2,814 Matching Annotations
  1. Jan 2026
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    Yangjing Zhongyu decoction ameliorates polycystic ovary syndrome via multi-organ ferroptosis inhibition: A mechanistic study
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    sciencedirect.com/science/article/pii/S0378874126000371
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    Bacterial metabolites induce cell wall remodeling, antifungal resistance, and immune recognition of commensal fungi
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    sciencedirect.com/science/article/pii/S0960982225016781
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    Immune gene diversity and STING1 variants in shaping cancer immunity across different genetic ancestry populations
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    pmc.ncbi.nlm.nih.gov/articles/PMC13019158/
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    Uncovering genetic interactions in the DNA repair network in response to endogenous damage and ionizing radiation
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    sciencedirect.com/science/article/pii/S2211124725016225
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    Glycolysis inhibition functionally reprograms T follicular helper cells and reverses lupus
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    pmc.ncbi.nlm.nih.gov/articles/PMC12812013/
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    Optimized selection of specific antibodies against rodent ESR1 proteins and their application for immunohistochemistry and dual immunohistofluorescence with the specific anti-ESR2 antibody PPZ0506
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    pmc.ncbi.nlm.nih.gov/articles/PMC12811342/
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    GH Alters Lymphatic Vessels in Female Mice and STAT5 Phosphorylation in Human Lymphatic Endothelial Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12813289/
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    2026.01.11.698831v1.full-html.html
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    NF1 Loss Remodels Tumor Niches for Immune Evasion
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    Cell-Penetrating Peptide-Mediated siRNA Targeting of LDHC Suppresses Tumor Growth in a Triple-Negative Breast Cancer Zebrafish Xenograft Model
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    Cytoarchitectural multi-depot profiling reveals immune-metabolic crosstalk in human colon-associated adipose tissue
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    Microenvironmental TGF-β is an early driver of NF1-associated tumor formation
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    HBx hijacks the miR-19a-3p/BAMBI/TGF-β1 axis to impair the anti-tumour activity of CD4+ T cells in diffuse large B-cell lymphoma
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    Reverse molecular pharmacology identifies the non-canonical axis of IRAK as a chemoresistance factor in neuroblastoma
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    Early-life cognitive intervention preserves brain function in aged TgF344-AD rats with sex-specific effects
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    The ionotropic AMPA receptor contributes to autoimmunity via altered regulatory T cell differentiation
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    Structure of the lysosomal KICSTOR-GATOR1-SAMTOR nutrient-sensing supercomplex
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    In vivo detection of immune responses via cytokine activity labeling
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    Cldn11 deficiency aggravates osteoarthritis by inhibiting Notch signalling in a Tspan5-dependent manner
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    Aberrant nuclear pore complex degradation contributes to neurodegeneration in VCP disease
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    RNA-coupled CRISPR screens reveal ZNF207 as a regulator of LMNA aberrant splicing in progeria
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    Structure of pancreatic hIAPP fibrils derived from patients with type 2 diabetes
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    FOCAS: Transcriptome-wide screening of individual m6A sites functionally dissects epitranscriptomic control of gene expression in cancer
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    Extracellular GPX4 impairs antitumor immunity via dendritic ZP3 receptors
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  29. Dec 2025
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    BLF Stimulates Neuronal Differentiation via Activation of p35/CDK5 signaling and AMPK-Mediated Mitochondrial Regulation
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    Anti-mitotic agent SB-216 overcomes taxane resistance in castration-resistant prostate cancer and exhibits anti-tumour efficacy in pancreatic cancer
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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.70294
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    Pharmacologic reversal of advanced Alzheimer’s disease in mice and identification of potential therapeutic nodes in human brain
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    Mitochondrial VHL rewires cell metabolism in hypoxia
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    Hepatic adaptation to chronic metabolic stress primes tumorigenesis
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    Testosterone-induced metabolic changes in seminal vesicle epithelium modify seminal plasma components with potential to improve sperm motility
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    RAS mutation–specific responses to paralog- and state-selective RAS inhibitors
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    Enhanced non-enzymatic H2S generation extends lifespan and healthspan in male mice
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    Structure of the TXNL1-bound proteasome
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    Immune‐Related Protein and Non‐Coding RNA Cargo of Extracellular Vesicles Participate in the Chronic Inflammation Induced by HIV Infection
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    Different effects of 3-week disuse on the phenotype and gene expression of the calf and thigh muscles
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    biorxiv.org/content/10.64898/2025.12.04.691987v1
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    Extracellular Vesicles Favor Early Peripheral Immunosenescence Through Modulation of the Senescence-Associated Secretory Phenotype in HIV Infection
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    onlinelibrary.wiley.com/doi/full/10.1111/acel.70320
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    CDK4/6 inhibition reprograms the breast cancer immunopeptidome via Rb-dependent chromatin and transcriptomic remodeling
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    The exit of naive pluripotency contains a metabolism-induced checkpoint for telomere homeostasis
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    Purmorphamine exerts anti-obesity effects by enhancing secretin-activated brown fat thermogenesis
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    Hippocampal synaptic plasticity impairment and melatonin synthesis reduction in cognitive decline of a rodent model of Alzheimer’s disease-like pathology
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    link.springer.com/article/10.1007/s00424-025-03134-z
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    Spatiotemporal profiling of endocytic regulators in the immunosuppressive TAM microenvironment of glioma
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    Deep learning reveals endogenous sterols as allosteric modulators of the GPCR–Gα interface
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    Sensitized mast cells for targeted drug delivery and augmented cancer immunotherapy
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    IGF2BP1 fosters an immunosuppressive tumor microenvironment in high-risk neuroblastoma, contributing to their resistance to immunotherapy
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    tandfonline.com/doi/abs/10.1080/2162402X.2025.2584408
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    APLP1 Interacts with SARM1 and Regulates Axonal Maintenance and Post-Injury Degeneration
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    IGF2BP1 fosters an immunosuppressive tumor microenvironment in high-risk neuroblastoma, contributing to their resistance to immunotherapy
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    NAT10 promotes cancer metastasis by modulating p300/CBP activity through chromatin-associated tRNA
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    Interleukin-1/Toll-like receptor signaling potentiates macrophage olfactory receptor 2-driven atherosclerosis
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    Pharmacogenomic synthetic lethal screens reveal hidden vulnerabilities and new therapeutic approaches for treatment of NF1-associated tumors
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    Inhibition of ErbB2 mitigates secondary denervation after traumatic muscle injury
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    Cadherin-1-mediated communication at the leader-follower boundary controls mouse breast tumor organoid collective migration
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    pTα enhances mRNA translation and potentiates CAR T cells for solid tumor eradication
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  62. Nov 2025
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    A triple-action PROTAC for wild-type p53 cancer therapy
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    A 16-amino acid peptide delays the progression of motor neuron degeneration and pathogenic symptoms in ALS models
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    Biased histamine signaling selectively gates fat preference
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    Spring-like mechanics enable rapid inactivation and stochastic single-channel gating of the mechanically activated PIEZO channel
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    Harnessing the E3 ligase SPOP for targeted degradation of the NUP98::KDM5A fusion oncoprotein
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    Identification of a common ketohexokinase-dependent link driving alcohol intake and alcohol-associated liver disease in mice
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    RhoA allosterically activates phospholipase Cε via its EF hands
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    System analysis links SMARCD3 regulons to growth signaling and MEK inhibitor response in everolimus-resistant ER+ breast cancer cells
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    UMP functions as an endogenous regulator of NR4A1 to control gastric cancer progression
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    Herpes simplex virus type 1 disseminates from the cornea to the CNS in mice by thwarting type III interferon immune defenses
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    MIAT-DHX9 spatiotemporal expression drives venous neointimal hyperplasia through nucleolar homeostasis and mitotic progression
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    Targeting plasticity in the pyrimidine synthesis pathway potentiates macrophage-mediated phagocytosis in pancreatic cancer models
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    Repurposing Nelfinavir: AIM2 Inflammasome-Driven Anti-tumor Effects in Glioblastoma
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    Novel compounds with promising HuH-7 inhibitory activity as new cancer drug candidates: derivatives of N,N′-diphenylurea linked with 1,2,3-triazole
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    Dynasore as a dual modulator of lipid rafts and cell death in pancreatic cancer
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    Control of aging-associated neurodegeneration via hypothalamic extracellular vesicles containing parathymosin
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    Biallelic variants in the UTRN gene cause a novel form of multiple congenital arthrogryposis
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    Non-orthosteric inhibition of enolase 1 impedes growth of triple-negative breast cancer
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    Monitoring the complexity and dynamics of mitochondrial translation
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    An engineered cysteine sensor optimized for high-throughput screening identifies regulators of intracellular thiol levels
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    ID1 boosts antiviral immunity by countering PRMT5-mediated STING methylation
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