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Aug 2021
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Interspecies Chimerism with Mammalian Pluripotent Stem Cells

1
1. scibot 12 Aug 2021
  
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  Plasmid_12259
  
  DOI: 10.1016/j.cell.2016.12.036
  
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sciencedirect.com/science/article/pii/S0092867416317524
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1. scibot 12 Aug 2021
  
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  plasmid_12259
  
  DOI: 10.7554/eLife.31023
  
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elifesciences.org/articles/31023
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Synchronized HIV assembly by tunable PIP2 changes reveals PIP2 requirement for stable Gag anchoring

1
1. scibot 12 Aug 2021
  
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  Addgene_12259
  
  DOI: 10.7554/eLife.25287
  
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elifesciences.org/articles/25287
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1. scibot 10 Aug 2021
  
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  Plasmid_12259
  
  DOI: 10.1016/j.celrep.2018.12.100
  
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sciencedirect.com/science/article/pii/S2211124718320758
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UBQLN4 Represses Homologous Recombination and Is Overexpressed in Aggressive Tumors

1
1. scibot 10 Aug 2021
  
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  Plasmid_12259
  
  DOI: 10.1016/j.cell.2018.11.024
  
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sciencedirect.com/science/article/pii/S0092867418315162
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1. scibot 10 Aug 2021
  
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  plasmid_12259
  
  DOI: 10.1016/j.immuni.2018.09.013
  
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sciencedirect.com/science/article/pii/S107476131830428X
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1
1. scibot 09 Aug 2021
  
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  Addgene_12259
  
  DOI: 10.7554/eLife.22416
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5340530/
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1. scibot 07 Aug 2021
  
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  Plasmid_12259
  
  DOI: 10.1016/j.celrep.2018.11.065
  
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sciencedirect.com/science/article/pii/S2211124718318412
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Epigenetic regulation of mammalian Hedgehog signaling to the stroma determines the molecular subtype of bladder cancer

1
1. scibot 07 Aug 2021
  
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  RRID:Addgene_12259
  
  DOI: 10.7554/eLife.43024
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6597241/
academic.oup.com academic.oup.com

Differential Actions of Estrogen Receptor α and β via Non-Genomic Signaling in Human Prostate Stem and Progenitor Cells

1
1. scibot 07 Aug 2021
  
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  RRID:Addgene_12259
  
  DOI: 10.1210/en.2019-00177
  
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academic.oup.com/endo/article/160/11/2692/5551999
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Large parental differences in chromatin organization in pancreatic beta cell line explaining diabetes susceptibility effects

1
1. scibot 06 Aug 2021
  
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  Addgene catalog no. 12259
  
  DOI: 10.1038/s41467-021-24635-2
  
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  RRID:Addgene_12259 RRIDCUR:Missing
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ncbi.nlm.nih.gov/pmc/articles/PMC8282625/
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ARv7 Represses Tumor-Suppressor Genes in Castration-Resistant Prostate Cancer

1
1. scibot 06 Aug 2021
  
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  Addgene_12259
  
  DOI: 10.1016/j.ccell.2019.01.008
  
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sciencedirect.com/science/article/pii/S153561081930042X
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Untitled document

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1. scibot 06 Aug 2021
  
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  Plasmid_12259
  
  DOI: 10.1016/j.cmet.2018.11.015
  
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sciencedirect.com/science/article/pii/S1550413118307344
elifesciences.org elifesciences.org

Subcellular drug targeting illuminates local kinase action

1
1. scibot 06 Aug 2021
  
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  RRID:Addgene_12259
  
  DOI: 10.7554/eLife.52220
  
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elifesciences.org/articles/52220
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Diarrheal pathogens trigger rapid evolution of the guanylate cyclase-C signaling axis in bats

1
1. scibot 06 Aug 2021
  
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  Addgene_12259
  
  DOI: 10.1016/j.chom.2021.07.005
  
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sciencedirect.com/science/article/pii/S1931312821003383
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The CD155/TIGIT axis promotes and maintains immune evasion in neoantigen-expressing pancreatic cancer

1
1. scibot 06 Aug 2021
  
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  RRID:Addgene_12259
  
  DOI: 10.1016/j.ccell.2021.07.007
  
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sciencedirect.com/science/article/pii/S1535610821003846
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Exercise-induced angiogenesis is dependent on metabolically primed ATF3/4+ endothelial cells

1
1. scibot 06 Aug 2021
  
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  Plasmid_12259
  
  DOI: 10.1016/j.cmet.2021.07.015
  
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sciencedirect.com/science/article/pii/S1550413121003314
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O-GlcNAc Transferase Links Glucose Metabolism to MAVS-Mediated Antiviral Innate Immunity

1
1. scibot 05 Aug 2021
  
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  addgene_12259
  
  DOI: 10.1016/j.chom.2018.11.001
  
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sciencedirect.com/science/article/pii/S1931312818305584
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The E3 ubiquitin ligase RNF10 modifies 40S ribosomal subunits of ribosomes compromised in translation

1
1. scibot 04 Aug 2021
  
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  Addgene_12259
  
  DOI: 10.1016/j.celrep.2021.109468
  
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sciencedirect.com/science/article/pii/S2211124721008913
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Untitled document

1
1. scibot 04 Aug 2021
  
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  Addgene_12259
  
  DOI: 10.1016/j.cell.2018.11.038
  
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  RRID:Addgene_12259
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sciencedirect.com/science/article/pii/S0092867418315630
www.mdpi.com www.mdpi.com

Phosphorylation of H3-Thr3 by Haspin Is Required for Primary Cilia Regulation

1
1. scibot 04 Aug 2021
  
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  Addgene_12259
  
  DOI: 10.3390/ijms22147753
  
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mdpi.com/1422-0067/22/14/7753/htm
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

1
1. scibot 04 Aug 2021
  
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  Addgene_12259
  
  DOI: 10.7554/eLife.25287
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5495570/
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Chemically modified guide RNAs enhance CRISPR-Cas13 knockdown in human cells

1
1. scibot 03 Aug 2021
  
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  Addgene 12259
  
  DOI: 10.1016/j.chembiol.2021.07.011
  
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  RRID:Addgene_12259 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S2451945621003512
jitc.biomedcentral.com jitc.biomedcentral.com

Untitled document

1
1. scibot 02 Aug 2021
  
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  plasmid_12259
  
  DOI: 10.1186/s40425-019-0575-3
  
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jitc.biomedcentral.com/articles/10.1186/s40425-019-0575-3
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Metabolically controlled histone H4K5 acylation/acetylation ratio drives BRD4 genomic distribution

1
1. scibot 01 Aug 2021
  
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  RRID:Addgene_12259
  
  DOI: 10.1016/j.celrep.2021.109460
  
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sciencedirect.com/science/article/pii/S2211124721008834
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DUX4-Induced Histone Variants H3.X and H3.Y Mark DUX4 Target Genes for Expression

1
1. scibot 01 Aug 2021
  
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  Addgene_12259
  
  DOI: 10.1016/j.celrep.2019.10.025
  
  Resource: RRID:Addgene_12259
  
  Curator: @ethanbadger
  
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  RRID:Addgene_12259 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124719313257
Jul 2021
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Enhancer Architecture and Essential Core Regulatory Circuitry of Chronic Lymphocytic Leukemia

1
1. scibot 31 Jul 2021
  
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  Addgene_12259
  
  DOI: 10.1016/j.ccell.2018.11.001
  
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sciencedirect.com/science/article/pii/S1535610818304835
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Untitled document

1
1. scibot 31 Jul 2021
  
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  RRID:Addgene_12259
  
  DOI: 10.1016/j.stem.2019.02.006
  
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  Curator: @ethanbadger
  
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  RRID:Addgene_12259 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1934590919300487
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Widespread and Functional RNA Circularization in Localized Prostate Cancer

1
1. scibot 31 Jul 2021
  
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  RRID:Addgene_12259
  
  DOI: 10.1016/j.cell.2019.01.025
  
  Resource: RRID:Addgene_12259
  
  Curator: @Naa003
  
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  RRID:Addgene_12259 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S0092867419300583
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

1
1. scibot 31 Jul 2021
  
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  RRID:Addgene_12259
  
  DOI: 10.7554/eLife.43511
  
  Resource: RRID:Addgene_12259
  
  Curator: @evieth
  
  SciCrunch record: RRID:Addgene_12259
  
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  RRID:Addgene_12259 RRIDCUR:Validated
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ncbi.nlm.nih.gov/pmc/articles/PMC6414201/
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TRIM32/USP11 Balances ARID1A Stability and the Oncogenic/Tumor-Suppressive Status of Squamous Cell Carcinoma

1
1. scibot 30 Jul 2021
  
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  RRID: Addgene_12259
  
  DOI: 10.1016/j.celrep.2019.12.017
  
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  Curator: @ethanbadger
  
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sciencedirect.com/science/article/pii/S2211124719316675
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Distinct Pathogenic Genes Causing Intellectual Disability and Autism Exhibit a Common Neuronal Network Hyperactivity Phenotype

1
1. scibot 30 Jul 2021
  
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  Addgene 12259
  
  DOI: 10.1016/j.celrep.2019.12.002
  
  Resource: RRID:Addgene_12259
  
  Curator: @ethanbadger
  
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sciencedirect.com/science/article/pii/S2211124719316419
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Molecular Basis for Autosomal-Dominant Renal Fanconi Syndrome Caused by HNF4A

1
1. scibot 30 Jul 2021
  
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  AddgeneCat# 12259
  
  DOI: 10.1016/j.celrep.2019.11.066
  
  Resource: RRID:Addgene_12259
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:Addgene_12259
  
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  RRID:Addgene_12259 RRIDCUR:Unrecognized
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sciencedirect.com/science/article/pii/S2211124719315578
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Low-Level Saturated Fatty Acid Palmitate Benefits Liver Cells by Boosting Mitochondrial Metabolism via CDK1-SIRT3-CPT2 Cascade

1
1. scibot 30 Jul 2021
  
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  RRID: Addgene_12259
  
  DOI: 10.1016/j.devcel.2019.11.012
  
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  Curator: @ethanbadger
  
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sciencedirect.com/science/article/pii/S1534580719309438
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Neuromodulator Signaling Bidirectionally Controls Vesicle Numbers in Human Synapses

1
1. scibot 30 Jul 2021
  
  in Public
  
  vsv-g expression vector (pMD2.G) (lentiviral helper plasmid)
  
  DOI: 10.1016/j.cell.2019.09.011
  
  Resource: RRID:Addgene_12259
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:Addgene_12259
  
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  RRIDCUR:Missing RRID:Addgene_12259
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sciencedirect.com/science/article/pii/S0092867419310177
www.nature.com www.nature.com

High-throughput genome-wide phenotypic screening via immunomagnetic cell sorting

1
1. scibot 30 Jul 2021
  
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  pMDG.2
  
  DOI: 10.1038/s41551-019-0454-8
  
  Resource: RRID:Addgene_12259
  
  Curator: @Naa003
  
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  RRIDCUR:Missing RRID:Addgene_12259
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nature.com/articles/s41551-019-0454-8
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mTORC1 Activation Requires DRAM-1 by Facilitating Lysosomal Amino Acid Efflux

1
1. scibot 30 Jul 2021
  
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  pMD2.G
  
  DOI: 10.1016/j.molcel.2019.07.021
  
  Resource: RRID:Addgene_12259
  
  Curator: @ethanbadger
  
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  RRIDCUR:Missing RRID:Addgene_12259
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sciencedirect.com/science/article/pii/S1097276519305519
link.springer.com link.springer.com

Untitled document

2
1. scibot 30 Jul 2021
  
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  plasmid_12259
  
  DOI: 10.1186/s40425-019-0575-3
  
  Resource: RRID:Addgene_12259
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_12259
  
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  RRID:Addgene_12259
2. scibot 27 Jul 2021
  
  in Public
  
  RRID:Addgene_12
  
  DOI: 10.1186/s40425-019-0575-3
  
  Resource: RRID:Addgene_12259
  
  Curator: @bandrow
  
  SciCrunch record: RRID:Addgene_12259
  
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  RRID:Addgene_12259 RRIDCUR:Unresolved
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link.springer.com/article/10.1186/s40425-019-0575-3
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The TIA1 RNA-Binding Protein Family Regulates EIF2AK2-Mediated Stress Response and Cell Cycle Progression

1
1. scibot 30 Jul 2021
  
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  Addgene_12259
  
  DOI: 10.1016/j.molcel.2018.01.011
  
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Suppression of Ribosomal Pausing by eIF5A Is Necessary to Maintain the Fidelity of Start Codon Selection

1
1. scibot 29 Jul 2021
  
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  Plasmid #12259
  
  DOI: 10.1016/j.celrep.2019.10.129
  
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Xenotransplanted Human Cortical Neurons Reveal Species-Specific Development and Functional Integration into Mouse Visual Circuits

1
1. scibot 29 Jul 2021
  
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  Addgene:12259
  
  DOI: 10.1016/j.neuron.2019.10.002
  
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sciencedirect.com/science/article/pii/S0896627319308505
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Recurrent SMARCB1 Mutations Reveal a Nucleosome Acidic Patch Interaction Site That Potentiates mSWI/SNF Complex Chromatin Remodeling

1
1. scibot 29 Jul 2021
  
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  RRID: Addgene_12259
  
  DOI: 10.1016/j.cell.2019.10.044
  
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NIX-Mediated Mitophagy Promotes Effector Memory Formation in Antigen-Specific CD8+ T Cells

1
1. scibot 29 Jul 2021
  
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  Addgene plasmid #12259
  
  DOI: 10.1016/j.celrep.2019.10.032
  
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sciencedirect.com/science/article/pii/S2211124719313324
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Sox2 and Klf4 as the Functional Core in Pluripotency Induction without Exogenous Oct4

1
1. scibot 29 Jul 2021
  
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  Addgene plasmid Cat# 12259
  
  DOI: 10.1016/j.celrep.2019.10.026
  
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sciencedirect.com/science/article/pii/S2211124719313269
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DUX4-Induced Histone Variants H3.X and H3.Y Mark DUX4 Target Genes for Expression

1
1. scibot 29 Jul 2021
  
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  Addgene12259
  
  DOI: 10.1016/j.celrep.2019.10.025
  
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Oct4-mediated reprogramming induces embryonic-like microRNA expression signatures in human fibroblasts

1
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  Addgene #12259
  
  DOI: 10.1038/s41598-019-52294-3
  
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nature.com/articles/s41598-019-52294-3
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Postmortem Cortex Samples Identify Distinct Molecular Subtypes of ALS: Retrotransposon Activation, Oxidative Stress, and Activated Glia

1
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  RRID:Addgene_12259
  
  DOI: 10.1016/j.celrep.2019.09.066
  
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Circular RNA circPICALM sponges miR-1265 to inhibit bladder cancer metastasis and influence FAK phosphorylation

1
1. scibot 29 Jul 2021
  
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  RRID:Addgene_12259
  
  DOI: 10.1016/j.ebiom.2019.08.074
  
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sciencedirect.com/science/article/pii/S2352396419305961
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Profilin-Mediated Actin Allocation Regulates the Growth of Epithelial Microvilli

1
1. scibot 29 Jul 2021
  
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  Addgene #12259
  
  DOI: 10.1016/j.cub.2019.08.051
  
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sciencedirect.com/science/article/pii/S0960982219311017
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Dynamic Incorporation of Histone H3 Variants into Chromatin Is Essential for Acquisition of Aggressive Traits and Metastatic Colonization

1
1. scibot 29 Jul 2021
  
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  Addgene12259
  
  DOI: 10.1016/j.ccell.2019.08.006
  
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Mitochondrial Reprogramming Underlies Resistance to BCL-2 Inhibition in Lymphoid Malignancies

1
1. scibot 29 Jul 2021
  
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  Addgene Plasmid #12259
  
  DOI: 10.1016/j.ccell.2019.08.005
  
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Natural Killer Cells Suppress T Cell-Associated Tumor Immune Evasion

1
1. scibot 29 Jul 2021
  
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  Addgene Plasmid:12259
  
  DOI: 10.1016/j.celrep.2019.08.017
  
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Identifying chemogenetic interactions from CRISPR screens with drugZ

1
1. scibot 29 Jul 2021
  
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  Addgene #12259
  
  DOI: 10.1186/s13073-019-0665-3
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6706933/
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TRPML1 Promotes Protein Homeostasis in Melanoma Cells by Negatively Regulating MAPK and mTORC1 Signaling

1
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  RRID:Addgene_12259
  
  DOI: 10.1016/j.celrep.2019.07.086
  
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sciencedirect.com/science/article/pii/S2211124719310022
www.embopress.org www.embopress.org

A genome‐wide screen identifies IRF2 as a key regulator of caspase‐4 in human cells

1
1. scibot 29 Jul 2021
  
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  Addgene plasmids #12259
  
  DOI: 10.15252/embr.201948235
  
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embopress.org/doi/full/10.15252/embr.201948235
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Essential thrombocytosis attributed to <Emphasis Type="Italic">JAK2</Emphasis>-T875N germline mutation

1
1. scibot 29 Jul 2021
  
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  RRID:Addgene 12259
  
  DOI: 10.1007/s12185-019-02725-8
  
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A Non-canonical Role of YAP/TEAD Is Required for Activation of Estrogen-Regulated Enhancers in Breast Cancer

1
1. scibot 29 Jul 2021
  
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  Plasmid ID: #12259
  
  DOI: 10.1016/j.molcel.2019.06.010
  
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Augmenting Immunotherapy Impact by Lowering Tumor TNF Cytotoxicity Threshold

1
1. scibot 29 Jul 2021
  
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  RRID:Addgene_12259
  
  DOI: 10.1016/j.cell.2019.06.014
  
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sciencedirect.com/science/article/pii/S0092867419306774
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PCIF1 Catalyzes m6Am mRNA Methylation to Regulate Gene Expression

1
1. scibot 29 Jul 2021
  
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  RRID: Addgene_12259
  
  DOI: 10.1016/j.molcel.2019.05.030
  
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sciencedirect.com/science/article/pii/S1097276519304022
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Genomic and Transcriptomic Determinants of Therapy Resistance and Immune Landscape Evolution during Anti-EGFR Treatment in Colorectal Cancer

1
1. scibot 29 Jul 2021
  
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  RRID:Addgene_12259
  
  DOI: 10.1016/j.ccell.2019.05.013
  
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BACH1 Stabilization by Antioxidants Stimulates Lung Cancer Metastasis

1
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  RRID: Addgene_12259
  
  DOI: 10.1016/j.cell.2019.06.005
  
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sciencedirect.com/science/article/pii/S0092867419306336
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p63 and SOX2 Dictate Glucose Reliance and Metabolic Vulnerabilities in Squamous Cell Carcinomas

1
1. scibot 29 Jul 2021
  
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  pMD2-VSVG
  
  DOI: 10.1016/j.celrep.2019.07.027
  
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sciencedirect.com/science/article/pii/S2211124719309246
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Untitled document

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  plasmid_12259
  
  DOI: 10.1038/s41421-018-0068-4
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6312541/
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Untitled document

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  RRID:Addgene_12259
  
  DOI: 10.1016/j.neo.2019.02.005
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6426874/
www.biorxiv.org www.biorxiv.org

Efficient and robust NK-Cell transduction with Baboon Envelope pseudotyped lentivector: a major tool for immunotherapy

1
1. scibot 29 Jul 2021
  
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  RRID:Addgene_12259
  
  DOI: 10.1101/625285
  
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biorxiv.org/content/10.1101/625285v1
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Untitled document

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  DOI: 10.1523/ENEURO.0135-18.2018
  
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eneuro.org/content/5/5/ENEURO.0135-18.2018
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Longitudinal Analysis of the Human B Cell Response to Ebola Virus Infection

1
1. scibot 28 Jul 2021
  
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  RRID:Addgene_12259
  
  DOI: 10.1016/j.cell.2019.04.036
  
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elifesciences.org elifesciences.org

CCL5 promotes breast cancer recurrence through macrophage recruitment in residual tumors

1
1. scibot 28 Jul 2021
  
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  RRID:Addgene_ 12259
  
  DOI: 10.7554/eLife.43653
  
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elifesciences.org/articles/43653
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Targeting an RNA-Binding Protein Network in Acute Myeloid Leukemia

1
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  Addgene: 12259
  
  DOI: 10.1016/j.ccell.2019.01.010
  
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Inflammatory Cytokine TNFα Promotes the Long-Term Expansion of Primary Hepatocytes in 3D Culture

1
1. scibot 28 Jul 2021
  
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  12259
  
  DOI: 10.1016/j.cell.2018.11.012
  
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www.jneurosci.org www.jneurosci.org

Calcium Channel Subunit α2δ4 Is Regulated by Early Growth Response 1 and Facilitates Epileptogenesis

1
1. scibot 28 Jul 2021
  
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  pMD2.G
  
  DOI: 10.1523/JNEUROSCI.1731-18.2019
  
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jneurosci.org/content/39/17/3175
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Deubiquitinases Maintain Protein Homeostasis and Survival of Cancer Cells upon Glutathione Depletion

1
1. scibot 28 Jul 2021
  
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  Addgene #12259
  
  DOI: 10.1016/j.cmet.2019.01.020
  
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sciencedirect.com/science/article/pii/S1550413119300208
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O-GlcNAc Transferase Suppresses Inflammation and Necroptosis by Targeting Receptor-Interacting Serine/Threonine-Protein Kinase 3

1
1. scibot 28 Jul 2021
  
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  Addgene#12259
  
  DOI: 10.1016/j.immuni.2019.01.007
  
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sciencedirect.com/science/article/pii/S1074761319300305
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Id1 Ablation Protects Hematopoietic Stem Cells from Stress-Induced Exhaustion and Aging

1
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  Addgene_12259
  
  DOI: 10.1016/j.stem.2018.06.001
  
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sciencedirect.com/science/article/pii/S1934590918302832
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Untitled document

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  DOI: 10.1016/j.neo.2019.02.005
  
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Epigenetic Silencing of CDR1as Drives IGF2BP3-Mediated Melanoma Invasion and Metastasis

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Defining HLA-II Ligand Processing and Binding Rules with Mass Spectrometry Enhances Cancer Epitope Prediction

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Mapping Cellular Reprogramming via Pooled Overexpression Screens with Paired Fitness and Single-Cell RNA-Sequencing Readout

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  DOI: 10.1016/j.cels.2018.10.008
  
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Oxidative Stress in Cells with Extra Centrosomes Drives Non-Cell-Autonomous Invasion

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Plasminogen Activator Inhibitor-1 Promotes the Recruitment and Polarization of Macrophages in Cancer

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Activation of miR-21-Regulated Pathways in Immune Aging Selects against Signatures Characteristic of Memory T Cells

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Transmembrane Protease TMPRSS11B Promotes Lung Cancer Growth by Enhancing Lactate Export and Glycolytic Metabolism

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Interactome and Proteome Dynamics Uncover Immune Modulatory Associations of the Pathogen Sensing Factor cGAS

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Nucleosome Turnover Regulates Histone Methylation Patterns over the Genome

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Untitled document

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Untitled document

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  DOI: 10.1016/j.stem.2017.08.018
  
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MYC Controls Human Pluripotent Stem Cell Fate Decisions through Regulation of Metabolic Flux

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  DOI: 10.1016/j.stem.2017.08.018
  
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Delivering progranulin to neuronal lysosomes protects against excitotoxicity

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Targeting an anchored phosphatase-deacetylase unit restores renal ciliary homeostasis

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Phosphorylated WNK kinase networks in recoded bacteria recapitulate physiological function

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A BLOC-1–AP-3 super-complex sorts a cis-SNARE complex into endosome-derived tubular transport carriers

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Binary pan-cancer classes with distinct vulnerabilities defined by pro- or anti-cancer YAP/TEAD activity

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Control of gasdermin D oligomerization and pyroptosis by the Ragulator-Rag-mTORC1 pathway

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ERAD components Derlin-1 and Derlin-2 are essential for postnatal brain development and motor function

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Mutants of human ACE2 differentially promote SARS-CoV and SARS-CoV-2 spike mediated infection

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BTN2A1, an immune checkpoint targeting Vγ9Vδ2 T cell cytotoxicity against malignant cells

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Active elimination of intestinal cells drives oncogenic growth in organoids

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Targeted protein degradation reveals a direct role of SPT6 in RNAPII elongation and termination

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The RAS GTPase RIT1 compromises mitotic fidelity through spindle assembly checkpoint suppression

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Role of the transcriptional regulator SP140 in resistance to bacterial infections via repression of type I interferons

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Regulation of NMDA receptor trafficking and gating by activity-dependent CaMKIIα phosphorylation of the GluN2A subunit

1
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Highly efficient manipulation of nervous system gene expression with NEPTUNE

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Multiplexed bioluminescence-mediated tracking of DNA double-strand break repairs in vitro and in vivo

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  DOI: 10.1038/s41596-021-00564-8
  
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BAP1/ASXL complex modulation regulates epithelial-mesenchymal transition during trophoblast differentiation and invasion

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Apoptotic cells represent a dynamic stem cell niche governing proliferation and tissue regeneration

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Jun 2021
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Revealing molecular pathways for cancer cell fitness through a genetic screen of the cancer translatome

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RAL GTPases mediate EGFR-driven intestinal stem cell proliferation and tumourigenesis

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1. scibot 26 Jun 2021
  
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Co-occurring gain-of-function mutations in HER2 and HER3 modulate HER2/HER3 activation, oncogenesis, and HER2 inhibitor sensitivity

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HepaCAM controls astrocyte self-organization and coupling

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  DOI: 10.1016/j.neuron.2021.05.025
  
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The pluripotent stem cell-specific transcript ESRG is dispensable for human pluripotency

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Positive feedback between the T cell kinase Zap70 and its substrate LAT acts as a clustering-dependent signaling switch

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Expansion of tumor-associated Treg cells upon disruption of a CTLA-4-dependent feedback loop

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Budding epithelial morphogenesis driven by cell-matrix versus cell-cell adhesion

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NADK is activated by oncogenic signaling to sustain pancreatic ductal adenocarcinoma

1
1. scibot 17 Jun 2021
  
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  DOI: 10.1016/j.celrep.2021.109238
  
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Phenotypic plasticity underlies local invasion and distant metastasis in colon cancer

1
1. scibot 17 Jun 2021
  
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  plasmid_12259
  
  DOI: 10.7554/eLife.61461
  
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Tailored generation of insulin producing cells from canine mesenchymal stem cells derived from bone marrow and adipose tissue

1
1. scibot 17 Jun 2021
  
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  DOI: 10.1038/s41598-021-91774-3
  
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Garcinia cambogia attenuates adipogenesis by affecting CEBPB and SQSTM1/p62-mediated selective autophagic degradation of KLF3 through RPS6KA1 and STAT3 suppression

1
1. scibot 17 Jun 2021
  
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  DOI: 10.1080/15548627.2021.1936356
  
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Protocol to establish a lung adenocarcinoma immunotherapy allograft mouse model with FACS and immunofluorescence-based analysis of tumor response

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Evaluation of glycolytic rates in human hematopoietic stem/progenitor cells after target gene depletion

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TMBIM1 is an inhibitor of adipogenesis and its depletion promotes adipocyte hyperplasia and improves obesity-related metabolic disease

1
1. scibot 12 Jun 2021
  
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Single-cell lineage tracing of metastatic cancer reveals selection of hybrid EMT states

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Tight nanoscale clustering of Fcγ receptors using DNA origami promotes phagocytosis

2
1. scibot 11 Jun 2021
  
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DMA-tudor interaction modules control the specificity of in vivo condensates

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Reprogramming an energetic AKT-PAK5 axis boosts axon energy supply and facilitates neuron survival and regeneration after injury and ischemia

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Pericentromeric Satellite III transcripts induce etoposide resistance

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May 2021
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Peptide-tiling screens of cancer drivers reveal oncogenic protein domains and associated peptide inhibitors

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Lipolysis drives expression of the constitutively active receptor GPR3 to induce adipose thermogenesis

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1. scibot 28 May 2021
  
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A phenotypically supervised single-cell analysis protocol to study within-cell-type heterogeneity of cultured mammalian cells

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SAM homeostasis is regulated by CFIm-mediated splicing of MAT2A

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Neuron and astrocyte aggregation and sorting in three-dimensional neuronal constructs

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  DOI: 10.1038/s42003-021-02104-2
  
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The Lysine Methylase SMYD3 Modulates Mesendodermal Commitment during Development

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Adhesion-mediated mechanosignaling forces mitohormesis

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1. scibot 21 May 2021
  
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NOX4 links metabolic regulation in pancreatic cancer to endoplasmic reticulum redox vulnerability and dependence on PRDX4

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Cargo receptor-assisted endoplasmic reticulum export of pathogenic α1-antitrypsin polymers

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In vivo CRISPR screening for novel noncoding RNA functional targets in glioblastoma models

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CD47 Ligation Repositions the Inhibitory Receptor SIRPA to Suppress Integrin Activation and Phagocytosis

2
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Caspase-1 Engages Full-Length Gasdermin D through Two Distinct Interfaces That Mediate Caspase Recruitment and Substrate Cleavage

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Rab34 GTPase mediates ciliary membrane formation in the intracellular ciliogenesis pathway

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Minimized combinatorial CRISPR screens identify genetic interactions in autophagy

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  DOI: 10.1093/nar/gkab309
  
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academic.oup.com/nar/advance-article/doi/10.1093/nar/gkab309/6270805
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The oncogenic E3 ligase TRIP12 suppresses epithelial–mesenchymal transition (EMT) and mesenchymal traits through ZEB1/2

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Assessing the Association of Mitochondrial Function and Inflammasome Activation in Murine Macrophages Exposed to Select Mitotoxic Tri-Organotin Compounds

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Targeting SUMOylation dependency in human cancer stem cells through a unique SAE2 motif revealed by chemical genomics

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p53 mediates target gene association with nuclear speckles for amplified RNA expression

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  DOI: 10.1016/j.molcel.2021.03.006
  
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Systematic Functional Analysis of SARS-CoV-2 Proteins Uncovers Viral Innate Immune Antagonists and Remaining Vulnerabilities

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FEZ1 forms complexes with CRMP1 and DCC to regulate axon and dendrite development

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  DOI: 10.1523/ENEURO.0193-20.2021
  
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eneuro.org/content/8/2/ENEURO.0193-20.2021
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Multiple interactions of the oncoprotein transcription factor MYC with the SWI/SNF chromatin remodeler

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  DOI: 10.1038/s41388-021-01804-7
  
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Calcitriol increases frataxin levels and restores mitochondrial function in cell models of Friedreich Ataxia

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  DOI: 10.1042/BCJ20200331
  
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Selective Translation of Cell Fate Regulators Mediates Tolerance to Broad Oncogenic Stress

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The Rational Development of CD133-Targeting Immunotherapies for Glioblastoma

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Amino Acids Enhance Polyubiquitination of Rheb and Its Binding to mTORC1 by Blocking Lysosomal ATXN3 Deubiquitinase Activity

1
1. scibot 07 May 2021
  
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  plasmid_12259
  
  DOI: 10.1016/j.molcel.2020.10.004
  
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Proteasome-Bound UCH37/UCHL5 Debranches Ubiquitin Chains to Promote Degradation

1
1. scibot 07 May 2021
  
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  Plasmid_12259
  
  DOI: 10.1016/j.molcel.2020.10.017
  
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RNF126-Mediated Reubiquitination Is Required for Proteasomal Degradation of p97-Extracted Membrane Proteins

1
1. scibot 07 May 2021
  
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  Addgene_12259
  
  DOI: 10.1016/j.molcel.2020.06.023
  
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HLTF Promotes Fork Reversal, Limiting Replication Stress Resistance and Preventing Multiple Mechanisms of Unrestrained DNA Synthesis

1
1. scibot 07 May 2021
  
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  RRID:Addgene_12259
  
  DOI: 10.1016/j.molcel.2020.04.031
  
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Targeted delivery of siRNAs against hepatocellular carcinoma-related genes by a galactosylated polyaspartamide copolymer

1
1. scibot 07 May 2021
  
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  plasmid_12259
  
  DOI: 10.1016/j.jconrel.2020.11.020
  
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Genome-wide Screens Identify Lineage- and Tumor-Specific Genes Modulating MHC-I- and MHC-II-Restricted Immunosurveillance of Human Lymphomas

1
1. scibot 07 May 2021
  
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  Addgene_12259
  
  DOI: 10.1016/j.immuni.2020.11.002
  
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Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains

1
1. scibot 06 May 2021
  
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  Addgene_12259
  
  DOI: 10.1016/j.molcel.2021.04.012
  
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A Single-Cell Transcriptomic Atlas of Human Skin Aging

1
1. scibot 05 May 2021
  
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  plasmid_12259
  
  DOI: 10.1016/j.devcel.2020.11.002
  
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Mechanical Tension Promotes Formation of Gastrulation-like Nodes and Patterns Mesoderm Specification in Human Embryonic Stem Cells

1
1. scibot 05 May 2021
  
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  RRID:Addgene_12259
  
  DOI: 10.1016/j.devcel.2020.10.015
  
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A Membrane-Tethered Ubiquitination Pathway Regulates Hedgehog Signaling and Heart Development

1
1. scibot 05 May 2021
  
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  Addgene_12259
  
  DOI: 10.1016/j.devcel.2020.08.012
  
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An Excitable Ras/PI3K/ERK Signaling Network Controls Migration and Oncogenic Transformation in Epithelial Cells

1
1. scibot 05 May 2021
  
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  Plasmid_12259
  
  DOI: 10.1016/j.devcel.2020.08.001
  
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Mitotic ER Exit Site Disassembly and Reassembly Are Regulated by the Phosphorylation Status of TANGO1

1
1. scibot 05 May 2021
  
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  RRID:Addgene_12259
  
  DOI: 10.1016/j.devcel.2020.07.017
  
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Activation of HERV-K(HML-2) disrupts cortical patterning and neuronal differentiation by increasing NTRK3

1
1. scibot 05 May 2021
  
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  plasmid_12259
  
  DOI: 10.1016/j.stem.2021.04.009
  
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Direct visualization of epithelial microvilli biogenesis

1
1. scibot 05 May 2021
  
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  Addgene_12259
  
  DOI: 10.1016/j.cub.2021.04.012
  
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Ligand Binding to the Collagen VI Receptor Triggers a Talin-to-RhoA Switch that Regulates Receptor Endocytosis

1
1. scibot 04 May 2021
  
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  12259
  
  DOI: 10.1016/j.devcel.2020.04.015
  
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Targeting microRNA-mediated gene repression limits adipogenic conversion of skeletal muscle mesenchymal stromal cells

1
1. scibot 04 May 2021
  
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  Addgene_12259
  
  DOI: 10.1016/j.stem.2021.04.008
  
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Transient Primary Cilia Mediate Robust Hedgehog Pathway-Dependent Cell Cycle Control

1
1. scibot 01 May 2021
  
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  RRID:Addgene_12259
  
  DOI: 10.1016/j.cub.2020.05.004
  
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Apr 2021
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Tumor Reliance on Cytosolic versus Mitochondrial One-Carbon Flux Depends on Folate Availability

1
1. scibot 30 Apr 2021
  
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  Cat#: 12259
  
  DOI: 10.1016/j.cmet.2020.12.002
  
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Local Mitochondrial ATP Production Regulates Endothelial Fatty Acid Uptake and Transport

2
1. scibot 29 Apr 2021
  
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  Cat#12259
  
  DOI: 10.1016/j.cmet.2020.05.018
  
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2. scibot 29 Apr 2021
  
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  addgene_12259
  
  DOI: 10.1016/j.cmet.2020.05.018
  
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Discovery of cellular substrates of human RNA-decapping enzyme DCP2 using a stapled bicyclic peptide inhibitor

1
1. scibot 28 Apr 2021
  
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  Addgene Cat#12259
  
  DOI: 10.1016/j.chembiol.2020.12.003
  
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Transcriptional control of DNA repair networks by CDK7 regulates sensitivity to radiation in MYC-driven medulloblastoma

1
1. scibot 28 Apr 2021
  
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  Cat#12259
  
  DOI: 10.1016/j.celrep.2021.109013
  
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Inhibition of mitochondrial translation suppresses glioblastoma stem cell growth

1
1. scibot 28 Apr 2021
  
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  RRID:Addgene_12259
  
  DOI: 10.1016/j.celrep.2021.109024
  
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Colonic epithelial adaptation to EGFR-independent growth induces chromosomal instability and is accelerated by prior injury

1
1. scibot 27 Apr 2021
  
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  Addgene plasmid RRID# 12259
  
  DOI: 10.1016/j.neo.2021.03.010
  
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sciencedirect.com/science/article/pii/S1476558621000208
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A Method for Conditional Regulation of Protein Stability in Native or Near-Native Form

1
1. scibot 27 Apr 2021
  
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  Plasmid_12259
  
  DOI: 10.1016/j.chembiol.2020.09.004
  
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Illuminating Host-Mycobacterial Interactions with Genome-wide CRISPR Knockout and CRISPRi Screens

1
1. scibot 27 Apr 2021
  
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  Addgene_12259
  
  DOI: 10.1016/j.cels.2020.08.010
  
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Genetically engineered myeloid cells rebalance the core immune suppression program in metastasis

1
1. scibot 27 Apr 2021
  
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  RRID:Addgene_12259
  
  DOI: 10.1016/j.cell.2021.02.048
  
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A Structural Model of the Endogenous Human BAF Complex Informs Disease Mechanisms

1
1. scibot 24 Apr 2021
  
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  RRID: Addgene_12259
  
  DOI: 10.1016/j.cell.2020.09.051
  
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CD81 Controls Beige Fat Progenitor Cell Growth and Energy Balance via FAK Signaling

1
1. scibot 24 Apr 2021
  
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  Cat# 12259
  
  DOI: 10.1016/j.cell.2020.06.021
  
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p53 is a central regulator driving neurodegeneration caused by C9orf72 poly(PR)

1
1. scibot 24 Apr 2021
  
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  Addgene 12259
  
  DOI: 10.1016/j.cell.2020.12.025
  
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sciencedirect.com/science/article/pii/S0092867420317475
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High-Throughput Discovery and Characterization of Human Transcriptional Effectors

1
1. scibot 24 Apr 2021
  
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  RRID:Addgene_12259
  
  DOI: 10.1016/j.cell.2020.11.024
  
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sciencedirect.com/science/article/pii/S0092867420315415
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Defining the Teratoma as a Model for Multi-lineage Human Development

1
1. scibot 24 Apr 2021
  
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  Addgene_12259
  
  DOI: 10.1016/j.cell.2020.10.018
  
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sciencedirect.com/science/article/pii/S0092867420313817
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Neurons Release Serine to Support mRNA Translation in Pancreatic Cancer

1
1. scibot 24 Apr 2021
  
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  Addgene_12259
  
  DOI: 10.1016/j.cell.2020.10.016
  
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sciencedirect.com/science/article/pii/S0092867420313222
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Self-Reporting Transposons Enable Simultaneous Readout of Gene Expression and Transcription Factor Binding in Single Cells

1
1. scibot 24 Apr 2021
  
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  plasmid_12259
  
  DOI: 10.1016/j.cell.2020.06.037
  
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Type V Collagen in Scar Tissue Regulates the Size of Scar after Heart Injury

1
1. scibot 24 Apr 2021
  
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  Addgene_12259
  
  DOI: 10.1016/j.cell.2020.06.030
  
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A Genetic Map of the Response to DNA Damage in Human Cells

2
1. scibot 23 Apr 2021
  
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  Addgene Cat# 12259
  
  DOI: 10.1016/j.cell.2020.05.040
  
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2. scibot 23 Apr 2021
  
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  Addgene_12259
  
  DOI: 10.1016/j.cell.2020.05.040
  
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Cancer Burden Is Controlled by Mural Cell-β3-Integrin Regulated Crosstalk with Tumor Cells

1
1. scibot 23 Apr 2021
  
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  CAT#12259
  
  DOI: 10.1016/j.cell.2020.02.003
  
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MDMX acts as a pervasive preleukemic-to-acute myeloid leukemia transition mechanism

1
1. scibot 22 Apr 2021
  
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  12259
  
  DOI: 10.1016/j.ccell.2021.02.006
  
  Resource: RRID:Addgene_12259
  
  Curator: @Naa003
  
  SciCrunch record: RRID:Addgene_12259
  
  What is this?
  
  RRIDCUR:Missing RRID:Addgene_12259
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RRID:Addgene_12259

RRIDCUR:Missing

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scibot

URL

sciencedirect.com/science/article/pii/S1535610821001082
www.sciencedirect.com www.sciencedirect.com

YTHDF3 Induces the Translation of m6A-Enriched Gene Transcripts to Promote Breast Cancer Brain Metastasis

1
1. scibot 22 Apr 2021
  
  in Public
  
  Cat# 12259
  
  DOI: 10.1016/j.ccell.2020.10.004
  
  Resource: RRID:Addgene_12259
  
  Curator: @Naa003
  
  SciCrunch record: RRID:Addgene_12259
  
  What is this?
  
  RRIDCUR:Missing RRID:Addgene_12259
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RRID:Addgene_12259

RRIDCUR:Missing

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scibot

URL

sciencedirect.com/science/article/pii/S1535610820304980
www.sciencedirect.com www.sciencedirect.com

Cholesterol Pathway Inhibition Induces TGF-β Signaling to Promote Basal Differentiation in Pancreatic Cancer

1
1. scibot 22 Apr 2021
  
  in Public
  
  plasmid_12259
  
  DOI: 10.1016/j.ccell.2020.08.015
  
  Resource: RRID:Addgene_12259
  
  Curator: @Naa003
  
  SciCrunch record: RRID:Addgene_12259
  
  What is this?
  
  RRIDCUR:Validated RRID:Addgene_12259
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RRID:Addgene_12259

RRIDCUR:Validated

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URL

sciencedirect.com/science/article/pii/S1535610820304268
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The bone microenvironment increases phenotypic plasticity of ER+ breast cancer cells

2
1. scibot 20 Apr 2021
  
  in Public
  
  RRID:_Addgene_12259
  
  DOI: 10.1016/j.devcel.2021.03.008
  
  Resource: RRID:Addgene_12259
  
  Curator: @Naa003
  
  SciCrunch record: RRID:Addgene_12259
  
  Curator comments: pMD2.G
  
  What is this?
  
  RRIDCUR:Unresolved RRID:Addgene_12259 RRIDCUR:SyntaxError
2. scibot 20 Apr 2021
  
  in Public
  
  Plasmid_12259
  
  DOI: 10.1016/j.devcel.2021.03.008
  
  Resource: RRID:Addgene_12259
  
  Curator: @Naa003
  
  SciCrunch record: RRID:Addgene_12259
  
  What is this?
  
  RRIDCUR:Validated RRID:Addgene_12259
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RRID:Addgene_12259

RRIDCUR:Validated

RRIDCUR:Unresolved

RRIDCUR:SyntaxError

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scibot

URL

sciencedirect.com/science/article/pii/S1534580721002057
www.sciencedirect.com www.sciencedirect.com

Lipid-mediated motor-adaptor sequestration impairs axonal lysosome delivery leading to autophagic stress and dystrophy in Niemann-Pick type C

1
1. scibot 20 Apr 2021
  
  in Public
  
  plasmid_12259
  
  DOI: 10.1016/j.devcel.2021.03.032
  
  Resource: RRID:Addgene_12259
  
  Curator: @Naa003
  
  SciCrunch record: RRID:Addgene_12259
  
  What is this?
  
  RRIDCUR:Validated RRID:Addgene_12259
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RRID:Addgene_12259

RRIDCUR:Validated

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scibot

URL

sciencedirect.com/science/article/pii/S1534580721003075
www.sciencedirect.com www.sciencedirect.com

Selective Inhibition of STRN3-Containing PP2A Phosphatase Restores Hippo Tumor-Suppressor Activity in Gastric Cancer

1
1. scibot 17 Apr 2021
  
  in Public
  
  Cat# 12259
  
  DOI: 10.1016/j.ccell.2020.05.019
  
  Resource: RRID:Addgene_12259
  
  Curator: @Naa003
  
  SciCrunch record: RRID:Addgene_12259
  
  What is this?
  
  RRIDCUR:Missing RRID:Addgene_12259
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RRID:Addgene_12259

RRIDCUR:Missing

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scibot

URL

sciencedirect.com/science/article/pii/S1535610820302695
www.sciencedirect.com www.sciencedirect.com

MAX Functions as a Tumor Suppressor and Rewires Metabolism in Small Cell Lung Cancer

1
1. scibot 17 Apr 2021
  
  in Public
  
  Cat# 12259
  
  DOI: 10.1016/j.ccell.2020.04.016
  
  Resource: RRID:Addgene_12259
  
  Curator: @Naa003
  
  SciCrunch record: RRID:Addgene_12259
  
  What is this?
  
  RRIDCUR:Missing RRID:Addgene_12259
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RRID:Addgene_12259

RRIDCUR:Missing

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scibot

URL

sciencedirect.com/science/article/pii/S1535610820302154
www.sciencedirect.com www.sciencedirect.com

Targeting FTO Suppresses Cancer Stem Cell Maintenance and Immune Evasion

1
1. scibot 17 Apr 2021
  
  in Public
  
  RRID:Addgene_12259
  
  DOI: 10.1016/j.ccell.2020.04.017
  
  Resource: RRID:Addgene_12259
  
  Curator: @Naa003
  
  SciCrunch record: RRID:Addgene_12259
  
  What is this?
  
  RRIDCUR:Validated RRID:Addgene_12259
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RRID:Addgene_12259

RRIDCUR:Validated

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scibot

URL

sciencedirect.com/science/article/pii/S1535610820302166
www.sciencedirect.com www.sciencedirect.com

SETD5-Coordinated Chromatin Reprogramming Regulates Adaptive Resistance to Targeted Pancreatic Cancer Therapy

1
1. scibot 17 Apr 2021
  
  in Public
  
  Addgene_12259
  
  DOI: 10.1016/j.ccell.2020.04.014
  
  Resource: RRID:Addgene_12259
  
  Curator: @Naa003
  
  SciCrunch record: RRID:Addgene_12259
  
  What is this?
  
  RRIDCUR:Validated RRID:Addgene_12259
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RRID:Addgene_12259

RRIDCUR:Validated

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1535610820302130

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