308 Matching Annotations
  1. Nov 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Acute multi-level response to defective de novo chromatin assembly in S-phase
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    1. scibot 14 Nov 2024
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    sciencedirect.com/science/article/pii/S1097276524008633
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    BRG1 programs PRC2-complex repression and controls oligodendrocyte differentiation and remyelination
    1
    1. scibot 07 Nov 2024
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      DOI: 10.1083/jcb.202310143

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    pmc.ncbi.nlm.nih.gov/articles/PMC11040499/
  4. Oct 2024
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    HOXDeRNA activates a cancerous transcription program and super enhancers via genome-wide binding
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    sciencedirect.com/science/article/pii/S1097276524007755
  6. link.springer.com link.springer.com
    Multiplexed chromatin immunoprecipitation sequencing for quantitative study of histone modifications and chromatin factors
    1
    1. scibot 08 Oct 2024
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    link.springer.com/article/10.1038/s41596-024-01058-z
  7. aacrjournals.org aacrjournals.org
    H3.3 G34W Promotes Growth and Impedes Differentiation of Osteoblast-Like Mesenchymal Progenitors in Giant Cell Tumor of Bone
    1
    1. scibot 02 Oct 2024
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      DOI: 10.1158/2159-8290.CD-20-0461

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    aacrjournals.org/cancerdiscovery/article/10/12/1968/2414/H3-3-G34W-Promotes-Growth-and-Impedes
  8. Sep 2024
  9. analyticalsciencejournals.onlinelibrary.wiley.com analyticalsciencejournals.onlinelibrary.wiley.com
    Epigenetic alternations in the SYP and DLG4 genes due to low-level methylmercury exposure during neuronal differentiation in vitro
    1
    1. scibot 27 Sep 2024
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      DOI: 10.1002/jat.4690

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    analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/jat.4690
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    Reduction of Global H3K27me3 Enhances HER2/ErbB2 Targeted Therapy
    1
    1. scibot 25 Sep 2024
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    sciencedirect.com/science/article/pii/S2211124719311672
  11. www.sciencedirect.com www.sciencedirect.com
    Hyperactivating EZH2 to augment H3K27me3 levels in regulatory T cells enhances immune suppression by driving early effector differentiation
    1
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    sciencedirect.com/science/article/pii/S2211124724010751
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    Sex-dependent effects in the aged melanoma tumor microenvironment influence invasion and resistance to targeted therapy
    1
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    sciencedirect.com/science/article/pii/S0092867424009048
  13. Aug 2024
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Feedforward cysteine regulation maintains melanoma differentiation state and limits metastatic spread
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    1. scibot 21 Aug 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11316253/
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    Thyroid hormone suppresses medulloblastoma progression through promoting terminal differentiation of tumor cells
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    1. scibot 21 Aug 2024
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    sciencedirect.com/science/article/pii/S1535610824002733
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    The fork protection complex promotes parental histone recycling and epigenetic memory
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    sciencedirect.com/science/article/pii/S0092867424007773
  17. Jul 2024
  18. www.sciencedirect.com www.sciencedirect.com
    The activity of early-life gene regulatory elements is hijacked in aging through pervasive AP-1-linked chromatin opening
    1
    1. scibot 19 Jul 2024
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    sciencedirect.com/science/article/pii/S1550413124002316
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    H3 K27M and EZHIP Impede H3K27-Methylation Spreading by Inhibiting Allosterically Stimulated PRC2
    1
    1. scibot 18 Jul 2024
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      DOI: 10.1016/j.molcel.2020.09.028

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    ncbi.nlm.nih.gov/pmc/articles/PMC7680438/
  20. Jun 2024
  21. link.springer.com link.springer.com
    Spatially resolved epigenome sequencing via Tn5 transposition and deterministic DNA barcoding in tissue
    1
    1. scibot 30 Jun 2024
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      DOI: 10.1038/s41596-024-01013-y

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    link.springer.com/article/10.1038/s41596-024-01013-y
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The TERT Promoter is Polycomb-Repressed in Neuroblastoma Cells with Long Telomeres
    1
    1. scibot 27 Jun 2024
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      DOI: 10.1158/2767-9764.CRC-22-0287

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  23. www.sciencedirect.com www.sciencedirect.com
    DOT1L maintains NK cell phenotype and function for optimal tumor control
    1
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    sciencedirect.com/science/article/pii/S2211124724006612
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    Lineage specification in glioblastoma is regulated by METTL7B
    1
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    sciencedirect.com/science/article/pii/S2211124724006375
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Defining cis-regulatory elements and transcription factors that control human cortical interneuron development
    1
    1. scibot 03 Jun 2024
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      DOI: 10.1016/j.isci.2024.109967

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    ncbi.nlm.nih.gov/pmc/articles/PMC11140214/
  26. May 2024
  27. www.sciencedirect.com www.sciencedirect.com
    Deletion of the mRNA endonuclease Regnase-1 promotes NK cell anti-tumor activity via OCT2-dependent transcription of Ifng
    2
    1. scibot 31 May 2024
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      DOI: 10.1016/j.immuni.2024.05.006

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    sciencedirect.com/science/article/pii/S1074761324002590
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    Enhanced ApcMin/+ adenoma formation after epithelial CUL4B deletion by recruitment of myeloid-derived suppressor cells
    1
    1. scibot 21 May 2024
      Cell Signaling Technology, Cat# 9733S

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    sciencedirect.com/science/article/pii/S1476558624000472
  29. 52.53.155.43 52.53.155.43
    2024.02.25.581951v1.full-html.html
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      DOI: 10.1038/nature12362

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    Identification of WNK1 as a therapeutic target to suppress IgH/MYC expression in multiple myeloma
    1
    1. scibot 09 May 2024
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    sciencedirect.com/science/article/pii/S2211124724005394
  31. Apr 2024
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Protein degradation of Lysine-specific demethylase 1 is mediated by Bre1 yet opposed by Lsd1-interacting lncRNAs during fly follicle development
    1
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  33. www.sciencedirect.com www.sciencedirect.com
    The Drosophila Hippo pathway transcription factor Scalloped and its co-factors alter each other’s chromatin binding dynamics and transcription in vivo
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  34. www.embopress.org www.embopress.org
    The growth factor EPIREGULIN promotes basal progenitor cell proliferation in the developing neocortex
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  35. rupress.org rupress.org
    Tunable DNMT1 degradation reveals DNMT1/DNMT3B synergy in DNA methylation and genome organization
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      DOI: 10.1083/jcb.202307026

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    rupress.org/jcb/article/223/4/e202307026/276570/Tunable-DNMT1-degradation-reveals-DNMT1-DNMT3B
  36. www.embopress.org www.embopress.org
    The growth factor EPIREGULIN promotes basal progenitor cell proliferation in the developing neocortex
    1
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  37. aacrjournals.org aacrjournals.org
    miR-217 regulates normal and tumor cell fate following induction of Endoplasmic Reticulum Stress
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      DOI: 10.1158/1541-7786.MCR-23-0676

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    aacrjournals.org/mcr/article/22/4/360/741846/miR-217-Regulates-Normal-and-Tumor-Cell-Fate
  38. www.sciencedirect.com www.sciencedirect.com
    Nucleation and spreading maintain Polycomb domains every cell cycle
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    H2AK119ub1 differentially fine-tunes gene expression by modulating canonical PRC1- and H1-dependent chromatin compaction
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  40. www.sciencedirect.com www.sciencedirect.com
    SP6 controls human cytotrophoblast fate decisions and trophoblast stem cell establishment by targeting MSX2 regulatory elements
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  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    EZH2 as a major histone methyltransferase in PDGF-BB-activated orbital fibroblast in the pathogenesis of Graves’ ophthalmopathy
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    ncbi.nlm.nih.gov/pmc/articles/PMC10994939/
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Select EZH2 inhibitors enhance viral mimicry effects of DNMT inhibition through a mechanism involving NFAT:AP-1 signaling
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      DOI: 10.1126/sciadv.adk4423

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  43. Mar 2024
  44. www.sciencedirect.com www.sciencedirect.com
    Histone lysine demethylase 4 family proteins maintain the transcriptional program and adrenergic cellular state of MYCN-amplified neuroblastoma
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      DOI: 10.1016/j.xcrm.2024.101468

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    sciencedirect.com/science/article/pii/S2666379124001149
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    Transcription elongation defects link oncogenic SF3B1 mutations to targetable alterations in chromatin landscape
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    Proteomic profiling reveals distinct phases to the restoration of chromatin following DNA replication
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  149. Nov 2022
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    XIST loss impairs mammary stem cell differentiation and increases tumorigenicity through Mediator hyperactivation
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    H3-K27M-mutant nucleosomes interact with MLL1 to shape the glioma epigenetic landscape
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    NSD1 mediates antagonism between SWI/SNF and polycomb complexes and is required for transcriptional activation upon EZH2 inhibition
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    KSHV episome tethering sites on host chromosomes and regulation of latency-lytic switch by CHD4
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  183. Apr 2022
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    The mitochondrial pyruvate carrier regulates memory T cell differentiation and antitumor function
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    Single-cell proteomics defines the cellular heterogeneity of localized prostate cancer
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    Linkage of methionine addiction, histone lysine hypermethylation, and malignancy
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  187. www.sciencedirect.com www.sciencedirect.com
    Promoter and enhancer RNAs regulate chromatin reorganization and activation of miR-10b/HOXD locus, and neoplastic transformation in glioma
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  188. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Maintenance of glutamine synthetase expression alleviates endotoxin-induced sepsis via alpha-ketoglutarate-mediated demethylation
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  189. Mar 2022
  190. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Thymocytes trigger self-antigen-controlling pathways in immature medullary thymic epithelial stages
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    The KRAS-G12D mutation induces Metabolic Vulnerability in B-cell Acute Lymphoblastic Leukemia
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  192. Feb 2022
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    Cellular plasticity upon proton irradiation determines tumor cell radiosensitivity
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    EBF1 nuclear repositioning instructs chromatin refolding to promote therapy resistance in T leukemic cells
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    The anti-aging protein Klotho affects early postnatal myogenesis by downregulating Jmjd3 and the canonical Wnt pathway
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    Substrate rigidity dictates colorectal tumorigenic cell stemness and metastasis via CRAD-dependent mechanotransduction
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    Activation-induced chromatin reorganization in neurons depends on HDAC1 activity
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    Epigenomic priming of immune genes implicates oligodendroglia in multiple sclerosis susceptibility
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    Gene silencing by EZH2 suppresses TGF-β activity within the decidua to avert pregnancy-adverse wound healing at the maternal-fetal interface
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  200. Jan 2022
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    PRC1 sustains the integrity of neural fate in the absence of PRC2 function
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  202. Dec 2021
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    Translational and post-translational control of human naïve versus primed pluripotency
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    TRACE generates fluorescent human reporter cell lines to characterize epigenetic pathways
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    KDM6B promotes activation of the oncogenic CDK4/6-pRB-E2F pathway by maintaining enhancer activity in MYCN-amplified neuroblastoma
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  206. Nov 2021
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    CUT&Tag-BS for simultaneous profiling of histone modification and DNA methylation with high efficiency and low cost
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      9733S

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    MTHFD2 is a metabolic checkpoint controlling effector and regulatory T cell fate and function
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    Histone H3.3 K27M and K36M mutations de-repress transposable elements through perturbation of antagonistic chromatin marks
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    Acute depletion of the ARID1A subunit of SWI/SNF complexes reveals distinct pathways for activation and repression of transcription
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  211. Oct 2021
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    Increased ACTL6A occupancy within mSWI/SNF chromatin remodelers drives human squamous cell carcinoma
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    NRF1 association with AUTS2-Polycomb mediates specific gene activation in the brain
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    A cis-acting structural variation at the ZNF558 locus controls a gene regulatory network in human brain development
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      DOI: 10.1016/j.stem.2021.09.008

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    Defining Proximity Proteomics of Histone Modifications by Antibody-mediated Protein A-APEX2 Labeling
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      DOI: 10.1016/j.gpb.2021.09.003

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  216. Sep 2021
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    Low folate induces abnormal neuronal maturation and DNA hypomethylation of neuronal differentiation-related genes in cultured mouse neural stem and progenitor cells
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  218. Aug 2021
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    Macrophage HIF-2α suppresses NLRP3 inflammasome activation and alleviates insulin resistance
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    Enhancement of gemcitabine efficacy by K73-03 via epigenetically regulation of miR-421/SPINK1 in gemcitabine resistant pancreatic cancer cells
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    Chromatin and transcription factor profiling in rare stem cell populations using CUT&Tag
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      DOI: 10.1016/j.xpro.2021.100751

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  222. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Quantitative control of noise in mammalian gene expression by dynamic histone regulation
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      DOI: 10.7554/eLife.65654

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    ncbi.nlm.nih.gov/pmc/articles/PMC8357418/
  223. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HNRNPM controls circRNA biogenesis and splicing fidelity to sustain cancer cell fitness
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