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Innate immune sensing of Z-nucleic acids by ZBP1-RIPK1 axis drives neuroinflammation in Alzheimer’s disease

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1. scibot 03 Sep 2025
  
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  DOI: 10.1016/j.immuni.2025.07.024
  
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sciencedirect.com/science/article/pii/S1074761325003334
Jul 2025
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Interferon-driven CAF reprogramming augments immunogenic response to neoadjuvant radiotherapy in colorectal cancer

1
1. scibot 29 Jul 2025
  
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  DOI: 10.1016/j.xcrm.2025.102251
  
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sciencedirect.com/science/article/pii/S2666379125003246
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Ce6 derivative photodynamic therapy triggers PANoptosis and enhances antitumor immunity with LAG3 blockade in cutaneous squamous cell carcinoma

1
1. scibot 16 Jul 2025
  
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  RRID:AB_2732796
  
  DOI: 10.1016/j.xcrm.2025.102239
  
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sciencedirect.com/science/article/pii/S266637912500312X
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A fluorescent STING ligand sensor for high-throughput screening of compounds that can enhance tumor immunotherapy

1
1. scibot 16 Jul 2025
  
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  RRID:AB_2732796
  
  DOI: 10.1016/j.crmeth.2025.101106
  
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sciencedirect.com/science/article/pii/S2667237525001420
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Riluzole Enhancing anti-PD-1 Efficacy by Activating cGAS/STING Signaling in Colorectal Cancer

1
1. scibot 04 Jul 2025
  
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  RRID:AB_2732796
  
  DOI: 10.1158/1535-7163.MCT-24-0289
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11695182/
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MLKL activates the cGAS-STING pathway by releasing mitochondrial DNA upon necroptosis induction

1
1. scibot 03 Jul 2025
  
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  RRID:AB_2732796
  
  DOI: 10.1016/j.molcel.2025.06.005
  
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sciencedirect.com/science/article/pii/S1097276525005052
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Augment proteasome inhibitor efficacy activates CD8+ T cell-mediated antitumor immunity in breast cancer

1
1. scibot 02 Jul 2025
  
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  RRID:AB_2732796
  
  DOI: 10.1016/j.xcrm.2025.102211
  
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sciencedirect.com/science/article/pii/S2666379125002848
Jun 2025
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A guide to selecting high-performing antibodies for STING1 (Uniprot ID: Q86WV6) for use in western blot, immunoprecipitation, and immunofluorescence

1
1. scibot 25 Jun 2025
  
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  AB_2732796
  
  DOI: 10.12688/f1000research.155929.2
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12175898/
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Downregulation of cGAS/STING expression in tumor cells by cancer-associated fibroblasts in colorectal cancer

1
1. scibot 04 Jun 2025
  
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  RRID:AB_2732796
  
  DOI: 10.1038/s41598-025-03924-6
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12127464/
May 2025
www.cell.com www.cell.com

KSHV miRNAs target STING to evade innate immunity and facilitate KSHV lytic reactivation from latency

1
1. scibot 29 May 2025
  
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  RRID:AB_2732796
  
  DOI: 10.1016/j.celrep.2025.115741
  
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cell.com/cell-reports/fulltext/S2211-1247(25)00512-1
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PUS10-induced tRNA fragmentation impacts retrotransposon-driven inflammation

1
1. scibot 22 May 2025
  
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  RRID:AB_2732796
  
  DOI: 10.1016/j.celrep.2025.115735
  
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sciencedirect.com/science/article/pii/S2211124725005066
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Reducing Dietary Protein Enhances the Antitumor Effects of Chemotherapy through Immune-Mediated Mechanisms

1
1. scibot 20 May 2025
  
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  RRID:AB_2732796
  
  DOI: 10.1158/1535-7163.MCT-24-0545
  
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pmc.ncbi.nlm.nih.gov/articles/PMC7617599/
Apr 2025
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Carvedilol sensitizes chemotherapy by targeting STING to boost anti-tumor immunity

1
1. scibot 19 Apr 2025
  
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  RRID:AB_2732796
  
  DOI: 10.1016/j.celrep.2025.115572
  
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sciencedirect.com/science/article/pii/S2211124725003432
52.53.155.43 52.53.155.43

1-s2.0-S2589004225006522-main-html.html

1
1. scibot 10 Apr 2025
  
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  AB_2732796
  
  DOI: 10.1016/j.isci.2025.112391
  
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52.53.155.43/65da5ba6fe747fbc09139b682088b351a925dfd8/1-s2.0-S2589004225006522-main-html.html
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Mitochondrial DNA released by senescent tumor cells enhances PMN-MDSC-driven immunosuppression through the cGAS-STING pathway

1
1. scibot 09 Apr 2025
  
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  RRID:AB_2732796
  
  DOI: 10.1016/j.immuni.2025.03.005
  
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sciencedirect.com/science/article/pii/S1074761325001244
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STING mediates lysosomal quality control and recovery through its proton channel function and TFEB activation in lysosomal storage disorders

1
1. scibot 05 Apr 2025
  
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  RRID:AB_2732796
  
  DOI: 10.1016/j.molcel.2025.03.008
  
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sciencedirect.com/science/article/pii/S1097276525002011
52.53.155.43 52.53.155.43

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1
1. scibot 04 Apr 2025
  
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  RRID:AB_2732796
  
  DOI: 10.1158/2326-6066.cir-24-0834
  
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52.53.155.43/b8eb1cd1446295bdd52d11650093cdf439d34361/PDF-html.html
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Cancer-cell-derived cGAMP limits the activity of tumor-associated CD8+ T cells

1
1. scibot 03 Apr 2025
  
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  RRID:AB_2732796
  
  DOI: 10.1016/j.celrep.2025.115510
  
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sciencedirect.com/science/article/pii/S2211124725002815
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Interferon-Inducible ADAR1 p150 Is Essential for the Survival of Oral Squamous Cell Carcinoma

1
1. scibot 01 Apr 2025
  
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  RRID:AB_2732796
  
  DOI: 10.1002/mc.23910
  
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onlinelibrary.wiley.com/doi/10.1002/mc.23910
Mar 2025
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The actin and microtubule network regulator WHAMM is identified as a key kidney disease risk gene

1
1. scibot 29 Mar 2025
  
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  RRID:AB_2732796
  
  DOI: 10.1016/j.celrep.2025.115462
  
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sciencedirect.com/science/article/pii/S2211124725002335
52.53.155.43 52.53.155.43

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1
1. scibot 24 Mar 2025
  
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  RRID:AB_2732796
  
  DOI: 10.1158/1535-7163.mct-24-0545
  
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52.53.155.43/089c935c8b8375c73eca3bfe64a1d2170a0cdb88/PDF-html.html
Feb 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

PARP Inhibitors Differentially Regulate Immune Responses in Distinct Genetic Backgrounds of High-Grade Serous Tubo-Ovarian Carcinoma

1
1. scibot 27 Feb 2025
  
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  RRID:AB_2732796
  
  DOI: 10.1158/2767-9764.CRC-24-0515
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11836641/
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RBM43 controls PGC1α translation and a PGC1α-STING signaling axis

1
1. scibot 20 Feb 2025
  
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  RRID:AB_2732796
  
  DOI: 10.1016/j.cmet.2025.01.013
  
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sciencedirect.com/science/article/pii/S1550413125000130
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Nanoparticle delivery of innate immune agonists combined with senescence-inducing agents promotes T cell control of pancreatic cancer

1
1. scibot 13 Feb 2025
  
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  RRID:AB_2732796
  
  DOI: 10.1126/scitranslmed.adj9366
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11811823/
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ArfGAP2 promotes STING proton channel activity, cytokine transit, and autoinflammation

1
1. scibot 13 Feb 2025
  
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  RRID:AB_2732796
  
  DOI: 10.1016/j.cell.2025.01.027
  
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sciencedirect.com/science/article/pii/S0092867425000960
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TRIM65 regulates innate immune signaling by enhancing K6-linked ubiquitination of IRF3 and its chromatin recruitment

7
1. scibot 07 Feb 2025
  
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  RRID:AB_2732796
  
  DOI: 10.1016/j.celrep.2024.114960
  
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  Curator: @scibot
  
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2. scibot 06 Feb 2025
  
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  RRID:AB_2732796
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2732796
3. scibot 05 Feb 2025
  
  in Public
  
  RRID:AB_2732796
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2732796
4. scibot 04 Feb 2025
  
  in Public
  
  RRID:AB_2732796
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2732796
5. scibot 03 Feb 2025
  
  in Public
  
  RRID:AB_2732796
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2732796
6. scibot 02 Feb 2025
  
  in Public
  
  RRID:AB_2732796
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2732796
7. scibot 01 Feb 2025
  
  in Public
  
  RRID:AB_2732796
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
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sciencedirect.com/science/article/pii/S2211124724013111
52.53.155.43 52.53.155.43

Toxicity of extracellular cGAMP and its analogs to T cells is due to SLC7A1-mediated import

1
1. scibot 06 Feb 2025
  
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  AB_2732796
  
  DOI: 10.1101/2024.09.21.614248
  
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52.53.155.43/5ae47209b7006eb85d3adbe5cd2f83306ecd19fd/2024.09.21.614248.full-html.html
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An oral tricyclic STING agonist suppresses tumor growth through remodeling of the immune microenvironment

1
1. scibot 04 Feb 2025
  
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  RRID:AB_2732796
  
  DOI: 10.1016/j.chembiol.2025.01.004
  
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sciencedirect.com/science/article/pii/S2451945625000042
Jan 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Cell-free assays reveal that the HIV-1 capsid protects reverse transcripts from cGAS immune sensing

1
1. scibot 31 Jan 2025
  
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  RRID:AB_2732796
  
  DOI: 10.1371/journal.ppat.1012206
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11793794/
52.53.155.43 52.53.155.43

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1. scibot 31 Jan 2025
  
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  RRID:AB_2732796
  
  DOI: 10.1371/journal.ppat.1012206
  
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52.53.155.43/c74348c45bccaf197fb20d31d8b35ab413c8424c/PDF-html.html
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TRIM65 regulates innate immune signaling by enhancing K6-linked ubiquitination of IRF3 and its chromatin recruitment

31
1. scibot 31 Jan 2025
  
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  RRID:AB_2732796
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2732796
2. scibot 30 Jan 2025
  
  in Public
  
  RRID:AB_2732796
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2732796
3. scibot 29 Jan 2025
  
  in Public
  
  RRID:AB_2732796
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2732796
4. scibot 28 Jan 2025
  
  in Public
  
  RRID:AB_2732796
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2732796
5. scibot 27 Jan 2025
  
  in Public
  
  RRID:AB_2732796
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2732796
6. scibot 26 Jan 2025
  
  in Public
  
  RRID:AB_2732796
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2732796
7. scibot 25 Jan 2025
  
  in Public
  
  RRID:AB_2732796
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2732796
8. scibot 24 Jan 2025
  
  in Public
  
  RRID:AB_2732796
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2732796
9. scibot 23 Jan 2025
  
  in Public
  
  RRID:AB_2732796
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2732796
10. scibot 22 Jan 2025
  
  in Public
  
  RRID:AB_2732796
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2732796
11. scibot 21 Jan 2025
  
  in Public
  
  RRID:AB_2732796
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2732796
12. scibot 20 Jan 2025
  
  in Public
  
  RRID:AB_2732796
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2732796
13. scibot 19 Jan 2025
  
  in Public
  
  RRID:AB_2732796
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2732796
14. scibot 18 Jan 2025
  
  in Public
  
  RRID:AB_2732796
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2732796
15. scibot 17 Jan 2025
  
  in Public
  
  RRID:AB_2732796
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2732796
16. scibot 16 Jan 2025
  
  in Public
  
  RRID:AB_2732796
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2732796
17. scibot 15 Jan 2025
  
  in Public
  
  RRID:AB_2732796
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2732796
18. scibot 14 Jan 2025
  
  in Public
  
  RRID:AB_2732796
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2732796
19. scibot 13 Jan 2025
  
  in Public
  
  RRID:AB_2732796
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2732796
20. scibot 12 Jan 2025
  
  in Public
  
  RRID:AB_2732796
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2732796
21. scibot 11 Jan 2025
  
  in Public
  
  RRID:AB_2732796
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2732796
22. scibot 10 Jan 2025
  
  in Public
  
  RRID:AB_2732796
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2732796
23. scibot 09 Jan 2025
  
  in Public
  
  RRID:AB_2732796
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2732796
24. scibot 08 Jan 2025
  
  in Public
  
  RRID:AB_2732796
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2732796
25. scibot 07 Jan 2025
  
  in Public
  
  RRID:AB_2732796
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2732796
26. scibot 06 Jan 2025
  
  in Public
  
  RRID:AB_2732796
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2732796
27. scibot 05 Jan 2025
  
  in Public
  
  RRID:AB_2732796
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2732796
28. scibot 04 Jan 2025
  
  in Public
  
  RRID:AB_2732796
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2732796
29. scibot 03 Jan 2025
  
  in Public
  
  RRID:AB_2732796
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2732796
30. scibot 02 Jan 2025
  
  in Public
  
  RRID:AB_2732796
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2732796
31. scibot 01 Jan 2025
  
  in Public
  
  RRID:AB_2732796
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2732796
Visit annotations in context

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URL

sciencedirect.com/science/article/pii/S2211124724013111
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Structures of ATP-binding cassette transporter ABCC1 reveal the molecular basis of cyclic dinucleotide cGAMP export

1
1. scibot 07 Jan 2025
  
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  RRID:AB_2732796
  
  DOI: 10.1016/j.immuni.2024.12.002
  
  Resource: (Cell Signaling Technology Cat# 13647, RRID:AB_2732796)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2732796
  
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URL

sciencedirect.com/science/article/pii/S1074761324005661
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

BPS Publications

1
1. scibot 05 Jan 2025
  
  in Public
  
  RRID:AB_2732796
  
  DOI: 10.1111/bph.17425
  
  Resource: (Cell Signaling Technology Cat# 13647, RRID:AB_2732796)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2732796
  
  What is this?
  
  RRID:AB_2732796
Visit annotations in context

Tags

RRID:AB_2732796

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scibot

URL

bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.17425
Dec 2024
www.sciencedirect.com www.sciencedirect.com

TRIM65 regulates innate immune signaling by enhancing K6-linked ubiquitination of IRF3 and its chromatin recruitment

31
1. scibot 31 Dec 2024
  
  in Public
  
  RRID:AB_2732796
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2732796
2. scibot 30 Dec 2024
  
  in Public
  
  RRID:AB_2732796
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2732796
3. scibot 29 Dec 2024
  
  in Public
  
  RRID:AB_2732796
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2732796
4. scibot 28 Dec 2024
  
  in Public
  
  RRID:AB_2732796
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2732796
5. scibot 27 Dec 2024
  
  in Public
  
  RRID:AB_2732796
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2732796
6. scibot 26 Dec 2024
  
  in Public
  
  RRID:AB_2732796
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2732796
7. scibot 25 Dec 2024
  
  in Public
  
  RRID:AB_2732796
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2732796
8. scibot 24 Dec 2024
  
  in Public
  
  RRID:AB_2732796
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2732796
9. scibot 23 Dec 2024
  
  in Public
  
  RRID:AB_2732796
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2732796
10. scibot 22 Dec 2024
  
  in Public
  
  RRID:AB_2732796
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2732796
11. scibot 21 Dec 2024
  
  in Public
  
  RRID:AB_2732796
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2732796
12. scibot 20 Dec 2024
  
  in Public
  
  RRID:AB_2732796
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2732796
13. scibot 19 Dec 2024
  
  in Public
  
  RRID:AB_2732796
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2732796
14. scibot 18 Dec 2024
  
  in Public
  
  RRID:AB_2732796
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2732796
15. scibot 17 Dec 2024
  
  in Public
  
  RRID:AB_2732796
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2732796
16. scibot 16 Dec 2024
  
  in Public
  
  RRID:AB_2732796
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2732796
17. scibot 15 Dec 2024
  
  in Public
  
  RRID:AB_2732796
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2732796
18. scibot 14 Dec 2024
  
  in Public
  
  RRID:AB_2732796
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2732796
19. scibot 13 Dec 2024
  
  in Public
  
  RRID:AB_2732796
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2732796
20. scibot 12 Dec 2024
  
  in Public
  
  RRID:AB_2732796
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2732796
21. scibot 11 Dec 2024
  
  in Public
  
  RRID:AB_2732796
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2732796
22. scibot 10 Dec 2024
  
  in Public
  
  RRID:AB_2732796
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2732796
23. scibot 09 Dec 2024
  
  in Public
  
  RRID:AB_2732796
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2732796
24. scibot 08 Dec 2024
  
  in Public
  
  RRID:AB_2732796
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2732796
25. scibot 07 Dec 2024
  
  in Public
  
  RRID:AB_2732796
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2732796
26. scibot 06 Dec 2024
  
  in Public
  
  RRID:AB_2732796
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2732796
27. scibot 05 Dec 2024
  
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  RRID:AB_2732796
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2732796
28. scibot 04 Dec 2024
  
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  RRID:AB_2732796
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2732796
29. scibot 03 Dec 2024
  
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  RRID:AB_2732796
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2732796
30. scibot 02 Dec 2024
  
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  RRID:AB_2732796
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_2732796
31. scibot 01 Dec 2024
  
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  RRID:AB_2732796
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
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The N-degron pathway mediates the autophagic degradation of cytosolic mitochondrial DNA during sterile innate immune responses

1
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  RRID:AB_2732796
  
  DOI: 10.1016/j.celrep.2024.115094
  
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Classification and functional characterization of regulators of intracellular STING trafficking identified by genome-wide optical pooled screening

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TRIM65 regulates innate immune signaling by enhancing K6-linked ubiquitination of IRF3 and its chromatin recruitment

2
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  RRID:AB_2732796
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Targeting Catechol-O-Methyltransferase Induces Mitochondrial Dysfunction and Enhances the Efficacy of Radiotherapy in Glioma

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Antagonistic roles of cGAS/STING signaling in colorectal cancer chemotherapy

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  DOI: 10.3389/fonc.2024.1441935
  
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Type I IFN drives unconventional IL-1β secretion in lupus monocytes

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Disruption of cellular plasticity by repeat RNAs in human pancreatic cancer

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Alzheimer’s disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy model

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IKKɛ induces STING non-IFN immune responses via a mechanism analogous to TBK1

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Cell Cycle Checkpoints Cooperate to Suppress DNA- and RNA-Associated Molecular Pattern Recognition and Anti-Tumor Immune Responses

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Targeting EGLN2/PHD1 protects motor neurons and normalizes the astrocytic interferon response

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Histone chaperone HIRA, promyelocytic leukemia protein, and p62/SQSTM1 coordinate to regulate inflammation during cell senescence

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Structural analysis of RIG-I-like receptors reveals ancient rules of engagement between diverse RNA helicases and TRIM ubiquitin ligases

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  Rabbit anti-STING
  
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The V-ATPase/ATG16L1 axis is controlled by the V1H subunit

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VHL loss enhances antitumor immunity by activating the anti-viral DNA-sensing pathway

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Mitochondrial DNA-boosted dendritic cell-based nanovaccination triggers antitumor immunity in lung and pancreatic cancers

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STING orchestrates the neuronal inflammatory stress response in multiple sclerosis

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The exonuclease TREX1 constitutes an innate immune checkpoint limiting cGAS/STING-mediated antitumor immunity

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Pervasive nuclear envelope ruptures precede ECM signaling and disease onset without activating cGAS-STING in Lamin-cardiomyopathy mice

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cir-23-1078-html.html

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Development of nitroalkene-based inhibitors to target STING-dependent inflammation

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Micronuclei induced by radiation, replication stress, or chromosome segregation errors do not activate cGAS-STING

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ARID1A suppresses R-loop-mediated STING-type I interferon pathway activation of anti-tumor immunity

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Alzheimer's disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy model

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Intratumoral delivery of the chitin-derived C100 adjuvant promotes robust STING, IFNAR, and CD8+ T cell-dependent anti-tumor immunity

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Putting the STING back into BH3-mimetic drugs for TP53-mutant blood cancers

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Endothelial cell expression of a STING gain-of-function mutation initiates pulmonary lymphocytic infiltration

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HERC5-catalyzed ISGylation potentiates cGAS-mediated innate immunity

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The HIF transcription network exerts innate antiviral activity in neurons and limits brain inflammation

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DNA-PKcs is required for cGAS/STING-dependent viral DNA sensing in human cells

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  DOI: 10.1016/j.isci.2023.108760
  
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Vinorelbine causes a neuropathic pain-like state in mice via STING and MNK1 signaling associated with type I interferon induction.

1
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Interferon-stimulated neutrophils as a predictor of immunotherapy response

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Phage anti-CBASS protein simultaneously sequesters cyclic trinucleotides and dinucleotides

1
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SIX4 Controls Anti-PD-1 Efficacy by Regulating STING Expression

1
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Nuclear localization of STING1 competes with canonical signaling to activate AHR for commensal and intestinal homeostasis

1
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HRS mediates tumor immune evasion by regulating proteostasis-associated interferon pathway activation

1
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Adavosertib Enhances Antitumor Activity of Trastuzumab Deruxtecan in HER2-Expressing Cancers

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Regulation of STING activity in DNA sensing by ISG15 modification

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Blocking oligomerization is the most viable strategy to inhibit STING

1
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Effector memory T cells induce innate inflammation by triggering DNA damage and a non-canonical STING pathway in dendritic cells

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Mechanotransduction in response to ECM stiffening impairs cGAS immune signaling in tumor cells

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ccr-23-0103-html.html

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Spinal TAOK2 contributes to neuropathic pain via cGAS-STING activation in rats

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STING signaling promotes NK cell antitumor immunity and maintains a reservoir of TCF-1+ NK cells

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Aug 2023
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ccr-23-0103-html.html

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STING-IRG1 inhibits liver metastasis of colorectal cancer by regulating the polarization of tumor-associated macrophages

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Phage anti-CBASS protein simultaneously sequesters cyclic trinucleotides and dinucleotides

1
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ccr-23-0103-html.html

1
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Vinorelbine causes a neuropathic pain-like state in mice via STING and MNK1 signaling associated with type I interferon induction.

1
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Jun 2023
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The nucleotide receptor STING translocates to the phagosomes to negatively regulate anti-fungal immunity

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Methionine restriction promotes cGAS activation and chromatin untethering through demethylation to enhance antitumor immunity

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Cancer cell-autonomous cGAS-STING response confers drug resistance

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May 2023
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Exhaustion-associated cholesterol deficiency dampens the cytotoxic arm of antitumor immunity

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Context-dependent activation of STING-interferon signaling by CD11b agonists enhances anti-tumor immunity

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Human papillomavirus E5 suppresses immunity via inhibition of the immunoproteasome and STING pathway

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Apr 2023
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Innate immune pathway modulator screen identifies STING pathway activation as a strategy to inhibit multiple families of arbo and respiratory viruses

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Glutamylation of an HIV-1 protein inhibits the immune response by hijacking STING

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The mechanism of STING autoinhibition and activation

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ER-localized JmjC domain-containing protein JMJD8 targets STING to promote immune evasion and tumor growth in breast cancer

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Mar 2023
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STING activation in platelets aggravates septic thrombosis by enhancing platelet activation and granule secretion

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Saturated fatty acids dampen the immunogenicity of cancer by suppressing STING

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Leaked genomic and mitochondrial DNA contribute to the host response to noroviruses in a STING-dependent manner

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  DOI: 10.1016/j.celrep.2023.112179
  
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The ubiquitin E3 ligase TRIM10 promotes STING aggregation and activation in the Golgi apparatus

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  DOI: 10.1016/j.celrep.2023.112306
  
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NF-κB activation enhances STING signaling by altering microtubule-mediated STING trafficking

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  DOI: 10.1016/j.celrep.2023.112185
  
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Feb 2023
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Preclinical evaluation of tolvaptan and salsalate combination therapy in a Pkd1-mouse model

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  DOI: 10.3389/fmolb.2023.1058825
  
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Cytosolic DNA sensing by cGAS/STING promotes TRPV2-mediated Ca2+ release to protect stressed replication forks

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DNA damage repair kinase DNA-PK and cGAS synergize to induce cancer-related inflammation in glioblastoma

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The Golgi-resident protein ACBD3 concentrates STING at ER-Golgi contact sites to drive export from the ER

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Structurally distinct PARP7 inhibitors provide new insights into the function of PARP7 in regulating nucleic acid-sensing and IFN-β signaling

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Interferon-dependent SLC14A1+ cancer-associated fibroblasts promote cancer stemness via WNT5A in bladder cancer

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FEBS Press

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Driving axon regeneration by orchestrating neuronal and non-neuronal innate immune responses via the IFNγ-cGAS-STING axis

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Manganese enhances DNA- or RNA-mediated innate immune response by inducing phosphorylation of TANK-binding kinase 1

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Activation of cGAS-STING pathway – A possible cause of myofiber atrophy/necrosis in dermatomyositis and immune-mediated necrotizing myopathy

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ABCC1 transporter exports the immunostimulatory cyclic dinucleotide cGAMP

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Varicella‐Zoster virus ORF9 is an antagonist of the DNA sensor cGAS

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Replication stress triggered by nucleotide pool imbalance drives DNA damage and cGAS-STING pathway activation in NAFLD

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cGAS and DDX41-STING mediated intrinsic immunity spreads intercellularly to promote neuroinflammation in SOD1 ALS model

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The SETDB1–TRIM28 complex suppresses antitumor immunity

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LL-37 transports immunoreactive cGAMP to activate STING signaling and enhance interferon-mediated host antiviral immunity

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DDX41 is required for cGAS-STING activation against DNA virus infection

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STING is an intrinsic checkpoint inhibitor that restrains the TH17 cell pathogenic program

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DNA damage promotes HLA class I presentation by stimulating a pioneer round of translation-associated antigen production

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WEE1 inhibition enhances the antitumor immune response to PD-L1 blockade by the concomitant activation of STING and STAT1 pathways in SCLC

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Protocol to induce and assess cGAS-STING pathway activation in vitro

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The gut microbiota prime systemic antiviral immunity via the cGAS-STING-IFN-I axis

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The interplay between BAX and BAK tunes apoptotic pore growth to control mitochondrial-DNA-mediated inflammation

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MEK inhibition overcomes chemoimmunotherapy resistance by inducing CXCL10 in cancer cells

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Reprogramming of nucleotide metabolism by interferon confers dependence on the replication stress response pathway in pancreatic cancer cells

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STING orchestrates the crosstalk between polyunsaturated fatty acid metabolism and inflammatory responses

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IFI16 inhibits DNA repair that potentiates type-I interferon-induced antitumor effects in triple negative breast cancer

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BPS Publications

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TNF leads to mtDNA release and cGAS/STING-dependent interferon responses that support inflammatory arthritis

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APOL1 risk variants in individuals of African genetic ancestry drive endothelial cell defects that exacerbate sepsis

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CX-5461 Treatment Leads to Cytosolic DNA-Mediated STING Activation in Ovarian Cancer

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PKCλ/ι inhibition activates an ULK2-mediated interferon response to repress tumorigenesis

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