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    6-O-angeloylplenolin inhibits osteoclastogenesis in vitro via suppressing c-Src/NF-κB/NFATc1 pathways and ameliorates bone resorption in collagen-induced arthritis mouse model
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    AXL/WRNIP1 mediates replication stress response and promotes therapy resistance and metachronous metastasis in HER2+ breast cancer
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    EZH2 as a major histone methyltransferase in PDGF-BB-activated orbital fibroblast in the pathogenesis of Graves’ ophthalmopathy
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    Class I HDAC inhibitors enhance antitumor efficacy and persistence of CAR-T cells by activation of the Wnt pathway
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    MARCH2, a novel oncogene-regulated SNAIL E3 ligase, suppresses triple negative breast cancer metastases
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    Histone lysine demethylase 4 family proteins maintain the transcriptional program and adrenergic cellular state of MYCN-amplified neuroblastoma
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    Lupenone improves motor dysfunction in spinal cord injury mice through inhibiting the inflammasome activation and pyroptosis in microglia via the nuclear factor kappa B pathway
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    Paradoxical imbalance between activated lymphocyte protein synthesis capacity and rapid division rate
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    Hepatic malonyl-CoA synthesis restrains gluconeogenesis by suppressing fat oxidation, pyruvate carboxylation, and amino acid availability
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    Homozygous ALS-linked mutations in TARDBP/TDP-43 lead to hypoactivity and synaptic abnormalities in human iPSC-derived motor neurons
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    The GATOR2 complex maintains lysosomal-autophagic function by inhibiting the protein degradation of MiT/TFEs
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    Targeting EMSY-mediated methionine metabolism is a potential therapeutic strategy for triple-negative breast cancer
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    Augmentation of scleral glycolysis promotes myopia through histone lactylation
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    circGlis3 promotes β-cell dysfunction by inhibiting hnRNPF nuclear translocation and encoding Glis3-348aa protein
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    Cleavage of the pseudoprotease iRhom2 by the signal peptidase complex reveals an ER-to-nucleus signaling pathway
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    Metabolic switch regulates lineage plasticity and induces synthetic lethality in triple-negative breast cancer
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    Profiling nuclear cysteine ligandability and effects on nuclear localization using proximity labeling-coupled chemoproteomics
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  31. Oct 2023
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    Tyrosine catabolism enhances genotoxic chemotherapy by suppressing translesion DNA synthesis in epithelial ovarian cancer
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    Crucial roles of the BRCA1-BARD1 E3 ubiquitin ligase activity in homology-directed DNA repair
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    Targeting LYPLAL1-mediated cGAS depalmitoylation enhances the response to anti-tumor immunotherapy
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    mTORC1 stimulates cell growth through SAM synthesis and m6A mRNA-dependent control of protein synthesis
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  37. Sep 2023
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    Discordant interactions between YAP1 and polycomb group protein SCML2 determine cell fate
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    Highly multiplexed spatial analysis identifies tissue-resident memory T cells as drivers of ulcerative and immune checkpoint inhibitor induced colitis
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    Paternal obesity impairs hepatic gluconeogenesis of offspring by altering Igf2/H19 DNA methylation
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    LSR targets YAP to modulate intestinal Paneth cell differentiation
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    Activation of AKT induces EZH2-mediated β-catenin trimethylation in colorectal cancer
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  43. Aug 2023
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    The two enantiomers of 2-hydroxyglutarate differentially regulate cytotoxic T cell function
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    NFYC-37 promotes tumor growth by activating the mevalonate pathway in bladder cancer
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  46. Jul 2023
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    Ketolysis drives CD8+ T cell effector function through effects on histone acetylation
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    Integrin β3 Promotes Resistance to EGFR-TKI in Non-Small-Cell Lung Cancer by Upregulating AXL through the YAP Pathway
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    Methionine oxidation activates pyruvate kinase M2 to promote pancreatic cancer metastasis
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    Protein interactome and cell-type expression analyses reveal that cytoplasmic FMR1-interacting protein 1 (CYFIP1), but not CYFIP2, associates with astrocytic focal adhesion
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  121. May 2022
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    Fumarate inhibits PTEN to promote tumorigenesis and therapeutic resistance of type2 papillary renal cell carcinoma
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    Lactic acid promotes PD-1 expression in regulatory T cells in highly glycolytic tumor microenvironments
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    Acetyl-CoA Synthetase 2: A Critical Linkage in Obesity-Induced Tumorigenesis in Myeloma
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    Nuclear cGAS Functions Non-canonically to Enhance Antiviral Immunity via Recruiting Methyltransferase Prmt5
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      Rabbit monoclonal anti-H3

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    Phosphorylation of T107 by CamKIIδ Regulates the Detoxification Efficiency and Proteomic Integrity of Glyoxalase 1
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  235. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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      RRID:AB_10544537

      DOI: 10.1111/bph.15182

      Resource: (Cell Signaling Technology Cat# 4499, RRID:AB_10544537)

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15182
  236. www.sciencedirect.com www.sciencedirect.com
    Proteome Instability Is a Therapeutic Vulnerability in Mismatch Repair-Deficient Cancer
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      RRID:AB_10544537

      DOI: 10.1016/j.ccell.2020.01.011

      Resource: (Cell Signaling Technology Cat# 4499, RRID:AB_10544537)

      Curator: @ethanbadger

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    sciencedirect.com/science/article/pii/S1535610820300507
  237. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Partial loss of CFIm25 causes learning deficits and aberrant neuronal alternative polyadenylation
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    1. scibot 11 Sep 2020
      RRID:AB_10544537

      DOI: 10.7554/eLife.50895

      Resource: (Cell Signaling Technology Cat# 4499, RRID:AB_10544537)

      Curator: @evieth

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    ncbi.nlm.nih.gov/pmc/articles/PMC7176433/
  238. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A novel compound DBZ ameliorates neuroinflammation in LPS-stimulated microglia and ischemic stroke rats: Role of Akt(Ser473)/GSK3β(Ser9)-mediated Nrf2 activation
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    1. scibot 11 Sep 2020
      RRID:AB_10544537

      DOI: 10.1016/j.redox.2020.101644

      Resource: (Cell Signaling Technology Cat# 4499, RRID:AB_10544537)

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    ncbi.nlm.nih.gov/pmc/articles/PMC7371982/