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  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Size-reduced DREADD derivatives for AAV-assisted multimodal chemogenetic control of neuronal activity and behavior
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      DOI: 10.1016/j.crmeth.2024.100881

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    In vivo models of subclonal oncogenesis and dependency in hematopoietic malignancy
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    sciencedirect.com/science/article/pii/S1535610824003970
  4. Nov 2024
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting BCL2 with Venetoclax Enhances the Efficacy of the KRASG12D Inhibitor MRTX1133 in Pancreatic Cancer
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      DOI: 10.1158/0008-5472.CAN-23-3574

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  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Dynamic roles of neutrophil extracellular traps in cancer cell adhesion and activation of Notch 1-mediated epithelial-to-mesenchymal transition in EGFR-driven lung cancer cells
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    1. scibot 07 Nov 2024
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      DOI: 10.3389/fimmu.2024.1470620

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  7. Oct 2024
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Photobiomodulation regulates astrocyte activity and ameliorates scopolamine-induced cognitive behavioral decline
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    ncbi.nlm.nih.gov/pmc/articles/PMC11449862/
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    Arf1-dependent LRBA recruitment to Rab4 endosomes is required for endolysosome homeostasis
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  10. aacrjournals.org aacrjournals.org
    RAF-Mutant Melanomas Differentially Depend on ERK2 Over ERK1 to Support Aberrant MAPK Pathway Activation and Cell Proliferation
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    aacrjournals.org/mcr/article/19/6/1063/672883/RAF-Mutant-Melanomas-Differentially-Depend-on-ERK2
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    Identification of Predictive ERBB Mutations by Leveraging Publicly Available Cell Line Databases
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    aacrjournals.org/mct/article/20/3/564/92877/Identification-of-Predictive-ERBB-Mutations-by
  12. Sep 2024
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    Frontiers | Gestodene, a novel positive allosteric modulator of PAR1, enhances PAR1-mediated human platelet aggregation
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    1. scibot 26 Sep 2024
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    Cancer cell stiffening via CoQ10 and UBIAD1 regulates ECM signaling and ferroptosis in breast cancer
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    1. scibot 25 Sep 2024
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      DOI: 10.1038/s41467-024-52523-y

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    Coagulation factor X promotes resistance to androgen-deprivation therapy in prostate cancer
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    Dietary vitamin B3 supplementation induces the antitumor immunity against liver cancer via biased GPR109A signaling in myeloid cell
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    1. scibot 25 Sep 2024
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    JNK-mediated disruption of bile acid homeostasis promotes intrahepatic cholangiocarcinoma
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    1. scibot 25 Sep 2024
      RRID:AB_330744

      DOI: 10.1073/pnas.2002672117

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    Functional Regeneration of the Sensory Root via Axonal Invasion
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    sciencedirect.com/science/article/pii/S221112471931647X
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    Widespread Selection for Oncogenic Mutant Allele Imbalance in Cancer
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      DOI: 10.1016/j.ccell.2018.10.003

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  20. onlinelibrary.wiley.com onlinelibrary.wiley.com
    The Orphan G Protein‐coupled Receptor 75 Signaling is Activated by the Chemokine CCL5
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      DOI: 10.1111/jnc.14463

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  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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      DOI: 10.3389/fnmol.2018.00212

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    Exposure to far‐infrared ray attenuates methamphetamine‐induced impairment in recognition memory through inhibition of protein kinase C δ in male mice: Comparison with the antipsychotic clozapine
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    1. scibot 25 Sep 2024
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      DOI: 10.1002/jnr.24228

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  23. www.sciencedirect.com www.sciencedirect.com
    Aged fibroblast-derived extracellular vesicles promote angiogenesis in melanoma
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    sciencedirect.com/science/article/pii/S2211124724010726
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Anti-HDGF antibody targets EGFR tyrosine kinase inhibitor-tolerant cells in NSCLC patient-derived xenografts
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    1. scibot 05 Sep 2024
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      DOI: 10.1158/2767-9764.CRC-24-0020

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    A bispecific antibody targeting EGFR and AXL delays resistance to osimertinib
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    Loss of p53 and SMAD4 induces adenosquamous subtype pancreatic cancer in the absence of an oncogenic KRAS mutation
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    sciencedirect.com/science/article/pii/S2666379124004324
  27. Aug 2024
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Soluble Tim-3 serves as a tumor prognostic marker and therapeutic target for CD8+ T cell exhaustion and anti-PD-1 resistance
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    Reiterated Male-to-Female Violence Disrupts Hippocampal Estrogen Receptor β Expression, Prompting Anxiety-Like Behavior
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    Defective endomembrane dynamics in Rab27a deficiency impairs nucleic acid sensing and cytokine secretion in immune cells
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    Ubiquitination and degradation of plant helper NLR by the Ralstonia solanacearum effector RipV2 overcome tomato bacterial wilt resistance
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    Hepatic BMAL1 and HIF1α regulate a time-dependent hypoxic response and prevent hepatopulmonary-like syndrome
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  33. www.cell.com www.cell.com
    Growth differentiation factor 15 alleviates diastolic dysfunction in mice with experimental diabetic cardiomyopathy
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    cell.com/cell-reports/abstract/S2211-1247(24)00902-1
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    In vivo vulnerabilities to GPX4 and HDAC inhibitors in drug-persistent versus drug-resistant BRAFV600E lung adenocarcinoma
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  35. academic.oup.com academic.oup.com
    Exploring visceral and subcutaneous adipose tissue secretomes in human obesity: implications for metabolic disease
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      DOI: 10.1210/endocr/bqac140

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    academic.oup.com/endo/article-abstract/163/11/bqac140/6678177
  36. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Regulation of synaptic MAPK/ERK phosphorylation in the rat striatum and medial prefrontal cortex by dopamine and muscarinic acetylcholine receptors
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      DOI: 10.1002/jnr.23622

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    onlinelibrary.wiley.com/doi/10.1002/jnr.23622/full
  37. www.mdpi.com www.mdpi.com
    Disc Large Homolog 1 Is Critical for Early T Cell Receptor Micro Cluster Formation and Activation in Human T Cells
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      9101

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  38. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Purinergic receptor P2Y6 contributes to 1‐methyl‐4‐phenylpyridinium‐induced oxidative stress and cell death in neuronal SH‐SY5Y cells
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      DOI: 10.1002/jnr.24119

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  39. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Protein kinase A directly phosphorylates metabotropic glutamate receptor 5 to modulate its function
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      DOI: 10.1111/jnc.13038

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    onlinelibrary.wiley.com/doi/10.1111/jnc.13038/full
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    E2F1-associated purine synthesis pathway is a major component of the MET-DNA damage response network
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      DOI: 10.1158/2767-9764.CRC-23-0370

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    ncbi.nlm.nih.gov/pmc/articles/PMC11288008/
  41. Jul 2024
  42. www.sciencedirect.com www.sciencedirect.com
    A Comprehensive Protocol for Efficient Differentiation of Human NPCs into Electrically Competent Neurons
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    sciencedirect.com/science/article/pii/S0165027024001705
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    Human MC4R variants affect endocytosis, trafficking and dimerization revealing multiple cellular mechanisms involved in weight regulation
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      DOI: 10.1016/j.celrep.2021.108862

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    sciencedirect.com/science/article/pii/S2211124721001765
  44. www.sciencedirect.com www.sciencedirect.com
    TERT activation targets DNA methylation and multiple aging hallmarks
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  45. www.cell.com www.cell.com
    Monitoring melanoma patients on treatment reveals a distinct macrophage population driving targeted therapy resistance
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    In silico transcriptome screens identify epidermal growth factor receptor inhibitors as therapeutics for noise-induced hearing loss
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    Cenicriviroc Suppresses and Reverses Steatohepatitis by Regulating Macrophage Infiltration and M2 Polarization in Mice
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    Direct GPCR-EGFR interaction enables synergistic membrane-to-nucleus information transfer
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    Integrative molecular and spatial analysis reveals evolutionary dynamics and tumor-immune interplay of in situ and invasive acral melanoma
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    PDGFRα+ITGA11+ fibroblasts foster early-stage cancer lymphovascular invasion and lymphatic metastasis via ITGA11-SELE interplay
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    The microglial innate immune protein PGLYRP1 mediates neuroinflammation and consequent behavioral changes
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    Trans-omic analysis reveals opposite metabolic dysregulation between feeding and fasting in liver associated with obesity
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    Spatial transcriptomics suggests that alterations occur in the preneoplastic breast microenvironment of BRCA1/2 mutation carriers
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    Loss of STIM2 in colorectal cancer drives growth and metastasis through metabolic reprogramming and PERK-ATF4 endoplasmic reticulum stress pathway
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  92. onlinelibrary.wiley.com onlinelibrary.wiley.com
    l-Methionine potentiates anticancer activity of Sorafenib by epigenetically altering DUSP3/ERK pathway in hepatocellular carcinoma
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    Axon-derived PACSIN1 binds to the Schwann cell survival receptor, LRP1, and transactivates TrkC to promote gliatrophic activities
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    Pim kinase inhibitors increase gilteritinib cytotoxicity in FLT3-ITD acute myeloid leukemia through GSK-3β activation and c-Myc and Mcl-1 proteasomal degradation
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    mTOR regulates mineralocorticoid receptor transcriptional activity by ULK1- dependent and independent mechanisms
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    Membrane-associated NRPM proteins are novel suppressors of stomatal production in Arabidopsis
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    Functional Heterogeneity in MET Pathway Activation in PDX Models of Osimertinib Resistant EGFR-Driven Lung Cancer
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    CHTOP Alleviates Cerebral Ischemia/Reperfusion-Induced Injury by Regulating RNA Alternative Splicing
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    MEK-inhibitors decrease Nfix in muscular dystrophy but induce unexpected calcifications, partially rescued with Cyanidin diet
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  118. Nov 2023
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    Adipo-glial signaling mediates metabolic adaptation in peripheral nerve regeneration
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    Allosteric SHP2 inhibition increases apoptotic dependency on BCL2 and synergizes with venetoclax in FLT3- and KIT-mutant AML
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    GLP-1 and GIP receptors signal through distinct β-arrestin 2-dependent pathways to regulate pancreatic β cell function
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    ASCL1-ERK1/2 Axis: ASCL1 restrains ERK1/2 via the dual specificity phosphatase DUSP6 to promote survival of a subset of neuroendocrine lung cancers
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    TAK1 is an essential kinase for STING trafficking
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    TIM-3 blockade in diffuse intrinsic pontine glioma models promotes tumor regression and antitumor immune memory
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    Oleanolic acid alleviates the extrapyramidal symptoms and cognitive impairment induced by haloperidol through the striatal PKA signaling pathway in mice
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    MAPK-ERK-CREB signaling pathway upregulates Nav1.6 in oxaliplatin-induced neuropathic pain in the rat
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    Tff2 defines transit-amplifying pancreatic acinar progenitors that lack regenerative potential and are protective against Kras-driven carcinogenesis
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    Screening in serum-derived medium reveals differential response to compounds targeting metabolism
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    An improved Erk biosensor detects oscillatory Erk dynamics driven by mitotic erasure during early development
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    RLY-4008, the first highly selective FGFR2 inhibitor with activity across FGFR2 alterations and resistance mutations
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    L858R emerges as a potential biomarker predicting response of lung cancer models to anti-EGFR antibodies: Comparison of osimertinib vs. cetuximab
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    Tumoral P2Y2 receptor modulates tumor growth and host anti-tumor immune responses in a syngeneic murine model of oral cancer
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  144. Jul 2023
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    Banana MKK1 modulates fruit ripening via the MKK1-MPK6-3/11-4-bZIP21 module
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    T lymphocytes expressing the switchable chimeric Fc receptor CD64 exhibit augmented persistence and antitumor activity
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  154. Jun 2023
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    Single-cell transcriptomics of NRAS-mutated melanoma transitioning to drug resistance reveals P2RX7 as an indicator of early drug response
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    Excess pancreatic elastase alters acinar-β cell communication by impairing the mechano-signaling and the PAR2 pathways
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    Optogenetic manipulation identifies the roles of ERK and AKT dynamics in controlling mouse embryonic stem cell exit from pluripotency
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    Deficiency of MicroRNA-23-27-24 Clusters Exhibits the Impairment of Myelination in the Central Nervous System
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