3,164 Matching Annotations
  1. Nov 2018
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    CtIP-Mediated Fork Protection Synergizes with BRCA1 to Suppress Genomic Instability upon DNA Replication Stress
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    sciencedirect.com/science/article/pii/S1097276518307858
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    Protein Barcodes Enable High-Dimensional Single-Cell CRISPR Screens
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    TLR8-Mediated Metabolic Control of Human Treg Function: A Mechanistic Target for Cancer Immunotherapy
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    sciencedirect.com/science/article/pii/S1550413118306284
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    Dysregulated Microbial Fermentation of Soluble Fiber Induces Cholestatic Liver Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC6232850/
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    Targeting Processive Transcription Elongation via SEC Disruption for MYC-Induced Cancer Therapy
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    The Lineage-Defining Transcription Factors SOX2 and NKX2-1 Determine Lung Cancer Cell Fate and Shape the Tumor Immune Microenvironment
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    ZNF598 Is a Quality Control Sensor of Collided Ribosomes
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    Tumor-Derived cGAMP Triggers a STING-Mediated Interferon Response in Non-tumor Cells to Activate the NK Cell Response
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    CRISPR-Mediated Programmable 3D Genome Positioning and Nuclear Organization
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    Metformin Targets Mitochondrial Electron Transport to Reduce Air-Pollution-Induced Thrombosis
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    CD8+ T Cell Priming in Established Chronic Viral Infection Preferentially Directs Differentiation of Memory-like Cells for Sustained Immunity
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    Distinct Effector B Cells Induced by Unregulated Toll-like Receptor 7 Contribute to Pathogenic Responses in Systemic Lupus Erythematosus
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    ncbi.nlm.nih.gov/pmc/articles/PMC6217820/
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    The Majority of CD45– Ter119– CD31– Bone Marrow Cell Fraction Is of Hematopoietic Origin and Contains Erythroid and Lymphoid Progenitors
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    Complement C5a Fosters Squamous Carcinogenesis and Limits T Cell Response to Chemotherapy
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    MYC Interacts with the G9a Histone Methyltransferase to Drive Transcriptional Repression and Tumorigenesis
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    Muscle Satellite Cell Cross-Talk with a Vascular Niche Maintains Quiescence via VEGF and Notch Signaling
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    Intestinal Dysmotility Syndromes following Systemic Infection by Flaviviruses
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    Inheritance of CENP-A Nucleosomes during DNA Replication Requires HJURP
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    Immune Checkpoint Inhibition Overcomes ADCP-Induced Immunosuppression by Macrophages
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    Genetic Modulation of RNA Splicing with a CRISPR-Guided Cytidine Deaminase
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    Single-Cell Transcriptomic Analysis of Cardiac Differentiation from Human PSCs Reveals HOPX-Dependent Cardiomyocyte Maturation
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    An Endothelial-to-Adipocyte Extracellular Vesicle Axis Governed by Metabolic State
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    Sulfatide isoform pattern in cerebrospinal fluid discriminates progressive MS from relapsing‐remitting MS
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    CD8+ T Cell Activation Leads to Constitutive Formation of Liver Tissue-Resident Memory T Cells that Seed a Large and Flexible Niche in the Liver
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    Type I Interferon Receptor Signaling of Neurons and Astrocytes Regulates Microglia Activation during Viral Encephalitis
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    Secreted IgD Amplifies Humoral T Helper 2 Cell Responses by Binding Basophils via Galectin-9 and CD44
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    Regulatory T Cells Promote Macrophage Efferocytosis during Inflammation Resolution
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    B Cells Are the Dominant Antigen-Presenting Cells that Activate Naive CD4+ T Cells upon Immunization with a Virus-Derived Nanoparticle Antigen
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    The Mevalonate Pathway Is a Druggable Target for Vaccine Adjuvant Discovery
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    Subversion of Systemic Glucose Metabolism as a Mechanism to Support the Growth of Leukemia Cells
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    Epigenetic Restoration of Fetal-like IGF1 Signaling Inhibits Leukemia Stem Cell Activity
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    NONO Detects the Nuclear HIV Capsid to Promote cGAS-Mediated Innate Immune Activation
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    Vascular and Neurogenic Rejuvenation in Aging Mice by Modulation of ASM
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    A Metabolism-Based Quorum Sensing Mechanism Contributes to Termination of Inflammatory Responses
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    The BRCT Domains of the BRCA1 and BARD1 Tumor Suppressors Differentially Regulate Homology-Directed Repair and Stalled Fork Protection
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    Prospective Isolation and Characterization of Genetically and Functionally Distinct AML Subclones
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    Translational and HIF-1α-Dependent Metabolic Reprogramming Underpin Metabolic Plasticity and Responses to Kinase Inhibitors and Biguanides
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    Glutathione de novo synthesis but not recycling process coordinates with glutamine catabolism to control redox homeostasis and directs murine T cell differentiation
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    A Functionally Defined In Vivo Astrocyte Population Identified by c-Fos Activation in a Mouse Model of Multiple Sclerosis Modulated by S1P Signaling: Immediate-Early Astrocytes (ieAstrocytes)
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    LC3-Associated Phagocytosis in Myeloid Cells Promotes Tumor Immune Tolerance
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    Early Targeting of L-Selectin on Leukocytes Promotes Recovery after Spinal Cord Injury, Implicating Novel Mechanisms of Pathogenesis
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    SYK-CARD9 Signaling Axis Promotes Gut Fungi-Mediated Inflammasome Activation to Restrict Colitis and Colon Cancer
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    The Adaptor Protein CARD9 Protects against Colon Cancer by Restricting Mycobiota-Mediated Expansion of Myeloid-Derived Suppressor Cells
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    CD56 Expression Marks Human Group 2 Innate Lymphoid Cell Divergence from a Shared NK Cell and Group 3 Innate Lymphoid Cell Developmental Pathway
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    An Atypical Parvovirus Drives Chronic Tubulointerstitial Nephropathy and Kidney Fibrosis
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    A Bacterial Chromosome Structuring Protein Binds Overtwisted DNA to Stimulate Type II Topoisomerases and Enable DNA Replication
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    The Inhibitory Innate Immune Sensor NLRP12 Maintains a Threshold against Obesity by Regulating Gut Microbiota Homeostasis
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    A Membrane Potential- and Calpain-Dependent Reversal of Caspase-1 Inhibition Regulates Canonical NLRP3 Inflammasome
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    Tryparedoxin peroxidase-deficiency commits trypanosomes to ferroptosis-type cell death
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    The Ciliary Machinery Is Repurposed for T Cell Immune Synapse Trafficking of LCK
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    Disruption of the β1L Isoform of GABP Reverses Glioblastoma Replicative Immortality in a TERT Promoter Mutation-Dependent Manner
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    Mutant NPM1 Maintains the Leukemic State through HOX Expression
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    POLE3-POLE4 Is a Histone H3-H4 Chaperone that Maintains Chromatin Integrity during DNA Replication
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    MEF2B Instructs Germinal Center Development and Acts as an Oncogene in B Cell Lymphomagenesis
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    Identification of Chemotherapy-Induced Leukemic-Regenerating Cells Reveals a Transient Vulnerability of Human AML Recurrence
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    RANKL/RANK control Brca1 mutation-driven mammary tumors
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    β-Hydroxybutyrate Prevents Vascular Senescence through hnRNP A1-Mediated Upregulation of Oct4
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    Transcriptional and Translational Differences of Microglia from Male and Female Brains
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    ATR-Mediated Global Fork Slowing and Reversal Assist Fork Traverse and Prevent Chromosomal Breakage at DNA Interstrand Cross-Links
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    Insulin Receptor-Mediated Stimulation Boosts T Cell Immunity during Inflammation and Infection
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    Neurons under T Cell Attack Coordinate Phagocyte-Mediated Synaptic Stripping
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    Daily Onset of Light and Darkness Differentially Controls Hematopoietic Stem Cell Differentiation and Maintenance
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    Flow Cytometry of Mouse and Human Adipocytes for the Analysis of Browning and Cellular Heterogeneity
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    Self-Maintaining Gut Macrophages Are Essential for Intestinal Homeostasis
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    The Chemokine Receptor CCR8 Promotes the Migration of Dendritic Cells into the Lymph Node Parenchyma to Initiate the Allergic Immune Response
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    Lung γδ T Cells Mediate Protective Responses during Neonatal Influenza Infection that Are Associated with Type 2 Immunity
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    Gasdermin D Restrains Type I Interferon Response to Cytosolic DNA by Disrupting Ionic Homeostasis
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    A Map of Toll-like Receptor Expression in the Intestinal Epithelium Reveals Distinct Spatial, Cell Type-Specific, and Temporal Patterns
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    Non-canonical NF-κB Antagonizes STING Sensor-Mediated DNA Sensing in Radiotherapy
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    TBK1 Suppresses RIPK1-Driven Apoptosis and Inflammation during Development and in Aging
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    SIRT1 Activation Disrupts Maintenance of Myelodysplastic Syndrome Stem and Progenitor Cells by Restoring TET2 Function
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    Memory B Cells Activate Brain-Homing, Autoreactive CD4+ T Cells in Multiple Sclerosis
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    Quiescent Endothelial Cells Upregulate Fatty Acid β-Oxidation for Vasculoprotection via Redox Homeostasis
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    Alveolar Macrophages Provide an Early Mycobacterium tuberculosis Niche and Initiate Dissemination
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    A Chromatin Basis for Cell Lineage and Disease Risk in the Human Pancreas
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