Pyramidal Neurons by GABAergic Chandelier Cells Requires AnkyrinG-Associated L1CAM

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Predicted Benign and Synonymous Variants in CYP11A1 Cause Primary Adrenal Insufficiency Through Missplicing

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Electroacupuncture in rats normalizes the diabetes‐induced alterations in the septo‐hippocampal cholinergic system

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GDF15 Provides an Endocrine Signal of Nutritional Stress in Mice and Humans

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Choline Uptake and Metabolism Modulate Macrophage IL-1β and IL-18 Production

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Endoplasmic Reticulum Stress Activated by Androgen Enhances Apoptosis of Granulosa Cells via Induction of Death Receptor 5 in PCOS

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Modeling and Predicting the Activities of Trans-Acting Splicing Factors with Machine Learning

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Intrinsic High Aerobic Capacity in Male Rats Protects Against Diet-Induced Insulin Resistance

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Essential Gene Profiles for Human Pluripotent Stem Cells Identify Uncharacterized Genes and Substrate Dependencies

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Mitochondria‐coupled glucose phosphorylation develops after birth to modulate H2O2 release and calcium handling in rat brain

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3‐Mercaptopyruvate sulfurtransferase supports endothelial cell angiogenesis and bioenergetics

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Glutamine Metabolism Regulates Proliferation and Lineage Allocation in Skeletal Stem Cells

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Energetic Trade-Offs and Hypometabolic States Promote Disease Tolerance

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OTUB2 Promotes Cancer Metastasis via Hippo-Independent Activation of YAP and TAZ

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A Brain-Melanocortin-Vagus Axis Mediates Adipose Tissue Expansion Independently of Energy Intake

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Acquired Expression of Mutant Mitofusin 2 Causes Progressive Neurodegeneration and Abnormal Behavior

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Modulation of DNA Repair Systems in Blind Cavefish during Evolution in Constant Darkness

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The Mouse Microbiome Is Required for Sex-Specific Diurnal Rhythms of Gene Expression and Metabolism

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Immune Checkpoint Inhibition Overcomes ADCP-Induced Immunosuppression by Macrophages

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RSK-MASTL Pathway Delays Meiotic Exit in Mouse Zygotes to Ensure Paternal Chromosome Stability

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Vascular and Neurogenic Rejuvenation in Aging Mice by Modulation of ASM

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Multi-level Proteomics Identifies CT45 as a Chemosensitivity Mediator and Immunotherapy Target in Ovarian Cancer

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Chemoresistance of cancer floating cells is independent of their ability to form 3D structures: Implications for anticancer drug screening

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tp53 deficiency causes a wide tumor spectrum and increases embryonal rhabdomyosarcoma metastasis in zebrafish

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Hippocampal CB1 Receptors Control Incidental Associations

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Non-canonical Activation of the DNA Sensing Adaptor STING by ATM and IFI16 Mediates NF-κB Signaling after Nuclear DNA Damage

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Lin28 Signaling Supports Mammalian PNS and CNS Axon Regeneration

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Autocrine Mfge8 Signaling Prevents Developmental Exhaustion of the Adult Neural Stem Cell Pool

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The Chemokine Receptor CCR8 Promotes the Migration of Dendritic Cells into the Lymph Node Parenchyma to Initiate the Allergic Immune Response

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A Membrane Potential- and Calpain-Dependent Reversal of Caspase-1 Inhibition Regulates Canonical NLRP3 Inflammasome

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Quiescent Endothelial Cells Upregulate Fatty Acid β-Oxidation for Vasculoprotection via Redox Homeostasis

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AhR ligand aminoflavone suppresses α6‐integrin–Src–Akt signaling to attenuate tamoxifen resistance in breast cancer cells

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A Single-Agent Dual-Specificity Targeting of FOLR1 and DR5 as an Effective Strategy for Ovarian Cancer

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Activity-Dependent Degradation of the Nascentome by the Neuronal Membrane Proteasome

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The Mitochondrial-Encoded Peptide MOTS-c Translocates to the Nucleus to Regulate Nuclear Gene Expression in Response to Metabolic Stress

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G9a/GLP Complex Acts as a Bidirectional Switch to Regulate Metabotropic Glutamate Receptor-Dependent Plasticity in Hippocampal CA1 Pyramidal Neurons

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AMPK-Mediated BECN1 Phosphorylation Promotes Ferroptosis by Directly Blocking System Xc– Activity

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Small RNAs Are Trafficked from the Epididymis to Developing Mammalian Sperm

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Risk SNP-Mediated Promoter-Enhancer Switching Drives Prostate Cancer through lncRNA PCAT19

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Translational Control through Differential Ribosome Pausing during Amino Acid Limitation in Mammalian Cells

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Mitofusin 2 Regulates Axonal Transport of Calpastatin to Prevent Neuromuscular Synaptic Elimination in Skeletal Muscles

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