697 Matching Annotations
  1. Sep 2022
  2. www.sciencedirect.com www.sciencedirect.com
    SMN controls neuromuscular junction integrity through U7 snRNP
    1
    1. scibot 21 Sep 2022
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      DOI: 10.1016/j.celrep.2022.111393

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    sciencedirect.com/science/article/pii/S221112472201230X
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    Heterologous reporter expression in the planarian Schmidtea mediterranea through somatic mRNA transfection
    1
    1. scibot 21 Sep 2022
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      DOI: 10.1016/j.crmeth.2022.100298

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    sciencedirect.com/science/article/pii/S2667237522001801
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    Developmental and housekeeping transcriptional programs in Drosophila require distinct chromatin remodelers
    1
    1. scibot 16 Sep 2022
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      DOI: 10.1016/j.molcel.2022.08.019

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    sciencedirect.com/science/article/pii/S1097276522008085
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    Runx2 regulates chromatin accessibility to direct the osteoblast program at neonatal stages
    1
    1. scibot 08 Sep 2022
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      DOI: 10.1016/j.celrep.2022.111315

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    sciencedirect.com/science/article/pii/S2211124722011391
  6. Aug 2022
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    The Il6 -39kb enhancer containing clustered GATA2- and PU.1- binding sites is essential for Il6 expression in murine mast cells
    1
    1. scibot 31 Aug 2022
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      DOI: 10.1016/j.isci.2022.104942

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    sciencedirect.com/science/article/pii/S2589004222012147
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Polycomb-mediated repression of paternal chromosomes maintains haploid dosage in diploid embryos of Marchantia
    1
    1. scibot 27 Aug 2022
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      DOI: 10.7554/eLife.79258

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    ncbi.nlm.nih.gov/pmc/articles/PMC9402228/
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    AR-V7 exhibits non-canonical mechanisms of nuclear import and chromatin engagement in castrate-resistant prostate cancer
    1
    1. scibot 26 Aug 2022
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      DOI: 10.7554/eLife.73396

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    ncbi.nlm.nih.gov/pmc/articles/PMC9398446/
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    RAD51 protects human cells from transcription-replication conflicts
    1
    1. scibot 26 Aug 2022
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      DOI: 10.1016/j.molcel.2022.07.010

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    sciencedirect.com/science/article/pii/S1097276522007067
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    Molecular conflicts disrupting centromere maintenance contribute to Xenopus hybrid inviability
    1
    1. scibot 16 Aug 2022
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      DOI: 10.1016/j.cub.2022.07.037

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    sciencedirect.com/science/article/pii/S0960982222011745
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    Discovery of compounds that reactivate p53 mutants in vitro and in vivo
    1
    1. scibot 12 Aug 2022
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      DOI: 10.1016/j.chembiol.2022.07.003

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    sciencedirect.com/science/article/pii/S2451945622002756
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    mTORC1 is required for epigenetic silencing during β-cell functional maturation
    1
    1. scibot 10 Aug 2022
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      DOI: 10.1016/j.molmet.2022.101559

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    sciencedirect.com/science/article/pii/S2212877822001284
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    Broad-spectrum chemicals block ROS detoxification to prevent plant fungal invasion
    1
    1. scibot 06 Aug 2022
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      DOI: 10.1016/j.cub.2022.07.022

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    sciencedirect.com/science/article/pii/S096098222201123X
  15. Jul 2022
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A non-transcriptional function of Yap regulates the DNA replication program in Xenopus laevis
    1
    1. scibot 31 Jul 2022
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      DOI: 10.7554/eLife.75741

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    ncbi.nlm.nih.gov/pmc/articles/PMC9328763/
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    Acetylation of p62 regulates base excision repair through interaction with APE1
    1
    1. scibot 27 Jul 2022
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      DOI: 10.1016/j.celrep.2022.111116

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    sciencedirect.com/science/article/pii/S2211124722009226
  18. yc.mlpla.mil.cn yc.mlpla.mil.cn
    Temporal resolution of gene derepression and proteome changes upon PROTAC-mediated degradation of BCL11A protein in erythroid cells
    1
    1. scibot 15 Jul 2022
      RRID:AB_302613

      DOI: 10.1016/j.chembiol.2022.06.007

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    yc.mlpla.mil.cn/s/com/sciencedirect/www/G.https/science/article/pii/S2451945622002392
  19. academic.oup.com academic.oup.com
    Induction of senescence upon loss of the Ash2l core subunit of H3K4 methyltransferase complexes
    1
    1. scibot 13 Jul 2022
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      DOI: 10.1093/nar/gkac591

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    academic.oup.com/nar/advance-article/doi/10.1093/nar/gkac591/6640223
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Phase separation of HRLP regulates flowering time in Arabidopsis
    1
    1. scibot 09 Jul 2022
      RRID:AB_302613

      DOI: 10.1126/sciadv.abn5488

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    ncbi.nlm.nih.gov/pmc/articles/PMC9217094/
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    Inhibition of DYRK1A, via histone modification, promotes cardiomyocyte cell cycle activation and cardiac repair after myocardial infarction
    1
    1. scibot 09 Jul 2022
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      DOI: 10.1016/j.ebiom.2022.104139

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    sciencedirect.com/science/article/pii/S2352396422003206
  22. Jun 2022
  23. 52.53.155.43 52.53.155.43
    cd-21-1514-html.html
    3
    1. scibot 30 Jun 2022
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      DOI: 10.1158/2159-8290.CD-21-1514

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    2. scibot 25 Jun 2022
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      DOI: 10.1158/2159-8290.cd-21-1514

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    3. scibot 23 Jun 2022
      RRID:AB_302613

      DOI: 10.1158/2159-8290.cd-21-1514

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    52.53.155.43/30b9574de57b2e4ccfd380c8f4f8e4cb5eb75f43/cd-21-1514-html.html
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    Clioquinol as an inhibitor of JmjC-histone demethylase exhibits common and unique histone methylome and transcriptome between clioquinol and hypoxia
    1
    1. scibot 25 Jun 2022
      RRID:AB_302613

      DOI: 10.1016/j.isci.2022.104517

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    sciencedirect.com/science/article/pii/S258900422200788X
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    Visualization of the dynamic interaction between nucleosomal histone H3K9 tri-methylation and HP1α chromodomain in living cells
    1
    1. scibot 22 Jun 2022
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      DOI: 10.1016/j.chembiol.2022.05.006

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    sciencedirect.com/science/article/pii/S2451945622001982
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    MacroH2As regulate enhancer-promoter contacts affecting enhancer activity and sensitivity to inflammatory cytokines
    1
    1. scibot 22 Jun 2022
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      DOI: 10.1016/j.celrep.2022.110988

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    sciencedirect.com/science/article/pii/S2211124722007744
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    Oncogenic ZMYND11-MBTD1 fusion protein anchors the NuA4/TIP60 histone acetyltransferase complex to the coding region of active genes
    1
    1. scibot 15 Jun 2022
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      DOI: 10.1016/j.celrep.2022.110947

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    sciencedirect.com/science/article/pii/S221112472200729X
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    Analysis of estrogen-regulated enhancer RNAs identifies a functional motif required for enhancer assembly and gene expression
    1
    1. scibot 15 Jun 2022
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      DOI: 10.1016/j.celrep.2022.110944

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    sciencedirect.com/science/article/pii/S2211124722007264
  29. www.sciencedirect.com www.sciencedirect.com
    A rice protein modulates endoplasmic reticulum homeostasis and coordinates with a transcription factor to initiate blast disease resistance
    1
    1. scibot 15 Jun 2022
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      DOI: 10.1016/j.celrep.2022.110941

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    sciencedirect.com/science/article/pii/S2211124722007239
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    A TET1-PSPC1-Neat1 molecular axis modulates PRC2 functions in controlling stem cell bivalency
    1
    1. scibot 09 Jun 2022
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      DOI: 10.1016/j.celrep.2022.110928

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    sciencedirect.com/science/article/pii/S2211124722007100
  31. www.sciencedirect.com www.sciencedirect.com
    Breaking boundaries: Pan BETi disrupt 3D chromatin structure, BD2-selective BETi are strictly epigenetic transcriptional regulators
    1
    1. scibot 08 Jun 2022
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      DOI: 10.1016/j.biopha.2022.113230

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    sciencedirect.com/science/article/pii/S0753332222006199
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    JAZF1-SUZ12 dysregulates PRC2 function and gene expression during cell differentiation
    1
    1. scibot 03 Jun 2022
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      DOI: 10.1016/j.celrep.2022.110889

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    sciencedirect.com/science/article/pii/S2211124722006647
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Oct4 differentially regulates chromatin opening and enhancer transcription in pluripotent stem cells
    1
    1. scibot 01 Jun 2022
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      DOI: 10.7554/eLife.71533

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    ncbi.nlm.nih.gov/pmc/articles/PMC9142147/
  34. May 2022
  35. www.nature.com www.nature.com
    Alcohol induced increases in sperm Histone H3 lysine 4 trimethylation correlate with increased placental CTCF occupancy and altered developmental programming
    1
    1. scibot 26 May 2022
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      DOI: 10.1038/s41598-022-12188-3

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    nature.com/articles/s41598-022-12188-3
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    Xist-mediated silencing requires additive functions of SPEN and Polycomb together with differentiation-dependent recruitment of SmcHD1
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      DOI: 10.1016/j.celrep.2022.110830

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    sciencedirect.com/science/article/pii/S2211124722006015
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    Twist2-driven chromatin remodeling governs the postnatal maturation of dermal fibroblasts
    1
    1. scibot 19 May 2022
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      DOI: 10.1016/j.celrep.2022.110821

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    sciencedirect.com/science/article/pii/S2211124722005927
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    Single-cell analysis of human testis aging and correlation with elevated body mass index
    1
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      DOI: 10.1016/j.devcel.2022.04.004

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    sciencedirect.com/science/article/pii/S1534580722002441
  39. Apr 2022
  40. www.sciencedirect.com www.sciencedirect.com
    H3K4 methylation by SETD1A/BOD1L facilitates RIF1-dependent NHEJ
    1
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      DOI: 10.1016/j.molcel.2022.03.030

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    sciencedirect.com/science/article/pii/S1097276522002684
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    CDYL1-dependent decrease in lysine crotonylation at DNA double-strand break sites functionally uncouples transcriptional silencing and repair
    1
    1. scibot 21 Apr 2022
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      DOI: 10.1016/j.molcel.2022.03.031

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    sciencedirect.com/science/article/pii/S1097276522002696
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    Microtubules promote the non-cell autonomous action of microRNAs by inhibiting their cytoplasmic loading onto ARGONAUTE1 in Arabidopsis
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      DOI: 10.1016/j.devcel.2022.03.015

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    sciencedirect.com/science/article/pii/S153458072200209X
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    Heat-induced SIRT1-mediated H4K16ac deacetylation impairs resection and SMARCAD1 recruitment to double strand breaks
    2
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      DOI: 10.1016/j.isci.2022.104142

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      AB_1791

      DOI: 10.1016/j.isci.2022.104142

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    sciencedirect.com/science/article/pii/S2589004222004126
  44. www.sciencedirect.com www.sciencedirect.com
    CTCF functions as an insulator for somatic genes and a chromatin remodeler for pluripotency genes during reprogramming
    1
    1. scibot 07 Apr 2022
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      DOI: 10.1016/j.celrep.2022.110626

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    sciencedirect.com/science/article/pii/S2211124722003746
  45. aacrjournals.org aacrjournals.org
    PGC1α/β EXPRESSION PREDICTS THERAPEUTIC RESPONSE TO OXIDATIVE PHOSPHORYLATION INHIBITION IN OVARIAN CANCER
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  46. Mar 2022
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The TFIIH complex is required to establish and maintain mitotic chromosome structure
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    Chromatin modifier HUSH co-operates with RNA decay factor NEXT to restrict transposable element expression
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    Histone deacetylation regulates nucleotide excision repair through an interaction with the XPC protein
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    Liquid-to-solid phase transition of oskar ribonucleoprotein granules is essential for their function in Drosophila embryonic development
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    Neddylation is essential for β-catenin degradation in Wnt signaling pathway
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    FBXO47 is essential for preventing the synaptonemal complex from premature disassembly in mouse male meiosis
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  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Distinct and diverse chromatin proteomes of ageing mouse organs reveal protein signatures that correlate with physiological functions
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    A trio of ubiquitin ligases sequentially drives ubiquitylation and autophagic degradation of dysfunctional yeast proteasomes
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    Dynamic control of chromatin-associated m6A methylation regulates nascent RNA synthesis
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    An Inducible CRISPR/Cas9 Screen Identifies DTX2 as a Transcriptional Regulator of Human Telomerase
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    dCas9 fusion to computer-designed PRC2 inhibitor reveals functional TATA box in distal promoter region
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  58. Feb 2022
  59. elifesciences.org elifesciences.org
    Repression of hypoxia-inducible factor-1 contributes to increased mitochondrial reactive oxygen species production in diabetes
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    Ketogenic diet and chemotherapy combine to disrupt pancreatic cancer metabolism and growth
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    E3 ligase RNF167 and deubiquitinase STAMBPL1 modulate mTOR and cancer progression
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  62. Jan 2022
  63. www.cell.com www.cell.com
    Pseudouridine synthases modify human pre-mRNA co-transcriptionally and affect pre-mRNA processing
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    Type I and II PRMTs inversely regulate post-transcriptional intron detention through Sm and CHTOP methylation
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  65. link.springer.com link.springer.com
    Histone acetyltransferase NAA40 modulates acetyl-CoA levels and lipid synthesis
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    Chromatin alterations during the epididymal maturation of mouse sperm refine the paternally inherited epigenome
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  67. Dec 2021
  68. www.sciencedirect.com www.sciencedirect.com
    EMSY inhibits homologous recombination repair and the interferon response, promoting lung cancer immune evasion
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    IFI16 inhibits DNA repair that potentiates type-I interferon-induced antitumor effects in triple negative breast cancer
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    Potent macrocycle inhibitors of the human SAGA deubiquitinating module
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    Evolution of a histone variant involved in compartmental regulation of NAD metabolism
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  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pharmacological targeting of Sam68 functions in colorectal cancer stem cells
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  73. www.cell.com www.cell.com
    MYC assembles and stimulates topoisomerases 1 and 2 in a “topoisome”
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    The protease SPRTN and SUMOylation coordinate DNA-protein crosslink repair to prevent genome instability
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    Methods to separate nuclear soluble fractions reflecting localizations in living cells
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    SUMOylation of linker histone H1 drives chromatin condensation and restriction of embryonic cell fate identity
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    Sumoylation of the human histone H4 tail inhibits p300-mediated transcription by RNA polymerase II in cellular extracts
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    Ago1 controls myogenic differentiation by regulating eRNA-mediated CBP-guided epigenome reprogramming
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  79. Nov 2021
  80. www.cell.com www.cell.com
    MYCN recruits the nuclear exosome complex to RNA polymerase II to prevent transcription-replication conflicts
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    Transcription-wide mapping of dihydrouridine reveals that mRNA dihydrouridylation is required for meiotic chromosome segregation
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    Topoisomerase 1 activity during mitotic transcription favors the transition from mitosis to G1
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    Acetyl-CoA derived from hepatic mitochondrial fatty acid β-oxidation aggravates inflammation by enhancing p65 acetylation
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    DDK/Hsk1 phosphorylates and targets fission yeast histone deacetylase Hst4 for degradation to stabilize stalled DNA replication forks
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    A role for SMARCB1 in synovial sarcomagenesis reveals that SS18-SSX induces canonical BAF destruction
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    Glut1 expression in tumor-associated neutrophils promotes lung cancer growth and resistance to radiotherapy
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    Identification of the sex-determining factor in the liverwort Marchantia polymorpha reveals unique evolution of sex chromosomes in a haploid system
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  88. Oct 2021
  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A complex of BRCA2 and PP2A-B56 is required for DNA repair by homologous recombination
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    The BORDER family of negative transcription elongation factors regulates flowering time in Arabidopsis
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    The Splicing Factor hnRNP M Is a Critical Regulator of Innate Immune Gene Expression in Macrophages
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    Histone Variant and Cell Context Determine H3K27M Reprogramming of the Enhancer Landscape and Oncogenic State
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    Nuclear PGK1 Alleviates ADP-Dependent Inhibition of CDC7 to Promote DNA Replication
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    ATRX In-Frame Fusion Neuroblastoma Is Sensitive to EZH2 Inhibition via Modulation of Neuronal Gene Signatures
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    Widespread Accumulation of Ribosome-Associated Isolated 3′ UTRs in Neuronal Cell Populations of the Aging Brain
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    The Nuclear Matrix Protein SAFB Cooperates with Major Satellite RNAs to Stabilize Heterochromatin Architecture Partially through Phase Separation
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    VAL genes regulate vegetative phase change via miR156-dependent and independent mechanisms
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    The Polycomb group protein MEDEA controls cell proliferation and embryonic patterning in Arabidopsis
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    The nuclear kinesin KIF18B promotes 53BP1-mediated DNA double-strand break repair
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    BAP1 enhances Polycomb repression by counteracting widespread H2AK119ub1 deposition and chromatin condensation
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  178. www.sciencedirect.com www.sciencedirect.com
    Nascent RNA antagonizes the interaction of a set of regulatory proteins with chromatin
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  179. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A TORC1-histone axis regulates chromatin organisation and non-canonical induction of autophagy to ameliorate ageing
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      DOI: 10.7554/eLife.62233

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  180. link.springer.com link.springer.com
    Programmed suppression of oxidative phosphorylation and mitochondrial function by gestational alcohol exposure correlate with widespread increases in H3K9me2 that do not suppress transcription
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      DOI: 10.1186/s13072-021-00403-w

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    Correct dosage of X chromosome transcription is controlled by a nuclear pore component
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      DOI: 10.1016/j.celrep.2021.109236

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    XRCC1 prevents toxic PARP1 trapping during DNA base excision repair
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    Cystatin B-deficiency triggers ectopic histone H3 tail cleavage during neurogenesis
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  184. bmcbiol.biomedcentral.com bmcbiol.biomedcentral.com
    Boundaries potentiate polycomb response element-mediated silencing
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      DOI: 10.1186/s12915-021-01047-8

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    Uncovering the RNA-binding protein landscape in the pluripotency network of human embryonic stem cells
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      DOI: 10.1016/j.celrep.2021.109198

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    Choline kinase alpha 2 acts as a protein kinase to promote lipolysis of lipid droplets
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  187. May 2021
  188. www.nature.com www.nature.com
    Guiding functions of the C-terminal domain of topoisomerase IIα advance mitotic chromosome assembly
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      DOI: 10.1038/s41467-021-23205-w

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  189. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Suppression of β-catenin signaling in colon carcinoma cells by a bacterial protein
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      rabbit polyclonal anti-histone H3

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    Human telomerase is directly regulated by non-telomeric TRF2-G-quadruplex interaction
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    CloneSeq: A highly sensitive analysis platform for the characterization of 3D-cultured single-cell-derived clones
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    The PP2A-Integrator-CDK9 axis fine-tunes transcription and can be targeted therapeutically in cancer
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    DHODH inhibition modulates glucose metabolism and circulating GDF15, and improves metabolic balance
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    Missense mutations in small muscle protein X-linked ( SMPX ) cause distal myopathy with protein inclusions
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      DOI: 10.1007/s00401-021-02319-x

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    Methylation of histone H3 at lysine 37 by Set1 and Set2 prevents spurious DNA replication
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  196. journals.physiology.org journals.physiology.org
    Inhibition of miR-155 potentially protects Lipopolysaccharide-induced acute lung injury through the IRF2BP2-NFAT1 pathway
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      DOI: 10.1152/ajpcell.00116.2020

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    Spermiogenic histone transitions and chromatin decondensation in Decapoda
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      DOI: 10.1016/j.theriogenology.2020.07.003

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    Pathogenic LMNA variants disrupt cardiac lamina-chromatin interactions and de-repress alternative fate genes
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      DOI: 10.1016/j.stem.2020.12.016

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    Histone crotonylation promotes mesoendodermal commitment of human embryonic stem cells
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    Histone Acetyltransferase MOF Blocks Acquisition of Quiescence in Ground-State ESCs through Activating Fatty Acid Oxidation
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    Ubiquitin Phosphorylation at Thr12 Modulates the DNA Damage Response
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    PCAF-Mediated Histone Acetylation Promotes Replication Fork Degradation by MRE11 and EXO1 in BRCA-Deficient Cells
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      DOI: 10.1016/j.molcel.2020.08.018

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    HLTF Promotes Fork Reversal, Limiting Replication Stress Resistance and Preventing Multiple Mechanisms of Unrestrained DNA Synthesis
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    Genome-wide Screens Identify Lineage- and Tumor-Specific Genes Modulating MHC-I- and MHC-II-Restricted Immunosurveillance of Human Lymphomas
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      DOI: 10.1016/j.immuni.2020.11.002

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    A Hyper-IgM Syndrome Mutation in Activation-Induced Cytidine Deaminase Disrupts G-Quadruplex Binding and Genome-wide Chromatin Localization
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    A Prion-like Domain in Transcription Factor EBF1 Promotes Phase Separation and Enables B Cell Programming of Progenitor Chromatin
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    Homology-directed repair protects the replicating genome from metabolic assaults
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      DOI: 10.1002/1878-0261.12953

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    Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains
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    H3K27ac bookmarking promotes rapid post-mitotic activation of the pluripotent stem cell program without impacting 3D chromatin reorganization
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  211. Apr 2021
  212. www.sciencedirect.com www.sciencedirect.com
    STAG2 mutations alter CTCF-anchored loop extrusion, reduce cis-regulatory interactions and EWSR1-FLI1 activity in Ewing sarcoma
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