848 Matching Annotations
  1. Last 7 days
  2. www.sciencedirect.com www.sciencedirect.com
    Profound synthetic lethality between SMARCAL1 and FANCM
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    sciencedirect.com/science/article/pii/S1097276524008566
  3. Nov 2024
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    Lysosomal damage triggers a p38 MAPK-dependent phosphorylation cascade to promote lysophagy via the small heat shock protein HSP27
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    sciencedirect.com/science/article/pii/S096098222401457X
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    Systematic screens for fertility genes essential for malaria parasite transmission reveal conserved aspects of sex in a divergent eukaryote
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    sciencedirect.com/science/article/pii/S2405471224003053
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SNARE protein SNAP25 regulates the chloride-transporter KCC2 in neurons
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    pmc.ncbi.nlm.nih.gov/articles/PMC11539599/
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Active RNA synthesis patterns nuclear condensates
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    pmc.ncbi.nlm.nih.gov/articles/PMC11533426/
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    Integrative study of skeletal muscle mitochondrial dysfunction in a murine pancreatic cancer-induced cachexia model
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      DOI: 10.7554/eLife.93312

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    elifesciences.org/articles/93312
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    Striatal cholinergic interneuron pause response requires Kv1 channels, is absent in dyskinetic mice, and is restored by dopamine D5 receptor inverse agonism
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      DOI: 10.7554/eLife.102184.1

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    elifesciences.org/reviewed-preprints/102184
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    Beyond Glycolysis: Aldolase A Is a Novel Effector in Reelin-Mediated Dendritic Development
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    jneurosci.org/content/44/42/e0072242024
  11. www.biorxiv.org www.biorxiv.org
    Synaptic gene expression is coordinated across development by conserved chromatin regulators
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      DOI: 10.1101/2024.10.30.621128

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    biorxiv.org/content/10.1101/2024.10.30.621128v1
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Olanzapine enhances early brain maturation through activation of the NODAL/FOXH1 axis
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  13. Oct 2024
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    Inactive Parp2 causes Tp53-dependent lethal anemia by blocking replication-associated nick ligation in erythroblasts
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    sciencedirect.com/science/article/pii/S1097276524007767
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    PAR2 on oral cancer cells and nociceptors contributes to oral cancer pain that can be relieved by nanoparticle-encapsulated AZ3451
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    sciencedirect.com/science/article/pii/S0142961224004083
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    Rift Valley fever virus coordinates the assembly of a programmable E3 ligase to promote viral replication
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    sciencedirect.com/science/article/pii/S0092867424010262
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    PfSPZ Vaccine induces focused humoral immune response in HIV positive and negative Tanzanian adults
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    sciencedirect.com/science/article/pii/S2352396424004006
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    Pervasive mislocalization of pathogenic coding variants underlying human disorders
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    Antagonistic nanobodies implicate mechanism of GSDMD pore formation and potential therapeutic application
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  20. Sep 2024
  21. onlinelibrary.wiley.com onlinelibrary.wiley.com
    ProSAAS is preferentially up-regulated during homeostatic scaling and reduces amyloid plaque burden in the 5xFAD mouse hippocampus
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      DOI: 10.1111/jnc.16193

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    onlinelibrary.wiley.com/doi/10.1111/jnc.16193
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    Amyloid beta 1-40 and 1-42 fibril ratios and maturation level cause conformational differences with minimal impact on autophagy and cytotoxicity
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      DOI: 10.1111/jnc.16201

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    Katanin regulatory subunit B1 (KATNB1) regulates BTB dynamics through changes in cytoskeletal organization
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  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Segregated basal ganglia output pathways correspond to genetically divergent neuronal subclasses
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    Atypical cellular responses mediated by intracellular constitutive active TrkB (NTRK2) kinase domains and a solely intracellular NTRK2-fusion oncogene
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    Microbiota regulates neonatal disease tolerance to virus-evoked necrotizing enterocolitis by shaping the STAT1-NLRC5 axis in the intestinal epithelium
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      DOI: 10.1016/j.chom.2024.08.013

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    Postsynaptic and Presynaptic NMDARs Have Distinct Roles in Visual Circuit Development
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      DOI: 10.1016/j.celrep.2020.107955

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    Kinetic Heterogeneity of Cancer Cell Fractional Killing
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  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Capture and display of antibodies secreted by hybridoma cells enables fluorescent on-cell screening
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      DOI: 10.1080/19420862.2019.1574520

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  30. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Brain Diffusivity and Structural Changes in the R6/2 Mouse Model of Huntington Disease
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      DOI: 10.1002/jnr.23965

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    Human induced pluripotent stem cell line (FDHSi005-A) derived from a patient with a deep intronic variant in the GNE gene
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    Generation of a fluorescent mNeonGreen insulin reporter line in the H1 (WA01) hESC background
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  33. currentprotocols.onlinelibrary.wiley.com currentprotocols.onlinelibrary.wiley.com
    Reproducible Differentiation of Human Pluripotent Stem Cells into Two-Dimensional Cortical Neuron Cultures with Checkpoints for Success
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  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The function of juvenile–adult transition axis in female sexual receptivity of Drosophila melanogaster
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      DOI: 10.7554/eLife.92545

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    A broadly applicable method for quantifying cardiomyocyte cell division identifies proliferative events following myocardial infarction
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  36. Aug 2024
  37. www.sciencedirect.com www.sciencedirect.com
    MOF-mediated PRDX1 acetylation regulates inflammatory macrophage activation
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    The RNA-binding protein EIF4A3 promotes axon development by direct control of the cytoskeleton
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    sciencedirect.com/science/article/pii/S2211124724010179
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    ALS-FUS mutations cause abnormal PARylation and histone H1.2 interaction, leading to pathological changes
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    sciencedirect.com/science/article/pii/S2211124724009768
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    TGM1/3-mediated transamidation of Exo70 promotes tumor metastasis upon LKB1 inactivation
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    sciencedirect.com/science/article/pii/S2211124724009549
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    Generation of a human induced pluripotent stem cell line ZZUNEUi030-A from a female patient carrying a heterozygous CALM2 (c.395 A > T) mutation
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    sciencedirect.com/science/article/pii/S1873506124002137
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    The divergent effects of G3BP orthologs on human stress granule assembly imply a centric role for the core protein interaction network
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    sciencedirect.com/science/article/pii/S2211124724009677
  43. 52.53.155.43 52.53.155.43
    nemeth-et-al-2024-adiponectin-suppresses-stiffness-dependent-pro-fibrotic-activation-of-lung-fibroblasts-html.html
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    52.53.155.43/b68deb9c62e0885cf46c9d0e6108ed17561f8fea/nemeth-et-al-2024-adiponectin-suppresses-stiffness-dependent-pro-fibrotic-activation-of-lung-fibroblasts-html.html
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    Sugar-mediated non-canonical ubiquitination impairs Nrf1/NFE2L1 activation
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      DOI: 10.1016/j.molcel.2024.07.013

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    Insect-transmitted plant virus balances its vertical transmission through regulating Rab1-mediated receptor localization
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    PMC10174194 S1 Table-html.html
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      DOI: 10.1083/jcb.202211074

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  47. academic.oup.com academic.oup.com
    The adeno-associated virus 2 (AAV2) genome and rep 68/78 proteins interact with cellular sites of DNA damage
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      DOI: 10.1093/hmg/ddab300

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  48. onlinelibrary.wiley.com onlinelibrary.wiley.com
    BDNF‐Gene Transfected Schwann Cell‐Assisted Axonal Extension and Sprouting on New PLA–PPy Microfiber Substrates
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      goat antimouse IgG Alexa Fluor 488

      DOI: 10.1002/mabi.202000391

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    Steroid hormones and human choriogonadotropin influence the distribution of alpha6-integrin and desmoplakin 1 in gland-like endometrial epithelial spheroids
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      Alexa Fluor 488 anti-mouse

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    Spatial patterning of excitatory and inhibitory neuropil territories during spinal circuit development
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      AB_2534088goat

      DOI: 10.1002/cne.24152

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  51. www.nature.com www.nature.com
    Table 2 Antibodies used for different experiments in this report.
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      DOI: 10.1038/s41419-020-2608-8

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    Generating a human induced pluripotent stem cell line (XACHi018-A) from a Timothy syndrome infant carrying heterozygous CACNA1C c.1216G>A (p.G406R) mutation
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  54. Jul 2024
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    Generation of induced pluripotent stem cell line (UCSFi001-A-77) carrying a biallelic frameshift variant in exon 4 of SGIP1 through CRISPR/Cas9
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    Generation of a gene-corrected human isogenic iPSC line from an Alzheimer’s disease iPSC line carrying the PSEN1 H163R mutation
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    Generation of an induced pluripotent stem cell line (BIORTCi001-A) from a healthy adult indigenous Nigerian participant
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      DOI: 10.1016/j.scr.2024.103503

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  58. www.cell.com www.cell.com
    Ceramide-induced cleavage of GPR64 intracellular domain drives Ewing sarcoma
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    cell.com/cell-reports/fulltext/S2211-1247(24)00826-X
  59. www.cell.com www.cell.com
    The splicing factor CCAR1 regulates the Fanconi anemia/BRCA pathway
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      DOI: 10.1016/j.molcel.2024.06.031

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    cell.com/molecular-cell/fulltext/S1097-2765(24)00538-0
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Differences in male Aedes aegypti and Aedes albopictus hearing systems facilitate recognition of conspecific female flight tones
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      DOI: 10.1016/j.isci.2024.110264

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    Establishment of an induced pluripotent stem cell line from a patient with X-linked Alport syndrome carrying a hemizygous splicing variant (NM_033380; c.929[exon 16]delG) in the collagen type IV alpha 5 chain gene
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    Microglial-derived C1q integrates into neuronal ribonucleoprotein complexes and impacts protein homeostasis in the aging brain
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      DOI: 10.1016/j.cell.2024.05.058

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  63. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  64. www.biorxiv.org www.biorxiv.org
    Single-cell transcriptomics predict novel potential regulators of acute epithelial restitution in the ischemia-injured intestine
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      DOI: 10.1101/2024.06.28.601271

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  65. www.sciencedirect.com www.sciencedirect.com
    Tissue Mechanics Regulate Mitotic Nuclear Dynamics during Epithelial Development
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      DOI: 10.1016/j.cub.2020.04.041

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  66. www.nature.com www.nature.com
    Ube3a unsilencer for the potential treatment of Angelman syndrome
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  67. Jun 2024
  68. www.sciencedirect.com www.sciencedirect.com
    H19 influenza A virus exhibits species-specific MHC class II receptor usage
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    EYA protein complex is required for Wntless retrograde trafficking from endosomes to Golgi
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  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sonic Hedgehog activates prostaglandin signaling to stabilize primary cilium length
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      DOI: 10.1083/jcb.202306002

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  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Human SIRT5 variants with reduced stability and activity do not cause neuropathology in mice
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  72. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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      D. Secondary antibodies used for immunoblotting or confocal imaging.Figure S4Figure S4. The selected pS129 antibodies recognize all specifically pS129-aSyn but notunmodified aSyn (related to Figure 2)A. Forty nanograms of human recombinant monomeric aSyn unphosphorylated (WT) or phosphorylatedat the S129 residue (pS129) were detected by WB using commercial antibodies (pSyn#64, MJF-R13,81a, EP1536Y and GTX) or the LASH-EGT homemade pS129 antibody (respective epitopes listed inFigure S3) combined with total aSyn antibodies (Fl-140 or SYN-1).B-C. Forty nanograms of human recombinant monomeric aSyn (WT) or phosphorylated at the Y39(pY39) or S87 (pS87) or S129 residues (pS129) and WB was performed using the pY39 antibody (B)

      DOI: 10.1101/2022.03.30.486322

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    Neuronal activity-driven O-GlcNAcylation promotes mitochondrial plasticity
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    Viral infection disrupts intestinal homeostasis via Sting-dependent NF-κB signaling in Drosophila
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  76. May 2024
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    Axonal endoplasmic reticulum tubules control local translation via P180/RRBP1-mediated ribosome interactions
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    Insights from multi-omic modeling of neurodegeneration in xeroderma pigmentosum using an induced pluripotent stem cell system
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    The Neurog2-Tbr2 axis forms a continuous transition to the neurogenic gene expression state in neural stem cells
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    Nuclear aggregates of NONO/SFPQ and A-to-I-edited RNA in Parkinson’s disease and dementia with Lewy bodies
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    Generation of induced pluripotent stem cell lines from two unrelated patients affected by intellectual disability carrying homozygous variants in SGIP1
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    Adult-Onset Deletion of ATP13A2 in Mice Induces Progressive Nigrostriatal Pathway Dopaminergic Degeneration and Lysosomal Abnormalities
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    NRP1 is a receptor for mammalian orthoreovirus engaged by distinct capsid subunits
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  84. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PDZD8 promotes autophagy at ER-Lysosome contact sites to regulate synaptogenesis
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    ProSAAS is Preferentially Secreted from Neurons During Homeostatic Scaling and Reduces Amyloid Plaque Size in the 5xFAD Mouse Hippocampus
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    Cox7a1 controls skeletal muscle physiology and heart regeneration through complex IV dimerization
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  87. www.sciencedirect.com www.sciencedirect.com
    The thalamic reticular nucleus orchestrates social memory
    1
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  89. www.sciencedirect.com www.sciencedirect.com
    ER-associated degradation adapter Sel1L is required for CD8+ T cell function and memory formation following acute viral infection
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      DOI: 10.1016/j.celrep.2024.114156

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  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Detection of ER Stress in iPSC-Derived Neurons Carrying the p.N370S Mutation in the GBA1 Gene
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      DOI: 10.3390/biomedicines12040744

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  91. www.sciencedirect.com www.sciencedirect.com
    Generation and characterization of six human induced pluripotent stem cell lines (hiPSCs) from three individuals with SSADH Deficiency and CRISPR-corrected isogenic controls
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    Efficient generation of induced pluripotent stem cell lines from healthy donors’ peripheral blood mononuclear cells of different genders
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  93. www.nature.com www.nature.com
    Reprogramming fibroblast into human iBlastoids
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      DOI: 10.1038/s41596-024-00984-2

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  94. www.sciencedirect.com www.sciencedirect.com
    Accumulation of APP C-terminal fragments causes endolysosomal dysfunction through the dysregulation of late endosome to lysosome-ER contact sites
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    Time-series reconstruction of the molecular architecture of human centriole assembly
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  96. 52.53.155.43 52.53.155.43
    Sustained type I interferon signaling after human immunodeficiency virus type 1 infection of human iPSC derived microglia and cerebral organoids
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  97. www.sciencedirect.com www.sciencedirect.com
    Truncating NFKB1 variants cause combined NLRP3 inflammasome activation and type I interferon signaling and predispose to necrotizing fasciitis
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  98. link.springer.com link.springer.com
    Map-1a regulates Sertoli cell BTB dynamics through the cytoskeletal organization of microtubule and F-actin
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  99. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Statins inhibit protein kinase D (PKD) activation in intestinal cells and prevent PKD1-induced growth of murine enteroids
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  100. Mar 2024
  101. www.sciencedirect.com www.sciencedirect.com
    Interaction between host G3BP and viral nucleocapsid protein regulates SARS-CoV-2 replication and pathogenicity
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  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Piezo1 mechanosensing regulates integrin-dependent chemotactic migration in human T cells
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    JAK-STAT pathway activation compromises nephrocyte function in a Drosophila high-fat diet model of chronic kidney disease
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    A surge in cytoplasmic viscosity triggers nuclear remodeling required for Dux silencing and pre-implantation embryo development
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    Disease-causing Slack potassium channel mutations produce opposite effects on excitability of excitatory and inhibitory neurons
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    Age-related ciliopathy: Obesogenic shortening of melanocortin-4 receptor-bearing neuronal primary cilia
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    Securin acetylation prevents precocious separase activation and premature sister chromatid separation
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    Generation of induced pluripotent stem cells (UCLi024-A) from a patient with argininosuccinate lyase deficiency carrying a homozygous c.437G > A (p.Arg146Gln) mutation
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    The GATOR2 complex maintains lysosomal-autophagic function by inhibiting the protein degradation of MiT/TFEs
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  110. Feb 2024
  111. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    KIF3A tail domain phosphorylation is not required for ciliogenesis in mouse embryonic fibroblasts
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    Canonical Wnt signaling directs the generation of functional human PSC-derived atrioventricular canal cardiomyocytes in bioprinted cardiac tissues
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    Generation of IPi001-A/B/C human induced pluripotent stem cell lines from healthy amniotic fluid cells
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    Generation of a TMEM43 knockout human induced pluripotent stem cell line (HDZi003-A-1) using CRISPR/Cas9
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    Adhesion-clutch between DCC and netrin-1 mediates netrin-1–induced axonal haptotaxis
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  116. 52.53.155.43 52.53.155.43
    The iron chelator and OXPHOS inhibitor VLX600 induces mitophagy and an autophagy-dependent type of cell death in glioblastoma cells
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  117. www.sciencedirect.com www.sciencedirect.com
    Complex formation of immunoglobulin superfamily molecules Side-IV and Beat-IIb regulates synaptic specificity
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    Establishment of an induced pluripotent stem cell line from a Noonan syndrome patient with the heterozygote mutation p.S257L (c.770C>T) in RAF1 gene
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  119. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Metabolic rewiring and autophagy inhibition correct lysosomal storage disease in Mucopolysaccharidosis IIIB
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  120. journals.physiology.org journals.physiology.org
    The iron chelator and OXPHOS inhibitor VLX600 induces mitophagy and an autophagy-dependent type of cell death in glioblastoma cells
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    RNF4 prevents genomic instability caused by chronic DNA under-replication
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  122. www.biorxiv.org www.biorxiv.org
    Mechanical Netrin-1-DCC Coupling Mediates Netrin-1–induced Axonal Haptotaxis
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  123. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genetic background variation impacts microglial heterogeneity and disease progression in amyotrophic lateral sclerosis model mice
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  124. genomebiology.biomedcentral.com genomebiology.biomedcentral.com
    The androgen receptor interacts with GATA3 to transcriptionally regulate a luminal epithelial cell phenotype in breast cancer
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      DOI: 10.1186/s13059-023-03161-y

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  125. www.sciencedirect.com www.sciencedirect.com
    Generation of the human induced pluripotent stem cell line PUMCi005-A from a patient with Perrault syndrome
    1
    1. scibot 02 Feb 2024
      RRID: AB138404

      DOI: 10.1016/j.scr.2024.103318

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  126. www.sciencedirect.com www.sciencedirect.com
    Dual roles of CCDC102A in governing centrosome duplication and cohesion
    1
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      DOI: 10.1016/j.celrep.2024.113696

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  127. www.sciencedirect.com www.sciencedirect.com
    Evolution of human H3N2 influenza virus receptor specificity has substantially expanded the receptor-binding domain site
    2
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      RRID:AB_138404

      DOI: 10.1016/j.chom.2024.01.003

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      RRID:AB_138404

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    sciencedirect.com/science/article/pii/S1931312824000076
  128. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An enriched environment ameliorates the reduction of parvalbumin-positive interneurons in the medial prefrontal cortex caused by maternal separation early in life
    1
    1. scibot 01 Feb 2024
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      DOI: 10.3389/fnins.2023.1308368

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    ncbi.nlm.nih.gov/pmc/articles/PMC10825025/
  129. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Characterization of a novel variant in the HR1 domain of MFN2 in a patient with ataxia, optic atrophy and sensorineural hearing loss
    1
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      RRID:AB_138404

      DOI: 10.12688/f1000research.53230.2

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  130. Jan 2024
  131. www.sciencedirect.com www.sciencedirect.com
    Mapping of multiple neurotransmitter receptor subtypes and distinct protein complexes to the connectome
    2
    1. scibot 23 Jan 2024
      RRID: AB_2534088

      DOI: 10.1016/j.neuron.2023.12.014

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      DOI: 10.1016/j.neuron.2023.12.014

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  132. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Notch receptor-ligand binding facilitates extracellular vesicle-mediated neuron-to-neuron communication
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  133. digital.csic.es digital.csic.es
    Uso de lipasas libres e inmovilizadas para la hidrólisis y síntesis del bioplástico PLA
    2
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      RRID:AB_2534088

      DOI: 10.7554/eLife.79169

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      DOI: 10.7554/eLife.79169

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    digital.csic.es/handle/10261/51156
  134. www.sciencedirect.com www.sciencedirect.com
    A quantitative model for virus uncoating predicts influenza A infectivity
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    sciencedirect.com/science/article/pii/S221112472301570X
  135. www.sciencedirect.com www.sciencedirect.com
    Generation of induced pluripotent stem cell line LNDWCHi001-A from a patient with early-onset Parkinson’s disease carrying the homozygous c.1898C > T (p. A633V) mutation in the PLA2G6 gene
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    1. scibot 12 Jan 2024
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    sciencedirect.com/science/article/pii/S1873506124000035
  136. www.sciencedirect.com www.sciencedirect.com
    Multiple reorganizations of the lateral elements of the synaptonemal complex facilitate homolog segregation in Bombyx mori oocytes
    1
    1. scibot 11 Jan 2024
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      DOI: 10.1016/j.cub.2023.12.018

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  137. www.jneurosci.org www.jneurosci.org
    Two-Step Actions of Testicular Androgens in the Organization of a Male-Specific Neural Pathway from the Medial Preoptic Area to the Ventral Tegmental Area for Modulating Sexually Motivated Behavior
    1
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      RRID:AB_2534088

      DOI: 10.1523/JNEUROSCI.0361-23.2023

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    jneurosci.org/content/43/44/7322
  138. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A stapled lipopeptide platform for preventing and treating highly pathogenic viruses of pandemic potential
    1
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      AB_2534088

      DOI: 10.1038/s41467-023-44361-1

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    ncbi.nlm.nih.gov/pmc/articles/PMC10766962/
  139. www.sciencedirect.com www.sciencedirect.com
    Down-regulating nuclear factor of activated T cells 1 alleviates cognitive deficits in a mouse model of sepsis-associated encephalopathy, possibly by stimulating hippocampal neurogenesis
    1
    1. scibot 07 Jan 2024
      RRID:AB_2534088

      DOI: 10.1016/j.brainres.2023.148731

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    sciencedirect.com/science/article/pii/S0006899323005024
  140. www.sciencedirect.com www.sciencedirect.com
    Generation of three induced pluripotent stem cell lines from individuals with Aicardi-Goutières syndrome caused by a c.3019G>A (p.G1007R) autosomal dominant pathogenic variant in ADAR1
    1
    1. scibot 07 Jan 2024
      RRID:AB_2534088

      DOI: 10.1016/j.scr.2023.103299

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  141. www.sciencedirect.com www.sciencedirect.com
    Cytoneme signaling provides essential contributions to mammalian tissue patterning
    1
    1. scibot 07 Jan 2024
      RRID:AB_2534088

      DOI: 10.1016/j.cell.2023.12.003

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    sciencedirect.com/science/article/pii/S0092867423013338
  142. Dec 2023
  143. www.sciencedirect.com www.sciencedirect.com
    Generation of a TAB2 knockout hESC line (WAe009-A-Z) derived from H9 using CRISPR/Cas9
    1
    1. scibot 23 Dec 2023
      AB_2534088

      DOI: 10.1016/j.scr.2023.103284

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    sciencedirect.com/science/article/pii/S1873506123002702
  144. www.sciencedirect.com www.sciencedirect.com
    Characterization of two human induced pluripotent stem cell lines derived from Batten disease patient fibroblasts harbouring CLN5 mutations
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    1. scibot 23 Dec 2023
      AB_2534088

      DOI: 10.1016/j.scr.2023.103291

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    sciencedirect.com/science/article/pii/S1873506123002775
  145. www.sciencedirect.com www.sciencedirect.com
    FANCD2-dependent mitotic DNA synthesis relies on PCNA K164 ubiquitination
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    1. scibot 20 Dec 2023
      RRID:AB_2534088

      DOI: 10.1016/j.celrep.2023.113523

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    sciencedirect.com/science/article/pii/S2211124723015358
  146. www.sciencedirect.com www.sciencedirect.com
    Systematic analysis of alternative exon-dependent interactome remodeling reveals multitasking functions of gene regulatory factors
    1
    1. scibot 17 Dec 2023
      RRID:AB_2534088

      DOI: 10.1016/j.molcel.2023.10.034

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  147. www.sciencedirect.com www.sciencedirect.com
    MORG1 limits mTORC1 signaling by inhibiting Rag GTPases
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      DOI: 10.1016/j.molcel.2023.11.023

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    sciencedirect.com/science/article/pii/S1097276523009681
  148. www.sciencedirect.com www.sciencedirect.com
    Generation of an integration-free induced pluripotent stem cell line, FJMUUHi002-A, from a Rett syndrome patient with a heterozygous mutation p. R133C in MeCP2
    1
    1. scibot 15 Dec 2023
      RRID:AB_138404

      DOI: 10.1016/j.scr.2023.103268

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  149. journals.plos.org journals.plos.org
    The circadian regulator PER1 promotes cell reprogramming by inhibiting inflammatory signaling from macrophages
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      DOI: 10.1371/journal.pbio.3002419

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  150. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Brain proteome profiling implicates the complement and coagulation cascade in multiple system atrophy brain pathology
    1
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      DOI: 10.1007/s00018-022-04378-z

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  151. www.sciencedirect.com www.sciencedirect.com
    Generation and characterization of human induced pluripotent stem cell line METUi002-A from a patient with primary familial brain calcification (PFBC) carrying a heterozygous mutation (c.687dupT (p.Val230CysfsTer28)) in the SLC20A2 gene
    1
    1. scibot 02 Dec 2023
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  152. www.sciencedirect.com www.sciencedirect.com
    Generation of induced pluripotent stem cell lines from a sister pair who suffered post-partum or recurrent Spontaneous Coronary Artery Dissections
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    1. scibot 02 Dec 2023
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      DOI: 10.1016/j.scr.2023.103238

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    sciencedirect.com/science/article/pii/S1873506123002246
  153. www.sciencedirect.com www.sciencedirect.com
    YAP targetome reveals activation of SPEM in gastric pre-neoplastic progression and regeneration
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      DOI: 10.1016/j.celrep.2023.113497

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  154. www.sciencedirect.com www.sciencedirect.com
    IL-18-induced HIF-1α in ILC3s ameliorates the inflammation of C. rodentium-induced colitis
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  155. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Evaluating signaling bias for synthetic cannabinoid receptor agonists at the cannabinoid CB2 receptor
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  156. www.biorxiv.org www.biorxiv.org
    Sleep loss impairs myelin function by altering cholesterol metabolism in oligodendroglia
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      DOI: 10.1101/2023.11.27.568716

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    biorxiv.org/content/10.1101/2023.11.27.568716v1
  157. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MiR-138-5p Upregulation during Neuronal Maturation Parallels with an Increase in Neuronal Survival
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      DOI: 10.3390/ijms242216509

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  158. Nov 2023
  159. www.sciencedirect.com www.sciencedirect.com
    Super-enhancer trapping by the nuclear pore via intrinsically disordered regions of proteins in squamous cell carcinoma cells
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    1. scibot 28 Nov 2023
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      DOI: 10.1016/j.chembiol.2023.10.005

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  160. www.sciencedirect.com www.sciencedirect.com
    Functional and spatial proteomics profiling reveals intra- and intercellular signaling crosstalk in colorectal cancer
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      DOI: 10.1016/j.isci.2023.108399

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  161. www.sciencedirect.com www.sciencedirect.com
    Sbp2l contributes to oligodendrocyte maturation through translational control in Tcf7l2 signaling
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      DOI: 10.1016/j.isci.2023.108451

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  162. www.cell.com www.cell.com
    Oncogenic signals prime cancer cells for toxic cell overgrowth during a G1 cell cycle arrest
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      DOI: 10.1016/j.molcel.2023.10.020

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    cell.com/molecular-cell/fulltext/S1097-2765(23)00857-2
  163. www.sciencedirect.com www.sciencedirect.com
    Generation of induced pluripotent stem cell line (TMOi001-A-11) carrying a homozygous deletion in the synemin gene using CRISPR/Cas9
    1
    1. scibot 28 Nov 2023
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      DOI: 10.1016/j.scr.2023.103254

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  164. www.nature.com www.nature.com
    Selective inhibition of CDK9 in triple negative breast cancer
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    1. scibot 25 Nov 2023
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      DOI: 10.1038/s41388-023-02892-3

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    nature.com/articles/s41388-023-02892-3
  165. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    tRNA modification enzyme-dependent redox homeostasis regulates synapse formation and memory
    1
    1. scibot 18 Nov 2023
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      DOI: 10.1101/2023.11.14.566895

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    ncbi.nlm.nih.gov/pmc/articles/PMC10680711/
  166. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SARS-CoV-2 hijacks a cell damage response, which induces transcription of a more efficient Spike S-acyltransferase
    1
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      DOI: 10.1038/s41467-023-43027-2

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    ncbi.nlm.nih.gov/pmc/articles/PMC10640587/
  167. www.sciencedirect.com www.sciencedirect.com
    Prdm12 represses the expression of the visceral neuron determinants Phox2a/b in developing somatosensory ganglia
    1
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      DOI: 10.1016/j.isci.2023.108364

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    sciencedirect.com/science/article/pii/S2589004223024410
  168. www.sciencedirect.com www.sciencedirect.com
    Hepatic palmitoyl-proteomes and acyl-protein thioesterase protein proximity networks link lipid modification and mitochondria
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      DOI: 10.1016/j.celrep.2023.113389

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  169. www.science.org www.science.org
    Dopamine error signal to actively cope with lack of expected reward
    2
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      DOI: 10.1126/sciadv.ade5420

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  170. www.sciencedirect.com www.sciencedirect.com
    Establishment of a human TLR4 compound heterozygous knockout hESC line (WAe009-A-N) to model toll-like receptor 4 deficiency by CRISPR/Cas9 system
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    sciencedirect.com/science/article/pii/S1873506123002118
  171. www.sciencedirect.com www.sciencedirect.com
    MFGE-8 identified in fetal mesenchymal-stromal-cell-derived exosomes ameliorates acute hepatic failure pathology
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    sciencedirect.com/science/article/pii/S2589004223021776
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    Widespread BRCA1/2-independent homologous recombination defects are caused by alterations in RNA-binding proteins
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      DOI: 10.1016/j.xcrm.2023.101255

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    sciencedirect.com/science/article/pii/S2666379123004329
  173. Oct 2023
  174. www.sciencedirect.com www.sciencedirect.com
    Transgenic mouse models support a protective role of type I IFN response in SARS-CoV-2 infection-related lung immunopathology and neuroinvasion
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    sciencedirect.com/science/article/pii/S2211124723012871
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    β1 integrin signaling governs necroptosis via the chromatin-remodeling factor CHD4
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      DOI: 10.1016/j.celrep.2023.113322

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    Regulation of STING activity in DNA sensing by ISG15 modification
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  177. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    LINE-1 activation in the cerebellum drives ataxia
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      DOI: 10.1016/j.neuron.2022.08.011

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  178. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mapping of multiple neurotransmitter receptor subtypes and distinct protein complexes to the connectome
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      DOI: 10.1101/2023.10.02.560011

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    Generation and characterization of induced pluripotent stem cells from a Parkinson’s disease patient carrying the digenic LRRK2 p.G2019S and GBA1 p.N409S mutations
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  180. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dendritic distribution of autophagosomes underlies pathway-selective induction of LTD
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  181. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Creation of an iPSC-Based Skeletal Muscle Model of McArdle Disease Harbouring the Mutation c.2392T>C (p.Trp798Arg) in the PYGM Gene
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  182. Sep 2023
  183. www.sciencedirect.com www.sciencedirect.com
    Palbociclib releases the latent differentiation capacity of neuroblastoma cells
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    Principles of assembly and regulation of condensates of Polycomb repressive complex 1 through phase separation
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    Single-cell epigenome analysis identifies molecular events controlling direct conversion of human fibroblasts to pancreatic ductal-like cells
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      DOI: 10.1016/j.devcel.2023.08.023

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    Identifying G protein-coupled receptors involved in adipose tissue function using the innovative RNA-seq database FATTLAS
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      DOI: 10.1016/j.isci.2023.107841

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  187. journals.physiology.org journals.physiology.org
    G-protein tonic inhibition of calcium channels in pancreatic β-cells
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    Damaged mitochondria recruit the effector NEMO to activate NF-κB signaling
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  189. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Sialic acid biosynthesis pathway blockade disturbs neuronal network formation in human iPSC-derived excitatory neurons
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      DOI: 10.1111/jnc.15934

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  190. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SOD1G93A Astrocyte-Derived Extracellular Vesicles Induce Motor Neuron Death by a miRNA-155-5p-Mediated Mechanism
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      DOI: 10.1177/17590914231197527

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    ncbi.nlm.nih.gov/pmc/articles/PMC10467309/
  191. Aug 2023
  192. www.sciencedirect.com www.sciencedirect.com
    Generation of the human iPSC lines AKOSi011-A carrying the mutation p.Pro65Ser/p.Asp35T and AKOSi012-A, carrying the mutation p.Tyr231His, derived from FAHN patient fibroblasts
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    sciencedirect.com/science/article/pii/S1873506123001642
  193. www.sciencedirect.com www.sciencedirect.com
    Mouse embryonic stem cells embody organismal-level cold resistance
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    Mesenchymal stem cell-derived rapid drug screening system for Alzheimer's disease for the identification of novel drugs
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    Multifaceted contributions of Dicer2 to arbovirus transmission by Aedes aegypti
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    ArfGAP1 regulates the endosomal sorting of guidance receptors to promote directed collective cell migration in vivo
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    Low-oxygen tension augments chondrocyte sensitivity to biomimetic thermomechanical cues in cartilage-engineered constructs
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    Optimized protocol for the generation of functional human induced-pluripotent-stem-cell-derived dopaminergic neurons
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    Senescent cells form nuclear foci that contain the 26S proteasome
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  200. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Cooperative and competitive regulation of the astrocytic transcriptome by neurons and endothelial cells: Impact on astrocyte maturation
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  201. Jul 2023
  202. www.sciencedirect.com www.sciencedirect.com
    Identification of IQCH as a calmodulin-associated protein required for sperm motility in humans
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    Aurora A polyubiquitinates the BRCA1-interacting protein OLA1 to promote centrosome maturation
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    Sox10 escalates vascular inflammation by mediating vascular smooth muscle cell transdifferentiation and pyroptosis in neointimal hyperplasia
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    Phosphoribosyl-linked serine ubiquitination of USP14 by the SidE family effectors of Legionella excludes p62 from the bacterial phagosome
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      DOI: 10.1016/j.celrep.2023.112817

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    Genome-scale mapping of DNA damage suppressors through phenotypic CRISPR-Cas9 screens
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    Reduced histone gene copy number disrupts Drosophila Polycomb function
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      DOI: 10.1093/genetics/iyad106

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      Curator: @scibot

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  208. www.nature.com www.nature.com
    Inhibition of AXL receptor tyrosine kinase enhances brown adipose tissue functionality in mice
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    1. scibot 15 Jul 2023
      RRID:AB_2534088

      DOI: 10.1038/s41467-023-39715-8

      Resource: (Thermo Fisher Scientific Cat# A-11029, RRID:AB_2534088)

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