627 Matching Annotations
  1. Aug 2025
  2. 52.53.155.43 52.53.155.43
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    Type I interferon signaling promotes kainic acid-induced seizures through mTOR activation
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    sciencedirect.com/science/article/pii/S0028390825003429
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    Succinate preserves CD8+ T cell fitness to augment antitumor immunity
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    sciencedirect.com/science/article/pii/S1074761325003267
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    Targeting the MYC oncogene with a selective bi-steric mTORC1 inhibitor elicits tumor regression in MYC-driven cancers
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    sciencedirect.com/science/article/pii/S2451945625002272
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    Tumor-resident probiotic Clostridium butyricum improves aPD-1 efficacy in colorectal cancer models by inhibiting IL-6-mediated immunosuppression
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    Methylphenidate triggers retinal oxidative stress and mitochondrial dysfunction under physiological conditions but has beneficial effects in inflammatory settings
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  8. Jul 2025
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    NEDD4 Promotes Sertoli Cell Proliferation and Adult Leydig Cell Differentiation in the Murine Testis
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    Inhibitory Effects of Vandetanib on Catecholamine Synthesis in Rat Pheochromocytoma PC12 Cells
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    Pantothenate protects against obesity via brown adipose tissue activation
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    A Rac-specific competitive inhibitor of guanine nucleotide binding reduces metastasis in triple-negative breast cancer
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    Interconnections of insulin/IGF-1 signaling and autophagy abnormalities in Alzheimer's disease
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    The immune response against cancer is modulated by stromal cell fibronectin
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  15. Jun 2025
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    PTEN neddylation aggravates CDK4/6 inhibitor resistance in breast cancer
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    FGF21 promotes longevity in diet-induced obesity through metabolic benefits independent of growth suppression
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    CSF1R+ myeloid-monocytic cells drive CAR-T cell resistance in aggressive B cell lymphoma
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    Insulin- and exercise-induced phosphoproteomics of human skeletal muscle identify REPS1 as a regulator of muscle glucose uptake
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    Regulation of Rho guanine nucleotide exchange factor 3 by phosphorylation in the PH domain
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    Deficiency in N-cadherin-Akt3 signaling impairs the blood-brain barrier
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    EGFR phosphorylates DNAJB1 to suppress α-synuclein aggregation in Parkinson’s disease
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  25. May 2025
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    Impact of ATF6 deletion on the embryonic brain development
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    Heterozygous Kmt2d loss diminishes enhancers to render medulloblastoma cells vulnerable to combinatory inhibition of LSD1 and OXPHOS
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    Growth Hormone Promotes Lipolysis and Impairs Insulin Sensitivity by Activating the ERK/HSL Signaling Pathway in Bovine Adipocytes
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  30. Apr 2025
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    PI3K/AKT signaling mediates stress-inducible amyloid formation through c-Myc
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    Time Release Ion Matrix Regenerates Dystrophic Skeletal Muscle
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  33. 52.53.155.43 52.53.155.43
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    Cell adhesion molecule protocadherin-γC5 ameliorates Aβ plaque pathogenesis by modulating astrocyte function in Alzheimer’s disease
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  35. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Growth Hormone-Releasing Hormone Antagonists Increase Radiosensitivity in Non-Small Cell Lung Cancer Cells
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  36. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Central Downregulation of S-Resistin Alleviates Inflammation in EWAT and Liver and Prevents Adipocyte Hypertrophy
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    Perillartine protects against metabolic associated fatty liver in high-fat diet-induced obese mice
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    PLK1 blockade enhances the anti-tumor effect of MAPK inhibition in pancreatic ductal adenocarcinoma
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    HEXA-FC protein therapy increases skeletal muscle glucose uptake and improves glycaemic control in mice with insulin resistance and in a mouse model of type 2 diabetes
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    Injured tubular epithelia-derived CCN1 promotes the mobilization of fibroblasts toward injury sites after kidney injury
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  42. Mar 2025
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    Maternal progesterone and adipose mPRε in pregnancy regulate the embryonic nutritional state
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    Realigned transsulfuration drives BRAF-V600E-targeted therapy resistance in melanoma
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    Hepatic stellate cells regulate liver fatty acid utilization via plasmalemma vesicle-associated protein
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  47. Feb 2025
  48. link.springer.com link.springer.com
    AXL promotes lymphangiogenesis by amplifying VEGF-C-mediated AKT pathway
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  49. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Dietary nitrate supplementation mitigates age-related changes at the neuromuscular junction in mice
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    Leptin enhances the intracellular thyroid hormone activation in skeletal muscle to boost energy balance
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  51. dx.doi.org dx.doi.org
    Progesterone Receptor Signaling Promotes Cancer Associated Fibroblast Mediated Tumorigenicity in ER+ Breast Cancer
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    dx.doi.org/10.1210/endocr/bqae092
  52. aacrjournals.org aacrjournals.org
    C/EBPa confers dependence to fatty acid anabolic pathways and vulnerability to lipid oxidative stress-induced ferroptosis in FLT3-mutant leukemia
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  53. 52.53.155.43 52.53.155.43
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    Cellular deconstruction of the human skeletal muscle microenvironment identifies an exercise-induced histaminergic crosstalk
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  56. 52.53.155.43 52.53.155.43
    PI3K/AKT Signaling Mediates Stress-Inducible Amyloid Aggregation Through c-myc
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    A methyltransferase-independent role for METTL1 in tRNA aminoacylation and oncogenic transformation
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  58. Jan 2025
  59. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Anandamide Inhibits Vascular Smooth Muscle Migration, Endothelial Adhesion Protein Expression and Monocyte Adhesion of Human Coronary Artery Cells
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    Paradoxical dominant negative activity of an immunodeficiency-associated activating PIK3R1 variant
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    pmc.ncbi.nlm.nih.gov/articles/PMC11750134/
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    Neuraminidase 1 regulates neuropathogenesis by governing the cellular state of microglia via modulation of Trem2 sialylation
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    mTORC1 regulates the pyrimidine salvage pathway by controlling UCK2 turnover via the CTLH-WDR26 E3 ligase
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  64. Dec 2024
  65. www.cell.com www.cell.com
    Adipocyte-derived ferroptotic signaling mitigates obesity
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    cell.com/cell-metabolism/abstract/S1550-4131(24)00456-X
  66. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Antibody-Drug Conjugates Targeting the EGFR Ligand Epiregulin Elicit Robust Anti-Tumor Activity in Colorectal Cancer
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    Genomic and transcriptomic landscape of human gastrointestinal stromal tumors
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  68. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  69. www.sciencedirect.com www.sciencedirect.com
    SPTLC3 regulates plasma membrane sphingolipid composition to facilitate hepatic gluconeogenesis
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  70. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Induced neural stem cells regulate microglial activation through Akt-mediated upregulation of CXCR4 and Crry in a mouse model of closed head injury
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    Impacts of APOE-ε4 and exercise training on brain microvascular endothelial cell barrier function and metabolism
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  72. bmcmedicine.biomedcentral.com bmcmedicine.biomedcentral.com
    Multiomics profiling of DNA methylation, microRNA, and mRNA in skeletal muscle from monozygotic twin pairs discordant for type 2 diabetes identifies dysregulated genes controlling metabolism
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    bmcmedicine.biomedcentral.com/articles/10.1186/s12916-024-03789-y
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    CD97 maintains tumorigenicity of glioblastoma stem cells via mTORC2 signaling and is targeted by CAR Th9 cells
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  74. www.biorxiv.org www.biorxiv.org
    Epstein-Barr viral product-containing exosome facilitates LIF-associated immunosuppressive polarization of macrophage in nasopharyngeal carcinoma
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    biorxiv.org/content/10.1101/2024.11.25.625317v1
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    Therapeutic induction of ferroptosis in tumors using PD-L1 targeting antibody nanogel conjugates
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    DEP-1 is a brain insulin receptor phosphatase that prevents the simultaneous activation of counteracting metabolic pathways
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  77. Nov 2024
  78. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PAPP-A as a Potential Target in Thyroid Eye Disease
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    Opposing roles for AMPK in regulating distinct mitophagy pathways
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  80. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    High fat diet induced hepatic insulin resistance per se attenuates murine de novo lipogenesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11550620/
  81. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Insulin Mediates Lipopolysaccharide-Induced Inflammatory Responses and Oxidative Stress in BV2 Microglia
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  82. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Bidirectional signals generated by Siglec-7 and its crucial ligand tri-sialylated T to escape of cancer cells from immune surveillance
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  83. Oct 2024
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    Midkine as a driver of age-related changes and increase in mammary tumorigenesis
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    Voluntary exercise suppresses inflammation and improves insulin resistance in the arcuate nucleus and ventral tegmental area in mice on a high-fat diet
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  86. Sep 2024
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    Zdhhc1- and Zdhhc2-mediated Gpm6a palmitoylation is essential for maintenance of mammary stem cell activity
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    PI3K isoform-selective inhibition in neuron-specific PTEN-deficient mice rescues molecular defects and reduces epilepsy-associated phenotypes
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    Amino alkynylisoquinoline and alkynylnaphthyridine compounds potently inhibit acute myeloid leukemia proliferation in mice
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    Overexpression of Igf2-derived Mir483 inhibits Igf1 expression and leads to developmental growth restriction and metabolic dysfunction in mice
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  91. www.nature.com www.nature.com
    Defective N-glycosylation of IL6 induces metastasis and tyrosine kinase inhibitor resistance in lung cancer
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    nature.com/articles/s41467-024-51831-7
  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PlexinB1 Inactivation Reprograms Immune Cells in the Tumor Microenvironment, Inhibiting Breast Cancer Growth and Metastatic Dissemination
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    ncbi.nlm.nih.gov/pmc/articles/PMC11369622/
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    IGF1 promotes human myotube differentiation toward a mature metabolic and contractile phenotype
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  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Anti-HDGF antibody targets EGFR tyrosine kinase inhibitor-tolerant cells in NSCLC patient-derived xenografts
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