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  1. Aug 2021
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    sciencedirect.com/science/article/pii/S1535610818305361
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    ZMYND8-regulated IRF8 transcription axis is an acute myeloid leukemia dependency
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    sciencedirect.com/science/article/pii/S1097276521005876
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    Gestational Diabetes Epigenetically Reprograms the Cart Promoter in Fetal Ovary, Causing Subfertility in Adult Life
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      DOI: 10.1210/en.2019-00319

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    academic.oup.com/endo/article/160/7/1684/5506444
  5. Jul 2021
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    1. scibot 31 Jul 2021
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    sciencedirect.com/science/article/pii/S153561081830535X
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    ncbi.nlm.nih.gov/pmc/articles/PMC6342284/
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    sciencedirect.com/science/article/pii/S2211124718317984
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    ncbi.nlm.nih.gov/pmc/articles/PMC5985145/
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    1. scibot 27 Jul 2021
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    sciencedirect.com/science/article/pii/S0012160618305153
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    Multiple polycomb epigenetic regulatory proteins are active in normal and regenerating adult olfactory epithelium
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  12. Jun 2021
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    BAP1 enhances Polycomb repression by counteracting widespread H2AK119ub1 deposition and chromatin condensation
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    sciencedirect.com/science/article/pii/S1097276521005001
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    Correct dosage of X chromosome transcription is controlled by a nuclear pore component
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    sciencedirect.com/science/article/pii/S2211124721005957
  15. May 2021
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    Derivation of Intermediate Pluripotent Stem Cells Amenable to Primordial Germ Cell Specification
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    sciencedirect.com/science/article/pii/S1934590920305415
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    Enhancers are activated by p300/CBP activity-dependent PIC assembly, RNAPII recruitment, and pause release
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    Opposing Effects of Cohesin and Transcription on CTCF Organization Revealed by Super-resolution Imaging
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    H3 K27M and EZHIP Impede H3K27-Methylation Spreading by Inhibiting Allosterically Stimulated PRC2
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    Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer
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    sciencedirect.com/science/article/pii/S1097276520302690
  21. Apr 2021
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    Energy status dictates PD-L1 protein abundance and anti-tumor immunity to enable checkpoint blockade
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    sciencedirect.com/science/article/pii/S109727652100232X
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    Large-Scale Topological Changes Restrain Malignant Progression in Colorectal Cancer
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    sciencedirect.com/science/article/pii/S0092867420309387
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    Metabolic Regulation of the Epigenome Drives Lethal Infantile Ependymoma
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    sciencedirect.com/science/article/pii/S0092867420305535
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    A hotspot mutation in transcription factor IKZF3 drives B cell neoplasia via transcriptional dysregulation
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    sciencedirect.com/science/article/pii/S1535610821001057
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    Cholesterol Pathway Inhibition Induces TGF-β Signaling to Promote Basal Differentiation in Pancreatic Cancer
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    sciencedirect.com/science/article/pii/S1535610820304268
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    Distinct PRC2 subunits regulate maintenance and establishment of Polycomb repression during differentiation
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      DOI: 10.1016/j.molcel.2021.03.038

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    Multi-omic profiling of pituitary thyrotropic cells and progenitors
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    SETD2 Restricts Prostate Cancer Metastasis by Integrating EZH2 and AMPK Signaling Pathways
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    SETD5-Coordinated Chromatin Reprogramming Regulates Adaptive Resistance to Targeted Pancreatic Cancer Therapy
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    UTX promotes CD8+ T cell-mediated antiviral defenses but reduces T cell durability
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    Dual targeting of the epigenome via FACT complex and histone deacetylase is a potent treatment strategy for DIPG
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    The SMC5/6 complex compacts and silences unintegrated HIV-1 DNA and is antagonized by Vpr
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    mTORC1 stimulates cell growth through SAM synthesis and m6A mRNA-dependent control of protein synthesis
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  35. www.cell.com www.cell.com
    Gut microbial metabolites facilitate anticancer therapy efficacy by modulating cytotoxic CD8+ T cell immunity
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    cell.com/cell-metabolism/fulltext/S1550-4131(21)00109-1
  36. Mar 2021
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Embryonic Stem-Cell-Derived Extracellular Vesicles Maintain ESC Stemness by Activating FAK
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  38. Feb 2021
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    Histone H3.3G34-Mutant Interneuron Progenitors Co-opt PDGFRA for Gliomagenesis
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    TASOR is a pseudo-PARP that directs HUSH complex assembly and epigenetic transposon control
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    Regional identity of human neural stem cells determines oncogenic responses to histone H3.3 mutants
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    Definition of a small core transcriptional circuit regulated by AML1-ETO
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    cell.com/molecular-cell/fulltext/S1097-2765(20)30897-2
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    Chromatin dysregulation associated with NSD1 mutation in head and neck squamous cell carcinoma
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    Competition between PRC2.1 and 2.2 subcomplexes regulates PRC2 chromatin occupancy in human stem cells
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    An acetyl-histone vulnerability in PI3K/AKT inhibition-resistant cancers is targetable by both BET and HDAC inhibitors
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      DOI: 10.1016/j.celrep.2021.108744

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  46. Jan 2021
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Stage-specific roles of Ezh2 and Retinoic acid signaling ensure calvarial bone lineage commitment.
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  48. Dec 2020
  49. elifesciences.org elifesciences.org
    Efficient chromatin accessibility mapping in situ by nucleosome-tethered tagmentation
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      DOI: 10.7554/eLife.63274

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  50. Nov 2020
  51. www.sciencedirect.com www.sciencedirect.com
    H3K27M in Gliomas Causes a One-Step Decrease in H3K27 Methylation and Reduced Spreading within the Constraints of H3K36 Methylation
    1
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      DOI: 10.1016/j.celrep.2020.108390

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    sciencedirect.com/science/article/pii/S2211124720313796
  52. www.cell.com www.cell.com
    Formation of the CenH3-Deficient Holocentromere in Lepidoptera Avoids Active Chromatin
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      DOI: 10.1016/j.cub.2020.09.078

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    cell.com/current-biology/abstract/S0960-9822(20)31448-2
  53. www.sciencedirect.com www.sciencedirect.com
    ARID1A Mutations Promote P300-Dependent Endometrial Invasion through Super-Enhancer Hyperacetylation
    1
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      DOI: 10.1016/j.celrep.2020.108366

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  54. www.sciencedirect.com www.sciencedirect.com
    Metabolic Reprogramming Induces Germinal Center B Cell Differentiation through Bcl6 Locus Remodeling
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      DOI: 10.1016/j.celrep.2020.108333

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  55. Oct 2020
  56. www.cell.com www.cell.com
    Senescence Induced by BMI1 Inhibition Is a Therapeutic Vulnerability in H3K27M-Mutant DIPG
    1
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  57. www.sciencedirect.com www.sciencedirect.com
    Bone Morphogenic Proteins Are Immunoregulatory Cytokines Controlling FOXP3+ Treg Cells
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  58. Sep 2020
  59. www.sciencedirect.com www.sciencedirect.com
    Mutant EZH2 Induces a Pre-malignant Lymphoma Niche by Reprogramming the Immune Response
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  60. www.sciencedirect.com www.sciencedirect.com
    Global Regulatory DNA Potentiation by SMARCA4 Propagates to Selective Gene Expression Programs via Domain-Level Remodeling
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      DOI: 10.1016/j.celrep.2020.107676

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  61. www.sciencedirect.com www.sciencedirect.com
    Domain Model Explains Propagation Dynamics and Stability of Histone H3K27 and H3K36 Methylation Landscapes
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    A Dimeric Structural Scaffold for PRC2-PCL Targeting to CpG Island Chromatin
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      DOI: 10.1016/j.molcel.2019.12.019

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  63. www.sciencedirect.com www.sciencedirect.com
    Dissecting Murine Muscle Stem Cell Aging through Regeneration Using Integrative Genomic Analysis
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  64. www.sciencedirect.com www.sciencedirect.com
    Heterochromatin-Driven Nuclear Softening Protects the Genome against Mechanical Stress-Induced Damage
    1
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  65. www.sciencedirect.com www.sciencedirect.com
    Epigenetic Silencing of CDR1as Drives IGF2BP3-Mediated Melanoma Invasion and Metastasis
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      DOI: 10.1016/j.ccell.2019.12.007

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  66. www.sciencedirect.com www.sciencedirect.com
    EZH2 Inhibition Sensitizes CARM1-High, Homologous Recombination Proficient Ovarian Cancers to PARP Inhibition
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      DOI: 10.1016/j.ccell.2019.12.015

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  67. www.sciencedirect.com www.sciencedirect.com
    Cdk1 Controls Global Epigenetic Landscape in Embryonic Stem Cells
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    NeuroD1 Dictates Tumor Cell Differentiation in Medulloblastoma
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  69. www.sciencedirect.com www.sciencedirect.com
    A Deregulated HOX Gene Axis Confers an Epigenetic Vulnerability in KRAS-Mutant Lung Cancers
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      DOI: 10.1016/j.ccell.2020.03.004

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  70. www.cell.com www.cell.com
    Aging Suppresses Skin-Derived Circulating SDF1 to Promote Full-Thickness Tissue Regeneration
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      DOI: 10.1016/j.celrep.2018.08.054

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    cell.com/cell-reports/fulltext/S2211-1247(18)31340-8
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    Super Elongation Complex as a Targetable Dependency in Diffuse Midline Glioma
    1
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      Tri-Methyl-Histone H3 (Lys27) rabbit mAb

      DOI: 10.1016/j.celrep.2020.03.049

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  72. www.sciencedirect.com www.sciencedirect.com
    Methionine Metabolism Shapes T Helper Cell Responses through Regulation of Epigenetic Reprogramming
    1
    1. scibot 04 Sep 2020
      Rabbit monoclonal anti-mouse Tri-methyl-Histone H3 (Lys27) (1:2000 dilution)

      DOI: 10.1016/j.cmet.2020.01.006

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  73. rupress.org rupress.org
    Glioma stem-like cells evade interferon suppression through MBD3/NuRD complex–mediated STAT1 downregulation
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      DOI: 10.1084/jem.20191340

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    rupress.org/jem/article/217/5/e20191340/151561/Glioma-stem-like-cells-evade-interferon
  74. mcr.aacrjournals.org mcr.aacrjournals.org
    Dual Regulation of Histone Methylation by mTOR Complexes Controls Glioblastoma Tumor Cell Growth via EZH2 and SAM
    1
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      H3K27me3

      DOI: 10.1158/1541-7786.MCR-20-0024

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  75. Aug 2020
  76. www.sciencedirect.com www.sciencedirect.com
    Genome-wide R-loop Landscapes during Cell Differentiation and Reprogramming
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      RRID:AB_6216029

      DOI: 10.1016/j.celrep.2020.107870

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  77. Jan 2020
  78. www.sciencedirect.com www.sciencedirect.com
    One-Carbon Metabolism Supports S-Adenosylmethionine and Histone Methylation to Drive Inflammatory Macrophages
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      DOI: 10.1016/j.molcel.2019.06.039

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    A Functional Link between Nuclear RNA Decay and Transcriptional Control Mediated by the Polycomb Repressive Complex 2
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    1. scibot 13 Jan 2020
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      DOI: 10.1016/j.celrep.2019.10.011

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  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Antagonistic interaction between Ezh2 and Arid1a coordinates root patterning and development via Cdkn2a in mouse molars
    1
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      RRID:AB_2616029

      DOI: 10.7554/eLife.46426

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    Rapid Generation of Somatic Mouse Mosaics with Locus-Specific, Stably Integrated Transgenic Elements
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      DOI: 10.1016/j.cell.2019.08.013

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    EED-Targeted PROTACs Degrade EED, EZH2, and SUZ12 in the PRC2 Complex
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      DOI: 10.1016/j.chembiol.2019.11.004

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    Quantitative Multiplexed ChIP Reveals Global Alterations that Shape Promoter Bivalency in Ground State Embryonic Stem Cells
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      DOI: 10.1016/j.celrep.2019.08.046

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    DEAD-Box Helicase 18 Counteracts PRC2 to Safeguard Ribosomal DNA in Pluripotency Regulation
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      DOI: 10.1016/j.celrep.2019.12.021

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    An Evolutionarily Conserved Function of Polycomb Silences the MHC Class I Antigen Presentation Pathway and Enables Immune Evasion in Cancer
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      DOI: 10.1016/j.ccell.2019.08.008

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    PRC2.1 and PRC2.2 Synergize to Coordinate H3K27 Trimethylation
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      DOI: 10.1016/j.molcel.2019.08.012

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    Regulation of EZH2 by SMYD2-Mediated Lysine Methylation Is Implicated in Tumorigenesis
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      DOI: 10.1016/j.celrep.2019.10.004

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    lncRNA-Induced Spread of Polycomb Controlled by Genome Architecture, RNA Abundance, and CpG Island DNA
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      DOI: 10.1016/j.molcel.2019.05.028

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    Quantification of Proteins and Histone Marks in Drosophila Embryos Reveals Stoichiometric Relationships Impacting Chromatin Regulation
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      DOI: 10.1016/j.devcel.2019.09.011

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    Active and Repressed Chromatin Domains Exhibit Distinct Nucleosome Segregation during DNA Replication
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      DOI: 10.1016/j.cell.2019.10.009

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    PPEF2 Opposes PINK1-Mediated Mitochondrial Quality Control by Dephosphorylating Ubiquitin
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      DOI: 10.1016/j.celrep.2019.10.130

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    Polycomb Group Proteins Regulate Chromatin Architecture in Mouse Oocytes and Early Embryos
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    HUMAN TROPHOBLAST DIFFERENTIATION IS ASSOCIATED WITH PROFOUND GENE REGULATORY AND EPIGENETIC CHANGES
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    Small Molecule Inhibitors of KDM5 Histone Demethylases Increase the Radiosensitivity of Breast Cancer Cells Overexpressing JARID1B
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    Histone H2AK119 Mono-Ubiquitination Is Essential for Polycomb-Mediated Transcriptional Repression
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    The Short Chain Fatty Acid Butyrate Imprints an Antimicrobial Program in Macrophages
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    Targeting Epigenetic Crosstalk as a Therapeutic Strategy for EZH2-Aberrant Solid Tumors
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    EZH2-Mediated Primary Cilium Deconstruction Drives Metastatic Melanoma Formation
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    MicroRNAs Overcome Cell Fate Barrier by Reducing EZH2-Controlled REST Stability during Neuronal Conversion of Human Adult Fibroblasts
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    A Somatically Acquired Enhancer of the Androgen Receptor Is a Noncoding Driver in Advanced Prostate Cancer
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    Targeting the Senescence-Overriding Cooperative Activity of Structurally Unrelated H3K9 Demethylases in Melanoma
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    The SS18-SSX Oncoprotein Hijacks KDM2B-PRC1.1 to Drive Synovial Sarcoma
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    A Family of Vertebrate-Specific Polycombs Encoded by the LCOR/LCORL Genes Balance PRC2 Subtype Activities
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    The H3K36me2 Methyltransferase Nsd1 Demarcates PRC2-Mediated H3K27me2 and H3K27me3 Domains in Embryonic Stem Cells
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    A Non-canonical BCOR-PRC1.1 Complex Represses Differentiation Programs in Human ESCs
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    The Elongation Factor Spt6 Maintains ESC Pluripotency by Controlling Super-Enhancers and Counteracting Polycomb Proteins
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    H3.3K27M Cooperates with Trp53 Loss and PDGFRA Gain in Mouse Embryonic Neural Progenitor Cells to Induce Invasive High-Grade Gliomas
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  120. Nov 2017
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    Ubiquitination-Deficient Mutations in Human Piwi Cause Male Infertility by Impairing Histone-to-Protamine Exchange during Spermiogenesis
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    Gene Resistance to Transcriptional Reprogramming following Nuclear Transfer Is Directly Mediated by Multiple Chromatin-Repressive Pathways
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