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  1. Feb 2023
  2. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Combination therapy with bevacizumab and a CCR2 inhibitor for human ovarian cancer: An in vivo validation study
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    1. scibot 23 Feb 2023
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      DOI: 10.1002/cam4.5674

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    onlinelibrary.wiley.com/doi/10.1002/cam4.5674
  3. 52.53.155.43 52.53.155.43
    cd-22-0376-html.html
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    1. scibot 17 Feb 2023
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      DOI: 10.1158/2159-8290.cd-22-0376

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    GPR143 controls ESCRT-dependent exosome biogenesis and promotes cancer metastasis
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    1. scibot 17 Feb 2023
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      DOI: 10.1016/j.devcel.2023.01.006

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    sciencedirect.com/science/article/pii/S1534580723000370
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    CD70 is a therapeutic target upregulated in EMT-associated EGFR tyrosine kinase inhibitor resistance
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    1. scibot 16 Feb 2023
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    sciencedirect.com/science/article/pii/S1535610823000077
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    Development of a bispecific DNA-aptamer-based lysosome-targeting chimera for HER2 protein degradation
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    1. scibot 16 Feb 2023
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      DOI: 10.1016/j.xcrp.2023.101296

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    sciencedirect.com/science/article/pii/S2666386423000553
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    Conservation of the PBL-RBOH immune module in land plants
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    sciencedirect.com/science/article/pii/S0960982223000842
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    CXXC5 Mediates DHT-Induced Androgenetic Alopecia via PGD2
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    1. scibot 15 Feb 2023
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      DOI: 10.3390/cells12040555

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  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    KRAS Mutants Upregulate Integrin β4 to Promote Invasion and Metastasis in Colorectal Cancer
    1
    1. scibot 09 Feb 2023
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      DOI: 10.1158/1541-7786.MCR-21-0994

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    IDH2 and TET2 mutations synergize to modulate T Follicular Helper cell functional interactionwith the AITL microenvironment
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    1. scibot 03 Feb 2023
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    sciencedirect.com/science/article/pii/S153561082300003X
  11. Jan 2023
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Interleukin 11 confers resistance to dextran sulfate sodium-induced colitis in mice
    1
    1. scibot 25 Jan 2023
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      DOI: 10.1016/j.isci.2023.105934

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    ncbi.nlm.nih.gov/pmc/articles/PMC9852934/
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    Plakophilin 3 facilitates G1/S phase transition and enhances proliferation by capturing RB protein in the cytoplasm and promoting EGFR signaling
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    1. scibot 24 Jan 2023
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      DOI: 10.1016/j.celrep.2023.112031

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    sciencedirect.com/science/article/pii/S2211124723000426
  14. academic.oup.com academic.oup.com
    Suppression of Insulin Receptor Substrate 1 Inhibits Breast Cancer Growth In Vitro and in Female Athymic Mice
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    1. scibot 21 Jan 2023
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      DOI: 10.1210/endocr/bqac214

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    academic.oup.com/endo/article/164/3/bqac214/6969391
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    Targeting KRAS-mutant stomach/colorectal tumors by disrupting the ERK2-p53 complex
    1
    1. scibot 19 Jan 2023
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      DOI: 10.1016/j.celrep.2022.111972

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    sciencedirect.com/science/article/pii/S2211124722018769
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Thrombin increases the expression of cholesterol 25-hydroxylase in rat astrocytes after spinal cord injury
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    1. scibot 18 Jan 2023
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      DOI: 10.4103/1673-5374.357905

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    ncbi.nlm.nih.gov/pmc/articles/PMC9838143/
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Argon preconditioning protects neuronal cells with a Toll-like receptor-mediated effect
    1
    1. scibot 18 Jan 2023
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      DOI: 10.4103/1673-5374.355978

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    ncbi.nlm.nih.gov/pmc/articles/PMC9838174/
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Novel Calcium-Binding Ablating Mutations Induce Constitutive RET Activity and Drive Tumorigenesis
    1
    1. scibot 12 Jan 2023
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      DOI: 10.1158/0008-5472.CAN-22-0834

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  19. link.springer.com link.springer.com
    Cyclooxygenase-2 activates EGFR–ERK1/2 pathway via PGE2-mediated ADAM-17 signaling in testosterone-induced benign prostatic hyperplasia
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    1. scibot 04 Jan 2023
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      DOI: 10.1007/s10787-022-01123-7

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    link.springer.com/article/10.1007/s10787-022-01123-7
  20. Dec 2022
  21. www.mdpi.com www.mdpi.com
    Neuroprotective and Anti-Neuroinflammatory Properties of Vignae Radiatae Semen in Neuronal HT22 and Microglial BV2 Cell Lines
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    1. scibot 22 Dec 2022
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      DOI: 10.3390/nu14245265

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    mdpi.com/2072-6643/14/24/5265
  22. www.mdpi.com www.mdpi.com
    Human PSEN1 Mutant Glia Improve Spatial Learning and Memory in Aged Mice
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    1. scibot 22 Dec 2022
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      DOI: 10.3390/cells11244116

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  23. www.sciencedirect.com www.sciencedirect.com
    KMT2D deficiency drives lung squamous cell carcinoma and hypersensitivity to RTK-RAS inhibition
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    1. scibot 17 Dec 2022
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      DOI: 10.1016/j.ccell.2022.11.015

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    sciencedirect.com/science/article/pii/S1535610822005621
  24. www.sciencedirect.com www.sciencedirect.com
    Cav1.3 L-type Ca2+ channel-activated CaMKII/ERK2 pathway in the ventral tegmental area is required for cocaine conditioned place preference
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    1. scibot 06 Dec 2022
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      DOI: 10.1016/j.neuropharm.2022.109368

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    sciencedirect.com/science/article/pii/S0028390822004270
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The κ-opioid receptor-induced autophagy is implicated in stress-driven synaptic alterations
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    1. scibot 02 Dec 2022
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      DOI: 10.3389/fnmol.2022.1039135

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    ncbi.nlm.nih.gov/pmc/articles/PMC9709411/
  26. Nov 2022
  27. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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      DOI: 10.1111/bph.15971

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15971
  28. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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      DOI: 10.1111/bph.15954

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15954
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A ketogenic diet in combination with gemcitabine increases survival in pancreatic cancer KPC mice
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      DOI: 10.1158/2767-9764.crc-22-0256

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    ncbi.nlm.nih.gov/pmc/articles/PMC9648418/
  30. academic.oup.com academic.oup.com
    mTOR inhibition decreases angiotensin II-induced steroidogenesis in HAC15 human adrenocortical carcinoma cells
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    1. scibot 19 Nov 2022
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      DOI: 10.1210/endocr/bqac185

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  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    B cell linker protein (BLNK) is a regulator of Met receptor signaling and trafficking in non-small cell lung cancer
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    1. scibot 18 Nov 2022
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      DOI: 10.1016/j.isci.2022.105419

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    ncbi.nlm.nih.gov/pmc/articles/PMC9646953/
  32. www.science.org www.science.org
    Caspase-8 inactivation drives autophagy-dependent inflammasome activation in myeloid cells
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    1. scibot 15 Nov 2022
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      DOI: 10.1126/sciadv.abn9912

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  33. www.science.org www.science.org
    An orally active, small-molecule TNF inhibitor that disrupts the homotrimerization interface improves inflammatory arthritis in mice
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    1. scibot 12 Nov 2022
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      DOI: 10.1126/scisignal.abi8713

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    science.org/doi/10.1126/scisignal.abi8713
  34. www.sciencedirect.com www.sciencedirect.com
    RSPO2 promotes progression of ovarian cancer through dual receptor-mediated FAK/Src signaling activation
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    1. scibot 10 Nov 2022
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      DOI: 10.1016/j.isci.2022.105184

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    sciencedirect.com/science/article/pii/S2589004222014560
  35. Oct 2022
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PKC isoforms activate LRRK1 kinase by phosphorylating conserved residues (Ser1064, Ser1074 and Thr1075) within the CORB GTPase domain
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      DOI: 10.1042/BCJ20220308

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    ncbi.nlm.nih.gov/pmc/articles/PMC9555798/
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Murine endothelial serine palmitoyltransferase 1 (SPTLC1) is required for vascular development and systemic sphingolipid homeostasis
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    1. scibot 26 Oct 2022
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      DOI: 10.7554/eLife.78861

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    ncbi.nlm.nih.gov/pmc/articles/PMC9578713/
  38. www.sciencedirect.com www.sciencedirect.com
    Argininosuccinate lyase drives activation of mutant TERT promoter in glioblastomas
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      DOI: 10.1016/j.molcel.2022.09.024

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    sciencedirect.com/science/article/pii/S1097276522009340
  39. journals.sagepub.com journals.sagepub.com
    Acute Manganese Exposure Modifies the Translation Machinery via PI3K/Akt Signaling in Glial Cells
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      DOI: 10.1177/17590914221131452

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      DOI: 10.1177/17590914221131452

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    journals.sagepub.com/doi/full/10.1177/17590914221131452
  40. www.sciencedirect.com www.sciencedirect.com
    E2F1 transcription factor mediates a link between fat and islets to promote β cell proliferation in response to acute insulin resistance
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      DOI: 10.1016/j.celrep.2022.111436

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    sciencedirect.com/science/article/pii/S2211124722012773
  41. Sep 2022
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    GB83, an Agonist of PAR2 with a Unique Mechanism of Action Distinct from Trypsin and PAR2-AP
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    1. scibot 27 Sep 2022
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      DOI: 10.3390/ijms231810631

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    ncbi.nlm.nih.gov/pmc/articles/PMC9506296/
  43. www.sciencedirect.com www.sciencedirect.com
    Single-cell sequencing reveals activation of core transcription factors in PRC2-deficient malignant peripheral nerve sheath tumor
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      DOI: 10.1016/j.celrep.2022.111363

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    sciencedirect.com/science/article/pii/S2211124722011950
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Opioids Cause Sex-Specific Vascular Changes via Cofilin-Extracellular Signal-Regulated Kinase Signaling: Female Mice Present Higher Risk of Developing Morphine-Induced Vascular Dysfunction than Male Mice
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    1. scibot 21 Sep 2022
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      DOI: 10.1159/000517555

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    ncbi.nlm.nih.gov/pmc/articles/PMC8612963/
  45. www.nature.com www.nature.com
    Integrated multi-omics analysis of adverse cardiac remodeling and metabolic inflexibility upon ErbB2 and ERRα deficiency
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      DOI: 10.1038/s42003-022-03942-4

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    nature.com/articles/s42003-022-03942-4
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sheep recombinant IGF-1 promotes organ-specific growth in fetal sheep
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    Na/K-ATPase Suppresses LPS-Induced Pro-Inflammatory Signaling Through Lyn
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    Chromatin-bound RB targets promoters, enhancers, and CTCF-bound loci and is redistributed by cell-cycle progression
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    Local synthesis of the phosphatidylinositol-3,4-bisphosphate lipid drives focal adhesion turnover
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    Intermittent Theta Burst Stimulation Ameliorates Cognitive Deficit and Attenuates Neuroinflammation via PI3K/Akt/mTOR Signaling Pathway in Alzheimer’s-Like Disease Model
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  69. May 2022
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    Low concentrations of bisphenol A promote the activation of the mitochondrial apoptotic pathway on Beta-TC-6 cells via the generation of intracellular reactive oxygen species and mitochondrial superoxide
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    Lyso-PAF, a biologically inactive phospholipid, contributes to RAF1 activation
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    δ-Tocotrienol is the most potent vitamin E form in inhibiting prostate cancer cell growth and inhibits prostate carcinogenesis in Ptenp-/- mice
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  88. Mar 2022
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    Pathogen size alters C-type lectin receptor signaling in dendritic cells to influence CD4 Th9 cell differentiation
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    A hotspot mutation targeting the R-RAS2 GTPase acts as a potent oncogenic driver in a wide spectrum of tumors
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    Crosstalk between ERK and MRTF-A signaling regulates TGFβ1-induced epithelial-mesenchymal transition
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    A non-bactericidal cathelicidin provides prophylactic efficacy against bacterial infection by driving phagocyte influx
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    Creatine transport and creatine kinase activity is required for CD8+ T cell immunity
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    Identification of the nucleotide-free state as a therapeutic vulnerability for inhibition of selected oncogenic RAS mutants
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    Activating JAK-mutations confer resistance to FLT3 kinase inhibitors in FLT3-ITD positive AML in vitro and in vivo
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    Addition of a carboxy-terminal tail to the normally tailless gonadotropin-releasing hormone receptor impairs fertility in female mice
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    In vivo efficacy of tesevatinib in patient-derived xenograft glioblastoma models may be limited by tissue binding and compensatory signaling
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    p190RhoGAP Filters Competing Signals to Resolve Axon Guidance Conflicts
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    Protein kinase Cι and SRC signaling define reciprocally related subgroups of glioblastoma with distinct therapeutic vulnerabilities
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    MAPK pathway activation selectively inhibits ASCL1-driven small cell lung cancer
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    Costimulation molecules differentially regulate the ERK-Zfp831 axis to shape T follicular helper cell differentiation
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    Regulator of G protein signaling 12 enhances osteoclastogenesis by suppressing Nrf2-dependent antioxidant proteins to promote the generation of reactive oxygen species
    1
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      ERK1/2, rabbit polyclonal

      DOI: 10.7554/eLife.42951

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  182. jbiomedsci.biomedcentral.com jbiomedsci.biomedcentral.com
    Cilostazol inhibits hyperglucose-induced vascular smooth muscle cell dysfunction by modulating the RAGE/ERK/NF-κB signaling pathways
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      ERK antibody

      DOI: 10.1186/s12929-019-0550-9

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  183. www.embopress.org www.embopress.org
    CDK12 drives breast tumor initiation and trastuzumab resistance via WNT and IRS1‐ErbB‐PI3K signaling
    1
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      ERK

      DOI: 10.15252/embr.201948058

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  184. onlinelibrary.wiley.com onlinelibrary.wiley.com
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      AB_330744

      DOI: 10.1111/jnc.14617

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  185. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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      RRID:AB_330744

      DOI: 10.1016/j.celrep.2018.09.060

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  186. academic.oup.com academic.oup.com
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      AB_330744

      DOI: 10.1210/en.2016-1576

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  187. www.sciencedirect.com www.sciencedirect.com
    Widespread Selection for Oncogenic Mutant Allele Imbalance in Cancer
    1
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      RRID:AB_330744

      DOI: 10.1016/j.ccell.2018.10.003

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  188. www.sciencedirect.com www.sciencedirect.com
    The Oncogenic Action of NRF2 Depends on De-glycation by Fructosamine-3-Kinase
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      RRID: AB_330744

      DOI: 10.1016/j.cell.2019.07.031

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  189. www.sciencedirect.com www.sciencedirect.com
    Branched-Chain Amino Acid Metabolic Reprogramming Orchestrates Drug Resistance to EGFR Tyrosine Kinase Inhibitors
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      RRID:AB_330744

      DOI: 10.1016/j.celrep.2019.06.026

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  190. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BRAF Splice Variant Resistance to RAF Inhibitor Requires Enhanced MEK Association
    1
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      RRID:AB_330744

      DOI: 10.1016/j.celrep.2018.10.049

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  191. www.sciencedirect.com www.sciencedirect.com
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      DOI: 10.1016/j.celrep.2018.06.094

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  192. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Exposure to far‐infrared ray attenuates methamphetamine‐induced impairment in recognition memory through inhibition of protein kinase C δ in male mice: Comparison with the antipsychotic clozapine
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      RRID:AB_330744

      DOI: 10.1002/jnr.24228

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  193. academic.oup.com academic.oup.com
    Membrane androgen receptor ZIP9 induces croaker ovarian cell apoptosis via stimulatory G protein alpha subunit and MAPkinase signaling
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      AB_330744

      DOI: 10.1210/en.2017-00087

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  194. academic.oup.com academic.oup.com
    Selective androgen receptor modulator S42 suppresses prostate cancer cell proliferation
    2
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      AB_330744

      DOI: 10.1210/en.2018-00099

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      AB_330744u00a0

      DOI: 10.1210/en.2018-00099

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  195. www.sciencedirect.com www.sciencedirect.com
    Inhibition of LTA4H by bestatin in human and mouse colorectal cancer
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      RRID: AB_330744

      DOI: 10.1016/j.ebiom.2019.05.008

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    sciencedirect.com/science/article/pii/S2352396419303093
  196. www.sciencedirect.com www.sciencedirect.com
    Multi-omic Profiling Reveals Dynamics of the Phased Progression of Pluripotency
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      RRID:AB_330744

      DOI: 10.1016/j.cels.2019.03.012

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  197. www.sciencedirect.com www.sciencedirect.com
    Vitronectin from brain pericytes promotes adult forebrain neurogenesis by stimulating CNTF
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      RRID:AB_330744

      DOI: 10.1016/j.expneurol.2018.11.002

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    sciencedirect.com/science/article/pii/S0014488618306605
  198. academic.oup.com academic.oup.com
    Lithium Chloride Increases COX-2 Expression and PGE2 Production in a Human Granulosa-Lutein SVOG Cell Line Via a GSK-3β/β-Catenin Signaling Pathway
    2
    1. scibot 28 Jul 2021
      AB_330744

      DOI: 10.1210/en.2017-00287

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      RRID:AB_330744

      DOI: 10.1210/en.2017-00287

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  199. onlinelibrary.wiley.com onlinelibrary.wiley.com
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      RRID:AB_330744

      DOI: 10.1111/jnc.13038

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  200. www.nature.com www.nature.com
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      RRID:AB_330744

      DOI: 10.1038/s41540-018-0075-y

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  201. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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      AB_330744

      DOI: 10.1210/en.2017-00693

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    ncbi.nlm.nih.gov/pmc/articles/PMC5761602/
  202. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Intra‐prelimbic cortical inhibition of striatal‐enriched tyrosine phosphatase suppresses cocaine seeking in rats
    1
    1. scibot 27 Jul 2021
      RRID:AB_10695746

      DOI: 10.1111/adb.12504

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    onlinelibrary.wiley.com/doi/10.1111/adb.12504/full
  203. onlinelibrary.wiley.com onlinelibrary.wiley.com
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      RRID:AB_10695746

      DOI: 10.1002/jnr.23622

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      Curator comments: P44/42 MAPK (Erk1/2) Antibody Cell Signaling Technology Cat# 9102 also 9102L, 9102S

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  204. www.jneurosci.org www.jneurosci.org
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      RRID:AB_10695746

      DOI: 10.1523/JNEUROSCI.0864-14.2014

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      RRID:AB_10695746

      DOI: 10.1523/JNEUROSCI.2238-14.2014

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      RRID:AB_823494

      DOI: 10.1523/JNEUROSCI.0569-14.2014

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  207. onlinelibrary.wiley.com onlinelibrary.wiley.com
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      RRID:AB_10695746

      DOI: 10.1002/jnr.23999

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  208. www.sciencedirect.com www.sciencedirect.com
    Maternal separation stress reduced prenatal-ethanol-induced increase in exploratory behaviour and extracellular signal-regulated kinase activity
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      RRID:AB_823494

      DOI: 10.1016/j.bbr.2018.06.004

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  209. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Matriptase activation of Gq drives epithelial disruption and inflammation via RSK and DUOX
    1
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      RRID:AB_330744

      DOI: 10.7554/eLife.66596

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  210. www.sciencedirect.com www.sciencedirect.com
    An iPSC model of hereditary sensory neuropathy-1 reveals L-serine-responsive deficits in neuronal ganglioside composition and axoglial interactions
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      RRID:AB_330744

      DOI: 10.1016/j.xcrm.2021.100345

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    Treprostinil reduces mitochondrial injury during rat renal ischemia-reperfusion injury
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      RRID:AB_330744

      DOI: 10.1016/j.biopha.2021.111912

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  212. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    KY19382, a novel activator of Wnt/β‐catenin signalling, promotes hair regrowth and hair follicle neogenesis
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      RRID:AB_330744

      DOI: 10.1111/bph.15438

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  213. Jun 2021
  214. www.sciencedirect.com www.sciencedirect.com
    Targeting p130Cas- and microtubule-dependent MYC regulation sensitizes pancreatic cancer to ERK MAPK inhibition
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      DOI: 10.1016/j.celrep.2021.109291

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  215. journals.physiology.org journals.physiology.org
    On the potential role of globins in brown adipose tissue: a novel conceptual model and studies in myoglobin knockout mice | American Journal of Physiology-Endocrinology and Metabolism
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      RRID:SCR_015364

      DOI: 10.1152/ajpendo.00662.2020

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  216. www.nature.com www.nature.com
    Cadmium-induced hypertension is associated with renal myosin light chain phosphatase inhibition via increased T697 phosphorylation and p44 mitogen-activated protein kinase levels
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      DOI: 10.1038/s41440-021-00662-w

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