523 Matching Annotations
  1. Jul 2023
  2. www.sciencedirect.com www.sciencedirect.com
    A p53/LINC00324 positive feedback loop suppresses tumor growth by counteracting SET-mediated transcriptional repression
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    1. scibot 27 Jul 2023
      RRID:AB_2107436

      DOI: 10.1016/j.celrep.2023.112833

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    sciencedirect.com/science/article/pii/S2211124723008446
  3. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comparative transcriptome profiling of Eimeria tenella in various developmental stages and functional analysis of an ApiAP2 transcription factor exclusively expressed during sporogony
    1
    1. scibot 21 Jul 2023
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      DOI: 10.1186/s13071-023-05828-8

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    ncbi.nlm.nih.gov/pmc/articles/PMC10354945/
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    AAV-GRN partially corrects motor deficits and ALS/FTLD-related pathology in Tmem106b-/-Grn-/- mice
    1
    1. scibot 15 Jul 2023
      RRID:AB_2107436

      DOI: 10.1016/j.isci.2023.107247

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    sciencedirect.com/science/article/pii/S258900422301324X
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    A Proximity Labeling Strategy Enables Proteomic Analysis of Inter-organelle Membrane Contacts
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    1. scibot 15 Jul 2023
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      DOI: 10.1016/j.isci.2023.107159

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    sciencedirect.com/science/article/pii/S2589004223012361
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    ALKBH5 causes retinal pigment epithelium anomalies and choroidal neovascularization in age-related macular degeneration via the AKT/mTOR pathway
    1
    1. scibot 13 Jul 2023
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      DOI: 10.1016/j.celrep.2023.112779

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    sciencedirect.com/science/article/pii/S2211124723007908
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Eph receptor A4 regulates motor neuron ferroptosis in spinal cord ischemia/reperfusion injury in rats
    2
    1. scibot 12 Jul 2023
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      DOI: 10.4103/1673-5374.369118

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    ncbi.nlm.nih.gov/pmc/articles/PMC10328289/
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    M2 macrophages mediate fibrotic scar formation in the early stages after cerebral ischemia in rats
    2
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    ncbi.nlm.nih.gov/pmc/articles/PMC10328259/
  9. 52.53.155.43 52.53.155.43
    Blocking an epitope of misfolded SOD1 ameliorates disease phenotype in a model of amyotrophic lateral sclerosis
    1
    1. scibot 07 Jul 2023
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      DOI: 10.1093/brain/awad222

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    Hepatic soluble epoxide hydrolase activity regulates cerebral Aβ metabolism and the pathogenesis of Alzheimer’s disease in mice
    1
    1. scibot 06 Jul 2023
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      DOI: 10.1016/j.neuron.2023.06.002

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    sciencedirect.com/science/article/pii/S0896627323004373
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    Glibenclamide promotes FGF21 secretion in interscapular BAT and attenuates depression-like behaviors in male mice with HFD-induced obesity
    1
    1. scibot 04 Jul 2023
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      DOI: 10.1016/j.lfs.2023.121900

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    sciencedirect.com/science/article/pii/S0024320523005350
  12. Jun 2023
  13. portlandpress.com portlandpress.com
    Akt2 deficiency alleviates oxidative stress in the heart and liver via upregulating SIRT6 during high-fat diet-induced obesity
    1
    1. scibot 30 Jun 2023
      RRID:AB_2107436

      DOI: 10.1042/CS20230433

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    portlandpress.com/clinsci/article/137/10/823/233046/Akt2-deficiency-alleviates-oxidative-stress-in-the
  14. 52.53.155.43 52.53.155.43
    Photobiomodulation inhibits the expression of chondroitin... : Neural Regeneration Research
    1
    1. scibot 29 Jun 2023
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    52.53.155.43/dad58a375d9642a594f52869b5ea1c99c9936ce5/Photobiomodulation_inhibits_the_expression_of.30-html.html
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    QKI shuttles internal m7G-modified transcripts into stress granules and modulates mRNA metabolism
    1
    1. scibot 28 Jun 2023
      RRID: AB_2107436

      DOI: 10.1016/j.cell.2023.05.047

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    sciencedirect.com/science/article/pii/S0092867423005986
  16. www.sciencedirect.com www.sciencedirect.com
    Suppression of TREX1 Deficiency-Induced Cellular Senescence and Interferonopathies by Inhibition of DNA Damage Response
    1
    1. scibot 27 Jun 2023
      RRID:AB_2107436

      DOI: 10.1016/j.isci.2023.107090

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    sciencedirect.com/science/article/pii/S2589004223011677
  17. www.embopress.org www.embopress.org
    A coordinated multiorgan metabolic response contributes to human mitochondrial myopathy
    1
    1. scibot 24 Jun 2023
      RRID: AB_2107436

      DOI: 10.15252/emmm.202216951

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    embopress.org/doi/full/10.15252/emmm.202216951
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Uterine-specific Ezh2 deletion enhances stromal cell senescence and impairs placentation, resulting in pregnancy loss
    1
    1. scibot 24 Jun 2023
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      DOI: 10.1016/j.isci.2023.107028

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    ncbi.nlm.nih.gov/pmc/articles/PMC10285549/
  19. www.sciencedirect.com www.sciencedirect.com
    Establishing SARS-CoV-2 membrane protein-specific antibodies as a valuable serological target via high-content microscopy
    1
    1. scibot 23 Jun 2023
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      DOI: 10.1016/j.isci.2023.107056

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    sciencedirect.com/science/article/pii/S2589004223011331
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    Cooperative sensing of mitochondrial DNA by ZBP1 and cGAS promotes cardiotoxicity
    1
    1. scibot 23 Jun 2023
      RRID:AB_2107436

      DOI: 10.1016/j.cell.2023.05.039

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    sciencedirect.com/science/article/pii/S0092867423005913
  21. www.sciencedirect.com www.sciencedirect.com
    METTL14 regulates chromatin bivalent domains in mouse embryonic stem cells
    1
    1. scibot 22 Jun 2023
      RRID:AB_2107436

      DOI: 10.1016/j.celrep.2023.112650

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    sciencedirect.com/science/article/pii/S2211124723006617
  22. www.sciencedirect.com www.sciencedirect.com
    Immunosensitivity mediated by downregulated AKT1-SKP2 induces anti-PD-1-associated thyroid immune injury
    1
    1. scibot 16 Jun 2023
      RRID:AB_2107436

      DOI: 10.1016/j.intimp.2023.110452

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    sciencedirect.com/science/article/pii/S1567576923007750
  23. www.sciencedirect.com www.sciencedirect.com
    Acetylation halts missense mutant p53 aggregation and rescues tumor suppression in non-small cell lung cancers
    1
    1. scibot 16 Jun 2023
      RRID:AB_2107436

      DOI: 10.1016/j.isci.2023.107003

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    sciencedirect.com/science/article/pii/S2589004223010805
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Pathophysiology of COVID-19 and SARS-CoV-2 Infection: An alternative mechanism for skeletal muscle dysfunction in long-term post-viral lung disease
    1
    1. scibot 14 Jun 2023
      RRID:AB_2107436

      DOI: 10.1152/ajplung.00338.2022

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    ncbi.nlm.nih.gov/pmc/articles/PMC10259859/
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    Generation of a homozygous RANGRF knockout hiPSC line by CRISPR/ Cas9 system
    1
    1. scibot 09 Jun 2023
      RRID:AB_2107436

      DOI: 10.1016/j.scr.2023.103136

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    sciencedirect.com/science/article/pii/S1873506123001228
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The m6A Reader YTHDF2 Promotes Bladder Cancer Progression by Suppressing RIG-I–Mediated Immune Response
    1
    1. scibot 07 Jun 2023
      RRID:AB_2107436

      DOI: 10.1158/0008-5472.CAN-22-2485

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    ncbi.nlm.nih.gov/pmc/articles/PMC10236158/
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Serum response factor promotes axon regeneration following spinal cord transection injury
    1
    1. scibot 03 Jun 2023
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    ncbi.nlm.nih.gov/pmc/articles/PMC10233768/
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genetic modification of miR-34a enhances efficacy of transplanted human dental pulp stem cells after ischemic stroke
    1
    1. scibot 03 Jun 2023
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      DOI: 10.4103/1673-5374.367831

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    ncbi.nlm.nih.gov/pmc/articles/PMC10233773/
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    miR-181b promotes angiogenesis and neurological function recovery after ischemic stroke
    1
    1. scibot 03 Jun 2023
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      DOI: 10.4103/1673-5374.367957

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    ncbi.nlm.nih.gov/pmc/articles/PMC10233761/
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Tumor-suppressive Molecular Axis EP300/circRERE/miR-6837-3p/MAVS Activates Type I IFN Pathway and Antitumor Immunity to Suppress Colorectal Cancer
    1
    1. scibot 03 Jun 2023
      RRID:AB_2107436

      DOI: 10.1158/1078-0432.CCR-22-3836

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    ncbi.nlm.nih.gov/pmc/articles/PMC10233356/
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    SETD7 promotes lateral plate mesoderm formation by modulating the Wnt/β-catenin signaling pathway
    1
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      DOI: 10.1016/j.isci.2023.106917

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    Cadmium-induced Sertoli cell injury through p38-MAPK and related signaling proteins – a study by RNA sequencing
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      DOI: 10.1210/endocr/bqad045

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    academic.oup.com/endo/article/164/6/bqad045/7079002
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    Methionine restriction promotes cGAS activation and chromatin untethering through demethylation to enhance antitumor immunity
    1
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      DOI: 10.1016/j.ccell.2023.05.005

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    sciencedirect.com/science/article/pii/S1535610823001733
  34. May 2023
  35. www.sciencedirect.com www.sciencedirect.com
    Zhx2 maintains islet β cell mass and function by transcriptionally regulating Pax6
    1
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      DOI: 10.1016/j.isci.2023.106871

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    sciencedirect.com/science/article/pii/S2589004223009483
  36. www.biorxiv.org www.biorxiv.org
    FAM210A Regulates Mitochondrial Translation and Maintains Cardiac Mitochondrial Homeostasis
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      DOI: 10.1101/2023.05.20.541585

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    biorxiv.org/content/10.1101/2023.05.20.541585v1
  37. www.nature.com www.nature.com
    ERK and USP5 govern PD-1 homeostasis via deubiquitination to modulate tumor immunotherapy
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      DOI: 10.1038/s41467-023-38605-3

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    nature.com/articles/s41467-023-38605-3
  38. www.sciencedirect.com www.sciencedirect.com
    MYO10 regulates genome stability and cancer inflammation through mediating mitosis
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      DOI: 10.1016/j.celrep.2023.112531

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    sciencedirect.com/science/article/pii/S2211124723005429
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Establishment of highly metastatic ovarian cancer model with omental tropism via in vivo selection
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      DOI: 10.1016/j.isci.2023.106719

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    ncbi.nlm.nih.gov/pmc/articles/PMC10183668/
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    Circulating exosomes from patients with Graves’ disease induce an inflammatory immune response
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      DOI: 10.1210/endocr/bqaa236

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    academic.oup.com/endo/article/162/3/bqaa236/6046189
  41. 52.53.155.43 52.53.155.43
    mcr-22-1012-html.html
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    1. scibot 11 May 2023
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      DOI: 10.1158/1541-7786.MCR-22-1012

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    Characterization of an allosteric inhibitor of fungal-specific C-24 sterol methyltransferase to treat Candida albicans infections
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    Repositioning Lomitapide to block ZDHHC5-dependant palmitoylation on SSTR5 leads to anti-proliferation effect in preclinical pancreatic cancer models
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    VPS35 promotes cell proliferation via EGFR recycling and enhances EGFR inhibitors response in gastric cancer
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    Loss of C3a and C5a receptors promotes adipocyte browning and attenuates diet-induced obesity via activating inosine/A2aR pathway
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    Stabilization of nuclear β-catenin by inhibiting KDM2A mediates cerebral ischemic tolerance
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    Intrahippocampal injection of IL-1β upregulates Siah1-mediated degradation of synaptophysin by activation of the ERK signaling in male rat
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  89. Jan 2023
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    Decoding m6A RNA methylome identifies PRMT6-regulated lipid transport promoting AML stem cell maintenance
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    Yishen Xiezhuo formula ameliorates the development of cisplatin-induced acute kidney injury by attenuating renal tubular epithelial cell senescence
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    Intersection of immune and oncometabolic pathways drives cancer hyperprogression during immunotherapy
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    Inhibition of interaction between ROCK1 and Rubicon restores autophagy in endothelial cells and attenuates brain injury after prolonged ischemia
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    SETDB1 Restrains Endogenous Retrovirus Expression and Antitumor Immunity during Radiotherapy
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    Disrupting Circadian Rhythm via the PER1–HK2 Axis Reverses Trastuzumab Resistance in Gastric Cancer
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    Ischemic accumulation of succinate induces Cdc42 succinylation and inhibits neural stem cell proliferation after cerebral ischemia/reperfusion
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    Decreased expression of EZH2 in granulosa cells contributes to endometriosis-associated infertility by targeting IL-1R2
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    Alternative transcribed 3' isoform of long non-coding RNA Malat1 inhibits mouse retinal oxidative stress
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    Centrosomal Protein 120 Promotes Centrosome Amplification And Gastric Cancer Progression Via USP54-Mediated Deubiquitination Of PLK4
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    The deubiquitinase OTUD1 noncanonically suppresses Akt activation through its N-terminal intrinsically disordered region
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  101. Dec 2022
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    DNA damage repair kinase DNA-PK and cGAS synergize to induce cancer-related inflammation in glioblastoma
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    Allosteric Inhibition of c-Abl to Induce Unfolded Protein Response and Cell Death in Multiple Myeloma
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    Immunological profiles of human oligodendrogliomas define two distinct molecular subtypes
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    TGF-β2 Regulates Transcription of the K+/Cl− Cotransporter 2 (KCC2) in Immature Neurons and Its Phosphorylation at T1007 in Differentiated Neurons
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    Copper transporter gene ATP7A: A predictive biomarker for immunotherapy and targeted therapy in hepatocellular carcinoma
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    Social deficits via dysregulated Rac1-dependent excitability control of prefrontal cortical neurons and increased GABA/glutamate ratios
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    Tim-4 reprograms cholesterol metabolism to suppress antiviral innate immunity by disturbing the Insig1-SCAP interaction in macrophages
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    Dynamic quality control machinery that operates across compartmental borders mediates the degradation of mammalian nuclear membrane proteins
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    circPRKAA1 activates a Ku80/Ku70/SREBP-1 axis driving de novo fatty acid synthesis in cancer cells
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    Parkinson’s disease-associated Leucine-rich repeat kinase regulates UNC-104-dependent axonal transport of Arl8-positive vesicles in Drosophila
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    m6A modification of circSPECC1 suppresses RPE oxidative damage and maintains retinal homeostasis
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    Lactobacillus reuteri normalizes altered fear memory in male Cntnap4 knockout mice
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    Driving axon regeneration by orchestrating neuronal and non-neuronal innate immune responses via the IFNγ-cGAS-STING axis
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    Disease-associated mutations in WDR34 lead to diverse impacts on the assembly and function of dynein-2
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    Targeting the MITF/APAF-1 axis as salvage therapy for MAPK inhibitors in resistant melanoma
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    Leukemia inhibitory factor is a therapeutic target for renal interstitial fibrosis
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    Cancer cell intrinsic TIM-3 induces glioblastoma progression
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    Acute depletion of human core nucleoporin reveals direct roles in transcription control but dispensability for 3D genome organization
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  124. Oct 2022
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    m6A modification confers thermal vulnerability to HPV E7 oncotranscripts via reverse regulation of its reader protein IGF2BP1 upon heat stress
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  171. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR/Cas9 Screens Reveal Epstein-Barr Virus Transformed B-Cell Host Dependency Factors
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  172. www.sciencedirect.com www.sciencedirect.com
    Capsaicin inhibits intestinal Cl- secretion and promotes Na+ absorption by blocking TRPV4 channels in healthy and colitic mice
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    DsbA-L interacts with VDAC1 in mitochondrion-mediated tubular cell apoptosis and contributes to the progression of acute kidney disease
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  174. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Intermittent bolus feeding does not enhance protein synthesis, myonuclear accretion, or lean growth more than continuous feeding in a premature piglet model
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    Moderate heart rate reduction promotes cardiac regeneration through stimulation of the metabolic pattern switch
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  176. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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    Dynamic control of chromatin-associated m6A methylation regulates nascent RNA synthesis
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  178. Feb 2022
  179. www.sciencedirect.com www.sciencedirect.com
    Substrate rigidity dictates colorectal tumorigenic cell stemness and metastasis via CRAD-dependent mechanotransduction
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  180. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    TBK1-METTL3 axis facilitates antiviral immunity
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    Suppression of premature transcription termination leads to reduced mRNA isoform diversity and neurodegeneration
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  182. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Nicotinamide N-methyltransferase ameliorates renal fibrosis by its metabolite 1-methylnicotinamide inhibiting the TGF-β1/Smad3 pathway
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  183. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Annexin A7 and JNK knockdown suppress the lymphatic metastasis potential of hepatocellular carcinoma cells: Possible contributions of ATF2 and sequence-related lncRNA NONMMUT114121.1
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    E3 ligase RNF167 and deubiquitinase STAMBPL1 modulate mTOR and cancer progression
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  185. Jan 2022
  186. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Elucidation of pathological mechanism caused by human disease mutation in CaMKIIβ
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    Generation of SCN5A heterozygous knock-out human induced pluripotent stem cell line by CRISPR/Cas9-mediated genome editing
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    Metastasis enhancer PGRMC1 boosts store-operated Ca2+ entry by uncoiling Ca2+ sensor STIM1 for focal adhesion turnover and actomyosin formation
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    WASH interacts with Ku to regulate DNA double-stranded break repair
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  190. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Generation and analysis of innovative genomically humanized knockin SOD1, TARDBP (TDP-43), and FUS mouse models
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    Withaferin A alleviates ethanol-induced liver injury by inhibiting hepatic lipogenesis
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    STING orchestrates the crosstalk between polyunsaturated fatty acid metabolism and inflammatory responses
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  193. onlinelibrary.wiley.com onlinelibrary.wiley.com
    E3 Ubiquitin Ligase Nedd4-2 Exerts Neuroprotective Effects During Endoplasmic Reticulum Stress
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  194. Dec 2021
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    Glucocorticoid receptor regulates PD-L1 and MHC-I in pancreatic cancer cells to promote immune evasion and immunotherapy resistance
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  196. Nov 2021
  197. academic.oup.com academic.oup.com
    Variations of C14ORF39 and SYCE1 identified in idiopathic premature ovarian insufficiency and nonobstructive azoospermia
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  198. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Proteomic Profiling of Astrocytic O-GlcNAc Transferase-Related Proteins in the Medial Prefrontal Cortex
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    The Y14-p53 regulatory circuit in megakaryocyte differentiation and thrombocytopenia
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    OGDHL Ameliorates Cognitive Impairment and Alzheimer's Disease-Like Pathology via Activating Wnt/β-catenin signaling in Alzheimer's Disease Mice
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    A general role for TANGO1, encoded by MIA3, in secretory pathway organization and function
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    LRG1 destabilizes tumor vessels and restricts immunotherapeutic potency
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    IRF3-binding lncRNA-ISIR strengthens interferon production in viral infection and autoinflammation
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  204. Oct 2021
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    Myosin 1f-mediated activation of microglia contributes to the photoreceptor degeneration in a mouse model of retinal detachment
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    An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity
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    Ordered assembly of the cytosolic RNA-sensing MDA5-MAVS signaling complex via binding to unanchored K63-linked poly-ubiquitin chains
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    A Novel Calpain Inhibitor Compound Has Protective Effects on a Zebrafish Model of Spinocerebellar Ataxia Type 3
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    Humanin alleviates insulin resistance in polycystic ovary syndrome: a human and rat model-based study
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  211. Aug 2021
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    Establishment of a second generation homozygous CRISPRa human induced pluripotent stem cell (hiPSC) line for enhanced levels of endogenous gene activation
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    Autophagic elimination of ribosomes during spermiogenesis provides energy for flagellar motility
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    ErbB4 mediates amyloid β-induced neurotoxicity through JNK/tau pathway activation: implications for Alzheimer’s disease
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