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387 Matching Annotations

Apr 2023
52.53.155.43 52.53.155.43

Evolution of promoter-proximal pausing enabled a new layer of transcription control

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1. scibot 11 Apr 2023
  
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  DOI: 10.1101/2023.02.19.529146
  
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52.53.155.43/3c5d712daefd9b4515c968980af0bacbaf86aeb6/2023.02.19.529146v1.full-html.html
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Histone phosphorylation integrates the hepatic glucagon-PKA-CREB gluconeogenesis program in response to fasting

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1. scibot 06 Apr 2023
  
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  DOI: 10.1016/j.molcel.2023.02.007
  
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sciencedirect.com/science/article/pii/S1097276523001028
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Escape from oncogene-induced senescence is controlled by POU2F2 and memorized by chromatin scars

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1. scibot 06 Apr 2023
  
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  DOI: 10.1016/j.xgen.2023.100293
  
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sciencedirect.com/science/article/pii/S2666979X23000599
Mar 2023
52.53.155.43 52.53.155.43

v1_covered (2)-html.html

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1. scibot 31 Mar 2023
  
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  RRID:AB_10544537
  
  DOI: 10.21203/rs.3.rs-2679520/v1
  
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52.53.155.43/71d28ab512c8a7f856b6488255deb4243c9223cd/v1_covered (2)-html.html
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Multiplex imaging of breast cancer lymph node metastases identifies prognostic single-cell populations independent of clinical classifiers

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1. scibot 18 Mar 2023
  
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  DOI: 10.1016/j.xcrm.2023.100977
  
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sciencedirect.com/science/article/pii/S2666379123000836
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Linking chromatin acylation mark-defined proteome and genome in living cells

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1. scibot 03 Mar 2023
  
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  DOI: 10.1016/j.cell.2023.02.007
  
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sciencedirect.com/science/article/pii/S0092867423001095
Feb 2023
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Beta-coronaviruses exploit cellular stress responses by modulating TFEB and TFE3 activity

1
1. scibot 23 Feb 2023
  
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  DOI: 10.1016/j.isci.2023.106169
  
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sciencedirect.com/science/article/pii/S2589004223002468
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Loss of IGFBP2 mediates alveolar type 2 cell senescence and promotes lung fibrosis

1
1. scibot 17 Feb 2023
  
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  DOI: 10.1016/j.xcrm.2023.100945
  
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sciencedirect.com/science/article/pii/S266637912300037X
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β-Hydroxybutyrate preferentially enhances neuron over astrocyte respiration while signaling cellular quiescence

1
1. scibot 03 Feb 2023
  
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  DOI: 10.1016/j.mito.2022.12.004
  
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sciencedirect.com/science/article/pii/S1567724922001088
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D-2-hydroxyglutarate dehydrogenase governs adult neural stem cell activation and promotes histone acetylation via ATP-citrate lyase

1
1. scibot 02 Feb 2023
  
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  DOI: 10.1016/j.celrep.2023.112067
  
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sciencedirect.com/science/article/pii/S2211124723000785
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Numb/Parkin-directed mitochondrial fitness governs cancer cell fate via metabolic regulation of histone lactylation

1
1. scibot 02 Feb 2023
  
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  DOI: 10.1016/j.celrep.2023.112033
  
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sciencedirect.com/science/article/pii/S221112472300044X
Jan 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Cancer stem cells, not bulk tumor cells, determine mechanisms of resistance to SMO inhibitors

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1. scibot 25 Jan 2023
  
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  RRID:AB_10544537
  
  DOI: 10.1158/2767-9764.crc-22-0124
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9853917/
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Intersection of immune and oncometabolic pathways drives cancer hyperprogression during immunotherapy

1
1. scibot 19 Jan 2023
  
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  RRID:AB_10544537
  
  DOI: 10.1016/j.ccell.2022.12.008
  
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sciencedirect.com/science/article/pii/S1535610822005943
www.embopress.org www.embopress.org

Jacob-induced transcriptional inactivation of CREB promotes Aβ-induced synapse loss in Alzheimer's disease

1
1. scibot 08 Jan 2023
  
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  RRID:AB_10544537
  
  DOI: 10.15252/embj.2022112453
  
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embopress.org/doi/full/10.15252/embj.2022112453
www.mdpi.com www.mdpi.com

Remarkable Synergy When Combining EZH2 Inhibitors with YM155 Is H3K27me3-Independent

1
1. scibot 04 Jan 2023
  
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  RRID:AB_10544537
  
  DOI: 10.3390/cancers15010208
  
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mdpi.com/2072-6694/15/1/208
Dec 2022
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β-hydroxybutyrate inhibits ferroptosis-mediated pancreatic damage in acute liver failure through the increase of H3K9bhb

1
1. scibot 24 Dec 2022
  
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  RRID:AB_10544537
  
  DOI: 10.1016/j.celrep.2022.111847
  
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sciencedirect.com/science/article/pii/S2211124722017399
aacrjournals.org aacrjournals.org

Loss of epigenetic regulation disrupts lineage integrity, induces aberrant alveogenesis and promotes breast cancer

1
1. scibot 03 Dec 2022
  
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  RRID:AB_10544537
  
  DOI: 10.1158/2159-8290.CD-21-0865
  
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aacrjournals.org/cancerdiscovery/article/12/12/2930/711188/Loss-of-Epigenetic-Regulation-Disrupts-Lineage
Nov 2022
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Autophagy promotes cell survival by maintaining NAD levels

1
1. scibot 22 Nov 2022
  
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  RRID:AB_10544537
  
  DOI: 10.1016/j.devcel.2022.10.008
  
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sciencedirect.com/science/article/pii/S1534580722007602
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Transcription factors TEAD2 and E2A globally repress acetyl-CoA synthesis to promote tumorigenesis

1
1. scibot 18 Nov 2022
  
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  RRID:AB_10544537
  
  DOI: 10.1016/j.molcel.2022.10.027
  
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sciencedirect.com/science/article/pii/S1097276522010553
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Molecular classification and biomarkers of clinical outcome in breast ductal carcinoma in situ: Analysis of TBCRC 038 and RAHBT cohorts

1
1. scibot 18 Nov 2022
  
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  RRID:AB_10544537
  
  DOI: 10.1016/j.ccell.2022.10.021
  
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sciencedirect.com/science/article/pii/S1535610822005128
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Identification of phosphorylation site on PARP1 mediating its cytosolic translocation in virus-infected HeLa cells

1
1. scibot 17 Nov 2022
  
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  DOI: 10.1016/j.xpro.2022.101808
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9640338/
Oct 2022
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Spatial epitope barcoding reveals clonal tumor patch behaviors

1
1. scibot 16 Oct 2022
  
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  DOI: 10.1016/j.ccell.2022.09.014
  
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sciencedirect.com/science/article/pii/S1535610822004433
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Deficiency of peroxisomal NUDT7 stimulates de novo lipogenesis in hepatocytes

1
1. scibot 04 Oct 2022
  
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  RRID:AB_10544537
  
  DOI: 10.1016/j.isci.2022.105135
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9523354/
Sep 2022
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Ral GTPases are critical regulators of spinal cord myelination and homeostasis

1
1. scibot 29 Sep 2022
  
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  RRID:AB_10544537
  
  DOI: 10.1016/j.celrep.2022.111413
  
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sciencedirect.com/science/article/pii/S2211124722012542
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MPS1 inhibition primes immunogenicity of KRAS-LKB1 mutant lung cancer

1
1. scibot 24 Sep 2022
  
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  RRID:AB_10544537
  
  DOI: 10.1016/j.ccell.2022.08.015
  
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sciencedirect.com/science/article/pii/S1535610822003798
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Confined migration induces heterochromatin formation and alters chromatin accessibility

1
1. scibot 22 Sep 2022
  
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  RRID:AB_10544537
  
  DOI: 10.1016/j.isci.2022.104978
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9474860/
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Targeting histone methylation to reprogram the transcriptional state that drives survival of drug-tolerant myeloid leukemia persisters

1
1. scibot 15 Sep 2022
  
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  RRID:AB_10544537
  
  DOI: 10.1016/j.isci.2022.105013
  
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sciencedirect.com/science/article/pii/S2589004222012858
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Ceramide induces macrophage migration inhibitory factor -mediated parthanatos in mouse neurons by increasing ROS levels

1
1. scibot 10 Sep 2022
  
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  DOI: 10.1016/j.neulet.2022.136862
  
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sciencedirect.com/science/article/pii/S0304394022004232
Aug 2022
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DPY30 acts as an ASH2L-specific stabilizer to stimulate the enzyme activity of MLL family methyltransferases on different substrates

1
1. scibot 30 Aug 2022
  
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  DOI: 10.1016/j.isci.2022.104948
  
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sciencedirect.com/science/article/pii/S2589004222012202
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Mitochondrial double-stranded RNAs govern the stress response in chondrocytes to promote osteoarthritis development

1
1. scibot 10 Aug 2022
  
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  DOI: 10.1016/j.celrep.2022.111178
  
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sciencedirect.com/science/article/pii/S2211124722009913
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CD24-Siglec axis is an innate immune checkpoint against metaflammation and metabolic disorder

1
1. scibot 04 Aug 2022
  
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  DOI: 10.1016/j.cmet.2022.07.005
  
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sciencedirect.com/science/article/pii/S1550413122003047
Jul 2022
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Skeletal progenitors preserve proliferation and self-renewal upon inhibition of mitochondrial respiration by rerouting the TCA cycle

1
1. scibot 30 Jul 2022
  
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  DOI: 10.1016/j.celrep.2022.111105
  
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sciencedirect.com/science/article/pii/S221112472200907X
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Mapping subcellular localizations of unannotated microproteins and alternative proteins with MicroID

1
1. scibot 30 Jul 2022
  
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  DOI: 10.1016/j.molcel.2022.06.035
  
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sciencedirect.com/science/article/pii/S1097276522006530
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Integrin β3 Promotes Resistance to EGFR-TKI in Non-Small-Cell Lung Cancer by Upregulating AXL through the YAP Pathway

1
1. scibot 12 Jul 2022
  
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  RRID:AB_10544537
  
  DOI: 10.3390/cells11132078
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9265629/
Jun 2022
52.53.155.43 52.53.155.43

cd-21-1022-html.html

3
1. scibot 30 Jun 2022
  
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  RRID:AB_10544537
  
  DOI: 10.1158/2159-8290.CD-21-1022
  
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Methionine oxidation activates pyruvate kinase M2 to promote pancreatic cancer metastasis

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Activation of STAT3 through combined SRC and EGFR signaling drives resistance to a mitotic kinesin inhibitor in glioblastoma

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Single-cell epigenetic analysis reveals principles of chromatin states in H3.3-K27M gliomas

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Protein interactome and cell-type expression analyses reveal that cytoplasmic FMR1-interacting protein 1 (CYFIP1), but not CYFIP2, associates with astrocytic focal adhesion

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Cancer Stem Cells, not Bulk Tumor Cells, Determine Mechanisms of Resistance to SMO Inhibitors

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High-intensity interval training remodels the proteome and acetylome of human skeletal muscle

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H3-K27M-mutant nucleosomes interact with MLL1 to shape the glioma epigenetic landscape

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WEE1 inhibition enhances the antitumor immune response to PD-L1 blockade by the concomitant activation of STING and STAT1 pathways in SCLC

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PAAN/MIF nuclease inhibition prevents neurodegeneration in Parkinson’s disease

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Cytoplasmic PARP1 links the genome instability to the inhibition of antiviral immunity through PARylating cGAS

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Hydroxysafflor Yellow A Blocks HIF-1α Induction of NOX2 and Protects ZO-1 Protein in Cerebral Microvascular Endothelium

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Multilayered omics reveal sex- and depot-dependent adipose progenitor cell heterogeneity

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Disease-associated KBTBD4 mutations in medulloblastoma elicit neomorphic ubiquitylation activity to promote CoREST degradation

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Lactate rewires lipid metabolism and sustains a metabolic-epigenetic axis in prostate cancer

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BPS Publications

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Mucus sialylation determines intestinal host-commensal homeostasis

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Setd2 determines distinct properties of intestinal ILC3 subsets to regulate intestinal immunity

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Fumarate inhibits PTEN to promote tumorigenesis and therapeutic resistance of type2 papillary renal cell carcinoma

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Cellular plasticity upon proton irradiation determines tumor cell radiosensitivity

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Unresolved stalled ribosome complexes restrict cell-cycle progression after genotoxic stress

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Tau nuclear translocation is a leading step in tau pathology process through P53 stabilization and nucleolar dispersion

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Lactic acid promotes PD-1 expression in regulatory T cells in highly glycolytic tumor microenvironments

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GSDMB is increased in IBD and regulates epithelial restitution/repair independent of pyroptosis

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TRIB3 is highly expressed in the adipose tissue of obese patients and is associated with insulin resistance

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KDM6B promotes activation of the oncogenic CDK4/6-pRB-E2F pathway by maintaining enhancer activity in MYCN-amplified neuroblastoma

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MATISSE: An analysis protocol for combining imaging mass cytometry with fluorescence microscopy to generate single-cell data

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Experiments from unfinished Registered Reports in the Reproducibility Project: Cancer Biology

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Reassessment of the proteomic composition and function of extracellular vesicles in the seminal plasma

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The Y14-p53 regulatory circuit in megakaryocyte differentiation and thrombocytopenia

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Reprogramming of H3K9bhb at regulatory elements is a key feature of fasting in the small intestine

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Single-cell transcriptomics reveals opposing roles of Shp2 in Myc-driven liver tumor cells and microenvironment

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Starvation induced autophagy promotes the progression of bladder cancer by LDHA mediated metabolic reprogramming

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Zinc-dependent histone deacetylases drive neutrophil extracellular trap formation and potentiate local and systemic inflammation

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Rapamycin targets STAT3 and impacts c-Myc to suppress tumor growth

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Cell geometry, signal dampening, and a bimodal transcriptional response underlie the spatial precision of an ERK-mediated embryonic induction

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Multiplexed imaging reveals an IFN-γ-driven inflammatory state in nivolumab-associated gastritis

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Proteomics reveal cap-dependent translation inhibitors remodel the translation machinery and translatome

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Long noncoding RNA lnc-POP1-1 upregulated by VN1R5 promotes cisplatin resistance in head and neck squamous cell carcinoma through interaction with MCM5

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Increased fidelity of protein synthesis extends lifespan

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Osteopontin regulates proliferation, migration, and survival of astrocytes depending on their activation phenotype

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Comparison of Histone H3K4me3 between IVF and ICSI Technologies and between Boy and Girl Offspring

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GAGE mediates radio resistance in cervical cancers via the regulation of chromatin accessibility

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Extracellular vesicle-based interorgan transport of mitochondria from energetically stressed adipocytes

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NAD+ supplement potentiates tumor-killing function by rescuing defective TUB-mediated NAMPT transcription in tumor-infiltrated T cells

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Spinal Nrf2 translocation may inhibit neuronal NF-κB activation and alleviate allodynia in a rat model of bone cancer pain

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Chemogenomics identifies acetyl-coenzyme A synthetase as a target for malaria treatment and prevention

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Non-canonical Activation of the DNA Sensing Adaptor STING by ATM and IFI16 Mediates NF-κB Signaling after Nuclear DNA Damage

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Rigidity controls human desmoplastic matrix anisotropy to enable pancreatic cancer cell spread via extracellular signal-regulated kinase 2

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Reprogramming of bivalent chromatin states in NRAS mutant melanoma suggests PRC2 inhibition as a therapeutic strategy

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Lysine acetylation restricts mutant IDH2 activity to optimize transformation in AML cells

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The Mediator subunit MED20 organizes the early adipogenic complex to promote development of adipose tissues and diet-induced obesity

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Global mapping of Salmonella enterica-host protein-protein interactions during infection

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T-cell receptor (TCR) signaling promotes the assembly of RanBP2/RanGAP1-SUMO1/Ubc9 nuclear pore subcomplex via PKC-θ-mediated phosphorylation of RanGAP1

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Deep spatial profiling of human COVID-19 brains reveals neuroinflammation with distinct microanatomical microglia-T-cell interactions

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Enhanced C/EBP binding to G·T mismatches facilitates fixation of CpG mutations in cancer and adult stem cells

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High-fat diet-activated fatty acid oxidation mediates intestinal stemness and tumorigenicity

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BPS Publications

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Metabolic regulator IAPP (Amylin) is required for BRAF and RAS oncogene-induced senescence

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BMI1 Inhibition Eliminates Residual Cancer Stem Cells after PD1 Blockade and Activates Antitumor Immunity to Prevent Metastasis and Relapse

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Disrupting Mitochondrial Copper Distribution Inhibits Leukemic Stem Cell Self-Renewal

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H3 K27M and EZHIP Impede H3K27-Methylation Spreading by Inhibiting Allosterically Stimulated PRC2

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Inhibition of Glutamine Utilization Synergizes with Immune Checkpoint Inhibitor to Promote Antitumor Immunity

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Tandem Deubiquitination and Acetylation of SPRTN Promotes DNA-Protein Crosslink Repair and Protects against Aging

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Ectosomal PKM2 Promotes HCC by Inducing Macrophage Differentiation and Remodeling the Tumor Microenvironment

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Glutamine Metabolism Controls Chondrocyte Identity and Function

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A Cell-Autonomous Signature of Dysregulated Protein Phosphorylation Underlies Muscle Insulin Resistance in Type 2 Diabetes

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YTHDF3 Induces the Translation of m6A-Enriched Gene Transcripts to Promote Breast Cancer Brain Metastasis

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Developmental partitioning of SYK and ZAP70 prevents autoimmunity and cancer

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SETD2 Restricts Prostate Cancer Metastasis by Integrating EZH2 and AMPK Signaling Pathways

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UTX promotes CD8+ T cell-mediated antiviral defenses but reduces T cell durability

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Golgi apparatus-synthesized sulfated glycosaminoglycans mediate polymerization and activation of the cGAMP sensor STING

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Reducing acetylated tau is neuroprotective in brain injury

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Paternal obesity impairs hepatic gluconeogenesis of offspring by altering Igf2/H19 DNA methylation

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mTORC1 stimulates cell growth through SAM synthesis and m6A mRNA-dependent control of protein synthesis

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IRF1 governs the differential interferon-stimulated gene responses in human monocytes and macrophages by regulating chromatin accessibility

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Centromeric chromatin integrity is compromised by loss of Cdk5rap2, a transcriptional activator of CENP-A

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  histone H3
  
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BPS Publications

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Acetyl-CoA Synthetase 2: A Critical Linkage in Obesity-Induced Tumorigenesis in Myeloma

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Ad and AAV8-Mediated ABCA1 Gene Therapy in a Murine Model with Retinal Ischemia/Reperfusion Injuries

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cell.com/molecular-therapy-family/methods/abstract/S2329-0501(21)00012-7
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NF-κB/Cartilage Acidic Protein 1 Promotes Ultraviolet B Irradiation-Induced Apoptosis of Human Lens Epithelial Cells

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Cancer-associated exportin-6 upregulation inhibits the transcriptionally repressive and anticancer effects of nuclear profilin-1

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RAD52 Adjusts Repair of Single-Strand Breaks via Reducing DNA-Damage-Promoted XRCC1/LIG3α Co-localization

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Nuclear cGAS Functions Non-canonically to Enhance Antiviral Immunity via Recruiting Methyltransferase Prmt5

1
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  Rabbit monoclonal anti-H3
  
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The palmitoyl acyltransferase ZDHHC14 controls Kv1-family potassium channel clustering at the axon initial segment

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Coupled Control of Distal Axon Integrity and Somal Responses to Axonal Damage by the Palmitoyl Acyltransferase ZDHHC17

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ARID1A Mutations Promote P300-Dependent Endometrial Invasion through Super-Enhancer Hyperacetylation

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Metabolic Reprogramming Induces Germinal Center B Cell Differentiation through Bcl6 Locus Remodeling

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Critical Role for Cold Shock Protein YB-1 in Cytokinesis

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Synapse type-specific proteomic dissection identifies IgSF8 as a hippocampal CA3 microcircuit organizer

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TDP-43 Triggers Mitochondrial DNA Release via mPTP to Activate cGAS/STING in ALS

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The Lipid Handling Capacity of Subcutaneous Fat Is Programmed by mTORC2 during Development

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Phosphorylation of T107 by CamKIIδ Regulates the Detoxification Efficiency and Proteomic Integrity of Glyoxalase 1

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Pharmacological enhancement of TFEB-mediated autophagy alleviated neuronal death in oxidative stress-induced Parkinson’s disease models

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Recycling endosomes in mature epithelia restrain tumorigenic signaling

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  DOI: 10.1158/0008-5472.CAN-18-4075
  
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Phospho-Ser784-VCP Is Required for DNA Damage Response and Is Associated with Poor Prognosis of Chemotherapy-Treated Breast Cancer

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PARP1 inhibitors trigger innate immunity via PARP1 trapping-induced DNA damage response

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  DOI: 10.7554/eLife.60637
  
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BPS Publications

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  DOI: 10.1111/bph.15182
  
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Proteome Instability Is a Therapeutic Vulnerability in Mismatch Repair-Deficient Cancer

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Partial loss of CFIm25 causes learning deficits and aberrant neuronal alternative polyadenylation

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A novel compound DBZ ameliorates neuroinflammation in LPS-stimulated microglia and ischemic stroke rats: Role of Akt(Ser473)/GSK3β(Ser9)-mediated Nrf2 activation

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Neurofibromin Is an Estrogen Receptor-α Transcriptional Co-repressor in Breast Cancer

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GLI transcriptional repression regulates tissue-specific enhancer activity in response to Hedgehog signaling

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Long noncoding RNA SOX2OT promotes the proliferation of pancreatic cancer by binding to FUS

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NF-κB/Cartilage Acidic Protein 1 Promotes Ultraviolet B Irradiation-Induced Apoptosis of Human Lens Epithelial Cells | DNA and Cell Biology

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Dual Regulation of Histone Methylation by mTOR Complexes Controls Glioblastoma Tumor Cell Growth via EZH2 and SAM

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BPS Publications

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  anti‐rabbit Histone H3
  
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Phosphorylation of Npas4 by MAPK Regulates Reward-Related Gene Expression and Behaviors

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Genetic Heterogeneity of BRAF Fusion Kinases in Melanoma Affects Drug Responses

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HDAC3 inhibition prevents blood-brain barrier permeability through Nrf2 activation in type 2 diabetes male mice

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Non-canonical mTORC2 Signaling Regulates Brown Adipocyte Lipid Catabolism through SIRT6-FoxO1

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Decreased levels of constitutive proteasomes in experimental autoimmune encephalomyelitis may be caused by a combination of subunit displacement and reduced Nfe2l1 expression

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BPS Publications

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  DOI: 10.1111/bph.14754
  
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Inadequate DNA Damage Repair Promotes Mammary Transdifferentiation, Leading to BRCA1 Breast Cancer

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Distinct Hepatic PKA and CDK Signaling Pathways Control Activity-Independent Pyruvate Kinase Phosphorylation and Hepatic Glucose Production

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LEFKOTHEA Regulates Nuclear and Chloroplast mRNA Splicing in Plants

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TREM-1 Protects HIV-1-Infected Macrophages from Apoptosis through Maintenance of Mitochondrial Function

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The Toll Signaling Pathway Targets the Insulin-like Peptide Dilp6 to Inhibit Growth in Drosophila

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Divergent Polypharmacology-Driven Cellular Activity of Structurally Similar Multi-Kinase Inhibitors through Cumulative Effects on Individual Targets

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Therapeutic Ligands Antagonize Estrogen Receptor Function by Impairing Its Mobility

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Pharmacological Activation of Pyruvate Kinase M2 Inhibits CD4+ T Cell Pathogenicity and Suppresses Autoimmunity

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CDK8 Regulates Insulin Secretion and Mediates Postnatal and Stress-Induced Expression of Neuropeptides in Pancreatic β Cells

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Chemical chaperone treatment improves levels and distributions of connexins in Cx50D47A mouse lenses

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Neuronally Enriched RUFY3 Is Required for Caspase-Mediated Axon Degeneration

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Untitled document

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Untitled document

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Untitled document

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Ribosomal Proteins Regulate MHC Class I Peptide Generation for Immunosurveillance

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An Endothelial-to-Adipocyte Extracellular Vesicle Axis Governed by Metabolic State

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NONO Detects the Nuclear HIV Capsid to Promote cGAS-Mediated Innate Immune Activation

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Non-canonical Activation of the DNA Sensing Adaptor STING by ATM and IFI16 Mediates NF-κB Signaling after Nuclear DNA Damage

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PKR Senses Nuclear and Mitochondrial Signals by Interacting with Endogenous Double-Stranded RNAs

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SIRT1 Activation Disrupts Maintenance of Myelodysplastic Syndrome Stem and Progenitor Cells by Restoring TET2 Function

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FANCA Promotes DNA Double-Strand Break Repair by Catalyzing Single-Strand Annealing and Strand Exchange

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Inhibition of Methyltransferase Setd7 Allows the In Vitro Expansion of Myogenic Stem Cells with Improved Therapeutic Potential

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Chemical chaperone treatment improves levels and distributions of connexins in Cx50D47A mouse lenses

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Targeting the Senescence-Overriding Cooperative Activity of Structurally Unrelated H3K9 Demethylases in Melanoma

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Helicobacter pylori Infection Modulates Host Cell Metabolism through VacA-Dependent Inhibition of mTORC1

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Reshaping of the Dendritic Cell Chromatin Landscape and Interferon Pathways during HIV Infection

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lncRNA Functional Networks in Oligodendrocytes Reveal Stage-Specific Myelination Control by an lncOL1/Suz12 Complex in the CNS

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Mutant p53 Gains Its Function via c-Myc Activation upon CDK4 Phosphorylation at Serine 249 and Consequent PIN1 Binding

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Simultaneous Multiplexed Imaging of mRNA and Proteins with Subcellular Resolution in Breast Cancer Tissue Samples by Mass Cytometry

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A Chemical Proteomics Approach to Reveal Direct Protein-Protein Interactions in Living Cells

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Rapid DNA replication origin licensing protects stem cell pluripotency

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Epigenetic Therapy Ties MYC Depletion to Reversing Immune Evasion and Treating Lung Cancer

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Nov 2017
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Aberrant TGF-β Signaling Drives Castration-Resistant Prostate Cancer in a Male Mouse Model of Prostate Tumorigenesis

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m6A Demethylase ALKBH5 Maintains Tumorigenicity of Glioblastoma Stem-like Cells by Sustaining FOXM1 Expression and Cell Proliferation Program

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