Hypothesis

1,070 Matching Annotations

Dec 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

ARID1A governs the silencing of sex-linked transcription during male meiosis in the mouse

14
1. scibot 14 Dec 2024
  
  in Public
  
  RRID:AB_2534088
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2534088
2. scibot 13 Dec 2024
  
  in Public
  
  RRID:AB_2534088
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2534088
3. scibot 12 Dec 2024
  
  in Public
  
  RRID:AB_2534088
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2534088
4. scibot 11 Dec 2024
  
  in Public
  
  RRID:AB_2534088
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2534088
5. scibot 10 Dec 2024
  
  in Public
  
  RRID:AB_2534088
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2534088
6. scibot 09 Dec 2024
  
  in Public
  
  RRID:AB_2534088
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2534088
7. scibot 08 Dec 2024
  
  in Public
  
  RRID:AB_2534088
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2534088
8. scibot 07 Dec 2024
  
  in Public
  
  RRID:AB_2534088
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2534088
9. scibot 06 Dec 2024
  
  in Public
  
  RRID:AB_2534088
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2534088
10. scibot 05 Dec 2024
  
  in Public
  
  RRID:AB_2534088
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2534088
11. scibot 04 Dec 2024
  
  in Public
  
  RRID:AB_2534088
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2534088
12. scibot 03 Dec 2024
  
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  RRID:AB_2534088
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2534088
13. scibot 02 Dec 2024
  
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  RRID:AB_2534088
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2534088
14. scibot 01 Dec 2024
  
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  RRID:AB_2534088
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11594533/
www.sciencedirect.com www.sciencedirect.com

Mitochondrial transplantation rescues Ca2+ homeostasis imbalance and myocardial hypertrophy in SLC25A3-related hypertrophic cardiomyopathy

1
1. scibot 14 Dec 2024
  
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  RRID:AB_2534088
  
  DOI: 10.1016/j.celrep.2024.115065
  
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sciencedirect.com/science/article/pii/S2211124724014165
www.cell.com www.cell.com

Fully biologic endothelialized-tissue-engineered vascular conduits provide antithrombotic function and graft patency

1
1. scibot 12 Dec 2024
  
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  RRID:AB_138404
  
  DOI: 10.1016/j.stem.2024.11.006
  
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cell.com/cell-stem-cell/abstract/S1934-5909(24)00406-5
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Classification and functional characterization of regulators of intracellular STING trafficking identified by genome-wide optical pooled screening

1
1. scibot 10 Dec 2024
  
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  RRID:AB_2534088
  
  DOI: 10.1016/j.cels.2024.11.004
  
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sciencedirect.com/science/article/pii/S2405471224003375
www.biorxiv.org www.biorxiv.org

Lysyl Oxidases are Necessary for Myometrial Contractility and On-Time Parturition in Mice

1
1. scibot 05 Dec 2024
  
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  RRID:AB_2534088
  
  DOI: 10.1101/2024.09.05.610344
  
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biorxiv.org/content/10.1101/2024.09.05.610344v1
52.53.155.43 52.53.155.43

TBC1D24 interacts with the v-ATPase and regulates intraorganellar pH in neurons

1
1. scibot 05 Dec 2024
  
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  RRID:AB_2534088
  
  DOI: 10.1016/j.isci.2024.111515
  
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52.53.155.43/a78570202c237c34caff8d9dcc5ffd9013c3700f/1-s2.0-S2589004224027421-main-html.html
Nov 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

ARID1A governs the silencing of sex-linked transcription during male meiosis in the mouse

2
1. scibot 29 Nov 2024
  
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  RRID:AB_2534088
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2534088
2. scibot 28 Nov 2024
  
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  RRID:AB_2534088
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11594533/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Orexin-A increases the differentiation of human olfactory sensory neurons through orexin receptor type 1

1
1. scibot 26 Nov 2024
  
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  RRID:AB_2534088
  
  DOI: 10.1016/j.reth.2024.10.014
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11585478/
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Profound synthetic lethality between SMARCAL1 and FANCM

1
1. scibot 17 Nov 2024
  
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  RRID:AB_2534088
  
  DOI: 10.1016/j.molcel.2024.10.016
  
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sciencedirect.com/science/article/pii/S1097276524008566
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Lysosomal damage triggers a p38 MAPK-dependent phosphorylation cascade to promote lysophagy via the small heat shock protein HSP27

1
1. scibot 14 Nov 2024
  
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  RRID:AB_2534088
  
  DOI: 10.1016/j.cub.2024.10.061
  
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sciencedirect.com/science/article/pii/S096098222401457X
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Systematic screens for fertility genes essential for malaria parasite transmission reveal conserved aspects of sex in a divergent eukaryote

1
1. scibot 14 Nov 2024
  
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  RRID:AB_2534088
  
  DOI: 10.1016/j.cels.2024.10.008
  
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sciencedirect.com/science/article/pii/S2405471224003053
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SNARE protein SNAP25 regulates the chloride-transporter KCC2 in neurons

1
1. scibot 10 Nov 2024
  
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  RRID:AB_2534088
  
  DOI: 10.1016/j.isci.2024.111156
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11539599/
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Active RNA synthesis patterns nuclear condensates

1
1. scibot 08 Nov 2024
  
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  RRID:AB_2534088
  
  DOI: 10.1101/2024.10.12.614958
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11533426/
elifesciences.org elifesciences.org

Integrative study of skeletal muscle mitochondrial dysfunction in a murine pancreatic cancer-induced cachexia model

1
1. scibot 07 Nov 2024
  
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  RRID:AB_2534088
  
  DOI: 10.7554/eLife.93312
  
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elifesciences.org/articles/93312
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Striatal cholinergic interneuron pause response requires Kv1 channels, is absent in dyskinetic mice, and is restored by dopamine D5 receptor inverse agonism

1
1. scibot 07 Nov 2024
  
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  RRID:AB_138404
  
  DOI: 10.7554/eLife.102184.1
  
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elifesciences.org/reviewed-preprints/102184
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Beyond Glycolysis: Aldolase A Is a Novel Effector in Reelin-Mediated Dendritic Development

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1. scibot 07 Nov 2024
  
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  RRID:AB_2534088
  
  DOI: 10.1523/JNEUROSCI.0072-24.2024
  
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jneurosci.org/content/44/42/e0072242024
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Synaptic gene expression is coordinated across development by conserved chromatin regulators

1
1. scibot 07 Nov 2024
  
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  RRID:AB_2534088
  
  DOI: 10.1101/2024.10.30.621128
  
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biorxiv.org/content/10.1101/2024.10.30.621128v1
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Olanzapine enhances early brain maturation through activation of the NODAL/FOXH1 axis

1
1. scibot 07 Nov 2024
  
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  RRID:AB_2534088
  
  DOI: 10.1016/j.isci.2024.110917
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11519431/
Oct 2024
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Inactive Parp2 causes Tp53-dependent lethal anemia by blocking replication-associated nick ligation in erythroblasts

1
1. scibot 09 Oct 2024
  
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  AB_2534088
  
  DOI: 10.1016/j.molcel.2024.09.020
  
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sciencedirect.com/science/article/pii/S1097276524007767
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PAR2 on oral cancer cells and nociceptors contributes to oral cancer pain that can be relieved by nanoparticle-encapsulated AZ3451

1
1. scibot 04 Oct 2024
  
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  DOI: 10.1016/j.biomaterials.2024.122874
  
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sciencedirect.com/science/article/pii/S0142961224004083
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Rift Valley fever virus coordinates the assembly of a programmable E3 ligase to promote viral replication

1
1. scibot 04 Oct 2024
  
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  AB_2534088
  
  DOI: 10.1016/j.cell.2024.09.008
  
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sciencedirect.com/science/article/pii/S0092867424010262
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PfSPZ Vaccine induces focused humoral immune response in HIV positive and negative Tanzanian adults

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1. scibot 02 Oct 2024
  
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  DOI: 10.1016/j.ebiom.2024.105364
  
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sciencedirect.com/science/article/pii/S2352396424004006
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Pervasive mislocalization of pathogenic coding variants underlying human disorders

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1. scibot 02 Oct 2024
  
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  AB_2534088
  
  DOI: 10.1016/j.cell.2024.09.003
  
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sciencedirect.com/science/article/pii/S0092867424010213
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Antagonistic nanobodies implicate mechanism of GSDMD pore formation and potential therapeutic application

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1. scibot 02 Oct 2024
  
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  DOI: 10.1038/s41467-024-52110-1
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11427689/
Sep 2024
onlinelibrary.wiley.com onlinelibrary.wiley.com

ProSAAS is preferentially up-regulated during homeostatic scaling and reduces amyloid plaque burden in the 5xFAD mouse hippocampus

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1. scibot 27 Sep 2024
  
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  DOI: 10.1111/jnc.16193
  
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onlinelibrary.wiley.com/doi/10.1111/jnc.16193
onlinelibrary.wiley.com onlinelibrary.wiley.com

Amyloid beta 1-40 and 1-42 fibril ratios and maturation level cause conformational differences with minimal impact on autophagy and cytotoxicity

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1. scibot 27 Sep 2024
  
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  DOI: 10.1111/jnc.16201
  
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onlinelibrary.wiley.com/doi/10.1111/jnc.16201
faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com

Katanin regulatory subunit B1 (KATNB1) regulates BTB dynamics through changes in cytoskeletal organization

1
1. scibot 27 Sep 2024
  
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  AB_2534088
  
  DOI: 10.1096/fj.202400966R
  
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faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202400966R
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Segregated basal ganglia output pathways correspond to genetically divergent neuronal subclasses

1
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  DOI: 10.1101/2024.08.28.610136
  
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Atypical cellular responses mediated by intracellular constitutive active TrkB (NTRK2) kinase domains and a solely intracellular NTRK2-fusion oncogene

1
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  RRID:AB_138404
  
  DOI: 10.1038/s41417-024-00809-0
  
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Microbiota regulates neonatal disease tolerance to virus-evoked necrotizing enterocolitis by shaping the STAT1-NLRC5 axis in the intestinal epithelium

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  DOI: 10.1016/j.chom.2024.08.013
  
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Postsynaptic and Presynaptic NMDARs Have Distinct Roles in Visual Circuit Development

1
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  RRID:AB_2534069
  
  DOI: 10.1016/j.celrep.2020.107955
  
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Kinetic Heterogeneity of Cancer Cell Fractional Killing

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Capture and display of antibodies secreted by hybridoma cells enables fluorescent on-cell screening

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  RRID:AB_2534088
  
  DOI: 10.1080/19420862.2019.1574520
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6512912/
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Brain Diffusivity and Structural Changes in the R6/2 Mouse Model of Huntington Disease

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  AB_143160
  
  DOI: 10.1002/jnr.23965
  
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onlinelibrary.wiley.com/doi/10.1002/jnr.23965/full
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Human induced pluripotent stem cell line (FDHSi005-A) derived from a patient with a deep intronic variant in the GNE gene

1
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  AB_2534088
  
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Generation of a fluorescent mNeonGreen insulin reporter line in the H1 (WA01) hESC background

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Reproducible Differentiation of Human Pluripotent Stem Cells into Two-Dimensional Cortical Neuron Cultures with Checkpoints for Success

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  DOI: 10.1002/cpz1.948
  
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currentprotocols.onlinelibrary.wiley.com/doi/10.1002/cpz1.948
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The function of juvenile–adult transition axis in female sexual receptivity of Drosophila melanogaster

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  DOI: 10.7554/eLife.92545
  
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A broadly applicable method for quantifying cardiomyocyte cell division identifies proliferative events following myocardial infarction

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  DOI: 10.1016/j.crmeth.2024.100860
  
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MOF-mediated PRDX1 acetylation regulates inflammatory macrophage activation

1
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  AB_2534088
  
  DOI: 10.1016/j.celrep.2024.114682
  
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The RNA-binding protein EIF4A3 promotes axon development by direct control of the cytoskeleton

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  AB_2534088
  
  DOI: 10.1016/j.celrep.2024.114666
  
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ALS-FUS mutations cause abnormal PARylation and histone H1.2 interaction, leading to pathological changes

1
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  AB_2534088
  
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TGM1/3-mediated transamidation of Exo70 promotes tumor metastasis upon LKB1 inactivation

1
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  DOI: 10.1016/j.celrep.2024.114604
  
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Generation of a human induced pluripotent stem cell line ZZUNEUi030-A from a female patient carrying a heterozygous CALM2 (c.395 A > T) mutation

1
1. scibot 21 Aug 2024
  
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  AB_2534088
  
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The divergent effects of G3BP orthologs on human stress granule assembly imply a centric role for the core protein interaction network

1
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  AB_2534088
  
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nemeth-et-al-2024-adiponectin-suppresses-stiffness-dependent-pro-fibrotic-activation-of-lung-fibroblasts-html.html

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  RRID:AB_138404
  
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52.53.155.43/b68deb9c62e0885cf46c9d0e6108ed17561f8fea/nemeth-et-al-2024-adiponectin-suppresses-stiffness-dependent-pro-fibrotic-activation-of-lung-fibroblasts-html.html
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Sugar-mediated non-canonical ubiquitination impairs Nrf1/NFE2L1 activation

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  AB_2534088
  
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Insect-transmitted plant virus balances its vertical transmission through regulating Rab1-mediated receptor localization

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  AB_2534088
  
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PMC10174194 S1 Table-html.html

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  DOI: 10.1083/jcb.202211074
  
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52.53.155.43/08461ce6dd864961f351a1d5fb7d3c9b768910e9/PMC10174194 S1 Table-html.html
academic.oup.com academic.oup.com

The adeno-associated virus 2 (AAV2) genome and rep 68/78 proteins interact with cellular sites of DNA damage

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  A11029
  
  DOI: 10.1093/hmg/ddab300
  
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academic.oup.com/hmg/advance-article-abstract/doi/10.1093/hmg/ddab300/6397801
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BDNF‐Gene Transfected Schwann Cell‐Assisted Axonal Extension and Sprouting on New PLA–PPy Microfiber Substrates

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  goat antimouse IgG Alexa Fluor 488
  
  DOI: 10.1002/mabi.202000391
  
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onlinelibrary.wiley.com/doi/full/10.1002/mabi.202000391
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Steroid hormones and human choriogonadotropin influence the distribution of alpha6-integrin and desmoplakin 1 in gland-like endometrial epithelial spheroids

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  Alexa Fluor 488 anti-mouse
  
  DOI: 10.1007/s00418-020-01960-z
  
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onlinelibrary.wiley.com onlinelibrary.wiley.com

Spatial patterning of excitatory and inhibitory neuropil territories during spinal circuit development

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  AB_2534088goat
  
  DOI: 10.1002/cne.24152
  
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onlinelibrary.wiley.com/doi/10.1002/cne.24152/full
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Table 2 Antibodies used for different experiments in this report.

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  AB_2534088
  
  DOI: 10.1038/s41419-020-2608-8
  
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Untitled document

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  DOI: 10.1038/s41419-017-0201-6
  
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nature.com/articles/s41419-017-0201-6/tables/1
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Generating a human induced pluripotent stem cell line (XACHi018-A) from a Timothy syndrome infant carrying heterozygous CACNA1C c.1216G>A (p.G406R) mutation

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  DOI: 10.1016/j.scr.2024.103513
  
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sciencedirect.com/science/article/pii/S1873506124002113
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Generation of induced pluripotent stem cell line (UCSFi001-A-77) carrying a biallelic frameshift variant in exon 4 of SGIP1 through CRISPR/Cas9

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  RRID:AB_2534088
  
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Generation of a gene-corrected human isogenic iPSC line from an Alzheimer’s disease iPSC line carrying the PSEN1 H163R mutation

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  RRID:AB_2534088
  
  DOI: 10.1016/j.scr.2024.103495
  
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Generation of an induced pluripotent stem cell line (BIORTCi001-A) from a healthy adult indigenous Nigerian participant

1
1. scibot 24 Jul 2024
  
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  RRID:AB_2534088
  
  DOI: 10.1016/j.scr.2024.103503
  
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sciencedirect.com/science/article/pii/S1873506124002010
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Ceramide-induced cleavage of GPR64 intracellular domain drives Ewing sarcoma

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  RRID:AB_2534088
  
  DOI: 10.1016/j.celrep.2024.114497
  
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cell.com/cell-reports/fulltext/S2211-1247(24)00826-X
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The splicing factor CCAR1 regulates the Fanconi anemia/BRCA pathway

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  RRID:AB_2534088
  
  DOI: 10.1016/j.molcel.2024.06.031
  
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Differences in male Aedes aegypti and Aedes albopictus hearing systems facilitate recognition of conspecific female flight tones

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Establishment of an induced pluripotent stem cell line from a patient with X-linked Alport syndrome carrying a hemizygous splicing variant (NM_033380; c.929[exon 16]delG) in the collagen type IV alpha 5 chain gene

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Microglial-derived C1q integrates into neuronal ribonucleoprotein complexes and impacts protein homeostasis in the aging brain

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BPS Publications

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  DOI: 10.1111/bph.16487
  
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Single-cell transcriptomics predict novel potential regulators of acute epithelial restitution in the ischemia-injured intestine

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  DOI: 10.1101/2024.06.28.601271
  
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Tissue Mechanics Regulate Mitotic Nuclear Dynamics during Epithelial Development

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Ube3a unsilencer for the potential treatment of Angelman syndrome

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  DOI: 10.1038/s41467-024-49788-8
  
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H19 influenza A virus exhibits species-specific MHC class II receptor usage

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EYA protein complex is required for Wntless retrograde trafficking from endosomes to Golgi

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Sonic Hedgehog activates prostaglandin signaling to stabilize primary cilium length

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Human SIRT5 variants with reduced stability and activity do not cause neuropathology in mice

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BPS Publications

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  D. Secondary antibodies used for immunoblotting or confocal imaging.Figure S4Figure S4. The selected pS129 antibodies recognize all specifically pS129-aSyn but notunmodified aSyn (related to Figure 2)A. Forty nanograms of human recombinant monomeric aSyn unphosphorylated (WT) or phosphorylatedat the S129 residue (pS129) were detected by WB using commercial antibodies (pSyn#64, MJF-R13,81a, EP1536Y and GTX) or the LASH-EGT homemade pS129 antibody (respective epitopes listed inFigure S3) combined with total aSyn antibodies (Fl-140 or SYN-1).B-C. Forty nanograms of human recombinant monomeric aSyn (WT) or phosphorylated at the Y39(pY39) or S87 (pS87) or S129 residues (pS129) and WB was performed using the pY39 antibody (B)
  
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Neuronal activity-driven O-GlcNAcylation promotes mitochondrial plasticity

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Viral infection disrupts intestinal homeostasis via Sting-dependent NF-κB signaling in Drosophila

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Axonal endoplasmic reticulum tubules control local translation via P180/RRBP1-mediated ribosome interactions

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Insights from multi-omic modeling of neurodegeneration in xeroderma pigmentosum using an induced pluripotent stem cell system

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The Neurog2-Tbr2 axis forms a continuous transition to the neurogenic gene expression state in neural stem cells

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Nuclear aggregates of NONO/SFPQ and A-to-I-edited RNA in Parkinson’s disease and dementia with Lewy bodies

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Generation of induced pluripotent stem cell lines from two unrelated patients affected by intellectual disability carrying homozygous variants in SGIP1

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Adult-Onset Deletion of ATP13A2 in Mice Induces Progressive Nigrostriatal Pathway Dopaminergic Degeneration and Lysosomal Abnormalities

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NRP1 is a receptor for mammalian orthoreovirus engaged by distinct capsid subunits

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PDZD8 promotes autophagy at ER-Lysosome contact sites to regulate synaptogenesis

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ProSAAS is Preferentially Secreted from Neurons During Homeostatic Scaling and Reduces Amyloid Plaque Size in the 5xFAD Mouse Hippocampus

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Cox7a1 controls skeletal muscle physiology and heart regeneration through complex IV dimerization

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The thalamic reticular nucleus orchestrates social memory

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ER-associated degradation adapter Sel1L is required for CD8+ T cell function and memory formation following acute viral infection

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Detection of ER Stress in iPSC-Derived Neurons Carrying the p.N370S Mutation in the GBA1 Gene

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Generation and characterization of six human induced pluripotent stem cell lines (hiPSCs) from three individuals with SSADH Deficiency and CRISPR-corrected isogenic controls

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Efficient generation of induced pluripotent stem cell lines from healthy donors’ peripheral blood mononuclear cells of different genders

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Reprogramming fibroblast into human iBlastoids

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Accumulation of APP C-terminal fragments causes endolysosomal dysfunction through the dysregulation of late endosome to lysosome-ER contact sites

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Time-series reconstruction of the molecular architecture of human centriole assembly

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Sustained type I interferon signaling after human immunodeficiency virus type 1 infection of human iPSC derived microglia and cerebral organoids

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Truncating NFKB1 variants cause combined NLRP3 inflammasome activation and type I interferon signaling and predispose to necrotizing fasciitis

2
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  DOI: 10.1016/j.xcrm.2024.101503
  
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  DOI: 10.1016/j.xcrm.2024.101503
  
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Map-1a regulates Sertoli cell BTB dynamics through the cytoskeletal organization of microtubule and F-actin

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  DOI: 10.1186/s12958-024-01204-y
  
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Statins inhibit protein kinase D (PKD) activation in intestinal cells and prevent PKD1-induced growth of murine enteroids

1
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  DOI: 10.1152/ajpcell.00286.2022
  
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Mar 2024
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Interaction between host G3BP and viral nucleocapsid protein regulates SARS-CoV-2 replication and pathogenicity

1
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  DOI: 10.1016/j.celrep.2024.113965
  
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Piezo1 mechanosensing regulates integrin-dependent chemotactic migration in human T cells

1
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  DOI: 10.7554/eLife.91903
  
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JAK-STAT pathway activation compromises nephrocyte function in a Drosophila high-fat diet model of chronic kidney disease

1
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  DOI: 10.1101/2024.03.07.583967
  
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A surge in cytoplasmic viscosity triggers nuclear remodeling required for Dux silencing and pre-implantation embryo development

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  DOI: 10.1016/j.celrep.2024.113917
  
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Disease-causing Slack potassium channel mutations produce opposite effects on excitability of excitatory and inhibitory neurons

1
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  DOI: 10.1016/j.celrep.2024.113904
  
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Age-related ciliopathy: Obesogenic shortening of melanocortin-4 receptor-bearing neuronal primary cilia

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  DOI: 10.1016/j.cmet.2024.02.010
  
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Securin acetylation prevents precocious separase activation and premature sister chromatid separation

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  DOI: 10.1016/j.cub.2024.02.038
  
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Generation of induced pluripotent stem cells (UCLi024-A) from a patient with argininosuccinate lyase deficiency carrying a homozygous c.437G > A (p.Arg146Gln) mutation

1
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The GATOR2 complex maintains lysosomal-autophagic function by inhibiting the protein degradation of MiT/TFEs

1
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KIF3A tail domain phosphorylation is not required for ciliogenesis in mouse embryonic fibroblasts

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Canonical Wnt signaling directs the generation of functional human PSC-derived atrioventricular canal cardiomyocytes in bioprinted cardiac tissues

1
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  DOI: 10.1016/j.stem.2024.01.008
  
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Generation of IPi001-A/B/C human induced pluripotent stem cell lines from healthy amniotic fluid cells

1
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  DOI: 10.1016/j.scr.2024.103350
  
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Generation of a TMEM43 knockout human induced pluripotent stem cell line (HDZi003-A-1) using CRISPR/Cas9

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Adhesion-clutch between DCC and netrin-1 mediates netrin-1–induced axonal haptotaxis

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  DOI: 10.3389/fnmol.2024.1307755
  
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The iron chelator and OXPHOS inhibitor VLX600 induces mitophagy and an autophagy-dependent type of cell death in glioblastoma cells

2
1. scibot 22 Feb 2024
  
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Complex formation of immunoglobulin superfamily molecules Side-IV and Beat-IIb regulates synaptic specificity

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Establishment of an induced pluripotent stem cell line from a Noonan syndrome patient with the heterozygote mutation p.S257L (c.770C>T) in RAF1 gene

1
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Metabolic rewiring and autophagy inhibition correct lysosomal storage disease in Mucopolysaccharidosis IIIB

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The iron chelator and OXPHOS inhibitor VLX600 induces mitophagy and an autophagy-dependent type of cell death in glioblastoma cells

3
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RNF4 prevents genomic instability caused by chronic DNA under-replication

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  DOI: 10.1016/j.dnarep.2024.103646
  
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Mechanical Netrin-1-DCC Coupling Mediates Netrin-1–induced Axonal Haptotaxis

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Genetic background variation impacts microglial heterogeneity and disease progression in amyotrophic lateral sclerosis model mice

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The androgen receptor interacts with GATA3 to transcriptionally regulate a luminal epithelial cell phenotype in breast cancer

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  DOI: 10.1186/s13059-023-03161-y
  
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Generation of the human induced pluripotent stem cell line PUMCi005-A from a patient with Perrault syndrome

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  RRID: AB138404
  
  DOI: 10.1016/j.scr.2024.103318
  
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Dual roles of CCDC102A in governing centrosome duplication and cohesion

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  DOI: 10.1016/j.celrep.2024.113696
  
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Evolution of human H3N2 influenza virus receptor specificity has substantially expanded the receptor-binding domain site

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  DOI: 10.1016/j.chom.2024.01.003
  
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An enriched environment ameliorates the reduction of parvalbumin-positive interneurons in the medial prefrontal cortex caused by maternal separation early in life

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  DOI: 10.3389/fnins.2023.1308368
  
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Characterization of a novel variant in the HR1 domain of MFN2 in a patient with ataxia, optic atrophy and sensorineural hearing loss

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  RRID:AB_138404
  
  DOI: 10.12688/f1000research.53230.2
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10808857/
Jan 2024
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Mapping of multiple neurotransmitter receptor subtypes and distinct protein complexes to the connectome

2
1. scibot 23 Jan 2024
  
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  DOI: 10.1016/j.neuron.2023.12.014
  
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2. scibot 23 Jan 2024
  
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  RRID:AB_2534088
  
  DOI: 10.1016/j.neuron.2023.12.014
  
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Notch receptor-ligand binding facilitates extracellular vesicle-mediated neuron-to-neuron communication

1
1. scibot 19 Jan 2024
  
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  RRID:AB_2534088
  
  DOI: 10.1016/j.celrep.2024.113680
  
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digital.csic.es digital.csic.es

Uso de lipasas libres e inmovilizadas para la hidrólisis y síntesis del bioplástico PLA

2
1. scibot 12 Jan 2024
  
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  RRID:AB_2534088
  
  DOI: 10.7554/eLife.79169
  
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2. scibot 12 Jan 2024
  
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  DOI: 10.7554/eLife.79169
  
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digital.csic.es/handle/10261/51156
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A quantitative model for virus uncoating predicts influenza A infectivity

1
1. scibot 12 Jan 2024
  
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  DOI: 10.1016/j.celrep.2023.113558
  
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Generation of induced pluripotent stem cell line LNDWCHi001-A from a patient with early-onset Parkinson’s disease carrying the homozygous c.1898C > T (p. A633V) mutation in the PLA2G6 gene

1
1. scibot 12 Jan 2024
  
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Multiple reorganizations of the lateral elements of the synaptonemal complex facilitate homolog segregation in Bombyx mori oocytes

1
1. scibot 11 Jan 2024
  
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  RRID:AB_2534088
  
  DOI: 10.1016/j.cub.2023.12.018
  
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Two-Step Actions of Testicular Androgens in the Organization of a Male-Specific Neural Pathway from the Medial Preoptic Area to the Ventral Tegmental Area for Modulating Sexually Motivated Behavior

1
1. scibot 11 Jan 2024
  
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  RRID:AB_2534088
  
  DOI: 10.1523/JNEUROSCI.0361-23.2023
  
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jneurosci.org/content/43/44/7322
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A stapled lipopeptide platform for preventing and treating highly pathogenic viruses of pandemic potential

1
1. scibot 10 Jan 2024
  
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  AB_2534088
  
  DOI: 10.1038/s41467-023-44361-1
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10766962/
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Down-regulating nuclear factor of activated T cells 1 alleviates cognitive deficits in a mouse model of sepsis-associated encephalopathy, possibly by stimulating hippocampal neurogenesis

1
1. scibot 07 Jan 2024
  
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  RRID:AB_2534088
  
  DOI: 10.1016/j.brainres.2023.148731
  
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Generation of three induced pluripotent stem cell lines from individuals with Aicardi-Goutières syndrome caused by a c.3019G>A (p.G1007R) autosomal dominant pathogenic variant in ADAR1

1
1. scibot 07 Jan 2024
  
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  DOI: 10.1016/j.scr.2023.103299
  
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Cytoneme signaling provides essential contributions to mammalian tissue patterning

1
1. scibot 07 Jan 2024
  
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  RRID:AB_2534088
  
  DOI: 10.1016/j.cell.2023.12.003
  
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sciencedirect.com/science/article/pii/S0092867423013338
Dec 2023
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Generation of a TAB2 knockout hESC line (WAe009-A-Z) derived from H9 using CRISPR/Cas9

1
1. scibot 23 Dec 2023
  
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  AB_2534088
  
  DOI: 10.1016/j.scr.2023.103284
  
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Characterization of two human induced pluripotent stem cell lines derived from Batten disease patient fibroblasts harbouring CLN5 mutations

1
1. scibot 23 Dec 2023
  
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  AB_2534088
  
  DOI: 10.1016/j.scr.2023.103291
  
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FANCD2-dependent mitotic DNA synthesis relies on PCNA K164 ubiquitination

1
1. scibot 20 Dec 2023
  
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  RRID:AB_2534088
  
  DOI: 10.1016/j.celrep.2023.113523
  
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Systematic analysis of alternative exon-dependent interactome remodeling reveals multitasking functions of gene regulatory factors

1
1. scibot 17 Dec 2023
  
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  RRID:AB_2534088
  
  DOI: 10.1016/j.molcel.2023.10.034
  
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MORG1 limits mTORC1 signaling by inhibiting Rag GTPases

1
1. scibot 16 Dec 2023
  
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  RRID:AB_2534088
  
  DOI: 10.1016/j.molcel.2023.11.023
  
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Generation of an integration-free induced pluripotent stem cell line, FJMUUHi002-A, from a Rett syndrome patient with a heterozygous mutation p. R133C in MeCP2

1
1. scibot 15 Dec 2023
  
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  RRID:AB_138404
  
  DOI: 10.1016/j.scr.2023.103268
  
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journals.plos.org journals.plos.org

The circadian regulator PER1 promotes cell reprogramming by inhibiting inflammatory signaling from macrophages

1
1. scibot 14 Dec 2023
  
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  RRID:AB_2534088
  
  DOI: 10.1371/journal.pbio.3002419
  
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journals.plos.org/plosbiology/article
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Brain proteome profiling implicates the complement and coagulation cascade in multiple system atrophy brain pathology

1
1. scibot 09 Dec 2023
  
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  RRID:AB_2534088
  
  DOI: 10.1007/s00018-022-04378-z
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9164190/
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Generation and characterization of human induced pluripotent stem cell line METUi002-A from a patient with primary familial brain calcification (PFBC) carrying a heterozygous mutation (c.687dupT (p.Val230CysfsTer28)) in the SLC20A2 gene

1
1. scibot 02 Dec 2023
  
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  RRID:AB_2534088
  
  DOI: 10.1016/j.scr.2023.103226
  
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sciencedirect.com/science/article/pii/S187350612300212X
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Generation of induced pluripotent stem cell lines from a sister pair who suffered post-partum or recurrent Spontaneous Coronary Artery Dissections

1
1. scibot 02 Dec 2023
  
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  RRID:AB_2534088
  
  DOI: 10.1016/j.scr.2023.103238
  
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sciencedirect.com/science/article/pii/S1873506123002246
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YAP targetome reveals activation of SPEM in gastric pre-neoplastic progression and regeneration

1
1. scibot 02 Dec 2023
  
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  RRID:AB_2534088
  
  DOI: 10.1016/j.celrep.2023.113497
  
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IL-18-induced HIF-1α in ILC3s ameliorates the inflammation of C. rodentium-induced colitis

1
1. scibot 02 Dec 2023
  
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  RRID:AB_2534088
  
  DOI: 10.1016/j.celrep.2023.113508
  
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Evaluating signaling bias for synthetic cannabinoid receptor agonists at the cannabinoid CB2 receptor

1
1. scibot 01 Dec 2023
  
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  RRID:AB_2534088
  
  DOI: 10.1002/prp2.1157
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10685394/
www.biorxiv.org www.biorxiv.org

Sleep loss impairs myelin function by altering cholesterol metabolism in oligodendroglia

1
1. scibot 01 Dec 2023
  
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  RRID:AB_2534088
  
  DOI: 10.1101/2023.11.27.568716
  
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biorxiv.org/content/10.1101/2023.11.27.568716v1
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MiR-138-5p Upregulation during Neuronal Maturation Parallels with an Increase in Neuronal Survival

1
1. scibot 01 Dec 2023
  
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  RRID:AB_2534088
  
  DOI: 10.3390/ijms242216509
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10671628/
Nov 2023
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Super-enhancer trapping by the nuclear pore via intrinsically disordered regions of proteins in squamous cell carcinoma cells

1
1. scibot 28 Nov 2023
  
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  RRID:AB_2534088
  
  DOI: 10.1016/j.chembiol.2023.10.005
  
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Functional and spatial proteomics profiling reveals intra- and intercellular signaling crosstalk in colorectal cancer

1
1. scibot 28 Nov 2023
  
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  RRID:AB_2534088
  
  DOI: 10.1016/j.isci.2023.108399
  
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Sbp2l contributes to oligodendrocyte maturation through translational control in Tcf7l2 signaling

1
1. scibot 28 Nov 2023
  
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  RRID:AB_2534088
  
  DOI: 10.1016/j.isci.2023.108451
  
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sciencedirect.com/science/article/pii/S2589004223025282
www.cell.com www.cell.com

Oncogenic signals prime cancer cells for toxic cell overgrowth during a G1 cell cycle arrest

1
1. scibot 28 Nov 2023
  
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  RRID:AB_2534088
  
  DOI: 10.1016/j.molcel.2023.10.020
  
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cell.com/molecular-cell/fulltext/S1097-2765(23)00857-2
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Generation of induced pluripotent stem cell line (TMOi001-A-11) carrying a homozygous deletion in the synemin gene using CRISPR/Cas9

1
1. scibot 28 Nov 2023
  
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  RRID:AB_2534088
  
  DOI: 10.1016/j.scr.2023.103254
  
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Selective inhibition of CDK9 in triple negative breast cancer

1
1. scibot 25 Nov 2023
  
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  RRID:AB_2534088
  
  DOI: 10.1038/s41388-023-02892-3
  
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nature.com/articles/s41388-023-02892-3
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tRNA modification enzyme-dependent redox homeostasis regulates synapse formation and memory

1
1. scibot 18 Nov 2023
  
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  RRID:AB_2534088
  
  DOI: 10.1101/2023.11.14.566895
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10680711/
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SARS-CoV-2 hijacks a cell damage response, which induces transcription of a more efficient Spike S-acyltransferase

1
1. scibot 15 Nov 2023
  
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  RRID:AB_2534088
  
  DOI: 10.1038/s41467-023-43027-2
  
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Prdm12 represses the expression of the visceral neuron determinants Phox2a/b in developing somatosensory ganglia

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1. scibot 10 Nov 2023
  
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  DOI: 10.1016/j.isci.2023.108364
  
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Hepatic palmitoyl-proteomes and acyl-protein thioesterase protein proximity networks link lipid modification and mitochondria

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1. scibot 10 Nov 2023
  
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  DOI: 10.1016/j.celrep.2023.113389
  
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Dopamine error signal to actively cope with lack of expected reward

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1. scibot 09 Nov 2023
  
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  DOI: 10.1126/sciadv.ade5420
  
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  DOI: 10.1126/sciadv.ade5420
  
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Establishment of a human TLR4 compound heterozygous knockout hESC line (WAe009-A-N) to model toll-like receptor 4 deficiency by CRISPR/Cas9 system

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1. scibot 03 Nov 2023
  
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  DOI: 10.1016/j.scr.2023.103225
  
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MFGE-8 identified in fetal mesenchymal-stromal-cell-derived exosomes ameliorates acute hepatic failure pathology

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1. scibot 02 Nov 2023
  
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  DOI: 10.1016/j.isci.2023.108100
  
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Widespread BRCA1/2-independent homologous recombination defects are caused by alterations in RNA-binding proteins

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  DOI: 10.1016/j.xcrm.2023.101255
  
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Transgenic mouse models support a protective role of type I IFN response in SARS-CoV-2 infection-related lung immunopathology and neuroinvasion

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1. scibot 28 Oct 2023
  
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  DOI: 10.1016/j.celrep.2023.113275
  
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β1 integrin signaling governs necroptosis via the chromatin-remodeling factor CHD4

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1. scibot 28 Oct 2023
  
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  DOI: 10.1016/j.celrep.2023.113322
  
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Regulation of STING activity in DNA sensing by ISG15 modification

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1. scibot 27 Oct 2023
  
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  DOI: 10.1016/j.celrep.2023.113277
  
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LINE-1 activation in the cerebellum drives ataxia

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  DOI: 10.1016/j.neuron.2022.08.011
  
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Mapping of multiple neurotransmitter receptor subtypes and distinct protein complexes to the connectome

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1. scibot 14 Oct 2023
  
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  DOI: 10.1101/2023.10.02.560011
  
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Generation and characterization of induced pluripotent stem cells from a Parkinson’s disease patient carrying the digenic LRRK2 p.G2019S and GBA1 p.N409S mutations

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1. scibot 14 Oct 2023
  
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  DOI: 10.1016/j.scr.2023.103212
  
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Dendritic distribution of autophagosomes underlies pathway-selective induction of LTD

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  DOI: 10.1016/j.celrep.2023.112898
  
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Creation of an iPSC-Based Skeletal Muscle Model of McArdle Disease Harbouring the Mutation c.2392T>C (p.Trp798Arg) in the PYGM Gene

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  DOI: 10.3390/biomedicines11092434
  
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Sep 2023
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Palbociclib releases the latent differentiation capacity of neuroblastoma cells

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1. scibot 30 Sep 2023
  
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  DOI: 10.1016/j.devcel.2023.08.028
  
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Principles of assembly and regulation of condensates of Polycomb repressive complex 1 through phase separation

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  DOI: 10.1016/j.celrep.2023.113136
  
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Single-cell epigenome analysis identifies molecular events controlling direct conversion of human fibroblasts to pancreatic ductal-like cells

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1. scibot 30 Sep 2023
  
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  DOI: 10.1016/j.devcel.2023.08.023
  
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