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Aug 2025
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Extrachromosomal DNA biogenesis is dependent on DNA looping and religation by YY1-Lig3-PARylation complex

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  DOI: 10.1016/j.molcel.2025.07.007
  
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ASH2L-K312-Lac Stimulates Angiogenesis in Tumors to Expedite the Malignant Progression of Hepatocellular Carcinoma

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1. scibot 05 Aug 2025
  
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  DOI: 10.1002/advs.202509477
  
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advanced.onlinelibrary.wiley.com/doi/full/10.1002/advs.202509477
Jul 2025
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RACK7 senses and fine-tunes enhancer activity

1
1. scibot 31 Jul 2025
  
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  DOI: 10.1016/j.isci.2025.113083
  
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1-s2.0-S2589004225014555-main-html.html

1
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52.53.155.43/644b847ccbd9fd7a361f652a83914faf17916b63/1-s2.0-S2589004225014555-main-html.html
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Epigenome profiling identifies H3K27me3 regulation of extracellular matrix composition in human corticogenesis

1
1. scibot 23 Jul 2025
  
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  DOI: 10.1016/j.neuron.2025.06.016
  
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sciencedirect.com/science/article/pii/S089662732500474X
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CRISPR-based screening identifies the role of KRAB-containing transcription factors ZIM3 and ZNF394 in human major zygotic genome activation

1
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  DOI: 10.1016/j.celrep.2025.116015
  
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cell.com/cell-reports/fulltext/S2211-1247(25)00786-7
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Combining EHMT and PARP Inhibition: A Strategy to Diminish Therapy-Resistant Ovarian Cancer Tumor Growth while Stimulating Immune Activation

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pmc.ncbi.nlm.nih.gov/articles/PMC11543919/
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1-s2.0-S2589004225013446-main-html.html

1
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52.53.155.43/3a940a222b37943f01bb89b56d8fe0b40f820eb6/1-s2.0-S2589004225013446-main-html.html
Jun 2025
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Non-canonical PRC1.1 licenses transcriptional response to enable Treg plasticity in immune adaptation

1
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52.53.155.43/39661a60067369c81e4f8c30deffb29c14ec6c80/PDF-html.html
May 2025
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Chromatin modification abnormalities by CHD7 and KMT2C loss promote medulloblastoma progression

1
1. scibot 20 May 2025
  
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  DOI: 10.1016/j.celrep.2025.115673
  
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sciencedirect.com/science/article/pii/S2211124725004449
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Isocitrate dehydrogenase 1 primes group-3 medulloblastomas for cuproptosis

1
1. scibot 17 May 2025
  
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  DOI: 10.1016/j.ccell.2025.04.013
  
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sciencedirect.com/science/article/pii/S1535610825001722
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KMT2C deficiency drives transdifferentiation of double-negative prostate cancer and confer resistance to AR-targeted therapy

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1. scibot 16 May 2025
  
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  DOI: 10.1016/j.ccell.2025.04.002
  
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sciencedirect.com/science/article/pii/S1535610825001394
Apr 2025
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DUX-mediated configuration of p300/CBP drives minor zygotic genome activation independent of its catalytic activity

1
1. scibot 09 Apr 2025
  
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  DOI: 10.1016/j.celrep.2025.115544
  
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sciencedirect.com/science/article/pii/S2211124725003158
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BCG-trained macrophages couple LDLR upregulation to type I IFN responses and antiviral immunity

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1. scibot 03 Apr 2025
  
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  DOI: 10.1016/j.celrep.2025.115493
  
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sciencedirect.com/science/article/pii/S2211124725002645
Mar 2025
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Conservation of dichromatin organization along regional centromeres

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1. scibot 29 Mar 2025
  
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  DOI: 10.1016/j.xgen.2025.100819
  
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sciencedirect.com/science/article/pii/S2666979X25000758
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Antagonistic roles for MITF and TFE3 in melanoma plasticity

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1. scibot 29 Mar 2025
  
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  DOI: 10.1016/j.celrep.2025.115474
  
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sciencedirect.com/science/article/pii/S2211124725002451
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Lipoylation inhibition enhances radiation control of lung cancer by suppressing homologous recombination DNA damage repair

1
1. scibot 14 Mar 2025
  
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  DOI: 10.1126/sciadv.adt1241
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11900879/
Feb 2025
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Nuclear-localized HKDC1 promotes hepatocellular carcinoma through phosphorylating RBBP5 to upregulate H3K4me3

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1. scibot 04 Feb 2025
  
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sciencedirect.com/science/article/pii/S221112472500021X
Jan 2025
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Deciphering transcription activity of mammalian early embryos unveils on/off of zygotic genome activation by protein translation/degradation

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1. scibot 17 Jan 2025
  
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  DOI: 10.1016/j.celrep.2024.115215
  
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Nucleosomal asymmetry shapes histone mark binding and promotes poising at bivalent domains

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  DOI: 10.1016/j.molcel.2024.12.002
  
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sciencedirect.com/science/article/pii/S1097276524009973
Dec 2024
52.53.155.43 52.53.155.43

can-24-1611-html.html

3
1. scibot 19 Dec 2024
  
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  DOI: 10.1158/0008-5472.can-24-1611
  
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52.53.155.43/75f09a51d2e08f557660a3e31ff8f3f3198b5c01/can-24-1611-html.html
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H4K20me3-Mediated Repression of Inflammatory Genes is a Characteristic and Targetable Vulnerability of Persister Cancer Cells

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1. scibot 13 Dec 2024
  
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  DOI: 10.1158/0008-5472.CAN-24-0529
  
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pmc.ncbi.nlm.nih.gov/articles/PMC7617193/
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Epigenetic and Oncogenic Inhibitors Cooperatively Drive Differentiation and Kill KRAS-Mutant Colorectal Cancers

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1. scibot 11 Dec 2024
  
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  DOI: 10.1158/2159-8290.CD-23-0866
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11609823/
Nov 2024
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ACSS2 acts as a lactyl-CoA synthetase and couples KAT2A to function as a lactyltransferase for histone lactylation and tumor immune evasion

1
1. scibot 24 Nov 2024
  
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  DOI: 10.1016/j.cmet.2024.10.015
  
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can-24-0529-html.html

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Sep 2024
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Developmental Cytoplasmic-to-Nuclear Translocation of RNA-Binding Protein HuR Is Required for Adult Neurogenesis

1
1. scibot 25 Sep 2024
  
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  DOI: 10.1016/j.celrep.2019.10.127
  
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sciencedirect.com/science/article/pii/S2211124719314603
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Promoter DNA methylation and transcription factor condensation are linked to transcriptional memory in mammalian cells

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  DOI: 10.1016/j.cels.2024.08.007
  
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Aug 2024
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Characterizing Relationships between T-cell Inflammation and Outcomes in Patients with High-Risk Neuroblastoma According to Mesenchymal and Adrenergic Signatures

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1. scibot 30 Aug 2024
  
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  DOI: 10.1158/2767-9764.CRC-24-0214
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11350481/
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ADAM interact with large protein complexes to regulate Histone modification, gene expression and splicing

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1. scibot 23 Aug 2024
  
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  DOI: 10.1101/2024.08.18.608474
  
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biorxiv.org/content/10.1101/2024.08.18.608474v1
Jun 2024
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KDM5-mediated transcriptional activation of ribosomal protein genes alters translation efficiency to regulate mitochondrial metabolism in neurons

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1. scibot 30 Jun 2024
  
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  DOI: 10.1093/nar/gkae261
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11194071/
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Lineage specification in glioblastoma is regulated by METTL7B

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  DOI: 10.1016/j.celrep.2024.114309
  
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sciencedirect.com/science/article/pii/S2211124724006375
May 2024
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Deletion of the mRNA endonuclease Regnase-1 promotes NK cell anti-tumor activity via OCT2-dependent transcription of Ifng

2
1. scibot 31 May 2024
  
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  DOI: 10.1016/j.immuni.2024.05.006
  
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  DOI: 10.1016/j.immuni.2024.05.006
  
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Epigenetic activation of SOX11 is associated with recurrence and progression of ductal carcinoma in situ to invasive breast cancer

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Cis-regulatory control of transcriptional timing and noise in response to estrogen

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Squalene-epoxidase-catalyzed 24(S),25-epoxycholesterol synthesis promotes trained-immunity-mediated antitumor activity

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Nuclear RNA homeostasis promotes systems-level coordination of cell fate and senescence

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SP6 controls human cytotrophoblast fate decisions and trophoblast stem cell establishment by targeting MSX2 regulatory elements

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Iterative oxidation by TET1 is required for reprogramming of imprinting control regions and patterning of mouse sperm hypomethylated regions

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Transcription elongation defects link oncogenic SF3B1 mutations to targetable alterations in chromatin landscape

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Enhancer-promoter activation by the Kaposi sarcoma-associated herpesvirus episome maintenance protein LANA

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The iron chelator and OXPHOS inhibitor VLX600 induces mitophagy and an autophagy-dependent type of cell death in glioblastoma cells

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The iron chelator and OXPHOS inhibitor VLX600 induces mitophagy and an autophagy-dependent type of cell death in glioblastoma cells

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Mapping chromatin state and transcriptional response in CIC-DUX4 undifferentiated round cell sarcoma

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Targeting EMSY-mediated methionine metabolism is a potential therapeutic strategy for triple-negative breast cancer

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PRDM3/16 Regulate Chromatin Accessibility Required for NKX2-1 Mediated Alveolar Epithelial Differentiation and Function

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IL-15-dependent immune crosstalk between natural killer cells and dendritic cells in HIV-1 elite controllers

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Bisphenol S induces brown adipose tissue whitening and aggravates diet-induced obesity in an estrogen-dependent manner

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Mof plays distinct roles in hepatic lipid metabolism under healthy or non-alcoholic fatty liver conditions

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Cooperation of MLL1 and Jun in controlling H3K4me3 on enhancers in colorectal cancer

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I-CBP112 declines overexpression of ATP-binding cassette transporters and sensitized drug-resistant MDA-MB-231 and A549 cell lines to chemotherapy drugs

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Release of Histone H3K4-reading transcription factors from chromosomes in mitosis is independent of adjacent H3 phosphorylation

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mTORC1 stimulates cell growth through SAM synthesis and m6A mRNA-dependent control of protein synthesis

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Ethanol changes Nestin-promoter induced neural stem cells to disturb newborn dendritic spine remodeling in the hippocampus of mice

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Multi-omics comparison of malignant and normal uveal melanocytes reveals molecular features of uveal melanoma

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Activation of AKT induces EZH2-mediated β-catenin trimethylation in colorectal cancer

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The SMC5/6 complex compacts and silences unintegrated HIV-1 DNA and is antagonized by Vpr

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Spermine is a natural suppressor of AR signaling in castration-resistant prostate cancer

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An EZH2-NF-κB Regulatory Axis Drives Expression of Pro-Oncogenic Gene Signatures in Triple Negative Breast Cancer

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METTL14 regulates chromatin bivalent domains in mouse embryonic stem cells

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(R)-2-hydroxyglutarate inhibits KDM5 histone lysine demethylases to drive transformation in IDH-mutant cancers

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Complex regulation of Eomes levels mediated through distinct functional features of the Meteor long non-coding RNA locus

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Methionine restriction promotes cGAS activation and chromatin untethering through demethylation to enhance antitumor immunity

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Depletion of CUL4B in macrophages ameliorates diabetic kidney disease via miR-194-5p/ITGA9 axis

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Exercise improves homeostasis of the intestinal epithelium by activation of APJ-AMPK signaling

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RUNX1 colludes with NOTCH1 to reprogram chromatin in T cell acute lymphoblastic leukemia

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The Journal of Physiology - 2023 - Chae - Exercise improves homeostasis of the intestinal epithelium by activation of-html.html

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The glycolysis/HIF-1α axis defines the inflammatory role of IL-4-primed macrophages

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Bcl-xL is translocated to the nucleus via CtBP2 to epigenetically promote metastasis

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Release of Histone H3K4-reading transcription factors from chromosomes in mitosis is independent of adjacent H3 phosphorylation

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TET1 Catalytic Activity is Required for Reprogramming of Imprinting Control Regions and Patterning of Sperm-Specific Hypomethylated Regions

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Arginine shortage induces replication stress and confers genotoxic resistance by inhibiting histone H4 translation and promoting PCNA ubiquitination

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Histone malonylation is regulated by SIRT5 and KAT2A

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Mutant NPM1 Hijacks Transcriptional Hubs to Maintain Pathogenic Gene Programs in Acute Myeloid Leukemia

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Combinatory EHMT and PARP inhibition induces an interferon response and a CD8 T cell-dependent tumor regression in PARP inhibitor-resistant models

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Decreased expression of EZH2 in granulosa cells contributes to endometriosis-associated infertility by targeting IL-1R2

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Essential role of MESP1-RING1A complex in cardiac differentiation

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Argininosuccinate lyase drives activation of mutant TERT promoter in glioblastomas

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Single-cell sequencing reveals activation of core transcription factors in PRC2-deficient malignant peripheral nerve sheath tumor

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Structural basis for product specificities of MLL family methyltransferases

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Targeting histone methylation to reprogram the transcriptional state that drives survival of drug-tolerant myeloid leukemia persisters

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DPY30 acts as an ASH2L-specific stabilizer to stimulate the enzyme activity of MLL family methyltransferases on different substrates

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Chromatin-bound RB targets promoters, enhancers, and CTCF-bound loci and is redistributed by cell-cycle progression

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Reciprocal SOX2 regulation by SMAD1-SMAD3 is critical for anoikis resistance and metastasis in cancer

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RPA1 controls chromatin architecture and maintains lipid metabolic homeostasis

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Clioquinol as an inhibitor of JmjC-histone demethylase exhibits common and unique histone methylome and transcriptome between clioquinol and hypoxia

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Single-cell epigenetic analysis reveals principles of chromatin states in H3.3-K27M gliomas

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XIST loss impairs mammary stem cell differentiation and increases tumorigenicity through Mediator hyperactivation

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H3-K27M-mutant nucleosomes interact with MLL1 to shape the glioma epigenetic landscape

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Linkage of methionine addiction, histone lysine hypermethylation, and malignancy

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PTIP governs NAD+ metabolism by regulating CD38 expression to drive macrophage inflammation

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Dynamic control of chromatin-associated m6A methylation regulates nascent RNA synthesis

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The KRAS-G12D mutation induces Metabolic Vulnerability in B-cell Acute Lymphoblastic Leukemia

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An Inducible CRISPR/Cas9 Screen Identifies DTX2 as a Transcriptional Regulator of Human Telomerase

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Cellular plasticity upon proton irradiation determines tumor cell radiosensitivity

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Genome-wide identification of the genetic basis of amyotrophic lateral sclerosis

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TRACE generates fluorescent human reporter cell lines to characterize epigenetic pathways

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Low folate induces abnormal neuronal maturation and DNA hypomethylation of neuronal differentiation-related genes in cultured mouse neural stem and progenitor cells

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Untitled document

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Untitled document

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Untitled document

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Whole-genome sequencing of H3K4me3 and DNA methylation in human sperm reveals regions of overlap linked to fertility and development

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ChIP-seq protocol for sperm cells and embryos to assess environmental impacts and epigenetic inheritance

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Metabolic regulator IAPP (Amylin) is required for BRAF and RAS oncogene-induced senescence

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Histone H3 lysine 4 trimethylation in sperm is transmitted to the embryo and associated with diet-induced phenotypes in the offspring

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Decoding dynamic epigenetic landscapes in human oocytes using single-cell multi-omics sequencing

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Human placental cytotrophoblast epigenome dynamics over gestation and alterations in placental disease

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Cholesterol Pathway Inhibition Induces TGF-β Signaling to Promote Basal Differentiation in Pancreatic Cancer

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Integrated Metabolic and Epigenomic Reprograming by H3K27M Mutations in Diffuse Intrinsic Pontine Gliomas

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The bone microenvironment increases phenotypic plasticity of ER+ breast cancer cells

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Complex-dependent histone acetyltransferase activity of KAT8 determines its role in transcription and cellular homeostasis

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SETD2 Restricts Prostate Cancer Metastasis by Integrating EZH2 and AMPK Signaling Pathways

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The SMC5/6 complex compacts and silences unintegrated HIV-1 DNA and is antagonized by Vpr

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mTORC1 stimulates cell growth through SAM synthesis and m6A mRNA-dependent control of protein synthesis

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linc-AAM Facilitates Gene Expression Contributing to Macrophage Activation and Adaptive Immune Responses

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ARID1A Mutations Promote P300-Dependent Endometrial Invasion through Super-Enhancer Hyperacetylation

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Microbiota-Induced Type I Interferons Instruct a Poised Basal State of Dendritic Cells

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Cdk1 Controls Global Epigenetic Landscape in Embryonic Stem Cells

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One-Carbon Metabolism Supports S-Adenosylmethionine and Histone Methylation to Drive Inflammatory Macrophages

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Small-molecule targeting of oncogenic FTO demethylase in acute myeloid leukemia

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A Functional Link between Nuclear RNA Decay and Transcriptional Control Mediated by the Polycomb Repressive Complex 2

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JARID1B expression and its function in DNA damage repair are tightly regulated by miRNAs in breast cancer

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A CHAF1B-Dependent Molecular Switch in Hematopoiesis and Leukemia Pathogenesis

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Epigenetic Restoration of Fetal-like IGF1 Signaling Inhibits Leukemia Stem Cell Activity

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Examining the Roles of H3K4 Methylation States with Systematically Characterized Antibodies

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Mutant NPM1 Maintains the Leukemic State through HOX Expression

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Cooperative Enhancer Activation by TLX1 and STAT5 Drives Development of NUP214-ABL1/TLX1-Positive T Cell Acute Lymphoblastic Leukemia

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Inhibition of Methyltransferase Setd7 Allows the In Vitro Expansion of Myogenic Stem Cells with Improved Therapeutic Potential

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Targeting the Senescence-Overriding Cooperative Activity of Structurally Unrelated H3K9 Demethylases in Melanoma

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Drosophila PAF1 Modulates PIWI/piRNA Silencing Capacity

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sciencedirect.com/science/article/pii/S0960982217309569
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Type 2 Diabetes Variants Disrupt Function of SLC16A11 through Two Distinct Mechanisms

1
1. scibot 08 Nov 2017
  
  in Public
  
  AB_2616028
  
  Curator: @chewbeccax
  
  Resource used:
  
  (Cell Signaling Technology Cat# 9751, RRID:AB_2616028)
  
  SciCrunch record: RRID:AB_2616028
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:AB_2616028 RRIDCUR:Validated
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scibot

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sciencedirect.com/science/article/pii/S0092867417306943

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