425 Matching Annotations
  1. Sep 2021
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hepatocyte activity of the cholesterol sensor smoothened regulates cholesterol and bile acid homeostasis in mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC8449244/
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    DOT1L O-GlcNAcylation promotes its protein stability and MLL-fusion leukemia cell proliferation
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    sciencedirect.com/science/article/pii/S221112472101192X
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    Pharmacological inhibition of arachidonate 12-lipoxygenase ameliorates myocardial ischemia-reperfusion injury in multiple species
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    sciencedirect.com/science/article/pii/S1550413121003776
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    A feedback loop between the androgen receptor and 6-phosphogluoconate dehydrogenase (6PGD) drives prostate cancer growth
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    ncbi.nlm.nih.gov/pmc/articles/PMC8416027/
  6. Aug 2021
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    Loss of tyrosine catabolic enzyme HPD promotes glutamine anaplerosis through mTOR signaling in liver cancer
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    sciencedirect.com/science/article/pii/S221112472101055X
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    AMPK ACTIVATION AMELIORATES KIDNEY VASCULAR DYSFUNCTION, OXIDATIVE STRESS AND INFLAMMATION IN OBESITY
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    1. scibot 16 Aug 2021
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15600
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    Identification of response signatures for tankyrase inhibitor treatment in tumor cell lines
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    ncbi.nlm.nih.gov/pmc/articles/PMC8313754/
  10. www.physiology.org www.physiology.org
    Energy metabolism couples hepatocyte integrin-linked kinase to liver glucoregulation and postabsorptive responses of mice in an age-dependent manner
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    1. scibot 14 Aug 2021
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      DOI: 10.1152/ajpendo.00496.2018

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    physiology.org/doi/abs/10.1152/ajpendo.00496.2018
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    ncbi.nlm.nih.gov/pmc/articles/PMC6468262/
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    ncbi.nlm.nih.gov/pmc/articles/PMC5521213/
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    academic.oup.com/endo/article/158/6/1977/3078999
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    ncbi.nlm.nih.gov/pmc/articles/PMC6370974/
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    ncbi.nlm.nih.gov/pmc/articles/PMC5446411/
  17. academic.oup.com academic.oup.com
    Renal Metabolic Programming Is Linked to the Dynamic Regulation of a Leptin-Klf15 Axis and Akt/AMPKα Signaling in Male Offspring of Obese Dams
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    academic.oup.com/endo/article/158/10/3399/4037402/Renal-Metabolic-Programming-Is-Linked-to-the
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Isovitexin-Mediated Regulation of Microglial Polarization in Lipopolysaccharide-Induced Neuroinflammation via Activation of the CaMKKβ/AMPK-PGC-1α Signaling Axis
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    ncbi.nlm.nih.gov/pmc/articles/PMC6868066/
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    ncbi.nlm.nih.gov/pmc/articles/PMC6302735/
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    ncbi.nlm.nih.gov/pmc/articles/PMC5625638/
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    academic.oup.com/endo/article/158/5/1194/2930937
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling
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    ncbi.nlm.nih.gov/pmc/articles/PMC5279869/
  23. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    ncbi.nlm.nih.gov/pmc/articles/PMC6224605/
  25. www.mdpi.com www.mdpi.com
    CRISPR/Cas9-Mediated Knock-Out of KrasG12D Mutated Pancreatic Cancer Cell Lines
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      DOI: 10.3390/ijms20225706

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    mdpi.com/1422-0067/20/22/5706
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    ncbi.nlm.nih.gov/pmc/articles/PMC6344045/
  27. www.fasebj.org www.fasebj.org
    Growth hormone enhances the recovery of hypoglycemia via ventromedial hypothalamic neurons
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      DOI: 10.1096/fj.201901315R

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  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    ncbi.nlm.nih.gov/pmc/articles/PMC6298213/
  29. www.hindawi.com www.hindawi.com
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      DOI: 10.1155/2019/6254269

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    hindawi.com/journals/sci/2019/6254269/
  30. academic.oup.com academic.oup.com
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    academic.oup.com/endo/article/158/7/2226/3788877
  31. Jul 2021
  32. www.sciencedirect.com www.sciencedirect.com
    Lactate Buildup at the Site of Chronic Inflammation Promotes Disease by Inducing CD4+ T Cell Metabolic Rewiring
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      Phospho-AMPKα (Thr172) (40H9) Rabbit mAb

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    sciencedirect.com/science/article/pii/S1550413119305595
  33. www.sciencedirect.com www.sciencedirect.com
    Dysregulation of Mitochondrial Ca2+ Uptake and Sarcolemma Repair Underlie Muscle Weakness and Wasting in Patients and Mice Lacking MICU1
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      Rabbit anti-phospho-AMPKα (Thr172)

      DOI: 10.1016/j.celrep.2019.09.063

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    sciencedirect.com/science/article/pii/S2211124719312604
  34. www.mdpi.com www.mdpi.com
    The Metabolic Inhibitor CPI-613 Negates Treatment Enrichment of Ovarian Cancer Stem Cells
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      Phospho-AMPKα (Thr172)

      DOI: 10.3390/cancers11111678

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    mdpi.com/2072-6694/11/11/1678/htm
  35. onlinelibrary.wiley.com onlinelibrary.wiley.com
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    onlinelibrary.wiley.com/doi/full/10.1002/jcp.26115
  36. www.cell.com www.cell.com
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    cell.com/molecular-cell/abstract/S1097-2765(17)30053-9
  37. www.sciencedirect.com www.sciencedirect.com
    Dietary Sugars Alter Hepatic Fatty Acid Oxidation via Transcriptional and Post-translational Modifications of Mitochondrial Proteins
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      Rabbit Policlonal Anti-172pAMPK/TotAMPK

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  38. www.sciencedirect.com www.sciencedirect.com
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    sciencedirect.com/science/article/pii/S2211124718317649
  39. www.sciencedirect.com www.sciencedirect.com
    Microbially Produced Imidazole Propionate Impairs Insulin Signaling through mTORC1
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    sciencedirect.com/science/article/pii/S0092867418313060
  40. www.sciencedirect.com www.sciencedirect.com
    ER Stress Drives Lipogenesis and Steatohepatitis via Caspase-2 Activation of S1P
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      DOI: 10.1016/j.cell.2018.08.020

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    sciencedirect.com/science/article/pii/S0092867418310365
  41. www.sciencedirect.com www.sciencedirect.com
    mTORC1 Couples Nucleotide Synthesis to Nucleotide Demand Resulting in a Targetable Metabolic Vulnerability
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      Phospho-AMPKα T172

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    sciencedirect.com/science/article/pii/S1535610817304178
  42. www.sciencedirect.com www.sciencedirect.com
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    sciencedirect.com/science/article/pii/S2211124718316486
  43. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    Oral administration of a new HRI activator as a new strategy to improve high‐fat‐diet‐induced glucose intolerance, hepatic steatosis, and hypertriglyceridaemia through FGF21
    1
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      phospho‐AMPK Thr172

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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.14678
  44. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Arctigenin improves lipid metabolism by regulating AMP‐activated protein kinase and downstream signaling pathways
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      phosphou2010AMPKu03b1

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    Hypothalamic Regulation of Liver and Muscle Nutrient Partitioning by Brain-Specific Carnitine Palmitoyltransferase 1C in Male Mice
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      DOI: 10.1210/en.2017-00151

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  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling
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      RRID: AB_331250

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    Genetic Analysis Reveals AMPK Is Required to Support Tumor Growth in Murine Kras-Dependent Lung Cancer Models
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    Serine Synthesis via PHGDH Is Essential for Heme Production in Endothelial Cells
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    Intramuscular Injection of miR-1 Reduces Insulin Resistance in Obese Mice
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    Programmed PPAR-α downregulation induces inflammaging by suppressing fatty acid catabolism in monocytes
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    An mTORC1-GRASP55 signaling axis controls unconventional secretion to reshape the extracellular proteome upon stress
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  53. Jun 2021
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    LKB1/STK11 is a tumor suppressor in the progression of myeloproliferative neoplasms
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    Intracellular H2S production is an autophagy-dependent adaptive response to DNA damage
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    Metformin inhibition of mitochondrial ATP and DNA synthesis abrogates NLRP3 inflammasome activation and pulmonary inflammation
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    Reliance on Cox10 and oxidative metabolism for antigen-specific NK cell expansion
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  58. May 2021
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    The autophagy protein Becn1 improves insulin sensitivity by promoting adiponectin secretion via exocyst binding
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    A PKD-MFF signaling axis couples mitochondrial fission to mitotic progression
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    An octimibate derivative, Oxa17, enhances cholesterol efflux and exerts anti-inflammatory and atheroprotective effects in experimental atherosclerosis
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      phospho-AMPKα (Thr172) (40H9)

      DOI: 10.1016/j.bcp.2021.114581

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    Glycolytic ATP fuels phosphoinositide 3-kinase signaling to support effector T helper 17 cell responses
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    Mitochondrial metabolism supports resistance to IDH mutant inhibitors in acute myeloid leukemia
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      AB_3312502535

      DOI: 10.1084/jem.20200924

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  64. academic.oup.com academic.oup.com
    Removal of epididymal visceral adipose tissue prevents obesity-induced multi-organ insulin resistance in male mice
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      DOI: 10.1210/jendso/bvab024

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    Inositol Polyphosphate Multikinase Inhibits Liquid-Liquid Phase Separation of TFEB to Negatively Regulate Autophagy Activity
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      Rabbit monoclonal anti-Phospho-AMPKα (Thr172) (40H9)

      DOI: 10.1016/j.devcel.2020.10.010

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    Sarcomere function activates a p53-dependent DNA damage response that promotes polyploidization and limits in vivo cell engraftment
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      DOI: 10.1016/j.celrep.2021.109088

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    eEF2/eEF2K Pathway in the Mature Dentate Gyrus Determines Neurogenesis Level and Cognition
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      Anti- Phospho-AMPKα (Thr172) (40H9) Rabbit mAb

      DOI: 10.1016/j.cub.2020.06.061

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    Glutamine Metabolism Controls Chondrocyte Identity and Function
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    Asparagine couples mitochondrial respiration to ATF4 activity and tumor growth
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    The ZMYND8-regulated mevalonate pathway endows YAP-high intestinal cancer with metabolic vulnerability
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  71. Apr 2021
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    PHD3 Loss Promotes Exercise Capacity and Fat Oxidation in Skeletal Muscle
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    Untangling Determinants of Enhanced Health and Lifespan through a Multi-omics Approach in Mice
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    SIRT6-CBP-dependent nuclear Tau accumulation and its role in protein synthesis
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    Energy status dictates PD-L1 protein abundance and anti-tumor immunity to enable checkpoint blockade
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    A Cellular Mechanism to Detect and Alleviate Reductive Stress
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    SETD2 Restricts Prostate Cancer Metastasis by Integrating EZH2 and AMPK Signaling Pathways
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    S1PR3–G12-biased agonist ALESIA targets cancer metabolism and promotes glucose starvation
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    Neuronal cell-based high-throughput screen for enhancers of mitochondrial function reveals luteolin as a modulator of mitochondria-endoplasmic reticulum coupling
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    The phytochemical hyperforin triggers thermogenesis in adipose tissue via a Dlat-AMPK signaling axis to curb obesity
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    Metabolic conditioning of CD8 + effector T cells for adoptive cell therapy
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      anti-phospho-AMPKThr172

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    PKA and AMPK Signaling Pathways Differentially Regulate Luteal Steroidogenesis
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    Theaflavin TF3 relieves hepatocyte lipid deposition through activating AMPK signaling pathway by targeting plasma kallikrein
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    Negative regulation of AMPK signaling by high glucose via E3 ubiquitin ligase MG53
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    Reduced Na+K+‐ATPase activity may reduce amino acid uptake in IUGR fetal sheep muscle despite unchanged ex vivo amino acid transporter activity
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      DOI: 10.1113/JP278933

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    Pulmonary inflammation-induced alterations in key regulators of mitophagy and mitochondrial biogenesis in murine skeletal muscle
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    HCAR1/MCT1 Regulates Tumor Ferroptosis through the Lactate-Mediated AMPK-SCD1 Activity and Its Therapeutic Implications
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    Electrical stimulation prevents doxorubicin-induced atrophy and mitochondrial loss in cultured myotubes
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    Maternal Inactivity Programs Skeletal Muscle Dysfunction in Offspring Mice by Attenuating Apelin Signaling and Mitochondrial Biogenesis
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  99. Nov 2020
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    Linagliptin Ameliorates Hepatic Steatosis via Non-Canonical Mechanisms in Mice Treated with a Dual Inhibitor of Insulin Receptor and IGF-1 Receptor
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    Norepinephrine Regulation of Adrenergic Receptor Expression, 5’ AMP-Activated Protein Kinase Activity, and Glycogen Metabolism and Mass in Male Versus Female Hypothalamic Primary Astrocyte Cultures - Mostafa M. H. Ibrahim, Khaggeswar Bheemanapally, Paul W. Sylvester, Karen P. Briski, 2020
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    Muscle-Liver Trafficking of BCAA-Derived Nitrogen Underlies Obesity-Related Glycine Depletion
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    Effect of Treadmill Exercise and Trans-Cinnamaldehyde against d-Galactose- and Aluminum Chloride-Induced Cognitive Dysfunction in Mice
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  105. Oct 2020
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    BPA differentially regulates NPY expression in hypothalamic neurons through a mechanism involving oxidative stress
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    Phosphorylation of PDHA by AMPK Drives TCA Cycle to Promote Cancer Metastasis
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  108. Sep 2020
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    Mechanism of Activation of AMPK by Cordycepin
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    Low-Dose Sorafenib Acts as a Mitochondrial Uncoupler and Ameliorates Nonalcoholic Steatohepatitis
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    AMPK Preferentially Depresses Retrograde Transport of Axonal Mitochondria during Localized Nutrient Deprivation
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    Dissociation of Adaptive Thermogenesis from Glucose Homeostasis in Microbiome-Deficient Mice
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    FAMIN Is a Multifunctional Purine Enzyme Enabling the Purine Nucleotide Cycle
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    Metformin Enhances Autophagy and Normalizes Mitochondrial Function to Alleviate Aging-Associated Inflammation
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    Microbial Imidazole Propionate Affects Responses to Metformin through p38γ-Dependent Inhibitory AMPK Phosphorylation
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    A FLCN-TFE3 Feedback Loop Prevents Excessive Glycogenesis and Phagocyte Activation by Regulating Lysosome Activity
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    Pimozide Alleviates Hyperglycemia in Diet-Induced Obesity by Inhibiting Skeletal Muscle Ketone Oxidation
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    Effects of acute aerobic, resistance and combined exercises on 24-h glucose variability and skeletal muscle signalling responses in type 1 diabetics
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    Atf-6 Regulates Lifespan through ER-Mitochondrial Calcium Homeostasis
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    Phenformin Inhibits Hedgehog-Dependent Tumor Growth through a Complex I-Independent Redox/Corepressor Module
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    Distinct regulation of bioenergetics and translation by group I mGluR and NMDAR
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      anti‐phospho‐AMPKα

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    Genetic manipulation of LKB1 elicits lethal metastatic prostate cancer
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    14-3-3 proteins protect AMPK-phosphorylated ten-eleven translocation-2 (TET2) from PP2A-mediated dephosphorylation
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      phospho-AMPKα

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    Low-density lipoprotein receptor-related protein 1 deficiency in cardiomyocytes reduces susceptibility to insulin resistance and obesity
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      pAMPK

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  130. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Muscle function and homeostasis require cytokine inhibition of AKT activity in Drosophila
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  131. journals.physiology.org journals.physiology.org
    Electrical stimulation prevents doxorubicin-induced atrophy and mitochondrial loss in cultured myotubes | American Journal of Physiology-Cell Physiology
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  132. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    AMPK-Regulated Astrocytic Lactate Shuttle Plays a Non-Cell-Autonomous Role in Neuronal Survival
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      phospho AMPK Thr172

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  133. journals.physiology.org journals.physiology.org
    Immobilization leads to alterations in intracellular phosphagen and creatine transporter content in human skeletal muscle | American Journal of Physiology-Cell Physiology
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      phosphorylated AMPKThr172

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  134. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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      anti‐rabbit Phospho‐AMPKα

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  136. Jan 2020
  137. elifesciences.org elifesciences.org
    Impaired skeletal muscle mitochondrial pyruvate uptake rewires glucose metabolism to drive whole-body leanness
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    PPM1H phosphatase counteracts LRRK2 signaling by selectively dephosphorylating Rab proteins
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    RAD51AP1 Is an Essential Mediator of Alternative Lengthening of Telomeres
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    CircACC1 Regulates Assembly and Activation of AMPK Complex under Metabolic Stress
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    Translational Regulation of Non-autonomous Mitochondrial Stress Response Promotes Longevity
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    Thyroid-Hormone-Induced Browning of White Adipose Tissue Does Not Contribute to Thermogenesis and Glucose Consumption
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  144. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    Acute activation of endothelial AMPK surprisingly inhibits endothelium‐dependent hyperpolarization‐like relaxations in rat mesenteric arteries
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    Slc6a8-Mediated Creatine Uptake and Accumulation Reprogram Macrophage Polarization via Regulating Cytokine Responses
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    Treg Cells Promote the SREBP1-Dependent Metabolic Fitness of Tumor-Promoting Macrophages via Repression of CD8+ T Cell-Derived Interferon-γ
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    Combination of Hypoglycemia and Metformin Impairs Tumor Metabolic Plasticity and Growth by Modulating the PP2A-GSK3β-MCL-1 Axis
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    Ketosis Ameliorates Renal Cyst Growth in Polycystic Kidney Disease
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  149. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Immunometabolic Cross-Talk and Regulation of Endocrine and Metabolic Functions: Transgenic overexpression of CTRP3 prevents alcohol-induced hepatic triglyceride accumulation
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  150. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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    Transient Receptor Potential V Channels Are Essential for Glucose Sensing by Aldolase and AMPK
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    Heat Shock Factor 1 Is a Direct Antagonist of AMP-Activated Protein Kinase
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    γ-6-Phosphogluconolactone, a Byproduct of the Oxidative Pentose Phosphate Pathway, Contributes to AMPK Activation through Inhibition of PP2A
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  154. elifesciences.org elifesciences.org
    Neuronal TORC1 modulates longevity via AMPK and cell nonautonomous regulation of mitochondrial dynamics in C. elegans
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    A Breakdown in Metabolic Reprogramming Causes Microglia Dysfunction in Alzheimer's Disease
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    AUTACs: Cargo-Specific Degraders Using Selective Autophagy
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    Polyamines Control eIF5A Hypusination, TFEB Translation, and Autophagy to Reverse B Cell Senescence
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    Epstein-Barr-Virus-Induced One-Carbon Metabolism Drives B Cell Transformation
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    Glutamate Signaling in Hepatic Stellate Cells Drives Alcoholic Steatosis
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    Quantitative In Vivo Proteomics of Metformin Response in Liver Reveals AMPK-Dependent and -Independent Signaling Networks
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    Fatty Acid Metabolites Combine with Reduced β Oxidation to Activate Th17 Inflammation in Human Type 2 Diabetes
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    p53 Is a Master Regulator of Proteostasis in SMARCB1-Deficient Malignant Rhabdoid Tumors
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    Inhibition of oncogenic Src induces FABP4-mediated lipolysis via PPARγ activation exerting cancer growth suppression
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    Ca2+-Stimulated AMPK-Dependent Phosphorylation of Exo1 Protects Stressed Replication Forks from Aberrant Resection
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    Metformin Alters Upper Small Intestinal Microbiota that Impact a Glucose-SGLT1-Sensing Glucoregulatory Pathway
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    1. scibot 05 Nov 2018
      RRID:AB_331250

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      RRID:AB_331250
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    sciencedirect.com/science/article/pii/S1550413117305715
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    mTORC1 Inactivation Promotes Colitis-Induced Colorectal Cancer but Protects from APC Loss-Dependent Tumorigenesis
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    1. scibot 05 Nov 2018
      RRID:AB_331250

      Resource used:

      (Cell Signaling Technology Cat# 2535, RRID:AB_331250)

      SciCrunch record: RRID:AB_331250

      Alternate resolvers: SciCrunch xml N2T identifiers.org

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      RRID:AB_331250
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    sciencedirect.com/science/article/pii/S1550413117306745