387 Matching Annotations
  1. Jan 2022
  2. journals.plos.org journals.plos.org
    Species-specific quantification of circulating ebolavirus burden using VP40-derived peptide variants
    1
    1. scibot 03 Jan 2022
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      DOI: 10.1371/journal.ppat.1010039

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    journals.plos.org/plospathogens/article
  3. Dec 2021
  4. www.sciencedirect.com www.sciencedirect.com
    Assessing kinetics and recruitment of DNA repair factors using high content screens
    1
    1. scibot 29 Dec 2021
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      DOI: 10.1016/j.celrep.2021.110176

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    sciencedirect.com/science/article/pii/S2211124721016764
  5. www.sciencedirect.com www.sciencedirect.com
    Substratum stiffness regulates Erk signaling dynamics through receptor-level control
    1
    1. scibot 29 Dec 2021
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      DOI: 10.1016/j.celrep.2021.110181

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    sciencedirect.com/science/article/pii/S2211124721016818
  6. link.springer.com link.springer.com
    Leukemia inhibitory factor modulates the peripheral immune response in a rat model of emergent large vessel occlusion
    1
    1. scibot 22 Dec 2021
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      DOI: 10.1186/s12974-018-1326-y

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    link.springer.com/article/10.1186/s12974-018-1326-y
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    EGFR transactivates RON to drive oncogenic crosstalk
    1
    1. scibot 11 Dec 2021
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      DOI: 10.7554/eLife.63678

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    ncbi.nlm.nih.gov/pmc/articles/PMC8654365/
  8. www.sciencedirect.com www.sciencedirect.com
    Calpain-2 regulates hypoxia/HIF-induced plasticity toward amoeboid cancer cell migration and metastasis
    1
    1. scibot 09 Dec 2021
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      DOI: 10.1016/j.cub.2021.11.040

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    sciencedirect.com/science/article/pii/S0960982221015992
  9. journals.physiology.org journals.physiology.org
    Anemic Hypoxemia Reduces Myoblast Proliferation and Muscle Growth in Late Gestation Fetal Sheep
    1
    1. scibot 08 Dec 2021
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      DOI: 10.1152/ajpregu.00342.2020

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    journals.physiology.org/doi/abs/10.1152/ajpregu.00342.2020
  10. Nov 2021
  11. 52.53.155.43 52.53.155.43
    ajpregu.00342.2020-html.html
    1
    1. scibot 24 Nov 2021
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      DOI: 10.1152/ajpregu.00342.2020

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    52.53.155.43/929b6923868831e320580be57c2774b268327ec6/ajpregu.00342.2020-html.html
  12. www.jneurosci.org www.jneurosci.org
    Frontotemporal Lobar Dementia Mutant Tau Impairs Axonal Transport through a Protein Phosphatase 1γ-Dependent Mechanism
    1
    1. scibot 13 Nov 2021
      RRID:AB_10956588

      DOI: 10.1523/JNEUROSCI.1914-20.2021

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    jneurosci.org/content/41/45/9431
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A role for SMARCB1 in synovial sarcomagenesis reveals that SS18-SSX induces canonical BAF destruction
    1
    1. scibot 09 Nov 2021
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      DOI: 10.1158/2159-8290.CD-20-1219

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    ncbi.nlm.nih.gov/pmc/articles/PMC8567602/
  14. www.sciencedirect.com www.sciencedirect.com
    DNAJB6b-enriched small extracellular vesicles decrease polyglutamine aggregation in in vitro and in vivo models of Huntington disease
    1
    1. scibot 09 Nov 2021
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      DOI: 10.1016/j.isci.2021.103282

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    sciencedirect.com/science/article/pii/S2589004221012517
  15. Oct 2021
  16. www.sciencedirect.com www.sciencedirect.com
    Reprogramming CBX8-PRC1 function with a positive allosteric modulator
    1
    1. scibot 29 Oct 2021
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      DOI: 10.1016/j.chembiol.2021.10.003

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    sciencedirect.com/science/article/pii/S2451945621004372
  17. www.sciencedirect.com www.sciencedirect.com
    Subtractive CRISPR screen identifies the ATG16L1/vacuolar ATPase axis as required for non-canonical LC3 lipidation
    1
    1. scibot 27 Oct 2021
      RRID:AB_10956588

      DOI: 10.1016/j.celrep.2021.109899

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    sciencedirect.com/science/article/pii/S2211124721013693
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation
    1
    1. scibot 15 Oct 2021
      RRID:AB_10956588

      DOI: 10.1371/journal.ppat.1009412

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    ncbi.nlm.nih.gov/pmc/articles/PMC8513853/
  19. www.sciencedirect.com www.sciencedirect.com
    Lentiviral-mediated ectopic expression of YAP and TAZ in YAPoff cancer cell lines
    1
    1. scibot 05 Oct 2021
      926-68070

      DOI: 10.1016/j.xpro.2021.100870

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    sciencedirect.com/science/article/pii/S2666166721005761
  20. www.sciencedirect.com www.sciencedirect.com
    RetroCHMP3 blocks budding of enveloped viruses without blocking cytokinesis
    1
    1. scibot 01 Oct 2021
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      DOI: 10.1016/j.cell.2021.09.008

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    sciencedirect.com/science/article/pii/S0092867421010552
  21. Sep 2021
  22. www.sciencedirect.com www.sciencedirect.com
    An additional NF-κB site allows HIV-1 subtype C to evade restriction by nuclear PYHIN proteins
    1
    1. scibot 22 Sep 2021
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      DOI: 10.1016/j.celrep.2021.109735

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    sciencedirect.com/science/article/pii/S2211124721011840
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An engineered transcriptional reporter of protein localization identifies regulators of mitochondrial and ER membrane protein trafficking in high-throughput CRISPRi screens
    1
    1. scibot 11 Sep 2021
      RRID:AB_10956588

      DOI: 10.7554/eLife.69142

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    ncbi.nlm.nih.gov/pmc/articles/PMC8423448/
  24. www.sciencedirect.com www.sciencedirect.com
    A strategy to assess the cellular activity of E3 ligase components against neo-substrates using electrophilic probes
    1
    1. scibot 09 Sep 2021
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      DOI: 10.1016/j.chembiol.2021.08.007

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    sciencedirect.com/science/article/pii/S2451945621003962
  25. Aug 2021
  26. www.sciencedirect.com www.sciencedirect.com
    Structured elements drive extensive circular RNA translation
    1
    1. scibot 26 Aug 2021
      RRID:AB_10956588

      DOI: 10.1016/j.molcel.2021.07.042

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    sciencedirect.com/science/article/pii/S1097276521006262
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ER – lysosome contacts at a pre-axonal region regulate axonal lysosome availability
    1
    1. scibot 17 Aug 2021
      RRID:AB_10956588

      DOI: 10.1038/s41467-021-24713-5

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    ncbi.nlm.nih.gov/pmc/articles/PMC8302662/
  28. www.sciencedirect.com www.sciencedirect.com
    TDP-43 condensation properties specify its RNA-binding and regulatory repertoire
    1
    1. scibot 15 Aug 2021
      RRID:AB_10956588

      DOI: 10.1016/j.cell.2021.07.018

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    sciencedirect.com/science/article/pii/S0092867421008771
  29. www.sciencedirect.com www.sciencedirect.com
    Severe deficiency of the voltage-gated sodium channel NaV1.2 elevates neuronal excitability in adult mice
    1
    1. scibot 15 Aug 2021
      RRID:AB_10956588

      DOI: 10.1016/j.celrep.2021.109495

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    sciencedirect.com/science/article/pii/S2211124721009220
  30. academic.oup.com academic.oup.com
    Endogenous piRNA-guided slicing triggers responder and trailer piRNA production from viral RNA in Aedes aegypti mosquitoes
    1
    1. scibot 15 Aug 2021
      RRID:AB_10956588

      DOI: 10.1093/nar/gkab640

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    academic.oup.com/nar/advance-article/doi/10.1093/nar/gkab640/6332816
  31. www.sciencedirect.com www.sciencedirect.com
    A photo-cross-linking GlcNAc analog enables covalent capture of N-linked glycoprotein-binding partners on the cell surface
    1
    1. scibot 15 Aug 2021
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      DOI: 10.1016/j.chembiol.2021.07.007

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    sciencedirect.com/science/article/pii/S2451945621003470
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Glycosylphosphatidylinositol biosynthesis and remodeling are required for neural tube closure, heart development, and cranial neural crest cell survival
    1
    1. scibot 14 Aug 2021
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      DOI: 10.7554/eLife.45248

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    ncbi.nlm.nih.gov/pmc/articles/PMC6611694/
  33. onlinelibrary.wiley.com onlinelibrary.wiley.com
    BAG3 is a negative regulator of ciliogenesis in glioblastoma and triple-negative breast cancer cells
    1
    1. scibot 12 Aug 2021
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      DOI: 10.1002/jcb.30073

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    onlinelibrary.wiley.com/doi/10.1002/jcb.30073
  34. www.sciencedirect.com www.sciencedirect.com
    Untitled document
    1
    1. scibot 10 Aug 2021
      RRID:AB_10956588

      DOI: 10.1016/j.molcel.2018.11.005

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    sciencedirect.com/science/article/pii/S109727651830947X
  35. www.sciencedirect.com www.sciencedirect.com
    Solenoid architecture of HUWE1 contributes to ligase activity and substrate recognition
    1
    1. scibot 07 Aug 2021
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      DOI: 10.1016/j.molcel.2021.06.032

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    sciencedirect.com/science/article/pii/S1097276521005438
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mechano-dependent signaling by Latrophilin/CIRL quenches cAMP in proprioceptive neurons
    1
    1. scibot 07 Aug 2021
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      DOI: 10.7554/eLife.28360

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    ncbi.nlm.nih.gov/pmc/articles/PMC5548486/
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    1. scibot 07 Aug 2021
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      DOI: 10.1016/j.molcel.2019.01.027

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    ncbi.nlm.nih.gov/pmc/articles/PMC6458999/
  38. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Ablation of neuronal ADAM17 impairs oligodendrocyte differentiation and myelination
    1
    1. scibot 07 Aug 2021
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      DOI: 10.1002/glia.23765

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    onlinelibrary.wiley.com/doi/10.1002/glia.23765
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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      DOI: 10.1016/j.celrep.2018.07.101

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    ncbi.nlm.nih.gov/pmc/articles/PMC6298213/
  40. f1000research.com f1000research.com
    Untitled document
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      DOI: 10.12688/f1000research.5337.1

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    f1000research.com/articles/3-230/v1
  41. Jul 2021
  42. elifesciences.org elifesciences.org
    USP49 potently stabilizes APOBEC3G protein by removing ubiquitin and inhibits HIV-1 replication
    1
    1. scibot 29 Jul 2021
      IRDye 680RD Goat anti-Mouse IgG (H + L), 0.5 mg Antibody

      DOI: 10.7554/eLife.48318

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    elifesciences.org/articles/48318
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    1. scibot 28 Jul 2021
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      DOI: 10.12688/f1000research.15166.2

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    ncbi.nlm.nih.gov/pmc/articles/PMC6240467/
  44. www.sciencedirect.com www.sciencedirect.com
    The Ebola Virus Nucleoprotein Recruits the Host PP2A-B56 Phosphatase to Activate Transcriptional Support Activity of VP30
    1
    1. scibot 27 Jul 2021
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      DOI: 10.1016/j.molcel.2017.11.034

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    sciencedirect.com/science/article/pii/S1097276517308936
  45. www.jneurosci.org www.jneurosci.org
    Diencephalic Size Is Restricted by a Novel Interplay Between GCN5 Acetyltransferase Activity and Retinoic Acid Signaling
    1
    1. scibot 27 Jul 2021
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      DOI: 10.1523/JNEUROSCI.2121-16.2017

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    jneurosci.org/content/37/10/2565
  46. www.sciencedirect.com www.sciencedirect.com
    Treprostinil reduces mitochondrial injury during rat renal ischemia-reperfusion injury
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    1. scibot 16 Jul 2021
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      DOI: 10.1016/j.biopha.2021.111912

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    Structure and dynamics of semaglutide- and taspoglutide-bound GLP-1R-Gs complexes
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    The conserved MASRPF motif in the Attractin homolog, Distracted, is required for association with Drosophila E3-ligase Mgrn1
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  50. Jun 2021
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    Age-related neuroinflammation and pathology in the locus coeruleus and hippocampus: beta-adrenergic antagonists exacerbate impairment of learning and memory in aged mice
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  61. May 2021
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    Systematic Functional Analysis of SARS-CoV-2 Proteins Uncovers Viral Innate Immune Antagonists and Remaining Vulnerabilities
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    PIWI proteomics identifies Atari and Pasilla as piRNA biogenesis factors in Aedes mosquitoes
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  67. Apr 2021
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    The Nuclear Receptor ESRRA Protects from Kidney Disease by Coupling Metabolism and Differentiation
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    An Activity-Guided Map of Electrophile-Cysteine Interactions in Primary Human T Cells
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    IL6/STAT3 Signaling Hijacks Estrogen Receptor α Enhancers to Drive Breast Cancer Metastasis
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    Huntingtin-mediated axonal transport requires arginine methylation by PRMT6
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    Argonaute-CLIP delineates versatile, functional RNAi networks in Aedes aegypti, a major vector of human viruses
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    Omnitemporal choreographies of all five STIM/Orai and IP3Rs underlie the complexity of mammalian Ca2+ signaling
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    Short antisense oligonucleotides alleviate the pleiotropic toxicity of RNA harboring expanded CGG repeats
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    Adenosine A2A receptor (A2AR) stimulation enhances mitochondrial metabolism and mitigates reactive oxygen species‐mediated mitochondrial injury
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    Poison Exon Splicing Regulates a Coordinated Network of SR Protein Expression during Differentiation and Tumorigenesis
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  91. Nov 2020
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    Chronic GPER1 Activation Protects Against Oxidative Stress-Induced Cardiomyoblast Death via Preservation of Mitochondrial Integrity and Deactivation of Mammalian Sterile-20-Like Kinase/Yes-Associated Protein Pathway
    1
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      DOI: 10.3389/fendo.2020.579161

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  93. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Enzymatic Activity of CD73 Modulates Invasion of Gliomas via Epithelial–Mesenchymal Transition-Like Reprogramming
    1
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      goat-anti-mouse

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  94. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Loss of Muscle Carnitine Palmitoyltransferase 2 Prevents Diet-Induced Obesity and Insulin Resistance despite Long-Chain Acylcarnitine Accumulation
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  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of ubiquitin Ser57 kinases regulating the oxidative stress response in yeast
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      DOI: 10.7554/eLife.58155

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  96. Oct 2020
  97. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Heparan sulfate proteoglycan‐mediated dynamin‐dependent transport of neural stem cell exosomes in an in vitro blood‐brain barrier model
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  98. www.sciencedirect.com www.sciencedirect.com
    EB1 Directly Regulates APC-Mediated Actin Nucleation
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  99. Sep 2020
  100. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Single‐cell RNA sequencing study of retinal immune regulators identified CD47 and CD59a expression in photoreceptors—Implications in subretinal immune regulation
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      DOI: 10.1002/jnr.24618

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    A Family of Argonaute-Interacting Proteins Gates Nuclear RNAi
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  102. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    BRD4 Prevents R-Loop Formation and Transcription-Replication Conflicts by Ensuring Efficient Transcription Elongation
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    Structure-Based Identification and Functional Characterization of a Lipocalin in the Malaria Parasite Plasmodium falciparum
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    Cathepsin S Regulates Antigen Processing and T Cell Activity in Non-Hodgkin Lymphoma
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  105. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Impairing committed cholesterol biosynthesis in white matter astrocytes, but not grey matter astrocytes, enhances in vitro myelination
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      DOI: 10.1111/jnc.15113

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    CCDC57 Cooperates with Microtubules and Microcephaly Protein CEP63 and Regulates Centriole Duplication and Mitotic Progression
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      DOI: 10.1016/j.celrep.2020.107630

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    Diapedesis-Induced Integrin Signaling via LFA-1 Facilitates Tissue Immunity by Inducing Intrinsic Complement C3 Expression in Immune Cells
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    Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19
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      DOI: 10.1016/j.cell.2020.04.026

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    GABAergic neurons in the insular cortex play an important role in cue-morphine reward memory reconsolidation
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      AB_10956588

      DOI: 10.1016/j.lfs.2020.117655

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    Global Landscape and Dynamics of Parkin and USP30-Dependent Ubiquitylomes in iNeurons during Mitophagic Signaling
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      RRID:AB_10956588

      DOI: 10.1016/j.molcel.2019.11.013

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    A Switch in p53 Dynamics Marks Cells That Escape from DSB-Induced Cell Cycle Arrest
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      RRID:AB_10956588

      DOI: 10.1016/j.celrep.2020.107995

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  112. elifesciences.org elifesciences.org
    The orphan receptor GPR88 blunts the signaling of opioid receptors and multiple striatal GPCRs
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      RRID:AB_10956588

      DOI: 10.7554/eLife.50519

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    Dopamine Uses the DRD5-ARRB2-PP2A Signaling Axis to Block the TRAF6-Mediated NF-κB Pathway and Suppress Systemic Inflammation
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      RRID:AB_10956588

      DOI: 10.1016/j.molcel.2020.01.022

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  114. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mouse brain transcriptome responses to inhaled nanoparticulate matter differed by sex and APOE in Nrf2-Nfkb interactions
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      RRID:AB_10956588

      DOI: 10.7554/eLife.54822

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  115. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    BET, SRC, and BCL2 family inhibitors are synergistic drug combinations with PARP inhibitors in ovarian cancer
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      AB_10956588

      DOI: 10.1016/j.ebiom.2020.102988

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    Protein O-GlcNAc Modification Links Dietary and Gut Microbial Cues to the Differentiation of Enteroendocrine L Cells
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      DOI: 10.1016/j.celrep.2020.108013

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    Fyn Kinase Controls Tau Aggregation In Vivo
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      RRID:AB_10956588

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    RBM45 associates with nuclear stress bodies and forms nuclear inclusions during chronic cellular stress and in neurodegenerative diseases
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      RRID:AB_10956588

      DOI: 10.1186/s40478-020-00965-y

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    The Autophagy-Initiating Kinase ULK1 Controls RIPK1-Mediated Cell Death
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      RRID:AB_10956588

      DOI: 10.1016/j.celrep.2020.107547

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    The Alazami Syndrome-Associated Protein LARP7 Guides U6 Small Nuclear RNA Modification and Contributes to Splicing Robustness
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    Chaperone-Mediated Protein Disaggregation Triggers Proteolytic Clearance of Intra-nuclear Protein Inclusions
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    FKBP10 Regulates Protein Translation to Sustain Lung Cancer Growth
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    S-phase-independent silencing establishment in Saccharomyces cerevisiae
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      DOI: 10.7554/eLife.58910

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    G3BP1 Is a Tunable Switch that Triggers Phase Separation to Assemble Stress Granules
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    Quantifying the Central Dogma in the p53 Pathway in Live Single Cells
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      IRDye 680RD Goat anti-Mouse IgG SecondaryAntibody

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  126. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Doa10 is a membrane protein retrotranslocase in ER-associated protein degradation
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    Deletion of 2‐aminoadipic semialdehyde synthase limits metabolite accumulation in cell and mouse models for glutaric aciduria type 1
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  128. www.jbc.org www.jbc.org
    Antibody Validation for Western blot: By the User, for the User
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  129. www.cell.com www.cell.com
    A Genome-wide ER-phagy Screen Highlights Key Roles of Mitochondrial Metabolism and ER-Resident UFMylation
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    Selective PP2A Enhancement through Biased Heterotrimer Stabilization
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    Small Molecule Dysregulation of TEAD Lipidation Induces a Dominant-Negative Inhibition of Hippo Pathway Signaling
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    Oncogenic Biogenesis of pri-miR-17∼92 Reveals Hierarchy and Competition among Polycistronic MicroRNAs
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    The Bromodomain Protein 4 Contributes to the Regulation of Alternative Splicing
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    IFI16 Targets the Transcription Factor Sp1 to Suppress HIV-1 Transcription and Latency Reactivation
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    Activity-Dependent Nucleation of Dynamic Microtubules at Presynaptic Boutons Controls Neurotransmission
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    EGFR-Pak Signaling Selectively Regulates Glutamine Deprivation-Induced Macropinocytosis
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    The Oncogenic Action of NRF2 Depends on De-glycation by Fructosamine-3-Kinase
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    Astrocyte‐specific transcriptome analysis using the ALDH1L1 bacTRAP mouse reveals novel biomarkers of astrogliosis in response to neurotoxicity
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    Recurrent SMARCB1 Mutations Reveal a Nucleosome Acidic Patch Interaction Site That Potentiates mSWI/SNF Complex Chromatin Remodeling
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    Small-Molecule and CRISPR Screening Converge to Reveal Receptor Tyrosine Kinase Dependencies in Pediatric Rhabdoid Tumors
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    Discovery and Characterization of a Cellular Potent Positive Allosteric Modulator of the Polycomb Repressive Complex 1 Chromodomain, CBX7
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    Anti-tumor Activity of the Type I PRMT Inhibitor, GSK3368715, Synergizes with PRMT5 Inhibition through MTAP Loss
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    53BP1 Enforces Distinct Pre- and Post-resection Blocks on Homologous Recombination
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    Mutual Zonated Interactions of Wnt and Hh Signaling Are Orchestrating the Metabolism of the Adult Liver in Mice and Human
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    A Consensus Binding Motif for the PP4 Protein Phosphatase
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    A Compendium of Genetic Modifiers of Mitochondrial Dysfunction Reveals Intra-organelle Buffering
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    A Genome-wide CRISPR Screen Identifies ZCCHC14 as a Host Factor Required for Hepatitis B Surface Antigen Production
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    Neuroprotective activity of leukemia inhibitory factor is relayed through myeloid zinc finger-1 in a rat model of stroke
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    Small-Molecule Inhibition of the UNC-Src Interaction Impairs Dynamic Src Localization in Cells
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    SLC19A1 Is an Importer of the Immunotransmitter cGAMP
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    Superior efficacy of cotreatment with BET protein inhibitor and BCL2 or MCL1 inhibitor against AML blast progenitor cells
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    TEX264 Is an Endoplasmic Reticulum-Resident ATG8-Interacting Protein Critical for ER Remodeling during Nutrient Stress
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    Absence of the Spindle Assembly Checkpoint Restores Mitotic Fidelity upon Loss of Sister Chromatid Cohesion
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    The Helicase PIF1 Facilitates Resection over Sequences Prone to Forming G4 Structures
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    Proteomics, Post-translational Modifications, and Integrative Analyses Reveal Molecular Heterogeneity within Medulloblastoma Subgroups
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