1,415 Matching Annotations
  1. Oct 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Multi-omic human pancreatic islet endoplasmic reticulum and cytokine stress response mapping provides type 2 diabetes genetic insights
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    1. scibot 09 Oct 2024
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      DOI: 10.1016/j.cmet.2024.09.006

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    sciencedirect.com/science/article/pii/S155041312400370X
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    Disruption of cellular plasticity by repeat RNAs in human pancreatic cancer
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    1. scibot 09 Oct 2024
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      DOI: 10.1016/j.cell.2024.09.024

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    sciencedirect.com/science/article/pii/S0092867424010729
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    Simple aneuploidy evades p53 surveillance and promotes niche factor-independent growth in human intestinal organoids
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    1. scibot 08 Oct 2024
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      DOI: 10.1091/mbc.E24-04-0166

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    ncbi.nlm.nih.gov/pmc/articles/PMC11321050/
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Verapamil Prevents Decline of IGF-I in Subjects With Type 1 Diabetes and Promotes β-Cell IGF-I Signaling
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    1. scibot 03 Oct 2024
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      DOI: 10.2337/db23-0256

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    ncbi.nlm.nih.gov/pmc/articles/PMC10545554/
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    RAF-Mutant Melanomas Differentially Depend on ERK2 Over ERK1 to Support Aberrant MAPK Pathway Activation and Cell Proliferation
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    1. scibot 02 Oct 2024
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      DOI: 10.1158/1541-7786.MCR-20-1022

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    aacrjournals.org/mcr/article/19/6/1063/672883/RAF-Mutant-Melanomas-Differentially-Depend-on-ERK2
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    Leucine restriction ameliorates Fusobacterium nucleatum-driven malignant progression and radioresistance in nasopharyngeal carcinoma
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    1. scibot 02 Oct 2024
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    sciencedirect.com/science/article/pii/S266637912400483X
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    Perfluoropentane-based oxygen-loaded nanodroplets reduce microglial activation through metabolic reprogramming
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    1. scibot 02 Oct 2024
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      DOI: 10.4103/NRR.NRR-D-23-01299

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    ncbi.nlm.nih.gov/pmc/articles/PMC11438333/
  9. Sep 2024
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    HSV-1-induced N6-methyladenosine reprogramming via ICP0-mediated suppression of METTL14 potentiates oncolytic activity in glioma
    1
    1. scibot 27 Sep 2024
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    sciencedirect.com/science/article/pii/S2211124724011070
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    Saturation mutagenesis-reinforced functional assays for disease-related genes
    1
    1. scibot 27 Sep 2024
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    sciencedirect.com/science/article/pii/S0092867424009760
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    Geranylgeranylated SCFFBXO10 regulates selective outer mitochondrial membrane proteostasis and function
    1
    1. scibot 26 Sep 2024
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    sciencedirect.com/science/article/pii/S2211124724011343
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    IL-22 resolves MASLD via enterocyte STAT3 restoration of diet-perturbed intestinal homeostasis
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    1. scibot 26 Sep 2024
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    sciencedirect.com/science/article/pii/S1550413124003644
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    Colocalization of cancer-associated biomarkers on single extracellular vesicles for early detection of cancer
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    1. scibot 26 Sep 2024
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    sciencedirect.com/science/article/pii/S1525157824002095
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    Divergent iron regulatory states contribute to heterogeneity in breast cancer aggressiveness
    1
    1. scibot 26 Sep 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11387597/
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    Maternal high-fat diet alters Tet-mediated epigenetic regulation during heart development
    1
    1. scibot 26 Sep 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11388159/
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    DDI2 protease controls embryonic development and inflammation via TCF11/NRF1
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    1. scibot 25 Sep 2024
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    sciencedirect.com/science/article/pii/S2589004224021187
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    Dietary vitamin B3 supplementation induces the antitumor immunity against liver cancer via biased GPR109A signaling in myeloid cell
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    1. scibot 25 Sep 2024
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    sciencedirect.com/science/article/pii/S2666379124004397
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    Intercellular nanotube-mediated mitochondrial transfer enhances T cell metabolic fitness and antitumor efficacy
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    1. scibot 17 Sep 2024
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    sciencedirect.com/science/article/pii/S0092867424009565
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    Multi-omics analysis using antibody-based in situ biotinylation technique suggests the mechanism of Cajal body formation
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    1. scibot 17 Sep 2024
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      DOI: 10.1016/j.celrep.2024.114734

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    sciencedirect.com/science/article/pii/S2211124724010854
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    A nature-inspired HIF stabilizer derived from a highland-adaptation insertion of plateau pika Epas1 protein
    1
    1. scibot 13 Sep 2024
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      DOI: 10.1016/j.celrep.2024.114727

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    sciencedirect.com/science/article/pii/S2211124724010787
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    Phosphorylation of Piezo1 at a single residue, serine-1612, regulates its mechanosensitivity and in vivo mechanotransduction function
    1
    1. scibot 13 Sep 2024
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      DOI: 10.1016/j.neuron.2024.08.009

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    sciencedirect.com/science/article/pii/S0896627324005816
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Recycled melanoma-secreted melanosomes regulate tumor-associated macrophage diversification
    1
    1. scibot 12 Sep 2024
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      DOI: 10.1038/s44318-024-00103-7

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    ncbi.nlm.nih.gov/pmc/articles/PMC11377571/
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    Aged fibroblast-derived extracellular vesicles promote angiogenesis in melanoma
    1
    1. scibot 12 Sep 2024
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      DOI: 10.1016/j.celrep.2024.114721

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    sciencedirect.com/science/article/pii/S2211124724010726
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    Sex-dependent effects in the aged melanoma tumor microenvironment influence invasion and resistance to targeted therapy
    1
    1. scibot 10 Sep 2024
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    sciencedirect.com/science/article/pii/S0092867424009048
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Resistance Training Diminishes Mitochondrial Adaptations to Subsequent Endurance Training in Healthy Untrained Men
    1
    1. scibot 06 Sep 2024
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      DOI: 10.1113/JP284822

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    ncbi.nlm.nih.gov/pmc/articles/PMC11062412/
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    Acutely blocking excessive mitochondrial fission prevents chronic neurodegeneration after traumatic brain injury
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    sciencedirect.com/science/article/pii/S2666379124004361
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    H3K9 lactylation in malignant cells facilitates CD8+ T cell dysfunction and poor immunotherapy response
    1
    1. scibot 04 Sep 2024
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    sciencedirect.com/science/article/pii/S2211124724010374
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    Aldehydes alter TGF-β signaling and induce obesity and cancer
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    sciencedirect.com/science/article/pii/S2211124724010271
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    A chemical screen identifies PRMT5 as a therapeutic vulnerability for paclitaxel-resistant triple-negative breast cancer
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    sciencedirect.com/science/article/pii/S2451945624003234
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    GABAergic neuronal lineage development determines clinically actionable targets in diffuse hemispheric glioma, H3G34-mutant
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  32. Aug 2024
  33. www.sciencedirect.com www.sciencedirect.com
    Confinement controls the directional cell responses to fluid forces
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    1. scibot 29 Aug 2024
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    sciencedirect.com/science/article/pii/S221112472401043X
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    Metabolomics of repetitive myocardial stunning in chronic multivessel coronary artery stenosis: Effect of non-selective and selective β1-receptor blockers
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    physoc.onlinelibrary.wiley.com/doi/10.1113/JP285720
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    MMP9 drives ferroptosis by regulating GPX4 and iron signaling
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    sciencedirect.com/science/article/pii/S2589004224018479
  36. www.cell.com www.cell.com
    MiR-4769-3p suppresses adipogenesis in systemic sclerosis by negatively regulating USP18/VDAC2 pathway
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    cell.com/iscience/abstract/S2589-0042(24)01708-5
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Nephron specific ATP6AP2 knockout increases urinary excretion of fatty acids and decreases renal cortical megalin expression
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    ncbi.nlm.nih.gov/pmc/articles/PMC11319469/
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    Amelioration of nonalcoholic fatty liver disease by inhibiting the deubiquitylating enzyme RPN11
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    cell.com/cell-metabolism/fulltext/S1550-4131(24)00285-7
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    Schwann cell-secreted PGE2 promotes sensory neuron excitability during development
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    Feedforward cysteine regulation maintains melanoma differentiation state and limits metastatic spread
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    ncbi.nlm.nih.gov/pmc/articles/PMC11316253/
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    Integrative plasma and fecal metabolomics identify functional metabolites in adenoma-colorectal cancer progression and as early diagnostic biomarkers
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    Anticancer effects of Erzhimaoling decoction in high-grade serous ovarian cancer in vitro and in vivo
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    ncbi.nlm.nih.gov/pmc/articles/PMC11299366/
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    BCL2L13 at Endoplasmic Reticulum-Mitochondria Contact Sites Regulates Calcium Homeostasis to Maintain Skeletal Muscle Function
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    Generation and characterization of a human iPSC line expressing EGFP-tagged CDH1, KSCBi002-A-3
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  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Exosomal mRNA Cargo are biomarkers of tumor and immune cell populations in pediatric osteosarcoma
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  87. www.biorxiv.org www.biorxiv.org
    Actinomycin D and bortezomib disrupt protein homeostasis in Wilms tumor
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    Dystrophin 71 deficiency causes impaired aquaporin-4 polarization contributing to glymphatic dysfunction and brain edema in cerebral ischemia
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    Placental co-transcriptional activator Vestigial-like 1 (VGLL1) drives tumorigenesis via increasing transcription of proliferation and invasion genes
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    CHK1 inhibitor SRA737 is active in PARP inhibitor resistant and CCNE1 amplified ovarian cancer
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    The phosphorylation-deubiquitination positive feedback loop of the CHK2-USP7 axis stabilizes p53 under oxidative stress
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    RAPSYN-mediated neddylation of BCR-ABL alternatively determines the fate of Philadelphia chromosome-positive leukemia
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    Evaluation of the role of AXL in fusion-positive pediatric rhabdomyosarcoma identifies the small-molecule inhibitor bemcentinib (BGB324) as potent chemosensitizer
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    Metallo-protease Peptidase M84 from Bacillus altitudinis induces ROS-dependent apoptosis in ovarian cancer cells by targeting PAR-1
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    Reversion from basal histone H4 hypoacetylation at the replication fork increases DNA damage in FANCA deficient cells
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    Nucleotide depletion promotes cell fate transitions by inducing DNA replication stress
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    FAK regulates tension transmission to the nucleus and endothelial transcriptome independent of kinase activity
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    Differential regulation of G protein-coupled receptor-associated proteins in the caudate and the putamen of cynomolgus macaques following chronic ethanol drinking
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    The E3 ubiquitin-protein ligase UHRF1 promotes adipogenesis and limits fibrosis by suppressing GPNMB-mediated TGF-β signaling
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    Neither alpha-synuclein fibril strain nor host murine genotype influences seeding efficacy
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    Monocarboxylate transporter 4 deficiency enhances high-intensity interval training-induced metabolic adaptations in skeletal muscle
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    Modulation of prostaglandin transport activity of SLCO2A1 by annexin A2 and S100A10
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  115. journals.physiology.org journals.physiology.org
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    Cryo-EM reveals that iRhom2 restrains ADAM17 protease activity to control the release of growth factor and inflammatory signals
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    Targeting WEE1 enhances the antitumor effect of KRAS-mutated non-small cell lung cancer harboring TP53 mutations
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    Alarmin S100A8 imparts chemoresistance of esophageal cancer by reprogramming cancer-associated fibroblasts
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  121. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Photoacoustic Tomography with Temporal Encoding Reconstruction (PATTERN) for cross-modal individual analysis of the whole brain
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    Deficiency of CBL and CBLB ubiquitin ligases leads to hyper T follicular helper cell responses and lupus by reducing BCL6 degradation
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  163. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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