1,776 Matching Annotations
  1. Apr 2025
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    Circular RMST cooperates with lineage-driving transcription factors to govern neuroendocrine transdifferentiation
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    sciencedirect.com/science/article/pii/S153561082500128X
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    Combination therapy with alisertib enhances the anti-tumor immunity induced by a liver cancer vaccine
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    pmc.ncbi.nlm.nih.gov/articles/PMC11995041/
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    Birch pollen allergen-induced dsDNA release activates cGAS-STING signaling and type 2 immune response in mice
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    sciencedirect.com/science/article/pii/S2589004225005851
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    Cytosolic cytochrome c represses ferroptosis
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    sciencedirect.com/science/article/pii/S1550413125001494
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    DM1 repeat-expanded RNAs confer RNA toxicity as individual nuclear-retained RNAs
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    Engineering TCR-controlled fuzzy logic into CAR T cells enhances therapeutic specificity
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    Synergy and antagonism in the integration of BCR and CD40 signals that control B-cell proliferation
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    Engineered nucleocytosolic vehicles for loading of programmable editors
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    Altered Mitochondrial Bioenergetics and Calcium Kinetics in Young‐Onset PLA2G6 Parkinson's Disease iPSCs
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    Drosophila SPARC collagen IV chaperone-like activity essential for development is unique to the fat body
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    Pyruvate kinase M2 activation reprograms mitochondria in CD8 T cells, enhancing effector functions and efficacy of anti-PD1 therapy
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    Glucagon like peptide-1 modulates urinary sodium excretion in diabetic kidney disease via ENaC activation
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    Lysyl Oxidases Are Necessary for Myometrial Contractility and On-time Parturition in Mice
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    Mitochondrial Damage and ER Stress in CB1 Receptor Antagonist-Induced Apoptosis in Human Neuroblastoma SH-SY5Y Cells
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    Modulating immune responses in alopecia: therapeutic insights and potential targets of antisense oligonucleotides
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    Jorunnamycin A induces apoptosis in pancreatic ductal adenocarcinoma cells, spheroids, and patient-derived organoids by modulating KRAS-mediated survival pathways
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    BCG-trained macrophages couple LDLR upregulation to type I IFN responses and antiviral immunity
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  22. Mar 2025
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    Antagonistic roles for MITF and TFE3 in melanoma plasticity
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    The actin and microtubule network regulator WHAMM is identified as a key kidney disease risk gene
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    Targeted degradation of CDK9 potently disrupts the MYC-regulated network
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    Biochemical characterization of Tau protein changes and amyloid dynamics in a novel non-transgenic rat model of tauopathy
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    Transfer RNA acetylation regulates in vivo mammalian stress signaling
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    Recurrent breakpoints in the BRD4 locus reduce toxicity associated with gene amplification
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    Targeting Replication Fork Processing Synergizes with PARP Inhibition to Potentiate Lethality in Homologous Recombination Proficient Ovarian Cancers
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    Basal cell adhesion molecule (BCAM) promotes mesothelial-to-mesenchymal transition and tumor angiogenesis through paracrine signaling
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    Phosphatase PHLPP1 is an alveolar-macrophage-intrinsic transcriptional checkpoint controlling pulmonary fibrosis
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    Protocol to modulate SUMOylation of a specific protein in budding yeast using chemical genetic approaches
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    Interferon-γ-stimulated antigen-presenting cancer-associated fibroblasts hinder neoadjuvant chemoimmunotherapy efficacy in lung cancer
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    Unveiling IRF4-steered regulation of context-dependent effector programs in CD4+ T cells under Th17- and Treg-skewing conditions
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    Targeting tumor monocyte-intrinsic PD-L1 by rewiring STING signaling and enhancing STING agonist therapy
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    A family of bacterial Josephin-like deubiquitinases with an irreversible cleavage mode
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    Müller cells are activated in response to retinal outer nuclear layer degeneration in rats subjected to simulated weightlessness conditions
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    Rocking during sleep reduces motor deficits and beta-amyloid levels in an Alzheimer’s mouse model
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    Septin 3 regulates memory and L-LTP-dependent extension of endoplasmic reticulum into spines
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    YTHDC1 cooperates with the THO complex to prevent RNA-damage-induced DNA breaks
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    The NF1 tumor suppressor regulates PD-L1 and immune evasion in melanoma
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    Synergistic effects of HO-1 inhibition and chemotherapy on tumor proliferation and immune infiltration: An in vitro and in vivo approach to enhancing prostate cancer treatment
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  50. Feb 2025
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    Divergent responses to SARS-CoV-2 infection in bronchial epithelium with pre-existing respiratory diseases
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    AXL promotes lymphangiogenesis by amplifying VEGF-C-mediated AKT pathway
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    Hepatic sphingomyelin phosphodiesterase 3 promotes steatohepatitis by disrupting membrane sphingolipid metabolism
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    Restraint of inflammasome-driven cytokine responses through the mRNA stability protein TTP
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    E3 ligase SYVN1-mediated polyubiquitination of CPSF6 promotes alternative polyadenylation and antivirus effects of macrophages
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    ASCL1 restrains ERK1/2 to promote survival of a subset of neuroendocrine lung cancers
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    GDF-15 predicts epithelioid hemangioendothelioma aggressiveness and is down-regulated by sirolimus through ATF4/ATF5 suppression
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    ArfGAP2 promotes STING proton channel activity, cytokine transit, and autoinflammation
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    Copper Drives Remodeling of Metabolic State and Progression of Clear Cell Renal Cell Carcinoma
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    mTORC2 Regulates Actin Polymerization in Auditory Cells
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    SLFN11-mediated ribosome biogenesis impairment induces TP53-independent apoptosis
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    Rhodoquinone carries electrons in the mammalian electron transport chain
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    P-cadherin-dependent adhesions are required for single lumen formation and HGF-mediated cell protrusions during epithelial morphogenesis
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    G3BP1 ribonucleoprotein complexes regulate focal adhesion protein mobility and cell migration
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  80. Jan 2025
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    A niche-dependent redox rheostat regulates epithelial stem cell fate in the distal colon
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    Bio-orthogonal tuning of matrix properties during 3D cell culture to induce morphological and phenotypic changes
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    An Autophagy-Targeting Chimera Induces Degradation of Androgen Receptor Mutants and AR-v7 in Castration-Resistant Prostate Cancer
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    Anandamide Inhibits Vascular Smooth Muscle Migration, Endothelial Adhesion Protein Expression and Monocyte Adhesion of Human Coronary Artery Cells
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    Ergothioneine improves healthspan of aged animals by enhancing cGPDH activity through CSE-dependent persulfidation
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