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258 Matching Annotations

Sep 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

STING nuclear partners contribute to innate immune signaling responses

1
1. scibot 22 Sep 2021
  
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  RRID:AB_2732796
  
  DOI: 10.1016/j.isci.2021.103055
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8436130/
Aug 2021
www.sciencedirect.com www.sciencedirect.com

Induced phase separation of mutant NF2 imprisons the cGAS-STING machinery to abrogate antitumor immunity

1
1. scibot 28 Aug 2021
  
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  RRID:AB_2732796
  
  DOI: 10.1016/j.molcel.2021.07.040
  
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sciencedirect.com/science/article/pii/S1097276521006249
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Targeting Pin1 renders pancreatic cancer eradicable by synergizing with immunochemotherapy

1
1. scibot 16 Aug 2021
  
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  RRID:AB_2732796
  
  DOI: 10.1016/j.cell.2021.07.020
  
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sciencedirect.com/science/article/pii/S0092867421008795
cancerres.aacrjournals.org cancerres.aacrjournals.org

SHP2-Mediated Inhibition of DNA Repair Contributes to cGAS–STING Activation and Chemotherapeutic Sensitivity in Colon Cancer

1
1. scibot 16 Aug 2021
  
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  RRID:AB_2732796
  
  DOI: 10.1158/0008-5472.CAN-20-3738
  
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cancerres.aacrjournals.org/content/81/12/3215
onlinelibrary.wiley.com onlinelibrary.wiley.com

Epigenetic Dysregulation Induces Translocation of Histone H3 into Cytoplasm

1
1. scibot 11 Aug 2021
  
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  RRID:AB_2732796
  
  DOI: 10.1002/advs.202100779
  
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onlinelibrary.wiley.com/doi/10.1002/advs.202100779
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Innate immune response orchestrates phosphoribosyl pyrophosphate synthetases to support DNA repair

1
1. scibot 03 Aug 2021
  
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  RRID:AB_2732796
  
  DOI: 10.1016/j.cmet.2021.07.009
  
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sciencedirect.com/science/article/pii/S1550413121003259
www.ncbi.nlm.nih.govhttp: www.ncbi.nlm.nih.govhttp:

Non-canonical Activation of the DNA Sensing Adaptor STING by ATM and IFI16 Mediates NF-κB Signaling after Nuclear DNA Damage

1
1. scibot 01 Aug 2021
  
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  RRID:AB_2732796
  
  DOI: 10.1016/j.molcel.2018.07.034
  
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ncbi.nlm.nih.govhttp://europepmc.org/articles/PMC6127031/
Jul 2021
www.nature.com www.nature.com

Tonic prime-boost of STING signalling mediates Niemann–Pick disease type C

1
1. scibot 31 Jul 2021
  
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  13647
  
  DOI: 10.1038/s41586-021-03762-2
  
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nature.com/articles/s41586-021-03762-2
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LSD1 Ablation Stimulates Anti-tumor Immunity and Enables Checkpoint Blockade

1
1. scibot 29 Jul 2021
  
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  RRID:AB_2732796
  
  DOI: 10.1016/j.cell.2018.05.052
  
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  RRID:AB_2732796 RRIDCUR:Unresolved RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S0092867418307153
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

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1. scibot 28 Jul 2021
  
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  RRID:AB_2732796
  
  DOI: 10.1016/j.molcel.2018.07.034
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6127031/
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Cell-autonomous inflammation of BRCA1-deficient ovarian cancers drives both tumor-intrinsic immunoreactivity and immune resistance via STING

1
1. scibot 23 Jul 2021
  
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  RRID:AB_2732796
  
  DOI: 10.1016/j.celrep.2021.109412
  
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sciencedirect.com/science/article/pii/S2211124721008251
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PARP7 negatively regulates the type I interferon response in cancer cells and its inhibition triggers antitumor immunity

1
1. scibot 23 Jul 2021
  
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  RRID:AB_2732796
  
  DOI: 10.1016/j.ccell.2021.06.018
  
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sciencedirect.com/science/article/pii/S1535610821003408
Jun 2021
clincancerres.aacrjournals.org clincancerres.aacrjournals.org

Mutations in the IFNγ-JAK-STAT pathway causing resistance to immune checkpoint inhibitors in melanoma increase sensitivity to oncolytic virus treatment.

1
1. scibot 29 Jun 2021
  
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  RRID:AB_2732796
  
  DOI: 10.1158/1078-0432.CCR-20-3365
  
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clincancerres.aacrjournals.org/content/27/12/3432
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DHX15 is required to control RNA virus-induced intestinal inflammation

1
1. scibot 23 Jun 2021
  
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  RRID:AB_2732796
  
  DOI: 10.1016/j.celrep.2021.109205
  
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sciencedirect.com/science/article/pii/S2211124721005544
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C9orf72 deficiency promotes microglial-mediated synaptic loss in aging and amyloid accumulation

1
1. scibot 16 Jun 2021
  
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  RRID:AB_2732796
  
  DOI: 10.1016/j.neuron.2021.05.020
  
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sciencedirect.com/science/article/pii/S0896627321003731
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Translation stress and collided ribosomes are co-activators of cGAS

1
1. scibot 10 Jun 2021
  
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  RRID:AB_2732796
  
  DOI: 10.1016/j.molcel.2021.05.018
  
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sciencedirect.com/science/article/pii/S1097276521004020
May 2021
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Dysbiosis exacerbates colitis by promoting ubiquitination and accumulation of the innate immune adaptor STING in myeloid cells

1
1. scibot 29 May 2021
  
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  RRID: 2732796
  
  DOI: 10.1016/j.immuni.2021.05.008
  
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sciencedirect.com/science/article/pii/S1074761321002144
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The inhibitory receptor TIM-3 limits activation of the cGAS-STING pathway in intra-tumoral dendritic cells by suppressing extracellular DNA uptake

1
1. scibot 12 May 2021
  
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  RRID:AB_2732796
  
  DOI: 10.1016/j.immuni.2021.04.019
  
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sciencedirect.com/science/article/pii/S1074761321001813
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BMI1 Inhibition Eliminates Residual Cancer Stem Cells after PD1 Blockade and Activates Antitumor Immunity to Prevent Metastasis and Relapse

1
1. scibot 09 May 2021
  
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  RRID:AB_2732796
  
  DOI: 10.1016/j.stem.2020.06.022
  
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sciencedirect.com/science/article/pii/S1934590920302897
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Targeting KDM4A epigenetically activates tumor-cell-intrinsic immunity by inducing DNA replication stress

1
1. scibot 08 May 2021
  
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  RRID:AB_2732796
  
  DOI: 10.1016/j.molcel.2021.02.038
  
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sciencedirect.com/science/article/pii/S1097276521001684
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SENP3 senses oxidative stress to facilitate STING-dependent dendritic cell antitumor function

1
1. scibot 08 May 2021
  
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  AB_2732796
  
  DOI: 10.1016/j.molcel.2020.12.024
  
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sciencedirect.com/science/article/pii/S109727652030945X
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LRRC8A:C/E Heteromeric Channels Are Ubiquitous Transporters of cGAMP

1
1. scibot 08 May 2021
  
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  RRID:AB_2732796
  
  DOI: 10.1016/j.molcel.2020.10.021
  
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sciencedirect.com/science/article/pii/S1097276520307280
Apr 2021
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Mutant p53 suppresses innate immune signaling to promote tumorigenesis

1
1. scibot 22 Apr 2021
  
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  RRID:AB_2732796
  
  DOI: 10.1016/j.ccell.2021.01.003
  
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  RRID:AB_2732796 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1535610821000416
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MLH1 Deficiency-Triggered DNA Hyperexcision by Exonuclease 1 Activates the cGAS-STING Pathway

1
1. scibot 22 Apr 2021
  
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  RRID:AB_2732796
  
  DOI: 10.1016/j.ccell.2020.11.004
  
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  RRID:AB_2732796 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1535610820305961
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A STING antagonist modulating the interaction with STIM1 blocks ER-to-Golgi trafficking and inhibits lupus pathology

1
1. scibot 07 Apr 2021
  
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  anti‐STING
  
  DOI: 10.1016/j.ebiom.2021.103314
  
  Resource: (Cell Signaling Technology Cat# 13647, RRID:AB_2732796)
  
  Curator: @Naa003
  
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  RRIDCUR:Missing RRID:AB_2732796
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sciencedirect.com/science/article/pii/S2352396421001079
Feb 2021
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DNA Sensing in Mismatch Repair-Deficient Tumor Cells Is Essential for Anti-tumor Immunity

1
1. scibot 28 Feb 2021
  
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  RRID:AB_2732796
  
  DOI: 10.1016/j.ccell.2020.11.006
  
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sciencedirect.com/science/article/pii/S1535610820305985
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FBXO44 promotes DNA replication-coupled repetitive element silencing in cancer cells

1
1. scibot 27 Feb 2021
  
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  RRID:AB_2732796
  
  DOI: 10.1016/j.cell.2020.11.042
  
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sciencedirect.com/science/article/pii/S0092867420316147
www.mdpi.com www.mdpi.com

Signal Transducer and Activator of Transcription 3 (STAT3) Suppresses STAT1/Interferon Signaling Pathway and Inflammation in Senescent Preadipocytes

1
1. scibot 27 Feb 2021
  
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  RRID:AB_2732796
  
  DOI: 10.3390/antiox10020334
  
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  RRID:AB_2732796 RRIDCUR:Validated
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mdpi.com/2076-3921/10/2/334
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Disruption of DNA polymerase ζ engages an innate immune response

1
1. scibot 25 Feb 2021
  
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  RRID:AB_2732796
  
  DOI: 10.1016/j.celrep.2021.108775
  
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  RRIDCUR:Validated RRID:AB_2732796
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sciencedirect.com/science/article/pii/S2211124721000887
Dec 2020
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Modular Architecture of the STING C-Terminal Tail Allows Interferon and NF-κB Signaling Adaptation

1
1. scibot 17 Dec 2020
  
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  RRID:AB_2732796
  
  DOI: 10.1016/j.celrep.2019.03.098
  
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  Curator: @evieth
  
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  RRIDCUR:Validated RRID:AB_2732796
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ncbi.nlm.nih.gov/pmc/articles/PMC7733315/
Oct 2020
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

TDP-43 Triggers Mitochondrial DNA Release via mPTP to Activate cGAS/STING in ALS

1
1. scibot 10 Oct 2020
  
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  RRID:AB_2732796
  
  DOI: 10.1016/j.cell.2020.09.020
  
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  RRIDCUR:Validated RRID:AB_2732796
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pubmed.ncbi.nlm.nih.gov/33031745/
Sep 2020
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mtDNA Activates cGAS Signaling and Suppresses the YAP-Mediated Endothelial Cell Proliferation Program to Promote Inflammatory Injury

1
1. scibot 23 Sep 2020
  
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  RRID:AB_2732796
  
  DOI: 10.1016/j.immuni.2020.02.002
  
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  RRID:AB_2732796 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S107476132030073X
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TBK1 and IKKε Act Redundantly to Mediate STING-Induced NF-κB Responses in Myeloid Cells

1
1. scibot 16 Sep 2020
  
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  RRID:AB_2732796
  
  DOI: 10.1016/j.celrep.2020.03.056
  
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  Curator: @ethanbadger
  
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  RRIDCUR:Validated RRID:AB_2732796
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sciencedirect.com/science/article/pii/S2211124720303703
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Transfer of cGAMP into Bystander Cells via LRRC8 Volume-Regulated Anion Channels Augments STING-Mediated Interferon Responses and Anti-viral Immunity

1
1. scibot 16 Sep 2020
  
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  RRID:AB_2732796
  
  DOI: 10.1016/j.immuni.2020.03.016
  
  Resource: (Cell Signaling Technology Cat# 13647, RRID:AB_2732796)
  
  Curator: @ethanbadger
  
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  RRIDCUR:Validated RRID:AB_2732796
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sciencedirect.com/science/article/pii/S1074761320301291
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Blockade of the Phagocytic Receptor MerTK on Tumor-Associated Macrophages Enhances P2X7R-Dependent STING Activation by Tumor-Derived cGAMP

1
1. scibot 15 Sep 2020
  
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  RRID:AB_2732796
  
  DOI: 10.1016/j.immuni.2020.01.014
  
  Resource: (Cell Signaling Technology Cat# 13647, RRID:AB_2732796)
  
  Curator: @ethanbadger
  
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Comprehensive Molecular Characterization Identifies Distinct Genomic and Immune Hallmarks of Renal Medullary Carcinoma

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  DOI: 10.1016/j.ccell.2020.04.002
  
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The Cyclopeptide Astin C Specifically Inhibits the Innate Immune CDN Sensor STING

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  DOI: 10.1016/j.celrep.2018.11.097
  
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C9orf72 in myeloid cells suppresses STING-induced inflammation

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  STING
  
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Single-Chromosomal Gains Can Function as Metastasis Suppressors and Promoters in Colon Cancer

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  DOI: 10.1016/j.devcel.2020.01.034
  
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Mitochondrial Damage Causes Inflammation via cGAS-STING Signaling in Acute Kidney Injury

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IFI16 Targets the Transcription Factor Sp1 to Suppress HIV-1 Transcription and Latency Reactivation

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  DOI: 10.1016/j.chom.2019.05.002
  
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The Cytoplasmic DNA Sensor cGAS Promotes Mitotic Cell Death

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  DOI: 10.1016/j.cell.2019.05.035
  
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STING Polymer Structure Reveals Mechanisms for Activation, Hyperactivation, and Inhibition

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Molecular Profiling and Functional Analysis of Macrophage-Derived Tumor Extracellular Vesicles

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CDK7 Inhibition Potentiates Genome Instability Triggering Anti-tumor Immunity in Small Cell Lung Cancer

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  DOI: 10.1016/j.ccell.2019.11.003
  
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STING-Mediated IFI16 Degradation Negatively Controls Type I Interferon Production

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Cancer-Cell-Intrinsic cGAS Expression Mediates Tumor Immunogenicity

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Untitled document

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  DOI: 10.1016/j.celrep.2018.11.097
  
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SLC19A1 Is an Importer of the Immunotransmitter cGAMP

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  DOI: 10.1016/j.molcel.2019.05.006
  
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  DOI: 10.1016/j.celrep.2019.03.098
  
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  DOI: 10.1016/j.celrep.2019.01.105
  
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  DOI: 10.1016/j.celrep.2018.11.094
  
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Interleukin-1β Induces mtDNA Release to Activate Innate Immune Signaling via cGAS-STING

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  DOI: 10.1016/j.molcel.2019.02.038
  
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Immune Checkpoint Inhibition Overcomes ADCP-Induced Immunosuppression by Macrophages

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  13647
  
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NONO Detects the Nuclear HIV Capsid to Promote cGAS-Mediated Innate Immune Activation

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Non-canonical Activation of the DNA Sensing Adaptor STING by ATM and IFI16 Mediates NF-κB Signaling after Nuclear DNA Damage

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ncbi.nlm.nih.govhttp://europepmc.org/articles/PMC6127031/
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Gasdermin D Restrains Type I Interferon Response to Cytosolic DNA by Disrupting Ionic Homeostasis

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Untitled document

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