627 Matching Annotations
  1. May 2023
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    Impacts of High Fructose Diet and Chronic Exercise on Nitric Oxide Synthase and Oxidative Stress in Rat Kidney
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    mdpi.com/2072-6643/15/10/2322
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    AKT activation because of PTEN loss upregulates xCT via GSK3β/NRF2, leading to inhibition of ferroptosis in PTEN-mutant tumor cells
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    sciencedirect.com/science/article/pii/S2211124723005478
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    PAC1 deficiency protects obese male mice from immobilization-induced muscle atrophy by suppressing FoxO-atrogene axis
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    52.53.155.43/bdf89ee8b17f684d89776b136763c0415969fc5a/RRID9-html.html
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PICK1-Deficient Mice Maintain Their Glucose Tolerance During Diet-Induced Obesity
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    ncbi.nlm.nih.gov/pmc/articles/PMC10185814/
  6. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Dihydroartemisinin inhibited stem cell-like properties and enhanced oxaliplatin sensitivity of colorectal cancer via AKT/mTOR signaling
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    onlinelibrary.wiley.com/doi/10.1002/ddr.22067
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    Inhibition of BRAF and ERK1/2 has synergistic effects on thyroid cancer growth in vitro and in vivo
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    onlinelibrary.wiley.com/doi/full/10.1002/mc.23284
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    Co-modulation of TNFR1 and TNFR2 in an animal model of multiple sclerosis
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    link.springer.com/article/10.1186/s12974-023-02784-z
  9. Apr 2023
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    PSGL-1 attenuates early TCR signaling to suppress CD8+ T cell progenitor differentiation and elicit terminal CD8+ T cell exhaustion
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    sciencedirect.com/science/article/pii/S2211124723004473
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    Piezo1 induces endothelial responses to shear stress via soluble adenylyl Cyclase-IP3R2 circuit
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    sciencedirect.com/science/article/pii/S2589004223007381
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    Mitochondrial cannabinoid receptors gate corticosterone impact on novel object recognition
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    sciencedirect.com/science/article/pii/S0896627323002635
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    Live-cell imaging identifies cAMP microdomains regulating β-adrenoceptor-subtype-specific lipolytic responses in human white adipocytes
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    sciencedirect.com/science/article/pii/S2211124723004448
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    Fructose-1,6-bisphosphatase is a nonenzymatic safety valve that curtails AKT activation to prevent insulin hyperresponsiveness
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    sciencedirect.com/science/article/pii/S1550413123001262
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    RhoB promotes Salmonella survival by regulating autophagy
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    biorxiv.org/content/10.1101/2023.04.05.535690v1
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    Single targeting of MET in EGFR-mutated and MET-amplified non-small cell lung cancer
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    nature.com/articles/s41416-023-02264-4
  17. link.springer.com link.springer.com
    Statins enhances antitumor effect of oxaliplatin in KRAS-mutated colorectal cancer cells and inhibits oxaliplatin-induced neuropathy
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    link.springer.com/article/10.1186/s12935-023-02884-z
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    AKT activity orchestrates marginal zone B cell development in mice and humans
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    sciencedirect.com/science/article/pii/S2211124723003893
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    A human skeletal muscle stem/myotube model reveals multiple signaling targets of cancer secretome in skeletal muscle
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    sciencedirect.com/science/article/pii/S2589004223006181
  20. iubmb.onlinelibrary.wiley.com iubmb.onlinelibrary.wiley.com
    Rapamycin treatment unmasks a sex-specific pattern of scar expansion of the infarcted rat heart: The relationship between mTOR and KATP channel
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    iubmb.onlinelibrary.wiley.com/doi/10.1002/iub.2722
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    PYHIN protein IFI207 regulates cytokine transcription and IRF7 and contributes to the establishment of K. pneumoniae infection
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    sciencedirect.com/science/article/pii/S2211124723003522
  22. Mar 2023
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    Arginine shortage induces replication stress and confers genotoxic resistance by inhibiting histone H4 translation and promoting PCNA ubiquitination
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    sciencedirect.com/science/article/pii/S2211124723003078
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Combining MEK and SRC inhibitors for treatment of colorectal cancer demonstrate increased efficacy in vitro but not in vivo
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    ncbi.nlm.nih.gov/pmc/articles/PMC10035898/
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Exercise-acclimated microbiota improves skeletal muscle metabolism via circulating bile acid deconjugation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10005909/
  26. Feb 2023
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NRF3 activates mTORC1 arginine-dependently for cancer cell viability
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    ncbi.nlm.nih.gov/pmc/articles/PMC9932127/
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IGF-binding proteins secreted by cancer-associated fibroblasts induce context-dependent drug sensitization of lung cancer cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC9528501/
  29. www.sciencedirect.com www.sciencedirect.com
    CD70 is a therapeutic target upregulated in EMT-associated EGFR tyrosine kinase inhibitor resistance
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    sciencedirect.com/science/article/pii/S1535610823000077
  30. www.sciencedirect.com www.sciencedirect.com
    Chronic cortisol elevation restricts glucose uptake but not insulin responsiveness in zebrafish skeletal muscle
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    sciencedirect.com/science/article/pii/S0016648023000369
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Goji berry (Lycium barbarum) inhibits the proliferation, adhesion, and migration of oral cancer cells by inhibiting the ERK, AKT, and CyclinD cell signaling pathways: an in-vitro study
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    ncbi.nlm.nih.gov/pmc/articles/PMC9887205/
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Distinct but interchangeable subpopulations of colorectal cancer cells with different growth fates and drug sensitivity
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    ncbi.nlm.nih.gov/pmc/articles/PMC9883198/
  33. Jan 2023
  34. www.sciencedirect.com www.sciencedirect.com
    Prolonged hypernutrition impairs TREM2-dependent efferocytosis to license chronic liver inflammation and NASH development
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    sciencedirect.com/science/article/pii/S1074761322006033
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Argon preconditioning protects neuronal cells with a Toll-like receptor-mediated effect
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    ncbi.nlm.nih.gov/pmc/articles/PMC9838174/
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    Glutamine and leucine administration attenuates muscle atrophy in sepsis
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    sciencedirect.com/science/article/pii/S002432052201027X
  37. www.sciencedirect.com www.sciencedirect.com
    SLC7A14 imports GABA to lysosomes and impairs hepatic insulin sensitivity via inhibiting mTORC2
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    sciencedirect.com/science/article/pii/S2211124722018885
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The TAZ-CAMTA1 Fusion Protein Promotes Tumorigenesis via Connective Tissue Growth Factor and Ras–MAPK Signaling in Epithelioid Hemangioendothelioma
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    ncbi.nlm.nih.gov/pmc/articles/PMC9306355/
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of Immunogenic MHC Class II Human HER3 Peptides that Mediate Anti-HER3 CD4+ Th1 Responses and Potential Use as a Cancer Vaccine
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    ncbi.nlm.nih.gov/pmc/articles/PMC9414303/
  40. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Restricted physical activity after volumetric muscle loss alters whole-body and local muscle metabolism
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    physoc.onlinelibrary.wiley.com/doi/10.1113/JP283959
  41. Dec 2022
  42. www.mdpi.com www.mdpi.com
    Dysregulation of ErbB4 Signaling Pathway in the Dorsal Hippocampus after Neonatal Hypoxia-Ischemia and Late Deficits in PV+ Interneurons, Synaptic Plasticity and Working Memory
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    mdpi.com/1422-0067/24/1/508
  43. academic.oup.com academic.oup.com
    Membrane Estrogen Receptor Beta is Sufficient to Mitigate Cardiac Cell Pathology
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    academic.oup.com/endo/article/164/2/bqac200/6867852
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    AKTIP loss is enriched in ERα-positive breast cancer for tumorigenesis and confers endocrine resistance
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    sciencedirect.com/science/article/pii/S2211124722017132
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    The hepatic integrated stress response suppresses the somatotroph axis to control liver damage in nonalcoholic fatty liver disease
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    sciencedirect.com/science/article/pii/S2211124722016916
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    Crosstalk between pro-survival sphingolipid metabolism and complement signaling induces inflammasome-mediated tumor metastasis
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    sciencedirect.com/science/article/pii/S2211124722016205
  47. Nov 2022
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Downregulation of protein kinase C gamma reduces epithelial property and enhances malignant phenotypes in colorectal cancer cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC9672935/
  49. www.sciencedirect.com www.sciencedirect.com
    Neuronal-epithelial cross-talk drives acinar specification via NRG1-ERBB3-mTORC2 signaling
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    sciencedirect.com/science/article/pii/S1534580722007638
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    Grabody B, an IGF1 receptor-based shuttle, mediates efficient delivery of biologics across the blood-brain barrier
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    sciencedirect.com/science/article/pii/S2667237522002351
  51. academic.oup.com academic.oup.com
    CRABP2 is associated with thyroid cancer recurrence and promotes invasion via the integrin/FAK/AKT pathway
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    academic.oup.com/endo/article-abstract/163/12/bqac171/6761323
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    Ketone Body Infusion abrogates Growth Hormone Induced Lipolysis and Insulin Resistance
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    academic.oup.com/jcem/advance-article/doi/10.1210/clinem/dgac595/6761325
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    STAT3 is activated by CTGF-mediated tumor-stroma cross talk to promote HCC progression.
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    sciencedirect.com/science/article/pii/S2352345X22001989
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    RSPO2 promotes progression of ovarian cancer through dual receptor-mediated FAK/Src signaling activation
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    sciencedirect.com/science/article/pii/S2589004222014560
  55. www.nature.com www.nature.com
    DHODH inhibition impedes glioma stem cell proliferation, induces DNA damage, and prolongs survival in orthotopic glioblastoma xenografts
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    nature.com/articles/s41388-022-02517-1
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    Disruption of mTORC1 rescues neuronal overgrowth and synapse function dysregulated by Pten loss
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    sciencedirect.com/science/article/pii/S2211124722014358
  57. Oct 2022
  58. academic.oup.com academic.oup.com
    The mineralocorticoid receptor functions as a key glucose regulator in the skeletal muscle of zebrafish
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    academic.oup.com/endo/article/163/11/bqac149/6679268
  59. academic.oup.com academic.oup.com
    Mineralocorticoid receptors mediates diet - induced lipid infiltration of skeletal muscle and insulin resistance
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    academic.oup.com/endo/article/163/11/bqac145/6678806
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    E2F1 transcription factor mediates a link between fat and islets to promote β cell proliferation in response to acute insulin resistance
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    sciencedirect.com/science/article/pii/S2211124722012773
  61. journals.lww.com journals.lww.com
    Poly-L-ornithine blocks the inhibitory effects of... : Neural Regeneration Research
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  62. Sep 2022
  63. www.sciencedirect.com www.sciencedirect.com
    Targeting of c-MET and AXL by cabozantinib is a potential therapeutic strategy for patients with head and neck cell carcinoma
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    sciencedirect.com/science/article/pii/S2666379122001914
  64. www.mdpi.com www.mdpi.com
    Stimulation of Akt Phosphorylation and Glucose Transport by Metalloporphyrins with Peroxynitrite Decomposition Catalytic Activity
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    mdpi.com/2073-4344/12/8/849
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    BET inhibition induces vulnerability to MCL1 targeting through upregulation of fatty acid synthesis pathway in breast cancer
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    sciencedirect.com/science/article/pii/S2211124722011287
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    Integrated multi-omics analysis of adverse cardiac remodeling and metabolic inflexibility upon ErbB2 and ERRα deficiency
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    nature.com/articles/s42003-022-03942-4
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sheep recombinant IGF-1 promotes organ-specific growth in fetal sheep
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    ncbi.nlm.nih.gov/pmc/articles/PMC9452821/
  68. Aug 2022
  69. www.sciencedirect.com www.sciencedirect.com
    Hyperactivation of mTOR and AKT in a cardiac hypertrophy animal model of Friedreich ataxia
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    sciencedirect.com/science/article/pii/S2405844022016590
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Optimized human intestinal organoid model reveals interleukin-22-dependency of paneth cell formation
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    ncbi.nlm.nih.gov/pmc/articles/PMC9438971/
  71. www.science.org www.science.org
    Functional and biological heterogeneity of KRASQ61 mutations
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    science.org/doi/10.1126/scisignal.abn2694
  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Glutamine metabolism modulates chondrocyte inflammatory response
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    ncbi.nlm.nih.gov/pmc/articles/PMC9371604/
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    The mitochondrial calcium uniporter engages UCP1 to form a thermoporter that promotes thermogenesis
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    sciencedirect.com/science/article/pii/S1550413122003102
  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeted BACE-1 inhibition in microglia enhances amyloid clearance and improved cognitive performance
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    ncbi.nlm.nih.gov/pmc/articles/PMC9299535/
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    Phosphoproteomics of primary AML patient samples reveals rationale for AKT combination therapy and p53 context to overcome selinexor resistance
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    sciencedirect.com/science/article/pii/S2211124722009901
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    Aberrant iron distribution via hepatocyte-stellate cell axis drives liver lipogenesis and fibrosis
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    sciencedirect.com/science/article/pii/S1550413122003059
  77. Jul 2022
  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neuregulin-1 signaling regulates cytokines and chemokines expression and secretion in granulosa cell
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    ncbi.nlm.nih.gov/pmc/articles/PMC9316729/
  79. www.sciencedirect.com www.sciencedirect.com
    Slc12a8 in the lateral hypothalamus maintains energy metabolism and skeletal muscle functions during aging
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    sciencedirect.com/science/article/pii/S2211124722009378
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    A RET::GRB2 fusion in pheochromocytoma defies the classic paradigm of RET oncogenic fusions
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    sciencedirect.com/science/article/pii/S2666379122002221
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BACE-1 inhibition facilitates the transition from homeostatic microglia to DAM-1
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    ncbi.nlm.nih.gov/pmc/articles/PMC9205595/
  82. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neoadjuvant chemotherapy induces genomic and transcriptomic changes in ovarian cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC8936832/
  83. Jun 2022
  84. 52.53.155.43 52.53.155.43
    ajpendo.00293.2021-html.html
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  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Differential effects of excess high-fructose corn syrup on the DNA methylation of hippocampal neurotrophic factor in childhood and adolescence
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    ncbi.nlm.nih.gov/pmc/articles/PMC9205497/
  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Intermittent Theta Burst Stimulation Ameliorates Cognitive Deficit and Attenuates Neuroinflammation via PI3K/Akt/mTOR Signaling Pathway in Alzheimer’s-Like Disease Model
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    ncbi.nlm.nih.gov/pmc/articles/PMC9152158/
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    MiR-690 treatment causes decreased fibrosis and steatosis and restores specific Kupffer cell functions in NASH
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    sciencedirect.com/science/article/pii/S1550413122001905
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    MASTL is enriched in cancerous and pluripotent stem cells and influences OCT1/OCT4 levels
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    sciencedirect.com/science/article/pii/S2589004222007301
  89. aacrjournals.org aacrjournals.org
    Liver Endothelium Promotes HER3-mediated Cell Survival in Colorectal Cancer with Wild-type and Mutant KRAS
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    aacrjournals.org/mcr/article/20/6/996/699064/Liver-Endothelium-Promotes-HER3-Mediated-Cell
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    The focal adhesion protein β-parvin controls cardiomyocyte shape and sarcomere assembly in response to mechanical load
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    sciencedirect.com/science/article/pii/S0960982222008508
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    Active APPL1 sequestration by Plasmodium favors liver-stage development
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  92. academic.oup.com academic.oup.com
    Influence of maternal exercise on glucose and lipid metabolism in offspring stem cells: ENHANCED by Mom
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    academic.oup.com/jcem/advance-article/doi/10.1210/clinem/dgac270/6577152
  93. Apr 2022
  94. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15849
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    Tissue remodeling by an opportunistic pathogen triggers allergic inflammation
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    sciencedirect.com/science/article/pii/S1074761322001728
  96. www.sciencedirect.com www.sciencedirect.com
    Cerebroprotein hydrolysate injection is involved in promoting long-term angiogenesis, vessel diameter and density after cerebral ischemia in mice
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    sciencedirect.com/science/article/pii/S0024320522002685
  97. www.sciencedirect.com www.sciencedirect.com
    Betacellulin promotes tumor development and EGFR mutant lung cancer growth by stimulating the EGFR pathway and suppressing apoptosis
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    sciencedirect.com/science/article/pii/S2589004222004813
  98. link.springer.com link.springer.com
    Energetic metabolic reprogramming in Jurkat DFF40-deficient cancer cells
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    link.springer.com/article/10.1007/s11010-022-04433-0
  99. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lack of Tgfbr1 and Acvr1b synergistically stimulates myofibre hypertrophy and accelerates muscle regeneration
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