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Aug 2025
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PKD and scaffold NHERF1 mediate hypoxia-induced gene expression in 3T3-L1 adipocytes

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Effect of 8-Methyl Nonanoic Acid, a Degradation By-Product of Dihydrocapsaicin, on Energy and Glucose Homeostasis in Diet-Induced Obese Mice

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Effect of 8-Methyl Nonanoic Acid, a Degradation By-Product of Dihydrocapsaicin, on Energy and Glucose Homeostasis in Diet-Induced Obese Mice

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Nitroxoline upregulates low-density lipoprotein receptors expression, enhances lipid metabolism, and reduces hepatic steatosis and atherosclerosis in Apoe−/− mice

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Lysosomal TPC2 channel as a new target of chlorpromazine and Clomipramine to induce protective autophagy in L-BMAA-induced neurodegeneration

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Sex-Specific recurrent insulin-induced hypoglycemia (RIIH) effects on ventromedial hypothalamic nucleus astrocyte metabolic sensor expression and glycogen metabolism

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Jul 2025
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Lactoferrin attenuates renal fibrosis and uremic sarcopenia in a mouse model of adenine-induced chronic kidney disease

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High PER1 expression is associated with STK11 mutation and clinical biomarkers of immunotherapy resistance in lung adenocarcinoma

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Divergent sex-specific effects on a ketogenic diet: Male, but not female, mice exhibit oxidative stress and cellular senescence

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Deletion of AMP-activated protein kinase impairs metastasis and is rescued by ROS scavenging or ectopic CD36 expression

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The impact of neuregulin 4 on metabolic dysregulation in lipodystrophy

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Augment proteasome inhibitor efficacy activates CD8+ T cell-mediated antitumor immunity in breast cancer

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Jun 2025
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Cold-inducible GOT1 activates the malate-aspartate shuttle in brown adipose tissue to support fuel preference for fatty acids

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PRPS activity tunes redox homeostasis in Myc-driven lymphoma

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Insulin- and exercise-induced phosphoproteomics of human skeletal muscle identify REPS1 as a regulator of muscle glucose uptake

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EZH2 loss during metabolic stress drives restoration of MHC class I machinery in melanoma

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Aged and BRCA-Mutated Stromal Cells Drive Epithelial Cell Transformation

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The NAMPT enzyme employs a switch that directly senses AMP/ATP and regulates cellular responses to energy stress

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Tomatidine Ameliorates Diabetes-Induced Cognitive Impairment and Tau Hyperphosphorylation Through the AMPK-TFEB Pathway

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Hepato-cardiac interorgan communication controls cardiac hypertrophy via combined endocrine-autocrine FGF21 signaling

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An integrated proteomics approach identifies phosphorylation sites on viral and host proteins that regulate West Nile virus infection

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Apr 2025
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Chitosan alleviates symptoms of Parkinson’s disease by... : Neural Regeneration Research

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1-s2.0-S2589004225007199-main-html.html

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Adenosine Uptake through the Nucleoside Transporter ENT1 Suppresses Antitumor Immunity and T Cell Pyrimidine Synthesis

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Particle uptake by macrophages triggers bifurcated transcriptional pathways that differentially regulate inflammation and lysosomal gene expression

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Astrocyte Glucose-6-phosphorylase-Beta regulates ventromedial hypothalamic nucleus glucose counterregulatory neurotransmission and systemic hormone profiles

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Dietary timing enhances exercise by modulating fat-muscle crosstalk via adipocyte AMPKα2 signaling

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Therapeutic assessment of a novel mitochondrial complex I inhibitor in in vitro and in vivo models of Alzheimer’s disease

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Feb 2025
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Dietary nitrate supplementation mitigates age-related changes at the neuromuscular junction in mice

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TGF-β1-mediated intercellular signaling fuels cooperative cellular invasion

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The protective effects of liraglutide in reducing lipid droplets accumulation and myocardial fibrosis in diabetic cardiomyopathy

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Gut bacterial L-lysine alters metabolism and histone methylation to drive dendritic cell tolerance

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Lithocholic acid binds TULP3 to activate sirtuins and AMPK to slow down ageing

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Lithocholic acid phenocopies anti-ageing effects of calorie restriction

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Resistance to Spindle Inhibitors in Glioblastoma Depends on STAT3 and Therapy Induced Senescence

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The AMPK allosteric activator MK-8722 improves the histology and spliceopathy in myotonic dystrophy type 1 (DM1) skeletal muscle

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Opposing roles for AMPK in regulating distinct mitophagy pathways

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Metformin Mitigates DPP-4 Inhibitor-Induced Breast Cancer Metastasis via Suppression of mTOR Signaling

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Regulation of Glycolysis-Derived L-lactate Production in Astrocytes Rescues the Memory Deficits and Aβ Burden in Early Alzheimer’s Disease Models

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Obese mice have decreased uterine contractility and altered energy metabolism in the uterus at term gestation

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AMPK targets PDZD8 to trigger carbon source shift from glucose to glutamine

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Increased regional activity of a pro-autophagy pathway in schizophrenia as a contributor to sex differences in the disease pathology

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PKD1 mutant clones within cirrhotic livers inhibit steatohepatitis without promoting cancer

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Nesfatin-1 and nesfatin-1-like peptide attenuate hepatocyte lipid accumulation and nucleobindin-1 disruption modulates lipid metabolic pathways

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Photoacoustic Tomography with Temporal Encoding Reconstruction (PATTERN) for cross-modal individual analysis of the whole brain

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Metabolic regulator LKB1 controls adipose tissue ILC2 PD-1 expression and mitochondrial homeostasis to prevent insulin resistance

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Monocyte bioenergetics: An immunometabolic perspective in metabolic dysfunction-associated steatohepatitis

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A 5:2 intermittent fasting regimen ameliorates NASH and fibrosis and blunts HCC development via hepatic PPARα and PCK1

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Thbs1 regulates skeletal muscle mass in a TGFβ-Smad2/3-ATF4-dependent manner

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Endothelial progenitor cells control remodeling of uterine spiral arteries for the establishment of utero-placental circulation

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HDAC10 inhibition represses melanoma cell growth and BRAF inhibitor resistance via upregulating SPARC expression

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The antiprotozoal drug nitazoxanide improves experimental liver fibrosis in mice

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The autophagy inhibitor NSC185058 suppresses mTORC1-mediated protein anabolism in cultured skeletal muscle

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The clinical antiprotozoal drug nitazoxanide and its metabolite tizoxanide extend Caenorhabditis elegans lifespan and healthspan

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Glutamine suppresses senescence and promotes autophagy through glycolysis inhibition-mediated AMPKα lactylation in intervertebral disc degeneration

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Hepatic malonyl-CoA synthesis restrains gluconeogenesis by suppressing fat oxidation, pyruvate carboxylation, and amino acid availability

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Trans-omic analysis reveals opposite metabolic dysregulation between feeding and fasting in liver associated with obesity

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l-Methionine potentiates anticancer activity of Sorafenib by epigenetically altering DUSP3/ERK pathway in hepatocellular carcinoma

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Exercise training adaptations in liver glycogen and glycerolipids require hepatic AMP-activated protein kinase in mice

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Regulation of the intestinal Na+/H+ exchanger NHE3 by AMP-activated kinase is dependent on phosphorylation of NHE3 at S555 and S563

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HDAC10 blockade upregulates SPARC expression thereby repressing melanoma cell growth and BRAF inhibitor resistance

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Neuronal cell-based high-throughput screen for enhancers of mitochondrial function reveals luteolin as a modulator of mitochondria-endoplasmic reticulum coupling

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Mitochondrial-encoded complex I impairment induces a targetable dependency on aerobic fermentation in Hürthle cell carcinoma of the thyroid

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CD73-dependent generation of extracellular adenosine by vascular endothelial cells modulates de novo lipogenesis in adipose tissue

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WNT4 Regulates Cellular Metabolism via Intracellular Activity at the Mitochondria in Breast and Gynecologic Cancers

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Glucose restriction enhances oxidative fiber formation: A multi-omic signal network involving AMPK and CaMK2

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Alternating current electromagnetic field exposure lessens intramyocellular lipid accumulation due to high-fat feeding via enhanced lipid metabolism in mice

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Short salsalate administration affects cell proliferation, metabolism, and inflammation in polycystic kidney disease

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Maternal exercise improves epithelial development of fetal intestine by enhancing apelin signaling and oxidative metabolism

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Blocking AMPKαS496 phosphorylation improves mitochondrial dynamics and hyperglycemia in aging and obesity

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CD36 maintains lipid homeostasis via selective uptake of monounsaturated fatty acids during matrix detachment and tumor progression

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Sex Differences in the Skeletal Muscle Response to a High Fat, High Sucrose Diet in Rats

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Metformin inhibits inflammatory response and endoplasmic reticulum stress to improve hypothalamic aging in obese mice

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Low glucose metabolite 3-phosphoglycerate switches PHGDH from serine synthesis to p53 activation to control cell fate

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Insulin Signaling Is Preserved in Skeletal Muscle During Early Diabetic Ketoacidosis

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The mitochondrial succinate dehydrogenase complex controls the STAT3-IL-10 pathway in inflammatory macrophages

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Enhanced glycolysis-mediated energy production in alveolar stem cells is required for alveolar regeneration

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PRMT4 Facilitates White Adipose Tissue Browning and Thermogenesis by Methylating PPARγ

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2-Deoxyglucose drives plasticity via an adaptive ER stress-ATF4 pathway and elicits stroke recovery and Alzheimer’s resilience

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Signaling mechanisms in renal compensatory hypertrophy revealed by multi-omics

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Restored autophagy is protective against PAK3-induced cardiac dysfunction

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Impacts of High Fructose Diet and Chronic Exercise on Nitric Oxide Synthase and Oxidative Stress in Rat Kidney

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Canagliflozin impairs T cell effector function via metabolic suppression in autoimmunity

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16p11.2 haploinsufficiency reduces mitochondrial biogenesis in brain endothelial cells and alters brain metabolism in adult mice

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Hub genes and key pathways of traumatic brain injury:... : Neural Regeneration Research

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Methionine consumption by cancer cells drives a progressive upregulation of PD-1 expression in CD4 T cells

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A genetic variant of fatty acid amide hydrolase (FAAH) exacerbates hormone-mediated orexigenic feeding in mice

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Snail acetylation by autophagy-derived acetyl-coenzyme A promotes invasion and metastasis of KRAS-LKB1 co-mutated lung cancer cells

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Metformin mitigates renal dysfunction in obese insulin-resistant rats via activation of the AMPK/PPARα pathway

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Live-cell imaging identifies cAMP microdomains regulating β-adrenoceptor-subtype-specific lipolytic responses in human white adipocytes

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Transcriptional-translational conflict is a barrier to cellular transformation and cancer progression

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Nutrient-sensing AgRP neurons relay control of liver autophagy during energy deprivation

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Pyruvate-supported flux through medium-chain ketothiolase promotes mitochondrial lipid tolerance in cardiac and skeletal muscles

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Malonylation of Acetyl-CoA carboxylase 1 promotes hepatic steatosis and is attenuated by ketogenic diet in NAFLD

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Large neutral amino acid levels tune perinatal neuronal excitability and survival

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Mitoguardin2 is Associated with Hyperandrogenism and Regulates Steroidogenesis in Human Ovarian Granulosa Cells

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Exercise-acclimated microbiota improves skeletal muscle metabolism via circulating bile acid deconjugation

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Feb 2023
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Oral metformin transiently lowers post-prandial glucose response by reducing the apical expression of sodium-glucose co-transporter 1 in enterocytes

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Exercise-activated hepatic autophagy via the FN1-α5β1 integrin pathway drives metabolic benefits of exercise

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NRF3 activates mTORC1 arginine-dependently for cancer cell viability

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Rab8a as a mitochondrial receptor for lipid droplets in skeletal muscle

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Cytosolic DNA sensing by cGAS/STING promotes TRPV2-mediated Ca2+ release to protect stressed replication forks

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AMPK is required for recovery from metabolic stress induced by ultrasound microbubble treatment

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Perturbation of placental protein glycosylation by endoplasmic reticulum stress promotes maladaptation of maternal hepatic glucose metabolism

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Targeting BCAT1 combined with α-ketoglutarate triggers metabolic synthetic lethality in glioblastoma

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Vitamin D and lactoferrin attenuate stress-induced colitis in Wistar rats via enhancing AMPK expression with inhibiting mTOR–STAT3 signaling and modulating autophagy

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Pyruvate dehydrogenase kinase supports macrophage NLRP3 inflammasome activation during acute inflammation

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Blocking AMPK β1 myristoylation enhances AMPK activity and protects mice from high-fat diet-induced obesity and hepatic steatosis

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Lysine crotonylation regulates leucine-deprivation-induced autophagy by a 14-3-3ε-PPM1B axis

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Fluorinated triphenylphosphonium analogs improve cell selectivity and in vivo detection of mito-metformin

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Muscle Wasting: Cellular and Molecular Mechanisms: Chemotherapy agents reduce protein synthesis and ribosomal capacity in myotubes independent of oxidative stress

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Laminin-α4 negatively regulates adipocyte beiging through the suppression of AMPKα in male mice

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Liver autophagy-induced valine and leucine in plasma reflect the metabolic effect of sodium glucose co-transporter 2 inhibitor dapagliflozin

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A ketogenic diet in combination with gemcitabine increases survival in pancreatic cancer KPC mice

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BPS Publications

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Ribosome stalling is a signal for metabolic regulation by the ribotoxic stress response

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Induction of the hepatic aryl hydrocarbon receptor by alcohol dysregulates autophagy and phospholipid metabolism via PPP2R2D

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Acute Manganese Exposure Modifies the Translation Machinery via PI3K/Akt Signaling in Glial Cells

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Destabilization of TP53 by USP10 is essential for neonatal autophagy and survival

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Sex Dimorphic Glucose Transporter-2 Regulation of Hypothalamic Astrocyte Glucose and Energy Sensor Expression and Glycogen Metabolism

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GABP couples oncogene signaling to telomere regulation in TERT promoter mutant cancer

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Rates of protein synthesis are maintained in brain but reduced in skeletal muscle during dietary sulfur amino acid restriction

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Effects of cereblon on stress-activated redox proteins and core behavior

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Genetic impairment of succinate metabolism disrupts bioenergetic sensing in adrenal neuroendocrine cancer

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Skeletal progenitors preserve proliferation and self-renewal upon inhibition of mitochondrial respiration by rerouting the TCA cycle

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Phosphoproteomics of three exercise modalities identifies canonical signaling and C18ORF25 as an AMPK substrate regulating skeletal muscle function

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Pathological mitophagy disrupts mitochondrial homeostasis in Leber’s hereditary optic neuropathy

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GCN2 inhibition sensitizes arginine-deprived hepatocellular carcinoma cells to senolytic treatment

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can-21-3868-html.html

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AMPK-mediated potentiation of GABAergic signalling drives hypoglycaemia-provoked spike-wave seizures

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Glycogen phosphorylase isoform regulation of glucose and Energy Sensor expression in male versus female rat hypothalamic astrocyte primary cultures

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Muscle satellite cells are impaired in type 2 diabetic mice by elevated extracellular adenosine

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Elevated levels of follicular fatty acids induce ovarian inflammation via ERK1/2 and inflammasome activation in PCOS

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academic.oup.com/jcem/advance-article/doi/10.1210/clinem/dgac281/6581607
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Deficiency of C1QL1 reduced murine ovarian follicle reserve through intraovarian and endocrine control

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BPS Publications

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Gold(III)-P-chirogenic complex induce mitochondrial dysfunction in triple-negative breast cancer

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Identification of myo-inositol-binding proteins by using the biotin pull-down strategy in cultured cells

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Caspase cleavage and nuclear retention of the energy sensor AMPK-α1 during apoptosis

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BPS Publications

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Stress-induced autonomic dysregulation of mitochondrial function in the rat urothelium

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Parallel kinase pathways stimulate actin polymerization at depolarized mitochondria

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TIGAR deficiency enhances skeletal muscle thermogenesis by increasing neuromuscular junction cholinergic signaling

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The anti-diabetic drug metformin regulates voltage-gated sodium channel NaV1.7 via the ubiquitin-ligase NEDD4-2

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The Protective Effects of Trans-Cinnamaldehyde against D-Galactose and Aluminum Chloride-Induced Cognitive Dysfunction in Mice

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Age-associated decline of MondoA drives cellular senescence through impaired autophagy and mitochondrial homeostasis

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Probiotics counteract hepatic steatosis caused by ketogenic diet and upregulate AMPK signaling in a model of infantile epilepsy

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Supplementing Soy-Based Diet with Creatine in Rats: Implications for Cardiac Cell Signaling and Response to Doxorubicin

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A mouse model of inherited choline kinase β-deficiency presents with specific cardiac abnormalities and a predisposition to arrhythmia

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PHLPP1 promotes neutral lipid accumulation through AMPK/ChREBP dependent lipid uptake and fatty acid synthesis pathways

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Withaferin A alleviates ethanol-induced liver injury by inhibiting hepatic lipogenesis

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AMPK-PERK axis represses oxidative metabolism and enhances apoptotic priming of mitochondria in acute myeloid leukemia

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Ocimum basilicum but not Ocimum gratissimum present cytotoxic effects on human breast cancer cell line MCF-7, inducing apoptosis and triggering mTOR/Akt/p70S6K pathway

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Acetyl-CoA derived from hepatic mitochondrial fatty acid β-oxidation aggravates inflammation by enhancing p65 acetylation

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ajpcell.00116.2021-html.html

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Electroconvulsive seizure inhibits the mTOR signaling pathway via AMPK in the rat frontal cortex

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Inhibition of glucose transport synergizes with chemical or genetic disruption of mitochondrial metabolism and suppresses TCA cycle-deficient tumors

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Metformin alleviates stress-induced cellular senescence of aging human adipose stromal cells and the ensuing adipocyte dysfunction

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Rheb-regulated mitochondrial pyruvate metabolism of Schwann cells linked to axon stability

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Mitophagy in the basolateral amygdala mediates increased anxiety induced by aversive social experience

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Hepatocyte activity of the cholesterol sensor smoothened regulates cholesterol and bile acid homeostasis in mice

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Inositol serves as a natural inhibitor of mitochondrial fission by directly targeting AMPK

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A feedback loop between the androgen receptor and 6-phosphogluoconate dehydrogenase (6PGD) drives prostate cancer growth

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Loss of tyrosine catabolic enzyme HPD promotes glutamine anaplerosis through mTOR signaling in liver cancer

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AMPK ACTIVATION AMELIORATES KIDNEY VASCULAR DYSFUNCTION, OXIDATIVE STRESS AND INFLAMMATION IN OBESITY

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GDF15 mediates the metabolic effects of PPARβ/δ by activating AMPK

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Energy metabolism couples hepatocyte integrin-linked kinase to liver glucoregulation and postabsorptive responses of mice in an age-dependent manner

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Untitled document

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Untitled document

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AMPK activation reverts mouse epiblast stem cells to naive state

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ncbi.nlm.nih.gov/pmc/articles/PMC8283141/
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Impairment of Angiogenesis by Fatty Acid Synthase Inhibition Involves mTOR Malonylation

1
1. scibot 03 Aug 2021
  
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  RRID:AB_330331
  
  DOI: 10.1016/j.cmet.2018.07.019
  
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  RRID:AB_330331
  
  DOI: 10.1186/s12933-017-0603-x
  
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1. scibot 01 Aug 2021
  
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  RRID:AB_330331
  
  DOI: 10.1016/j.celrep.2018.12.036
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6344045/
Jul 2021
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Protective effect of exercise training against the progression of Alzheimer’s disease in 3xTg-AD mice

1
1. scibot 31 Jul 2021
  
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  rabbit anti-AMPKα
  
  DOI: 10.1016/j.bbr.2019.112105
  
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Dysregulation of Mitochondrial Ca2+ Uptake and Sarcolemma Repair Underlie Muscle Weakness and Wasting in Patients and Mice Lacking MICU1

1
1. scibot 31 Jul 2021
  
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  Rabbit anti-AMPKα
  
  DOI: 10.1016/j.celrep.2019.09.063
  
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sciencedirect.com/science/article/pii/S2211124719312604
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  DOI: 10.1002/jcp.26115
  
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onlinelibrary.wiley.com/doi/full/10.1002/jcp.26115
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Dietary Sugars Alter Hepatic Fatty Acid Oxidation via Transcriptional and Post-translational Modifications of Mitochondrial Proteins

2
1. scibot 30 Jul 2021
  
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  2532
  
  DOI: 10.1016/j.cmet.2019.09.003
  
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2. scibot 30 Jul 2021
  
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  Rabbit Policlonal Anti-172pAMPK/TotAMPK
  
  DOI: 10.1016/j.cmet.2019.09.003
  
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sciencedirect.com/science/article/pii/S1550413119305042
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mTORC1 Couples Nucleotide Synthesis to Nucleotide Demand Resulting in a Targetable Metabolic Vulnerability

1
1. scibot 29 Jul 2021
  
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  AMPKα
  
  DOI: 10.1016/j.ccell.2017.09.013
  
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Glutamine Metabolism Regulates Proliferation and Lineage Allocation in Skeletal Stem Cells

1
1. scibot 28 Jul 2021
  
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  RRID: AB_330331
  
  DOI: 10.1016/j.cmet.2019.01.016
  
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sciencedirect.com/science/article/pii/S1550413119300166
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Oral administration of a new HRI activator as a new strategy to improve high‐fat‐diet‐induced glucose intolerance, hepatic steatosis, and hypertriglyceridaemia through FGF21

1
1. scibot 28 Jul 2021
  
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  AMPK
  
  DOI: 10.1111/bph.14678
  
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bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.14678
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Arctigenin improves lipid metabolism by regulating AMP‐activated protein kinase and downstream signaling pathways

1
1. scibot 28 Jul 2021
  
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  AMPKu03b1
  
  DOI: 10.1002/jcb.28602
  
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onlinelibrary.wiley.com/doi/full/10.1002/jcb.28602
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Clk1 –regulated aerobic glycolysis is involved in gliomas chemoresistance

1
1. scibot 28 Jul 2021
  
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  AB_330331
  
  DOI: 10.1111/jnc.14096
  
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onlinelibrary.wiley.com/doi/10.1111/jnc.14096/full
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Untitled document

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1. scibot 27 Jul 2021
  
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  RRID:AB_330331
  
  DOI: 10.1016/j.celrep.2018.09.065
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6280974/
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1. scibot 27 Jul 2021
  
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  RRID:AB_330331
  
  DOI: 10.1016/j.chembiol.2017.05.021
  
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Spatiotemporal Control of ULK1 Activation by NDP52 and TBK1 during Selective Autophagy

1
1. scibot 27 Jul 2021
  
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  RRID:AB_10694064
  
  DOI: 10.1016/j.molcel.2019.02.010
  
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sciencedirect.com/science/article/pii/S1097276519301005

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