362 Matching Annotations
  1. May 2021
  2. www.sciencedirect.com www.sciencedirect.com
    PIWI proteomics identifies Atari and Pasilla as piRNA biogenesis factors in Aedes mosquitoes
    1
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    sciencedirect.com/science/article/pii/S2211124721004046
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    Ligand Binding to the Collagen VI Receptor Triggers a Talin-to-RhoA Switch that Regulates Receptor Endocytosis
    1
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    sciencedirect.com/science/article/pii/S1534580720303178
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    Comprehensive Analysis of G1 Cyclin Docking Motif Sequences that Control CDK Regulatory Potency In Vivo
    1
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      DOI: 10.1016/j.cub.2020.08.099

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    sciencedirect.com/science/article/pii/S0960982220312896
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    Toll receptors remodel epithelia by directing planar-polarized Src and PI3K activity
    1
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    sciencedirect.com/science/article/pii/S153458072100321X
  6. Apr 2021
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Functional interpretation of ATAD3A variants in neuro-mitochondrial phenotypes
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC8042885/
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    Integrated genomic analysis reveals key features of long undecoded transcript isoform-based gene repression
    1
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    sciencedirect.com/science/article/pii/S1097276521001817
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    Epigenomic tensor predicts disease subtypes and reveals constrained tumor evolution
    1
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    sciencedirect.com/science/article/pii/S2211124721002412
  10. Mar 2021
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    Modeling the complete kinetics of coxsackievirus B3 reveals human determinants of host-cell feedback
    1
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    sciencedirect.com/science/article/pii/S2405471221000788
  12. www.embopress.org www.embopress.org
    CA10 regulates neurexin heparan sulfate addition via a direct binding in the secretory pathway
    1
    1. scibot 03 Mar 2021
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      DOI: 10.15252/embr.202051349

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    embopress.org/doi/abs/10.15252/embr.202051349
  13. Feb 2021
  14. www.sciencedirect.com www.sciencedirect.com
    Reticulon-3 Promotes Endosome Maturation at ER Membrane Contact Sites
    1
    1. scibot 28 Feb 2021
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    sciencedirect.com/science/article/pii/S1534580720310200
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    Structural Basis of WLS/Evi-Mediated Wnt Transport and Secretion
    1
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    sciencedirect.com/science/article/pii/S009286742031610X
  16. www.cell.com www.cell.com
    Fatal Perinatal Mitochondrial Cardiac Failure Caused by Recurrent De Novo Duplications in the ATAD3 Locus
    1
    1. scibot 26 Feb 2021
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    cell.com/med/fulltext/S2666-6340(20)30009-X
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitochondrial Membrane Potential Regulates Nuclear Gene Expression in Macrophages Exposed to Prostaglandin E2
    1
    1. scibot 25 Feb 2021
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      DOI: 10.1016/j.immuni.2018.10.011

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    ncbi.nlm.nih.gov/pmc/articles/PMC7271981/
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Whole brain delivery of an instability-prone Mecp2 transgene improves behavioral and molecular pathological defects in mouse models of Rett syndrome
    1
    1. scibot 25 Feb 2021
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      DOI: 10.7554/eLife.52629

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    ncbi.nlm.nih.gov/pmc/articles/PMC7117907/
  19. www.cell.com www.cell.com
    Expanded Coverage of the 26S Proteasome Conformational Landscape Reveals Mechanisms of Peptidase Gating
    1
    1. scibot 25 Feb 2021
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      DOI: 10.1016/j.celrep.2018.07.004

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    cell.com/cell-reports/abstract/S2211-1247(18)31081-7
  20. www.cell.com www.cell.com
    Regulation of S100A8 Stability by RNF5 in Intestinal Epithelial Cells Determines Intestinal Inflammation and Severity of Colitis
    1
    1. scibot 25 Feb 2021
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      DOI: 10.1016/j.celrep.2018.08.057

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    cell.com/cell-reports/abstract/S2211-1247(18)31344-5
  21. Jan 2021
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cross-compartment signal propagation in the mitotic exit network
    1
    1. scibot 28 Jan 2021
      RRID:AB_255656

      DOI: 10.7554/eLife.63645

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    ncbi.nlm.nih.gov/pmc/articles/PMC7822594/
  23. academic.oup.com academic.oup.com
    Two cases of anti-PIT-1 hypophysitis exhibited as a form of paraneoplastic syndrome not associated with thymoma
    1
    1. scibot 26 Jan 2021
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      DOI: 10.1210/jendso/bvaa194

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    academic.oup.com/jes/article/5/3/bvaa194/6056675
  24. www.sciencedirect.com www.sciencedirect.com
    Transcription levels of a noncoding RNA orchestrate opposing regulatory and cell fate outcomes in yeast
    1
    1. scibot 20 Jan 2021
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      DOI: 10.1016/j.celrep.2020.108643

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    sciencedirect.com/science/article/pii/S2211124720316326
  25. Dec 2020
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sequential activation of transcriptional repressors promotes progenitor commitment by silencing stem cell identity genes
    1
    1. scibot 16 Dec 2020
      RRID:AB_2556564

      DOI: 10.7554/eLife.56187

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    ncbi.nlm.nih.gov/pmc/articles/PMC7728440/
  27. www.sciencedirect.com www.sciencedirect.com
    Human VAPome Analysis Reveals MOSPD1 and MOSPD3 as Membrane Contact Site Proteins Interacting with FFAT-Related FFNT Motifs
    1
    1. scibot 13 Dec 2020
      RRID:AB_2556564

      DOI: 10.1016/j.celrep.2020.108475

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    sciencedirect.com/science/article/pii/S2211124720314649
  28. www.cell.com www.cell.com
    Spatiotemporal Proteomic Analysis of Stress Granule Disassembly Using APEX Reveals Regulation by SUMOylation and Links to ALS Pathogenesis
    1
    1. scibot 10 Dec 2020
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      DOI: 10.1016/j.molcel.2020.10.032

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    cell.com/molecular-cell/fulltext/S1097-2765(20)30739-5
  29. link.springer.com link.springer.com
    Proximity-based proteomics reveals the thylakoid lumen proteome in the cyanobacterium Synechococcus sp. PCC 7002
    1
    1. scibot 08 Dec 2020
      streptavidin-HRP

      DOI: 10.1007/s11120-020-00806-y

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    link.springer.com/article/10.1007/s11120-020-00806-y
  30. Nov 2020
  31. www.sciencedirect.com www.sciencedirect.com
    CK2 Inhibits TIMELESS Nuclear Export and Modulates CLOCK Transcriptional Activity to Regulate Circadian Rhythms
    1
    1. scibot 28 Nov 2020
      Mouse monoclonal anti-V5

      DOI: 10.1016/j.cub.2020.10.061

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    sciencedirect.com/science/article/pii/S0960982220316043
  32. www.cell.com www.cell.com
    A Neural Basis for Categorizing Sensory Stimuli to Enhance Decision Accuracy
    1
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      DOI: 10.1016/j.cub.2020.09.045

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    cell.com/current-biology/abstract/S0960-9822(20)31415-9
  33. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    isoTarget: A Genetic Method for Analyzing the Functional Diversity of Splicing Isoforms In Vivo
    1
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      DOI: 10.1016/j.celrep.2020.108361

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    pubmed.ncbi.nlm.nih.gov/33176150/
  34. www.nature.com www.nature.com
    Proximity labeling in mammalian cells with TurboID and split-TurboID
    1
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      DOI: 10.1038/s41596-020-0399-0

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    nature.com/articles/s41596-020-0399-0
  35. www.sciencedirect.com www.sciencedirect.com
    Metabolic Reprogramming Induces Germinal Center B Cell Differentiation through Bcl6 Locus Remodeling
    1
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      DOI: 10.1016/j.celrep.2020.108333

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    sciencedirect.com/science/article/pii/S221112472031322X
  36. www.sciencedirect.com www.sciencedirect.com
    Comparative Connectomics Reveals How Partner Identity, Location, and Activity Specify Synaptic Connectivity in Drosophila
    1
    1. scibot 03 Nov 2020
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      DOI: 10.1016/j.neuron.2020.10.004

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    sciencedirect.com/science/article/pii/S0896627320307728
  37. Oct 2020
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sperm-specific COX6B2 enhances oxidative phosphorylation, proliferation, and survival in human lung adenocarcinoma
    1
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      DOI: 10.7554/eLife.58108

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    ncbi.nlm.nih.gov/pmc/articles/PMC7556868/
  39. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    A Comprehensive Subcellular Atlas of the Toxoplasma Proteome via hyperLOPIT Provides Spatial Context for Protein Functions
    1
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      DOI: 10.1016/j.chom.2020.09.011

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    pubmed.ncbi.nlm.nih.gov/33053376/
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR-Csy4-Mediated Editing of Rotavirus Double-Stranded RNA Genome
    1
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      DOI: 10.1016/j.celrep.2020.108205

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    ncbi.nlm.nih.gov/pmc/articles/PMC7523552/
  41. Sep 2020
  42. www.sciencedirect.com www.sciencedirect.com
    A Thalamic Orphan Receptor Drives Variability in Short-Term Memory
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      DOI: 10.1016/j.cell.2020.09.011

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    sciencedirect.com/science/article/pii/S0092867420311521
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR-Csy4-Mediated Editing of Rotavirus Double-Stranded RNA Genome
    1
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  44. www.sciencedirect.com www.sciencedirect.com
    Telomerase Repairs Collapsed Replication Forks at Telomeres
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    sciencedirect.com/science/article/pii/S2211124720302333
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ingestion of Food Particles Regulates the Mechanosensing Misshapen-Yorkie Pathway in Drosophila Intestinal Growth
    1
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      DOI: 10.1016/j.devcel.2018.04.014

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    ncbi.nlm.nih.gov/pmc/articles/PMC7480018/
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Loss- or Gain-of-Function Mutations in ACOX1 Cause Axonal Loss via Different Mechanisms
    1
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      DOI: 10.1016/j.neuron.2020.02.021

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    ncbi.nlm.nih.gov/pmc/articles/PMC7289150/
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    Ankyrin Is An Intracellular Tether for TMC Mechanotransduction Channels
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      DOI: 10.1016/j.neuron.2020.03.026

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    sciencedirect.com/science/article/pii/S0896627320302336
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    An Optimized Chromatin Immunoprecipitation Protocol for Quantification of Protein-DNA Interactions
    1
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      DOI: 10.1016/j.xpro.2020.100020

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    Wnt-controlled sphingolipids modulate Anthrax Toxin Receptor palmitoylation to regulate oriented mitosis in zebrafish
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  50. rupress.org rupress.org
    Deorphanizing FAM19A proteins as pan-neurexin ligands with an unusual biosynthetic binding mechanism
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    Lats1/2 Sustain Intestinal Stem Cells and Wnt Activation through TEAD-Dependent and Independent Transcription
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    DNAJB6, a Key Factor in Neuronal Sensitivity to Amyloidogenesis
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    Ari-1 Regulates Myonuclear Organization Together with Parkin and Is Associated with Aortic Aneurysms
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    Pseudo-RNA-Binding Domains Mediate RNA Structure Specificity in Upstream of N-Ras
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    Excessive Cell Growth Causes Cytoplasm Dilution And Contributes to Senescence
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    Reprogramming Axial Level Identity to Rescue Neural-Crest-Related Congenital Heart Defects
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  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    The role of Rif1 in telomere length regulation is separable from its role in origin firing
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    Specialization of the chromatin remodeler RSC to mobilize partially-unwrapped nucleosomes
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    Whole brain delivery of an instability-prone Mecp2 transgene improves behavioral and molecular pathological defects in mouse models of Rett syndrome
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    An Allosteric Interaction Network Promotes Conformation State-Dependent Eviction of the Nas6 Assembly Chaperone from Nascent 26S Proteasomes
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    Mechanism of adrenergic Ca V 1.2 stimulation revealed by proximity proteomics
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    The MARCH6-SQLE Axis Controls Endothelial Cholesterol Homeostasis and Angiogenic Sprouting
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  64. elifesciences.org elifesciences.org
    HIV-1 Vpr induces cell cycle arrest and enhances viral gene expression by depleting CCDC137
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  65. www.nature.com www.nature.com
    Spt6 is a maintenance factor for centromeric CENP-A
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  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Prickle isoforms determine handedness of helical morphogenesis
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  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The tumor suppressor PTPRK promotes ZNRF3 internalization and is required for Wnt inhibition in the Spemann organizer
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  68. www.cell.com www.cell.com
    Gene-Specific Control of tRNA Expression by RNA Polymerase II
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  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The testis protein ZNF165 is a SMAD3 cofactor that coordinates oncogenic TGFβ signaling in triple-negative breast cancer
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  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases
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      V5 Antibody

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    Human cytomegalovirus interactome analysis identifies degradation hubs, domain associations and viral protein functions
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  72. Aug 2020
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    Context-Dependent Gene Regulation by Homeodomain Transcription Factor Complexes Revealed by Shape-Readout Deficient Proteins
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    LRRTMs Organize Synapses through Differential Engagement of Neurexin and PTPσ
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  75. Jan 2020
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    Rapid Generation of Somatic Mouse Mosaics with Locus-Specific, Stably Integrated Transgenic Elements
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    Unique-region phosphorylation targets LynA for rapid degradation, tuning its expression and signaling in myeloid cells
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    Antibody Therapy Targeting RAN Proteins Rescues C9 ALS/FTD Phenotypes in C9orf72 Mouse Model
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  79. www.jbc.org www.jbc.org
    The RING-type E3 ligase RNF186 ubiquitinates Sestrin-2 and thereby controls nutrient sensing
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  80. jcb.rupress.org jcb.rupress.org
    Developmental regulation of an organelle tether coordinates mitochondrial remodeling in meiosis
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  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cul4 ubiquitin ligase cofactor DCAF12 promotes neurotransmitter release and homeostatic plasticity
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    TRIM5α Restricts Flavivirus Replication by Targeting the Viral Protease for Proteasomal Degradation
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  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Casein kinase 1 family proteins promote Slimb-dependent Expanded degradation
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    Discovery and Development of TMPRSS6 Inhibitors Modulating Hepcidin Levels in Human Hepatocytes
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    Direct Gαq Gating Is the Sole Mechanism for TRPM8 Inhibition Caused by Bradykinin Receptor Activation
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    PPEF2 Opposes PINK1-Mediated Mitochondrial Quality Control by Dephosphorylating Ubiquitin
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  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The transcription factor odd-paired regulates temporal identity in transit-amplifying neural progenitors via an incoherent feed-forward loop
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    Identification of FUBP1 as a Long Tail Cancer Driver and Widespread Regulator of Tumor Suppressor and Oncogene Alternative Splicing
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    Naa10p Inhibits Beige Adipocyte-Mediated Thermogenesis through N-α-acetylation of Pgc1α
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    PRIMPOL-Mediated Adaptive Response Suppresses Replication Fork Reversal in BRCA-Deficient Cells
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    MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis
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    Comprehensive Genetic Characterization of Mitochondrial Ca2+ Uniporter Components Reveals Their Different Physiological Requirements In Vivo
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    Autism and Schizophrenia-Associated CYFIP1 Regulates the Balance of Synaptic Excitation and Inhibition
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    Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics
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    Oligoadenylate-Synthetase-Family Protein OASL Inhibits Activity of the DNA Sensor cGAS during DNA Virus Infection to Limit Interferon Production
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    Deregulated Expression of Mammalian lncRNA through Loss of SPT6 Induces R-Loop Formation, Replication Stress, and Cellular Senescence
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    Protein Barcodes Enable High-Dimensional Single-Cell CRISPR Screens
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    TFAP2 transcription factors are regulators of lipid droplet biogenesis
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    Cancer Mutations of the Tumor Suppressor SPOP Disrupt the Formation of Active, Phase-Separated Compartments
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    Non-invasive measurement of mRNA decay reveals translation initiation as the major determinant of mRNA stability
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    Triglycerides Promote Lipid Homeostasis during Hypoxic Stress by Balancing Fatty Acid Saturation
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    Quiescent Endothelial Cells Upregulate Fatty Acid β-Oxidation for Vasculoprotection via Redox Homeostasis
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    The Kinase IKKβ Regulates a STING- and NF-κB-Dependent Antiviral Response Pathway in Drosophila
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    Genome-wide Map of R-Loop-Induced Damage Reveals How a Subset of R-Loops Contributes to Genomic Instability
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    Biology and Clinical Implications of the 19q13 Aggressive Prostate Cancer Susceptibility Locus
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    Global Proteome Remodeling during ER Stress Involves Hac1-Driven Expression of Long Undecoded Transcript Isoforms
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    SET1A-Mediated Mono-Methylation at K342 Regulates YAP Activation by Blocking Its Nuclear Export and Promotes Tumorigenesis
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    Interactome Screening Identifies the ER Luminal Chaperone Hsp47 as a Regulator of the Unfolded Protein Response Transducer IRE1α
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    Phospholipase PLA2G6, a Parkinsonism-Associated Gene, Affects Vps26 and Vps35, Retromer Function, and Ceramide Levels, Similar to α-Synuclein Gain
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    The SS18-SSX Fusion Oncoprotein Hijacks BAF Complex Targeting and Function to Drive Synovial Sarcoma
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    Interrogation of Mammalian Protein Complex Structure, Function, and Membership Using Genome-Scale Fitness Screens
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    Phosphorylation-Mediated Clearance of Amyloid-like Assemblies in Meiosis
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    A-to-I RNA Editing Contributes to Proteomic Diversity in Cancer
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    Inflammation-Modulated Metabolic Reprogramming Is Required for DUOX-Dependent Gut Immunity in Drosophila
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    Ari-1 Regulates Myonuclear Organization Together with Parkin and Is Associated with Aortic Aneurysms
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    A compartmentalized signaling network mediates crossover control in meiosis
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    Directed Evolution to Engineer Monobody for FRET Biosensor Assembly and Imaging at Live-Cell Surface
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    Active Protection: Learning-Activated Raf/MAPK Activity Protects Labile Memory from Rac1-Independent Forgetting
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    A Proximity Labeling Strategy Provides Insights into the Composition and Dynamics of Lipid Droplet Proteomes
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    Organelle Specific O-Glycosylation Drives MMP14 Activation, Tumor Growth, and Metastasis
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    The Intellectual Disability and Schizophrenia Associated Transcription Factor TCF4 Is Regulated by Neuronal Activity and Protein Kinase A
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    Tumor-Suppressor Inactivation of GDF11 Occurs by Precursor Sequestration in Triple-Negative Breast Cancer
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    Multiple conserved cell adhesion protein interactions mediate neural wiring of a sensory circuit in C. elegans.
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  154. Nov 2017
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    CycD/Cdk4 and Discontinuities in Dpp Signaling Activate TORC1 in the Drosophila Wing Disc
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    Structural Mechanism for Modulation of Synaptic Neuroligin-Neurexin Signaling by MDGA Proteins
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    Phospho-Rasputin Stabilization by Sec16 Is Required for Stress Granule Formation upon Amino Acid Starvation
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    Distinct Ventral Pallidal Neural Populations Mediate Separate Symptoms of Depression
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    Xenopus laevis M18BP1 Directly Binds Existing CENP-A Nucleosomes to Promote Centromeric Chromatin Assembly
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    The complex of TRIP-Br1 and XIAP ubiquitinates and degrades multiple adenylyl cyclase isoforms
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    Autophagy-Dependent Shuttling of TBC1D5 Controls Plasma Membrane Translocation of GLUT1 and Glucose Uptake
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    Structure of Fam20A reveals a pseudokinase featuring a unique disulfide pattern and inverted ATP-binding
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    LSM12 and ME31B/DDX6 Define Distinct Modes of Posttranscriptional Regulation by ATAXIN-2 Protein Complex in Drosophila Circadian Pacemaker Neurons
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    Spt5 Plays Vital Roles in the Control of Sense and Antisense Transcription Elongation
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    Mitochondrial Ca2+ Uniporter Is a Mitochondrial Luminal Redox Sensor that Augments MCU Channel Activity
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    Expression of Terminal Effector Genes in Mammalian Neurons Is Maintained by a Dynamic Relay of Transient Enhancers
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  169. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Satb2 determines miRNA expression and long-term memory in the adult central nervous system
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    Ligand and Target Discovery by Fragment-Based Screening in Human Cells
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  171. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Filamin, a synaptic organizer in Drosophila, determines glutamate receptor composition and membrane growth
    1
    1. scibot 08 Nov 2017
      AB_2556564

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      (Thermo Fisher Scientific Cat# R960-25, RRID:AB_2556564)

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      RRID:AB_2556564
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    ncbi.nlm.nih.gov/pmc/articles/PMC5173320/
  172. www.sciencedirect.com www.sciencedirect.com
    A Multi-step Transcriptional and Chromatin State Cascade Underlies Motor Neuron Programming from Embryonic Stem Cells
    1
    1. scibot 08 Nov 2017
      AB_2556564

      Curator: @gabimpine

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      (Thermo Fisher Scientific Cat# R960-25, RRID:AB_2556564)

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      RRID:AB_2556564 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1934590916304027
  173. www.sciencedirect.com www.sciencedirect.com
    Biallelic TBCD Mutations Cause Early-Onset Neurodegenerative Encephalopathy
    1
    1. scibot 08 Nov 2017
      AB_2556564

      Curator: @kaitlinsung

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      (Thermo Fisher Scientific Cat# R960-25, RRID:AB_2556564)

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      RRID:AB_2556564 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S0002929716303287
  174. www.sciencedirect.com www.sciencedirect.com
    Proteomic Analysis of Unbounded Cellular Compartments: Synaptic Clefts
    1
    1. scibot 08 Nov 2017
      AB_2556564

      Curator: @gabimpine

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      (Thermo Fisher Scientific Cat# R960-25, RRID:AB_2556564)

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      RRID:AB_2556564 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S0092867416309916
  175. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Differential coexpression of FoxP1, FoxP2, and FoxP4 in the Zebra Finch (Taeniopygia guttata) song system
    1
    1. scibot 08 Nov 2017
      V5

      Curator: @gabimpine

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      (Thermo Fisher Scientific Cat# R960-25, RRID:AB_2556564)

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      RRID:AB_2556564 RRIDCUR:Missing
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    onlinelibrary.wiley.com/doi/10.1002/cne.23731/full