298 Matching Annotations
  1. Jan 2022
  2. www.sciencedirect.com www.sciencedirect.com
    SURF4-induced tubular ERGIC selectively expedites ER-to-Golgi transport
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    1. scibot 26 Jan 2022
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      DOI: 10.1016/j.devcel.2021.12.018

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    sciencedirect.com/science/article/pii/S1534580721010388
  3. Dec 2021
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    Anti-recombination function of MutSα restricts telomere extension by ALT-associated homology-directed repair
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      DOI: 10.1016/j.celrep.2021.110088

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    sciencedirect.com/science/article/pii/S2211124721015795
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    Redox-sensitive cyclophilin A elicits chemoresistance through realigning cellular oxidative status in colorectal cancer
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    1. scibot 01 Dec 2021
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      DOI: 10.1016/j.celrep.2021.110069

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    sciencedirect.com/science/article/pii/S2211124721015552
  6. Nov 2021
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Acetyl-CoA derived from hepatic mitochondrial fatty acid β-oxidation aggravates inflammation by enhancing p65 acetylation
    1
    1. scibot 09 Nov 2021
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      DOI: 10.1016/j.isci.2021.103244

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    ncbi.nlm.nih.gov/pmc/articles/PMC8551082/
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    ORF3a of SARS-CoV-2 promotes lysosomal exocytosis-mediated viral egress
    1
    1. scibot 09 Nov 2021
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    sciencedirect.com/science/article/pii/S1534580721008078
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    A nonautophagic role of ATG5 in regulating cell growth by targeting c-Myc for proteasome-mediated degradation
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    1. scibot 09 Nov 2021
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      DOI: 10.1016/j.isci.2021.103296

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    sciencedirect.com/science/article/pii/S2589004221012657
  10. www.nature.com www.nature.com
    AKIRIN2 controls the nuclear import of proteasomes in vertebrates
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    1. scibot 06 Nov 2021
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      DOI: 10.1038/s41586-021-04035-8

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    nature.com/articles/s41586-021-04035-8
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    Crystal structure of the Tspan15 LEL domain reveals a conserved ADAM10 binding site
    1
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    sciencedirect.com/science/article/pii/S0969212621003750
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    RNA-binding protein FXR1 drives cMYC translation by recruiting eIF4F complex to the translation start site
    1
    1. scibot 03 Nov 2021
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      DOI: 10.1016/j.celrep.2021.109934

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    sciencedirect.com/science/article/pii/S2211124721014078
  13. Oct 2021
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    Mitophagy antagonism by ZIKV reveals Ajuba as a regulator of PINK1 signaling, PKR-dependent inflammation, and viral invasion of tissues
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    1. scibot 27 Oct 2021
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      DOI: 10.1016/j.celrep.2021.109888

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    sciencedirect.com/science/article/pii/S2211124721013589
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    Mechanistic Insights into COVID-19 by Global Analysis of the SARS-CoV-2 3CLpro Substrate Degradome
    1
    1. scibot 23 Oct 2021
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    ncbi.nlm.nih.gov/pmc/articles/PMC8501228/
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    Glycogen accumulation and phase separation drives liver tumor initiation
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    1. scibot 22 Oct 2021
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    sciencedirect.com/science/article/pii/S0092867421011752
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    ROR and RYK extracellular region structures suggest that receptor tyrosine kinases have distinct WNT-recognition modes
    1
    1. scibot 21 Oct 2021
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    sciencedirect.com/science/article/pii/S2211124721012985
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    Akt regulates Sox10 expression to control oligodendrocyte differentiation via phosphorylating FoxO1
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    1. scibot 09 Oct 2021
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      DOI: 10.1523/JNEUROSCI.2432-20.2021

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    jneurosci.org/content/41/39/8163
  19. Sep 2021
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    Effect of Three NR3C1 mutations in Pathogenesis of Pituitary ACTH Adenoma
    1
    1. scibot 30 Sep 2021
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      DOI: 10.1210/endocr/bqab167

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    academic.oup.com/endo/article/162/11/bqab167/6357044
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    H3K4 di-methylation governs smooth muscle lineage identity and promotes vascular homeostasis by restraining plasticity
    1
    1. scibot 28 Sep 2021
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    sciencedirect.com/science/article/pii/S1534580721006821
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    A hydride transfer complex reprograms NAD metabolism and bypasses senescence
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      DOI: 10.1016/j.molcel.2021.08.028

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    sciencedirect.com/science/article/pii/S109727652100695X
  23. Aug 2021
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    YAP regulates alveolar epithelial cell differentiation and AGER via NFIB/KLF5/NKX2-1
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    1. scibot 24 Aug 2021
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      DOI: 10.1016/j.isci.2021.102967

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    sciencedirect.com/science/article/pii/S2589004221009354
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    Extracellular vesicle-based interorgan transport of mitochondria from energetically stressed adipocytes
    1
    1. scibot 21 Aug 2021
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      DOI: 10.1016/j.cmet.2021.08.002

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    sciencedirect.com/science/article/pii/S155041312100365X
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    Actinin BioID reveals sarcomere crosstalk with oxidative metabolism through interactions with IGF2BP2
    1
    1. scibot 15 Aug 2021
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      DOI: 10.1016/j.celrep.2021.109512

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    sciencedirect.com/science/article/pii/S2211124721009426
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    Compartmentalization-Aided Interaction Screening Reveals Extensive High-Order Complexes within the SARS-CoV-2 Proteome
    1
    1. scibot 15 Aug 2021
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      DOI: 10.1016/j.celrep.2021.109482

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    sciencedirect.com/science/article/pii/S2211124721009098
  28. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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    1. scibot 14 Aug 2021
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      DOI: 10.1111/bph.15490

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15490
  29. www.sciencedirect.com www.sciencedirect.com
    Artemisinin inhibits NRas palmitoylation by targeting the protein acyltransferase ZDHHC6
    1
    1. scibot 07 Aug 2021
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      DOI: 10.1016/j.chembiol.2021.07.012

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    sciencedirect.com/science/article/pii/S2451945621003524
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    Isthmin-1 is an adipokine that promotes glucose uptake and improves glucose tolerance and hepatic steatosis
    1
    1. scibot 04 Aug 2021
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      DOI: 10.1016/j.cmet.2021.07.010

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    sciencedirect.com/science/article/pii/S1550413121003260
  31. Jul 2021
  32. www.sciencedirect.com www.sciencedirect.com
    TRIM8 modulates the EWS/FLI oncoprotein to promote survival in Ewing sarcoma
    1
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    sciencedirect.com/science/article/pii/S1535610821003809
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Specialization of the Drosophila nuclear export family protein Nxf3 for piRNA precursor export
    1
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      DOI: 10.1101/gad.328690.119

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    ncbi.nlm.nih.gov/pmc/articles/PMC6719614/
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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      DOI: 10.1016/j.celrep.2018.07.105

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    ncbi.nlm.nih.gov/pmc/articles/PMC6173831/
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of Putative Receptors for the Novel Adipokine CTRP3 Using Ligand-Receptor Capture Technology
    2
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      DOI: 10.1371/journal.pone.0164593

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    ncbi.nlm.nih.gov/pmc/articles/PMC5058508/
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Extracellular domain shedding of the ALK receptor mediates neuroblastoma cell migration
    1
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      DOI: 10.1016/j.celrep.2021.109363

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    ncbi.nlm.nih.gov/pmc/articles/PMC8328392/
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    FANCI functions as a repair/apoptosis switch in response to DNA crosslinks
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    sciencedirect.com/science/article/pii/S1534580721005177
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    The RAS GTPase RIT1 compromises mitotic fidelity through spindle assembly checkpoint suppression
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      DOI: 10.1016/j.cub.2021.06.030

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    sciencedirect.com/science/article/pii/S0960982221008253
  39. Jun 2021
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    Vaccinia virus E3 prevents sensing of Z-RNA to block ZBP1-dependent necroptosis
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      DOI: 10.1016/j.chom.2021.05.009

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    sciencedirect.com/science/article/pii/S1931312821002377
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    Tripartite motif 16 ameliorates nonalcoholic steatohepatitis by promoting the degradation of phospho-TAK1
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      DOI: 10.1016/j.cmet.2021.05.019

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    sciencedirect.com/science/article/pii/S1550413121002709
  42. May 2021
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      DOI: 10.1111/bph.15340

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15340
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    Divergent and self-reactive immune responses in the CNS of COVID-19 patients with neurological symptoms
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      DOI: 10.1016/j.xcrm.2021.100288

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    sciencedirect.com/science/article/pii/S2666379121001166
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    Nucleotide Binding, Evolutionary Insights, and Interaction Partners of the Pseudokinase Unc-51-like Kinase 4
    1
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      DOI: 10.1016/j.str.2020.07.016

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    sciencedirect.com/science/article/pii/S096921262030280X
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    A Non-canonical PDK1-RSK Signal Diminishes Pro-caspase-8-Mediated Necroptosis Blockade
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      DOI: 10.1016/j.molcel.2020.09.004

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    sciencedirect.com/science/article/pii/S1097276520306122
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    TBK1-Mediated DRP1 Targeting Confers Nucleic Acid Sensing to Reprogram Mitochondrial Dynamics and Physiology
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      DOI: 10.1016/j.molcel.2020.10.018

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    sciencedirect.com/science/article/pii/S1097276520307255
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    Ectosomal PKM2 Promotes HCC by Inducing Macrophage Differentiation and Remodeling the Tumor Microenvironment
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      DOI: 10.1016/j.molcel.2020.05.004

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    sciencedirect.com/science/article/pii/S1097276520303051
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    The Rag GTPase Regulates the Dynamic Behavior of TSC Downstream of Both Amino Acid and Growth Factor Restriction
    1
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    The Immunoglobulin Superfamily Receptome Defines Cancer-Relevant Networks Associated with Clinical Outcome
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    SETD2 Restricts Prostate Cancer Metastasis by Integrating EZH2 and AMPK Signaling Pathways
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    Altered RNA Splicing by Mutant p53 Activates Oncogenic RAS Signaling in Pancreatic Cancer
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    Targeted degradation of transcription factors by TRAFTACs: TRAnscription Factor TArgeting Chimeras
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  57. Mar 2021
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    Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape
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  60. Feb 2021
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    Liver Immune Profiling Reveals Pathogenesis and Therapeutics for Biliary Atresia
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    Systematic Identification of Regulators of Oxidative Stress Reveals Non-canonical Roles for Peroxisomal Import and the Pentose Phosphate Pathway
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  67. Jan 2021
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  69. Dec 2020
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  71. Nov 2020
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    Polyunsaturated Fatty Acids Influence LPS-Induced Inflammation of Fish Macrophages Through Differential Modulation of Pathogen Recognition and p38 MAPK/NF-κB Signaling
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  73. Oct 2020
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    Matrix Rigidity Controls Epithelial-Mesenchymal Plasticity and Tumor Metastasis via a Mechanoresponsive EPHA2/LYN Complex
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  75. Sep 2020
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    Macrophage K63-Linked Ubiquitination of YAP Promotes Its Nuclear Localization and Exacerbates Atherosclerosis
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    The Interaction of the Tumor Suppressor FAM46C with p62 and FNDC3 Proteins Integrates Protein and Secretory Homeostasis
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    Systematic Identification of Regulators of Oxidative Stress Reveals Non-canonical Roles for Peroxisomal Import and the Pentose Phosphate Pathway
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    The Natural Compound Notopterol Binds and Targets JAK2/3 to Ameliorate Inflammation and Arthritis
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    Ubiquitin-Conjugating Enzyme 2S Enhances Viral Replication by Inhibiting Type I IFN Production through Recruiting USP15 to Deubiquitinate TBK1
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    The Kinase Activity of Drosophila BubR1 Is Required for Insulin Signaling-Dependent Stem Cell Maintenance
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    Interaction of Axonal Chondrolectin with Collagen XIXa1 Is Necessary for Precise Neuromuscular Junction Formation
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    Regulation of EZH2 by SMYD2-Mediated Lysine Methylation Is Implicated in Tumorigenesis
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    Systematic Identification of Host Cell Regulators of Legionella pneumophila Pathogenesis Using a Genome-wide CRISPR Screen
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    Histone deacetylase 6 promotes growth of glioblastoma through the MKK7/JNK/c‐Jun signaling pathway
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    Circular RNA circPICALM sponges miR-1265 to inhibit bladder cancer metastasis and influence FAK phosphorylation
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    Zc3h10 Acts as a Transcription Factor and Is Phosphorylated to Activate the Thermogenic Program
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    γ-6-Phosphogluconolactone, a Byproduct of the Oxidative Pentose Phosphate Pathway, Contributes to AMPK Activation through Inhibition of PP2A
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    Rinf Regulates Pluripotency Network Genes and Tet Enzymes in Embryonic Stem Cells
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  97. www.sciencedirect.com www.sciencedirect.com
    Heat Shock Factor 1 Is a Direct Antagonist of AMP-Activated Protein Kinase
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      RRID:AB_2572291

      DOI: 10.1016/j.molcel.2019.08.021

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    Targeting 7-Dehydrocholesterol Reductase Integrates Cholesterol Metabolism and IRF3 Activation to Eliminate Infection
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    1. scibot 13 Jan 2020
      RRID:AB_2572291

      DOI: 10.1016/j.immuni.2019.11.015

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    sciencedirect.com/science/article/pii/S1074761319304960
  99. www.sciencedirect.com www.sciencedirect.com
    N-WASP Control of LPAR1 Trafficking Establishes Response to Self-Generated LPA Gradients to Promote Pancreatic Cancer Cell Metastasis
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    1. scibot 13 Jan 2020
      RRID:AB_2572291

      DOI: 10.1016/j.devcel.2019.09.018

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    sciencedirect.com/science/article/pii/S1534580719307749
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    1. scibot 13 Jan 2020
      RRID:AB_2572291

      DOI: 10.1016/j.chembiol.2019.03.009

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    sciencedirect.com/science/article/pii/S2451945619301059
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    1. scibot 13 Jan 2020
      RRID:AB_2572291

      DOI: 10.1016/j.chembiol.2019.03.012

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    sciencedirect.com/science/article/pii/S2451945619301084
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      RRID:AB_2572291

      DOI: 10.1016/j.immuni.2019.02.009

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    1. scibot 12 Jan 2020
      RRID:AB_2572291

      DOI: 10.1016/j.celrep.2019.01.029

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    sciencedirect.com/science/article/pii/S2211124719300385
  104. Nov 2018
  105. www.sciencedirect.com www.sciencedirect.com
    Lin28 Signaling Supports Mammalian PNS and CNS Axon Regeneration
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    1. scibot 05 Nov 2018
      RRID:AB_2572291

      Curator: @evieth

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    Metformin Promotes Antitumor Immunity via Endoplasmic-Reticulum-Associated Degradation of PD-L1
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    AMPK-Mediated BECN1 Phosphorylation Promotes Ferroptosis by Directly Blocking System Xc– Activity
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      RRID:AB_2572291

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    Dual Requirement of CHD8 for Chromatin Landscape Establishment and Histone Methyltransferase Recruitment to Promote CNS Myelination and Repair
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      RRID:AB_2572291

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    Intersubunit Crosstalk in the Rag GTPase Heterodimer Enables mTORC1 to Respond Rapidly to Amino Acid Availability
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      RRID:AB_2572291

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    Acid Suspends the Circadian Clock in Hypoxia through Inhibition of mTOR
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      RRID:AB_2572291

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    sciencedirect.com/science/article/pii/S0092867418305865
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    AIDA Selectively Mediates Downregulation of Fat Synthesis Enzymes by ERAD to Retard Intestinal Fat Absorption and Prevent Obesity
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    1. scibot 05 Nov 2018
      RRID:AB_2572291

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    sciencedirect.com/science/article/pii/S1550413118301323
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    γ-Secretase Inhibition Lowers Plasma Triglyceride-Rich Lipoproteins by Stabilizing the LDL Receptor
    1
    1. scibot 05 Nov 2018
      RRID:AB_2572291

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    sciencedirect.com/science/article/pii/S1550413118301219
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    lncRNA Epigenetic Landscape Analysis Identifies EPIC1 as an Oncogenic lncRNA that Interacts with MYC and Promotes Cell-Cycle Progression in Cancer
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    1. scibot 05 Nov 2018
      RRID:AB_2572291

      Curator: @evieth

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    sciencedirect.com/science/article/pii/S1535610818301107
  115. academic.oup.com academic.oup.com
    GADD45a Promotes Active DNA Demethylation of the MMP-9 Promoter via Base Excision Repair Pathway in AGEs-Treated Keratinocytes and in Diabetic Male Rat Skin
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      AB_2572291

      Curator: @evieth

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      (Cell Signaling Technology Cat# 14793, RRID:AB_2572291)

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    academic.oup.com/endo/article/159/2/1172/4736306
  116. www.sciencedirect.com www.sciencedirect.com
    Binding of PLD2-Generated Phosphatidic Acid to KIF5B Promotes MT1-MMP Surface Trafficking and Lung Metastasis of Mouse Breast Cancer Cells
    1
    1. scibot 05 Nov 2018
      RRID:AB_2572291

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      (Cell Signaling Technology Cat# 14793, RRID:AB_2572291)

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    sciencedirect.com/science/article/pii/S1534580717307359