558 Matching Annotations
  1. Jul 2022
  2. www.sciencedirect.com www.sciencedirect.com
    A RET::GRB2 fusion in pheochromocytoma defies the classic paradigm of RET oncogenic fusions
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    1. scibot 27 Jul 2022
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      DOI: 10.1016/j.xcrm.2022.100686

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    sciencedirect.com/science/article/pii/S2666379122002221
  3. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BACE-1 inhibition facilitates the transition from homeostatic microglia to DAM-1
    1
    1. scibot 06 Jul 2022
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      DOI: 10.1126/sciadv.abo1286

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    ncbi.nlm.nih.gov/pmc/articles/PMC9205595/
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neoadjuvant chemotherapy induces genomic and transcriptomic changes in ovarian cancer
    1
    1. scibot 06 Jul 2022
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      DOI: 10.1158/0008-5472.CAN-21-1467

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    ncbi.nlm.nih.gov/pmc/articles/PMC8936832/
  5. Jun 2022
  6. 52.53.155.43 52.53.155.43
    ajpendo.00293.2021-html.html
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    1. scibot 30 Jun 2022
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      DOI: 10.6084/m9.figshare.15180819.v8

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    52.53.155.43/d184932ca89ace2466b6122479ac9be348421b7e/ajpendo.00293.2021-html.html
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Differential effects of excess high-fructose corn syrup on the DNA methylation of hippocampal neurotrophic factor in childhood and adolescence
    1
    1. scibot 22 Jun 2022
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      DOI: 10.1371/journal.pone.0270144

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    ncbi.nlm.nih.gov/pmc/articles/PMC9205497/
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Intermittent Theta Burst Stimulation Ameliorates Cognitive Deficit and Attenuates Neuroinflammation via PI3K/Akt/mTOR Signaling Pathway in Alzheimer’s-Like Disease Model
    1
    1. scibot 15 Jun 2022
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      DOI: 10.3389/fnagi.2022.889983

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    ncbi.nlm.nih.gov/pmc/articles/PMC9152158/
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    MiR-690 treatment causes decreased fibrosis and steatosis and restores specific Kupffer cell functions in NASH
    1
    1. scibot 15 Jun 2022
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      DOI: 10.1016/j.cmet.2022.05.008

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    sciencedirect.com/science/article/pii/S1550413122001905
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    MASTL is enriched in cancerous and pluripotent stem cells and influences OCT1/OCT4 levels
    1
    1. scibot 15 Jun 2022
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      DOI: 10.1016/j.isci.2022.104459

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    sciencedirect.com/science/article/pii/S2589004222007301
  11. aacrjournals.org aacrjournals.org
    Liver Endothelium Promotes HER3-mediated Cell Survival in Colorectal Cancer with Wild-type and Mutant KRAS
    1
    1. scibot 14 Jun 2022
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      DOI: 10.1158/1541-7786.MCR-21-0633

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    aacrjournals.org/mcr/article/20/6/996/699064/Liver-Endothelium-Promotes-HER3-Mediated-Cell
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    The focal adhesion protein β-parvin controls cardiomyocyte shape and sarcomere assembly in response to mechanical load
    1
    1. scibot 10 Jun 2022
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      DOI: 10.1016/j.cub.2022.05.047

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    sciencedirect.com/science/article/pii/S0960982222008508
  13. www.sciencedirect.com www.sciencedirect.com
    Active APPL1 sequestration by Plasmodium favors liver-stage development
    1
    1. scibot 03 Jun 2022
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      DOI: 10.1016/j.celrep.2022.110886

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    sciencedirect.com/science/article/pii/S2211124722006611
  14. academic.oup.com academic.oup.com
    Influence of maternal exercise on glucose and lipid metabolism in offspring stem cells: ENHANCED by Mom
    1
    1. scibot 03 Jun 2022
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      DOI: 10.1210/clinem/dgac270

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    academic.oup.com/jcem/advance-article/doi/10.1210/clinem/dgac270/6577152
  15. Apr 2022
  16. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
    1
    1. scibot 28 Apr 2022
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      DOI: 10.1111/bph.15849

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15849
  17. www.sciencedirect.com www.sciencedirect.com
    Tissue remodeling by an opportunistic pathogen triggers allergic inflammation
    1
    1. scibot 28 Apr 2022
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      DOI: 10.1016/j.immuni.2022.04.001

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    sciencedirect.com/science/article/pii/S1074761322001728
  18. www.sciencedirect.com www.sciencedirect.com
    Cerebroprotein hydrolysate injection is involved in promoting long-term angiogenesis, vessel diameter and density after cerebral ischemia in mice
    1
    1. scibot 28 Apr 2022
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      DOI: 10.1016/j.lfs.2022.120568

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    sciencedirect.com/science/article/pii/S0024320522002685
  19. www.sciencedirect.com www.sciencedirect.com
    Betacellulin promotes tumor development and EGFR mutant lung cancer growth by stimulating the EGFR pathway and suppressing apoptosis
    1
    1. scibot 26 Apr 2022
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      DOI: 10.1016/j.isci.2022.104211

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    sciencedirect.com/science/article/pii/S2589004222004813
  20. link.springer.com link.springer.com
    Energetic metabolic reprogramming in Jurkat DFF40-deficient cancer cells
    1
    1. scibot 26 Apr 2022
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      DOI: 10.1007/s11010-022-04433-0

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    link.springer.com/article/10.1007/s11010-022-04433-0
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lack of Tgfbr1 and Acvr1b synergistically stimulates myofibre hypertrophy and accelerates muscle regeneration
    1
    1. scibot 14 Apr 2022
      RRID:AB_329825

      DOI: 10.7554/eLife.77610

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    ncbi.nlm.nih.gov/pmc/articles/PMC9005187/
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Calcineurin/NFATc2 and PI3K/AKT signaling maintains β-cell identity and function during metabolic and inflammatory stress
    1
    1. scibot 08 Apr 2022
      RRID:AB_329825

      DOI: 10.1016/j.isci.2022.104125

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    ncbi.nlm.nih.gov/pmc/articles/PMC8983383/
  23. Mar 2022
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR/Cas9 Screens Reveal Epstein-Barr Virus Transformed B-Cell Host Dependency Factors
    1
    1. scibot 26 Mar 2022
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      DOI: 10.1016/j.chom.2017.04.005

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    ncbi.nlm.nih.gov/pmc/articles/PMC8938989/
  25. www.sciencedirect.com www.sciencedirect.com
    Procr functions as a signaling receptor and is essential for the maintenance and self-renewal of mammary stem cells
    1
    1. scibot 23 Mar 2022
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      DOI: 10.1016/j.celrep.2022.110548

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    sciencedirect.com/science/article/pii/S2211124722002893
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Proanthocyanidins Inhibit the Transmission of Spinal Pain Information Through a Presynaptic Mechanism in a Mouse Inflammatory Pain Model
    1
    1. scibot 04 Mar 2022
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      DOI: 10.3389/fnins.2021.804722

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    ncbi.nlm.nih.gov/pmc/articles/PMC8850919/
  27. Feb 2022
  28. www.sciencedirect.com www.sciencedirect.com
    Thyroid hormone regulates glutamine metabolism and anaplerotic fluxes by inducing mitochondrial glutamate aminotransferase GPT2
    1
    1. scibot 23 Feb 2022
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      DOI: 10.1016/j.celrep.2022.110409

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    sciencedirect.com/science/article/pii/S2211124722001334
  29. www.sciencedirect.com www.sciencedirect.com
    Deletion of RNF186 expression suppresses diet-induced hepatic steatosis by regulating insulin activity
    1
    1. scibot 13 Feb 2022
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      DOI: 10.1016/j.isci.2022.103859

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    sciencedirect.com/science/article/pii/S2589004222001298
  30. www.sciencedirect.com www.sciencedirect.com
    Stanniocalcin2 inhibits the epithelial-mesenchymal transition and invasion of trophoblasts via activation of autophagy under high-glucose conditions
    1
    1. scibot 13 Feb 2022
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      DOI: 10.1016/j.mce.2022.111598

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    sciencedirect.com/science/article/pii/S0303720722000454
  31. www.sciencedirect.com www.sciencedirect.com
    Identification of the nucleotide-free state as a therapeutic vulnerability for inhibition of selected oncogenic RAS mutants
    2
    1. scibot 11 Feb 2022
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      DOI: 10.1016/j.celrep.2022.110322

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    2. scibot 09 Feb 2022
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      DOI: 10.1016/j.celrep.2022.110322

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    sciencedirect.com/science/article/pii/S221112472200033X
  32. www.sciencedirect.com www.sciencedirect.com
    Fungal mycobiome drives IL-33 secretion and type 2 immunity in pancreatic cancer
    1
    1. scibot 04 Feb 2022
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      DOI: 10.1016/j.ccell.2022.01.003

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    sciencedirect.com/science/article/pii/S1535610822000058
  33. www.sciencedirect.com www.sciencedirect.com
    Hypothalamic pregnenolone mediates recognition memory in the context of metabolic disorders
    1
    1. scibot 02 Feb 2022
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      DOI: 10.1016/j.cmet.2021.12.023

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    sciencedirect.com/science/article/pii/S1550413121006896
  34. www.nature.com www.nature.com
    Activating JAK-mutations confer resistance to FLT3 kinase inhibitors in FLT3-ITD positive AML in vitro and in vivo
    1
    1. scibot 01 Feb 2022
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      DOI: 10.1038/s41375-020-01077-1

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    nature.com/articles/s41375-020-01077-1
  35. Jan 2022
  36. link.springer.com link.springer.com
    Histone acetyltransferase NAA40 modulates acetyl-CoA levels and lipid synthesis
    1
    1. scibot 22 Jan 2022
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      DOI: 10.1186/s12915-021-01225-8

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    link.springer.com/article/10.1186/s12915-021-01225-8
  37. link.springer.com link.springer.com
    Involvement of FoxO1, Sp1, and Nrf2 in Upregulation of Negative Regulator of ROS by 15d-PGJ2 Attenuates H2O2-Induced IL-6 Expression in Rat Brain Astrocytes
    1
    1. scibot 11 Jan 2022
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      DOI: 10.1007/s12640-020-00318-6

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    link.springer.com/article/10.1007/s12640-020-00318-6
  38. link.springer.com link.springer.com
    PI3K inhibition by BKM120 results in anti-proliferative effects on corticotroph tumor cells
    1
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      DOI: 10.1007/s40618-021-01735-w

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    link.springer.com/article/10.1007/s40618-021-01735-w
  39. Dec 2021
  40. www.sciencedirect.com www.sciencedirect.com
    RhoA within myofibers controls satellite cell microenvironment to allow hypertrophic growth
    1
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      DOI: 10.1016/j.isci.2021.103616

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    sciencedirect.com/science/article/pii/S2589004221015868
  41. www.sciencedirect.com www.sciencedirect.com
    Engineering immunoproteasome-expressing mesenchymal stromal cells: A potent cellular vaccine for lymphoma and melanoma in mice
    1
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      DOI: 10.1016/j.xcrm.2021.100455

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    sciencedirect.com/science/article/pii/S2666379121003232
  42. www.sciencedirect.com www.sciencedirect.com
    The imprinted Igf2-Igf2r axis is critical for matching placental microvasculature expansion to fetal growth
    1
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      DOI: 10.1016/j.devcel.2021.12.005

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    sciencedirect.com/science/article/pii/S1534580721009941
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRMP4-mediated fornix development involves Semaphorin-3E signaling pathway
    1
    1. scibot 22 Dec 2021
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      DOI: 10.7554/eLife.70361

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    ncbi.nlm.nih.gov/pmc/articles/PMC8683083/
  44. link.springer.com link.springer.com
    Ocimum basilicum but not Ocimum gratissimum present cytotoxic effects on human breast cancer cell line MCF-7, inducing apoptosis and triggering mTOR/Akt/p70S6K pathway
    1
    1. scibot 22 Dec 2021
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      DOI: 10.1007/s10863-018-9750-3

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    link.springer.com/article/10.1007/s10863-018-9750-3
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The spike protein of SARS-CoV-2 virus induces heme oxygenase-1: Pathophysiologic implications
    2
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      DOI: 10.1016/j.bbadis.2021.166322

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    2. scibot 15 Dec 2021
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      DOI: 10.1016/j.bbadis.2021.166322

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    ncbi.nlm.nih.gov/pmc/articles/PMC8669938/
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Aging Does Not Exacerbate Muscle Loss During Denervation and Lends Unique Muscle-Specific Atrophy Resistance With Akt Activation
    1
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      RRID:AB_329825

      DOI: 10.1111/jnc.14238

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  91. www.mdpi.com www.mdpi.com
    CRISPR/Cas9-Mediated Knock-Out of KrasG12D Mutated Pancreatic Cancer Cell Lines
    1
    1. scibot 02 Aug 2021
      RRID:AB_329825

      DOI: 10.3390/ijms20225706

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  92. academic.oup.com academic.oup.com
    Lithium Chloride Increases COX-2 Expression and PGE2 Production in a Human Granulosa-Lutein SVOG Cell Line Via a GSK-3β/β-Catenin Signaling Pathway
    1
    1. scibot 02 Aug 2021
      RRID:AB_329825

      DOI: 10.1210/en.2017-00287

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  93. elifesciences.org elifesciences.org
    PPM1H phosphatase counteracts LRRK2 signaling by selectively dephosphorylating Rab proteins
    1
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      RRID:AB_329825

      DOI: 10.7554/eLife.50416

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  94. Jul 2021
  95. www.jlr.org www.jlr.org
    Identification of ApoA4 as a sphingosine 1-phosphate chaperone in ApoM- and albumin-deficient mice
    1
    1. scibot 31 Jul 2021
      anti-phospho Akt

      DOI: 10.1194/jlr.RA119000277

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  96. www.sciencedirect.com www.sciencedirect.com
    Dysregulation of Mitochondrial Ca2+ Uptake and Sarcolemma Repair Underlie Muscle Weakness and Wasting in Patients and Mice Lacking MICU1
    1
    1. scibot 31 Jul 2021
      Rabbit anti-phospho-AKT (Ser473)

      DOI: 10.1016/j.celrep.2019.09.063

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  97. academic.oup.com academic.oup.com
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      RRID:AB_329825

      DOI: 10.1210/en.2018-00990

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  98. academic.oup.com academic.oup.com
    Intrinsic High Aerobic Capacity in Male Rats Protects Against Diet-Induced Insulin Resistance
    1
    1. scibot 31 Jul 2021
      RRID:AB_329825

      DOI: 10.1210/en.2019-00118

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  99. www.sciencedirect.com www.sciencedirect.com
    Regulation of the Elongation Phase of Protein Synthesis Enhances Translation Accuracy and Modulates Lifespan
    1
    1. scibot 31 Jul 2021
      RRID:AB_329825

      DOI: 10.1016/j.cub.2019.01.029

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  100. www.sciencedirect.com www.sciencedirect.com
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      RRID:AB_329825

      DOI: 10.1016/j.celrep.2019.02.014

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  101. academic.oup.com academic.oup.com
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      RRID:AB_329825

      DOI: 10.1210/en.2018-00531

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  102. www.sciencedirect.com www.sciencedirect.com
    12-Lipoxygenase Regulates Cold Adaptation and Glucose Metabolism by Producing the Omega-3 Lipid 12-HEPE from Brown Fat
    1
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      Phospho-Akt (Ser473)

      DOI: 10.1016/j.cmet.2019.07.001

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    sciencedirect.com/science/article/pii/S1550413119303742
  103. mbio.asm.org mbio.asm.org
    Pathogenic Escherichia coli Hijacks GTPase-Activated p21-Activated Kinase for Actin Pedestal Formation
    1
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      phospho-Akt [Ser473], 9271

      DOI: 10.1128/mBio.01876-19

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  104. www.sciencedirect.com www.sciencedirect.com
    Pro-Survival Lipid Sphingosine-1-Phosphate Metabolically Programs T Cells to Limit Anti-tumor Activity
    1
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      Mouse anti-Akt (pS473)

      DOI: 10.1016/j.celrep.2019.07.044

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  105. www.sciencedirect.com www.sciencedirect.com
    PI3K inhibitors protect against glucocorticoid-induced skin atrophy
    1
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      RRID:AB_329825

      DOI: 10.1016/j.ebiom.2019.01.055

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  106. academic.oup.com academic.oup.com
    Lack of Lrp5 Signaling in Osteoblasts Sensitizes Male Mice to Diet-Induced Disturbances in Glucose Metabolism
    2
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      AB_329825

      DOI: 10.1210/en.2017-00657

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    2. scibot 28 Jul 2021
      RRID:AB_329825

      DOI: 10.1210/en.2017-00657

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  107. academic.oup.com academic.oup.com
    Lithium Chloride Increases COX-2 Expression and PGE2 Production in a Human Granulosa-Lutein SVOG Cell Line Via a GSK-3β/β-Catenin Signaling Pathway
    2
    1. scibot 28 Jul 2021
      AB_329825

      DOI: 10.1210/en.2017-00287

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      RRID:AB_329825

      DOI: 10.1210/en.2017-00287

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  108. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling
    1
    1. scibot 27 Jul 2021
      RRID: AB_329825

      DOI: 10.1016/j.cels.2016.11.013

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  109. academic.oup.com academic.oup.com
    Low-Dose Dihydrotestosterone Drives Metabolic Dysfunction via Cytosolic and Nuclear Hepatic Androgen Receptor Mechanisms
    2
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      Phospho-AKTu00a0u00a0p-AKT (Ser473)u00a0Cell Signaling Technology, no. 9271u00a0Rabbit; polyclonalu00a0

      DOI: 10.1210/en.2016-1553

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      AB_329825

      DOI: 10.1210/en.2016-1553

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  110. press.endocrine.org press.endocrine.org
    Nervous System Expression of PPARγ and Mutant PPARγ Has Profound Effects on Metabolic Regulation and Brain Development: Endocrinology: Vol 157, No 11
    2
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      AB_329825

      DOI: 10.1210/en.2016-1524

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      9271; Cell Signaling Technology

      DOI: 10.1210/en.2016-1524

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  111. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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      RRID:AB_329825

      DOI: 10.1016/j.celrep.2018.09.065

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  112. www.sciencedirect.com www.sciencedirect.com
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      RRID:AB_329825

      DOI: 10.1016/j.celrep.2018.11.005

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  113. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    AhR ligand aminoflavone suppresses α6‐integrin–Src–Akt signaling to attenuate tamoxifen resistance in breast cancer cells
    1
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      RRID:AB_32928

      DOI: 10.1002/jcp.27013

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  114. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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      AB_329825

      DOI: 10.1210/en.2017-00738

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  115. europepmc.org europepmc.org
    A Novel Small Molecule GDNF Receptor RET Agonist, BT13, Promotes Neurite Growth from Sensory Neurons in Vitro and Attenuates Experimental Neuropathy in the Rat.
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      RRID:AB_329826

      DOI: 10.3389/fphar.2017.00365

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  116. www.sciencedirect.com www.sciencedirect.com
    Modulation of Akt vs Stat3 activity by the focal adhesion kinase in non-neoplastic mouse fibroblasts
    1
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      Cell-signalling technology Cat. #9271

      DOI: 10.1016/j.yexcr.2021.112731

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    sciencedirect.com/science/article/pii/S0014482721002639
  117. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Extracellular domain shedding of the ALK receptor mediates neuroblastoma cell migration
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      RRID:AB_329825

      DOI: 10.1016/j.celrep.2021.109363

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  118. www.sciencedirect.com www.sciencedirect.com
    Doxorubicin induces dysregulation of AMPA receptor and impairs hippocampal synaptic plasticity leading to learning and memory deficits
    1
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      AB_329825

      DOI: 10.1016/j.heliyon.2021.e07456

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  119. Jun 2021
  120. journals.physiology.org journals.physiology.org
    Pancreatic fat cells of humans with type 2 diabetes display reduced adipogenic and lipolytic activity | American Journal of Physiology-Cell Physiology
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      RRID:AB_329825

      DOI: 10.1152/ajpcell.00595.2020

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  121. academic.oup.com academic.oup.com
    Endothelial insulin receptors promote VEGF-A signaling via ERK1/2 and sprouting angiogenesis
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      RRID:AB_329825

      DOI: 10.1210/endocr/bqab104

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  122. academic.oup.com academic.oup.com
    CX3CL1–CX3CR1 signalling deficiency exacerbates obesity-induced inflammation and insulin resistance in male mice
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      RRID:AB_329825

      DOI: 10.1210/endocr/bqab064

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  123. journals.physiology.org journals.physiology.org
    Pancreatic fat cells of humans with type 2 diabetes display reduced adipogenic and lipolytic activity
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      RRID:AB_329825

      DOI: 10.1152/ajpcell.00595.2020

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  124. www.sciencedirect.com www.sciencedirect.com
    Co-occurring gain-of-function mutations in HER2 and HER3 modulate HER2/HER3 activation, oncogenesis, and HER2 inhibitor sensitivity
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      RRID:AB_329825

      DOI: 10.1016/j.ccell.2021.06.001

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    The AML microenvironment catalyzes a stepwise evolution to gilteritinib resistance
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      DOI: 10.1016/j.ccell.2021.06.003

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  126. www.frontiersin.org www.frontiersin.org
    Promotion of Bone Lesions Through the Myeloma Integrin α6-Mediated Osteolytic Signaling
    1
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      AB_329825

      DOI: 10.3389/fonc.2021.692190

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  127. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Glutamine regulates ovarian cancer cell migration and invasion through ETS1
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      RRID:AB_329825

      DOI: 10.1016/j.heliyon.2021.e07064

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  128. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Palmitic acid induces insulin resistance by a mechanism associated with energy metabolism and calcium entry in neuronal cells
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      DOI: 10.1096/fj.202100243R

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  129. www.sciencedirect.com www.sciencedirect.com
    The CD44/COL17A1 pathway promotes the formation of multilayered, transformed epithelia
    1
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      RRID:AB_329825

      DOI: 10.1016/j.cub.2021.04.078

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  130. May 2021
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    PD-L1 recruits phospholipase C and enhances tumorigenicity of lung tumors harboring mutant forms of EGFR
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    The PP2A-Integrator-CDK9 axis fine-tunes transcription and can be targeted therapeutically in cancer
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  133. cancerres.aacrjournals.org cancerres.aacrjournals.org
    Integrated Screens Identify CDK1 as a Therapeutic Target in Advanced Gastrointestinal Stromal Tumors
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    The selective lipoprotein-associated phospholipase A2 inhibitor darapladib triggers irreversible actions on glioma cell apoptosis and mitochondrial dysfunction
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    Pathologic HIF1α signaling drives adipose progenitor dysfunction in obesity
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    DNA Damage Promotes TMPRSS2-ERG Oncoprotein Destruction and Prostate Cancer Suppression via Signaling Converged by GSK3β and WEE1
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    Insulin- and Lipopolysaccharide-Mediated Signaling in Adipose Tissue Macrophages Regulates Postprandial Glycemia through Akt-mTOR Activation
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    HectD1 controls hematopoietic stem cell regeneration by coordinating ribosome assembly and protein synthesis
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    Small Extracellular Vesicle Regulation of Mitochondrial Dynamics Reprograms a Hypoxic Tumor Microenvironment
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  140. Apr 2021
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    Caloric Restriction Promotes Immunometabolic Reprogramming Leading to Protection from Tuberculosis
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    MiR-690, an exosomal-derived miRNA from M2-polarized macrophages, improves insulin sensitivity in obese mice
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    Functional Genomics Identifies Metabolic Vulnerabilities in Pancreatic Cancer
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    Central Ceramide Signaling Mediates Obesity-Induced Precocious Puberty
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    Glutamine Metabolism Controls Stem Cell Fate Reversibility and Long-Term Maintenance in the Hair Follicle
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    Combined Omics Approaches Reveal the Roles of Non-canonical WNT7B Signaling and YY1 in the Proliferation of Human Pancreatic Progenitor Cells
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    Cancer cells escape autophagy inhibition via NRF2-induced macropinocytosis
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    Reduced Mitochondrial Apoptotic Priming Drives Resistance to BH3 Mimetics in Acute Myeloid Leukemia
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    Developmental partitioning of SYK and ZAP70 prevents autoimmunity and cancer
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    Gene editing and synthetically accessible inhibitors reveal role for TPC2 in HCC cell proliferation and tumor growth
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  151. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Triggering Receptor Expressed on Myeloid Cells-2 (TREM2) Interacts With Colony-Stimulating Factor 1 Receptor (CSF1R) but Is Not Necessary for CSF1/CSF1R-Mediated Microglial Survival
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  152. Mar 2021
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    Hericium erinaceus mycelium and its small bioactive compounds promote oligodendrocyte maturation with an increase in myelin basic protein
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    Transcriptional programming drives Ibrutinib-resistance evolution in mantle cell lymphoma
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  155. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  156. academic.oup.com academic.oup.com
    CXCR4 signaling at the fetal-maternal interface may drive inflammation and syncytia formation during ovine pregnancy †
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    An Embryonic Diapause-like Adaptation with Suppressed Myc Activity Enables Tumor Treatment Persistence
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  158. Feb 2021
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    Alternative signaling pathways from IGF1 or Insulin to Akt activation and Foxo1 nuclear efflux in adult skeletal muscle fibers
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      phospho-AKT Ser473

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    Selective targeting of the androgen receptor-DNA binding domain by the novel antiandrogen SBF-1 and inhibition of the growth of prostate cancer cells
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    PD-L1 Reverse Signaling in Dermal Dendritic Cells Promotes Dendritic Cell Migration Required for Skin Immunity
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  162. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    The insulin‐sensitizing effect of a single exercise bout is similar in type I and type II human muscle fibres
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    ErbB3 is a critical regulator of cytoskeletal dynamics in brain microvascular endothelial cells: Implications for vascular remodeling and blood-brain-barrier modulation - Limin Wu, Mohammad R Islam, Janice Lee, Hajime Takase, Shuzhen Guo, Allison M Andrews, Tetyana P Buzhdygan, Justin Mathew, Wenlu Li, Ken Arai, Eng H Lo, Servio H Ramirez, Josephine Lok, 2021
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  164. www.cell.com www.cell.com
    Mitochondrial Threonyl-tRNA Synthetase TARS2 Is Required for Threonine-Sensitive mTORC1 Activation
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    Inflammation-driven senescence-associated secretory phenotype in cancer-associated fibroblasts enhances peritoneal dissemination
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  166. onlinelibrary.wiley.com onlinelibrary.wiley.com
    LncRNA RP6‐65G23.1 accelerates proliferation and inhibits apoptosis via p‐ERK1/2/p‐AKT signaling pathway on keratinocytes
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  167. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Reduced Na+K+‐ATPase activity may reduce amino acid uptake in IUGR fetal sheep muscle despite unchanged ex vivo amino acid transporter activity
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      DOI: 10.1113/JP278933

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    Synergistic growth inhibition mediated by dual PI3K/mTOR pathway targeting and genetic or direct pharmacological AKT inhibition in human glioblastoma models
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    onlinelibrary.wiley.com/doi/10.1111/jnc.14899
  169. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Insulin‐stimulated glucose uptake partly relies on p21‐activated kinase 2 (PAK2), but not PAK1, in mouse skeletal muscle
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      AB_329

      DOI: 10.1113/JP280294

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  170. www.sciencedirect.com www.sciencedirect.com
    An acetyl-histone vulnerability in PI3K/AKT inhibition-resistant cancers is targetable by both BET and HDAC inhibitors
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      DOI: 10.1016/j.celrep.2021.108744

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    sciencedirect.com/science/article/pii/S2211124721000577
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    ARHGEF3 regulates skeletal muscle regeneration and strength through autophagy
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      pSer473-Akt

      DOI: 10.1016/j.celrep.2021.108731

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    sciencedirect.com/science/article/pii/S2211124721000449
  172. Jan 2021
  173. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A feed-forward regulatory loop in adipose tissue promotes signaling by the hepatokine FGF21
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  175. Dec 2020
  176. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Autoimmune activation of the GnRH receptor induces insulin resistance independent of obesity in a female rat model
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    Staphylococcus aureus Panton‐Valentine Leukocidin triggers an alternative NETosis process targeting mitochondria
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    Hetero-oligomerization of Rho and Ras GTPases Connects GPCR Activation to mTORC2-AKT Signaling
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  179. Nov 2020
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    TSPAN1: A Novel Protein Involved in Head and Neck Squamous Cell Carcinoma Chemoresistance
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  181. Oct 2020
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    Enhancer Reprogramming Confers Dependence on Glycolysis and IGF Signaling in KMT2D Mutant Melanoma
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    A Small-Molecule Approach to Restore a Slow-Oxidative Phenotype and Defective CaMKIIβ Signaling in Limb Girdle Muscular Dystrophy
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    Phosphorylation of eIF2α promotes Schwann cell differentiation and myelination in CMT1B mice with activated UPR
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    Mechanisms by which membrane and nuclear ER alpha inhibit adipogenesis in cells isolated from female mice
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    TGFβR-SMAD3 Signaling Induces Resistance to PARP Inhibitors in the Bone Marrow Microenvironment
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    MED19 Regulates Adipogenesis and Maintenance of White Adipose Tissue Mass by Mediating PPARγ-Dependent Gene Expression
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  188. Sep 2020
  189. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Maternal exercise attenuates the lower skeletal muscle glucose uptake and insulin secretion caused by paternal obesity in female adult rat offspring
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    Metabolic Imaging Detects Resistance to PI3Kα Inhibition Mediated by Persistent FOXM1 Expression in ER+ Breast Cancer
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    HSP90 Inhibitor, 17-DMAG, Alone and in Combination with Lapatinib Attenuates Acquired Lapatinib-Resistance in ER-positive, HER2-Overexpressing Breast Cancer Cell Line
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  192. diabetes.diabetesjournals.org diabetes.diabetesjournals.org
    A Single Bout of One-legged Exercise to Local Exhaustion Decreases Insulin Action in Non-exercised Muscle Leading to Decreased Whole-body Insulin Action
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    Enhanced Akt/GSK‐3β/CREB signaling mediates the anti‐inflammatory actions of mGluR5 positive allosteric modulators in microglia and following traumatic brain injury in male mice
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    Enhancer-Driven lncRNA BDNF-AS Induces Endocrine Resistance and Malignant Progression of Breast Cancer through the RNH1/TRIM21/mTOR Cascade
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    Pharmacological targeting of α3β4 nicotinic receptors improves peripheral insulin sensitivity in mice with diet-induced obesity
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    High‐frequency transcranial magnetic stimulation protects APP/PS1 mice against Alzheimer’s disease progress by reducing APOE and enhancing autophagy
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    The endothelial barrier is not rate-limiting to insulin action in the myocardium of male mice
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    Molecular Stressors Engender Protein Connectivity Dysfunction through Aberrant N-Glycosylation of a Chaperone
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    Low-Dose Vertical Inhibition of the RAF-MEK-ERK Cascade Causes Apoptotic Death of KRAS Mutant Cancers
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    Differential Signaling Mediated by ApoE2, ApoE3, and ApoE4 in Human Neurons Parallels Alzheimer's Disease Risk
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    Topological Adaptation of Transmembrane Domains to the Force-Modulated Lipid Bilayer Is a Basis of Sensing Mechanical Force
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    Cancer causes metabolic perturbations associated with reduced insulin-stimulated glucose uptake in peripheral tissues and impaired muscle microvascular perfusion
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    Late Endosomes Act as mRNA Translation Platforms and Sustain Mitochondria in Axons
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    Effects of acute aerobic, resistance and combined exercises on 24-h glucose variability and skeletal muscle signalling responses in type 1 diabetics
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    Acute pharmacological inhibition of matrix metalloproteinase‐9 activity during development restores perineuronal net formation and normalizes auditory processing in Fmr1 KO mice
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    DPP-4 inhibition with anagliptin reduces lipotoxicity-induced insulin resistance and steatohepatitis in male mice
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    Tau Reduction Prevents Key Features of Autism in Mouse Models
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    Translational Physiology: Insulin signaling displayed a differential tissue-specific response to low-dose dihydrotestosterone in female mice
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      SciCrunch record: RRID:AB_329825

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      RRIDCUR:Validated RRID:AB_329825
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    ncbi.nlm.nih.gov/pmc/articles/PMC5966754/