1,434 Matching Annotations
  1. Mar 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Transcription elongation defects link oncogenic SF3B1 mutations to targetable alterations in chromatin landscape
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    sciencedirect.com/science/article/pii/S1097276524001758
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    The RNA binding proteins LARP4A and LARP4B promote sarcoma and carcinoma growth and metastasis
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    ncbi.nlm.nih.gov/pmc/articles/PMC10963253/
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    FEAR antiviral response pathway is independent of interferons and countered by poxvirus proteins
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    nature.com/articles/s41564-024-01646-5
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lupenone improves motor dysfunction in spinal cord injury mice through inhibiting the inflammasome activation and pyroptosis in microglia via the nuclear factor kappa B pathway
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    ncbi.nlm.nih.gov/pmc/articles/PMC10960275/
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    Endurance training increases mitochondrial myoglobin and enhances its interaction with complex IV in rat plantaris muscle
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    onlinelibrary.wiley.com/doi/10.1111/apha.14139
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    MYC dependency in GLS1 and NAMPT is a therapeutic vulnerability in multiple myeloma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10952034/
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    Synchronized assembly of the oxidative phosphorylation system controls mitochondrial respiration in yeast
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    1. scibot 21 Mar 2024
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    sciencedirect.com/science/article/pii/S1534580724001102
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    SUMOylation controls Hu antigen R posttranscriptional activity in liver cancer
    2
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    P-tau217 correlates with neurodegeneration in Alzheimer’s disease, and targeting p-tau217 with immunotherapy ameliorates murine tauopathy
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    sciencedirect.com/science/article/pii/S0896627324001272
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    Female mice display sex-specific differences in cerebrovascular function and subarachnoid haemorrhage-induced injury
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    thelancet.com/journals/ebiom/article/PIIS2352-3964(24)00093-8/abstract
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    Housekeeping U1 snRNA facilitates antiviral innate immunity by promoting TRIM25-mediated RIG-I activation
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    sciencedirect.com/science/article/pii/S2211124724002730
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    Protocol for the isolation of tumor cell-derived extracellular vesicles followed by in vivo metastasis assessment in a murine ovarian cancer model
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    sciencedirect.com/science/article/pii/S2666166724001084
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    Extracellular vesicles as a promising source of lipid biomarkers for breast cancer detection in blood plasma
    1
    1. scibot 09 Mar 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC10914699/
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    SMARCA4 is a haploinsufficient B cell lymphoma tumor suppressor that fine-tunes centrocyte cell fate decisions
    2
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    sciencedirect.com/science/article/pii/S1535610824000552
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    ARID1A orchestrates SWI/SNF-mediated sequential binding of transcription factors with ARID1A loss driving pre-memory B cell fate and lymphomagenesis
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    sciencedirect.com/science/article/pii/S1535610824000540
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    RNA modification-related genes illuminate prognostic signature and mechanism in esophageal squamous cell carcinoma
    1
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    sciencedirect.com/science/article/pii/S2589004224005480
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    Mechanisms of HIV-Mediated Blood-Brain Barrier Compromise and Leukocyte Transmigration under the Current Antiretroviral Era.
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    sciencedirect.com/science/article/pii/S2589004224004577
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    Cellular senescence is associated with the spatial evolution toward a higher metastatic phenotype in colorectal cancer
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    sciencedirect.com/science/article/pii/S2211124724002407
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    Glycerophosphodiesters inhibit lysosomal phospholipid catabolism in Batten disease
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    sciencedirect.com/science/article/pii/S1097276524001254
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    Human cortical neurogenesis is altered via glucocorticoid-mediated regulation of ZBTB16 expression
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    sciencedirect.com/science/article/pii/S0896627324000898
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Stromal-derived NRG1 enables oncogenic KRAS bypass in pancreas cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10621596/
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    Species-specific NLRP3 regulation and its role in CNS autoinflammatory diseases
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    sciencedirect.com/science/article/pii/S2211124724001803
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    PDGFRα+ITGA11+ fibroblasts foster early-stage cancer lymphovascular invasion and lymphatic metastasis via ITGA11-SELE interplay
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    sciencedirect.com/science/article/pii/S1535610824000461
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    The CARD8 inflammasome dictates HIV/SIV pathogenesis and disease progression
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    sciencedirect.com/science/article/pii/S009286742400117X
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    Coordinated ARP2/3 and glycolytic activities regulate the morphological and functional fitness of human CD8+ T cells
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  27. Feb 2024
  28. www.biorxiv.org www.biorxiv.org
    The polyamine transporter ATP13A3 mediates DFMO-induced polyamine uptake in neuroblastoma
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    biorxiv.org/content/10.1101/2024.02.20.581161v1
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    The microglial innate immune protein PGLYRP1 mediates neuroinflammation and consequent behavioral changes
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    sciencedirect.com/science/article/pii/S2211124724001414
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activation of the Wnt/β-catenin/CYP1B1 pathway alleviates oxidative stress and protects the blood-brain barrier under cerebral ischemia/reperfusion conditions
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    ncbi.nlm.nih.gov/pmc/articles/PMC10883507/
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A tangible method to assess native ferroptosis suppressor activity
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    ncbi.nlm.nih.gov/pmc/articles/PMC10985226/
  32. aacrjournals.org aacrjournals.org
    Inhibition of PRL2 upregulates PTEN and attenuates tumor growth in Tp53-deficient sarcoma and lymphoma mouse models
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    aacrjournals.org/cancerrescommun/article/4/1/5/732220/Inhibition-of-PRL2-Upregulates-PTEN-and-Attenuates
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    Single-cell transcriptomics reveals the heterogeneity of the immune landscape of IDH-wildtype high-grade gliomas
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    aacrjournals.org/cancerimmunolres/article/12/2/232/733764/Single-Cell-Transcriptomics-Reveals-the
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    UDP-glucose dehydrogenase supports autophagy-deficient PDAC growth via increasing hyaluronic acid biosynthesis
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    sciencedirect.com/science/article/pii/S2211124724001360
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    Poly(ADP-ribosyl)ation of TIMELESS limits DNA replication stress and promotes stalled fork protection
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    sciencedirect.com/science/article/pii/S2211124724001736
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    Disruption of the Na+/K+-ATPase-purinergic P2X7 receptor complex in microglia promotes stress-induced anxiety
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    sciencedirect.com/science/article/pii/S107476132400044X
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    Sustained antidepressant effects of ketamine metabolite involve GABAergic inhibition-mediated molecular dynamics in aPVT glutamatergic neurons
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    Exercise training adaptations in liver glycogen and glycerolipids require hepatic AMP-activated protein kinase in mice
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    Divergent mechanisms regulate TLR4 expression on peripheral blood mononuclear cells following workload-matched exercise in normoxic and hypoxic environments
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    The IRAK1/IRF5 axis initiates IL-12 response by dendritic cells and control of Toxoplasma gondii infection
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    In vivo CRISPR knockout screen identifies p47 as a suppressor of HER2+ breast cancer metastasis by regulating NEMO trafficking and autophagy flux
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    Suppression of the METTL3-m6A-integrin β1 axis by extracellular acidification impairs T cell infiltration and antitumor activity
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    The importance of proinflammatory failed-repair tubular epithelia as a predictor of diabetic kidney disease progression
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    Signaling via a CD27-TRAF2-SHP-1 axis during naive T cell activation promotes memory-associated gene regulatory networks
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    An anti-CD19/CTLA-4 switch improves efficacy and selectivity of CAR T cells targeting CD80/86-upregulated DLBCL
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    Lumbricus Extract Prevents LPS-Induced Inflammatory Activation of BV2 Microglia and Glutamate-Induced Hippocampal HT22 Cell Death by Suppressing MAPK/NF-κB/NLRP3 Signaling and Oxidative Stress
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    Human YKT6 forms priming complex with STX17 and SNAP29 to facilitate autophagosome-lysosome fusion
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    C/EBPα aggravates renal fibrosis in CKD through the NOX4-ROS-apoptosis pathway in tubular epithelial cells
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    Chronic social defeat stress induces anxiety-like behaviors via downregulation of serotonin transporter in the prefrontal serotonergic system in mice
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    Protocol to reveal the binding partner of secreted housekeeping enzymes in Listeria monocytogenes via in silico prediction to in vivo validation
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    Potent and selective binders of the E3 ubiquitin ligase ZNRF3 stimulate Wnt signaling and intestinal organoid growth
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    Arachidonic acid inhibition of the NLRP3 inflammasome is a mechanism to explain the anti-inflammatory effects of fasting
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    Metabolic remodeling in cardiac hypertrophy and heart failure with reduced ejection fraction occurs independent of transcription factor EB in mice
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    Anti-tumor effects of chemically modified miR-143 lipoplexes in a colorectal cancer pelvic recurrence mouse model are mediated via downregulation of myristoylated alanine-rich C kinase substrate
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    Ovarian ERβ cistrome and transcriptome reveal chromatin interaction with LRH-1
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  115. Nov 2023
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    In silico analysis and theratyping of an ultra-rare CFTR genotype (W57G/A234D) in primary human rectal and nasal epithelial cells
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    Generation of a CRISPR/Cas9-edited Plakoglobin (JUP)knock-out (JMUi001-A-4) iPSC line to model the cardiac phenotype of arrhythmogenic cardiomyopathy
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    Upregulation of Spinal MDGA1 in Rats After Nerve Injury Alters Interactions Between Neuroligin-2 and Postsynaptic Scaffolding Proteins and Increases GluR1 Subunit Surface Delivery in the Spinal Cord Dorsal Horn
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    Release of Histone H3K4-reading transcription factors from chromosomes in mitosis is independent of adjacent H3 phosphorylation
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    Widespread BRCA1/2-independent homologous recombination defects are caused by alterations in RNA-binding proteins
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  136. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Novel ASCT2 Inhibitor, C118P, Blocks Glutamine Transport and Exhibits Antitumour Efficacy in Breast Cancer
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    ASCL1-ERK1/2 Axis: ASCL1 restrains ERK1/2 via the dual specificity phosphatase DUSP6 to promote survival of a subset of neuroendocrine lung cancers
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    Gonacin: A germ cell-derived hormone with glucogenic, orexigenic, and gonadal activities
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    Neutrophils resist ferroptosis and promote breast cancer metastasis through aconitate decarboxylase 1
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    Lysosome damage triggers direct ATG8 conjugation and ATG2 engagement via non-canonical autophagy
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    Irisin reduces amyloid-β by inducing the release of neprilysin from astrocytes following downregulation of ERK-STAT3 signaling
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    Interferon-α promotes neo-antigen formation and preferential HLA-B-restricted antigen presentation in pancreatic β-cells
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    Splicing regulation of GFPT1 muscle-specific isoform and its roles in glucose metabolisms and neuromuscular junction
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    Essential role of the amino-terminal region of Drosha for the Microprocessor function
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    Discordant interactions between YAP1 and polycomb group protein SCML2 determine cell fate
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    Heteronemin promotes iron-dependent cell death in pancreatic cancer
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    Underpinning the food matrix regulation of post-exercise myofibrillar protein synthesis by comparing salmon ingestion versus the sum of its isolated nutrients in healthy young adults
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    Increased alpha-synuclein and neuroinflammation in the substantia nigra triggered by systemic inflammation are reversed by targeted inhibition of the receptor for advanced glycation end products (RAGE)
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    Stimulated myotube contractions regulate membrane-bound and soluble TLR4 to prevent LPS-induced signaling and myotube atrophy in skeletal muscle cells
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    TRβ Agonism Induces Tumor Suppression and Enhances Drug Efficacy in Anaplastic Thyroid Cancer in Female Mice
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    CBFA2T3-GLIS2-dependent pediatric acute megakaryoblastic leukemia is driven by GLIS2 and sensitive to navitoclax
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    Identification of a natural PLA2 inhibitor from the marine fungus Aspergillus sp. c1 for MAFLD treatment that suppressed lipotoxicity by inhibiting the IRE-1α/XBP-1s axis and JNK signaling
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