809 Matching Annotations
  1. Aug 2025
  2. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.70158
  3. www.sciencedirect.com www.sciencedirect.com
    Early time window for memory ensemble allocation specifically depending on activity in Syt2+ early-born parvalbumin interneurons
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    sciencedirect.com/science/article/pii/S2211124725009155
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A Four Amino Acid Intracellular Motif of VISTA Blocks Growth Receptor Signaling in Cancer Cells to Induce Tumor Suppression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12317733/
  5. Jul 2025
  6. www.cell.com www.cell.com
    Opsin 5 mediates violet light-accelerated wound healing in mammalian corneas
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    cell.com/cell-reports/fulltext/S2211-1247(25)00816-2
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    Therapeutic targeting of syndecan-1 axis overcomes acquired resistance to KRAS-targeted therapy in gastrointestinal cancers
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    sciencedirect.com/science/article/pii/S266637912500326X
  8. www.biorxiv.org www.biorxiv.org
    Impaired BDNF-TrkB trafficking and signalling in Down syndrome basal forebrain neurons
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    biorxiv.org/content/10.1101/2025.07.15.664857v1
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    Inhibitory Effects of Vandetanib on Catecholamine Synthesis in Rat Pheochromocytoma PC12 Cells
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    mdpi.com/1422-0067/26/14/6927
  10. 52.53.155.43 52.53.155.43
    Pantothenate protects against obesity via brown adipose tissue activation
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    52.53.155.43/7317937cd95e74d813ceb6e8f27034de131d4071/zhou-et-al-2022-pantothenate-protects-against-obesity-via-brown-adipose-tissue-activation-html.html
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    Periodontal Ligaments Enhance Neurite Outgrowth in Trigeminal Ganglion Neurons through Wnt5a Production Induced by Mechanical Stimulation
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    52.53.155.43/f8df4eb8a5eedcbd3583132b5c32fd671a443179/takahashi-et-al-2022-periodontal-ligaments-enhance-neurite-outgrowth-in-trigeminal-ganglion-neurons-through-wnt5a-html.html
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    Neuroendocrine control of intestinal regeneration through the vascular niche in Drosophila
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    sciencedirect.com/science/article/pii/S1534580725004320
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    BRAFV600E augments WNT signaling in colorectal cancer via aberrant DNA methylation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12272824/
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    STX-721, a Covalent EGFR/HER2 Exon 20 Inhibitor, Utilizes Exon 20–Mutant Dynamic Protein States and Achieves Unique Mutant Selectivity Across Human Cancer Models
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    pmc.ncbi.nlm.nih.gov/articles/PMC12260510/
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PHGDH Induction by MAPK is Essential for Melanoma Formation and Creates an Actionable Metabolic Vulnerability
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    pmc.ncbi.nlm.nih.gov/articles/PMC11735329/
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    A Rac-specific competitive inhibitor of guanine nucleotide binding reduces metastasis in triple-negative breast cancer
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    sciencedirect.com/science/article/pii/S2666379125003064
  17. www.nature.com www.nature.com
    Neutrophil extracellular trap gene expression signatures identify prognostic and targetable signaling axes for inhibiting pancreatic tumour metastasis
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    nature.com/articles/s42003-025-08440-x
  18. bmcbiol.biomedcentral.com bmcbiol.biomedcentral.com
    Brain miR-137 governs growth and development via GH/IGF-1 signaling
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    bmcbiol.biomedcentral.com/articles/10.1186/s12915-025-02306-8
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    Cetuximab increases LGR5 expression and augments LGR5-targeting antibody-drug conjugate efficacy in patient-derived colorectal cancer models
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    biorxiv.org/content/10.1101/2025.06.18.660406v1
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    Maternal obesity impairs fetal brown adipogenesis by attenuating fetal FGF21 signaling
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    sciencedirect.com/science/article/pii/S2211124725007065
  21. Jun 2025
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    Plinabulin following radiation enhances dendritic cell maturation and checkpoint inhibitor retreatment of relapsed/refractory cancers
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    sciencedirect.com/science/article/pii/S2666634025001795
  23. 52.53.155.43 52.53.155.43
    ENEURO.0149-16.2017.full-html.html
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  25. www.liebertpub.com www.liebertpub.com
    E3 Ubiquitin Ligase Constitutive Photomorphogenic 1 Regulates Differentiation and Inflammation via MAPK Signaling Pathway in Rabbit Articular Chondrocytes
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    liebertpub.com/doi/10.1089/dna.2022.0664
  26. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Splicing Shift of RAC1 Accelerates Tumorigenesis and Defines a Potent Therapeutic Target in Lung Cancer
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202503322
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mutations in PSEN1 predispose inflammation in an astrocyte model of familial Alzheimer’s disease through disrupted regulated intramembrane proteolysis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12181884/
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mechanistic Understanding of Dexamethasone-Mediated Protection against Remdesivir-Induced Hepatotoxicity
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    pmc.ncbi.nlm.nih.gov/articles/PMC12164689/
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    Piezo1 senses hyphae and initiates host defense against pathogenic fungi
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    sciencedirect.com/science/article/pii/S2211124725006102
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    An integrated proteomic portrait of prostate cancer progression
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    sciencedirect.com/science/article/pii/S2211124725005996
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    CSF1R+ myeloid-monocytic cells drive CAR-T cell resistance in aggressive B cell lymphoma
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    sciencedirect.com/science/article/pii/S1535610825002223
  34. link.springer.com link.springer.com
    RNA polymerase II subunit 5-mediating protein limits TLR4-induced innate immune activation in macrophages by inhibiting IKKβ/NF-κB signaling during sepsis
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    link.springer.com/article/10.1186/s12964-025-02278-w
  35. www.cell.com www.cell.com
    Insulin- and exercise-induced phosphoproteomics of human skeletal muscle identify REPS1 as a regulator of muscle glucose uptake
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    cell.com/cell-reports-medicine/fulltext/S2666-3791(25)00236-8
  36. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Trametinib potentiates anti-PD-1 efficacy in tumors established from chemotherapy-primed pancreatic cancer cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC11614707/
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  38. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    TLR4 endocytosis and endosomal TLR4 signaling are distinct and independent outcomes of TLR4 activation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12116916/
  39. May 2025
  40. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    KRAS G12V mutation-selective requirement for ACSS2 in colorectal adenoma formation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12091147/
  41. journals.plos.org journals.plos.org
    Integrated mathematical and experimental modeling uncovers enhanced EMT plasticity upon loss of the DLC1 tumor suppressor
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    journals.plos.org/ploscompbiol/article
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    Arrestin-biased allosteric modulator of neurotensin receptor 1 alleviates acute and chronic pain
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    sciencedirect.com/science/article/pii/S0092867425005082
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    Hepato-cardiac interorgan communication controls cardiac hypertrophy via combined endocrine-autocrine FGF21 signaling
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    sciencedirect.com/science/article/pii/S2666379125001983
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    Novel high throughput 3D ECM remodeling assay identifies MEK as key driver of fibrotic fibroblast activity
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    sciencedirect.com/science/article/pii/S2590006425003606
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    The gut-brain axis mechanism of normal appetite induced by kynurenic acid
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    GPRASP1 deletion in mice abrogates adverse side effects associated with chronic stimulation of Beta2-adrenoceptor
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    sciencedirect.com/science/article/pii/S0753332225002677
  49. Apr 2025
  50. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A leptin receptor mutation which impairs fertility in ewes causes delayed puberty in male and female mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC11979093/
  51. 52.53.155.43 52.53.155.43
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  52. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Development of potent and selective tetrahydro-β-carboline-based HDAC6 inhibitors with promising activity against triple-negative breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12004265/
  53. 52.53.155.43 52.53.155.43
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    52.53.155.43/d69808ea4370d1da117a4ed24008475ca33f7b43/PDF-html.html
  54. www.embopress.org www.embopress.org
    TLR4 endocytosis and endosomal TLR4 signaling are distinct and independent outcomes of TLR4 activation
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    embopress.org/doi/10.1038/s44319-025-00444-2
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    Unlocking the potential of novel Tetrahydro-β-Carboline-based HDAC6 inhibitors for colorectal Cancer therapy: Design, synthesis and biological evaluation
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    sciencedirect.com/science/article/pii/S0045206825003347
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    Quiescent cell re-entry is limited by macroautophagy-induced lysosomal damage
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    RAF1 kinase contributes to autophagic lysosome reformation
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    Injured tubular epithelia-derived CCN1 promotes the mobilization of fibroblasts toward injury sites after kidney injury
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    sciencedirect.com/science/article/pii/S2589004225004377
  60. Mar 2025
  61. 52.53.155.43 52.53.155.43
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    Lipid-metabolism-focused CRISPR screens identify enzymes of the mevalonate pathway as essential for prostate cancer growth
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    sciencedirect.com/science/article/pii/S2211124725002414
  63. www.biorxiv.org www.biorxiv.org
    In vivo validation of the palmitoylation cycle as a therapeutic target in NRAS-mutant cancer
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    biorxiv.org/content/10.1101/2025.03.20.644389v1
  64. www.sciencedirect.com www.sciencedirect.com
    T-bet+ CXCR3+ B cells drive hyperreactive B-T cell interactions in multiple sclerosis
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    Maternal progesterone and adipose mPRε in pregnancy regulate the embryonic nutritional state
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    sciencedirect.com/science/article/pii/S2211124725002049
  66. link.springer.com link.springer.com
    A phase II trial of mTORC1/2 inhibition in STK11 deficient non small cell lung cancer
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    link.springer.com/article/10.1038/s41698-025-00838-4
  67. www.cell.com www.cell.com
    Realigned transsulfuration drives BRAF-V600E-targeted therapy resistance in melanoma
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    cell.com/cell-metabolism/fulltext/S1550-4131(25)00021-X
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    The NF1 tumor suppressor regulates PD-L1 and immune evasion in melanoma
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    sciencedirect.com/science/article/pii/S2211124725001366
  69. Feb 2025
  70. 52.53.155.43 52.53.155.43
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  71. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Cannabinoid Receptor Type 2 Agonist, GW405833, Reduced the Impacts of MDA-MB-231 Breast Cancer Cells on Bone Cells
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    onlinelibrary.wiley.com/doi/10.1002/cam4.70709
  72. dx.doi.org dx.doi.org
    Progesterone Receptor Signaling Promotes Cancer Associated Fibroblast Mediated Tumorigenicity in ER+ Breast Cancer
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    dx.doi.org/10.1210/endocr/bqae092
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    KRASG12D-driven pentose phosphate pathway remodeling imparts a targetable vulnerability synergizing with MRTX1133 for durable remissions in PDAC
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  74. aacrjournals.org aacrjournals.org
    C/EBPa confers dependence to fatty acid anabolic pathways and vulnerability to lipid oxidative stress-induced ferroptosis in FLT3-mutant leukemia
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    aacrjournals.org/cancerdiscovery/article/13/7/1720/727640/C-EBP-Confers-Dependence-to-Fatty-Acid-Anabolic
  75. aacrjournals.org aacrjournals.org
    ASCL1 restrains ERK1/2 to promote survival of a subset of neuroendocrine lung cancers
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    aacrjournals.org/mct/article/23/12/1789/750248/ASCL1-Restrains-ERK1-2-to-Promote-Survival-of-a
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    pH-sensing GPR68 inhibits vascular smooth muscle cell proliferation through Rap1A
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  77. 52.53.155.43 52.53.155.43
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  78. journals.physiology.org journals.physiology.org
    Altered Sphingolipid Profile in Response to Skeletal Muscle Injury in a Mouse Model of Type 1 Diabetes Mellitus.
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    journals.physiology.org/doi/10.1152/ajpcell.00158.2024
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    Taste receptor type 1 member 3 in osteoclasts regulates osteoclastogenesis via detection of glucose
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    Cellular deconstruction of the human skeletal muscle microenvironment identifies an exercise-induced histaminergic crosstalk
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    Mutations in PSEN1 predispose inflammation in an astrocyte model of familial Alzheimer’s disease through disrupted regulated intramembrane proteolysis
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  83. Jan 2025
  84. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Sympathetic innervation of interscapular brown adipose tissue is not a predominant mediator of Oxytocin (OT)-elicited reductions of body weight gain and adiposity in male diet-induced obese rats
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    Fgfr3 enhancer deletion markedly improves all skeletal features in a mouse model of achondroplasia
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    Maternal circadian rhythms during pregnancy dictate metabolic plasticity in offspring
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    ERK activation waves coordinate mechanical cell competition leading to collective elimination via extrusion of bacterially infected cells
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    Cd99l2 regulates excitatory synapse development and restrains immediate-early gene activation
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