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Dec 2020
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Spatial Multiplexing of Fluorescent Reporters for Imaging Signaling Network Dynamics

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  DOI: 10.1016/j.cell.2020.10.035
  
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sciencedirect.com/science/article/pii/S0092867420313994
Nov 2020
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A Ca2+-Dependent Switch Activates Axonal Casein Kinase 2α Translation and Drives G3BP1 Granule Disassembly for Axon Regeneration

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1. scibot 19 Nov 2020
  
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  DOI: 10.1016/j.cub.2020.09.043
  
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cell.com/current-biology/abstract/S0960-9822(20)31413-5
Oct 2020
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Functional Diversification of SRSF Protein Kinase to Control Ubiquitin-Dependent Neurodevelopmental Signaling

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  DOI: 10.1016/j.devcel.2020.09.025
  
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sciencedirect.com/science/article/pii/S1534580720307577
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Olfactory Stimulation Regulates the Birth of Neurons That Express Specific Odorant Receptors

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  DOI: 10.1016/j.celrep.2020.108210
  
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sciencedirect.com/science/article/pii/S2211124720311992
Sep 2020
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MYC Controls the Epstein-Barr Virus Lytic Switch

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sciencedirect.com/science/article/pii/S1097276520301933
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The orphan receptor GPR88 blunts the signaling of opioid receptors and multiple striatal GPCRs

1
1. scibot 25 Sep 2020
  
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  DOI: 10.7554/eLife.50519
  
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elifesciences.org/articles/50519
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ZCWPW1 is recruited to recombination hotspots by PRDM9 and is essential for meiotic double strand break repair

1
1. scibot 23 Sep 2020
  
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  DOI: 10.7554/eLife.53392
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7494361/
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p53 Integrates Temporal WDR5 Inputs during Neuroectoderm and Mesoderm Differentiation of Mouse Embryonic Stem Cells

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1. scibot 23 Sep 2020
  
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sciencedirect.com/science/article/pii/S2211124719316961
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Elongation inhibitors do not prevent the release of puromycylated nascent polypeptide chains from ribosomes

1
1. scibot 23 Sep 2020
  
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  DOI: 10.7554/eLife.60048
  
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elifesciences.org/articles/60048
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The Protein Translocation Defect of MCT8L291R Is Rescued by Sodium Phenylbutyrate

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  DOI: 10.1159/000507439
  
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karger.com/Article/FullText/507439
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Promiscuous Binding of Microprotein Mozart1 to γ-Tubulin Complex Mediates Specific Subcellular Targeting to Control Microtubule Array Formation

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1. scibot 17 Sep 2020
  
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sciencedirect.com/science/article/pii/S2211124720308172
currentprotocols.onlinelibrary.wiley.com currentprotocols.onlinelibrary.wiley.com

Translatome Analyses Using Conditional Ribosomal Tagging in GABAergic Interneurons and Other Sparse Cell Types

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1. scibot 17 Sep 2020
  
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  DOI: 10.1002/cpns.93
  
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currentprotocols.onlinelibrary.wiley.com/doi/10.1002/cpns.93
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The GATA Transcription Factor Gaf1 Represses tRNAs, Inhibits Growth, and Extends Chronological Lifespan Downstream of Fission Yeast TORC1

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1. scibot 17 Sep 2020
  
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sciencedirect.com/science/article/pii/S2211124720302266
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Endothelial heterogeneity across distinct vascular beds during homeostasis and inflammation

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1. scibot 17 Sep 2020
  
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  DOI: 10.7554/eLife.51413
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7002042/
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KRAB-zinc finger protein gene expansion in response to active retrotransposons in the murine lineage

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1. scibot 15 Sep 2020
  
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  DOI: 10.7554/eLife.56337
  
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elifesciences.org/articles/56337
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Localized Inhibition of Protein Phosphatase 1 by NUAK1 Promotes Spliceosome Activity and Reveals a MYC-Sensitive Feedback Control of Transcription

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1. scibot 14 Sep 2020
  
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  DOI: 10.1016/j.molcel.2020.01.008
  
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sciencedirect.com/science/article/pii/S1097276520300083
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MEIOSIN Directs the Switch from Mitosis to Meiosis in Mammalian Germ Cells

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1. scibot 13 Sep 2020
  
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  DOI: 10.1016/j.devcel.2020.01.010
  
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sciencedirect.com/science/article/pii/S1534580720300113
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Acetylation Stabilizes Phosphoglycerate Dehydrogenase by Disrupting the Interaction of E3 Ligase RNF5 to Promote Breast Tumorigenesis

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1. scibot 12 Sep 2020
  
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  DOI: 10.1016/j.celrep.2020.108021
  
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sciencedirect.com/science/article/pii/S2211124720310068
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G3BP1 Is a Tunable Switch that Triggers Phase Separation to Assemble Stress Granules

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1. scibot 10 Sep 2020
  
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  DOI: 10.1016/j.cell.2020.03.046
  
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sciencedirect.com/science/article/pii/S0092867420303391
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PRL3-DDX21 Transcriptional Control of Endolysosomal Genes Restricts Melanocyte Stem Cell Differentiation

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  DOI: 10.1016/j.devcel.2020.06.013
  
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sciencedirect.com/science/article/pii/S1534580720304639
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Activity-Dependent Netrin-1 Secretion Drives Synaptic Insertion of GluA1-Containing AMPA Receptors in the Hippocampus

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  DOI: 10.1016/j.celrep.2018.09.028
  
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cell.com/cell-reports/fulltext/S2211-1247(18)31458-X
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Histones, DNA, and Citrullination Promote Neutrophil Extracellular Trap Inflammation by Regulating the Localization and Activation of TLR4

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1. scibot 04 Sep 2020
  
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sciencedirect.com/science/article/pii/S2211124720305519
Jan 2020
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SAMHD1 Modulates Early Steps during Human Cytomegalovirus Infection by Limiting NF-κB Activation

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  DOI: 10.1016/j.celrep.2019.06.027
  
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sciencedirect.com/science/article/pii/S2211124719307934
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Structural Basis of an Asymmetric Condensin ATPase Cycle

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  DOI: 10.1016/j.molcel.2019.03.037
  
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sciencedirect.com/science/article/pii/S1097276519302667
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A Non-canonical Role of YAP/TEAD Is Required for Activation of Estrogen-Regulated Enhancers in Breast Cancer

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sciencedirect.com/science/article/pii/S1097276519304435
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Degradation of Polycomb Repressive Complex 2 with an EED-Targeted Bivalent Chemical Degrader

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  DOI: 10.1016/j.chembiol.2019.11.006
  
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sciencedirect.com/science/article/pii/S2451945619303642
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TRIM32/USP11 Balances ARID1A Stability and the Oncogenic/Tumor-Suppressive Status of Squamous Cell Carcinoma

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  DOI: 10.1016/j.celrep.2019.12.017
  
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sciencedirect.com/science/article/pii/S2211124719316675
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SETDB1-Mediated Cell Fate Transition between 2C-Like and Pluripotent States

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  DOI: 10.1016/j.celrep.2019.12.010
  
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sciencedirect.com/science/article/pii/S2211124719316493
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Stem cell-derived cranial and spinal motor neurons reveal proteostatic differences between ALS resistant and sensitive motor neurons

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  DOI: 10.7554/eLife.44423
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6594754/
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Nuclear AGO1 Regulates Gene Expression by Affecting Chromatin Architecture in Human Cells

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  DOI: 10.1016/j.cels.2019.09.005
  
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sciencedirect.com/science/article/pii/S2405471219303138
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Reconstituting Drosophila Centromere Identity in Human Cells

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  DOI: 10.1016/j.celrep.2019.08.067
  
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sciencedirect.com/science/article/pii/S2211124719311222
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Junctophilin Proteins Tether a Cav1-RyR2-KCa3.1 Tripartite Complex to Regulate Neuronal Excitability

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  DOI: 10.1016/j.celrep.2019.07.075
  
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sciencedirect.com/science/article/pii/S2211124719309799
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Mitochondrially-targeted APOBEC1 is a potent mtDNA mutator affecting mitochondrial function and organismal fitness in Drosophila

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  DOI: 10.1038/s41467-019-10857-y
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6650417/
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Transcriptional profiling aligned with in situ expression image analysis reveals mosaically‐expressed molecular markers for GABA neuron sub‐groups in the ventral tegmental area

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  DOI: 10.1111/ejn.14534
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6972656/
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Distinct Classes of Chromatin Loops Revealed by Deletion of an RNA-Binding Region in CTCF

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Synaptic Kalirin-7 and Trio Interactomes Reveal a GEF Protein-Dependent Neuroligin-1 Mechanism of Action

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FMRP has a cell-type-specific role in CA1 pyramidal neurons to regulate autism-related transcripts and circadian memory

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RAG-Mediated DNA Breaks Attenuate PU.1 Activity in Early B Cells through Activation of a SPIC-BCLAF1 Complex

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Comprehensive Genetic Characterization of Mitochondrial Ca2+ Uniporter Components Reveals Their Different Physiological Requirements In Vivo

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Intrinsic Structural Features of the Human IRE1α Transmembrane Domain Sense Membrane Lipid Saturation

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RRM Transcription Factors Interact with NLRs and Regulate Broad-Spectrum Blast Resistance in Rice

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Nucleoporin Seh1 Interacts with Olig2/Brd7 to Promote Oligodendrocyte Differentiation and Myelination

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Modeling the Biochemical Phenotype of MCT8 Mutations In Vitro: Resolving a Troubling Inconsistency

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Identification of a Single Pair of Interneurons for Bitter Taste Processing in the Drosophila Brain

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Phosphorylation of Histone H4T80 Triggers DNA Damage Checkpoint Recovery

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A Single-Dose Live-Attenuated Zika Virus Vaccine with Controlled Infection Rounds that Protects against Vertical Transmission

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HOXA9 Reprograms the Enhancer Landscape to Promote Leukemogenesis

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ZFX Mediates Non-canonical Oncogenic Functions of the Androgen Receptor Splice Variant 7 in Castrate-Resistant Prostate Cancer

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MEF2B Instructs Germinal Center Development and Acts as an Oncogene in B Cell Lymphomagenesis

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Repression of Somatic Genes by Selective Recruitment of HDAC3 by BLIMP1 Is Essential for Mouse Primordial Germ Cell Fate Determination

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SIRT1 Activation Disrupts Maintenance of Myelodysplastic Syndrome Stem and Progenitor Cells by Restoring TET2 Function

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Combinatorial CRISPR/Cas9 Approach to Elucidate a Far-Upstream Enhancer Complex for Tissue-Specific Sox9 Expression

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Dismissal of RNA Polymerase II Underlies a Large Ligand-Induced Enhancer Decommissioning Program

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GRHL2-Dependent Enhancer Switching Maintains a Pluripotent Stem Cell Transcriptional Subnetwork after Exit from Naive Pluripotency

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TALE factors use two distinct functional modes to control an essential zebrafish gene expression program

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Capturing the Onset of PRC2-Mediated Repressive Domain Formation

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Allele-Specific Chromatin Recruitment and Therapeutic Vulnerabilities of ESR1 Activating Mutations

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A C9orf72 ALS/FTD Ortholog Acts in Endolysosomal Degradation and Lysosomal Homeostasis

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The SS18-SSX Oncoprotein Hijacks KDM2B-PRC1.1 to Drive Synovial Sarcoma

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Germline Genetic IKZF1 Variation and Predisposition to Childhood Acute Lymphoblastic Leukemia

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Structural Basis for Regulated Proteolysis by the α-Secretase ADAM10

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CBP Regulates Recruitment and Release of Promoter-Proximal RNA Polymerase II

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Fission Yeast CSL Transcription Factors: Mapping Their Target Genes and Biological Roles

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journals.plos.org/plosone/article
academic.oup.com academic.oup.com

Tac1 Signaling Is Required for Sexual Maturation and Responsiveness of GnRH Neurons to Kisspeptin in the Male Mouse

1
1. scibot 08 Nov 2017
  
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  AB_307019
  
  Curator: @chewbeccax
  
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academic.oup.com/endo/article/158/7/2319/3746606/Tac1-Signaling-Is-Required-for-Sexual-Maturation
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Wnt-Dependent Inactivation of the Groucho/TLE Co-repressor by the HECT E3 Ubiquitin Ligase Hyd/UBR5

1
1. scibot 08 Nov 2017
  
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  AB_307019
  
  Curator: @chewbeccax
  
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sciencedirect.com/science/article/pii/S1097276517304367
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The murine catecholamine methyltransferase mTOMT is essential for mechanotransduction by cochlear hair cells

1
1. scibot 08 Nov 2017
  
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  AB_307019
  
  Curator: @chewbeccax
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5462538/
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Heterogeneous Ribosomes Preferentially Translate Distinct Subpools of mRNAs Genome-wide

1
1. scibot 08 Nov 2017
  
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  AB_307019
  
  Curator: @chewbeccax
  
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sciencedirect.com/science/article/pii/S1097276517303611
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Representations of Novelty and Familiarity in a Mushroom Body Compartment

1
1. scibot 08 Nov 2017
  
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  AB_307019
  
  Curator: @Zeljana_Babic
  
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sciencedirect.com/science/article/pii/S0092867417304798
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Multi-site Neurogenin3 Phosphorylation Controls Pancreatic Endocrine Differentiation

1
1. scibot 08 Nov 2017
  
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  AB_307019
  
  Curator: @kaitlinsung
  
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sciencedirect.com/science/article/pii/S1534580717302976
elifesciences.org elifesciences.org

DNA-mediated association of two histone-bound complexes of yeast Chromatin Assembly Factor-1 (CAF-1) drives tetrasome assembly in the wake of DNA replication

1
1. scibot 08 Nov 2017
  
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  AB_307019
  
  Curator: @Zeljana_Babic
  
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elifesciences.org/articles/22799
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Myrf ER-Bound Transcription Factors Drive C. elegans Synaptic Plasticity via Cleavage-Dependent Nuclear Translocation

1
1. scibot 08 Nov 2017
  
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  AB_307019
  
  Curator: @gabimpine
  
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sciencedirect.com/science/article/pii/S1534580717302083
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Gene Resistance to Transcriptional Reprogramming following Nuclear Transfer Is Directly Mediated by Multiple Chromatin-Repressive Pathways

1
1. scibot 08 Nov 2017
  
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  AB_307019
  
  Curator: @Zeljana_Babic
  
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sciencedirect.com/science/article/pii/S1097276517300564
elifesciences.org elifesciences.org

Multiplex image-based autophagy RNAi screening identifies SMCR8 as ULK1 kinase activity and gene expression regulator

1
1. scibot 08 Nov 2017
  
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  AB_307019
  
  Curator: @kaitlinsung
  
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elifesciences.org/articles/23063
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PHB Associates with the HIRA Complex to Control an Epigenetic-Metabolic Circuit in Human ESCs

1
1. scibot 08 Nov 2017
  
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  AB_307019
  
  Curator: @gabimpine
  
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sciencedirect.com/science/article/pii/S1934590916303988
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Diversity and wiring variability of visual local neurons in the Drosophila medulla M6 stratum

1
1. scibot 08 Nov 2017
  
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  AB_307019
  
  Curator: @gabimpine
  
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ncbi.nlm.nih.gov/pmc/articles/PMC4265792/